{"reactions": [{"subsystem": "Exchange with the environment", "name": "Nicotinate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"nac_e": -1.0}, "id": "EX00253", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Ascaroside 5 exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"ascr5_e": -1.0}, "id": "EXC0161", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Sulfite transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"so3_c": -1.0, "na1_c": -1.0, "so3_e": 1.0, "na1_e": 1.0}, "id": "TCE5369", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "3-Hydroxypropanoate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"3hpp_c": -1.0, "3hpp_e": 1.0}, "id": "TCE5368", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "5-Oxoproline transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"5oxpro_e": -1.0, "na1_c": 2.0, "na1_e": -2.0, "5oxpro_c": 1.0}, "id": "TCE5361", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "5,6-Dihydrothymine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"56dthm_c": -1.0, "56dthm_e": 1.0}, "id": "TCE5360", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "5,6-dihydrouracil transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"56dura_e": 1.0, "56dura_c": -1.0}, "id": "TCE5363", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "3-Methyl-2-oxobutanoate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"3mob_e": -1.0, "3mob_c": 1.0}, "id": "TCE5362", "gene_reaction_rule": ""}, {"subsystem": "Synthesis and degradation of ketone bodies", "name": "(S)-3-hydroxy-3-methylglutaryl-CoA acetoacetate-lyase (acetyl-CoA-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01360", "ec-code": "4.1.3.4", "sbo": "SBO:0000176"}, "metabolites": {"accoa_m": 1.0, "acac_m": 1.0, "hmgcoa_m": -1.0}, "id": "RM01360", "gene_reaction_rule": "WBGene00022150"}, {"subsystem": "Transport", "name": "3-Hydroxy-2-methylpropanoate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"3hmp_e": 1.0, "3hmp_c": -1.0}, "id": "TCE5364", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "D-Glyceraldehyde transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"na1_c": 1.0, "glyald_e": -1.0, "na1_e": -1.0, "glyald_c": 1.0}, "id": "TCE5367", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Succinic semialdehyde transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"sucsal_c": -1.0, "sucsal_e": 1.0}, "id": "TCE5366", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "beta cyanoalanine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"cyanala_e": -1.0}, "id": "EX02512", "gene_reaction_rule": ""}, {"subsystem": "Vitamin B6 metabolism", "name": "ATP:pyridoxamine 5-phosphotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02493", "ec-code": "2.7.1.35", "sbo": "SBO:0000176"}, "metabolites": {"pydam_c": -1.0, "pyam5p_c": 1.0, "adp_c": 1.0, "atp_c": -1.0, "h_c": 1.0}, "id": "RC02493", "gene_reaction_rule": "WBGene00019008"}, {"subsystem": "Steroid hormone biosynthesis", "name": "dihydrotestosterone:NADP+ delta4-oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02497", "ec-code": "1.3.1.22", "sbo": "SBO:0000176"}, "metabolites": {"5adtststerone_c": 1.0, "nadp_c": 1.0, "nadph_c": -1.0, "tststerone_c": -1.0, "h_c": -1.0}, "id": "RC02497", "gene_reaction_rule": "WBGene00007102 or WBGene00009635"}, {"subsystem": "Transport", "name": "D-Mannose transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"man_e": -1.0, "man_c": 1.0}, "id": "TCE0424", "gene_reaction_rule": ""}, {"subsystem": "Sphingolipid metabolism", "name": "Acyl-CoA:sphingosylphosphorylcholine N-acyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R02543", "ec-code": "2.3.1.24", "sbo": "SBO:0000176"}, "metabolites": {"sphmyln_ce_c": 1.0, "Rtotalcoa_c": -1.0, "coa_c": 1.0, "spc_ce_c": -1.0, "h_c": 1.0}, "id": "RC02543", "gene_reaction_rule": "WBGene00002043 or WBGene00002044 or WBGene00006505"}, {"subsystem": "Purine metabolism", "name": "2-Deoxyadenosine 5-diphosphate:oxidized-thioredoxin 2-oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02017", "ec-code": "1.17.4.1", "sbo": "SBO:0000176"}, "metabolites": {"dadp_c": 1.0, "h2o_c": 1.0, "trdox_c": 1.0, "trdrd_c": -1.0, "adp_c": -1.0}, "id": "RC02017", "gene_reaction_rule": "WBGene00004391 and WBGene00004392 and (WBGene00017610 or WBGene00019055)"}, {"subsystem": "Pyrimidine metabolism", "name": "NADPH:oxidized-thioredoxin oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02016", "ec-code": "1.8.1.9", "sbo": "SBO:0000176"}, "metabolites": {"trdox_c": -1.0, "nadp_c": 1.0, "nadph_c": -1.0, "h_c": -1.0, "trdrd_c": 1.0}, "id": "RC02016", "gene_reaction_rule": "WBGene00015553"}, {"subsystem": "Glycosylphosphatidylinositol(GPI)-anchor biosynthesis", "name": "UDP-N-acetyl-D-glucosamine:phosphatidylinositol N-acetyl-D-glucosaminyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R05916", "ec-code": "2.4.1.198", "sbo": "SBO:0000176"}, "metabolites": {"uacgam_c": -1.0, "udp_c": 1.0, "acgpail_c": 1.0, "pail_c": -1.0, "h_c": 1.0}, "id": "RC05916", "gene_reaction_rule": "WBGene00008504 or WBGene00011860 or WBGene00008431"}, {"subsystem": "Purine metabolism", "name": "2-Deoxyguanosine 5-diphosphate:oxidized-thioredoxin 2-oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02019", "ec-code": "1.17.4.1", "sbo": "SBO:0000176"}, "metabolites": {"trdox_c": 1.0, "h2o_c": 1.0, "dgdp_c": 1.0, "gdp_c": -1.0, "trdrd_c": -1.0}, "id": "RC02019", "gene_reaction_rule": "WBGene00004391 and WBGene00004392 and (WBGene00017610 or WBGene00019055)"}, {"subsystem": "Pyrimidine metabolism", "name": "2-Deoxyuridine 5-diphosphate:oxidized-thioredoxin 2-oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02018", "ec-code": "1.17.4.1", "sbo": "SBO:0000176"}, "metabolites": {"udp_c": -1.0, "trdox_c": 1.0, "trdrd_c": -1.0, "h2o_c": 1.0, "dudp_c": 1.0}, "id": "RC02018", "gene_reaction_rule": "WBGene00004391 and WBGene00004392 and (WBGene00017610 or WBGene00019055)"}, {"subsystem": "Cyanoamino acid metabolism", "name": "alpha-Aminopropiononitrile aminohydrolase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R03542", "ec-code": "3.5.5.1", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -2.0, "nh4_c": 1.0, "ala-L_c": 1.0, "aprop_c": -1.0}, "id": "RC03542", "gene_reaction_rule": "WBGene00014206"}, {"subsystem": "Glutathione metabolism", "name": "L-cysteinylglycine dipeptidase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00899", "ec-code": ["3.4.11.1", "3.4.11.2"], "sbo": "SBO:0000176"}, "metabolites": {"cys-L_c": 1.0, "h2o_c": -1.0, "gly_c": 1.0, "cgly_c": -1.0}, "id": "RC00899", "gene_reaction_rule": "(WBGene00002249 or WBGene00002250) or WBGene00011587"}, {"subsystem": "Aminoacyl-tRNA biosynthesis", "name": "L-Phenylalanine:tRNA(Ala) ligase (AMP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03660", "ec-code": "6.1.1.20", "sbo": "SBO:0000176"}, "metabolites": {"trnaphe_c": -1.0, "atp_c": -1.0, "ppi_c": 1.0, "amp_c": 1.0, "phetrna_c": 1.0, "phe-L_c": -1.0}, "id": "RC03660", "gene_reaction_rule": "WBGene00001497 and WBGene00001498"}, {"subsystem": "Cysteine and methionine metabolism", "name": "L-Cysteine:oxygen oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00893", "ec-code": "1.13.11.20", "sbo": "SBO:0000176"}, "metabolites": {"cys-L_c": -1.0, "3sala_c": 1.0, "h_c": 2.0, "o2_c": -1.0}, "id": "RC00893", "gene_reaction_rule": "WBGene00018986"}, {"subsystem": "Cysteine and methionine metabolism", "name": "O3-acetyl-L-serine:hydrogen-sulfide 2-amino-2-carboxyethyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00897", "ec-code": "2.5.1.47", "sbo": "SBO:0000176"}, "metabolites": {"cys-L_c": 1.0, "ac_c": 1.0, "acser_c": -1.0, "h_c": 1.0, "h2s_c": -1.0}, "id": "RC00897", "gene_reaction_rule": "WBGene00008490 or WBGene00008732 or WBGene00019094 or WBGene00020797 or WBGene00007653 or WBGene00010759 or WBGene00019962 or WBGene00019096"}, {"subsystem": "Cysteine and methionine metabolism", "name": "L-Cysteine:2-oxoglutarate aminotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00895", "ec-code": "2.6.1.1", "sbo": "SBO:0000176"}, "metabolites": {"akg_c": -1.0, "cys-L_c": -1.0, "glu-L_c": 1.0, "mercppyr_c": 1.0}, "id": "RC00895", "gene_reaction_rule": "WBGene00020146 or WBGene00016652 or WBGene00015778"}, {"subsystem": "Glutathione metabolism", "name": "L-glutamate:L-cysteine gamma-ligase (ADP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00894", "ec-code": "6.3.2.2", "sbo": "SBO:0000176"}, "metabolites": {"pi_c": 1.0, "atp_c": -1.0, "glu-L_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "cys-L_c": -1.0, "glucys_c": 1.0}, "id": "RC00894", "gene_reaction_rule": "WBGene00001527 or WBGene00017084"}, {"subsystem": "Primary bile acid biosynthesis", "name": "oxysterol 7alpha-hydroxylase (acting on 25-hydroxycholesterol)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R07209", "ec-code": "1.14.13.100", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "h2o_c": 1.0, "nadp_c": 1.0, "xol25oh_c": -1.0, "h_c": -1.0, "nadph_c": -1.0, "xoltri25_c": 1.0}, "id": "RC07209", "gene_reaction_rule": ""}, {"subsystem": "Fatty acid elongation", "name": "trans-Dodec-2-enoyl-CoA reductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03856", "ec-code": "1.3.1.38", "sbo": "SBO:0000176"}, "metabolites": {"dd2coa_m": -1.0, "nadph_m": -1.0, "h_m": -1.0, "nadp_m": 1.0, "ddcacoa_m": 1.0}, "id": "RM03856", "gene_reaction_rule": "WBGene00012375 or WBGene00012970"}, {"subsystem": "Fatty acid metabolism", "name": "Lauroyl-CoA:(acceptor) 2,3-oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R03857", "ec-code": "1.3.8.7", "sbo": "SBO:0000176"}, "metabolites": {"dd2coa_m": 1.0, "etfox_m": -1.0, "ddcacoa_m": -1.0, "etfrd_m": 1.0}, "id": "RM03857", "gene_reaction_rule": "(WBGene00020812 or WBGene00019406 or WBGene00020366)"}, {"subsystem": "Fatty acid elongation", "name": "Lauroyl-CoA:acetyl-CoA C-acyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R03858", "ec-code": "2.3.1.16", "sbo": "SBO:0000176"}, "metabolites": {"accoa_m": 1.0, "coa_m": -1.0, "3otdcoa_m": -1.0, "ddcacoa_m": 1.0}, "id": "RM03858", "gene_reaction_rule": "WBGene00015125 or WBGene00009952"}, {"subsystem": "Cyanoamino acid metabolism", "name": "L-cysteine hydrogen-sulfide-lyase (adding HCN)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R03524", "ec-code": "4.4.1.9", "sbo": "SBO:0000176"}, "metabolites": {"h2s_m": 1.0, "cyan_m": -1.0, "h_m": 1.0, "cyanala_m": 1.0, "cys-L_m": -1.0}, "id": "RM03524", "gene_reaction_rule": "WBGene00010759"}, {"subsystem": "Glycine, serine and threonine metabolism", "name": "5,10-Methylenetetrahydrofolate:glycine hydroxymethyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00945", "ec-code": "2.1.2.1", "sbo": "SBO:0000176"}, "metabolites": {"ser-L_c": -1.0, "h2o_c": 1.0, "thf_c": -1.0, "mlthf_c": 1.0, "gly_c": 1.0}, "id": "RC00945", "gene_reaction_rule": "WBGene00003214"}, {"subsystem": "Cysteine and methionine metabolism", "name": "methionine synthase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R00946", "R05182"], "ec-code": "2.1.1.13", "sbo": "SBO:0000176"}, "metabolites": {"thf_c": 1.0, "met-L_c": 1.0, "5mthf_c": -1.0, "hcys-L_c": -1.0, "h_c": 1.0}, "id": "RC00946", "gene_reaction_rule": "WBGene00010988 and WBGene00006510"}, {"subsystem": "One carbon pool by folate", "name": "10-formyltetrahydrofolate:NADP+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00941", "ec-code": "1.5.1.6", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "nadp_c": -1.0, "nadph_c": 1.0, "h_c": 1.0, "co2_c": 1.0, "10fthf_c": -1.0, "thf_c": 1.0}, "id": "RC00941", "gene_reaction_rule": "WBGene00000109"}, {"subsystem": "One carbon pool by folate", "name": "Formate:tetrahydrofolate ligase (ADP-forming)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00943", "ec-code": "6.3.4.3", "sbo": "SBO:0000176"}, "metabolites": {"for_c": -1.0, "atp_c": -1.0, "thf_c": -1.0, "adp_c": 1.0, "pi_c": 1.0, "10fthf_c": 1.0}, "id": "RC00943", "gene_reaction_rule": "WBGene00019492"}, {"subsystem": "Exchange with the environment", "name": "Bilirubin exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"bilirub_e": -1.0}, "id": "EX00486", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Adenine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"ade_c": 1.0, "ade_e": -1.0}, "id": "TCE0333", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Maltose transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"malt_c": 1.0, "malt_e": -1.0}, "id": "TCE0332", "gene_reaction_rule": ""}, {"subsystem": "Tyrosine metabolism", "name": "3,4-Dihydroxyphenylacetaldehyde:NADP+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R03302", "ec-code": "1.2.1.5", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "nadp_c": -1.0, "nadph_c": 1.0, "34dhpac_c": -1.0, "34dhpha_c": 1.0, "h_c": 2.0}, "id": "RC03302", "gene_reaction_rule": "WBGene00000111"}, {"subsystem": "Purine metabolism", "name": "5-Phosphoribosylformylglycinamide:L-glutamine amido-ligase (ADP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R04463", "ec-code": "6.3.5.3", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "atp_c": -1.0, "gln-L_c": -1.0, "glu-L_c": 1.0, "fgam_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "fpram_c": 1.0, "pi_c": 1.0}, "id": "RC04463", "gene_reaction_rule": "WBGene00008654"}, {"subsystem": "Tyrosine metabolism", "name": "3,4-Dihydroxyphenylacetaldehyde:NAD+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03300", "ec-code": "1.2.1.5", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "34dhpac_c": -1.0, "34dhpha_c": 1.0, "h_c": 2.0, "nad_c": -1.0, "nadh_c": 1.0}, "id": "RC03300", "gene_reaction_rule": "WBGene00000111"}, {"subsystem": "Transport", "name": "D-Galactose transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"gal_c": 1.0, "gal_e": -1.0}, "id": "TCE0338", "gene_reaction_rule": ""}, {"subsystem": "One carbon pool by folate", "name": "5,6,7,8-tetrahydrofolate:NADP+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00939", "ec-code": "1.5.1.3", "sbo": "SBO:0000176"}, "metabolites": {"thf_c": 1.0, "nadp_c": 1.0, "nadph_c": -1.0, "dhf_c": -1.0, "h_c": -1.0}, "id": "RC00939", "gene_reaction_rule": "WBGene00007974"}, {"subsystem": "Starch and sucrose metabolism", "name": "cellobiose glucohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00306", "ec-code": "3.2.1.21", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "glc-D_c": 2.0, "clb_c": -1.0}, "id": "RC00306", "gene_reaction_rule": "WBGene00016848 or WBGene00017103"}, {"subsystem": "Exchange with the environment", "name": "Platelet-activating factor exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"paf_e": -1.0}, "id": "EX04598", "gene_reaction_rule": ""}, {"subsystem": "Ether lipid metabolism", "name": "1-Acyl-glycerone-3-phosphate:long-chain-alcohol O-3-phospho-2-oxopropanyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R04311", "ec-code": "2.5.1.26", "sbo": "SBO:0000176"}, "metabolites": {"h_c": 1.0, "akdhap_c": 1.0, "Rtotal_c": 1.0, "alkylR1oh_c": -1.0, "adhap_c": -1.0}, "id": "RC04311", "gene_reaction_rule": "WBGene00000081"}, {"subsystem": "Aminoacyl-tRNA biosynthesis", "name": "L-Valine:tRNAVal ligase (AMP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03665", "ec-code": "6.1.1.9", "sbo": "SBO:0000176"}, "metabolites": {"valtrna_c": 1.0, "atp_c": -1.0, "val-L_c": -1.0, "ppi_c": 1.0, "amp_c": 1.0, "trnaval_c": -1.0}, "id": "RC03665", "gene_reaction_rule": "WBGene00006936"}, {"subsystem": "Carnitine biosynthesis", "name": "Protein lysine peptidase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R04313", "ec-code": "3.4.-.-", "sbo": "SBO:0000176"}, "metabolites": {"peptmelys_c": -1.0, "h2o_c": -1.0, "tmlys_c": 1.0, "pepX_c": 1.0}, "id": "RC04313", "gene_reaction_rule": ""}, {"subsystem": "Arginine and proline metabolism", "name": "trans-4-Hydroxy-L-proline:NADP+ 5-oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R03293", "ec-code": "1.5.1.2", "sbo": "SBO:0000176"}, "metabolites": {"1p3h5c_m": 1.0, "h_m": 2.0, "4hpro-LT_m": -1.0, "nadp_m": -1.0, "nadph_m": 1.0}, "id": "RM03293", "gene_reaction_rule": "WBGene00010924 or WBGene00018904"}, {"subsystem": "Arginine and proline metabolism", "name": "trans-4-Hydroxy-L-proline:NAD+ 5-oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R03291", "ec-code": "1.5.1.2", "sbo": "SBO:0000176"}, "metabolites": {"nad_m": -1.0, "1p3h5c_m": 1.0, "h_m": 2.0, "4hpro-LT_m": -1.0, "nadh_m": 1.0}, "id": "RM03291", "gene_reaction_rule": "WBGene00010924 or WBGene00018904"}, {"subsystem": "Fructose and mannose metabolism", "name": "ATP:6-deoxy-L-galactose 1-phosphotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03161", "ec-code": "2.7.1.52", "sbo": "SBO:0000176"}, "metabolites": {"fuc-L_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "atp_c": -1.0, "fuc1p-L_c": 1.0}, "id": "RC03161", "gene_reaction_rule": "WBGene00007745"}, {"subsystem": "Fatty acid elongation", "name": "trans-Tetradec-2-enoyl-CoA reductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03989", "ec-code": "1.3.1.38", "sbo": "SBO:0000176"}, "metabolites": {"tdcoa_m": 1.0, "td2coa_m": -1.0, "nadph_m": -1.0, "h_m": -1.0, "nadp_m": 1.0}, "id": "RM03989", "gene_reaction_rule": "WBGene00012375 or WBGene00012970"}, {"subsystem": "Aminoacyl-tRNA biosynthesis", "name": "L-Tryptophan -tRNA(Trp) ligase (AMP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03664", "ec-code": "6.1.1.2", "sbo": "SBO:0000176"}, "metabolites": {"atp_c": -1.0, "ppi_c": 1.0, "trnatrp_c": -1.0, "trp-L_c": -1.0, "amp_c": 1.0, "trptrna_c": 1.0}, "id": "RC03664", "gene_reaction_rule": "WBGene00006945"}, {"subsystem": "Carnitine biosynthesis", "name": "trimethyllysine dioxygenase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03451", "ec-code": "1.14.11.8", "sbo": "SBO:0000176"}, "metabolites": {"tmlys_m": -1.0, "3htmelys_m": 1.0, "akg_m": -1.0, "o2_m": -1.0, "co2_m": 1.0, "succ_m": 1.0}, "id": "RM03451", "gene_reaction_rule": "WBGene00001523"}, {"subsystem": "Fatty acid metabolism", "name": "fatty-acid--CoA ligase (fa17p0iso)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00390", "ec-code": "6.2.1.3", "sbo": "SBO:0000176"}, "metabolites": {"atp_c": -1.0, "ppi_c": 1.0, "fa17p0isocoa_c": 1.0, "coa_c": -1.0, "amp_c": 1.0, "fa17p0iso_c": -1.0}, "id": "RCC0102", "gene_reaction_rule": "WBGene00009221 or WBGene00020343 or WBGene00018152 or WBGene00013575 or WBGene00022037 or WBGene00019920 or WBGene00016716 or WBGene00011173"}, {"subsystem": "Peroxisomal fatty acid beta oxidation", "name": "Beta oxidation of fa17p0iso (peroxisomal)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R00388", "R02685", "R01778", "R00391"], "ec-code": ["1.3.3.6", "4.2.1.17", "1.1.1.211", "1.1.1.35", "2.3.1.16"], "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "h2o_c": -1.0, "nad_c": -1.0, "h2o2_c": 1.0, "fa15p0isocoa_c": 1.0, "fa17p0isocoa_c": -1.0, "coa_c": -1.0, "h_c": 1.0, "accoa_c": 1.0, "nadh_c": 1.0}, "id": "RCC0103", "gene_reaction_rule": "(WBGene00008167 or WBGene00008564 or WBGene00008565 or WBGene00008566 or WBGene00008567 or WBGene00019060 or WBGene00010336) and (WBGene00000991 or WBGene00017123) and WBGene00013284"}, {"subsystem": "Fatty acid metabolism", "name": "fatty-acid--CoA ligase (fa15p0iso)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00390", "ec-code": "6.2.1.3", "sbo": "SBO:0000176"}, "metabolites": {"atp_c": -1.0, "fa15p0iso_c": -1.0, "ppi_c": 1.0, "fa15p0isocoa_c": 1.0, "coa_c": -1.0, "amp_c": 1.0}, "id": "RCC0101", "gene_reaction_rule": "WBGene00009221 or WBGene00020343 or WBGene00018152 or WBGene00013575 or WBGene00022037 or WBGene00019920 or WBGene00016716 or WBGene00011173"}, {"subsystem": "Peroxisomal fatty acid beta oxidation", "name": "Beta oxidation of fa19c11 (peroxisomal)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R00388", "R02685", "R01778", "R00391"], "ec-code": ["1.3.3.6", "4.2.1.17", "1.1.1.211", "1.1.1.35", "2.3.1.16"], "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "h2o_c": -1.0, "nadh_c": 1.0, "nad_c": -1.0, "h2o2_c": 1.0, "fa17c9coa_c": 1.0, "coa_c": -1.0, "h_c": 1.0, "accoa_c": 1.0, "fa19c11coa_c": -1.0}, "id": "RCC0106", "gene_reaction_rule": "(WBGene00008167 or WBGene00008564 or WBGene00008565 or WBGene00008566 or WBGene00008567 or WBGene00019060 or WBGene00010336) and (WBGene00000991 or WBGene00017123) and WBGene00013284"}, {"subsystem": "Peroxisomal fatty acid beta oxidation", "name": "Beta oxidation of fa17c9 (peroxisomal)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R00388", "R02685", "R01778", "R00391"], "ec-code": ["1.3.3.6", "4.2.1.17", "1.1.1.211", "1.1.1.35", "2.3.1.16"], "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -3.0, "h2o_c": -3.0, "fa17c9coa_c": -1.0, "nad_c": -3.0, "fa11c3coa_c": 1.0, "h2o2_c": 3.0, "coa_c": -3.0, "h_c": 3.0, "accoa_c": 3.0, "nadh_c": 3.0}, "id": "RCC0107", "gene_reaction_rule": "(WBGene00008167 or WBGene00008564 or WBGene00008565 or WBGene00008566 or WBGene00008567 or WBGene00019060 or WBGene00010336) and (WBGene00000991 or WBGene00017123) and WBGene00013284"}, {"subsystem": "Peroxisomal fatty acid beta oxidation", "name": "Beta oxidation of fa15p0iso (peroxisomal)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R00388", "R02685", "R01778", "R00391"], "ec-code": ["1.3.3.6", "4.2.1.17", "1.1.1.211", "1.1.1.35", "2.3.1.16"], "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -3.0, "h2o_c": -3.0, "nad_c": -3.0, "fa15p0isocoa_c": -1.0, "h2o2_c": 3.0, "coa_c": -3.0, "h_c": 3.0, "accoa_c": 3.0, "fa9p0isocoa_c": 1.0, "nadh_c": 3.0}, "id": "RCC0104", "gene_reaction_rule": "(WBGene00008167 or WBGene00008564 or WBGene00008565 or WBGene00008566 or WBGene00008567 or WBGene00019060 or WBGene00010336) and (WBGene00000991 or WBGene00017123) and WBGene00013284"}, {"subsystem": "Terpenoid backbone biosynthesis", "name": "ATP:(R)-5-diphosphomevalonate carboxy-lyase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01121", "ec-code": "4.1.1.33", "sbo": "SBO:0000176"}, "metabolites": {"5dpmev_c": -1.0, "ipdp_c": 1.0, "atp_c": -1.0, "pi_c": 1.0, "adp_c": 1.0, "co2_c": 1.0}, "id": "RC01121", "gene_reaction_rule": "WBGene00012984"}, {"subsystem": "Cysteine and methionine metabolism", "name": "S-adenosylmethioninamine:putrescine 3-aminopropyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01920", "ec-code": "2.5.1.16", "sbo": "SBO:0000176"}, "metabolites": {"ametam_c": -1.0, "spmd_c": 1.0, "5mta_c": 1.0, "h_c": 1.0, "ptrc_c": -1.0}, "id": "RC01920", "gene_reaction_rule": "WBGene00012909"}, {"subsystem": "Carnitine shuttle", "name": "Acyl-CoA:L-carnitine O-acyltransferase I (vaccenyl CoA)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "2.3.1.21", "sbo": "SBO:0000176"}, "metabolites": {"crn_c": -1.0, "vacccrn_c": 1.0, "coa_c": 1.0, "vacccoa_c": -1.0}, "id": "RCC0108", "gene_reaction_rule": "WBGene00012907 or WBGene00021703 or WBGene00019644 or WBGene00008629 or WBGene00020911"}, {"subsystem": "Fatty acid metabolism", "name": "Palmitoyl-CoA:L-carnitine O-palmitoyltransferase I", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01923", "ec-code": "2.3.1.21", "sbo": "SBO:0000176"}, "metabolites": {"crn_c": -1.0, "pmtcoa_c": -1.0, "pmtcrn_c": 1.0, "coa_c": 1.0}, "id": "RC01923", "gene_reaction_rule": "WBGene00012907 or WBGene00021703 or WBGene00019644 or WBGene00008629 or WBGene00020911"}, {"subsystem": "Arginine and proline metabolism", "name": "L-erythro-4-hydroxyglutamate:2-oxoglutarate aminotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R05052", "ec-code": "2.6.1.1", "sbo": "SBO:0000176"}, "metabolites": {"akg_c": -1.0, "glu-L_c": 1.0, "e4hglu_c": -1.0, "4h2oglt_c": 1.0}, "id": "RC05052", "gene_reaction_rule": "WBGene00020146"}, {"subsystem": "Sphingolipid metabolism", "name": "sphingosine kinase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01926", "ec-code": "2.7.1.91", "sbo": "SBO:0000176"}, "metabolites": {"h_c": 1.0, "sphs1p_ce_c": 1.0, "sphings_ce_c": -1.0, "atp_c": -1.0, "adp_c": 1.0}, "id": "RC01926", "gene_reaction_rule": "WBGene00007918"}, {"subsystem": "Protein modification by hydroxylation", "name": "protein N-acetylglucosaminyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00417", "ec-code": "2.4.1.94", "sbo": "SBO:0000176"}, "metabolites": {"uacgam_c": -1.0, "pepasn_c": -1.0, "udp_c": 1.0, "h_c": 1.0, "pepasp_acgamam_c": 1.0}, "id": "RC00417", "gene_reaction_rule": ""}, {"subsystem": "Amino sugar and nucleotide sugar metabolism", "name": "UTP:N-acetyl-alpha-D-glucosamine-1-phosphate uridylyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00416", "ec-code": "2.7.7.23", "sbo": "SBO:0000176"}, "metabolites": {"uacgam_c": 1.0, "utp_c": -1.0, "ppi_c": 1.0, "acgam1p_c": -1.0, "h_c": -1.0}, "id": "RC00416", "gene_reaction_rule": "WBGene00007965"}, {"subsystem": "Purine metabolism", "name": "Inosine 5-monophosphate phosphohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01126", "ec-code": "3.1.3.5", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "pi_c": 1.0, "imp_c": -1.0, "ins_c": 1.0}, "id": "RC01126", "gene_reaction_rule": "WBGene00017775 or WBGene00012423 or WBGene00022201"}, {"subsystem": "One carbon pool by folate", "name": "S-Aminomethyldihydrolipoylprotein:(6S)-tetrahydrofolate aminomethyltransferase (ammonia-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02300", "ec-code": "2.1.2.10", "sbo": "SBO:0000176"}, "metabolites": {"h_m": 1.0, "methf_m": -1.0, "h2o_m": -1.0, "5fthf_m": 1.0}, "id": "RM02300", "gene_reaction_rule": "WBGene00017765"}, {"subsystem": "Alanine, aspartate and glutamate metabolism", "name": "L-Glutamate:NAD+ oxidoreductase (transaminating)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00093", "ec-code": "1.4.1.14", "sbo": "SBO:0000176"}, "metabolites": {"akg_c": -1.0, "gln-L_c": -1.0, "glu-L_c": 2.0, "h_c": -1.0, "nad_c": 1.0, "nadh_c": -1.0}, "id": "RC00093", "gene_reaction_rule": "WBGene00012326"}, {"subsystem": "Fatty acid metabolism", "name": "fa19c11 drain", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"fa19c11_c": -1.0}, "id": "DMN0032", "gene_reaction_rule": ""}, {"subsystem": "Fatty acid metabolism", "name": "fa17c9 drain", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"fa17c9_c": -1.0}, "id": "DMN0031", "gene_reaction_rule": ""}, {"subsystem": "Fatty acid metabolism", "name": "fa16p1n7 drain", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"fa16p1n7_c": -1.0}, "id": "DMN0030", "gene_reaction_rule": ""}, {"subsystem": "Ascaroside biosynthesis", "name": "ascr5 synthesis", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"o2_c": -12.0, "h2o_c": -12.0, "accoa_c": 12.0, "ascr5coa_c": 1.0, "27ascfa27p0coa_c": -1.0, "h2o2_c": 12.0, "coa_c": -12.0, "h_c": 12.0, "nad_c": -12.0, "nadh_c": 12.0}, "id": "RCC0213", "gene_reaction_rule": "(WBGene00008564 or WBGene00008565) and WBGene00017123 and WBGene00000991 and WBGene00013284"}, {"subsystem": "Cysteine and methionine metabolism", "name": "spermine demand", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"sprm_c": -1.0}, "id": "DMN0035", "gene_reaction_rule": ""}, {"subsystem": "Cysteine and methionine metabolism", "name": "spermidine demand", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"spmd_c": -1.0}, "id": "DMN0034", "gene_reaction_rule": ""}, {"subsystem": "Ubiquinone and other terpenoid-quinone biosynthesis", "name": "ubiquinone demand", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"q_m": -1.0}, "id": "DMN0039", "gene_reaction_rule": ""}, {"subsystem": "Miscellaneous", "name": "vitamin C demand", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"ascb-L_c": -1.0}, "id": "DMN0038", "gene_reaction_rule": ""}, {"subsystem": "Ascaroside biosynthesis", "name": "ascr18 synthesis", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"o2_c": -8.0, "h2o_c": -8.0, "accoa_c": 8.0, "26ascfa27p0coa_c": -1.0, "ascr18coa_c": 1.0, "h2o2_c": 8.0, "coa_c": -8.0, "h_c": 8.0, "nad_c": -8.0, "nadh_c": 8.0}, "id": "RCC0218", "gene_reaction_rule": "(WBGene00008564 or WBGene00019060) and WBGene00017123 and WBGene00000991 and WBGene00013284"}, {"subsystem": "Ascaroside biosynthesis", "name": "ascr7 synthesis", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"h2o2_c": 1.0, "o2_c": -1.0, "ascr1coa_c": -1.0, "ascr7coa_c": 1.0}, "id": "RCC0219", "gene_reaction_rule": "WBGene00008564 or WBGene00008566"}, {"subsystem": "Purine metabolism", "name": "2-Deoxyguanosine 5-triphosphate diphosphohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01855", "ec-code": "3.6.1.19", "sbo": "SBO:0000176"}, "metabolites": {"ppi_c": 1.0, "h2o_c": -1.0, "dgtp_c": -1.0, "dgmp_c": 1.0, "h_c": 1.0}, "id": "RC01855", "gene_reaction_rule": "WBGene00001823"}, {"subsystem": "Glycerophospholipid metabolism", "name": "CDP-choline:1,2-diacyl-sn-glycerol cholinephosphotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01321", "ec-code": "2.7.8.2", "sbo": "SBO:0000176"}, "metabolites": {"dag_pl_c": -1.0, "pchol_c": 1.0, "cdpchol_c": -1.0, "h_c": 1.0, "cmp_c": 1.0}, "id": "RC01321", "gene_reaction_rule": "WBGene00013024"}, {"subsystem": "Fructose and mannose metabolism", "name": "ATP:D-mannose 6-phosphotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01326", "ec-code": "2.7.1.1", "sbo": "SBO:0000176"}, "metabolites": {"h_c": 1.0, "man6p_c": 1.0, "adp_c": 1.0, "atp_c": -1.0, "man_c": -1.0}, "id": "RC01326", "gene_reaction_rule": "WBGene00008780 or WBGene00010416 or WBGene00022306"}, {"subsystem": "Exchange with the environment", "name": "H2O exchange", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"h2o_e": -1.0}, "id": "EX00001", "gene_reaction_rule": ""}, {"subsystem": "Arachidonic acid metabolism", "name": "Prostaglandin G/H synthase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R01590", "R00073"], "ec-code": "1.14.99.1", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -2.0, "h2o_c": 1.0, "nadp_c": 1.0, "nadph_c": -1.0, "prostgh2_c": 1.0, "h_c": -1.0, "arachd_c": -1.0}, "id": "RCC0078", "gene_reaction_rule": ""}, {"subsystem": "Glycerolipid metabolism", "name": "acyl-CoA:sn-glycerol-3-phosphate 1-O-acyltransferase (acting on Rtotal4 group)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00851", "ec-code": "2.3.1.15", "sbo": "SBO:0000176"}, "metabolites": {"Rtotal4coa_c": -1.0, "glyc3p_c": -1.0, "coa_c": 1.0, "alpa_tag_c": 1.0}, "id": "RCC0079", "gene_reaction_rule": "WBGene00017261 or (WBGene00018657 or WBGene00011106)"}, {"subsystem": "Iron metabolism", "name": "heme protein synthesis", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"apohemeprotein_c": -1.0, "pheme_c": -1.0, "hemeprotein_c": 1.0}, "id": "RCC0076", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "phosphatidylglycerol  exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"pglyc_e": -1.0}, "id": "EX00344", "gene_reaction_rule": ""}, {"subsystem": "Taurine and hypotaurine metabolism", "name": "sulfinic acid oxidation", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"Lcyst_c": 1.0, "h2o2_c": -1.0, "h2o_c": 1.0, "h_c": -1.0, "3sala_c": -1.0}, "id": "RCC0074", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Ethanolamine phosphate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"ethamp_e": -1.0}, "id": "EX00346", "gene_reaction_rule": ""}, {"subsystem": "Monomethyl branched chain fatty acid synthesis", "name": "long chain fatty acid elongation (C13:iso to C15:iso)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R09419", "R10826", "R10827", "R10828"], "ec-code": ["2.3.1.199", "1.1.1.330", "4.2.1.134", "1.3.1.93"], "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": 1.0, "malcoa_c": -1.0, "nadph_c": -2.0, "fa15p0iso_c": 1.0, "nadp_c": 2.0, "coa_c": 1.0, "h_c": -3.0, "co2_c": 1.0, "fa13p0iso_c": -1.0}, "id": "RCC0072", "gene_reaction_rule": "WBGene00001243 and WBGene00002891 and WBGene00020517 and WBGene00000198"}, {"subsystem": "Monomethyl branched chain fatty acid synthesis", "name": "long chain fatty acid elongation (C15:iso to C17:iso)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R09419", "R10826", "R10827", "R10828"], "ec-code": ["2.3.1.199", "1.1.1.330", "4.2.1.134", "1.3.1.93"], "sbo": "SBO:0000176"}, "metabolites": {"co2_c": 1.0, "h2o_c": 1.0, "malcoa_c": -1.0, "nadph_c": -2.0, "fa15p0iso_c": -1.0, "nadp_c": 2.0, "coa_c": 1.0, "h_c": -3.0, "fa17p0iso_c": 1.0}, "id": "RCC0073", "gene_reaction_rule": "(WBGene00001243 or WBGene00001244) and WBGene00002891 and WBGene00020517 and WBGene00000198"}, {"subsystem": "Biosynthesis of unsaturated fatty acids", "name": "long chain fatty acid elongation (Palmitoleyl-coA to Vaccenyl-coA)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R09419", "R10826", "R10827", "R10828"], "ec-code": ["2.3.1.199", "1.1.1.330", "4.2.1.134", "1.3.1.93"], "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": 1.0, "malcoa_c": -1.0, "nadph_c": -2.0, "vacccoa_c": 1.0, "nadp_c": 2.0, "coa_c": 1.0, "h_c": -3.0, "fa16p1n7coa_c": -1.0, "co2_c": 1.0}, "id": "RCC0070", "gene_reaction_rule": "(WBGene00001239 or WBGene00001240 or WBGene00001241 or WBGene00001242 or WBGene00001243 or WBGene00001244 or WBGene00001245 or WBGene00001247) and WBGene00002891 and WBGene00020517 and WBGene00000198"}, {"subsystem": "Monomethyl branched chain fatty acid synthesis", "name": "branched-chain fatty acid synthase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "2.3.1.85", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": 3.0, "malcoa_c": -4.0, "nadph_c": -8.0, "ivcoa_c": -1.0, "nadp_c": 8.0, "coa_c": 5.0, "h_c": -11.0, "co2_c": 4.0, "fa13p0iso_c": 1.0}, "id": "RCC0071", "gene_reaction_rule": "WBGene00009342"}, {"subsystem": "Purine metabolism", "name": "ATP:sulfate adenylyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00529", "ec-code": "2.7.7.4", "sbo": "SBO:0000176"}, "metabolites": {"so4_c": -1.0, "ppi_c": 1.0, "h_c": -1.0, "atp_c": -1.0, "aps_c": 1.0}, "id": "RC00529", "gene_reaction_rule": "WBGene00004091"}, {"subsystem": "Transport", "name": "Aminoacetone transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"aact_m": -1.0, "aact_c": 1.0}, "id": "TCM0144", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "2-Oxobutanoate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"2obut_c": 1.0, "2obut_e": -1.0}, "id": "TCE5365", "gene_reaction_rule": ""}, {"subsystem": "Methane metabolism", "name": "S-Formylglutathione hydrolase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00527", "ec-code": "3.1.2.12", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "gthrd_c": 1.0, "Sfglutth_c": -1.0, "for_c": 1.0, "h_c": 1.0}, "id": "RC00527", "gene_reaction_rule": "WBGene00013018"}, {"subsystem": "Histidine metabolism", "name": "N-formylglutamate deformylase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00525", "ec-code": "3.5.1.68", "sbo": "SBO:0000176"}, "metabolites": {"glu-L_c": 1.0, "h2o_c": -1.0, "Nforglu_c": -1.0, "h_c": 2.0, "for_c": 1.0}, "id": "RC00525", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "taurocholic acid transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"tchola_c": 1.0, "tchola_e": -1.0}, "id": "TCE0795", "gene_reaction_rule": ""}, {"subsystem": "Bacterial digestion", "name": "Bacterial outer LPS (except for the first two monomers embedded in lipa) degradation", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -10.0, "etha_c": 2.0, "glc-D-A_c": 9.0, "h_c": -4.0, "nad_c": 2.0, "nadh_c": -2.0, "pyr_c": 1.0, "outerlps_BAC_c": -1.0}, "id": "DGR0017", "gene_reaction_rule": ""}, {"subsystem": "Bacterial digestion", "name": "Bacterial lipa (inner LPS and first two monomers of outer section) degradation", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -5.0, "nadh_c": -4.0, "ddca_c": 1.0, "pyr_c": 2.0, "gam_c": 2.0, "nad_c": 4.0, "r5p_c": 2.0, "lipa_BAC_c": -1.0, "ttdca_c": 5.0}, "id": "DGR0016", "gene_reaction_rule": ""}, {"subsystem": "Bacterial digestion", "name": "Bacterial outer LPS (except for the first two monomers embedded in lipa) uptake", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"outerlps_BAC_e": -1.0, "outerlps_BAC_c": 1.0}, "id": "DGR0015", "gene_reaction_rule": ""}, {"subsystem": "Bacterial digestion", "name": "Bacterial lipa (inner LPS and first two monomers of outer section) uptake", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"lipa_BAC_c": 1.0, "lipa_BAC_e": -1.0}, "id": "DGR0014", "gene_reaction_rule": ""}, {"subsystem": "Bacterial digestion", "name": "Bacterial LPS degradation into lipa (inner LPS plus first two outer monomers) and outerlps_BAC (the rest of LPS)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"outerlps_BAC_e": 1.0, "lps_BAC_e": -1.0, "lipa_BAC_e": 1.0}, "id": "DGR0013", "gene_reaction_rule": ""}, {"subsystem": "Bacterial digestion", "name": "Bacterial peptidoglycan degradation", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"acgam_c": 2.0, "h2o_c": -8.0, "peptido_BAC_c": -1.0, "glu-L_c": 1.0, "ala-L_c": 3.0, "lac-D_c": 1.0, "lys-L_c": 1.0, "h_c": -1.0, "co2_c": 1.0}, "id": "DGR0012", "gene_reaction_rule": ""}, {"subsystem": "Bacterial digestion", "name": "Bacterial peptidoglycan uptake", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"peptido_BAC_e": -1.0, "peptido_BAC_c": 1.0}, "id": "DGR0011", "gene_reaction_rule": ""}, {"subsystem": "Bacterial digestion", "name": "Bacterial DNA uptake", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dna_BAC_c": 1.0, "dna_BAC_e": -1.0}, "id": "DGR0010", "gene_reaction_rule": ""}, {"subsystem": "N-Glycan biosynthesis", "name": "dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase (6man to 7man)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R06259", "ec-code": "2.4.1.259", "sbo": "SBO:0000176"}, "metabolites": {"m5mpdol_c": -1.0, "dolp_c": 1.0, "m6mpdol_c": 1.0, "h_c": 1.0, "dolmanp_c": -1.0}, "id": "RC06259", "gene_reaction_rule": "WBGene00007556"}, {"subsystem": "N-Glycan biosynthesis", "name": "dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase (5man to 6man)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R06258", "ec-code": "2.4.1.258", "sbo": "SBO:0000176"}, "metabolites": {"m5mpdol_c": 1.0, "dolp_c": 1.0, "m4mpdol_c": -1.0, "dolmanp_c": -1.0, "h_c": 1.0}, "id": "RC06258", "gene_reaction_rule": "WBGene00010720"}, {"subsystem": "Bacterial digestion", "name": "Bacterial phosphatidylethanolamine degradation", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02053", "ec-code": "3.1.1.4", "sbo": "SBO:0000176"}, "metabolites": {"Rtotal_BAC_c": 2.0, "h2o_c": -2.0, "pe_BAC_c": -1.0, "h_c": 2.0, "g3pe_c": 1.0}, "id": "DGR0019", "gene_reaction_rule": "WBGene00019747 or WBGene00009801 or WBGene00012319 or WBGene00017026 or WBGene00019229 or WBGene00022233 or WBGene00011423 or WBGene00007419 or WBGene00044468"}, {"subsystem": "Bacterial digestion", "name": "Bacterial phosphatidylethanolamine uptake", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"pe_BAC_e": -1.0, "pe_BAC_c": 1.0}, "id": "DGR0018", "gene_reaction_rule": ""}, {"subsystem": "One carbon pool by folate", "name": "5,10-methylenetetrahydrofolate:NAD+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01218", "ec-code": "1.5.1.15", "sbo": "SBO:0000176"}, "metabolites": {"nadh_c": 1.0, "nad_c": -1.0, "mlthf_c": -1.0, "methf_c": 1.0}, "id": "RC01218", "gene_reaction_rule": "WBGene00000929"}, {"subsystem": "Transport", "name": "testosterone transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"tststerone_e": 1.0, "tststerone_c": -1.0}, "id": "TCE6001", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "N-acetylgalactosamine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"acgal_c": -1.0, "acgal_e": 1.0}, "id": "TCE6002", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Thiosulfate and L-Malate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"mal-L_c": -1.0, "tsul_m": -1.0, "tsul_c": 1.0, "mal-L_m": 1.0}, "id": "TCM0212", "gene_reaction_rule": ""}, {"subsystem": "Pyruvate metabolism", "name": "(S)-Malate:NADP+ oxidoreductase(oxaloacetate-decarboxylating)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00216", "ec-code": "1.1.1.40", "sbo": "SBO:0000176"}, "metabolites": {"nadph_m": 1.0, "pyr_m": 1.0, "nadp_m": -1.0, "mal-L_m": -1.0, "co2_m": 1.0}, "id": "RM00216", "gene_reaction_rule": "WBGene00012983"}, {"subsystem": "Transport", "name": "Octanoyl-CoA (n-C8:0CoA) transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"occoa_m": 1.0, "occoa_c": -1.0}, "id": "TCM0210", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "dATP and ATP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"atp_m": -1.0, "datp_c": -1.0, "atp_c": 1.0, "datp_m": 1.0}, "id": "TCM0216", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Sulfite and L-Malate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"mal-L_c": -1.0, "so3_c": 1.0, "so3_m": -1.0, "mal-L_m": 1.0}, "id": "TCM0217", "gene_reaction_rule": ""}, {"subsystem": "Degradation of alkylacylglycerolipids", "name": "aldehyde:NAD+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00631", "ec-code": "1.2.1.3", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "fattyald_c": -1.0, "h_c": 2.0, "nad_c": -1.0, "nadh_c": 1.0, "Rtotal7_c": 1.0}, "id": "RC00631", "gene_reaction_rule": "(WBGene00000108 or WBGene00000110) or (WBGene00000117 or WBGene00000118)"}, {"subsystem": "Transport", "name": "dADP and ADP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"adp_m": -1.0, "dadp_c": -1.0, "adp_c": 1.0, "dadp_m": 1.0}, "id": "TCM0215", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "dGDP and dATP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"datp_c": -1.0, "dgdp_c": 1.0, "dgdp_m": -1.0, "datp_m": 1.0}, "id": "TCM0218", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "dTDP and dATP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"datp_c": -1.0, "dtdp_m": -1.0, "dtdp_c": 1.0, "datp_m": 1.0}, "id": "TCM0219", "gene_reaction_rule": ""}, {"subsystem": "Arginine and proline metabolism", "name": "N4-Acetylaminobutanal:NAD+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R05050", "ec-code": "1.2.1.3", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "n4abutn_c": -1.0, "h_c": 2.0, "nad_c": -1.0, "nadh_c": 1.0, "4aabutn_c": 1.0}, "id": "RC05050", "gene_reaction_rule": "(WBGene00000108 or WBGene00000110) or (WBGene00000117 or WBGene00000118)"}, {"subsystem": "Exchange with the environment", "name": "Orotate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"orot_e": -1.0}, "id": "EX00295", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Inosine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"ins_e": -1.0}, "id": "EX00294", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "D-Glyceraldehyde exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"glyald_e": -1.0}, "id": "EX00577", "gene_reaction_rule": ""}, {"subsystem": "Biomass assembly", "name": "Assembly of biomass (without DNA or collagen)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000629"}, "metabolites": {"tag_c": -0.117468, "Biomass_c": 1.0, "RNA_c": -0.188823, "PhosphoL_c": -0.129849, "prot_mito_m": -1.152647, "biomass_minor_c": -0.0001, "prot_other_c": -4.604242, "tre_c": -0.029368, "glycogen_c": -0.204599, "Glycans_c": -0.058654}, "id": "BIO0104", "gene_reaction_rule": ""}, {"subsystem": "Biomass assembly", "name": "Assembly of biomass (without storage or collagen)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000629"}, "metabolites": {"Biomass_c": 1.0, "RNA_c": -0.221119, "PhosphoL_c": -0.152058, "prot_mito_m": -1.349791, "biomass_minor_c": -0.0001, "prot_other_c": -5.391734, "DNA_c": -0.019129, "Glycans_c": -0.068686}, "id": "BIO0105", "gene_reaction_rule": ""}, {"subsystem": "Biomass assembly", "name": "Assembly of biomass (without DNA, storage, or collagen)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000629"}, "metabolites": {"Biomass_c": 1.0, "RNA_c": -0.222489, "PhosphoL_c": -0.153, "prot_mito_m": -1.358154, "biomass_minor_c": -0.0001, "prot_other_c": -5.42514, "Glycans_c": -0.069111}, "id": "BIO0106", "gene_reaction_rule": ""}, {"subsystem": "Biomass assembly", "name": "Assembly of biomass (all components included)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000629"}, "metabolites": {"tag_c": -0.116853, "Biomass_c": 1.0, "RNA_c": -0.187835, "PhosphoL_c": -0.129169, "prot_mito_m": -1.146612, "biomass_minor_c": -0.0001, "prot_other_c": -4.007619, "tre_c": -0.029215, "collg_c": -0.201448, "glycogen_c": -0.203528, "DNA_c": -0.016249, "Glycans_c": -0.058347}, "id": "BIO0107", "gene_reaction_rule": ""}, {"subsystem": "Biomass assembly", "name": "Assembly of biomass (without DNA)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000629"}, "metabolites": {"tag_c": -0.117468, "Biomass_c": 1.0, "RNA_c": -0.188823, "PhosphoL_c": -0.129849, "prot_mito_m": -1.152647, "biomass_minor_c": -0.0001, "prot_other_c": -4.028712, "tre_c": -0.029368, "collg_c": -0.202508, "glycogen_c": -0.204599, "Glycans_c": -0.058654}, "id": "BIO0100", "gene_reaction_rule": ""}, {"subsystem": "Biomass assembly", "name": "Assembly of biomass (without DNA or storage)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000629"}, "metabolites": {"Biomass_c": 1.0, "RNA_c": -0.222489, "PhosphoL_c": -0.153, "prot_mito_m": -1.358154, "biomass_minor_c": -0.0001, "prot_other_c": -4.746997, "collg_c": -0.238613, "Glycans_c": -0.069111}, "id": "BIO0101", "gene_reaction_rule": ""}, {"subsystem": "Biomass assembly", "name": "Assembly of biomass (without collagen)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000629"}, "metabolites": {"tag_c": -0.116853, "Biomass_c": 1.0, "RNA_c": -0.187835, "PhosphoL_c": -0.129169, "prot_mito_m": -1.146612, "biomass_minor_c": -0.0001, "prot_other_c": -4.580136, "tre_c": -0.029215, "glycogen_c": -0.203528, "DNA_c": -0.016249, "Glycans_c": -0.058347}, "id": "BIO0102", "gene_reaction_rule": ""}, {"subsystem": "Biomass assembly", "name": "Assembly of biomass (without storage)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000629"}, "metabolites": {"Biomass_c": 1.0, "RNA_c": -0.221119, "PhosphoL_c": -0.152058, "prot_mito_m": -1.349791, "biomass_minor_c": -0.0001, "prot_other_c": -4.717767, "collg_c": -0.237144, "DNA_c": -0.019129, "Glycans_c": -0.068686}, "id": "BIO0103", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "D-Galactose exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"gal_e": -1.0}, "id": "EX00124", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Oxidized glutathione exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"gthox_e": -1.0}, "id": "EX00127", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "D-Ribose exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"rib-D_e": -1.0}, "id": "EX00121", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "L-Leucine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"leu-L_e": -1.0}, "id": "EX00123", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Fumarate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"fum_e": -1.0}, "id": "EX00122", "gene_reaction_rule": ""}, {"subsystem": "Glycine, serine and threonine metabolism", "name": "Acetyl-CoA:glycine C-acetyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00371", "ec-code": "2.3.1.29", "sbo": "SBO:0000176"}, "metabolites": {"accoa_m": -1.0, "2aobut_m": 1.0, "coa_m": 1.0, "gly_m": -1.0}, "id": "RM00371", "gene_reaction_rule": "WBGene00012007"}, {"subsystem": "Exchange with the environment", "name": "\"5,6-Dihydrothymine\" exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"56dthm_e": -1.0}, "id": "EX00906", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Phosphatidylcholine transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"pchol_c": 1.0, "h2o_c": -1.0, "atp_c": -1.0, "pchol_m": -1.0, "h_c": 1.0, "adp_c": 1.0, "pi_c": 1.0}, "id": "TCM0108", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "2-Oxoglutarate and L-Malate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"mal-L_c": -1.0, "akg_c": 1.0, "mal-L_m": 1.0, "akg_m": -1.0}, "id": "TCM0109", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Glycine betaine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"glyb_m": -1.0, "glyb_c": 1.0}, "id": "TCM0106", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Thiamin transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"thm_c": -1.0, "thm_m": 1.0}, "id": "TCM0107", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Succinate and Phosphate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"succ_c": -1.0, "pi_c": 1.0, "succ_m": 1.0, "pi_m": -1.0}, "id": "TCM0104", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "dTDP and dGDP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dtdp_m": 1.0, "dgdp_c": 1.0, "dtdp_c": -1.0, "dgdp_m": -1.0}, "id": "TCM0105", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "dUDP and dADP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dadp_c": -1.0, "dudp_m": -1.0, "dudp_c": 1.0, "dadp_m": 1.0}, "id": "TCM0101", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "cAMP exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"camp_e": -1.0}, "id": "EX00575", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Bilirubin beta-diglucuronide and Bicarbonate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"hco3_c": -1.0, "hco3_e": 1.0, "bildglcur_c": 1.0, "bildglcur_e": -1.0}, "id": "TCE0658", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Adenosine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"adn_e": -1.0}, "id": "EX00212", "gene_reaction_rule": ""}, {"subsystem": "Biosynthesis of unsaturated fatty acids", "name": "steroyl-CoA,hydrogen-donor:oxygen oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02222", "ec-code": "1.14.19.1", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "h2o_c": 2.0, "odecoa_c": 1.0, "ficytb_c": 2.0, "stcoa_c": -1.0, "focytb_c": -2.0}, "id": "RC02222", "gene_reaction_rule": "WBGene00001399 or WBGene00001398"}, {"subsystem": "Exchange with the environment", "name": "D-Glycerate 2-phosphate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"2pg_e": -1.0}, "id": "EX00631", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "3-Hydroxyanthranilate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"3hanthrn_e": -1.0}, "id": "EX00632", "gene_reaction_rule": ""}, {"subsystem": "Terpenoid backbone biosynthesis", "name": " prenyl protein peptidase; Ste24 endopeptidase (acting on farnesyl moiety)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R09845", "ec-code": ["3.4.24.84", "3.4.22.-"], "sbo": "SBO:0000176"}, "metabolites": {"protSfar_c": -1.0, "h2o_c": -1.0, "pepd_c": 1.0, "protSfarC_c": 1.0}, "id": "RC09845", "gene_reaction_rule": "WBGene00001405 or WBGene00001406"}, {"subsystem": "Terpenoid backbone biosynthesis", "name": "farnesyl-diphosphate:protein-cysteine farnesyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R09844", "ec-code": "2.5.1.58", "sbo": "SBO:0000176"}, "metabolites": {"protCys_c": -1.0, "ppi_c": 1.0, "frdp_c": -1.0, "protSfar_c": 1.0}, "id": "RC09844", "gene_reaction_rule": "WBGene00006465 and WBGene00019823"}, {"subsystem": "Transport", "name": "Reduced glutathione transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"gthrd_e": 1.0, "gthrd_c": -1.0}, "id": "TCE5376", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Procollagen 5-hydroxy-L-lysine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"pcollg5hlys_e": 1.0, "pcollg5hlys_c": -1.0}, "id": "TCE5377", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Formaldehyde transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"fald_e": -1.0, "fald_c": 1.0}, "id": "TCE5374", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "ATP transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"atp_e": 1.0, "atp_c": -1.0}, "id": "TCE5375", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Ethanolamine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"etha_e": -1.0, "etha_c": 1.0}, "id": "TCE5372", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Fe3+ transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"fe3_c": -1.0, "fe3_e": 1.0}, "id": "TCE5373", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Aminoacetone transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"aact_e": -1.0, "aact_c": 1.0}, "id": "TCE5370", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Glyoxylate transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"glx_e": 1.0, "glx_c": -1.0}, "id": "TCE5371", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "galactosyl glucosyl ceramide transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"galgluside_ce_c": -1.0, "galgluside_ce_e": 1.0}, "id": "TCE5378", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Phosphatidylinositol secretion", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"pail_e": 1.0, "pail_c": -1.0}, "id": "TCE5379", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Deoxyguanosine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dgsn_c": 1.0, "dgsn_e": -1.0}, "id": "TCE0788", "gene_reaction_rule": ""}, {"subsystem": "Valine, leucine and isoleucine degradation", "name": "L-3-amino-isobutanoate:2-oxoglutarate aminotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R04188", "ec-code": "2.6.1.22", "sbo": "SBO:0000176"}, "metabolites": {"2mop_m": -1.0, "akg_m": 1.0, "glu-L_m": -1.0, "3aib_m": 1.0}, "id": "RM04188", "gene_reaction_rule": "WBGene00001794"}, {"subsystem": "Transport", "name": "L-Arabinose transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"arab-L_e": -1.0, "arab-L_c": 1.0}, "id": "TCE1309", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Glycerol transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"glyc_e": 1.0, "glyc_c": -1.0}, "id": "TCE1308", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "L-Carnitine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"crn_c": 1.0, "crn_e": -1.0}, "id": "TCE1307", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Glycine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"gly_e": -1.0, "gly_c": 1.0}, "id": "TCE1306", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Xylitol transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"xylt_c": 1.0, "xylt_e": -1.0}, "id": "TCE1305", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "L-Lactate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"lac-L_c": 1.0, "lac-L_e": -1.0}, "id": "TCE1304", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "L-Proline transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"pro-L_c": 1.0, "pro-L_e": -1.0}, "id": "TCE1303", "gene_reaction_rule": ""}, {"subsystem": "Pyruvate metabolism", "name": "ATP:pyruvate,water phosphotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00199", "ec-code": "2.7.9.2", "sbo": "SBO:0000176"}, "metabolites": {"h_m": 2.0, "pyr_m": -1.0, "atp_m": -1.0, "h2o_m": -1.0, "pi_m": 1.0, "amp_m": 1.0, "pep_m": 1.0}, "id": "RM00199", "gene_reaction_rule": "WBGene00011893"}, {"subsystem": "Transport", "name": "O2 transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"o2_c": 1.0, "o2_e": -1.0}, "id": "TCE1301", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Ethanol transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"etoh_e": -1.0, "etoh_c": 1.0}, "id": "TCE1300", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "3-Hydroxy-2-methylpropanoate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"3hmp_e": -1.0}, "id": "EX06001", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "sedoheptulose exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"sedh_e": -1.0}, "id": "EX02076", "gene_reaction_rule": ""}, {"subsystem": "Tryptophan metabolism", "name": "Tryptamine:oxygen oxidoreductase (deaminating)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02173", "ec-code": "1.4.3.4", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "h2o_c": -1.0, "h2o2_c": 1.0, "trypta_c": -1.0, "nh4_c": 1.0, "id3acald_c": 1.0}, "id": "RC02173", "gene_reaction_rule": "WBGene00000138"}, {"subsystem": "Pyrimidine metabolism", "name": "deoxyuridine:orthophosphate 2-deoxy-D-ribosyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R02484", "ec-code": ["2.4.2.1", "2.4.2.3"], "sbo": "SBO:0000176"}, "metabolites": {"ura_c": 1.0, "2dr1p_c": 1.0, "pi_c": -1.0, "duri_c": -1.0}, "id": "RC02484", "gene_reaction_rule": "WBGene00019298 or WBGene00022817"}, {"subsystem": "Pyrimidine metabolism", "name": "Deoxycytidine aminohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02485", "ec-code": "3.5.4.5", "sbo": "SBO:0000176"}, "metabolites": {"dcyt_c": -1.0, "h2o_c": -1.0, "h_c": -1.0, "duri_c": 1.0, "nh4_c": 1.0}, "id": "RC02485", "gene_reaction_rule": "WBGene00000391 or WBGene00000392"}, {"subsystem": "Transport", "name": "Pyridoxine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"pydxn_c": 1.0, "pydxn_e": -1.0}, "id": "TCE0430", "gene_reaction_rule": ""}, {"subsystem": "Primary bile acid biosynthesis", "name": "cholesterol 26-hydroxylase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R08505", "ec-code": "1.14.13.15", "sbo": "SBO:0000176"}, "metabolites": {"chsterol_m": -1.0, "h2o_m": 1.0, "nadp_m": 1.0, "o2_m": -1.0, "xol27oh_m": 1.0, "h_m": -1.0, "nadph_m": -1.0}, "id": "RM08505", "gene_reaction_rule": "WBGene00000905"}, {"subsystem": "Carnitine shuttle", "name": "Acyl-CoA:L-carnitine O-acyltransferase II (Dodecanoyl-CoA )", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "2.3.1.21", "sbo": "SBO:0000176"}, "metabolites": {"coa_m": -1.0, "ddcrn_m": -1.0, "ddcacoa_m": 1.0, "crn_m": 1.0}, "id": "RMC0058", "gene_reaction_rule": "WBGene00011122"}, {"subsystem": "Sulfur metabolism", "name": "Sulfite:ferricytochrome-c oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "1.8.3.1", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "so3_c": -1.0, "ficytC_m": -2.0, "so4_c": 1.0, "h_c": 2.0, "focytC_m": 2.0}, "id": "RMC0054", "gene_reaction_rule": "WBGene00010397 and (WBGene00017121 or WBGene00013854)"}, {"subsystem": "Pantothenate and CoA biosynthesis", "name": "ATP:pantothenate 4-phosphotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03018", "ec-code": "2.7.1.33", "sbo": "SBO:0000176"}, "metabolites": {"4ppan_c": 1.0, "pnto-R_c": -1.0, "adp_c": 1.0, "atp_c": -1.0, "h_c": 1.0}, "id": "RC03018", "gene_reaction_rule": "WBGene00004068 or WBGene00006862"}, {"subsystem": "Terpenoid backbone biosynthesis", "name": "Geranyl-diphosphate:isopentenyl-diphosphate geranyltrans-transferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02003", "ec-code": "2.5.1.10", "sbo": "SBO:0000176"}, "metabolites": {"ppi_c": 1.0, "ipdp_c": -1.0, "frdp_c": 1.0, "grdp_c": -1.0}, "id": "RC02003", "gene_reaction_rule": "WBGene00011058"}, {"subsystem": "Fatty acid elongation", "name": "Decanoyl-CoA:acetyl-CoA C-acyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R04742", "ec-code": "2.3.1.16", "sbo": "SBO:0000176"}, "metabolites": {"accoa_m": 1.0, "coa_m": -1.0, "dcacoa_m": 1.0, "3oddcoa_m": -1.0}, "id": "RM04742", "gene_reaction_rule": "WBGene00015125 or WBGene00009952"}, {"subsystem": "Purine metabolism", "name": "Deoxyadenosine aminohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02556", "ec-code": "3.5.4.4", "sbo": "SBO:0000176"}, "metabolites": {"din_c": 1.0, "h2o_c": -1.0, "dad-2_c": -1.0, "h_c": -1.0, "nh4_c": 1.0}, "id": "RC02556", "gene_reaction_rule": "WBGene00015551 or WBGene00016632"}, {"subsystem": "Purine metabolism", "name": "Deoxyadenosine:orthophosphate ribosyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R02557", "ec-code": "2.4.2.1", "sbo": "SBO:0000176"}, "metabolites": {"2dr1p_c": 1.0, "dad-2_c": -1.0, "ade_c": 1.0, "pi_c": -1.0}, "id": "RC02557", "gene_reaction_rule": "WBGene00019298"}, {"subsystem": "Fructose and mannose metabolism", "name": "GDP-mannose 4,6-hydro-lyase (GDP-4-dehydro-6-deoxy-D-mannose-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00888", "ec-code": "4.2.1.47", "sbo": "SBO:0000176"}, "metabolites": {"gdpmann_c": -1.0, "gdpddman_c": 1.0, "h2o_c": 1.0}, "id": "RC00888", "gene_reaction_rule": "WBGene00000266 or WBGene00010166"}, {"subsystem": "Alanine, aspartate and glutamate metabolism", "name": "4-aminobutanoate:2-oxoglutarate aminotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01648", "ec-code": "2.6.1.19", "sbo": "SBO:0000176"}, "metabolites": {"4abut_m": -1.0, "glu-L_m": 1.0, "akg_m": -1.0, "sucsal_m": 1.0}, "id": "RM01648", "gene_reaction_rule": "WBGene00001794"}, {"subsystem": "Glycerolipid metabolism", "name": "Acyl-CoA:2-acylglycerol O-acyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03755", "ec-code": "2.3.1.22", "sbo": "SBO:0000176"}, "metabolites": {"Rtotal5coa_c": -1.0, "coa_c": 1.0, "dag_tag_c": 1.0, "mag_c": -1.0}, "id": "RC03755", "gene_reaction_rule": "((WBGene00019464 or WBGene00021818) or WBGene00020910) or WBGene00010296"}, {"subsystem": "Transport", "name": "Selenocysteine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"selcys_c": -1.0, "selcys_e": 1.0}, "id": "TCE5069", "gene_reaction_rule": ""}, {"subsystem": "Fructose and mannose metabolism", "name": "GTP:alpha-D-mannose-1-phosphate guanylyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00885", "ec-code": "2.7.7.13", "sbo": "SBO:0000176"}, "metabolites": {"man1p_c": -1.0, "ppi_c": 1.0, "gtp_c": -1.0, "h_c": -1.0, "gdpmann_c": 1.0}, "id": "RC00885", "gene_reaction_rule": "WBGene00016583 or WBGene00021628"}, {"subsystem": "Primary bile acid biosynthesis", "name": "Cholesterol 25-hydroxylase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R07218", "ec-code": "1.14.99.38", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "h2o_c": 1.0, "nadp_c": 1.0, "nadph_c": -1.0, "xol25oh_c": 1.0, "h_c": -1.0, "chsterol_c": -1.0}, "id": "RC07218", "gene_reaction_rule": "WBGene00018036"}, {"subsystem": "Transport", "name": "selenite transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"selnt_c": -1.0, "selnt_e": 1.0}, "id": "TCE5066", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Dodecanoate (n-C12:0) exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"ddca_e": -1.0}, "id": "EX02679", "gene_reaction_rule": ""}, {"subsystem": "Phenylalanine metabolism", "name": "L-Phenylalanine,tetrahydrobiopterin:oxygen oxidoreductase (4-hydroxylating) (First step)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R07211", "ec-code": "1.14.16.1", "sbo": "SBO:0000176"}, "metabolites": {"tyr-L_c": 1.0, "o2_c": -1.0, "thbpt_c": -1.0, "thbpt4acam_c": 1.0, "phe-L_c": -1.0}, "id": "RC07211", "gene_reaction_rule": "WBGene00000240"}, {"subsystem": "Isoquinoline alkaloid biosynthesis", "name": "L-Tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating) (4a-Hydroxytetrahydrobiopterin forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R07212", "ec-code": "1.14.16.2", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "thbpt_c": -1.0, "34dhphe_c": 1.0, "thbpt4acam_c": 1.0, "tyr-L_c": -1.0}, "id": "RC07212", "gene_reaction_rule": "WBGene00000296"}, {"subsystem": "Tryptophan metabolism", "name": "L-Tryptophan,tetrahydrobiopterin:oxygen oxidoreductase (5-hydroxylating) (4a-Hydroxytetrahydrobiopterin forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R07213", "ec-code": "1.14.16.4", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "trp-L_c": -1.0, "thbpt4acam_c": 1.0, "5htrp_c": 1.0, "thbpt_c": -1.0}, "id": "RC07213", "gene_reaction_rule": "WBGene00006600"}, {"subsystem": "Transport", "name": "Hypoxanthine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"hxan_e": -1.0, "hxan_c": 1.0}, "id": "TCE0544", "gene_reaction_rule": ""}, {"subsystem": "Aminoacyl-tRNA biosynthesis", "name": "L-Aspartate:tRNA(Asp) ligase (AMP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R05577", "ec-code": "6.1.1.12", "sbo": "SBO:0000176"}, "metabolites": {"asptrna_c": 1.0, "atp_c": -1.0, "ppi_c": 1.0, "amp_c": 1.0, "trnaasp_c": -1.0, "asp-L_c": -1.0}, "id": "RC05577", "gene_reaction_rule": "WBGene00001094"}, {"subsystem": "Starch and sucrose metabolism", "name": "glycogenin; glycogen synthase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R03681", "R00292"], "ec-code": ["2.4.1.186", "2.4.1.11"], "sbo": "SBO:0000176"}, "metabolites": {"nbglycogen_c": 1.0, "udp_c": 1.0, "udpg_c": -1.0, "h_c": 1.0}, "id": "RC03681", "gene_reaction_rule": "(WBGene00006863 or WBGene00012020) and WBGene00001793"}, {"subsystem": "Glycolysis / Gluconeogenesis", "name": "alpha-D-Glucose 1-phosphate 1,6-phosphomutase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00959", "ec-code": "5.4.2.2", "sbo": "SBO:0000176"}, "metabolites": {"g6p-A_c": 1.0, "g1p_c": -1.0}, "id": "RC00959", "gene_reaction_rule": "WBGene00019890 or WBGene00012803"}, {"subsystem": "Transport", "name": "L-Serine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"ser-L_c": 1.0, "ser-L_e": -1.0}, "id": "TCE1137", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "w-hydroxyl leukotriene B4 exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"leuktrB4woh_e": -1.0}, "id": "EX04853", "gene_reaction_rule": ""}, {"subsystem": "Ether lipid metabolism", "name": "Plasmanylcholine 2-acylhydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R07387", "ec-code": "3.1.1.4", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "akac2gchol_c": -1.0, "ak2lgchol_c": 1.0, "Rtotal6_c": 1.0, "h_c": 1.0}, "id": "RC07387", "gene_reaction_rule": "WBGene00019747 or WBGene00009801 or WBGene00012319 or WBGene00017026 or WBGene00019229 or WBGene00022233 or WBGene00011423 or WBGene00007419 or WBGene00044468"}, {"subsystem": "Collagen biosynthesis", "name": "Protein lysine,2-oxoglutarate:oxygen oxidoreductase (5-hydroxylating)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R03376", "ec-code": "1.14.11.4", "sbo": "SBO:0000176"}, "metabolites": {"akg_c": -1.0, "o2_c": -1.0, "pcollg5hlys_c": 1.0, "succ_c": 1.0, "pcollglys_c": -1.0, "co2_c": 1.0}, "id": "RC03376", "gene_reaction_rule": "WBGene00002497"}, {"subsystem": "Transport", "name": "Hexadecanoate (n-C16:0) transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"hdca_e": -1.0, "hdca_c": 1.0}, "id": "TCE0329", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Maltose exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"malt_e": -1.0}, "id": "EX00208", "gene_reaction_rule": ""}, {"subsystem": "Primary bile acid biosynthesis", "name": "3beta-hydroxy-Delta5-C27-steroid oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R04263", "ec-code": "1.1.1.181", "sbo": "SBO:0000176"}, "metabolites": {"nadh_c": 1.0, "xol7a_c": -1.0, "h_c": 1.0, "nad_c": -1.0, "xol7aone_c": 1.0}, "id": "RC04262", "gene_reaction_rule": "WBGene00012394 or WBGene00022498 or WBGene00022616"}, {"subsystem": "Purine metabolism", "name": "ADP-ribose ribophosphohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01054", "ec-code": "3.6.1.13", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "r5p_c": 1.0, "amp_c": 1.0, "adprib_c": -1.0, "h_c": 2.0}, "id": "RC01054", "gene_reaction_rule": "WBGene00003579 or WBGene00003583"}, {"subsystem": "Exchange with the environment", "name": "\"3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoate\" exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"thcholstoic_e": -1.0}, "id": "EX04722", "gene_reaction_rule": ""}, {"subsystem": "Miscellaneous", "name": "NADPH:ferricytochrome-b5 oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R08539", "ec-code": "1.6.2.4", "sbo": "SBO:0000176"}, "metabolites": {"focytb_c": 2.0, "nadp_c": 1.0, "nadph_c": -1.0, "h_c": -1.0, "ficytb_c": -2.0}, "id": "RC08539", "gene_reaction_rule": "WBGene00001262"}, {"subsystem": "Ether lipid metabolism", "name": "CDP-choline:1-alkyl-2-acetylglycerol cholinephosphotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R04321", "ec-code": "2.7.8.2", "sbo": "SBO:0000176"}, "metabolites": {"acakg_c": -1.0, "cdpchol_c": -1.0, "h_c": 1.0, "paf_c": 1.0, "cmp_c": 1.0}, "id": "RC04321", "gene_reaction_rule": "WBGene00013024"}, {"subsystem": "Tryptophan metabolism", "name": "2-Amino-3-carboxymuconate semialdehyde carboxy-lyase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R04323", "ec-code": "4.1.1.45", "sbo": "SBO:0000176"}, "metabolites": {"cmusa_c": -1.0, "co2_c": 1.0, "h_c": -1.0, "am6sa_c": 1.0}, "id": "RC04323", "gene_reaction_rule": "WBGene00022104"}, {"subsystem": "Purine metabolism", "name": "10-Formyltetrahydrofolate:5-phosphoribosylglycinamide formyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R04325", "ec-code": "2.1.2.2", "sbo": "SBO:0000176"}, "metabolites": {"gar_c": -1.0, "fgam_c": 1.0, "thf_c": 1.0, "10fthf_c": -1.0, "h_c": 1.0}, "id": "RC04325", "gene_reaction_rule": "WBGene00018174"}, {"subsystem": "One carbon pool by folate", "name": "5'-Phosphoribosyl-N-formylglycinamide formation by 5,10-Methenyltetrahydrofolate", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R04326", "ec-code": "2.1.2.2", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "methf_c": -1.0, "fgam_c": 1.0, "h_c": 2.0, "gar_c": -1.0, "thf_c": 1.0}, "id": "RC04326", "gene_reaction_rule": "WBGene00018174"}, {"subsystem": "Alanine, aspartate and glutamate metabolism", "name": "L-glutamate 1-carboxy-lyase (4-aminobutanoate-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00261", "ec-code": "4.1.1.15", "sbo": "SBO:0000176"}, "metabolites": {"4abut_m": 1.0, "h_m": -1.0, "co2_m": 1.0, "glu-L_m": -1.0}, "id": "RM00261", "gene_reaction_rule": "WBGene00006762"}, {"subsystem": "Pentose phosphate pathway", "name": "ATP:D-ribose 5-phosphotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01051", "ec-code": "2.7.1.15", "sbo": "SBO:0000176"}, "metabolites": {"h_c": 1.0, "r5p_c": 1.0, "rib-D_c": -1.0, "atp_c": -1.0, "adp_c": 1.0}, "id": "RC01051", "gene_reaction_rule": "WBGene00008548"}, {"subsystem": "Exchange with the environment", "name": "7alpha-Hydroxycholest-4-en-3-one exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"xol7aone_e": -1.0}, "id": "EX05455", "gene_reaction_rule": ""}, {"subsystem": "Purine metabolism", "name": "IMP:diphosphate phospho-D-ribosyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01132", "ec-code": "2.4.2.8", "sbo": "SBO:0000176"}, "metabolites": {"ppi_c": 1.0, "hxan_c": -1.0, "prpp_c": -1.0, "imp_c": 1.0}, "id": "RC01132", "gene_reaction_rule": "WBGene00013690"}, {"subsystem": "Purine metabolism", "name": "IMP:NAD+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01130", "ec-code": "1.1.1.205", "sbo": "SBO:0000176"}, "metabolites": {"xmp_c": 1.0, "h2o_c": -1.0, "h_c": 1.0, "nad_c": -1.0, "nadh_c": 1.0, "imp_c": -1.0}, "id": "RC01130", "gene_reaction_rule": "WBGene00020682"}, {"subsystem": "Purine metabolism", "name": "ATP:dADP phosphotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01137", "ec-code": "2.7.4.6", "sbo": "SBO:0000176"}, "metabolites": {"dadp_c": -1.0, "adp_c": 1.0, "atp_c": -1.0, "datp_c": 1.0}, "id": "RC01137", "gene_reaction_rule": "WBGene00019899 or WBGene00021692 or WBGene00009119"}, {"subsystem": "Exchange with the environment", "name": "Thymine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"thym_e": -1.0}, "id": "EX00178", "gene_reaction_rule": ""}, {"subsystem": "Purine metabolism", "name": "IMP:L-aspartate ligase (GDP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01135", "ec-code": "6.3.4.4", "sbo": "SBO:0000176"}, "metabolites": {"gdp_c": 1.0, "dcamp_c": 1.0, "gtp_c": -1.0, "h_c": 2.0, "pi_c": 1.0, "imp_c": -1.0, "asp-L_c": -1.0}, "id": "RC01135", "gene_reaction_rule": "WBGene00016509"}, {"subsystem": "Purine metabolism", "name": "inosine-5-phosphate:NADP+ oxidoreductase (aminating)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01134", "ec-code": "1.7.1.7", "sbo": "SBO:0000176"}, "metabolites": {"nadp_c": 1.0, "nadph_c": -1.0, "imp_c": 1.0, "gmp_c": -1.0, "h_c": -2.0, "nh4_c": 1.0}, "id": "RC01134", "gene_reaction_rule": "WBGene00017984"}, {"subsystem": "Purine metabolism", "name": "dATP:pyruvate 2-O-phosphotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01138", "ec-code": "2.7.1.40", "sbo": "SBO:0000176"}, "metabolites": {"pep_c": -1.0, "dadp_c": -1.0, "pyr_c": 1.0, "h_c": -1.0, "datp_c": 1.0}, "id": "RC01138", "gene_reaction_rule": "WBGene00009126 or WBGene00014001"}, {"subsystem": "Peroxisomal fatty acid beta oxidation", "name": "Decanoyl-CoA:acetyl-CoA C-acyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R04742", "ec-code": "2.3.1.16", "sbo": "SBO:0000176"}, "metabolites": {"3oddcoa_c": -1.0, "coa_c": -1.0, "dcacoa_c": 1.0, "accoa_c": 1.0}, "id": "RC04742", "gene_reaction_rule": "WBGene00013284"}, {"subsystem": "Fructose and mannose metabolism", "name": "GDP-L-fucose:NADP+ 4-oxidoreductase (3,5-epimerizing)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R05692", "ec-code": "1.1.1.271", "sbo": "SBO:0000176"}, "metabolites": {"gdpfuc_c": 1.0, "nadp_c": 1.0, "nadph_c": -1.0, "gdpddman_c": -1.0, "h_c": -1.0}, "id": "RC05692", "gene_reaction_rule": "WBGene00019813"}, {"subsystem": "Aminoacyl-tRNA biosynthesis", "name": "L-Arginine:tRNA(Arg) ligase (AMP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03646", "ec-code": "6.1.1.19", "sbo": "SBO:0000176"}, "metabolites": {"argtrna_m": 1.0, "ppi_m": 1.0, "atp_m": -1.0, "arg-L_m": -1.0, "trnaarg_m": -1.0, "amp_m": 1.0}, "id": "RM03646", "gene_reaction_rule": "WBGene00004680"}, {"subsystem": "Peroxisomal fatty acid beta oxidation", "name": "myristoyl-CoA:acetylCoA C-myristoyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03991", "ec-code": "2.3.1.16", "sbo": "SBO:0000176"}, "metabolites": {"tdcoa_c": 1.0, "coa_c": -1.0, "accoa_c": 1.0, "3ohdcoa_c": -1.0}, "id": "RC03991", "gene_reaction_rule": "WBGene00013284"}, {"subsystem": "Aminoacyl-tRNA biosynthesis", "name": "L-Asparagine:tRNA(Asn) ligase (AMP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03648", "ec-code": "6.1.1.22", "sbo": "SBO:0000176"}, "metabolites": {"ppi_m": 1.0, "asn-L_m": -1.0, "atp_m": -1.0, "trnaasn_m": -1.0, "asntrna_m": 1.0, "amp_m": 1.0}, "id": "RM03648", "gene_reaction_rule": "WBGene00013447"}, {"subsystem": "Protein modification by hydroxylation", "name": "3-hydroxy-L-aspartate demand", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"h2o_c": -1.0, "pepasp3oh_c": -1.0, "pepX_c": 1.0, "asp-L_c": 1.0}, "id": "DMN0020", "gene_reaction_rule": ""}, {"subsystem": "Metal detoxification", "name": "phytochelatin demand", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"pchltn_c": -1.0}, "id": "DMN0021", "gene_reaction_rule": ""}, {"subsystem": "Riboflavin metabolism", "name": "Flavin adenine dinucleotide demand (cytosol)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"fad_c": -1.0}, "id": "DMN0022", "gene_reaction_rule": ""}, {"subsystem": "Riboflavin metabolism", "name": "Flavin adenine dinucleotide demand (mitochondrial)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"fad_m": -1.0}, "id": "DMN0023", "gene_reaction_rule": ""}, {"subsystem": "Molybdenum cofactor biosynthesis", "name": "molybdonum cofactor demand", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"moco_c": -1.0}, "id": "DMN0024", "gene_reaction_rule": ""}, {"subsystem": "Selenocompound metabolism", "name": "methylselenol demand", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"metsel_c": -1.0}, "id": "DMN0025", "gene_reaction_rule": ""}, {"subsystem": "Retinol metabolism", "name": "all trans retinal demand ", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"retinal_c": -1.0}, "id": "DMN0026", "gene_reaction_rule": ""}, {"subsystem": "Retinol metabolism", "name": "cis-retinal demand", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"retinal-cis-9_c": -1.0}, "id": "DMN0027", "gene_reaction_rule": ""}, {"subsystem": "Purine metabolism", "name": "ATP diphosphate-lyase (cyclizing, 3',5'-cyclic-AMP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00089", "ec-code": "4.6.1.1", "sbo": "SBO:0000176"}, "metabolites": {"ppi_c": 1.0, "camp_c": 1.0, "atp_c": -1.0}, "id": "RC00089", "gene_reaction_rule": "(WBGene00000068 or WBGene00000071) or WBGene00000069"}, {"subsystem": "Mitochondrial fatty acid beta oxidation", "name": "Beta oxidation of stcoa (mitochondrial)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R00392", "R02685", "R01778", "R00391"], "ec-code": ["1.3.8.7", "4.2.1.17", "1.1.1.211", "1.1.1.35", "2.3.1.16"], "sbo": "SBO:0000176"}, "metabolites": {"h2o_m": -1.0, "fad_m": -1.0, "accoa_m": 1.0, "nadh_m": 1.0, "nad_m": -1.0, "coa_m": -1.0, "h_m": 1.0, "fadh2_m": 1.0, "pmtcoa_m": 1.0, "stcoa_m": -1.0}, "id": "RMC0126", "gene_reaction_rule": "(WBGene00020812 or WBGene00019406 or WBGene00020366 or WBGene00017125) and ((WBGene00001155 or WBGene00001156) or (WBGene00020347 or WBGene00001150) or WBGene00001152) and ((WBGene00020347 or WBGene00001150) or (WBGene00007129 or WBGene00010035 or WBGene00001157 or WBGene00001158 or WBGene00019978)) and (WBGene00015125 or WBGene00009952)"}, {"subsystem": "Purine metabolism", "name": "inosine:phosphate alpha-D-ribosyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01863", "ec-code": "2.4.2.1", "sbo": "SBO:0000176"}, "metabolites": {"pi_c": -1.0, "hxan_c": 1.0, "r1p_c": 1.0, "ins_c": -1.0}, "id": "RC01863", "gene_reaction_rule": "WBGene00019298"}, {"subsystem": "Glycolysis / Gluconeogenesis", "name": "ADP:alpha-D-glucose 6-phosphotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R09085", "ec-code": "2.7.1.147", "sbo": "SBO:0000176"}, "metabolites": {"h_c": 1.0, "glc-D-A_c": -1.0, "g6p-A_c": 1.0, "adp_c": -1.0, "amp_c": 1.0}, "id": "RC09085", "gene_reaction_rule": "WBGene00016810"}, {"subsystem": "Taurine and hypotaurine metabolism", "name": "Hypotaurine oxidase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01681", "ec-code": "1.8.1.3", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "taur_c": 2.0, "hyptaur_c": -2.0, "h_c": -2.0}, "id": "RC01681", "gene_reaction_rule": ""}, {"subsystem": "Taurine and hypotaurine metabolism", "name": "3-Sulfo-L-alanine carboxy-lyase (taurine-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01682", "ec-code": "4.1.1.15", "sbo": "SBO:0000176"}, "metabolites": {"Lcyst_c": -1.0, "co2_c": 1.0, "taur_c": 1.0, "h_c": -1.0}, "id": "RC01682", "gene_reaction_rule": "WBGene00006762"}, {"subsystem": "Cysteine and methionine metabolism", "name": "3-sulfinopyruvate hydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "pyr_c": 1.0, "h_c": 1.0, "so3_c": 1.0, "3snpyr_c": -1.0}, "id": "RCC0009", "gene_reaction_rule": ""}, {"subsystem": "Pentose phosphate pathway", "name": "ATP:D-ribose-5-phosphate diphosphotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01049", "ec-code": "2.7.6.1", "sbo": "SBO:0000176"}, "metabolites": {"prpp_c": 1.0, "r5p_c": -1.0, "amp_c": 1.0, "atp_c": -1.0, "h_c": 1.0}, "id": "RC01049", "gene_reaction_rule": "WBGene00020107"}, {"subsystem": "Exchange with the environment", "name": "D-Glucosamine 6-phosphate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"gam6p_e": -1.0}, "id": "EX00352", "gene_reaction_rule": ""}, {"subsystem": "Citrate cycle (TCA cycle)", "name": "citrate hydro-lyase (cis-aconitate-forming)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": ["R01325", "R01900"], "ec-code": "4.2.1.3", "sbo": "SBO:0000176"}, "metabolites": {"icit_c": 1.0, "cit_c": -1.0}, "id": "RCC0001", "gene_reaction_rule": "WBGene00000040"}, {"subsystem": "Glycerolipid metabolism", "name": "Glycerol:NADP+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01041", "ec-code": "1.1.1.21", "sbo": "SBO:0000176"}, "metabolites": {"nadp_c": 1.0, "glyc_c": 1.0, "nadph_c": -1.0, "glyald_c": -1.0, "h_c": -1.0}, "id": "RC01041", "gene_reaction_rule": "WBGene00012722 or WBGene00016985"}, {"subsystem": "Exchange with the environment", "name": "\"3,4-Dihydroxy-L-phenylalanine\" exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"34dhphe_e": -1.0}, "id": "EX00355", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "L-Alanine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"ala-L_c": 1.0, "ala-L_e": -1.0}, "id": "TCE1297", "gene_reaction_rule": ""}, {"subsystem": "Pyrimidine metabolism", "name": "ATP:cytidine 5-phosphotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00513", "ec-code": "2.7.1.48", "sbo": "SBO:0000176"}, "metabolites": {"atp_m": -1.0, "adp_m": 1.0, "h_m": 1.0, "cytd_m": -1.0, "cmp_m": 1.0}, "id": "RM00513", "gene_reaction_rule": "WBGene00008948"}, {"subsystem": "Terpenoid backbone biosynthesis", "name": "S-Adenosyl-L-methionine:protein-C-terminal-S-farnesyl-L-cysteine O-methyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R04496", "ec-code": "2.1.1.100", "sbo": "SBO:0000176"}, "metabolites": {"amet_c": -1.0, "protSfarCmet_c": 1.0, "ahcys_c": 1.0, "h_c": 1.0, "protSfarC_c": -1.0}, "id": "RC04496", "gene_reaction_rule": "WBGene00017673 or WBGene00019710"}, {"subsystem": "Bacterial digestion", "name": "Bacterial fatty acid composition", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"fa19c11_c": 0.065863, "vacc_c": 0.09472, "fa16p1n7_c": 0.042082, "fa17c9_c": 0.311026, "Rtotal_BAC_c": -1.0, "hdca_c": 0.430027, "ttdca_c": 0.056282}, "id": "DGR0004", "gene_reaction_rule": ""}, {"subsystem": "Bacterial digestion", "name": "Bacterial phospholipid composition", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"ps_BAC_e": 0.020146, "pe_BAC_e": 0.750046, "pg_BAC_e": 0.179791, "clpn_BAC_e": 0.050017, "phospholipid_BAC_e": -1.0}, "id": "DGR0005", "gene_reaction_rule": ""}, {"subsystem": "Bacterial digestion", "name": "Bacterial soluble pool composition", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"mobd_e": 0.00625, "tma_e": 0.0002, "thm_e": 0.0002, "acser_e": 0.0002, "selcys_e": 0.0002, "pheme_e": 0.0002, "fol_e": 0.0002, "fe2_e": 0.000893, "adocbl_e": 0.0002, "acorn_e": 0.004018, "fmn_e": 0.001172, "pydx_e": 0.0002, "soluble_BAC_e": -1.0, "pydam_e": 0.0002, "pydxn_e": 0.0002, "ribflv_e": 0.000443, "fad_e": 0.002774, "cbl1_e": 0.0002, "q8_e": 0.0002, "thmpp_e": 0.000903, "pnto-R_e": 0.0002}, "id": "DGR0006", "gene_reaction_rule": ""}, {"subsystem": "Bacterial digestion", "name": "Bacterial degradation", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -6.0, "peptido_BAC_e": 0.027377, "lps_BAC_e": 0.008331, "atp_c": -6.0, "rna_BAC_e": 0.636031, "BAC_e": -1.0, "dna_BAC_e": 0.099745, "soluble_BAC_e": 1.0, "h_c": 6.0, "adp_c": 6.0, "protein_BAC_e": 5.037126, "pi_c": 6.0, "phospholipid_BAC_e": 0.129212, "glycogen_BAC_e": 0.135796}, "id": "DGR0007", "gene_reaction_rule": ""}, {"subsystem": "Bacterial digestion", "name": "Bacterial peptide degradation", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": ["3.4.23.-", "3.4.-.-"], "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "arg-L_c": 0.055304, "tyr-L_c": 0.025782, "lys-L_c": 0.064161, "trp-L_c": 0.010628, "cys-L_c": 0.017123, "his-L_c": 0.017713, "val-L_c": 0.079118, "leu-L_c": 0.084235, "asp-L_c": 0.04507, "met-L_c": 0.028735, "gly_c": 0.114544, "ile-L_c": 0.05432, "ser-L_c": 0.040346, "asn-L_c": 0.04507, "protein_BAC_c": -1.0, "pro-L_c": 0.04133, "phe-L_c": 0.034639, "gln-L_c": 0.049203, "glu-L_c": 0.049203, "ala-L_c": 0.096044, "thr-L_c": 0.047432}, "id": "DGR0001", "gene_reaction_rule": "WBGene00000214 or WBGene00000215 or WBGene00000216 or WBGene00000218 or WBGene00019682"}, {"subsystem": "Bacterial digestion", "name": "Bacterial RNA degradation", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"rna_BAC_c": -1.0, "h2o_c": -1.0, "gmp_c": 0.317684, "ump_c": 0.217527, "cmp_c": 0.197183, "amp_c": 0.267606, "h_c": 1.0}, "id": "DGR0002", "gene_reaction_rule": ""}, {"subsystem": "Bacterial digestion", "name": "Bacterial DNA degradation", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "dtmp_c": 0.246507, "dcmp_c": 0.253493, "dna_BAC_c": -1.0, "dgmp_c": 0.253493, "h_c": 1.0, "damp_c": 0.246507}, "id": "DGR0003", "gene_reaction_rule": ""}, {"subsystem": "Primary bile acid biosynthesis", "name": " cholestanetriol 26-monooxygenase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R08759", "ec-code": "1.14.13.15", "sbo": "SBO:0000176"}, "metabolites": {"thcholst_m": 1.0, "nadph_m": 1.0, "h_m": 1.0, "xoltetrol_m": -1.0, "nadp_m": -1.0}, "id": "RM08759", "gene_reaction_rule": "WBGene00000905"}, {"subsystem": "Bacterial digestion", "name": "Bacterial peptide uptake", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"protein_BAC_c": 1.0, "protein_BAC_e": -1.0}, "id": "DGR0008", "gene_reaction_rule": ""}, {"subsystem": "Bacterial digestion", "name": "Bacterial RNA uptake", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"rna_BAC_c": 1.0, "rna_BAC_e": -1.0}, "id": "DGR0009", "gene_reaction_rule": ""}, {"subsystem": "Nicotinate and nicotinamide metabolism", "name": "S-Adenosyl-L-methionine:nicotinamide N-methyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01269", "ec-code": "2.1.1.1", "sbo": "SBO:0000176"}, "metabolites": {"amet_c": -1.0, "ahcys_c": 1.0, "1mncam_c": 1.0, "ncam_c": -1.0}, "id": "RC01269", "gene_reaction_rule": "WBGene00015124 or WBGene00011573"}, {"subsystem": "Nicotinate and nicotinamide metabolism", "name": "nicotinamidase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01268", "ec-code": "3.5.1.19", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "nh4_c": 1.0, "nac_c": 1.0, "ncam_c": -1.0}, "id": "RC01268", "gene_reaction_rule": "WBGene00021395 or WBGene00013336"}, {"subsystem": "Glutathione metabolism", "name": "glutathione:L-amino-acid 5-glutamyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01262", "ec-code": "2.3.2.2", "sbo": "SBO:0000176"}, "metabolites": {"gluala_c": 1.0, "ala-L_c": -1.0, "gthrd_c": -1.0, "cgly_c": 1.0}, "id": "RC01262", "gene_reaction_rule": "WBGene00016906 or WBGene00019204 or WBGene00011393 or WBGene00020590 or WBGene00012416 or WBGene00022397"}, {"subsystem": "Arachidonic acid metabolism", "name": "Arachidonate:oxygen 5-oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01595", "ec-code": "1.13.11.34", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "5HPET_c": 1.0, "arachd_c": -1.0}, "id": "RC01595", "gene_reaction_rule": ""}, {"subsystem": "Protein modification by hydroxylation", "name": "beta-aspartyl-N-acetylglucosaminidase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01266", "ec-code": "3.2.2.11", "sbo": "SBO:0000176"}, "metabolites": {"acgam_c": 1.0, "asn-L_c": 1.0, "h2o_c": -1.0, "acBgamamAsn_c": -1.0}, "id": "RC01266", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Random peptide (special aminoacid carrier) exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"pepX_e": -1.0}, "id": "EXC0152", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Spermine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"sprm_e": -1.0}, "id": "EX00750", "gene_reaction_rule": ""}, {"subsystem": "Glycolysis / Gluconeogenesis", "name": "pyruvate:NAD+ 2-oxidoreductase (CoA-acetylating)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00209", "ec-code": ["1.2.4.1", "1.8.1.4", "2.3.1.12"], "sbo": "SBO:0000176"}, "metabolites": {"pyr_m": -1.0, "accoa_m": 1.0, "co2_m": 1.0, "nad_m": -1.0, "coa_m": -1.0, "nadh_m": 1.0}, "id": "RM00209", "gene_reaction_rule": "(WBGene00011510 and WBGene00015413) and (WBGene00007824 or WBGene00009082) and WBGene00010794"}, {"subsystem": "Exchange with the environment", "name": "Ascaroside 2 exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"ascr2_e": -1.0}, "id": "EXC0159", "gene_reaction_rule": ""}, {"subsystem": "Nicotinate and nicotinamide metabolism", "name": "poly(ADP-ribose) sink", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000632"}, "metabolites": {"polyadprib_c": -1.0}, "id": "SNK0016", "gene_reaction_rule": ""}, {"subsystem": "Glycerolipid metabolism", "name": "triglyceride (fat) sink", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000632"}, "metabolites": {"tag_c": -1.0}, "id": "SNK0014", "gene_reaction_rule": ""}, {"subsystem": "Starch and sucrose metabolism", "name": "glycogen sink", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000632"}, "metabolites": {"glycogen_c": -1.0}, "id": "SNK0012", "gene_reaction_rule": ""}, {"subsystem": "Starch and sucrose metabolism", "name": "trehalose sink", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000632"}, "metabolites": {"tre_c": -1.0}, "id": "SNK0013", "gene_reaction_rule": ""}, {"subsystem": "Primary bile acid biosynthesis", "name": "Cholesterol,NADPH:oxygen oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01463", "ec-code": "1.14.13.17", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "h2o_c": 1.0, "nadp_c": 1.0, "nadph_c": -1.0, "h_c": -1.0, "chsterol_c": -1.0, "xol7a_c": 1.0}, "id": "RC01463", "gene_reaction_rule": ""}, {"subsystem": "Glycerophospholipid metabolism", "name": "ATP:ethanolamine O-phosphotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01468", "ec-code": "2.7.1.82", "sbo": "SBO:0000176"}, "metabolites": {"h_c": 1.0, "ethamp_c": 1.0, "etha_c": -1.0, "atp_c": -1.0, "adp_c": 1.0}, "id": "RC01468", "gene_reaction_rule": "WBGene00000515 or (WBGene00000509 or WBGene00000510 or WBGene00000511 or WBGene00000512 or WBGene00000513)"}, {"subsystem": "Exchange with the environment", "name": "Methanol exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"meoh_e": -1.0}, "id": "EX00132", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "D-Alanine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"ala-D_e": -1.0}, "id": "EX00133", "gene_reaction_rule": ""}, {"subsystem": "Pyrimidine metabolism", "name": "ATP:dCMP phosphotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01665", "ec-code": "2.7.4.14", "sbo": "SBO:0000176"}, "metabolites": {"dcmp_c": -1.0, "adp_c": 1.0, "atp_c": -1.0, "dcdp_c": 1.0}, "id": "RC01665", "gene_reaction_rule": "WBGene00007812 or WBGene00009575"}, {"subsystem": "Pyrimidine metabolism", "name": "2-Deoxycytidine 5-monophosphate phosphohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01664", "ec-code": "3.1.3.5", "sbo": "SBO:0000176"}, "metabolites": {"dcmp_c": -1.0, "dcyt_c": 1.0, "h2o_c": -1.0, "pi_c": 1.0}, "id": "RC01664", "gene_reaction_rule": "WBGene00017775 or WBGene00012423 or WBGene00022201"}, {"subsystem": "Pyrimidine metabolism", "name": "dCMP aminohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01663", "ec-code": "3.5.4.12", "sbo": "SBO:0000176"}, "metabolites": {"dcmp_c": -1.0, "h2o_c": -1.0, "h_c": -1.0, "dump_c": 1.0, "nh4_c": 1.0}, "id": "RC01663", "gene_reaction_rule": "WBGene00014034"}, {"subsystem": "Exchange with the environment", "name": "myo-Inositol exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"inost_e": -1.0}, "id": "EX00137", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Putrescine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"ptrc_e": -1.0}, "id": "EX00134", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "L-Histidine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"his-L_e": -1.0}, "id": "EX00135", "gene_reaction_rule": ""}, {"subsystem": "Inositol phosphate metabolism", "name": "1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate 4-phosphohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R08981", "ec-code": "3.1.3.78", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "pi_c": 1.0, "pail45p_c": -1.0, "pail5p_c": 1.0}, "id": "RC08981", "gene_reaction_rule": "WBGene00022167"}, {"subsystem": "Citrate cycle (TCA cycle)", "name": "(S)-malate:NAD+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00342", "ec-code": "1.1.1.37", "sbo": "SBO:0000176"}, "metabolites": {"nad_m": -1.0, "oaa_m": 1.0, "h_m": 1.0, "nadh_m": 1.0, "mal-L_m": -1.0}, "id": "RM00342", "gene_reaction_rule": "WBGene00018491 or WBGene00003162"}, {"subsystem": "Citrate cycle (TCA cycle)", "name": "Pyruvate:carbon-dioxide ligase (ADP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00344", "ec-code": "6.4.1.1", "sbo": "SBO:0000176"}, "metabolites": {"pyr_m": -1.0, "hco3_m": -1.0, "atp_m": -1.0, "oaa_m": 1.0, "pi_m": 1.0, "adp_m": 1.0, "h_m": 1.0}, "id": "RM00344", "gene_reaction_rule": "WBGene00004258"}, {"subsystem": "Transport", "name": "Cytidine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"cytd_c": -1.0, "cytd_m": 1.0}, "id": "TCM0173", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "dTDP and dGDP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dtdp_m": -1.0, "dgdp_c": -1.0, "dtdp_c": 1.0, "dgdp_m": 1.0}, "id": "TCM0172", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "dGDP and dADP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dadp_c": -1.0, "dgdp_c": 1.0, "dgdp_m": -1.0, "dadp_m": 1.0}, "id": "TCM0171", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "4-Methyl-2-oxopentanoate transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"4mop_m": 1.0, "4mop_c": -1.0}, "id": "TCM0170", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "L-3-Amino-isobutanoate transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"3aib_c": 1.0, "3aib_m": -1.0}, "id": "TCM0177", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Protoheme transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"pheme_m": -1.0, "pheme_c": 1.0}, "id": "TCM0176", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "dUDP and dADP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dadp_c": 1.0, "dudp_m": 1.0, "dudp_c": -1.0, "dadp_m": -1.0}, "id": "TCM0175", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "heptaglutamyl folate (THF) transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"7thf_c": 1.0, "7thf_m": -1.0}, "id": "TCM0174", "gene_reaction_rule": ""}, {"subsystem": "Biomass assembly", "name": "Fatty acid conversions (Rtotal3)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"odecoa_c": -0.070249, "dlnlcgcoa_c": -0.026969, "stcoa_c": -0.041849, "tmndnccoa_c": -0.033888, "fa15p0isocoa_c": -0.077813, "eicostetcoa_c": -0.016289, "vacccoa_c": -0.170938, "pmtcoa_c": -0.051607, "fa17p0isocoa_c": -0.039136, "fa17c9coa_c": -0.354879, "lnlccoa_c": -0.035378, "fa16p1n7coa_c": -0.02991, "arachdcoa_c": -0.008687, "lgnccoa_c": -0.008964, "fa19c11coa_c": -0.000111, "Rtotal3coa_c": 1.0, "tdcoa_c": -0.033335}, "id": "BIO0005", "gene_reaction_rule": ""}, {"subsystem": "Biomass assembly", "name": "DNA synthesis", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00379", "ec-code": "2.7.7.7", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -0.368, "atp_c": -0.368, "datp_c": -0.325, "ppi_c": 1.0, "dctp_c": -0.175, "dgtp_c": -0.175, "h_c": 0.368, "adp_c": 0.368, "DNA_c": 1.0, "pi_c": 0.368, "dttp_c": -0.325}, "id": "BIO0004", "gene_reaction_rule": "WBGene00012936 and WBGene00009368 and WBGene00017237 and WBGene00008645 and WBGene00019380 and WBGene00013258 and (WBGene00020964 or WBGene00021905) and WBGene00021344 and WBGene00013150 and WBGene00018721 and WBGene00017696 and WBGene00020823 and WBGene00001002 and WBGene00008722 and (WBGene00004180 or WBGene00020761) and WBGene00004181 and WBGene00011016"}, {"subsystem": "Biomass assembly", "name": "Fatty acid conversions (Rtotal7)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"Rtotal7_c": 1.0, "ocdca_c": -1.0}, "id": "BIO0007", "gene_reaction_rule": ""}, {"subsystem": "Biomass assembly", "name": "Fatty acid conversions (Rtotal)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"Rtotalcoa_c": 1.0, "odecoa_c": -0.025021, "dlnlcgcoa_c": -0.071255, "lnlccoa_c": -0.052693, "tmndnccoa_c": -0.233615, "fa15p0isocoa_c": -0.023869, "eicostetcoa_c": -0.099154, "vacccoa_c": -0.170596, "pmtcoa_c": -0.051383, "fa17p0isocoa_c": -0.030888, "fa17c9coa_c": -0.080196, "stcoa_c": -0.105017, "fa16p1n7coa_c": -0.011369, "arachdcoa_c": -0.026371, "lgnccoa_c": -0.008707, "fa19c11coa_c": -1e-05, "tdcoa_c": -0.009855}, "id": "BIO0006", "gene_reaction_rule": ""}, {"subsystem": "Biomass assembly", "name": "Protein synthesis (mitochondrial)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"trnaglu_m": 0.067386, "trnahis_m": 0.01782, "tyrtrna_m": -0.026832, "trnagln_m": 0.037694, "trnaasp_m": 0.064946, "prot_mito_m": 1.0, "mettrna_m": -0.020458, "h2o_m": -2.324, "trnaphe_m": 0.035592, "trptrna_m": -0.008944, "phetrna_m": -0.035592, "trnaval_m": 0.075105, "h_m": 3.324, "argtrna_m": -0.048846, "atp_m": -0.324, "gdp_m": 2.0, "iletrna_m": -0.053231, "valtrna_m": -0.075105, "leutrna_m": -0.082051, "cystrna_m": -0.008665, "lystrna_m": -0.071622, "trnacys_m": 0.008665, "adp_m": 0.324, "trnaile_m": 0.053231, "trnalys_m": 0.071622, "asptrna_m": -0.064946, "histrna_m": -0.01782, "trnaala_m": 0.111867, "trnatrp_m": 0.008944, "trnaser_m": 0.045815, "trnamet_m": 0.020458, "glutrna_m": -0.067386, "alatrna_m": -0.111867, "trnaasn_m": 0.035405, "trnagly_m": 0.094618, "trnaarg_m": 0.048846, "protrna_m": -0.043238, "thrtrna_m": -0.049868, "trnapro_m": 0.043238, "glytrna_m": -0.094618, "glntrna_m": -0.037694, "trnathr_m": 0.049868, "pi_m": 2.324, "asntrna_m": -0.035405, "trnaleu_m": 0.082051, "gtp_m": -2.0, "sertrna_m": -0.045815, "trnatyr_m": 0.026832}, "id": "BIO0001", "gene_reaction_rule": ""}, {"subsystem": "Biomass assembly", "name": "RNA synthesis", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R00444", "R00435"], "ec-code": ["2.7.7.19", "2.7.7.6"], "sbo": "SBO:0000176"}, "metabolites": {"utp_c": -0.304569, "atp_c": -0.639534, "RNA_c": 1.0, "h2o_c": -0.406032, "gtp_c": -0.233503, "h_c": 0.406032, "adp_c": 0.406032, "ctp_c": -0.228426, "pi_c": 0.406032, "ppi_c": 1.0}, "id": "BIO0003", "gene_reaction_rule": "((WBGene00009658 or WBGene00011791 or WBGene00012528) and WBGene00001596 and WBGene00014115) and (WBGene00012999 and WBGene00008781 and WBGene00000123 and WBGene00016140 and WBGene00004411 and WBGene00017300 and WBGene00013680 and WBGene00007971 and WBGene00018391 and WBGene00019246 and WBGene00007355 and WBGene00021845 and WBGene00017830 and WBGene00022400 and WBGene00021347 and WBGene00012187 and WBGene00022309 and WBGene00007616 and WBGene00009078 and WBGene00010230 and WBGene00019275 and WBGene00014111 and WBGene00016750 and WBGene00021638 and WBGene00021112 and WBGene00009159 and WBGene00021061)"}, {"subsystem": "Biomass assembly", "name": "Protein synthesis (cytoplasmic)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"trnaphe_c": 0.036544, "h2o_c": -2.324, "mettrna_c": -0.012181, "trnagln_c": 0.026184, "tyrtrna_c": -0.027882, "trnahis_c": 0.017927, "histrna_c": -0.017927, "trnaglu_c": 0.085568, "trnaasp_c": 0.084822, "h_c": 3.324, "trnaval_c": 0.071091, "trnaile_c": 0.052143, "phetrna_c": -0.036544, "trptrna_c": -0.007259, "leutrna_c": -0.079867, "cystrna_c": -0.000208, "iletrna_c": -0.052143, "valtrna_c": -0.071091, "gdp_c": 2.0, "atp_c": -0.324, "argtrna_c": -0.042387, "adp_c": 0.324, "trnaarg_c": 0.042387, "trnaasn_c": 0.025739, "trnacys_c": 0.000208, "lystrna_c": -0.079083, "trnaala_c": 0.12769, "trnalys_c": 0.079083, "asptrna_c": -0.084822, "trnaser_c": 0.051284, "trnagly_c": 0.074691, "alatrna_c": -0.12769, "glutrna_c": -0.085568, "trnamet_c": 0.012181, "glntrna_c": -0.026184, "glytrna_c": -0.074691, "thrtrna_c": -0.052305, "trnapro_c": 0.045145, "prot_other_c": 1.0, "protrna_c": -0.045145, "sertrna_c": -0.051284, "trnatyr_c": 0.027882, "trnatrp_c": 0.007259, "gtp_c": -2.0, "trnaleu_c": 0.079867, "asntrna_c": -0.025739, "pi_c": 2.324, "trnathr_c": 0.052305}, "id": "BIO0002", "gene_reaction_rule": ""}, {"subsystem": "Biomass assembly", "name": "Glycan pooling", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"m4masn_c": -0.028141, "nm3masn_c": -0.013612, "fm2masn_c": -0.01648, "fn2m2masn_c": -0.01185, "asn-L_c": 0.156518, "chitin_c": -0.843482, "m2masn_c": -0.03835, "Glycans_c": 1.0, "nm2masn_c": -0.015623, "m3masn_c": -0.032462}, "id": "BIO0009", "gene_reaction_rule": ""}, {"subsystem": "Biomass assembly", "name": "Phospholipids assembly", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"akac2gpe_c": -0.108903, "pchol_c": -0.313837, "PhosphoL_c": 1.0, "ps_c": -0.005009, "pe_c": -0.359684, "lpchol_c": -0.015689, "akac2gchol_c": -0.009698, "pail_c": -0.015693, "sphmyln_ce_c": -0.079557, "clpn_c": -0.015696, "alkenac2gpe_c": -0.076233}, "id": "BIO0008", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "4-Hydroxy-2-quinolinecarboxylic acid exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"kynate_e": -1.0}, "id": "EX01717", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Trehalose exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"tre_e": -1.0}, "id": "EX01083", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Deoxyribose transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"drib_e": -1.0, "drib_c": 1.0}, "id": "TCE0745", "gene_reaction_rule": ""}, {"subsystem": "Phenylalanine metabolism (indirect)", "name": "2-oxoglutaramate drain", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"akgm_c": -1.0, "akgm_e": 1.0}, "id": "TCE5093", "gene_reaction_rule": ""}, {"subsystem": "Galactose metabolism", "name": "galactitol transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"galt_e": 1.0, "galt_c": -1.0}, "id": "TCE5092", "gene_reaction_rule": ""}, {"subsystem": "Primary bile acid biosynthesis", "name": "5beta-Cholestane-3alpha,7alpha,12alpha-triol,NADPH:oxygen oxidoreductase (26-hydroxylating)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R04807", "ec-code": "1.14.13.15", "sbo": "SBO:0000176"}, "metabolites": {"xoltetrol_m": 1.0, "nadph_m": -1.0, "h2o_m": 1.0, "nadp_m": 1.0, "o2_m": -1.0, "xoltriol_m": -1.0, "h_m": -1.0}, "id": "RM04807", "gene_reaction_rule": "WBGene00000905"}, {"subsystem": "Vitamin B12 metabolism", "name": "Secretion of Vitamin B12", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"h2o_c": -1.0, "atp_c": -1.0, "adocbl_c": -1.0, "adocbl_e": 1.0, "h_c": 1.0, "adp_c": 1.0, "pi_c": 1.0}, "id": "TCE5097", "gene_reaction_rule": "WBGene00003411"}, {"subsystem": "Ubiquinone and other terpenoid-quinone biosynthesis", "name": "4-Hydroxybenzoate secretion", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"4hbz_c": -1.0, "4hbz_e": 1.0}, "id": "TCE5096", "gene_reaction_rule": ""}, {"subsystem": "Carnitine shuttle", "name": "Acyl-CoA:L-carnitine O-acyltransferase II (cis-9,10-methylenehexadecanoyl-CoA)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "2.3.1.21", "sbo": "SBO:0000176"}, "metabolites": {"coa_m": -1.0, "fa17c9crn_m": -1.0, "crn_m": 1.0, "fa17c9coa_m": 1.0}, "id": "RMC0119", "gene_reaction_rule": "WBGene00011122"}, {"subsystem": "Carnitine shuttle", "name": "Acyl-CoA:L-carnitine O-acyltransferase II (cis-3,4-methylenedecanoyl-CoA)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "2.3.1.21", "sbo": "SBO:0000176"}, "metabolites": {"coa_m": -1.0, "fa11c3crn_m": -1.0, "crn_m": 1.0, "fa11c3coa_m": 1.0}, "id": "RMC0118", "gene_reaction_rule": "WBGene00011122"}, {"subsystem": "Carnitine shuttle", "name": "Acyl-CoA:L-carnitine O-acyltransferase II (Palmitoleyl-CoA)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "2.3.1.21", "sbo": "SBO:0000176"}, "metabolites": {"fa16p1n7crn_m": -1.0, "fa16p1n7coa_m": 1.0, "coa_m": -1.0, "crn_m": 1.0}, "id": "RMC0117", "gene_reaction_rule": "WBGene00011122"}, {"subsystem": "Carnitine shuttle", "name": "Acyl-CoA:L-carnitine O-acyltransferase II (Stearoyl-CoA )", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "2.3.1.21", "sbo": "SBO:0000176"}, "metabolites": {"coa_m": -1.0, "stcrn_m": -1.0, "crn_m": 1.0, "stcoa_m": 1.0}, "id": "RMC0116", "gene_reaction_rule": "WBGene00011122"}, {"subsystem": "Carnitine shuttle", "name": "Acyl-CoA:L-carnitine O-acyltransferase II (Tetradecanoyl-CoA )", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "2.3.1.21", "sbo": "SBO:0000176"}, "metabolites": {"tdcoa_m": 1.0, "coa_m": -1.0, "crn_m": 1.0, "ttdcrn_m": -1.0}, "id": "RMC0115", "gene_reaction_rule": "WBGene00011122"}, {"subsystem": "Carnitine shuttle", "name": "Acyl-CoA:L-carnitine O-acyltransferase II (fatty acyl [C20:4]-CoA)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "2.3.1.21", "sbo": "SBO:0000176"}, "metabolites": {"coa_m": -1.0, "arachdcrn_m": -1.0, "crn_m": 1.0, "arachdcoa_m": 1.0}, "id": "RMC0114", "gene_reaction_rule": "WBGene00011122"}, {"subsystem": "Carnitine shuttle", "name": "Acyl-CoA:L-carnitine O-acyltransferase II (eicosatetranoyl CoA)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "2.3.1.21", "sbo": "SBO:0000176"}, "metabolites": {"eicostetcrn_m": -1.0, "eicostetcoa_m": 1.0, "coa_m": -1.0, "crn_m": 1.0}, "id": "RMC0113", "gene_reaction_rule": "WBGene00011122"}, {"subsystem": "Carnitine shuttle", "name": "Acyl-CoA:L-carnitine O-acyltransferase II (timnodonyl CoA)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "2.3.1.21", "sbo": "SBO:0000176"}, "metabolites": {"coa_m": -1.0, "tmndnccoa_m": 1.0, "crn_m": 1.0, "tmndnccrn_m": -1.0}, "id": "RMC0112", "gene_reaction_rule": "WBGene00011122"}, {"subsystem": "Carnitine shuttle", "name": "Acyl-CoA:L-carnitine O-acyltransferase II (dihomo-gamma-linolenyl CoA)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "2.3.1.21", "sbo": "SBO:0000176"}, "metabolites": {"dlnlcgcoa_m": 1.0, "coa_m": -1.0, "dlnlcgcrn_m": -1.0, "crn_m": 1.0}, "id": "RMC0111", "gene_reaction_rule": "WBGene00011122"}, {"subsystem": "Carnitine shuttle", "name": "Acyl-CoA:L-carnitine O-acyltransferase II (linoleic CoA)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "2.3.1.21", "sbo": "SBO:0000176"}, "metabolites": {"lnlccoa_m": 1.0, "coa_m": -1.0, "lnlccrn_m": -1.0, "crn_m": 1.0}, "id": "RMC0110", "gene_reaction_rule": "WBGene00011122"}, {"subsystem": "Transport", "name": "5,10-Methylenetetrahydrofolate uptake", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"mlthf_e": -1.0, "mlthf_c": 1.0}, "id": "TCE5303", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "UTP transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"utp_c": -1.0, "utp_e": 1.0}, "id": "TCE5302", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "ITP transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"itp_e": 1.0, "itp_c": -1.0}, "id": "TCE5301", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "UDP-D-glucuronate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"udpglcur_e": -1.0, "udpglcur_c": 1.0}, "id": "TCE5300", "gene_reaction_rule": ""}, {"subsystem": "Retinol metabolism", "name": "Palmitoyl-CoA:retinol O-acyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R02367", "ec-code": "2.3.1.76", "sbo": "SBO:0000176"}, "metabolites": {"pmtcoa_c": -1.0, "retinol_c": -1.0, "coa_c": 1.0, "retpalm_c": 1.0}, "id": "RC02367", "gene_reaction_rule": "WBGene00010408"}, {"subsystem": "Transport", "name": "3,5-Diiodo-L-tyrosine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"na1_c": 1.0, "35diotyr_e": 1.0, "35diotyr_c": -1.0, "na1_e": -1.0}, "id": "TCE5306", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"thcholstoic_e": 1.0, "na1_c": -1.0, "na1_e": 1.0, "thcholstoic_c": -1.0}, "id": "TCE5305", "gene_reaction_rule": ""}, {"subsystem": "Miscellaneous", "name": "NADPH2:quinone oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02364", "ec-code": "1.6.5.5", "sbo": "SBO:0000176"}, "metabolites": {"q_c": -1.0, "nadp_c": 1.0, "nadph_c": -1.0, "h_c": -1.0, "qh2_c": 1.0}, "id": "RC02364", "gene_reaction_rule": "WBGene00009554"}, {"subsystem": "Transport", "name": "25-Hydroxycholesterol transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"xol25oh_e": 1.0, "xol25oh_c": -1.0}, "id": "TCE5309", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "27-Hydroxycholesterol transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"xol27oh_e": 1.0, "xol27oh_c": -1.0}, "id": "TCE5308", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Aminoacetone exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"aact_e": -1.0}, "id": "EX01888", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "monoacylglycerol 2  exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"mag_e": -1.0}, "id": "EX01885", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "2-Hydroxybutyrate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"2hb_e": -1.0}, "id": "EX05984", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Prostaglandin E2 transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"prostge2_e": -1.0, "prostge2_c": 1.0}, "id": "TCE0474", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "CDP diacylglycerol  transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"cdpdag_m": 1.0, "cdpdag_c": -1.0}, "id": "TCM0195", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "CO2 transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"co2_c": 1.0, "co2_e": -1.0}, "id": "TCE1310", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Acetate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"ac_c": 1.0, "ac_e": -1.0}, "id": "TCE1311", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "H2O transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"h2o_c": 1.0, "h2o_e": -1.0}, "id": "TCE1312", "gene_reaction_rule": ""}, {"subsystem": "Valine, leucine and isoleucine degradation", "name": "(R)-Methylmalonyl-CoA CoA-carbonylmutase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00833", "ec-code": "5.4.99.2", "sbo": "SBO:0000176"}, "metabolites": {"mmcoa-R_m": -1.0, "succoa_m": 1.0}, "id": "RM00833", "gene_reaction_rule": "WBGene00014202"}, {"subsystem": "Purine metabolism", "name": "xanthine:NAD+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R02103", "ec-code": "1.17.1.4", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "xan_c": -1.0, "urate_c": 1.0, "h_c": 1.0, "nad_c": -1.0, "nadh_c": 1.0}, "id": "RC02103", "gene_reaction_rule": "WBGene00010083"}, {"subsystem": "Pyrimidine metabolism", "name": "2-Deoxyuridine 5-monophosphate phosphohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02102", "ec-code": "3.1.3.5", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "pi_c": 1.0, "duri_c": 1.0, "dump_c": -1.0}, "id": "RC02102", "gene_reaction_rule": "WBGene00017775 or WBGene00012423 or WBGene00022201"}, {"subsystem": "Pyrimidine metabolism", "name": "5,10-Methylenetetrahydrofolate:dUMP C-methyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02101", "ec-code": "2.1.1.45", "sbo": "SBO:0000176"}, "metabolites": {"dtmp_c": 1.0, "mlthf_c": -1.0, "dump_c": -1.0, "dhf_c": 1.0}, "id": "RC02101", "gene_reaction_rule": "WBGene00022455"}, {"subsystem": "Pyrimidine metabolism", "name": "dUTP nucleotidohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02100", "ec-code": ["3.6.1.19", "3.6.1.23"], "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "ppi_c": 1.0, "dutp_c": -1.0, "dump_c": 1.0, "h_c": 1.0}, "id": "RC02100", "gene_reaction_rule": "WBGene00001823 or WBGene00010609"}, {"subsystem": "Purine metabolism", "name": "Xanthine:oxygen oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02107", "ec-code": "1.17.3.2", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "h2o_c": -1.0, "urate_c": 1.0, "xan_c": -1.0, "h2o2_c": 1.0}, "id": "RC02107", "gene_reaction_rule": "WBGene00010083"}, {"subsystem": "Miscellaneous", "name": "artificial quinone conversion (q9 to q pool)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"q9_m": -1.0, "q_m": 1.0}, "id": "RMC0028", "gene_reaction_rule": ""}, {"subsystem": "Folate biosynthesis", "name": "Tetrahydrofolyl-[Glu](n):L-glutamate gamma-ligase (ADP-forming) (producing 5thf)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R04241", "R00942"], "ec-code": "6.3.2.17", "sbo": "SBO:0000176"}, "metabolites": {"h_m": 4.0, "glu-L_m": -4.0, "atp_m": -4.0, "5thf_m": 1.0, "pi_m": 4.0, "adp_m": 4.0, "thf_m": -1.0}, "id": "RMC0023", "gene_reaction_rule": "WBGene00017777"}, {"subsystem": "Miscellaneous", "name": "artificial quinone conversion (q8 to q pool)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"q_m": 1.0, "q8_m": -1.0}, "id": "RMC0027", "gene_reaction_rule": ""}, {"subsystem": "Ubiquinone and other terpenoid-quinone biosynthesis", "name": "Hydroxylation of 3-Decaprenyl-4-hydroxybenzoate (NADP)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R08770", "sbo": "SBO:0000176"}, "metabolites": {"3npdhb_m": 1.0, "nadph_m": -1.0, "h2o_m": 1.0, "nadp_m": 1.0, "o2_m": -1.0, "3nphb_m": -1.0, "h_m": -1.0}, "id": "RMC0026", "gene_reaction_rule": ""}, {"subsystem": "Folate biosynthesis", "name": "Tetrahydrofolyl-[Glu](n):L-glutamate gamma-ligase (ADP-forming) (producing 7thf)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R04241", "R00942"], "ec-code": "6.3.2.17", "sbo": "SBO:0000176"}, "metabolites": {"7thf_m": 1.0, "glu-L_m": -2.0, "atp_m": -2.0, "5thf_m": -1.0, "pi_m": 2.0, "adp_m": 2.0, "h_m": 2.0}, "id": "RMC0024", "gene_reaction_rule": "WBGene00017777"}, {"subsystem": "Arginine and proline metabolism", "name": "ATP:L-glutamate 5-phosphotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00239", "ec-code": "2.7.2.11", "sbo": "SBO:0000176"}, "metabolites": {"atp_m": -1.0, "adp_m": 1.0, "glu5p_m": 1.0, "glu-L_m": -1.0}, "id": "RM00239", "gene_reaction_rule": "WBGene00011938"}, {"subsystem": "N-Glycan biosynthesis", "name": "mannosyl-oligosaccharide glucosidase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R05979", "ec-code": "3.2.1.106", "sbo": "SBO:0000176"}, "metabolites": {"g3m8masn_c": -1.0, "g2m8masn_c": 1.0, "h2o_c": -1.0, "glc-D_c": 1.0}, "id": "RC05979", "gene_reaction_rule": "WBGene00008775"}, {"subsystem": "Transport", "name": "Nicotinate transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"nac_e": -1.0, "nac_c": 1.0}, "id": "TCE0687", "gene_reaction_rule": ""}, {"subsystem": "N-Glycan biosynthesis", "name": "GDP-mannose:glycolipid 3-alpha-D-mannosyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R05973", "ec-code": "2.4.1.132", "sbo": "SBO:0000176"}, "metabolites": {"mpdol_c": -1.0, "gdpmann_c": -1.0, "gdp_c": 1.0, "h_c": 1.0, "m1mpdol_c": 1.0}, "id": "RC05973", "gene_reaction_rule": "WBGene00017282"}, {"subsystem": "N-Glycan biosynthesis", "name": "chitobiosyldiphosphodolichol beta-mannosyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R05972", "ec-code": "2.4.1.142", "sbo": "SBO:0000176"}, "metabolites": {"mpdol_c": 1.0, "gdpmann_c": -1.0, "gdp_c": 1.0, "h_c": 1.0, "chito2pdol_c": -1.0}, "id": "RC05972", "gene_reaction_rule": "WBGene00020820"}, {"subsystem": "Transport", "name": "1-Methylnicotinamide import", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"1mncam_e": -1.0, "1mncam_c": 1.0}, "id": "TCE5415", "gene_reaction_rule": ""}, {"subsystem": "N-Glycan biosynthesis", "name": "UDP-GlcNAc:dolichyl-pyrophosphoryl-GlcNAc GlcNAc transferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R05970", "ec-code": "2.4.1.141", "sbo": "SBO:0000176"}, "metabolites": {"naglc2p_c": -1.0, "uacgam_c": -1.0, "udp_c": 1.0, "h_c": 1.0, "chito2pdol_c": 1.0}, "id": "RC05970", "gene_reaction_rule": "(WBGene00019725 or WBGene00011193)"}, {"subsystem": "Arachidonic acid metabolism", "name": "Arachidonic acid:oxygen 1-oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R07041", "ec-code": "1.14.15.3", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "h2o_c": 1.0, "nadp_c": 1.0, "nadph_c": -1.0, "h_c": -1.0, "20HETE_c": 1.0, "arachd_c": -1.0}, "id": "RC07041", "gene_reaction_rule": "WBGene00008499 or WBGene00009226"}, {"subsystem": "N-Glycan biosynthesis", "name": "dolichyl-diphosphooligosaccharide-protein glycotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R05976", "ec-code": "2.4.99.18", "sbo": "SBO:0000176"}, "metabolites": {"doldp_c": 1.0, "g3m8masn_c": 1.0, "Asn-X-Ser/Thr_c": -1.0, "g3m8mpdol_c": -1.0, "h_c": 1.0}, "id": "RC05976", "gene_reaction_rule": "WBGene00020437"}, {"subsystem": "Transport", "name": "Spermine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"sprm_c": 1.0, "sprm_e": -1.0}, "id": "TCE5411", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Spermidine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"spmd_c": -1.0, "spmd_e": 1.0}, "id": "TCE5410", "gene_reaction_rule": ""}, {"subsystem": "Collagen biosynthesis", "name": "Procollagen-L-proline,2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03219", "ec-code": "1.14.11.2", "sbo": "SBO:0000176"}, "metabolites": {"akg_c": -1.0, "o2_c": -1.0, "succ_c": 1.0, "pcollgpro_c": -1.0, "pcollg4hpro_c": 1.0, "co2_c": 1.0}, "id": "RC03219", "gene_reaction_rule": "WBGene00015773 or WBGene00077688 or WBGene00001077 or WBGene00004025 or WBGene00004026 or WBGene00012815"}, {"subsystem": "Glutathione metabolism", "name": "(5-L-Glutamyl)-L-alanine 5-glutamyltransferase (cyclizing)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03749", "ec-code": "2.3.2.4", "sbo": "SBO:0000176"}, "metabolites": {"ala-L_c": 1.0, "gluala_c": -1.0, "5oxpro_c": 1.0}, "id": "RC03749", "gene_reaction_rule": "WBGene00016629"}, {"subsystem": "Exchange with the environment", "name": "Deoxyguanosine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"dgsn_e": -1.0}, "id": "EX00330", "gene_reaction_rule": ""}, {"subsystem": "One carbon pool by folate", "name": "5,10-Methenyltetrahydrofolate 5-hydrolase (decyclizing)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01655", "ec-code": "3.5.4.9", "sbo": "SBO:0000176"}, "metabolites": {"methf_m": -1.0, "h2o_m": -1.0, "h_m": 1.0, "10fthf_m": 1.0}, "id": "RM01655", "gene_reaction_rule": "WBGene00019492 or WBGene00000929"}, {"subsystem": "Cysteine and methionine metabolism", "name": "3-sulfino-L-alanine:2-oxoglutarate aminotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R02619", "ec-code": "2.6.1.1", "sbo": "SBO:0000176"}, "metabolites": {"akg_c": -1.0, "glu-L_c": 1.0, "3snpyr_c": 1.0, "h_c": -1.0, "3sala_c": -1.0}, "id": "RC02619", "gene_reaction_rule": "WBGene00020146"}, {"subsystem": "Pyrimidine metabolism (indirect)", "name": "(R)-3-Amino-2-methylpropanoate:pyruvate aminotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R02050", "ec-code": "2.6.1.40", "sbo": "SBO:0000176"}, "metabolites": {"2mop_m": 1.0, "ala-L_m": 1.0, "3aib-D_m": -1.0, "pyr_m": -1.0}, "id": "RM02050", "gene_reaction_rule": "WBGene00020382"}, {"subsystem": "Glycerophospholipid metabolism", "name": "Phsophatidyl-L-serine carboxy-lyase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02055", "ec-code": "4.1.1.65", "sbo": "SBO:0000176"}, "metabolites": {"pe_m": 1.0, "h_m": -1.0, "ps_m": -1.0, "co2_m": 1.0}, "id": "RM02055", "gene_reaction_rule": "WBGene00015159"}, {"subsystem": "Inositol phosphate metabolism", "name": "ATP:1-Phosphatidyl-1D-myo-inositol 4-phosphotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03361", "ec-code": "2.7.1.67", "sbo": "SBO:0000176"}, "metabolites": {"h_c": 1.0, "pail4p_c": 1.0, "pail_c": -1.0, "atp_c": -1.0, "adp_c": 1.0}, "id": "RC03361", "gene_reaction_rule": "(WBGene00008346 or WBGene00022501) or (WBGene00013557 or WBGene00018076)"}, {"subsystem": "Inositol phosphate metabolism", "name": "ATP:1-phosphatidyl-1D-myo-inositol 3-phosphotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03362", "ec-code": "2.7.1.137", "sbo": "SBO:0000176"}, "metabolites": {"h_c": 1.0, "pail3p_c": 1.0, "pail_c": -1.0, "atp_c": -1.0, "adp_c": 1.0}, "id": "RC03362", "gene_reaction_rule": "WBGene00006932"}, {"subsystem": "Inositol phosphate metabolism", "name": "1-Phosphatidyl-1D-myo-inositol 3-phosphate 3-phosphohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03363", "ec-code": "3.1.3.64", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "pi_c": 1.0, "pail3p_c": -1.0, "pail_c": 1.0}, "id": "RC03363", "gene_reaction_rule": "WBGene00003476"}, {"subsystem": "Inositol phosphate metabolism", "name": "Phosphatidyl-myo-inositol-4,5-bisphosphate 4-phosphohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R04404", "ec-code": "3.1.3.36", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "pi_c": 1.0, "pail4p_c": 1.0, "pail45p_c": -1.0}, "id": "RC04404", "gene_reaction_rule": "WBGene00012016 or WBGene00007620 or WBGene00006763"}, {"subsystem": "Inositol phosphate metabolism", "name": "ATP:1-phosphatidyl-1D-myo-inositol-3-phosphate 5-phosphotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R05802", "ec-code": "2.7.1.150", "sbo": "SBO:0000176"}, "metabolites": {"h_c": 1.0, "pail35p_c": 1.0, "pail3p_c": -1.0, "atp_c": -1.0, "adp_c": 1.0}, "id": "RC05802", "gene_reaction_rule": "WBGene00004089"}, {"subsystem": "Transport", "name": "arachidonic acid transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"arachd_e": -1.0, "arachd_c": 1.0}, "id": "TCE0352", "gene_reaction_rule": ""}, {"subsystem": "Purine metabolism", "name": "GDP phosphohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00328", "ec-code": "3.6.1.6", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "gmp_c": 1.0, "gdp_c": -1.0, "h_c": 1.0, "pi_c": 1.0}, "id": "RC00328", "gene_reaction_rule": "(WBGene00044355 or WBGene00017244) or WBGene00003254 or WBGene00010697"}, {"subsystem": "Tryptophan metabolism", "name": "L-Kynurenine hydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00987", "ec-code": "3.7.1.3", "sbo": "SBO:0000176"}, "metabolites": {"h_c": 1.0, "ala-L_c": 1.0, "h2o_c": -1.0, "Lkynr_c": -1.0, "anth_c": 1.0}, "id": "RC00987", "gene_reaction_rule": "WBGene00015802"}, {"subsystem": "Tryptophan metabolism", "name": "N-Formylanthranilate amidohydrolase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00988", "ec-code": "3.5.1.9", "sbo": "SBO:0000176"}, "metabolites": {"nformanth_c": -1.0, "anth_c": 1.0, "h2o_c": -1.0, "h_c": 1.0, "for_c": 1.0}, "id": "RC00988", "gene_reaction_rule": "WBGene00017051"}, {"subsystem": "Folate biosynthesis", "name": "2-Amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl) dihydropteridine triphosphate phosphohydrolase (alkaline optimum)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R04620", "ec-code": "3.1.3.1", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -3.0, "dhnpt_c": 1.0, "h_c": 2.0, "pi_c": 3.0, "ahdt_c": -1.0}, "id": "RC04620", "gene_reaction_rule": "WBGene00013646"}, {"subsystem": "Biosynthesis of unsaturated fatty acids", "name": "Archidonyl-CoA thioesterase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R08183", "ec-code": "3.1.2.2", "sbo": "SBO:0000176"}, "metabolites": {"arachdcoa_c": -1.0, "h2o_c": -1.0, "coa_c": 1.0, "h_c": 1.0, "arachd_c": 1.0}, "id": "RC08183", "gene_reaction_rule": " WBGene00019404 or (WBGene00020989 or WBGene00020258) or WBGene00007857 or (WBGene00015887  or WBGene00015889  or WBGene00016511  or WBGene00017781) "}, {"subsystem": "Tyrosine metabolism", "name": "4-Maleylacetoacetate cis-trans-isomerase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03181", "ec-code": "5.2.1.2", "sbo": "SBO:0000176"}, "metabolites": {"4fumacac_c": 1.0, "4mlacac_c": -1.0}, "id": "RC03181", "gene_reaction_rule": "WBGene00021817 or WBGene00001790 or WBGene00001791"}, {"subsystem": "Miscellaneous", "name": "Adenosine 3,5-bisphosphate 3-phosphohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00188", "ec-code": "3.1.3.7", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "pi_c": 1.0, "pap_c": -1.0, "amp_c": 1.0}, "id": "RC00188", "gene_reaction_rule": "WBGene00044063 or WBGene00012390"}, {"subsystem": "Terpenoid backbone biosynthesis", "name": "Isopentenyl-diphosphate delta3-delta2-isomerase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01123", "ec-code": "5.3.3.2", "sbo": "SBO:0000176"}, "metabolites": {"dmpp_c": 1.0, "ipdp_c": -1.0}, "id": "RC01123", "gene_reaction_rule": "WBGene00019460"}, {"subsystem": "One carbon pool by folate", "name": "5-Formyltetrahydrofolate cyclo-ligase (ADP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02301", "ec-code": "6.3.3.2", "sbo": "SBO:0000176"}, "metabolites": {"atp_m": -1.0, "adp_m": 1.0, "methf_m": 1.0, "pi_m": 1.0, "5fthf_m": -1.0}, "id": "RM02301", "gene_reaction_rule": "WBGene00013708"}, {"subsystem": "Purine metabolism", "name": "IMP 1,2-hydrolase (decyclizing)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01127", "ec-code": ["2.1.2.3", "3.5.4.10"], "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "fprica_c": 1.0, "imp_c": -1.0}, "id": "RC01127", "gene_reaction_rule": "WBGene00016957"}, {"subsystem": "Purine metabolism", "name": "AMP aminohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00181", "ec-code": "3.5.4.6", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "nh4_c": 1.0, "amp_c": -1.0, "imp_c": 1.0, "h_c": -1.0}, "id": "RC00181", "gene_reaction_rule": "WBGene00016415"}, {"subsystem": "Purine metabolism", "name": "Adenosine 5-monophosphate phosphohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00183", "ec-code": "3.1.3.5", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "pi_c": 1.0, "adn_c": 1.0, "amp_c": -1.0}, "id": "RC00183", "gene_reaction_rule": "WBGene00017775 or WBGene00012423 or WBGene00022201"}, {"subsystem": "Purine metabolism", "name": "ATP:adenosine 5-phosphotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00185", "ec-code": "2.7.1.20", "sbo": "SBO:0000176"}, "metabolites": {"h_c": 1.0, "adn_c": -1.0, "adp_c": 1.0, "atp_c": -1.0, "amp_c": 1.0}, "id": "RC00185", "gene_reaction_rule": "WBGene00011128"}, {"subsystem": "Transport", "name": "L-2-Aminoadipate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"L2aadp_c": 1.0, "L2aadp_e": -1.0}, "id": "TCE5346", "gene_reaction_rule": ""}, {"subsystem": "Glycolysis / Gluconeogenesis", "name": "GTP:oxaloacetate carboxy-lyase (adding GTP, phosphoenolpyruvate-forming)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00431", "ec-code": "4.1.1.32", "sbo": "SBO:0000176"}, "metabolites": {"pep_c": 1.0, "gdp_c": 1.0, "co2_c": 1.0, "gtp_c": -1.0, "oaa_c": -1.0}, "id": "RC00431", "gene_reaction_rule": "WBGene00021043 or WBGene00011232 or WBGene00019151"}, {"subsystem": "Exchange with the environment", "name": "25-Hydroxycholesterol exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"xol25oh_e": -1.0}, "id": "EX15519", "gene_reaction_rule": ""}, {"subsystem": "Purine metabolism", "name": "GTP diphosphate-lyase (cyclizing, 3',5'-cyclic-GMP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00434", "ec-code": ["4.6.1.1", "4.6.1.2"], "sbo": "SBO:0000176"}, "metabolites": {"ppi_c": 1.0, "gtp_c": -1.0, "35cgmp_c": 1.0}, "id": "RC00434", "gene_reaction_rule": "((WBGene00001528 or WBGene00001538 or WBGene00001540 or WBGene00001541 or WBGene00001543 or WBGene00001529 or WBGene00001545 or WBGene00001546 or WBGene00001548 or WBGene00001530 or WBGene00001554 or WBGene00001532 or WBGene00001535) or (WBGene00001542 or WBGene00020131) or (WBGene00001551 or WBGene00001553 or WBGene00001555 or WBGene00001556 or WBGene00001557)) or (WBGene00000068 or WBGene00000071) or WBGene00000069 or (WBGene00000907 or WBGene00001544 or WBGene00001547 or WBGene00001549 or WBGene00007314 or WBGene00001552 or WBGene00001531 or WBGene00001536)"}, {"subsystem": "Aminoacyl-tRNA biosynthesis", "name": "L-Cysteine:tRNA(Cys) ligase (AMP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03650", "ec-code": "6.1.1.16", "sbo": "SBO:0000176"}, "metabolites": {"ppi_m": 1.0, "atp_m": -1.0, "cystrna_m": 1.0, "trnacys_m": -1.0, "cys-L_m": -1.0, "amp_m": 1.0}, "id": "RM03650", "gene_reaction_rule": "WBGene00000800"}, {"subsystem": "Aminoacyl-tRNA biosynthesis", "name": "L-Glutamate:tRNA(Gln) ligase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03651", "ec-code": "6.1.1.24", "sbo": "SBO:0000176"}, "metabolites": {"ppi_m": 1.0, "glu-L_m": -1.0, "trnagln_m": -1.0, "atp_m": -1.0, "glutrna_gln_m": 1.0, "amp_m": 1.0}, "id": "RM03651", "gene_reaction_rule": ""}, {"subsystem": "Aminoacyl-tRNA biosynthesis", "name": "L-Isoleucine:tRNA(Ile) ligase (AMP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03656", "ec-code": "6.1.1.5", "sbo": "SBO:0000176"}, "metabolites": {"ppi_m": 1.0, "atp_m": -1.0, "trnaile_m": -1.0, "iletrna_m": 1.0, "ile-L_m": -1.0, "amp_m": 1.0}, "id": "RM03656", "gene_reaction_rule": "WBGene00002153"}, {"subsystem": "Aminoacyl-tRNA biosynthesis", "name": "L-Leucine:tRNA(Leu) ligase (AMP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03657", "ec-code": "6.1.1.4", "sbo": "SBO:0000176"}, "metabolites": {"ppi_m": 1.0, "atp_m": -1.0, "leutrna_m": 1.0, "trnaleu_m": -1.0, "amp_m": 1.0, "leu-L_m": -1.0}, "id": "RM03657", "gene_reaction_rule": "WBGene00003074"}, {"subsystem": "Aminoacyl-tRNA biosynthesis", "name": "glycine:tRNA(Gly) ligase (AMP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03654", "ec-code": "6.1.1.14", "sbo": "SBO:0000176"}, "metabolites": {"ppi_m": 1.0, "atp_m": -1.0, "glytrna_m": 1.0, "gly_m": -1.0, "amp_m": 1.0, "trnagly_m": -1.0}, "id": "RM03654", "gene_reaction_rule": "WBGene00001744"}, {"subsystem": "Aminoacyl-tRNA biosynthesis", "name": "L-Histidine:tRNA(His) ligase (AMP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03655", "ec-code": "6.1.1.21", "sbo": "SBO:0000176"}, "metabolites": {"trnahis_m": -1.0, "ppi_m": 1.0, "atp_m": -1.0, "histrna_m": 1.0, "his-L_m": -1.0, "amp_m": 1.0}, "id": "RM03655", "gene_reaction_rule": "WBGene00002001"}, {"subsystem": "Aminoacyl-tRNA biosynthesis", "name": "L-Lysine:tRNALys ligase (AMP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03658", "ec-code": "6.1.1.6", "sbo": "SBO:0000176"}, "metabolites": {"ppi_m": 1.0, "atp_m": -1.0, "trnalys_m": -1.0, "lystrna_m": 1.0, "amp_m": 1.0, "lys-L_m": -1.0}, "id": "RM03658", "gene_reaction_rule": "WBGene00002238"}, {"subsystem": "Aminoacyl-tRNA biosynthesis", "name": "L-Methionine:tRNAMet ligase (AMP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03659", "ec-code": "6.1.1.10", "sbo": "SBO:0000176"}, "metabolites": {"ppi_m": 1.0, "atp_m": -1.0, "mettrna_m": 1.0, "met-L_m": -1.0, "trnamet_m": -1.0, "amp_m": 1.0}, "id": "RM03659", "gene_reaction_rule": "WBGene00013678"}, {"subsystem": "Protein modification", "name": "Peptide histidine sink", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000632"}, "metabolites": {"caphis_c": -1.0}, "id": "SNK1002", "gene_reaction_rule": ""}, {"subsystem": "Protein modification", "name": "Peptide diphtine sink", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000632"}, "metabolites": {"pdipht_c": -1.0}, "id": "SNK1003", "gene_reaction_rule": ""}, {"subsystem": "Thiamine metabolism", "name": "thiamine pyrophosphate demand (mitochondrial)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"thmpp_m": -1.0}, "id": "DMN0018", "gene_reaction_rule": ""}, {"subsystem": "Melanin biosynthesis", "name": "melanin demand", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"eumelanin_c": -1.0}, "id": "DMN0015", "gene_reaction_rule": ""}, {"subsystem": "Thiamine metabolism", "name": "thiamine pyrophosphate demand (cytosolic)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"thmpp_c": -1.0}, "id": "DMN0017", "gene_reaction_rule": ""}, {"subsystem": "Pyrimidine metabolism", "name": "Cytidine aminohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01878", "ec-code": "3.5.4.5", "sbo": "SBO:0000176"}, "metabolites": {"cytd_c": -1.0, "uri_c": 1.0, "h2o_c": -1.0, "h_c": -1.0, "nh4_c": 1.0}, "id": "RC01878", "gene_reaction_rule": "WBGene00000391 or WBGene00000392"}, {"subsystem": "Pyrimidine metabolism", "name": "Uridine:phosphate alpha-D-ribosyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01876", "ec-code": "2.4.2.3", "sbo": "SBO:0000176"}, "metabolites": {"uri_c": -1.0, "pi_c": -1.0, "r1p_c": 1.0, "ura_c": 1.0}, "id": "RC01876", "gene_reaction_rule": "WBGene00022817"}, {"subsystem": "Pyrimidine metabolism", "name": "Orotidine-5-phosphate:diphosphate phospho-alpha-D-ribosyl-transferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01870", "ec-code": "2.4.2.10", "sbo": "SBO:0000176"}, "metabolites": {"ppi_c": -1.0, "prpp_c": 1.0, "orot_c": 1.0, "orot5p_c": -1.0}, "id": "RC01870", "gene_reaction_rule": "WBGene00020036 or WBGene00011559"}, {"subsystem": "Tyrosine metabolism", "name": "melanine biosynthesis (merged)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R02962", "R03672", "R03674", "R04884"], "ec-code": "1.14.18.1", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -0.5, "h2o_c": 1.0, "dopaqn_c": -2.0, "ind56qn_c": 1.0, "co2_c": 1.0, "34dhphe_c": 1.0}, "id": "RCC0018", "gene_reaction_rule": "WBGene00015332 or WBGene00010661 or WBGene00009001 or WBGene00016419 or WBGene00021553 or WBGene00022231"}, {"subsystem": "Fatty acid biosynthesis", "name": "Acetyl-CoA:carbon-dioxide ligase (ADP-forming); biotin-carboxyl-carrier-protein:carbon-dioxide ligase (ADP-forming)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": ["R04386", "R04385"], "ec-code": ["6.4.1.2", "6.3.4.14"], "sbo": "SBO:0000176"}, "metabolites": {"malcoa_c": 1.0, "adp_c": 1.0, "atp_c": -1.0, "hco3_c": -1.0, "h_c": 1.0, "accoa_c": -1.0, "pi_c": 1.0}, "id": "RCC0019", "gene_reaction_rule": "WBGene00012131 or WBGene00004076"}, {"subsystem": "Purine metabolism", "name": "3'-phosphoadenylyl-sulfate sulfohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00507", "ec-code": "3.6.1.9", "sbo": "SBO:0000176"}, "metabolites": {"so4_c": 1.0, "h2o_c": -1.0, "pap_c": 1.0, "h_c": 2.0, "paps_c": -1.0}, "id": "RC00507", "gene_reaction_rule": "WBGene00007753 or WBGene00007755"}, {"subsystem": "Cysteine and methionine metabolism", "name": "5-(methylthio)-2,3-dioxopentyl-phosphate phosphohydrolase (isomerizing); 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one:oxygen oxidoreductase (formate-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R07395", "R07364"], "ec-code": ["3.1.3.77", "1.13.11.54"], "sbo": "SBO:0000176"}, "metabolites": {"dkmpp_c": -1.0, "h2o_c": -1.0, "o2_c": -1.0, "2kmb_c": 1.0, "h_c": 2.0, "for_c": 1.0, "pi_c": 1.0}, "id": "RCC0010", "gene_reaction_rule": "WBGene00010286 and (WBGene00009636 or WBGene00020149)"}, {"subsystem": "Pyrimidine metabolism", "name": "uracil hydro-lyase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01055", "ec-code": "3.2.-.-", "sbo": "SBO:0000176"}, "metabolites": {"ura_c": -1.0, "r5p_c": -1.0, "psd5p_c": 1.0, "h2o_c": 1.0}, "id": "RC01055", "gene_reaction_rule": "WBGene00020765"}, {"subsystem": "Pentose phosphate pathway", "name": "D-ribose-5-phosphate aldose-ketose-isomerase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01056", "ec-code": "5.3.1.6", "sbo": "SBO:0000176"}, "metabolites": {"r5p_c": -1.0, "ru5p-D_c": 1.0}, "id": "RC01056", "gene_reaction_rule": "WBGene00015101"}, {"subsystem": "Pentose phosphate pathway", "name": "D-Ribose 1,5-phosphomutase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01057", "ec-code": ["5.4.2.2", "5.4.2.7"], "sbo": "SBO:0000176"}, "metabolites": {"r5p_c": 1.0, "r1p_c": -1.0}, "id": "RC01057", "gene_reaction_rule": "WBGene00019890 or WBGene00012803"}, {"subsystem": "Purine metabolism", "name": "ATP:adenylylsulfate 3-phosphotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00509", "ec-code": "2.7.1.25", "sbo": "SBO:0000176"}, "metabolites": {"h_c": 1.0, "paps_c": 1.0, "aps_c": -1.0, "atp_c": -1.0, "adp_c": 1.0}, "id": "RC00509", "gene_reaction_rule": "WBGene00004091"}, {"subsystem": "Sulfur metabolism", "name": "3-Phospho-5-adenylyl sulfate 3-phosphohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00508", "ec-code": "3.1.3.7", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "pi_c": 1.0, "aps_c": 1.0, "paps_c": -1.0}, "id": "RC00508", "gene_reaction_rule": "WBGene00044063 or WBGene00012390"}, {"subsystem": "Aminoacyl-tRNA biosynthesis", "name": "L-glutamate:tRNA(Glu) ligase (AMP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R05578", "ec-code": "6.1.1.17", "sbo": "SBO:0000176"}, "metabolites": {"atp_c": -1.0, "glu-L_c": -1.0, "ppi_c": 1.0, "trnaglu_c": -1.0, "amp_c": 1.0, "glutrna_c": 1.0}, "id": "RC05578", "gene_reaction_rule": "WBGene00001337"}, {"subsystem": "Transport", "name": "L-Proline transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"pro-L_c": -1.0, "pro-L_m": 1.0}, "id": "TCM1291", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "\"5,6,7,8-Tetrahydrofolate\" transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"thf_m": 1.0, "thf_c": -1.0}, "id": "TCM1290", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Phosphate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"pi_c": -1.0, "pi_m": 1.0}, "id": "TCM1292", "gene_reaction_rule": ""}, {"subsystem": "Pentose and glucuronate interconversions", "name": "L-arabinitol 4-dehydrogenase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01903", "ec-code": "1.1.1.12", "sbo": "SBO:0000176"}, "metabolites": {"abt_c": -1.0, "xylu-L_c": 1.0, "nadh_c": 1.0, "h_c": 1.0, "nad_c": -1.0}, "id": "RC01903", "gene_reaction_rule": ""}, {"subsystem": "Pentose and glucuronate interconversions", "name": "Xylitol:NADP+ 4-oxidoreductase (L-xylulose-forming)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01904", "ec-code": "1.1.1.10", "sbo": "SBO:0000176"}, "metabolites": {"xylu-L_c": -1.0, "nadp_c": 1.0, "nadph_c": -1.0, "h_c": -1.0, "xylt_c": 1.0}, "id": "RC01904", "gene_reaction_rule": "WBGene00000984"}, {"subsystem": "Pentose and glucuronate interconversions", "name": "dehydro-L-gulonate decarboxylase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01905", "ec-code": "4.1.1.34", "sbo": "SBO:0000176"}, "metabolites": {"xylu-L_c": 1.0, "co2_c": 1.0, "h_c": -1.0, "3dhguln_c": -1.0}, "id": "RC01905", "gene_reaction_rule": ""}, {"subsystem": "Vitamin B6 metabolism", "name": "ATP:pyridoxine 5-phosphotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01909", "ec-code": "2.7.1.35", "sbo": "SBO:0000176"}, "metabolites": {"pydxn_c": -1.0, "pdx5p_c": 1.0, "adp_c": 1.0, "atp_c": -1.0, "h_c": 1.0}, "id": "RC01909", "gene_reaction_rule": "WBGene00019008"}, {"subsystem": "Exchange with the environment", "name": "Ascaroside 18 exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"ascr18_e": -1.0}, "id": "EXC0181", "gene_reaction_rule": ""}, {"subsystem": "Fatty acid elongation", "name": "Palmitoyl-CoA hydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01274", "ec-code": "3.1.2.22", "sbo": "SBO:0000176"}, "metabolites": {"pmtcoa_c": -1.0, "hdca_c": 1.0, "h2o_c": -1.0, "coa_c": 1.0, "h_c": 1.0}, "id": "RC01274", "gene_reaction_rule": "WBGene00004092"}, {"subsystem": "Exchange with the environment", "name": "3-mercaptolactate-cysteine disulfide exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"mercplaccys_e": -1.0}, "id": "EXC0141", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "phospholipid component of E. coli diet exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"phospholipid_BAC_e": -1.0}, "id": "EXC0142", "gene_reaction_rule": ""}, {"subsystem": "Thiamine metabolism", "name": "ATP:thiamine diphosphotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00619", "ec-code": "2.7.6.2", "sbo": "SBO:0000176"}, "metabolites": {"thmpp_c": 1.0, "thm_c": -1.0, "amp_c": 1.0, "atp_c": -1.0, "h_c": 1.0}, "id": "RC00619", "gene_reaction_rule": "WBGene00014027"}, {"subsystem": "Fatty acid metabolism", "name": "Acetyl-CoA:acetyl-CoA C-acetyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00238", "ec-code": "2.3.1.9", "sbo": "SBO:0000176"}, "metabolites": {"accoa_m": -2.0, "coa_m": 1.0, "aacoa_m": 1.0}, "id": "RM00238", "gene_reaction_rule": "WBGene00020166 or WBGene00002183"}, {"subsystem": "Valine, leucine and isoleucine degradation", "name": "(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA:NAD+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R04203", "ec-code": ["1.1.1.178", "1.1.1.35"], "sbo": "SBO:0000176"}, "metabolites": {"nad_m": -1.0, "h_m": 1.0, "2maacoa_m": 1.0, "3hmbcoa_m": -1.0, "nadh_m": 1.0}, "id": "RM04203", "gene_reaction_rule": "WBGene00000181 or (WBGene00007129 or WBGene00010035 or WBGene00001157 or WBGene00001158 or WBGene00019978)"}, {"subsystem": "Valine, leucine and isoleucine degradation", "name": "(2S,3S)-3-Hydroxy-2-methylbutanoyl-CoA hydro-liase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R04204", "ec-code": "4.2.1.17", "sbo": "SBO:0000176"}, "metabolites": {"h2o_m": -1.0, "3hmbcoa_m": 1.0, "2mb2coa_m": -1.0}, "id": "RM04204", "gene_reaction_rule": "(WBGene00001155 or WBGene00001156) or (WBGene00020347 or WBGene00001150) or WBGene00001152"}, {"subsystem": "Glyoxylate and dicarboxylate metabolism", "name": "Phosphoglycolic acid sink", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000632"}, "metabolites": {"2pglyc_c": -1.0}, "id": "SNK0069", "gene_reaction_rule": ""}, {"subsystem": "Carnitine shuttle", "name": "Acyl-CoA:L-carnitine O-acyltransferase I (Octadecenoyl-CoA )", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "2.3.1.21", "sbo": "SBO:0000176"}, "metabolites": {"crn_c": -1.0, "odecoa_c": -1.0, "coa_c": 1.0, "odecrn_c": 1.0}, "id": "RCC0109", "gene_reaction_rule": "WBGene00012907 or WBGene00021703 or WBGene00019644 or WBGene00008629 or WBGene00020911"}, {"subsystem": "Glycerophospholipid metabolism", "name": "sn-Glycero-3-phosphoethanolamine glycerophosphohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01470", "ec-code": "3.1.4.46", "sbo": "SBO:0000176"}, "metabolites": {"h_c": 1.0, "h2o_c": -1.0, "glyc3p_c": 1.0, "etha_c": 1.0, "g3pe_c": -1.0}, "id": "RC01470", "gene_reaction_rule": "WBGene00020446 or WBGene00011929 or WBGene00022532"}, {"subsystem": "Alanine, aspartate and glutamate metabolism", "name": "L-Aspartate:2-oxoglutarate aminotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00355", "ec-code": "2.6.1.1", "sbo": "SBO:0000176"}, "metabolites": {"asp-L_m": -1.0, "oaa_m": 1.0, "glu-L_m": 1.0, "akg_m": -1.0}, "id": "RM00355", "gene_reaction_rule": "WBGene00016652 or WBGene00015778"}, {"subsystem": "Citrate cycle (TCA cycle)", "name": "acetyl-CoA:oxaloacetate C-acetyltransferase (thioester-hydrolysing)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00351", "ec-code": "2.3.3.1", "sbo": "SBO:0000176"}, "metabolites": {"cit_m": 1.0, "h2o_m": -1.0, "oaa_m": -1.0, "accoa_m": -1.0, "coa_m": 1.0, "h_m": 1.0}, "id": "RM00351", "gene_reaction_rule": "WBGene00000833"}, {"subsystem": "Exchange with the environment", "name": "Cys-Gly exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"cgly_e": -1.0}, "id": "EX01419", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Xanthurenic acid exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"xanate_e": -1.0}, "id": "EX02470", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Phenylpyruvate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"phpyr_c": 1.0, "phpyr_e": -1.0}, "id": "TCE5343", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Deoxyguanosine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dgsn_c": -1.0, "dgsn_m": 1.0}, "id": "TCM0168", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Fe2+ transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"fe2_c": -1.0, "fe2_m": 1.0}, "id": "TCM0169", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Xanthine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"xan_e": -1.0}, "id": "EX00385", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Guanosine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"gsn_e": -1.0}, "id": "EX00387", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "N-Carbamoyl-L-aspartate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"cbasp_e": -1.0}, "id": "EX00438", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "dTDP and dTTP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dtdp_c": 1.0, "dtdp_m": -1.0, "dttp_c": -1.0, "dttp_m": 1.0}, "id": "TCM0160", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "ADP and dCDP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"adp_m": -1.0, "dcdp_m": 1.0, "adp_c": 1.0, "dcdp_c": -1.0}, "id": "TCM0161", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Thiocyanate transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"tcynt_m": -1.0, "tcynt_c": 1.0}, "id": "TCM0162", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "dTDP and dCDP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dcdp_m": -1.0, "dtdp_m": 1.0, "dtdp_c": -1.0, "dcdp_c": 1.0}, "id": "TCM0163", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "ADP and dCTP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"adp_m": -1.0, "dctp_m": 1.0, "adp_c": 1.0, "dctp_c": -1.0}, "id": "TCM0165", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "dTTP and dADP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dadp_c": 1.0, "dttp_m": 1.0, "dttp_c": -1.0, "dadp_m": -1.0}, "id": "TCM0167", "gene_reaction_rule": ""}, {"subsystem": "Biomass assembly", "name": "Fatty acid composition (TAG)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"Rtotal4coa_c": 1.0, "Rtotal3coa_c": -1.0}, "id": "BIO0012", "gene_reaction_rule": ""}, {"subsystem": "Biomass assembly", "name": "Fatty acid composition (TAG)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"Rtotal5coa_c": 1.0, "Rtotal3coa_c": -1.0}, "id": "BIO0013", "gene_reaction_rule": ""}, {"subsystem": "Biomass assembly", "name": "Drain of Biomass", "upper_bound": 1000.0, "lower_bound": -0.0, "metabolites": {"h2o_c": -16.0, "atp_c": -16.0, "Biomass_c": -1.0, "h_c": 16.0, "adp_c": 16.0, "pi_c": 16.0}, "annotation": {"sbo": "SBO:0000629"}, "objective_coefficient": 1.0, "id": "BIO0010", "gene_reaction_rule": ""}, {"subsystem": "Biomass assembly", "name": "Fatty acid composition (phospholipids)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"Rtotalcoa_c": -1.0, "Rtotal2coa_c": 1.0}, "id": "BIO0011", "gene_reaction_rule": ""}, {"subsystem": "Biomass assembly", "name": "Fatty acid composition (Ether-lipid acyl)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"Rtotalcoa_c": -1.0, "Rtotal6coa_c": 1.0}, "id": "BIO0014", "gene_reaction_rule": ""}, {"subsystem": "Biomass assembly", "name": "Assembly of minor components of biomass", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"protSfar_c": -1.0, "apoISclustprot_m": 1.0, "protSgerCmet_c": -1.0, "pepd_c": -4.0, "protSfarCmet_c": -1.0, "apocytc_m": 1.0, "ISclustprot_m": -1.0, "biomass_minor_c": 1.0, "protSger_c": -1.0, "protSfarC_c": -1.0, "focytC_m": -1.0, "protCys_c": 6.0, "apohemeprotein_c": 1.0, "protSgerC_c": -1.0, "hemeprotein_c": -1.0}, "id": "BIO0015", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "\"7alpha,12alpha-Dihydroxycholest-4-en-3-one\" exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"xoldiolone_e": -1.0}, "id": "EX17339", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "3-Hydroxypropanoate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"3hpp_e": -1.0}, "id": "EX01013", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "7alpha-Hydroxy-3-oxo-4-cholestenoate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"7a3o4chlstnt_e": -1.0}, "id": "EX17337", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "\"D-Fructose 1,6-bisphosphate\" exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"fdp_e": -1.0}, "id": "EX00354", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Xanthosine 5'-phosphate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"xmp_e": -1.0}, "id": "EX00655", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Phenylpyruvate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"phpyr_e": -1.0}, "id": "EX00166", "gene_reaction_rule": ""}, {"subsystem": "Starch and sucrose metabolism", "name": "Trehalose-6-phosphate phosphohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02778", "ec-code": "3.1.3.12", "sbo": "SBO:0000176"}, "metabolites": {"tre6p_c": -1.0, "tre_c": 1.0, "h2o_c": -1.0, "pi_c": 1.0}, "id": "RC02778", "gene_reaction_rule": "WBGene00001649"}, {"subsystem": "Exchange with the environment", "name": "N-Formimidoyl-L-glutamate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"forglu_e": -1.0}, "id": "EX00439", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "N-acetylglucosamine uptake", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"acgam_c": -1.0, "acgam_e": 1.0}, "id": "TCE5080", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "N2-Acetyl-L-ornithine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"acorn_e": -1.0}, "id": "EX00437", "gene_reaction_rule": ""}, {"subsystem": "Aminoacyl-tRNA biosynthesis", "name": "L-Tyrosine:tRNA(Tyr) ligase (AMP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02918", "ec-code": "6.1.1.1", "sbo": "SBO:0000176"}, "metabolites": {"tyr-L_m": -1.0, "ppi_m": 1.0, "tyrtrna_m": 1.0, "atp_m": -1.0, "amp_m": 1.0, "trnatyr_m": -1.0}, "id": "RM02918", "gene_reaction_rule": "WBGene00006968"}, {"subsystem": "Transport", "name": "xanthurenate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"xanate_e": 1.0, "xanate_c": -1.0}, "id": "TCE5083", "gene_reaction_rule": ""}, {"subsystem": "Carnitine shuttle", "name": "Acyl-CoA:L-carnitine O-acyltransferase II (vaccenyl CoA)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "2.3.1.21", "sbo": "SBO:0000176"}, "metabolites": {"vacccoa_m": 1.0, "coa_m": -1.0, "vacccrn_m": -1.0, "crn_m": 1.0}, "id": "RMC0108", "gene_reaction_rule": "WBGene00011122"}, {"subsystem": "Carnitine shuttle", "name": "Acyl-CoA:L-carnitine O-acyltransferase II (Octadecenoyl-CoA )", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "2.3.1.21", "sbo": "SBO:0000176"}, "metabolites": {"coa_m": -1.0, "odecrn_m": -1.0, "crn_m": 1.0, "odecoa_m": 1.0}, "id": "RMC0109", "gene_reaction_rule": "WBGene00011122"}, {"subsystem": "Transport", "name": "cholesterol uptake", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"chsterol_e": -1.0, "chsterol_c": 1.0}, "id": "TCE5086", "gene_reaction_rule": "WBGene00006477"}, {"subsystem": "Exchange with the environment", "name": "Histamine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"hista_e": -1.0}, "id": "EX00388", "gene_reaction_rule": ""}, {"subsystem": "Mitochondrial fatty acid beta oxidation", "name": "Beta oxidation of fa15p0iso (mitochondrial)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R00392", "R02685", "R01778", "R00391"], "ec-code": ["1.3.8.7", "4.2.1.17", "1.1.1.211", "1.1.1.35", "2.3.1.16"], "sbo": "SBO:0000176"}, "metabolites": {"fa15p0isocoa_m": -1.0, "h2o_m": -3.0, "fad_m": -3.0, "accoa_m": 3.0, "nadh_m": 3.0, "fa9p0isocoa_m": 1.0, "nad_m": -3.0, "coa_m": -3.0, "h_m": 3.0, "fadh2_m": 3.0}, "id": "RMC0104", "gene_reaction_rule": "(WBGene00020812 or WBGene00019406 or WBGene00020366 or WBGene00017125) and ((WBGene00001155 or WBGene00001156) or (WBGene00020347 or WBGene00001150) or WBGene00001152) and ((WBGene00020347 or WBGene00001150) or (WBGene00007129 or WBGene00010035 or WBGene00001157 or WBGene00001158 or WBGene00019978)) and (WBGene00015125 or WBGene00009952)"}, {"subsystem": "Mitochondrial fatty acid beta oxidation", "name": "Beta oxidation of fa9p0iso", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R00392", "R02685", "R01778", "R00391"], "ec-code": ["1.3.8.7", "4.2.1.17", "1.1.1.211", "1.1.1.35", "2.3.1.16"], "sbo": "SBO:0000176"}, "metabolites": {"h2o_m": -2.0, "fad_m": -2.0, "accoa_m": 2.0, "nadh_m": 2.0, "fa9p0isocoa_m": -1.0, "nad_m": -2.0, "coa_m": -2.0, "h_m": 2.0, "fadh2_m": 2.0, "ivcoa_m": 1.0}, "id": "RMC0105", "gene_reaction_rule": "(WBGene00020812 or WBGene00019406 or WBGene00020366) and ((WBGene00001155 or WBGene00001156) or (WBGene00020347 or WBGene00001150) or WBGene00001152) and ((WBGene00020347 or WBGene00001150) or (WBGene00007129 or WBGene00010035 or WBGene00001157 or WBGene00001158 or WBGene00019978)) and (WBGene00015125 or WBGene00009952)"}, {"subsystem": "Mitochondrial fatty acid beta oxidation", "name": "Beta oxidation of fa19c11 (mitochondrial)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R00392", "R02685", "R01778", "R00391"], "ec-code": ["1.3.8.7", "4.2.1.17", "1.1.1.211", "1.1.1.35", "2.3.1.16"], "sbo": "SBO:0000176"}, "metabolites": {"h2o_m": -1.0, "fa17c9coa_m": 1.0, "fad_m": -1.0, "accoa_m": 1.0, "fa19c11coa_m": -1.0, "nad_m": -1.0, "coa_m": -1.0, "h_m": 1.0, "fadh2_m": 1.0, "nadh_m": 1.0}, "id": "RMC0106", "gene_reaction_rule": "(WBGene00020812 or WBGene00019406 or WBGene00020366 or WBGene00017125) and ((WBGene00001155 or WBGene00001156) or (WBGene00020347 or WBGene00001150) or WBGene00001152) and ((WBGene00020347 or WBGene00001150) or (WBGene00007129 or WBGene00010035 or WBGene00001157 or WBGene00001158 or WBGene00019978)) and (WBGene00015125 or WBGene00009952)"}, {"subsystem": "Mitochondrial fatty acid beta oxidation", "name": "Beta oxidation of fa17c9 (mitochondrial)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R00392", "R02685", "R01778", "R00391"], "ec-code": ["1.3.8.7", "4.2.1.17", "1.1.1.211", "1.1.1.35", "2.3.1.16"], "sbo": "SBO:0000176"}, "metabolites": {"fa11c3coa_m": 1.0, "h2o_m": -3.0, "fa17c9coa_m": -1.0, "fad_m": -3.0, "accoa_m": 3.0, "nadh_m": 3.0, "nad_m": -3.0, "coa_m": -3.0, "h_m": 3.0, "fadh2_m": 3.0}, "id": "RMC0107", "gene_reaction_rule": "(WBGene00020812 or WBGene00019406 or WBGene00020366 or WBGene00017125) and ((WBGene00001155 or WBGene00001156) or (WBGene00020347 or WBGene00001150) or WBGene00001152) and ((WBGene00020347 or WBGene00001150) or (WBGene00007129 or WBGene00010035 or WBGene00001157 or WBGene00001158 or WBGene00019978)) and (WBGene00015125 or WBGene00009952)"}, {"subsystem": "Mitochondrial fatty acid beta oxidation", "name": "Beta oxidation of intermediary fatty acid fa8p1n3", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R00392", "R02685", "R01778", "R00391"], "ec-code": ["1.3.8.7", "5.3.3.8", "4.2.1.17", "1.1.1.211", "1.1.1.35", "2.3.1.16"], "sbo": "SBO:0000176"}, "metabolites": {"fa8p1n3coa_m": -1.0, "h2o_m": -2.0, "btcoa_m": 1.0, "fad_m": -1.0, "accoa_m": 2.0, "nadh_m": 2.0, "nad_m": -2.0, "coa_m": -2.0, "h_m": 2.0, "fadh2_m": 1.0}, "id": "RMC0100", "gene_reaction_rule": "(WBGene00020812 or WBGene00019406 or WBGene00020366) and (WBGene00001153 or WBGene00007130) and ((WBGene00001155 or WBGene00001156) or (WBGene00020347 or WBGene00001150) or WBGene00001152) and ((WBGene00020347 or WBGene00001150) or (WBGene00007129 or WBGene00010035 or WBGene00001157 or WBGene00001158 or WBGene00019978)) and (WBGene00015125 or WBGene00009952)"}, {"subsystem": "Mitochondrial fatty acid beta oxidation", "name": "Beta oxidation of fa17p0iso (mitochondrial)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R00392", "R02685", "R01778", "R00391"], "ec-code": ["1.3.8.7", "4.2.1.17", "1.1.1.211", "1.1.1.35", "2.3.1.16"], "sbo": "SBO:0000176"}, "metabolites": {"fa15p0isocoa_m": 1.0, "h2o_m": -1.0, "fad_m": -1.0, "accoa_m": 1.0, "nadh_m": 1.0, "nad_m": -1.0, "coa_m": -1.0, "h_m": 1.0, "fadh2_m": 1.0, "fa17p0isocoa_m": -1.0}, "id": "RMC0103", "gene_reaction_rule": "(WBGene00020812 or WBGene00019406 or WBGene00020366 or WBGene00017125) and ((WBGene00001155 or WBGene00001156) or (WBGene00020347 or WBGene00001150) or WBGene00001152) and ((WBGene00020347 or WBGene00001150) or (WBGene00007129 or WBGene00010035 or WBGene00001157 or WBGene00001158 or WBGene00019978)) and (WBGene00015125 or WBGene00009952)"}, {"subsystem": "Transport", "name": "7alpha-Hydroxycholest-4-en-3-one transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"xol7aone_e": 1.0, "na1_c": -1.0, "na1_e": 1.0, "xol7aone_c": -1.0}, "id": "TCE5310", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "S-Adenosyl-L-homocysteine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"ahcys_c": 1.0, "ahcys_e": -1.0}, "id": "TCE5311", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Orotidine 5'-phosphate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"orot5p_e": -1.0, "orot5p_c": 1.0}, "id": "TCE5312", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Xanthosine 5'-phosphate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"xmp_c": 1.0, "xmp_e": -1.0}, "id": "TCE5313", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "S-Adenosylmethioninamine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"ametam_c": -1.0, "ametam_e": 1.0}, "id": "TCE5314", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "IMP transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"imp_e": -1.0, "imp_c": 1.0}, "id": "TCE5315", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "5-Amino-1-(5-Phospho-D-ribosyl)imidazole-4-carboxamide transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"aicar_c": 1.0, "aicar_e": -1.0}, "id": "TCE5316", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "D-Fructose 1,6-bisphosphate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"fdp_e": 1.0, "fdp_c": -1.0}, "id": "TCE5317", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Nicotinate D-ribonucleotide transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"nicrnt_c": 1.0, "nicrnt_e": -1.0}, "id": "TCE5318", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "dCMP transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dcmp_c": 1.0, "dcmp_e": -1.0}, "id": "TCE5319", "gene_reaction_rule": ""}, {"subsystem": "Sphingolipid metabolism", "name": "sphinganine kinase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02976", "ec-code": "2.7.1.91", "sbo": "SBO:0000176"}, "metabolites": {"sph1p_ce_c": 1.0, "sphgn_ce_c": -1.0, "adp_c": 1.0, "atp_c": -1.0, "h_c": 1.0}, "id": "RC02976", "gene_reaction_rule": "WBGene00007918"}, {"subsystem": "Starch and sucrose metabolism", "name": "1,4-alpha-D-Glucan:1,4-alpha-D-glucan 6-alpha-D-(1,4-alpha-D-glucano)-transferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02110", "ec-code": "2.4.1.18", "sbo": "SBO:0000176"}, "metabolites": {"nbglycogen_c": -1.0, "glycogen_c": 1.0}, "id": "RC02110", "gene_reaction_rule": "WBGene00011409"}, {"subsystem": "Sphingolipid metabolism", "name": "3-dehydrosphinganine reductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02978", "ec-code": "1.1.1.102", "sbo": "SBO:0000176"}, "metabolites": {"nadph_c": -1.0, "sphgn_ce_c": 1.0, "nadp_c": 1.0, "3dsphgn_ce_c": -1.0, "h_c": -1.0}, "id": "RC02978", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "L-sulfolactate transport (cytosol to extracellular)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"sl-L_e": 1.0, "sl-L_c": -1.0}, "id": "TCE5504", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "5-Oxoproline exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"5oxpro_e": -1.0}, "id": "EX01879", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "3-Methylimidazoleacetic acid exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"3mlda_e": -1.0}, "id": "EX05828", "gene_reaction_rule": ""}, {"subsystem": "Miscellaneous", "name": "oxidation of quinone", "upper_bound": 0.0, "lower_bound": 0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"q_c": 1.0, "qh2_c": -1.0}, "id": "DMN0033", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "D-Fructose exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"fru_e": -1.0}, "id": "EX00095", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "\"5-Hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoate\" exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"5HPET_e": -1.0}, "id": "EX05356", "gene_reaction_rule": ""}, {"subsystem": "N-Glycan biosynthesis", "name": "UDP-N-acetyl-D-glucosamine:dolichyl-phosphate N-acetyl-D-glucosamine phosphotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R05969", "ec-code": "2.7.8.15", "sbo": "SBO:0000176"}, "metabolites": {"uacgam_c": -1.0, "naglc2p_c": 1.0, "dolp_c": -1.0, "ump_c": 1.0}, "id": "RC05969", "gene_reaction_rule": "WBGene00013362"}, {"subsystem": "Transport", "name": "Putrescine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"ptrc_c": 1.0, "ptrc_e": -1.0}, "id": "TCE5408", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Riboflavin active secretion", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"h2o_c": -1.0, "atp_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "ribflv_e": 1.0, "pi_c": 1.0, "ribflv_c": -1.0}, "id": "TCE5409", "gene_reaction_rule": ""}, {"subsystem": "Arginine and proline metabolism", "name": "L-Proline:NAD+ 5-oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01248", "ec-code": "1.5.1.2", "sbo": "SBO:0000176"}, "metabolites": {"nad_m": 1.0, "h_m": -2.0, "nadh_m": -1.0, "1pyr5c_m": -1.0, "pro-L_m": 1.0}, "id": "RM01248", "gene_reaction_rule": "WBGene00010924 or WBGene00018904"}, {"subsystem": "Transport", "name": "S-Adenosyl-L-methionine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"amet_c": -1.0, "amet_e": 1.0}, "id": "TCE5404", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Nicotinic acid (niacin) transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"na1_c": 1.0, "nac_e": -1.0, "na1_e": -1.0, "nac_c": 1.0}, "id": "TCE5405", "gene_reaction_rule": ""}, {"subsystem": "Arachidonic acid metabolism", "name": "aryl hydrocarbon hydroxylase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R07050", "ec-code": "1.14.14.1", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "h2o_c": 1.0, "nadp_c": 1.0, "nadph_c": -1.0, "eet_c": 1.0, "h_c": -1.0, "arachd_c": -1.0}, "id": "RC07050", "gene_reaction_rule": "WBGene00015399 or WBGene00015400 or WBGene00016786 or WBGene00019473"}, {"subsystem": "Transport", "name": "Phosphatidylserine active export", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"h2o_c": -1.0, "ps_e": 1.0, "ps_c": -1.0, "atp_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "pi_c": 1.0}, "id": "TCE5407", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Sphingomyelin secretion", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"sphmyln_ce_e": 1.0, "sphmyln_ce_c": -1.0}, "id": "TCE5400", "gene_reaction_rule": ""}, {"subsystem": "Glycerolipid metabolism", "name": "Propane-1,2-diol:NAD+ 1-oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R02577", "ec-code": "1.1.1.21", "sbo": "SBO:0000176"}, "metabolites": {"lald-D_c": 1.0, "12ppd-R_c": -1.0, "nadp_c": -1.0, "nadph_c": 1.0, "h_c": 1.0}, "id": "RC02577", "gene_reaction_rule": "WBGene00012722"}, {"subsystem": "Transport", "name": "Oxidized glutathione active transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"h2o_c": -1.0, "atp_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "gthox_e": 1.0, "pi_c": 1.0, "gthox_c": -1.0}, "id": "TCE5402", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Protoheme active transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"h2o_c": -1.0, "atp_c": -1.0, "pheme_e": 1.0, "pheme_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "pi_c": 1.0}, "id": "TCE5403", "gene_reaction_rule": ""}, {"subsystem": "Glycine, serine and threonine metabolism", "name": "L-Threonine:NAD+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01465", "ec-code": "1.1.1.103", "sbo": "SBO:0000176"}, "metabolites": {"nad_m": -1.0, "2aobut_m": 1.0, "h_m": 1.0, "nadh_m": 1.0, "thr-L_m": -1.0}, "id": "RM01465", "gene_reaction_rule": "WBGene00017262"}, {"subsystem": "Ascaroside biosynthesis", "name": "Octacosanoic acid synthesis ", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": ["2.3.1.199", "1.1.1.330", "4.2.1.134", "1.3.1.93"], "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": 2.0, "malcoa_c": -2.0, "nadph_c": -4.0, "nadp_c": 4.0, "coa_c": 2.0, "h_c": -6.0, "fa28p0coa_c": 1.0, "lgnccoa_c": -1.0, "co2_c": 2.0}, "id": "RCC0210", "gene_reaction_rule": "WBGene00001239 and WBGene00002891 and WBGene00020517 and WBGene00000198"}, {"subsystem": "Ascaroside biosynthesis", "name": "very long chain ascaroside (w-ascr-C27)  synthesis", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"akg_c": -1.0, "o2_c": -2.0, "h2o_c": -1.0, "nadh_c": 1.0, "nadph_c": -1.0, "for_c": 1.0, "atp_c": -1.0, "27ascfa27p0coa_c": 1.0, "cdp_c": 1.0, "ppi_c": 1.0, "succ_c": 1.0, "nadp_c": 1.0, "h_c": 3.0, "nad_c": -1.0, "fa28p0coa_c": -1.0, "co2_c": 1.0, "cdpascl_c": -1.0, "amp_c": 1.0}, "id": "RCC0211", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Bicarbonate and Chloride transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"cl_e": -1.0, "cl_c": 1.0, "hco3_e": 2.0, "hco3_c": -2.0}, "id": "TCE0342", "gene_reaction_rule": ""}, {"subsystem": "Protein modification by hydroxylation", "name": "N4-(beta-N-Acetyl-D-glucosaminyl)-L-asparagine amidohydrolase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R03421", "ec-code": "3.5.1.26", "sbo": "SBO:0000176"}, "metabolites": {"acBgamam_c": 1.0, "h2o_c": -1.0, "asp-L_c": 1.0, "acBgamamAsn_c": -1.0, "h_c": 1.0}, "id": "RC03421", "gene_reaction_rule": "WBGene00019867"}, {"subsystem": "Aminoacyl-tRNA biosynthesis", "name": "L-Arginine:tRNA(Arg) ligase (AMP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03646", "ec-code": "6.1.1.19", "sbo": "SBO:0000176"}, "metabolites": {"arg-L_c": -1.0, "atp_c": -1.0, "ppi_c": 1.0, "argtrna_c": 1.0, "trnaarg_c": -1.0, "amp_c": 1.0}, "id": "RC03646", "gene_reaction_rule": "WBGene00004679"}, {"subsystem": "Purine metabolism", "name": "ATP:GMP phosphotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00332", "ec-code": "2.7.4.8", "sbo": "SBO:0000176"}, "metabolites": {"gmp_c": -1.0, "gdp_c": 1.0, "adp_c": 1.0, "atp_c": -1.0}, "id": "RC00332", "gene_reaction_rule": "WBGene00020190"}, {"subsystem": "Purine metabolism", "name": "ATP:GDP phosphotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00330", "ec-code": "2.7.4.6", "sbo": "SBO:0000176"}, "metabolites": {"gtp_c": 1.0, "gdp_c": -1.0, "adp_c": 1.0, "atp_c": -1.0}, "id": "RC00330", "gene_reaction_rule": "WBGene00019899 or WBGene00021692 or WBGene00009119"}, {"subsystem": "Glycine, serine and threonine metabolism", "name": "L-threonine acetaldehyde-lyase (glycine-forming)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00751", "ec-code": "4.1.2.5", "sbo": "SBO:0000176"}, "metabolites": {"gly_m": 1.0, "acald_m": 1.0, "thr-L_m": -1.0}, "id": "RM00751", "gene_reaction_rule": "WBGene00011291"}, {"subsystem": "Purine metabolism", "name": "GTP phosphohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00335", "ec-code": "3.6.5.5", "sbo": "SBO:0000176"}, "metabolites": {"gdp_c": 1.0, "h2o_c": -1.0, "pi_c": 1.0, "gtp_c": -1.0, "h_c": 1.0}, "id": "RC00335", "gene_reaction_rule": "WBGene00001093 or WBGene00001130"}, {"subsystem": "Miscellaneous", "name": "Trihexosylceramide N-acetylhexosaminohydrolase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R04184", "ec-code": "3.2.1.52", "sbo": "SBO:0000176"}, "metabolites": {"gbside_ce_c": 1.0, "acgal_c": -1.0, "h2o_c": 1.0, "thcrm_ce_c": -1.0}, "id": "RC04184", "gene_reaction_rule": "WBGene00020509 or WBGene00015767 or WBGene00012663 or WBGene00021766 or WBGene00013497"}, {"subsystem": "Purine metabolism", "name": "ATP:dGDP phosphotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01857", "ec-code": "2.7.4.6", "sbo": "SBO:0000176"}, "metabolites": {"dgtp_c": 1.0, "dgdp_c": -1.0, "adp_c": 1.0, "atp_c": -1.0}, "id": "RC01857", "gene_reaction_rule": "WBGene00019899 or WBGene00021692 or WBGene00009119"}, {"subsystem": "Miscellaneous", "name": "alpha-N-Acetyl-D-galactosaminide N-acetylgalactosaminohydrolase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R04183", "ec-code": "3.2.1.49", "sbo": "SBO:0000176"}, "metabolites": {"gbside_ce_c": -1.0, "acgal_c": -1.0, "h2o_c": 1.0, "forssman_ce_c": 1.0}, "id": "RC04183", "gene_reaction_rule": "WBGene00011095"}, {"subsystem": "Butanoate metabolism (indirect)", "name": "alphaKG reductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R08198", "ec-code": "1.1.1.95", "sbo": "SBO:0000176"}, "metabolites": {"akg_c": 1.0, "nadh_c": 1.0, "nad_c": -1.0, "2hglut_c": -1.0, "h_c": 1.0}, "id": "RC08198", "gene_reaction_rule": "WBGene00007836"}, {"subsystem": "Amino sugar and nucleotide sugar metabolism", "name": "N-Acetyl-D-glucosamine 1-phosphate 1,6-phosphomutase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R08193", "ec-code": "5.4.2.3", "sbo": "SBO:0000176"}, "metabolites": {"acgam6p_c": -1.0, "acgam1p_c": 1.0}, "id": "RC08193", "gene_reaction_rule": "WBGene00009006"}, {"subsystem": "Purine metabolism", "name": "GTP diphosphohydrolase (diphosphate-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00426", "ec-code": "3.6.1.19", "sbo": "SBO:0000176"}, "metabolites": {"ppi_c": 1.0, "h2o_c": -1.0, "gmp_c": 1.0, "gtp_c": -1.0, "h_c": 1.0}, "id": "RC00426", "gene_reaction_rule": "WBGene00001823"}, {"subsystem": "Folate biosynthesis", "name": "GTP cyclohydrolase I", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R00428", "R04639", "R05046", "R05048"], "ec-code": "3.5.4.16", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "gtp_c": -1.0, "h_c": 1.0, "for_c": 1.0, "ahdt_c": 1.0}, "id": "RC00424", "gene_reaction_rule": "WBGene00000298"}, {"subsystem": "Lysine degradation", "name": "L-2-aminoadipate:2-oxoglutarate aminotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01939", "ec-code": "2.6.1.39", "sbo": "SBO:0000176"}, "metabolites": {"2oxoadp_m": 1.0, "L2aadp_m": -1.0, "glu-L_m": 1.0, "akg_m": -1.0}, "id": "RM01939", "gene_reaction_rule": ""}, {"subsystem": "Lysine degradation", "name": "N6-(L-1,3-Dicarboxypropyl)-L-lysine:NAD+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R02313", "ec-code": "1.5.1.9", "sbo": "SBO:0000176"}, "metabolites": {"glu-L_m": 1.0, "saccrp-L_m": -1.0, "h2o_m": -1.0, "L2aadp6sa_m": 1.0, "nadh_m": 1.0, "nad_m": -1.0, "h_m": 1.0}, "id": "RM02313", "gene_reaction_rule": "WBGene00019819"}, {"subsystem": "Miscellaneous", "name": "thiosulfate:cyanide sulfurtranserase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01931", "ec-code": "2.8.1.1", "sbo": "SBO:0000176"}, "metabolites": {"so3_m": 1.0, "tsul_m": -1.0, "cyan_m": -1.0, "h_m": 1.0, "tcynt_m": 1.0}, "id": "RM01931", "gene_reaction_rule": "WBGene00008409 or WBGene00010380 or WBGene00010383 or WBGene00017387 or WBGene00022006 or WBGene00022007 or WBGene00011307"}, {"subsystem": "Butanoate metabolism (indirect)", "name": "(S)-3-Hydroxybutanoate:2-oxoglutarate oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R03225", "ec-code": "1.1.99.24", "sbo": "SBO:0000176"}, "metabolites": {"2hglut_m": 1.0, "acac_m": 1.0, "akg_m": -1.0, "S3hb_m": -1.0}, "id": "RM03225", "gene_reaction_rule": "WBGene00012608"}, {"subsystem": "Exchange with the environment", "name": "Glycolaldehyde exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"gcald_e": -1.0}, "id": "EX00266", "gene_reaction_rule": ""}, {"subsystem": "Tryptophan metabolism", "name": "Quinolinate synthase (eukaryotic)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R04293", "sbo": "SBO:0000176"}, "metabolites": {"cmusa_c": -1.0, "h2o_c": 1.0, "quln_c": 1.0, "h_c": 1.0}, "id": "RC04293", "gene_reaction_rule": ""}, {"subsystem": "Iron metabolism", "name": "fe3 storage", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"fe3_c": -1.0}, "id": "DMN0008", "gene_reaction_rule": ""}, {"subsystem": "Collagen biosynthesis", "name": "Tropocollagen formation", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"tropcollg_rest_c": 0.99814, "pcollg_tri_c": -1.0, "tropcollgtyr_c": 0.00186}, "id": "RCC0174", "gene_reaction_rule": "WBGene00006592 and WBGene00000254"}, {"subsystem": "Vitamin B12 metabolism", "name": "vitamin B12 demand (adocbl form)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"adocbl_m": -1.0}, "id": "DMN0002", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Hypoxanthine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"hxan_e": -1.0}, "id": "EX00262", "gene_reaction_rule": ""}, {"subsystem": "Vitamin B6 metabolism", "name": "pyridoxal phosphate demand", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"pydx5p_c": -1.0}, "id": "DMN0001", "gene_reaction_rule": ""}, {"subsystem": "Iron metabolism", "name": "heme A demand", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"hemea_m": -1.0}, "id": "DMN0006", "gene_reaction_rule": ""}, {"subsystem": "Iron metabolism", "name": "fe2 demand", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"fe2_c": -1.0}, "id": "DMN0007", "gene_reaction_rule": ""}, {"subsystem": "Iron metabolism", "name": "heme O demand", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"hemeo_m": -1.0}, "id": "DMN0005", "gene_reaction_rule": ""}, {"subsystem": "Glycerophospholipid metabolism", "name": "S-Adenosyl-L-methionine:methylethanolamine-phosphate N-methyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R06868", "R06869"], "ec-code": "2.1.1.103", "sbo": "SBO:0000176"}, "metabolites": {"amet_c": -2.0, "methamp_c": -1.0, "h_c": 2.0, "ahcys_c": 2.0, "cholp_c": 1.0}, "id": "RCC0021", "gene_reaction_rule": "WBGene00018811"}, {"subsystem": "Fatty acid biosynthesis", "name": "fatty acid synthetase (palmitate, n-C16:0)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R05188", "ec-code": "2.3.1.85", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": 6.0, "malcoa_c": -7.0, "nadph_c": -14.0, "nadp_c": 14.0, "coa_c": 8.0, "h_c": -20.0, "accoa_c": -1.0, "co2_c": 7.0, "hdca_c": 1.0}, "id": "RCC0020", "gene_reaction_rule": "WBGene00009342"}, {"subsystem": "Propanoate metabolism", "name": "Propionyladenylate:CoA propionyltransferase; ATP:propanoate adenylyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R00926", "R01354"], "ec-code": "6.2.1.1", "sbo": "SBO:0000176"}, "metabolites": {"atp_c": -1.0, "ppi_c": 1.0, "ppa_c": -1.0, "coa_c": -1.0, "amp_c": 1.0, "ppcoa_c": 1.0}, "id": "RCC0022", "gene_reaction_rule": "WBGene00007969"}, {"subsystem": "Inositol phosphate metabolism", "name": "CDP-diacylglycerol:myo-inositol 3-phosphatidyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01802", "ec-code": "2.7.8.11", "sbo": "SBO:0000176"}, "metabolites": {"cmp_c": 1.0, "inost_c": -1.0, "h_c": 1.0, "pail_c": 1.0, "cdpdag_c": -1.0}, "id": "RC01802", "gene_reaction_rule": "WBGene00012897"}, {"subsystem": "Glycerophospholipid metabolism", "name": "CDP-diacylglycerol:sn-glycerol-3-phosphate 3-phosphatidyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01801", "ec-code": "2.7.8.5", "sbo": "SBO:0000176"}, "metabolites": {"glyc3p_c": -1.0, "cmp_c": 1.0, "h_c": 1.0, "pgp_c": 1.0, "cdpdag_c": -1.0}, "id": "RC01801", "gene_reaction_rule": "WBGene00021677"}, {"subsystem": "N-Glycan biosynthesis", "name": "dehydrodolichol diphosphate phosphatase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "pi_c": 1.0, "dedolp_c": 1.0, "dedoldp_c": -1.0, "h_c": 1.0}, "id": "RCC0029", "gene_reaction_rule": ""}, {"subsystem": "Pyrimidine metabolism", "name": "ATP:CMP phosphotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00512", "ec-code": "2.7.4.14", "sbo": "SBO:0000176"}, "metabolites": {"cdp_c": 1.0, "adp_c": 1.0, "atp_c": -1.0, "cmp_c": -1.0}, "id": "RC00512", "gene_reaction_rule": "WBGene00007812 or WBGene00009575"}, {"subsystem": "Pyrimidine metabolism", "name": "ATP:cytidine 5-phosphotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00513", "ec-code": "2.7.1.48", "sbo": "SBO:0000176"}, "metabolites": {"cytd_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "atp_c": -1.0, "cmp_c": 1.0}, "id": "RC00513", "gene_reaction_rule": "WBGene00007089 or WBGene00008948"}, {"subsystem": "Transport", "name": "L-Glutamate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"glu-L_c": -1.0, "glu-L_m": 1.0}, "id": "TCM1284", "gene_reaction_rule": ""}, {"subsystem": "Pyrimidine metabolism", "name": "Cytidine-5-monophosphate phosphohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00511", "ec-code": "3.1.3.5", "sbo": "SBO:0000176"}, "metabolites": {"cytd_c": 1.0, "h2o_c": -1.0, "pi_c": 1.0, "cmp_c": -1.0}, "id": "RC00511", "gene_reaction_rule": "WBGene00017775 or WBGene00012423 or WBGene00022201"}, {"subsystem": "Transport", "name": "Phosphate and L-Malate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"mal-L_c": -1.0, "pi_c": 1.0, "pi_m": -1.0, "mal-L_m": 1.0}, "id": "TCM1282", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "L-Carnitine transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"crn_c": 1.0, "crn_m": -1.0}, "id": "TCM1283", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Pyruvate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"pyr_c": -1.0, "pyr_m": 1.0}, "id": "TCM1280", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "\"7,8-Dihydrofolate\" transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dhf_m": 1.0, "dhf_c": -1.0}, "id": "TCM1281", "gene_reaction_rule": ""}, {"subsystem": "Glycolysis / Gluconeogenesis", "name": "D-glyceraldehyde-3-phosphate:NAD+ oxidoreductase (phosphorylating)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01061", "ec-code": "1.2.1.12", "sbo": "SBO:0000176"}, "metabolites": {"nadh_c": 1.0, "nad_c": -1.0, "g3p_c": -1.0, "h_c": 1.0, "13dpg_c": 1.0, "pi_c": -1.0}, "id": "RC01061", "gene_reaction_rule": "WBGene00001686 or WBGene00001685 or WBGene00001684 or WBGene00001683"}, {"subsystem": "Carnitine shuttle", "name": "Carnitine-acylcarnitine translocase (occrn)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"occrn_m": 1.0, "occrn_c": -1.0}, "id": "TCM5048", "gene_reaction_rule": "WBGene00000996 or WBGene00008320"}, {"subsystem": "Exchange with the environment", "name": "1-Acyl-sn-glycero-3-phosphoserine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"acg3ps_e": -1.0}, "id": "EX18125", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Glycerol 3-phosphate transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"glyc3p_c": -1.0, "glyc3p_m": 1.0}, "id": "TCM1288", "gene_reaction_rule": ""}, {"subsystem": "Pentose phosphate pathway", "name": "2-deoxy-D-ribose-5-phosphate acetaldehyde-lyase (D-glyceraldehyde-3-phosphate-forming)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01066", "ec-code": "4.1.2.4", "sbo": "SBO:0000176"}, "metabolites": {"acald_c": 1.0, "g3p_c": 1.0, "2dr5p_c": -1.0}, "id": "RC01066", "gene_reaction_rule": "WBGene00017283"}, {"subsystem": "Exchange with the environment", "name": "Methylglyoxal exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"mthgxl_e": -1.0}, "id": "EX00546", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "4-Hydroxybenzoate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"4hbz_e": -1.0}, "id": "EX00156", "gene_reaction_rule": ""}, {"subsystem": "Cysteine and methionine metabolism", "name": "S-Adenosyl-L-homocysteine hydrolase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00192", "ec-code": "3.3.1.1", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "ahcys_c": -1.0, "adn_c": 1.0, "hcys-L_c": 1.0}, "id": "RC00192", "gene_reaction_rule": "WBGene00019322"}, {"subsystem": "Protein modification by hydroxylation", "name": "artificial transformation of peptide to peptidyl-asparagine", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"asn-L_c": -1.0, "pepasn_c": 1.0, "h2o_c": 1.0, "pepX_c": -1.0}, "id": "RCC0179", "gene_reaction_rule": ""}, {"subsystem": "Purine metabolism", "name": "AMP:diphosphate phospho-D-ribosyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00190", "ec-code": ["2.4.2.7", "2.4.2.8"], "sbo": "SBO:0000176"}, "metabolites": {"ppi_c": 1.0, "ade_c": -1.0, "amp_c": 1.0, "prpp_c": -1.0}, "id": "RC00190", "gene_reaction_rule": "WBGene00020557 or WBGene00013690"}, {"subsystem": "Purine metabolism", "name": "adenosine 3,5-phosphate 5-nucleotidohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00191", "ec-code": "3.1.4.17", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "camp_c": -1.0, "amp_c": 1.0, "h_c": 1.0}, "id": "RC00191", "gene_reaction_rule": "WBGene00020114 or WBGene00022389"}, {"subsystem": "Pyruvate metabolism", "name": "ATP:pyruvate,water phosphotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00199", "ec-code": "2.7.9.2", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "atp_c": -1.0, "pyr_c": -1.0, "pep_c": 1.0, "amp_c": 1.0, "pi_c": 1.0, "h_c": 2.0}, "id": "RC00199", "gene_reaction_rule": "WBGene00011893"}, {"subsystem": "Transport", "name": "pentaglutamyl folate (THF) transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"5thf_m": -1.0, "5thf_c": 1.0}, "id": "TCM0084", "gene_reaction_rule": ""}, {"subsystem": "Bacterial digestion", "name": "Bacterial glycogen degradation", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01821", "ec-code": "2.4.1.1", "sbo": "SBO:0000176"}, "metabolites": {"glycogen_BAC_c": -1.0, "dxtrn1_c": 0.5, "pi_c": -0.5, "g1p_c": 0.5}, "id": "DGR0028", "gene_reaction_rule": "WBGene00020696"}, {"subsystem": "Bacterial digestion", "name": "Dephosphorylation of thiamine pyrophosphate", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"thm_e": 1.0, "h_e": 1.0, "h2o_e": -2.0, "pi_e": 2.0, "thmpp_e": -1.0}, "id": "DGR0029", "gene_reaction_rule": ""}, {"subsystem": "N-Glycan biosynthesis", "name": "dolichyl-P-Glc:Man9GlcNAc2-PP-dolichol alpha-1,3-glucosyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R06262", "ec-code": "2.4.1.267", "sbo": "SBO:0000176"}, "metabolites": {"dolglcp_c": -1.0, "dolp_c": 1.0, "g1m8mpdol_c": 1.0, "m8mpdol_c": -1.0, "h_c": 1.0}, "id": "RC06262", "gene_reaction_rule": "WBGene00007435"}, {"subsystem": "N-Glycan biosynthesis", "name": "dolichyl-P-Glc:Glc1Man9GlcNAc2-PP-dolichol alpha-1,3-glucosyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R06263", "ec-code": "2.4.1.265", "sbo": "SBO:0000176"}, "metabolites": {"dolglcp_c": -1.0, "dolp_c": 1.0, "g1m8mpdol_c": -1.0, "g2m8mpdol_c": 1.0, "h_c": 1.0}, "id": "RC06263", "gene_reaction_rule": "WBGene00007464"}, {"subsystem": "N-Glycan biosynthesis", "name": "dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase (7man to 8man)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R06260", "ec-code": "2.4.1.260", "sbo": "SBO:0000176"}, "metabolites": {"dolp_c": 1.0, "m6mpdol_c": -1.0, "h_c": 1.0, "dolmanp_c": -1.0, "m7mpdol_c": 1.0}, "id": "RC06260", "gene_reaction_rule": "WBGene00022629"}, {"subsystem": "N-Glycan biosynthesis", "name": "dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase (8man to 9man)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R06261", "ec-code": "2.4.1.261", "sbo": "SBO:0000176"}, "metabolites": {"m8mpdol_c": 1.0, "dolp_c": 1.0, "h_c": 1.0, "dolmanp_c": -1.0, "m7mpdol_c": -1.0}, "id": "RC06261", "gene_reaction_rule": "WBGene00007556"}, {"subsystem": "Bacterial digestion", "name": "Bacterial cardiolipin uptake", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"clpn_BAC_e": -1.0, "clpn_BAC_c": 1.0}, "id": "DGR0022", "gene_reaction_rule": ""}, {"subsystem": "Bacterial digestion", "name": "Bacterial cardiolipin degradation (major components)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"pa_BAC_c": 1.0, "h2o_c": -1.0, "clpn_BAC_c": -1.0, "pg_BAC_c": 1.0, "h_c": 1.0}, "id": "DGR0023", "gene_reaction_rule": ""}, {"subsystem": "N-Glycan biosynthesis", "name": "dolichyl-P-Glc:Glc2Man9GlcNAc2-PP-dolichol alpha-1,2-glucosyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R06264", "ec-code": "2.4.1.256", "sbo": "SBO:0000176"}, "metabolites": {"g3m8mpdol_c": 1.0, "dolglcp_c": -1.0, "dolp_c": 1.0, "g2m8mpdol_c": -1.0, "h_c": 1.0}, "id": "RC06264", "gene_reaction_rule": "WBGene00007043"}, {"subsystem": "Bacterial digestion", "name": "Bacterial phosphatidylglycerol degradation", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "3.1.1.4", "sbo": "SBO:0000176"}, "metabolites": {"glyc3p_c": 1.0, "glyc_c": 1.0, "h2o_c": -3.0, "h_c": 3.0, "Rtotal_BAC_c": 2.0, "pg_BAC_c": -1.0}, "id": "DGR0021", "gene_reaction_rule": "WBGene00019747 or WBGene00009801 or WBGene00012319 or WBGene00017026 or WBGene00019229 or WBGene00022233 or WBGene00011423 or WBGene00007419 or WBGene00044468"}, {"subsystem": "Exchange with the environment", "name": "Ascaroside 7 exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"ascr7_e": -1.0}, "id": "EXC0174", "gene_reaction_rule": ""}, {"subsystem": "Methane metabolism", "name": "methanol:hydrogen-peroxide oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00602", "ec-code": ["1.11.1.6", "1.11.1.7"], "sbo": "SBO:0000176"}, "metabolites": {"h2o2_c": -1.0, "h2o_c": 2.0, "fald_c": 1.0, "meoh_c": -1.0}, "id": "RC00602", "gene_reaction_rule": "(WBGene00000830 or WBGene00000831 or WBGene00013220) or (WBGene00021401)"}, {"subsystem": "Histone modification", "name": "acetylhistone sink", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000632"}, "metabolites": {"Naclys_c": -1.0}, "id": "SNK0070", "gene_reaction_rule": ""}, {"subsystem": "Histone modification", "name": "non-methylated histone sink", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000632"}, "metabolites": {"Nlys_c": -1.0}, "id": "SNK0071", "gene_reaction_rule": ""}, {"subsystem": "Glycolysis / Gluconeogenesis (indirect)", "name": "beta-fructose 2,6-bisphosphate sink", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000632"}, "metabolites": {"f26bp_c": -1.0}, "id": "SNK0074", "gene_reaction_rule": ""}, {"subsystem": "Bacterial digestion", "name": "Bacterial uptake", "upper_bound": 1000.0, "lower_bound": -0.1, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"BAC_e": -1.0}, "id": "EXC0050", "gene_reaction_rule": ""}, {"subsystem": "Histidine metabolism", "name": "3-Methylimidazole acetaldehyde:NAD+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R04996", "ec-code": "1.2.1.5", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "3mldz_c": -1.0, "h_c": 2.0, "nad_c": -1.0, "nadh_c": 1.0, "3mlda_c": 1.0}, "id": "RC04996", "gene_reaction_rule": "WBGene00000111"}, {"subsystem": "Pentose and glucuronate interconversions", "name": "gulonate dehydrogenase, endoplasmic reticulum", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01481", "ec-code": "1.1.1.19", "sbo": "SBO:0000176"}, "metabolites": {"nadph_c": -1.0, "nadp_c": 1.0, "glcur_c": -1.0, "h_c": -1.0, "guln_c": 1.0}, "id": "RC01481", "gene_reaction_rule": ""}, {"subsystem": "Pentose phosphate pathway", "name": "Sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glycolaldehyde transferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01641", "ec-code": "2.2.1.1", "sbo": "SBO:0000176"}, "metabolites": {"r5p_c": 1.0, "xu5p-D_c": 1.0, "s7p_c": -1.0, "g3p_c": -1.0}, "id": "RC01641", "gene_reaction_rule": "WBGene00008506"}, {"subsystem": "Transport", "name": "dUDP and dUTP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dudp_m": -1.0, "dutp_c": -1.0, "dutp_m": 1.0, "dudp_c": 1.0}, "id": "TCM0154", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "dTDP and dUDP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dtdp_m": -1.0, "dudp_m": 1.0, "dtdp_c": 1.0, "dudp_c": -1.0}, "id": "TCM0156", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Cholesterol transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"chsterol_m": 1.0, "chsterol_c": -1.0}, "id": "TCM0151", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "dUTP and dCDP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dcdp_m": -1.0, "dutp_m": 1.0, "dutp_c": -1.0, "dcdp_c": 1.0}, "id": "TCM0150", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "dTTP and dCDP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dcdp_m": -1.0, "dttp_m": 1.0, "dttp_c": -1.0, "dcdp_c": 1.0}, "id": "TCM0153", "gene_reaction_rule": ""}, {"subsystem": "Iron metabolism", "name": "protoheme farnesyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R07411", "ec-code": "2.5.1.-", "sbo": "SBO:0000176"}, "metabolites": {"pheme_m": -1.0, "frdp_c": -1.0, "h2o_m": -1.0, "hemeo_m": 1.0, "ppi_m": 1.0}, "id": "RM07411", "gene_reaction_rule": "WBGene00012895"}, {"subsystem": "Iron metabolism", "name": "heme A synthase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R07412", "sbo": "SBO:0000176"}, "metabolites": {"hemea_m": 1.0, "h2o_m": 1.0, "hemeo_m": -1.0, "o2_m": -1.0}, "id": "RM07412", "gene_reaction_rule": "WBGene00011526"}, {"subsystem": "Exchange with the environment", "name": "\"5,6-dihydrouracil\" exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"56dura_e": -1.0}, "id": "EX00429", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Tryptamine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"trypta_e": -1.0}, "id": "EX00398", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Prostaglandin H2 exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"prostgh2_e": -1.0}, "id": "EX00427", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "triacylglycerol exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"tag_e": -1.0}, "id": "EX00422", "gene_reaction_rule": ""}, {"subsystem": "Pyrimidine metabolism", "name": "UMP:diphosphate phospho-alpha-D-ribosyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00966", "ec-code": "2.4.2.9", "sbo": "SBO:0000176"}, "metabolites": {"ura_c": -1.0, "ppi_c": 1.0, "prpp_c": -1.0, "ump_c": 1.0}, "id": "RC00966", "gene_reaction_rule": "WBGene00008131"}, {"subsystem": "Transport", "name": "Trehalose transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"tre_c": -1.0, "tre_e": 1.0}, "id": "TCE5082", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Selenate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"sel_e": -1.0}, "id": "EX05697", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "folate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"fol_e": 1.0, "fol_c": -1.0}, "id": "TCE5084", "gene_reaction_rule": "WBGene00007388"}, {"subsystem": "Exchange with the environment", "name": "4-Hydroxyphenylacetate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"4hphac_e": -1.0}, "id": "EX00642", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "5-Hydroxy-L-tryptophan exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"5htrp_e": -1.0}, "id": "EX00643", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "glucose transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"glc-D_e": 1.0, "glc-D_c": -1.0}, "id": "TCE5085", "gene_reaction_rule": "WBGene00019207"}, {"subsystem": "Pentose phosphate pathway", "name": "2-deoxy-D-ribose 1-phosphate 1,5-phosphomutase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R02749", "ec-code": "5.4.2.7", "sbo": "SBO:0000176"}, "metabolites": {"2dr1p_c": -1.0, "2dr5p_c": 1.0}, "id": "RC02749", "gene_reaction_rule": "WBGene00012803"}, {"subsystem": "Purine metabolism", "name": "Deoxyinosine:orthophosphate ribosyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R02748", "ec-code": "2.4.2.1", "sbo": "SBO:0000176"}, "metabolites": {"din_c": -1.0, "pi_c": -1.0, "2dr1p_c": 1.0, "hxan_c": 1.0}, "id": "RC02748", "gene_reaction_rule": "WBGene00019298"}, {"subsystem": "Glycolysis / Gluconeogenesis", "name": "alpha-D-Glucose 6-phosphate ketol-isomerase (producing beta-D-Fructose 6-phosphate)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R02740", "ec-code": "5.3.1.9", "sbo": "SBO:0000176"}, "metabolites": {"g6p-A_c": -1.0, "f6p_c": 1.0}, "id": "RC02740", "gene_reaction_rule": "WBGene00013597"}, {"subsystem": "Glutathione metabolism", "name": "(5-L-Glutamyl)-L-cysteine 5-glutamyltransferase (cyclizing)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02743", "ec-code": "2.3.2.4", "sbo": "SBO:0000176"}, "metabolites": {"cys-L_c": 1.0, "glucys_c": -1.0, "5oxpro_c": 1.0}, "id": "RC02743", "gene_reaction_rule": "WBGene00016629"}, {"subsystem": "Purine metabolism", "name": "Xanthosine:orthophosphate ribosyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R02297", "ec-code": "2.4.2.1", "sbo": "SBO:0000176"}, "metabolites": {"pi_c": -1.0, "xan_c": 1.0, "r1p_c": 1.0, "xtsn_c": -1.0}, "id": "RC02297", "gene_reaction_rule": "WBGene00019298"}, {"subsystem": "Exchange with the environment", "name": "Molybdate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"mobd_e": -1.0}, "id": "EX06232", "gene_reaction_rule": ""}, {"subsystem": "Nicotinate and nicotinamide metabolism", "name": "Nicotinate D-ribonucleoside:orthophosphate ribosyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R02295", "ec-code": "2.4.2.1", "sbo": "SBO:0000176"}, "metabolites": {"pi_c": 1.0, "nicrns_c": 1.0, "h_c": -1.0, "r1p_c": -1.0, "nac_c": -1.0}, "id": "RC02295", "gene_reaction_rule": "WBGene00019298"}, {"subsystem": "Glycerophospholipid metabolism", "name": "1-Acyl-sn-glycero-3-phosphocholine acylhydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R02746", "R02747"], "ec-code": "3.1.1.5", "sbo": "SBO:0000176"}, "metabolites": {"h_c": 1.0, "h2o_c": -1.0, "lpchol_c": -1.0, "Rtotal_c": 1.0, "g3pc_c": 1.0}, "id": "RC02746", "gene_reaction_rule": "WBGene00022718 or WBGene00007756 or WBGene00010872 or WBGene00010564"}, {"subsystem": "Transport", "name": "Aspartate-glutamate mitochondrial shuttle", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"asp-L_m": -1.0, "glu-L_c": -1.0, "glu-L_m": 1.0, "asp-L_c": 1.0}, "id": "TCM5095", "gene_reaction_rule": ""}, {"subsystem": "Propanoate metabolism", "name": "branched-chain 2-oxo acid dehydrogenase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": ["1.2.4.4", "1.8.1.4", "2.3.1.168"], "sbo": "SBO:0000176"}, "metabolites": {"2obut_m": -1.0, "ppcoa_m": 1.0, "nadh_m": 1.0, "nad_m": -1.0, "coa_m": -1.0, "co2_m": 1.0}, "id": "RMC0133", "gene_reaction_rule": "((WBGene00012713 or WBGene00012799) and WBGene00006518) and WBGene00010794 and WBGene00014054"}, {"subsystem": "Iron-sulfur cluster biosynthesis", "name": "iron-sulfur cluster biosynthesis", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R07460", "ec-code": "2.8.1.7", "sbo": "SBO:0000176"}, "metabolites": {"apoISclustprot_m": -1.0, "ala-L_m": 2.0, "atp_m": -1.0, "h2o_m": -1.0, "ISclustprot_m": 1.0, "pi_m": 1.0, "cys-L_m": -2.0, "adp_m": 1.0, "h_m": 1.0, "fe3_m": -2.0}, "id": "RMC0132", "gene_reaction_rule": "WBGene00015021 and WBGene00012885 and (WBGene00001486 or WBGene00012666) and WBGene00001033 and WBGene00002010  "}, {"subsystem": "Transport", "name": "Dehydroascorbate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dhdascb_c": 1.0, "dhdascb_e": -1.0}, "id": "TCE0591", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "dCMP exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"dcmp_e": -1.0}, "id": "EX00239", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Isocitrate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"icit_c": 1.0, "icit_e": -1.0}, "id": "TCE5329", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "N6,N6,N6-Trimethyl-L-lysine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"tmlys_c": -1.0, "tmlys_e": 1.0}, "id": "TCE5328", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "L-Phenylalanine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"phe-L_e": -1.0, "phe-L_c": 1.0}, "id": "TCE0758", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "6,7-Dihydrobiopterin transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dhbpt_e": 1.0, "dhbpt_c": -1.0}, "id": "TCE5325", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Tetrahydrobiopterin transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"thbpt_e": 1.0, "thbpt_c": -1.0}, "id": "TCE5324", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Dodecanoate (n-C12:0) transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"ddca_c": -1.0, "ddca_e": 1.0}, "id": "TCE5327", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "L-Kynurenine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"Lkynr_e": -1.0, "Lkynr_c": 1.0}, "id": "TCE5326", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Retinal transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"retinal_c": -1.0, "retinal_e": 1.0}, "id": "TCE5321", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "5-Methylthioadenosine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"5mta_c": 1.0, "5mta_e": -1.0}, "id": "TCE5320", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Pyridoxal 5'-phosphate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"pydx5p_e": -1.0, "pydx5p_c": 1.0}, "id": "TCE5323", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "sn-Glycero-3-phosphocholine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"g3pc_e": -1.0, "g3pc_c": 1.0}, "id": "TCE5322", "gene_reaction_rule": ""}, {"subsystem": "Sulfur metabolism", "name": "Thiosulfate oxidation (cytochrome c reducing)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R10151", "sbo": "SBO:0000176"}, "metabolites": {"h2o_m": -5.0, "ficytC_m": -8.0, "tsul_m": -1.0, "h_m": 10.0, "focytC_m": 8.0, "so4_m": 2.0}, "id": "RM10151", "gene_reaction_rule": "WBGene00017121 or WBGene00013854"}, {"subsystem": "Exchange with the environment", "name": "potassium exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"k_e": -1.0}, "id": "EX00238", "gene_reaction_rule": ""}, {"subsystem": "Retinol metabolism", "name": "UDP-glucuronate-retinol glucuronyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02902", "ec-code": "2.4.1.17", "sbo": "SBO:0000176"}, "metabolites": {"retnglc_c": 1.0, "retn_c": -1.0, "udp_c": 1.0, "udpglcur_c": -1.0}, "id": "RC02902", "gene_reaction_rule": "WBGene00015371 or WBGene00016959 or WBGene00017334 or WBGene00018789 or WBGene00019235 or WBGene00019379 or WBGene00007072 or WBGene00020594 or WBGene00020593 or WBGene00020592 or WBGene00019232 or WBGene00019233 or WBGene00008097 or WBGene00013901 or WBGene00007422 or WBGene00013900 or WBGene00019515 or WBGene00007073 or WBGene00019516 or WBGene00007885 or WBGene00007455 or WBGene00007650 or WBGene00016762 or WBGene00015692 or WBGene00015695 or WBGene00015694 or WBGene00021709 or WBGene00013903 or WBGene00011340 or WBGene00021464 or WBGene00018543 or WBGene00007946 or WBGene00009255 or WBGene00044286 or WBGene00017315 or WBGene00017332 or WBGene00017333 or WBGene00017329 or WBGene00013905 or WBGene00017331 or WBGene00017336 or WBGene00017959 or WBGene00008485 or WBGene00008486 or WBGene00021372 or WBGene00015141 or WBGene00011006 or WBGene00015965 or WBGene00007070 or WBGene00013906 or WBGene00011564 or WBGene00015369 or WBGene00018931 or WBGene00020182 or WBGene00012013 or WBGene00011452 or WBGene00011453 or WBGene00009450 or WBGene00011238 or WBGene00013904 or WBGene00007402 or WBGene00018206 or WBGene00010904 or WBGene00015449 or WBGene00015577 or WBGene00008583 or WBGene00015739 or WBGene00019234 or WBGene00020587"}, {"subsystem": "Tryptophan metabolism", "name": "5-Hydroxytryptamine:oxygen oxidoreductase (deaminating) (flavin-containing)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02908", "ec-code": "1.4.3.4", "sbo": "SBO:0000176"}, "metabolites": {"srtn_c": -1.0, "h2o_c": -1.0, "o2_c": -1.0, "5hoxindact_c": 1.0, "h2o2_c": 1.0, "nh4_c": 1.0}, "id": "RC02908", "gene_reaction_rule": "WBGene00000138"}, {"subsystem": "Oxidative phosphorylation", "name": "ATP phosphohydrolase", "upper_bound": 0.0, "lower_bound": 0.0, "annotation": {"kegg.reaction": "R00086", "ec-code": "3.6.3.14", "sbo": "SBO:0000176"}, "metabolites": {"atp_m": 1.0, "h2o_m": 1.0, "h_c": -3.0, "adp_m": -1.0, "h_m": 2.0, "pi_m": -1.0}, "id": "RMC0005", "gene_reaction_rule": "(WBGene00010419 or WBGene00012040) and WBGene00000229 and WBGene00022089 and WBGene00019061 and (WBGene00017982 or WBGene00019880 or WBGene00022582) and WBGene00000230 and WBGene00010960 and (WBGene00000207 or WBGene00000206) and WBGene00022336 and WBGene00007385 and WBGene00011015 and WBGene00011273 and (WBGene00000210 or WBGene00000209)"}, {"subsystem": "Oxidative phosphorylation", "name": "ATP phosphohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00086", "ec-code": "3.6.3.14", "sbo": "SBO:0000176"}, "metabolites": {"atp_m": 1.0, "h2o_m": 1.0, "h_c": -4.0, "adp_m": -1.0, "h_m": 3.0, "pi_m": -1.0}, "id": "RMC0004", "gene_reaction_rule": "(WBGene00010419 or WBGene00012040) and WBGene00000229 and WBGene00022089 and WBGene00019061 and (WBGene00017982 or WBGene00019880 or WBGene00022582) and WBGene00000230 and WBGene00010960 and (WBGene00000207 or WBGene00000206) and WBGene00022336 and WBGene00007385 and WBGene00011015 and WBGene00011273 and (WBGene00000210 or WBGene00000209)"}, {"subsystem": "Oxidative phosphorylation", "name": "NADH:ubiquinone oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02163", "ec-code": ["1.6.5.3", "1.6.99.3"], "sbo": "SBO:0000176"}, "metabolites": {"nad_m": 1.0, "q_m": -1.0, "qh2_m": 1.0, "nadh_m": -1.0, "h_c": -1.0}, "id": "RMC0007", "gene_reaction_rule": "(WBGene00010959 and WBGene00010961 and WBGene00010966 and WBGene00010963 and WBGene00010967 and WBGene00010957 and WBGene00010958) and (WBGene00009992 and (WBGene00001520 or WBGene00006463) and WBGene00020417 and WBGene00003831 and WBGene00021562 and WBGene00012376 and WBGene00020636 and WBGene00003061 and WBGene00021839 and WBGene00009051) and (WBGene00009294 and WBGene00013406 and WBGene00007880 and WBGene00013308 and WBGene00009740 and WBGene00021849 and WBGene00021800 and WBGene00019401 and (WBGene00018151 or WBGene00013237) and WBGene00016393) and (WBGene00009712 and WBGene00007684 and WBGene00012166 and WBGene00016118 and WBGene00014086 and WBGene00008414 and WBGene00013094 and WBGene00015810 and WBGene00010326 and WBGene00022169 and WBGene00018361)"}, {"subsystem": "Oxidative phosphorylation", "name": "NADH:ubiquinone oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02163", "ec-code": ["1.6.5.3", "1.6.99.3"], "sbo": "SBO:0000176"}, "metabolites": {"q_m": -1.0, "nadh_m": -1.0, "nad_m": 1.0, "h_m": -5.0, "qh2_m": 1.0, "h_c": 4.0}, "id": "RMC0006", "gene_reaction_rule": "(WBGene00010959 and WBGene00010961 and WBGene00010966 and WBGene00010963 and WBGene00010967 and WBGene00010957 and WBGene00010958) and (WBGene00009992 and (WBGene00001520 or WBGene00006463) and WBGene00020417 and WBGene00003831 and WBGene00021562 and WBGene00012376 and WBGene00020636 and WBGene00003061 and WBGene00021839 and WBGene00009051) and (WBGene00009294 and WBGene00013406 and WBGene00007880 and WBGene00013308 and WBGene00009740 and WBGene00021849 and WBGene00021800 and WBGene00019401 and (WBGene00018151 or WBGene00013237) and WBGene00016393) and (WBGene00009712 and WBGene00007684 and WBGene00012166 and WBGene00016118 and WBGene00014086 and WBGene00008414 and WBGene00013094 and WBGene00015810 and WBGene00010326 and WBGene00022169 and WBGene00018361)"}, {"subsystem": "Citrate cycle (TCA cycle)", "name": "isocitrate hydro-lyase (cis-aconitate-forming)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": ["R01325", "R01900"], "ec-code": "4.2.1.3", "sbo": "SBO:0000176"}, "metabolites": {"cit_m": -1.0, "icit_m": 1.0}, "id": "RMC0001", "gene_reaction_rule": "WBGene00000041"}, {"subsystem": "Citrate cycle (TCA cycle)", "name": "2-oxoglutarate dehydrogenase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R00621", "R03316", "R02570", "R07618"], "ec-code": ["1.2.4.2", "2.3.1.61", "1.8.1.4"], "sbo": "SBO:0000176"}, "metabolites": {"succoa_m": 1.0, "akg_m": -1.0, "co2_m": 1.0, "nad_m": -1.0, "coa_m": -1.0, "nadh_m": 1.0}, "id": "RMC0003", "gene_reaction_rule": "(WBGene00020679 and WBGene00014098) and WBGene00020950 and WBGene00010794"}, {"subsystem": "Cysteine and methionine metabolism", "name": "3-sulfinopyruvate hydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"3snpyr_m": -1.0, "so3_m": 1.0, "h_m": 1.0, "h2o_m": -1.0, "pyr_m": 1.0}, "id": "RMC0009", "gene_reaction_rule": ""}, {"subsystem": "Oxidative phosphorylation", "name": "NADH:ubiquinone oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02163", "ec-code": ["1.6.5.3", "1.6.99.3"], "sbo": "SBO:0000176"}, "metabolites": {"nad_m": 1.0, "q_m": -1.0, "h_m": -1.0, "nadh_m": -1.0, "qh2_m": 1.0}, "id": "RMC0008", "gene_reaction_rule": "(WBGene00010959 and WBGene00010961 and WBGene00010966 and WBGene00010963 and WBGene00010967 and WBGene00010957 and WBGene00010958) and (WBGene00009992 and (WBGene00001520 or WBGene00006463) and WBGene00020417 and WBGene00003831 and WBGene00021562 and WBGene00012376 and WBGene00020636 and WBGene00003061 and WBGene00021839 and WBGene00009051) and (WBGene00009294 and WBGene00013406 and WBGene00007880 and WBGene00013308 and WBGene00009740 and WBGene00021849 and WBGene00021800 and WBGene00019401 and (WBGene00018151 or WBGene00013237) and WBGene00016393) and (WBGene00009712 and WBGene00007684 and WBGene00012166 and WBGene00016118 and WBGene00014086 and WBGene00008414 and WBGene00013094 and WBGene00015810 and WBGene00010326 and WBGene00022169 and WBGene00018361)"}, {"subsystem": "Vitamin B12 metabolism", "name": "ATP:cob(I)alamin Co-beta-adenosyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01492", "ec-code": "2.5.1.17", "sbo": "SBO:0000176"}, "metabolites": {"atp_m": -1.0, "pppi_m": 1.0, "h_m": -1.0, "cbl1_m": -1.0, "adocbl_m": 1.0}, "id": "RM01492", "gene_reaction_rule": "WBGene00016144  or WBGene00013577"}, {"subsystem": "Arginine and proline metabolism", "name": "L-Proline:NADP+ 5-oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01251", "ec-code": "1.5.1.2", "sbo": "SBO:0000176"}, "metabolites": {"nadph_m": -1.0, "h_m": -2.0, "nadp_m": 1.0, "1pyr5c_m": -1.0, "pro-L_m": 1.0}, "id": "RM01251", "gene_reaction_rule": "WBGene00010924 or WBGene00018904"}, {"subsystem": "Arginine and proline metabolism", "name": "L-proline:(acceptor) oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R10507", "ec-code": "1.5.-.-", "sbo": "SBO:0000176"}, "metabolites": {"fad_m": -1.0, "h_m": 1.0, "fadh2_m": 1.0, "pro-L_m": -1.0, "1pyr5c_m": 1.0}, "id": "RM01253", "gene_reaction_rule": "WBGene00007197"}, {"subsystem": "Exchange with the environment", "name": "N-Carbamoyl-beta-alanine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"cala_e": -1.0}, "id": "EX02642", "gene_reaction_rule": ""}, {"subsystem": "Primary bile acid biosynthesis", "name": "Choloyl-CoA:taurine N-choloyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03720", "ec-code": "2.3.1.65", "sbo": "SBO:0000176"}, "metabolites": {"cholcoa_c": -1.0, "coa_c": 1.0, "tchola_c": 1.0, "taur_c": -1.0}, "id": "RC03720", "gene_reaction_rule": "WBGene00007857 or WBGene00020989 or WBGene00020258 or WBGene00019404"}, {"subsystem": "Exchange with the environment", "name": "3-(4-Hydroxyphenyl)pyruvate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"34hpp_e": -1.0}, "id": "EX01179", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "3-Phospho-D-glycerate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"3pg_e": -1.0}, "id": "EX00197", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Retinol transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"retinol_c": 1.0, "retinol_e": -1.0}, "id": "TCE0374", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "linoleic acid (all cis C18:2) n-6 transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"lnlc_e": -1.0, "lnlc_c": 1.0}, "id": "TCE0376", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "3-mercaptolactate-cysteine disulfide transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"mercplaccys_c": -1.0, "mercplaccys_e": 1.0}, "id": "TCE0370", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Formate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"for_e": -1.0, "for_c": 1.0}, "id": "TCE1202", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Hydrogen peroxide transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"h2o2_c": 1.0, "h2o2_e": -1.0}, "id": "TCE0379", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "proton transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"h_e": 1.0, "h_c": -1.0}, "id": "TCE5505", "gene_reaction_rule": ""}, {"subsystem": "Retinol metabolism", "name": "retinol:NAD+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R02124", "ec-code": ["1.1.1.1", "1.1.1.105"], "sbo": "SBO:0000176"}, "metabolites": {"retinal_c": 1.0, "retinol_c": -1.0, "nadh_c": 1.0, "h_c": 1.0, "nad_c": -1.0}, "id": "RC02124", "gene_reaction_rule": "(WBGene00019240 or (WBGene00017060 or WBGene00010790 or WBGene00010791)) or (WBGene00000982 or WBGene00000967)"}, {"subsystem": "Nicotinate and nicotinamide metabolism", "name": "Nicotinate-nucleotide:pyrophosphate phosphoribosyltransferase (carboxylating)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03348", "ec-code": "2.4.2.19", "sbo": "SBO:0000176"}, "metabolites": {"nicrnt_c": 1.0, "ppi_c": 1.0, "quln_c": -1.0, "h_c": -2.0, "co2_c": 1.0, "prpp_c": -1.0}, "id": "RC03348", "gene_reaction_rule": "WBGene00011559"}, {"subsystem": "Transport", "name": "1-Methylnicotinamide transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"h2o_c": -1.0, "atp_c": -1.0, "1mncam_e": 1.0, "h_c": 1.0, "adp_c": 1.0, "1mncam_c": -1.0, "pi_c": 1.0}, "id": "TCE0574", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "chloride uptake with hydroxide exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"cl_e": -2.0, "cl_c": 2.0, "oh1_e": 1.0, "oh1_c": -1.0}, "id": "TCE5501", "gene_reaction_rule": ""}, {"subsystem": "Tryptophan metabolism", "name": "Indole-3-acetaldehyde:NAD+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02678", "ec-code": "1.2.1.3", "sbo": "SBO:0000176"}, "metabolites": {"h2o_m": -1.0, "id3acald_m": -1.0, "ind3ac_m": 1.0, "nadh_m": 1.0, "nad_m": -1.0, "h_m": 2.0}, "id": "RM02678", "gene_reaction_rule": "(WBGene00000107 or WBGene00000108 or WBGene00000110) or WBGene00000115"}, {"subsystem": "Inositol phosphate metabolism", "name": "1-Phosphatidyl-1D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03435", "ec-code": "3.1.4.11", "sbo": "SBO:0000176"}, "metabolites": {"dag_pl_c": 1.0, "h2o_c": -1.0, "mi145p_c": 1.0, "h_c": 1.0, "pail45p_c": -1.0}, "id": "RC03435", "gene_reaction_rule": "WBGene00004036 or WBGene00004037 or WBGene00004038 or WBGene00004039 or WBGene00001177"}, {"subsystem": "Cysteine and methionine metabolism", "name": "5-methylthioribose-1-phosphate isomerase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R04420", "ec-code": "5.3.1.23", "sbo": "SBO:0000176"}, "metabolites": {"5mdr1p_c": -1.0, "5mdru1p_c": 1.0}, "id": "RC04420", "gene_reaction_rule": "WBGene00007236"}, {"subsystem": "Inositol phosphate metabolism", "name": "D-myo-Inositol 1,3,4,5-tetrakisphosphate 5-phosphohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03430", "ec-code": "3.1.3.56", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "pi_c": 1.0, "mi134p_c": 1.0, "mi1345p_c": -1.0}, "id": "RC03430", "gene_reaction_rule": "WBGene00015278 or WBGene00002146"}, {"subsystem": "Inositol phosphate metabolism", "name": "ATP:1D-myo-inositol-1,4,5-trisphosphate 3-phosphotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R03433", "ec-code": "2.7.1.127", "sbo": "SBO:0000176"}, "metabolites": {"mi1345p_c": 1.0, "mi145p_c": -1.0, "adp_c": 1.0, "atp_c": -1.0, "h_c": 1.0}, "id": "RC03433", "gene_reaction_rule": "WBGene00002979"}, {"subsystem": "Aminoacyl-tRNA biosynthesis", "name": "glycine:tRNA(Gly) ligase (AMP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03654", "ec-code": "6.1.1.14", "sbo": "SBO:0000176"}, "metabolites": {"glytrna_c": 1.0, "atp_c": -1.0, "ppi_c": 1.0, "trnagly_c": -1.0, "amp_c": 1.0, "gly_c": -1.0}, "id": "RC03654", "gene_reaction_rule": "WBGene00001744"}, {"subsystem": "Aminoacyl-tRNA biosynthesis", "name": "L-Histidine:tRNA(His) ligase (AMP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03655", "ec-code": "6.1.1.21", "sbo": "SBO:0000176"}, "metabolites": {"histrna_c": 1.0, "atp_c": -1.0, "ppi_c": 1.0, "trnahis_c": -1.0, "amp_c": 1.0, "his-L_c": -1.0}, "id": "RC03655", "gene_reaction_rule": "WBGene00002001"}, {"subsystem": "Aminoacyl-tRNA biosynthesis", "name": "L-Isoleucine:tRNA(Ile) ligase (AMP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03656", "ec-code": "6.1.1.5", "sbo": "SBO:0000176"}, "metabolites": {"iletrna_c": 1.0, "trnaile_c": -1.0, "atp_c": -1.0, "ppi_c": 1.0, "amp_c": 1.0, "ile-L_c": -1.0}, "id": "RC03656", "gene_reaction_rule": "WBGene00002152"}, {"subsystem": "Aminoacyl-tRNA biosynthesis", "name": "L-Leucine:tRNA(Leu) ligase (AMP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03657", "ec-code": "6.1.1.4", "sbo": "SBO:0000176"}, "metabolites": {"leutrna_c": 1.0, "atp_c": -1.0, "ppi_c": 1.0, "leu-L_c": -1.0, "amp_c": 1.0, "trnaleu_c": -1.0}, "id": "RC03657", "gene_reaction_rule": "WBGene00003073"}, {"subsystem": "Aminoacyl-tRNA biosynthesis", "name": "L-Cysteine:tRNA(Cys) ligase (AMP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03650", "ec-code": "6.1.1.16", "sbo": "SBO:0000176"}, "metabolites": {"cystrna_c": 1.0, "atp_c": -1.0, "ppi_c": 1.0, "amp_c": 1.0, "cys-L_c": -1.0, "trnacys_c": -1.0}, "id": "RC03650", "gene_reaction_rule": "WBGene00000800"}, {"subsystem": "Aminoacyl-tRNA biosynthesis", "name": "L-Glutamine:tRNA(Gln) ligase (AMP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03652", "ec-code": "6.1.1.18", "sbo": "SBO:0000176"}, "metabolites": {"glntrna_c": 1.0, "atp_c": -1.0, "gln-L_c": -1.0, "trnagln_c": -1.0, "ppi_c": 1.0, "amp_c": 1.0}, "id": "RC03652", "gene_reaction_rule": "WBGene00001336"}, {"subsystem": "Transport", "name": "2-Oxobutanoate transport (mitochondria/cytosol)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"2obut_c": 1.0, "2obut_m": -1.0}, "id": "TCM5058", "gene_reaction_rule": ""}, {"subsystem": "Carnitine shuttle", "name": "Carnitine-acylcarnitine translocase (vacccrn)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"vacccrn_c": -1.0, "vacccrn_m": 1.0}, "id": "TCM5057", "gene_reaction_rule": "WBGene00000996 or WBGene00008320"}, {"subsystem": "Ascaroside biosynthesis", "name": "ascr-coa (ascr3) hydrolysis", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"h_c": 1.0, "h2o_c": -1.0, "coa_c": 1.0, "ascr3coa_c": -1.0, "ascr3_c": 1.0}, "id": "RCC0230", "gene_reaction_rule": ""}, {"subsystem": "Carnitine shuttle", "name": "Carnitine-acylcarnitine translocase (stcrn)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"stcrn_m": 1.0, "stcrn_c": -1.0}, "id": "TCM5055", "gene_reaction_rule": "WBGene00000996 or WBGene00008320"}, {"subsystem": "Carnitine shuttle", "name": "Carnitine-acylcarnitine translocase (odecrn)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"odecrn_c": -1.0, "odecrn_m": 1.0}, "id": "TCM5054", "gene_reaction_rule": "WBGene00000996 or WBGene00008320"}, {"subsystem": "Aminoacyl-tRNA biosynthesis", "name": "L-Lysine:tRNALys ligase (AMP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03658", "ec-code": "6.1.1.6", "sbo": "SBO:0000176"}, "metabolites": {"trnalys_c": -1.0, "atp_c": -1.0, "ppi_c": 1.0, "lys-L_c": -1.0, "amp_c": 1.0, "lystrna_c": 1.0}, "id": "RC03658", "gene_reaction_rule": "WBGene00002238"}, {"subsystem": "Aminoacyl-tRNA biosynthesis", "name": "L-Methionine:tRNAMet ligase (AMP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03659", "ec-code": "6.1.1.10", "sbo": "SBO:0000176"}, "metabolites": {"mettrna_c": 1.0, "atp_c": -1.0, "ppi_c": 1.0, "amp_c": 1.0, "trnamet_c": -1.0, "met-L_c": -1.0}, "id": "RC03659", "gene_reaction_rule": "WBGene00003415 or WBGene00013678"}, {"subsystem": "Carnitine shuttle", "name": "Carnitine-acylcarnitine translocase (eicostetcrn)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"eicostetcrn_m": 1.0, "eicostetcrn_c": -1.0}, "id": "TCM5051", "gene_reaction_rule": "WBGene00000996 or WBGene00008320"}, {"subsystem": "Ascaroside biosynthesis", "name": "ascr-coa (ascr1) hydrolysis", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"ascr1_c": 1.0, "h2o_c": -1.0, "ascr1coa_c": -1.0, "coa_c": 1.0, "h_c": 1.0}, "id": "RCC0231", "gene_reaction_rule": ""}, {"subsystem": "Histone modification", "name": "Protein N6,N6,N6-trimethyl-L-lysine demand", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"Ntmelys_c": -1.0}, "id": "DMN0057", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Phosphatidylserine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"ps_e": -1.0}, "id": "EX02737", "gene_reaction_rule": ""}, {"subsystem": "Citrate cycle (TCA cycle)", "name": "Isocitrate:NAD+ oxidoreductase (decarboxylating)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00709", "ec-code": "1.1.1.41", "sbo": "SBO:0000176"}, "metabolites": {"nad_m": -1.0, "nadh_m": 1.0, "icit_m": -1.0, "akg_m": 1.0, "co2_m": 1.0}, "id": "RM00709", "gene_reaction_rule": "WBGene00009664 and WBGene00007993 and (WBGene00009440 or WBGene00016266)"}, {"subsystem": "Transport", "name": "dATP and ADP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"adp_m": -1.0, "datp_c": -1.0, "adp_c": 1.0, "datp_m": 1.0}, "id": "TCM0214", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "taurocholic acid exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"tchola_e": -1.0}, "id": "EX05122", "gene_reaction_rule": ""}, {"subsystem": "Inositol phosphate metabolism", "name": "phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R04513", "ec-code": "3.1.3.67", "sbo": "SBO:0000176"}, "metabolites": {"pail345p_c": -1.0, "h2o_c": -1.0, "pi_c": 1.0, "pail45p_c": 1.0}, "id": "RC04513", "gene_reaction_rule": "WBGene00000913"}, {"subsystem": "Exchange with the environment", "name": "Ethanol exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"etoh_e": -1.0}, "id": "EX00469", "gene_reaction_rule": ""}, {"subsystem": "Propanoate metabolism", "name": "methylmalonyl-CoA carboxy-lyase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R05373", "ec-code": "4.1.1.9", "sbo": "SBO:0000176"}, "metabolites": {"mmcoa-S_m": -1.0, "ppcoa_m": 1.0, "h_m": -1.0, "co2_m": 1.0}, "id": "RM05373", "gene_reaction_rule": "WBGene00009439"}, {"subsystem": "Primary bile acid biosynthesis", "name": "3beta-hydroxy-Delta5-C27-steroid oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R08723", "ec-code": "1.1.1.181", "sbo": "SBO:0000176"}, "metabolites": {"h_c": 1.0, "nadh_c": 1.0, "xol25one_c": 1.0, "nad_c": -1.0, "xoltri25_c": -1.0}, "id": "RC08723", "gene_reaction_rule": "WBGene00012394 or WBGene00022498 or WBGene00022616"}, {"subsystem": "Glycerolipid metabolism", "name": "acyl-CoA:sn-glycerol-3-phosphate 1-O-acyltransferase (acting on Rtotal group)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00851", "ec-code": "2.3.1.15", "sbo": "SBO:0000176"}, "metabolites": {"Rtotalcoa_c": -1.0, "coa_c": 1.0, "glyc3p_c": -1.0, "alpa_pl_c": 1.0}, "id": "RC00851", "gene_reaction_rule": "WBGene00017261 or (WBGene00018657 or WBGene00011106)"}, {"subsystem": "Glutathione metabolism", "name": "glutathione dehydrogenase (ascorbate)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01108", "ec-code": "1.8.5.1", "sbo": "SBO:0000176"}, "metabolites": {"dhdascb_c": -1.0, "gthrd_c": -2.0, "ascb-L_c": 1.0, "gthox_c": 1.0}, "id": "RC01108", "gene_reaction_rule": ""}, {"subsystem": "Galactose metabolism", "name": "Raffinose galactohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01103", "ec-code": "3.2.1.22", "sbo": "SBO:0000176"}, "metabolites": {"raffin_c": -1.0, "sucr_c": 1.0, "h2o_c": -1.0, "gal_c": 1.0}, "id": "RC01103", "gene_reaction_rule": "WBGene00011095"}, {"subsystem": "Galactose metabolism", "name": "Lactose galactohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01100", "ec-code": "3.2.1.23", "sbo": "SBO:0000176"}, "metabolites": {"lcts_c": -1.0, "h2o_c": -1.0, "gal_c": 1.0, "glc-D_c": 1.0}, "id": "RC01100", "gene_reaction_rule": "WBGene00011832"}, {"subsystem": "Galactose metabolism", "name": "melibiose galactohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01101", "ec-code": "3.2.1.22", "sbo": "SBO:0000176"}, "metabolites": {"melib_c": -1.0, "gal_c": 1.0, "h2o_c": -1.0, "glc-D_c": 1.0}, "id": "RC01101", "gene_reaction_rule": "WBGene00011095"}, {"subsystem": "Exchange with the environment", "name": "N-Methylhistamine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"mhista_e": -1.0}, "id": "EX05127", "gene_reaction_rule": ""}, {"subsystem": "Galactose metabolism", "name": "UDP-glucose 4-epimerase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00291", "ec-code": "5.1.3.2", "sbo": "SBO:0000176"}, "metabolites": {"udpgal_c": 1.0, "udpg_c": -1.0}, "id": "RC00291", "gene_reaction_rule": "WBGene00008132"}, {"subsystem": "Amino sugar and nucleotide sugar metabolism", "name": "UDP-glucose 4,6-hydro-lyase (UDP-4-dehydro-6-deoxy-D-glucose-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00293", "ec-code": "4.2.1.76", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": 1.0, "udpg_c": -1.0, "udp4k6dg_c": 1.0}, "id": "RC00293", "gene_reaction_rule": "WBGene00015298"}, {"subsystem": "Glycolysis / Gluconeogenesis", "name": "ATP:D-fructose-6-phosphate 1-phosphotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R04779", "ec-code": "2.7.1.11", "sbo": "SBO:0000176"}, "metabolites": {"h_c": 1.0, "fdp_c": 1.0, "adp_c": 1.0, "atp_c": -1.0, "f6p_c": -1.0}, "id": "RC04779", "gene_reaction_rule": "WBGene00008230 or WBGene00022199"}, {"subsystem": "Glycerophospholipid metabolism", "name": "Phsophatidyl-L-serine carboxy-lyase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02055", "ec-code": "4.1.1.65", "sbo": "SBO:0000176"}, "metabolites": {"co2_c": 1.0, "pe_c": 1.0, "h_c": -1.0, "ps_c": -1.0}, "id": "RC02055", "gene_reaction_rule": "WBGene00015159"}, {"subsystem": "Transport", "name": "Choline transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"chol_c": -1.0, "chol_m": 1.0}, "id": "TCM0196", "gene_reaction_rule": ""}, {"subsystem": "Selenocompound metabolism", "name": "Selenomethionine methanethiol-lyase (deaminating)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R04770", "ec-code": "4.4.1.1", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "2obut_c": 1.0, "nh4_c": 1.0, "metsel_c": 1.0, "h_c": 1.0, "selmeth_c": -1.0}, "id": "RC04770", "gene_reaction_rule": "WBGene00007533 or WBGene00009048 or WBGene00022856"}, {"subsystem": "Folate biosynthesis", "name": "2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl) dihydropteridine triphosphate lyase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R04286", "ec-code": "4.2.3.12", "sbo": "SBO:0000176"}, "metabolites": {"pppi_c": 1.0, "6pthp_c": 1.0, "ahdt_c": -1.0}, "id": "RC04286", "gene_reaction_rule": "WBGene00015010"}, {"subsystem": "Transport", "name": "Mixed transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"fad_m": 1.0, "succ_c": 1.0, "fum_c": -1.0, "fadh2_m": -1.0}, "id": "TCM1071", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Uridine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"uri_e": -1.0}, "id": "EX00299", "gene_reaction_rule": ""}, {"subsystem": "Amino sugar and nucleotide sugar metabolism", "name": "N-Acetyl-D-glucosamine-6-phosphate amidohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02059", "ec-code": "3.5.1.25", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "acgam6p_c": -1.0, "ac_c": 1.0, "gam6p_c": 1.0}, "id": "RC02059", "gene_reaction_rule": "WBGene00010308"}, {"subsystem": "Transport", "name": "2-Oxoadipate transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"2oxoadp_m": -1.0, "2oxoadp_c": 1.0}, "id": "TCM1073", "gene_reaction_rule": ""}, {"subsystem": "Miscellaneous", "name": "V-ATPase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "3.6.3.14", "sbo": "SBO:0000176"}, "metabolites": {"h_pumped_c": 1.0, "h2o_c": -1.0, "pi_c": 1.0, "adp_c": 1.0, "atp_c": -1.0}, "id": "RCC0250", "gene_reaction_rule": "WBGene00013025 and (WBGene00006921 or WBGene00004959) and WBGene00006920 and WBGene00010130 and WBGene00006917 and WBGene00006918 and WBGene00006919 and (WBGene00018698 or WBGene00020507) and (WBGene00006916 or WBGene00006914 or WBGene00006915 or WBGene00006768) and (WBGene00006911 or WBGene00006910 or WBGene00006913 or WBGene00006912) and WBGene00009882 and WBGene00021952"}, {"subsystem": "Glycine, serine and threonine metabolism", "name": "glycine:oxygen oxidoreductase (deaminating)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00366", "ec-code": "1.4.3.3", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "h2o_c": -1.0, "gly_c": -1.0, "h2o2_c": 1.0, "glx_c": 1.0, "nh4_c": 1.0}, "id": "RC00366", "gene_reaction_rule": "WBGene00022076"}, {"subsystem": "Glycine, serine and threonine metabolism", "name": "aminoacetone:oxygen oxidoreductase(deaminating)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02529", "ec-code": "1.4.3.4", "sbo": "SBO:0000176"}, "metabolites": {"aact_m": -1.0, "h2o_m": -1.0, "o2_m": -1.0, "nh4_m": 1.0, "mthgxl_m": 1.0, "h2o2_m": 1.0}, "id": "RM02529", "gene_reaction_rule": "WBGene00000138"}, {"subsystem": "Exchange with the environment", "name": "\"7-alpha,25-Dihydroxycholesterol\" exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"xoltri25_e": -1.0}, "id": "EX15520", "gene_reaction_rule": ""}, {"subsystem": "Terpenoid backbone biosynthesis", "name": "geranylgeranyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"ec-code": ["2.5.1.59", "2.5.1.60"], "sbo": "SBO:0000176"}, "metabolites": {"protSger_c": 1.0, "protCys_c": -1.0, "ttc-ggdp_c": -1.0, "ppi_c": 1.0}, "id": "RCC0032", "gene_reaction_rule": "WBGene00013002 or (WBGene00019778 and WBGene00015099)"}, {"subsystem": "Fructose and mannose metabolism", "name": "D-mannose-6-phosphate aldose-ketose-isomerase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01819", "ec-code": "5.3.1.8", "sbo": "SBO:0000176"}, "metabolites": {"man6p_c": -1.0, "f6p_c": 1.0}, "id": "RC01819", "gene_reaction_rule": "WBGene00015464 or WBGene00014013"}, {"subsystem": "N-Glycan biosynthesis", "name": "dehydrodolichol phosphate phosphatase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "pi_c": 1.0, "dedolp_c": -1.0, "dedol_c": 1.0}, "id": "RCC0030", "gene_reaction_rule": ""}, {"subsystem": "N-Glycan biosynthesis", "name": "Polyprenol reductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"nadp_c": 1.0, "nadph_c": -1.0, "h_c": -1.0, "dolichol_c": 1.0, "dedol_c": -1.0}, "id": "RCC0031", "gene_reaction_rule": "WBGene00007102"}, {"subsystem": "Purine metabolism", "name": "5-phosphoribosylamine:diphosphate phospho-alpha-D-ribosyltransferase (glutamate-amidating)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01072", "ec-code": "2.4.2.14", "sbo": "SBO:0000176"}, "metabolites": {"pram_c": 1.0, "h2o_c": -1.0, "gln-L_c": -1.0, "glu-L_c": 1.0, "ppi_c": 1.0, "prpp_c": -1.0}, "id": "RC01072", "gene_reaction_rule": "WBGene00011407"}, {"subsystem": "N-Glycan biosynthesis", "name": "GDP-mannose:glycolipid 1,2-alpha-D-mannosyltransferase; GDP-mannose:glycolipid 1,2-alpha-D-mannosyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R06127", "R06128"], "ec-code": "2.4.1.131", "sbo": "SBO:0000176"}, "metabolites": {"m2mpdol_c": -1.0, "gdpmann_c": -2.0, "gdp_c": 2.0, "h_c": 2.0, "m4mpdol_c": 1.0}, "id": "RCC0037", "gene_reaction_rule": "WBGene00015162"}, {"subsystem": "Glycolysis / Gluconeogenesis", "name": "beta-D-fructose-1,6-bisphosphate D-glyceraldehyde-3-phosphate-lyase (glycerone-phosphate-forming)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01070", "ec-code": "4.1.2.13", "sbo": "SBO:0000176"}, "metabolites": {"dhap_c": 1.0, "fdp_c": -1.0, "g3p_c": 1.0}, "id": "RC01070", "gene_reaction_rule": "WBGene00017166 or WBGene00011474"}, {"subsystem": "N-Glycan biosynthesis", "name": "mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase (acting on nm4masn)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R05984", "ec-code": "3.2.1.114", "sbo": "SBO:0000176"}, "metabolites": {"nm3masn_c": 1.0, "h2o_c": -1.0, "man_c": 1.0, "nm4masn_c": -1.0}, "id": "RCC0038", "gene_reaction_rule": "WBGene00010284"}, {"subsystem": "N-Glycan biosynthesis", "name": "mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase (acting on nm3masn)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R05984", "ec-code": "3.2.1.114", "sbo": "SBO:0000176"}, "metabolites": {"nm3masn_c": -1.0, "h2o_c": -1.0, "nm2masn_c": 1.0, "man_c": 1.0}, "id": "RCC0039", "gene_reaction_rule": "WBGene00010284"}, {"subsystem": "Tryptophan metabolism", "name": "L-Tryptophan,tetrahydrobiopterin:oxygen oxidoreductase (5-hydroxylating) (Dihydrobiopterin forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01814", "ec-code": "1.14.16.4", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "h2o_c": 1.0, "thbpt_c": -1.0, "trp-L_c": -1.0, "5htrp_c": 1.0, "dhbpt_c": 1.0}, "id": "RC01814", "gene_reaction_rule": "WBGene00006600"}, {"subsystem": "Tyrosine metabolism", "name": "L-Tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating) (Dihydrobiopterin forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01815", "ec-code": "1.14.16.2", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "h2o_c": 1.0, "thbpt_c": -1.0, "tyr-L_c": -1.0, "dhbpt_c": 1.0, "34dhphe_c": 1.0}, "id": "RC01815", "gene_reaction_rule": "WBGene00000296"}, {"subsystem": "Tryptophan metabolism", "name": "anthranilate 3-monooxygenase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01816", "ec-code": "1.14.16.3", "sbo": "SBO:0000176"}, "metabolites": {"anth_c": -1.0, "h2o_c": 1.0, "o2_c": -1.0, "3hanthrn_c": 1.0, "thbpt_c": -1.0, "h_c": -1.0, "dhbpt_c": 1.0}, "id": "RC01816", "gene_reaction_rule": ""}, {"subsystem": "Terpenoid backbone biosynthesis", "name": "(2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate cistransferase (adding 10-55 isopentenyl units)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R05556", "ec-code": "2.5.1.87", "sbo": "SBO:0000176"}, "metabolites": {"ppi_c": 19.0, "ipdp_c": -19.0, "frdp_c": -1.0, "dedoldp_c": 1.0}, "id": "RC05556", "gene_reaction_rule": "WBGene00044025"}, {"subsystem": "Porphyrin and chlorophyll metabolism", "name": "Fe(II):oxygen oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00078", "ec-code": "1.16.3.1", "sbo": "SBO:0000176"}, "metabolites": {"fe2_c": -4.0, "o2_c": -1.0, "h2o_c": 2.0, "h_c": -4.0, "fe3_c": 4.0}, "id": "RC00078", "gene_reaction_rule": "WBGene00001500 or WBGene00001501"}, {"subsystem": "Sulfur metabolism", "name": "sulfur dioxygenase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00781", "ec-code": "1.13.11.18", "sbo": "SBO:0000176"}, "metabolites": {"h2o_m": -1.0, "so3_m": 1.0, "h_m": 2.0, "s_m": -1.0, "o2_m": -1.0}, "id": "RM00781", "gene_reaction_rule": "WBGene00007886"}, {"subsystem": "Exchange with the environment", "name": "Succinic semialdehyde exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"sucsal_e": -1.0}, "id": "EX00232", "gene_reaction_rule": ""}, {"subsystem": "Miscellaneous", "name": "vATPase-pumped proton demand", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"h_pumped_c": -1.0}, "id": "DMN0100", "gene_reaction_rule": ""}, {"subsystem": "Arginine and proline metabolism", "name": "L-Proline,2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01252", "ec-code": "1.14.11.2", "sbo": "SBO:0000176"}, "metabolites": {"akg_c": -1.0, "o2_c": -1.0, "4hpro-LT_c": 1.0, "co2_c": 1.0, "succ_c": 1.0, "pro-L_c": -1.0}, "id": "RC01252", "gene_reaction_rule": "WBGene00015773 or WBGene00077688 or WBGene00001077 or WBGene00004025 or WBGene00004026 or WBGene00012815"}, {"subsystem": "Ubiquinone and other terpenoid-quinone biosynthesis", "name": "methyltransferase COQ3", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R08781", "ec-code": "2.1.1.114", "sbo": "SBO:0000176"}, "metabolites": {"q9_m": 1.0, "amet_m": -1.0, "h_m": 1.0, "ahcys_m": 1.0, "2npmhobq_m": -1.0}, "id": "RM08781", "gene_reaction_rule": "WBGene00000763"}, {"subsystem": "Exchange with the environment", "name": "beta-Alanine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"ala-B_e": -1.0}, "id": "EX00099", "gene_reaction_rule": ""}, {"subsystem": "Valine, leucine and isoleucine degradation", "name": "(S)-3-Hydroxyisobutyryl-CoA hydro-lyase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R04224", "ec-code": "4.2.1.17", "sbo": "SBO:0000176"}, "metabolites": {"3hibutcoa_m": 1.0, "h2o_m": -1.0, "2mp2coa_m": -1.0}, "id": "RM04224", "gene_reaction_rule": "(WBGene00001155 or WBGene00001156) or (WBGene00020347 or WBGene00001150) or WBGene00001152"}, {"subsystem": "Transport", "name": "5-Hydroxyindoleacetate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"5hoxindoa_c": -1.0, "5hoxindoa_e": 1.0}, "id": "TCE7572", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Sulfite exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"so3_e": -1.0}, "id": "EX00094", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "L-Cysteine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"cys-L_e": -1.0}, "id": "EX00097", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Glycerol 3-phosphate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"glyc3p_e": -1.0}, "id": "EX00093", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "L-Lysine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"lys-L_c": 1.0, "lys-L_e": -1.0}, "id": "TCE1184", "gene_reaction_rule": ""}, {"subsystem": "Alanine, aspartate and glutamate metabolism", "name": "L-Alanine:2-oxoglutarate aminotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00258", "ec-code": "2.6.1.2", "sbo": "SBO:0000176"}, "metabolites": {"pyr_m": 1.0, "ala-L_m": -1.0, "glu-L_m": 1.0, "akg_m": -1.0}, "id": "RM00258", "gene_reaction_rule": "WBGene00016333"}, {"subsystem": "Exchange with the environment", "name": "Iodide exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"i_e": -1.0}, "id": "EX00708", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "L-Arabinose exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"arab-L_e": -1.0}, "id": "EX00259", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "gluconate uptake", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"glcn_e": -1.0}, "id": "EX00257", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Superoxide anion exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"o2s_e": -1.0}, "id": "EX00704", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "riboflavin exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"ribflv_e": -1.0}, "id": "EX00255", "gene_reaction_rule": ""}, {"subsystem": "Arginine and proline metabolism", "name": "L-ornithine carboxy-lyase (putrescine-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00670", "ec-code": "4.1.1.17", "sbo": "SBO:0000176"}, "metabolites": {"ptrc_c": 1.0, "co2_c": 1.0, "orn_c": -1.0, "h_c": -1.0}, "id": "RC00670", "gene_reaction_rule": "WBGene00018764 or WBGene00003844"}, {"subsystem": "Exchange with the environment", "name": "Ascaroside 10 exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"ascr10_e": -1.0}, "id": "EXC0162", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Ascaroside 1 exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"ascr1_e": -1.0}, "id": "EXC0163", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Ascaroside 3 exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"ascr3_e": -1.0}, "id": "EXC0160", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "pyridoxal exchange/defecation", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"pydx_e": -1.0}, "id": "EX00250", "gene_reaction_rule": ""}, {"subsystem": "Purine metabolism", "name": "ITP sink", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000632"}, "metabolites": {"itp_c": -1.0}, "id": "SNK0045", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "thiamine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"thm_e": -1.0}, "id": "EX00378", "gene_reaction_rule": ""}, {"subsystem": "Glycerophospholipid metabolism", "name": "sn-glycerol 3-phosphate:quinone oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R08657", "ec-code": "1.1.5.3", "sbo": "SBO:0000176"}, "metabolites": {"q_m": -1.0, "dhap_c": 1.0, "glyc3p_c": -1.0, "qh2_m": 1.0}, "id": "RM08657", "gene_reaction_rule": "WBGene00012031 or WBGene00013049"}, {"subsystem": "Transport", "name": "Phosphatidylserine transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"h2o_c": -1.0, "ps_c": -1.0, "atp_c": -1.0, "ps_m": 1.0, "h_c": 1.0, "adp_c": 1.0, "pi_c": 1.0}, "id": "TCM2002", "gene_reaction_rule": ""}, {"subsystem": "Sphingolipid metabolism", "name": "D-Glucosyl-N-acylsphingosine glucohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01498", "ec-code": "3.2.1.45", "sbo": "SBO:0000176"}, "metabolites": {"gluside_ce_c": -1.0, "crm_ce_c": 1.0, "h2o_c": -1.0, "glc-D_c": 1.0}, "id": "RC01498", "gene_reaction_rule": "(WBGene00019965 or WBGene00013670) or (WBGene00016335 or WBGene00016340 or WBGene00008706 or WBGene00021160)"}, {"subsystem": "Purine metabolism", "name": "GTP phosphohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00335", "ec-code": "3.6.5.5", "sbo": "SBO:0000176"}, "metabolites": {"gtp_m": -1.0, "h_m": 1.0, "h2o_m": -1.0, "gdp_m": 1.0, "pi_m": 1.0}, "id": "RM00335", "gene_reaction_rule": "WBGene00001093 or WBGene00001134"}, {"subsystem": "Sphingolipid metabolism", "name": "N-Acylsphingosine amidohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01494", "ec-code": "3.5.1.23", "sbo": "SBO:0000176"}, "metabolites": {"crm_ce_c": -1.0, "h2o_c": -1.0, "sphings_ce_c": 1.0, "Rtotal_c": 1.0}, "id": "RC01494", "gene_reaction_rule": "WBGene00020947 or (WBGene00009192 or WBGene00010769)"}, {"subsystem": "Sphingolipid metabolism", "name": "ATP:ceramide 1-phosphotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01495", "ec-code": "2.7.1.138", "sbo": "SBO:0000176"}, "metabolites": {"crmp_ce_c": 1.0, "crm_ce_c": -1.0, "adp_c": 1.0, "atp_c": -1.0, "h_c": 1.0}, "id": "RC01495", "gene_reaction_rule": "WBGene00020398"}, {"subsystem": "Sphingolipid metabolism", "name": "Acyl-CoA:sphingosine N-acyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01496", "ec-code": "2.3.1.24", "sbo": "SBO:0000176"}, "metabolites": {"crm_ce_c": 1.0, "Rtotalcoa_c": -1.0, "coa_c": 1.0, "sphings_ce_c": -1.0, "h_c": 1.0}, "id": "RC01496", "gene_reaction_rule": "WBGene00002043 or WBGene00002044 or WBGene00006505"}, {"subsystem": "Sphingolipid metabolism", "name": "UDP-glucose:N-acylsphingosine D-glucosyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01497", "ec-code": "2.4.1.80", "sbo": "SBO:0000176"}, "metabolites": {"gluside_ce_c": 1.0, "crm_ce_c": -1.0, "udp_c": 1.0, "udpg_c": -1.0, "h_c": 1.0}, "id": "RC01497", "gene_reaction_rule": "WBGene00011517 or WBGene00017625 or WBGene00019127"}, {"subsystem": "Transport", "name": "Phosphatidylethanolamine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"pe_m": 1.0, "pe_c": -1.0}, "id": "TCM2004", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "dGTP and ATP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"atp_m": -1.0, "dgtp_c": -1.0, "dgtp_m": 1.0, "atp_c": 1.0}, "id": "TCM0143", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "dGDP and ATP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"atp_m": -1.0, "dgdp_c": -1.0, "dgdp_m": 1.0, "atp_c": 1.0}, "id": "TCM0140", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "L-Glutamine transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"gln-L_m": 1.0, "gln-L_c": -1.0}, "id": "TCM0141", "gene_reaction_rule": ""}, {"subsystem": "Glycolysis / Gluconeogenesis", "name": "(S)-Lactate:NAD+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00703", "ec-code": "1.1.1.27", "sbo": "SBO:0000176"}, "metabolites": {"lac-L_c": -1.0, "nadh_c": 1.0, "pyr_c": 1.0, "nad_c": -1.0, "h_c": 1.0}, "id": "RC00703", "gene_reaction_rule": "WBGene00002262"}, {"subsystem": "Terpenoid backbone biosynthesis", "name": "Dimethylallyl-diphosphate:isopentenyl-diphosphate dimethylallyltranstransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01658", "ec-code": "2.5.1.1", "sbo": "SBO:0000176"}, "metabolites": {"dmpp_c": -1.0, "ppi_c": 1.0, "ipdp_c": -1.0, "grdp_c": 1.0}, "id": "RC01658", "gene_reaction_rule": "WBGene00011058"}, {"subsystem": "Transport", "name": "Glycine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"gly_m": 1.0, "gly_c": -1.0}, "id": "TCM0145", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "dTDP and ATP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"atp_m": -1.0, "dtdp_m": 1.0, "dtdp_c": -1.0, "atp_c": 1.0}, "id": "TCM0148", "gene_reaction_rule": ""}, {"subsystem": "One carbon pool by folate", "name": "5,10-Methenyltetrahydrofolate 5-hydrolase (decyclizing)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01655", "ec-code": "3.5.4.9", "sbo": "SBO:0000176"}, "metabolites": {"h_c": 1.0, "h2o_c": -1.0, "methf_c": -1.0, "10fthf_c": 1.0}, "id": "RC01655", "gene_reaction_rule": "WBGene00019492 or WBGene00000929"}, {"subsystem": "Exchange with the environment", "name": "Xylitol exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"xylt_e": -1.0}, "id": "EX00379", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Phenethylamine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"peamn_e": -1.0}, "id": "EX05332", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Selenomethionine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"selmeth_e": -1.0}, "id": "EX05335", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Thymine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"thym_e": -1.0, "thym_c": 1.0}, "id": "TCE0518", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "(S)-3-Methyl-2-oxopentanoate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"3mop_e": -1.0}, "id": "EX00671", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "sn-Glycero-3-phosphocholine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"g3pc_e": -1.0}, "id": "EX00670", "gene_reaction_rule": ""}, {"subsystem": "Aminoacyl-tRNA biosynthesis", "name": "L-Aspartate:tRNA(Asp) ligase (AMP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R05577", "ec-code": "6.1.1.12", "sbo": "SBO:0000176"}, "metabolites": {"ppi_m": 1.0, "atp_m": -1.0, "asptrna_m": 1.0, "asp-L_m": -1.0, "trnaasp_m": -1.0, "amp_m": 1.0}, "id": "RM05577", "gene_reaction_rule": "WBGene00001095"}, {"subsystem": "Aminoacyl-tRNA biosynthesis", "name": "L-glutamate:tRNA(Glu) ligase (AMP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R05578", "ec-code": "6.1.1.17", "sbo": "SBO:0000176"}, "metabolites": {"trnaglu_m": -1.0, "ppi_m": 1.0, "glu-L_m": -1.0, "atp_m": -1.0, "glutrna_m": 1.0, "amp_m": 1.0}, "id": "RM05578", "gene_reaction_rule": "WBGene00001338"}, {"subsystem": "Exchange with the environment", "name": "Ornithine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"orn_e": -1.0}, "id": "EX00077", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "UTP exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"utp_e": -1.0}, "id": "EX00075", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Phosphoenolpyruvate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"pep_e": -1.0}, "id": "EX00074", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "L-Methionine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"met-L_e": -1.0}, "id": "EX00073", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "L-Ascorbate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"ascb-L_e": -1.0}, "id": "EX00072", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "L-Phenylalanine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"phe-L_e": -1.0}, "id": "EX00079", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "L-Tryptophan exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"trp-L_e": -1.0}, "id": "EX00078", "gene_reaction_rule": ""}, {"subsystem": "Histidine metabolism", "name": "imidazolonepropionase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02288", "ec-code": "3.5.2.7", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "4izp_c": -1.0, "h_c": 1.0, "forglu_c": 1.0}, "id": "RC02288", "gene_reaction_rule": "WBGene00020436"}, {"subsystem": "Carnitine shuttle", "name": "Acyl-CoA:L-carnitine O-acyltransferase II (Fatty acyl [C17:iso] CoA)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "2.3.1.21", "sbo": "SBO:0000176"}, "metabolites": {"coa_m": -1.0, "fa17p0isocoa_m": 1.0, "crn_m": 1.0, "fa17p0isocrn_m": -1.0}, "id": "RMC0122", "gene_reaction_rule": "WBGene00011122"}, {"subsystem": "Carnitine shuttle", "name": "Acyl-CoA:L-carnitine O-acyltransferase II (Fatty acyl [C9:iso] CoA)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "2.3.1.21", "sbo": "SBO:0000176"}, "metabolites": {"coa_m": -1.0, "fa9p0isocoa_m": 1.0, "crn_m": 1.0, "fa9p0isocrn_m": -1.0}, "id": "RMC0123", "gene_reaction_rule": "WBGene00011122"}, {"subsystem": "Carnitine shuttle", "name": "Acyl-CoA:L-carnitine O-acyltransferase II (cis-11,12-methyleneoctadecanoyl-CoA)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "2.3.1.21", "sbo": "SBO:0000176"}, "metabolites": {"coa_m": -1.0, "fa19c11crn_m": -1.0, "crn_m": 1.0, "fa19c11coa_m": 1.0}, "id": "RMC0120", "gene_reaction_rule": "WBGene00011122"}, {"subsystem": "Carnitine shuttle", "name": "Acyl-CoA:L-carnitine O-acyltransferase II (Fatty acyl [C15:iso] CoA)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "2.3.1.21", "sbo": "SBO:0000176"}, "metabolites": {"fa15p0isocrn_m": -1.0, "coa_m": -1.0, "fa15p0isocoa_m": 1.0, "crn_m": 1.0}, "id": "RMC0121", "gene_reaction_rule": "WBGene00011122"}, {"subsystem": "Transport", "name": "D-Xylose transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"xyl-D_e": -1.0, "xyl-D_c": 1.0}, "id": "TCE1298", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Phosphatidylserine (bacteria) transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"h2o_c": -1.0, "ps_BAC_c": 1.0, "atp_c": -1.0, "ps_BAC_e": -1.0, "h_c": 1.0, "adp_c": 1.0, "pi_c": 1.0}, "id": "TCE0699", "gene_reaction_rule": ""}, {"subsystem": "Histidine metabolism", "name": "formimidoylglutamate deiminase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02286", "ec-code": "3.5.3.13", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "nh4_c": 1.0, "Nforglu_c": 1.0, "h_c": -3.0, "forglu_c": -1.0}, "id": "RC02286", "gene_reaction_rule": "WBGene00000775"}, {"subsystem": "Transport", "name": "dGDP and dADP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dadp_c": 1.0, "dgdp_c": -1.0, "dgdp_m": 1.0, "dadp_m": -1.0}, "id": "TCM0066", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "beta-Alanine transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"h2o_c": -1.0, "atp_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "ala-B_c": -3.0, "pi_c": 1.0, "ala-B_e": 3.0}, "id": "TCE0697", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Phosphatidylethanolamine active export", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"pe_e": 1.0, "h2o_c": -1.0, "atp_c": -1.0, "pe_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "pi_c": 1.0}, "id": "TCE5406", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "L-Cysteate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"Lcyst_c": 1.0, "Lcyst_e": -1.0, "na1_c": 2.0, "na1_e": -2.0, "cl_e": -1.0, "cl_c": 1.0}, "id": "TCE5338", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Dihydroxyacetone phosphate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dhap_c": 1.0, "dhap_e": -1.0}, "id": "TCE5339", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "3-Phospho-D-glycerate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"3pg_e": -1.0, "3pg_c": 1.0}, "id": "TCE5332", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Choline phosphate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"cholp_c": 1.0, "cholp_e": -1.0}, "id": "TCE5333", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "4-Hydroxy-2-quinolinecarboxylic acid transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"kynate_c": 1.0, "kynate_e": -1.0}, "id": "TCE5330", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "D-Glycerate 2-phosphate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"2pg_e": -1.0, "2pg_c": 1.0}, "id": "TCE5331", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "N-Formimidoyl-L-glutamate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"forglu_e": 1.0, "forglu_c": -1.0}, "id": "TCE5336", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Glycerol 3-phosphate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"glyc3p_c": 1.0, "glyc3p_e": -1.0}, "id": "TCE5337", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "3-(4-Hydroxyphenyl)pyruvate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"34hpp_c": 1.0, "34hpp_e": -1.0}, "id": "TCE5334", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "N-Carbamoyl-L-aspartate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"cbasp_c": 1.0, "cbasp_e": -1.0}, "id": "TCE5335", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Xanthine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"xan_e": -1.0, "xan_c": 1.0}, "id": "TCE1185", "gene_reaction_rule": ""}, {"subsystem": "Selenocompound metabolism (indirect)", "name": "3'-Phosphoadenylylselenate + NADPH <=> Adenosine 3',5'-bisphosphate + Selenite + NADP+ + H+", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R04940", "sbo": "SBO:0000176"}, "metabolites": {"selnt_c": 1.0, "nadph_c": -1.0, "3padsel_c": -1.0, "nadp_c": 1.0, "h_c": 1.0, "pap_c": 1.0}, "id": "RC04940", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Fumarate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"fum_c": 1.0, "fum_e": -1.0}, "id": "TCE1186", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Phosphate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"pi_c": 1.0, "pi_e": -1.0}, "id": "TCE1182", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Stachyose exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"stachyose_e": -1.0}, "id": "EX01613", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "L-Histidine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"his-L_e": -1.0, "his-L_c": 1.0}, "id": "TCE1189", "gene_reaction_rule": ""}, {"subsystem": "Histidine metabolism", "name": "4,5-Dihydro-4-oxo-5-imidazolepropanoate hydro-lyase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02914", "ec-code": "4.2.1.49", "sbo": "SBO:0000176"}, "metabolites": {"urcan_c": -1.0, "h2o_c": -1.0, "4izp_c": 1.0}, "id": "RC02914", "gene_reaction_rule": "WBGene00013103"}, {"subsystem": "Aminoacyl-tRNA biosynthesis", "name": "L-Tyrosine:tRNA(Tyr) ligase (AMP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02918", "ec-code": "6.1.1.1", "sbo": "SBO:0000176"}, "metabolites": {"atp_c": -1.0, "ppi_c": 1.0, "tyrtrna_c": 1.0, "tyr-L_c": -1.0, "trnatyr_c": -1.0, "amp_c": 1.0}, "id": "RC02918", "gene_reaction_rule": "WBGene00013677 or WBGene00006968"}, {"subsystem": "Valine, leucine and isoleucine degradation", "name": "2-oxoisovalerate dehydrogenase (acylating; 3-methyl-2-oxobutanoate), mitochondrial", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R07599", "R07600", "R07618", "R02662"], "ec-code": ["1.2.4.4", "1.8.1.4", "2.3.1.168"], "sbo": "SBO:0000176"}, "metabolites": {"3mob_m": -1.0, "ibcoa_m": 1.0, "co2_m": 1.0, "nad_m": -1.0, "coa_m": -1.0, "nadh_m": 1.0}, "id": "RMC0012", "gene_reaction_rule": "((WBGene00012713 or WBGene00012799) and WBGene00006518) and WBGene00010794 and WBGene00014054"}, {"subsystem": "Valine, leucine and isoleucine degradation", "name": "2-oxoisovalerate dehydrogenase (acylating; 3-methyl-2-oxopentanoate), mitochondrial", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R07603", "R07604", "R07618", "R03174"], "ec-code": ["1.2.4.4", "1.8.1.4", "2.3.1.168"], "sbo": "SBO:0000176"}, "metabolites": {"3mop_m": -1.0, "2mbcoa_m": 1.0, "nadh_m": 1.0, "nad_m": -1.0, "coa_m": -1.0, "co2_m": 1.0}, "id": "RMC0013", "gene_reaction_rule": "((WBGene00012713 or WBGene00012799) and WBGene00006518) and WBGene00010794 and WBGene00014054"}, {"subsystem": "Valine, leucine and isoleucine degradation", "name": "2-oxoisovalerate dehydrogenase (acylating; 4-methyl-2-oxopentaoate), mitochondrial", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R07601", "R07602", "R07618", "R04097"], "ec-code": ["1.2.4.4", "1.8.1.4", "2.3.1.168"], "sbo": "SBO:0000176"}, "metabolites": {"co2_m": 1.0, "4mop_m": -1.0, "nadh_m": 1.0, "nad_m": -1.0, "coa_m": -1.0, "ivcoa_m": 1.0}, "id": "RMC0011", "gene_reaction_rule": "((WBGene00012713 or WBGene00012799) and WBGene00006518) and WBGene00010794 and WBGene00014054"}, {"subsystem": "Arginine and proline metabolism", "name": "L-1-Pyrroline-3-hydroxy-5-carboxylate spontaneous conversion to L-4-Hydroxyglutamate semialdehyde, mitochondrial", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"1p3h5c_m": -1.0, "h_m": -1.0, "h2o_m": -1.0, "4hglusa_m": 1.0}, "id": "RMC0016", "gene_reaction_rule": ""}, {"subsystem": "Lysine degradation", "name": "2-Oxoadipate:lipoamde 2-oxidoreductase(decarboxylating and acceptor-succinylating); Glutaryl-CoA:dihydrolipoamide S-succinyltransferase; Enzyme N6-(dihydrolipoyl)lysine + NAD+ <=> Enzyme N6-(lipoyl)lysine + NADH + H+", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R01940", "R02571", "R07618"], "ec-code": ["1.2.4.2", "2.3.1.61", "1.8.1.4"], "sbo": "SBO:0000176"}, "metabolites": {"2oxoadp_m": -1.0, "nadh_m": 1.0, "nad_m": -1.0, "coa_m": -1.0, "glutcoa_m": 1.0, "co2_m": 1.0}, "id": "RMC0014", "gene_reaction_rule": "(WBGene00020679 and WBGene00014098) and WBGene00020950 and WBGene00010794"}, {"subsystem": "Arginine and proline metabolism", "name": "L-glutamate 5-semialdehyde dehydratase, mitochondrial", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"h_m": 1.0, "h2o_m": 1.0, "1pyr5c_m": 1.0, "glu5sa_m": -1.0}, "id": "RMC0015", "gene_reaction_rule": ""}, {"subsystem": "Carnitine shuttle", "name": "Acyl-CoA:L-carnitine O-acyltransferase I (Fatty acyl [C9:iso] CoA)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "2.3.1.21", "sbo": "SBO:0000176"}, "metabolites": {"crn_c": -1.0, "fa9p0isocoa_c": -1.0, "coa_c": 1.0, "fa9p0isocrn_c": 1.0}, "id": "RCC0123", "gene_reaction_rule": "WBGene00012907 or WBGene00021703 or WBGene00019644 or WBGene00008629 or WBGene00020911"}, {"subsystem": "Glycerolipid metabolism", "name": "ATP:acylglycerol 3-phosphotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02757", "ec-code": "2.7.1.94", "sbo": "SBO:0000176"}, "metabolites": {"h_c": 1.0, "alpa_tag_c": 1.0, "mag_c": -1.0, "atp_c": -1.0, "adp_c": 1.0}, "id": "RC02757", "gene_reaction_rule": "WBGene00018674"}, {"subsystem": "Pentose phosphate pathway", "name": "2-Deoxy-D-ribose 5-phosphate + ADP <=> Deoxyribose + ATP", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02750", "ec-code": "2.7.1.15", "sbo": "SBO:0000176"}, "metabolites": {"adp_c": 1.0, "h_c": 1.0, "2dr5p_c": 1.0, "atp_c": -1.0, "drib_c": -1.0}, "id": "RC02750", "gene_reaction_rule": "WBGene00008548"}, {"subsystem": "Exchange with the environment", "name": "Orotidine 5'-phosphate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"orot5p_e": -1.0}, "id": "EX01103", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Leukotriene A4 exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"leuktrA4_e": -1.0}, "id": "EX00909", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "octadecanoate (n-C18:0) transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"ocdca_e": -1.0, "ocdca_c": 1.0}, "id": "TCE0360", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "ATP and dCTP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"atp_m": -1.0, "dctp_m": 1.0, "atp_c": 1.0, "dctp_c": -1.0}, "id": "TCM0149", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "D-Glucosamine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"gam_c": 1.0, "gam_e": -1.0}, "id": "TCE0368", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Vaccenic acid exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"vacc_e": -1.0}, "id": "EXC0135", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "glycolate transport via proton symport, reversible", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"glyclt_c": 1.0, "glyclt_e": -1.0}, "id": "TCE5045", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "trimethylamine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"tma_e": -1.0, "tma_c": 1.0}, "id": "TCE5046", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "cholestenoate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"7a3o4chlstnt_e": -1.0, "7a3o4chlstnt_c": 1.0}, "id": "TCE5040", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Lactose transport via proton symport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"lcts_c": 1.0, "lcts_e": -1.0}, "id": "TCE5041", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "glucuronic acid transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"glcur_e": -1.0, "glcur_c": 1.0}, "id": "TCE5042", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "glucaric acid transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"glcr_e": -1.0, "glcr_c": 1.0}, "id": "TCE5043", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Melibiose exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"melib_e": -1.0}, "id": "EX05402", "gene_reaction_rule": ""}, {"subsystem": "Valine, leucine and isoleucine degradation", "name": "2-methylpropanoyl-CoA:(acceptor) 2,3-oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R02661", "ec-code": ["1.3.99.12", "1.3.99.3"], "sbo": "SBO:0000176"}, "metabolites": {"ibcoa_m": -1.0, "etfox_m": -1.0, "etfrd_m": 1.0, "2mp2coa_m": 1.0}, "id": "RM02661", "gene_reaction_rule": "(WBGene00016943 or WBGene00015894 or WBGene00019433) or WBGene00017874"}, {"subsystem": "Aminoacyl-tRNA biosynthesis", "name": "L-proline:tRNA(Pro) ligase (AMP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03661", "ec-code": "6.1.1.15", "sbo": "SBO:0000176"}, "metabolites": {"atp_c": -1.0, "trnapro_c": -1.0, "ppi_c": 1.0, "protrna_c": 1.0, "amp_c": 1.0, "pro-L_c": -1.0}, "id": "RC03661", "gene_reaction_rule": "WBGene00004189"}, {"subsystem": "Valine, leucine and isoleucine degradation", "name": "(S)-3-Hydroxy-3-methylglutaryl-CoA hydro-lyase (trans-3-methylglutaconyl-CoA-forming)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R02085", "ec-code": "4.2.1.18", "sbo": "SBO:0000176"}, "metabolites": {"h2o_m": -1.0, "3mgcoa_m": -1.0, "hmgcoa_m": 1.0}, "id": "RM02085", "gene_reaction_rule": "WBGene00001154"}, {"subsystem": "Aminoacyl-tRNA biosynthesis", "name": "L-Threonine:tRNA(Thr) ligase (AMP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03663", "ec-code": "6.1.1.3", "sbo": "SBO:0000176"}, "metabolites": {"atp_c": -1.0, "thrtrna_c": 1.0, "ppi_c": 1.0, "amp_c": 1.0, "thr-L_c": -1.0, "trnathr_c": -1.0}, "id": "RC03663", "gene_reaction_rule": "WBGene00006617"}, {"subsystem": "Aminoacyl-tRNA biosynthesis", "name": "L-Serine:tRNA(Ser) ligase (AMP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03662", "ec-code": "6.1.1.11", "sbo": "SBO:0000176"}, "metabolites": {"ser-L_c": -1.0, "atp_c": -1.0, "ppi_c": 1.0, "sertrna_c": 1.0, "amp_c": 1.0, "trnaser_c": -1.0}, "id": "RC03662", "gene_reaction_rule": "WBGene00005663"}, {"subsystem": "Tryptophan metabolism", "name": "2-Aminomuconate semialdehyde:NAD+ 6-oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03889", "ec-code": "1.2.1.32", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "amuco_c": 1.0, "am6sa_c": -1.0, "h_c": 2.0, "nad_c": -1.0, "nadh_c": 1.0}, "id": "RC03889", "gene_reaction_rule": ""}, {"subsystem": "Carnitine shuttle", "name": "Carnitine-acylcarnitine translocase (arachdcrn)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"arachdcrn_m": 1.0, "arachdcrn_c": -1.0}, "id": "TCM5049", "gene_reaction_rule": "WBGene00000996 or WBGene00008320"}, {"subsystem": "Transport", "name": "2-oxoadipate shuttle (cytosol/mitochondria)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"akg_c": 1.0, "2oxoadp_m": 1.0, "2oxoadp_c": -1.0, "akg_m": -1.0}, "id": "TCM5510", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "atp transport into mitochondria", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"atp_m": 1.0, "pi_c": 1.0, "pi_m": -1.0, "atp_c": -1.0}, "id": "TCM5047", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "cholestenoate transport (cytosol/mitochondria)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"7a3o4chlstnt_m": 1.0, "7a3o4chlstnt_c": -1.0}, "id": "TCM5040", "gene_reaction_rule": ""}, {"subsystem": "Ether lipid metabolism", "name": " 1-acylglycerone phosphate reductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R04360", "ec-code": "1.1.1.101", "sbo": "SBO:0000176"}, "metabolites": {"akgp_c": 1.0, "nadp_c": 1.0, "nadph_c": -1.0, "akdhap_c": -1.0, "h_c": -1.0}, "id": "RC04360", "gene_reaction_rule": ""}, {"subsystem": "Inositol phosphate metabolism", "name": "inositol-1,4-bisphosphate 1-phosphatase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03393", "ec-code": "3.1.3.57", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "mi4p-D_c": 1.0, "mi14p_c": -1.0, "pi_c": 1.0}, "id": "RC03393", "gene_reaction_rule": ""}, {"subsystem": "Inositol phosphate metabolism", "name": "D-myo-Inositol-1,4,5-trisphosphate 5-phosphohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03394", "ec-code": "3.1.3.56", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "pi_c": 1.0, "mi145p_c": -1.0, "mi14p_c": 1.0}, "id": "RC03394", "gene_reaction_rule": "WBGene00015278 or WBGene00002146"}, {"subsystem": "Ether lipid metabolism", "name": "1-Alkyl-2-acyl-sn-glycero-3-phosphate phosphohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R04162", "ec-code": "3.1.3.4", "sbo": "SBO:0000176"}, "metabolites": {"akac2gp_c": -1.0, "h2o_c": -1.0, "pi_c": 1.0, "akac2g_c": 1.0}, "id": "RC04162", "gene_reaction_rule": "WBGene00008749 or WBGene00018756 or WBGene00020895"}, {"subsystem": "Glycine, serine and threonine metabolism", "name": "glycine:lipoylprotein oxidoreductase (decarboxylating and acceptor-aminomethylating)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R03425", "ec-code": "1.4.4.2", "sbo": "SBO:0000176"}, "metabolites": {"co2_m": 1.0, "gly_m": -1.0, "h_m": -1.0, "lpro_m": -1.0, "alpro_m": 1.0}, "id": "RM03425", "gene_reaction_rule": "WBGene00020022 and (WBGene00008354 or WBGene00009918)"}, {"subsystem": "Purine metabolism", "name": "10-Formyltetrahydrofolate:5-phosphoribosyl-5-amino-4-imidazolecarboxamide formyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R04560", "ec-code": "2.1.2.3", "sbo": "SBO:0000176"}, "metabolites": {"aicar_c": -1.0, "fprica_c": 1.0, "10fthf_c": -1.0, "thf_c": 1.0}, "id": "RC04560", "gene_reaction_rule": "WBGene00016957"}, {"subsystem": "Exchange with the environment", "name": "Quinolinate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"quln_e": -1.0}, "id": "EX03722", "gene_reaction_rule": ""}, {"subsystem": "Terpenoid backbone biosynthesis", "name": "ATP:(R)-5-phosphomevalonate phosphotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03245", "ec-code": "2.7.4.2", "sbo": "SBO:0000176"}, "metabolites": {"5pmev_c": -1.0, "5dpmev_c": 1.0, "adp_c": 1.0, "atp_c": -1.0}, "id": "RC03245", "gene_reaction_rule": "WBGene00009335"}, {"subsystem": "Glycerolipid metabolism", "name": "ATP:glycerol 3-phosphotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00847", "ec-code": "2.7.1.30", "sbo": "SBO:0000176"}, "metabolites": {"h_c": 1.0, "glyc3p_c": 1.0, "glyc_c": -1.0, "atp_c": -1.0, "adp_c": 1.0}, "id": "RC00847", "gene_reaction_rule": "WBGene00020007"}, {"subsystem": "Primary bile acid biosynthesis", "name": "3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA:propanoyl-CoA C-acyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03719", "ec-code": "2.3.1.176", "sbo": "SBO:0000176"}, "metabolites": {"cholcoa_c": 1.0, "cholcoaone_c": -1.0, "coa_c": -1.0, "ppcoa_c": 1.0}, "id": "RC03719", "gene_reaction_rule": "(WBGene00013284 or WBGene00003773)"}, {"subsystem": "Primary bile acid biosynthesis", "name": "Choloyl-CoA:glycine N-choloyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03718", "ec-code": "2.3.1.65", "sbo": "SBO:0000176"}, "metabolites": {"cholcoa_c": -1.0, "gchola_c": 1.0, "coa_c": 1.0, "gly_c": -1.0}, "id": "RC03718", "gene_reaction_rule": "WBGene00007857 or WBGene00020989 or WBGene00020258 or WBGene00019404"}, {"subsystem": "Glycerophospholipid metabolism", "name": "sn-Glycerol-3-phosphate:NAD+ 2-oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00842", "ec-code": "1.1.1.8", "sbo": "SBO:0000176"}, "metabolites": {"nad_c": 1.0, "glyc3p_c": 1.0, "dhap_c": -1.0, "h_c": -1.0, "nadh_c": -1.0}, "id": "RC00842", "gene_reaction_rule": "WBGene00009824"}, {"subsystem": "Pentose and glucuronate interconversions", "name": "UDP-glucose:NAD+ 6-oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00286", "ec-code": "1.1.1.22", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "udpglcur_c": 1.0, "h_c": 3.0, "nad_c": -2.0, "nadh_c": 2.0, "udpg_c": -1.0}, "id": "RC00286", "gene_reaction_rule": "WBGene00005022"}, {"subsystem": "Pyrimidine metabolism", "name": "UDP-glucose glucophosphohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00287", "ec-code": "3.6.1.9", "sbo": "SBO:0000176"}, "metabolites": {"ump_c": 1.0, "h2o_c": -1.0, "udpg_c": -1.0, "h_c": 2.0, "g1p_c": 1.0}, "id": "RC00287", "gene_reaction_rule": "WBGene00007753 or WBGene00007755"}, {"subsystem": "Pentose and glucuronate interconversions", "name": "UTP:alpha-D-glucose-1-phosphate uridylyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00289", "ec-code": "2.7.7.9", "sbo": "SBO:0000176"}, "metabolites": {"utp_c": -1.0, "ppi_c": 1.0, "udpg_c": 1.0, "h_c": -1.0, "g1p_c": -1.0}, "id": "RC00289", "gene_reaction_rule": "WBGene00016996 or WBGene00010665"}, {"subsystem": "Cysteine and methionine metabolism", "name": " L-sulfolactate dehydrogenase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R07136", "ec-code": "1.1.1.37", "sbo": "SBO:0000176"}, "metabolites": {"nad_m": -1.0, "sl-L_m": -1.0, "h_m": 1.0, "nadh_m": 1.0, "3spyr_m": 1.0}, "id": "RM07136", "gene_reaction_rule": "WBGene00018491 or WBGene00003162"}, {"subsystem": "Folate biosynthesis", "name": "cyclic pyranopterin phosphate synthase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R09394", "ec-code": "4.1.99.18", "sbo": "SBO:0000176"}, "metabolites": {"ppi_c": 1.0, "gtp_c": -1.0, "cpmp_c": 1.0}, "id": "RC09394", "gene_reaction_rule": "WBGene00009885 or WBGene00009908"}, {"subsystem": "Transport", "name": "\"3,4-Dihydroxy-L-phenylalanine\" transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"34dhphe_e": -1.0, "34dhphe_c": 1.0}, "id": "TCE0710", "gene_reaction_rule": ""}, {"subsystem": "Pyruvate metabolism", "name": "glyoxalase-1", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R02530", "ec-code": "4.4.1.5", "sbo": "SBO:0000176"}, "metabolites": {"mthgxl_m": -1.0, "gthrd_m": -1.0, "lgt-S_m": 1.0}, "id": "RM02530", "gene_reaction_rule": "WBGene00006448"}, {"subsystem": "Ubiquinone and other terpenoid-quinone biosynthesis", "name": "4-hydroxyphenyllactate:NAD+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R03336", "ec-code": "1.1.1.237", "sbo": "SBO:0000176"}, "metabolites": {"34hpl_m": 1.0, "nad_m": 1.0, "h_m": -1.0, "34hpp_m": -1.0, "nadh_m": -1.0}, "id": "RM03336", "gene_reaction_rule": ""}, {"subsystem": "Glycine, serine and threonine metabolism", "name": "L-cystathionine cysteine-lyase (deaminating, 2-oxobutanoate-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01001", "ec-code": "4.4.1.1", "sbo": "SBO:0000176"}, "metabolites": {"cyst-L_c": -1.0, "cys-L_c": 1.0, "h2o_c": -1.0, "2obut_c": 1.0, "nh4_c": 1.0}, "id": "RC01001", "gene_reaction_rule": "WBGene00007533 or WBGene00009048 or WBGene00022856"}, {"subsystem": "Propanoate metabolism", "name": "2-Hydroxybutyrate:NAD+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01000", "ec-code": "1.1.1.27", "sbo": "SBO:0000176"}, "metabolites": {"2obut_c": 1.0, "2hb_c": -1.0, "nadh_c": 1.0, "h_c": 1.0, "nad_c": -1.0}, "id": "RC01000", "gene_reaction_rule": "WBGene00002262"}, {"subsystem": "N-Glycan biosynthesis", "name": "UDPglucose:dolichyl-phosphate beta-D-glucosyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01005", "ec-code": "2.4.1.117", "sbo": "SBO:0000176"}, "metabolites": {"dolglcp_c": 1.0, "dolp_c": -1.0, "udpg_c": -1.0, "udp_c": 1.0}, "id": "RC01005", "gene_reaction_rule": "WBGene00019276"}, {"subsystem": "N-Glycan biosynthesis", "name": "GDPmannose:dolichyl-phosphate O-beta-D-mannosyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01009", "ec-code": "2.4.1.83", "sbo": "SBO:0000176"}, "metabolites": {"gdpmann_c": -1.0, "dolp_c": -1.0, "gdp_c": 1.0, "dolmanp_c": 1.0}, "id": "RC01009", "gene_reaction_rule": "WBGene00022044 or WBGene00009219"}, {"subsystem": "Pyrimidine metabolism", "name": "(S)-dihydroorotate:quinone oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01868", "ec-code": "1.3.5.2", "sbo": "SBO:0000176"}, "metabolites": {"q_m": -1.0, "qh2_m": 1.0, "dhor-S_c": -1.0, "orot_c": 1.0}, "id": "RM01868", "gene_reaction_rule": "WBGene00020932"}, {"subsystem": "Arachidonic acid metabolism", "name": "leukotriene B4 p450", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03866", "ec-code": "1.14.13.30", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "h2o_c": 1.0, "nadp_c": 1.0, "nadph_c": -1.0, "leuktrB4_c": -1.0, "leuktrB4woh_c": 1.0, "h_c": -1.0}, "id": "RC03866", "gene_reaction_rule": "WBGene00007140 or WBGene00016147 or WBGene00021167"}, {"subsystem": "Transport", "name": "Ceramide 1-phosphate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"crmp_ce_c": -1.0, "crmp_ce_e": 1.0}, "id": "TCE5100", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Sphinganine 1-phosphate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"sph1p_ce_e": 1.0, "sph1p_ce_c": -1.0}, "id": "TCE5102", "gene_reaction_rule": ""}, {"subsystem": "Glycine, serine and threonine metabolism", "name": "L-2-Amino-3-oxobutanoic acid decarboxylation", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03758", "sbo": "SBO:0000176"}, "metabolites": {"aact_m": 1.0, "2aobut_m": -1.0, "h_m": -1.0, "co2_m": 1.0}, "id": "RM03758", "gene_reaction_rule": ""}, {"subsystem": "Nicotinate and nicotinamide metabolism", "name": "NAD-dependent histone deacetylase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R10633", "ec-code": "3.5.1.-", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "ncam_c": 1.0, "Naclys_c": -1.0, "ac_adprib_c": 1.0, "nad_c": -1.0, "Nlys_c": 1.0}, "id": "RC10633", "gene_reaction_rule": "WBGene00004800 or WBGene00004801 or WBGene00004802 or WBGene00004803"}, {"subsystem": "Transport", "name": "Globoside transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"gbside_ce_c": -1.0, "gbside_ce_e": 1.0}, "id": "TCE5109", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Sucrose exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"sucr_e": -1.0}, "id": "EX00089", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "L-Tyrosine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"tyr-L_e": -1.0}, "id": "EX00082", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "H+ exchange", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"h_e": -1.0}, "id": "EX00080", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "ITP exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"itp_e": -1.0}, "id": "EX00081", "gene_reaction_rule": ""}, {"subsystem": "Peroxisomal fatty acid beta oxidation", "name": "Lauroyl-CoA oxidase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00388", "ec-code": "1.3.3.6", "sbo": "SBO:0000176"}, "metabolites": {"ddcacoa_c": -1.0, "o2_c": -1.0, "dd2coa_c": 1.0, "h2o2_c": 1.0}, "id": "RCC0167", "gene_reaction_rule": "WBGene00008167 or WBGene00008564 or WBGene00008565 or WBGene00008566 or WBGene00008567 or WBGene00019060 or WBGene00010336"}, {"subsystem": "Vitamin B6 metabolism", "name": "Pyridoxine:oxygen oxidoreductase (deaminating)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01711", "ec-code": "1.4.3.5", "sbo": "SBO:0000176"}, "metabolites": {"pydxn_c": -1.0, "o2_c": -1.0, "pydx_c": 1.0, "h2o2_c": 1.0}, "id": "RC01711", "gene_reaction_rule": "WBGene00018996"}, {"subsystem": "Vitamin B6 metabolism", "name": "Pyridoxamine:oxygen oxidoreductase (deaminating)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01710", "ec-code": "1.4.3.5", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "h2o_c": -1.0, "h2o2_c": 1.0, "pydx_c": 1.0, "pydam_c": -1.0, "nh4_c": 1.0}, "id": "RC01710", "gene_reaction_rule": "WBGene00018996"}, {"subsystem": "Alanine, aspartate and glutamate metabolism", "name": "L-Glutamate:NADP+ oxidoreductase (deaminating)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00248", "ec-code": ["1.4.1.3", "1.4.1.13"], "sbo": "SBO:0000176"}, "metabolites": {"glu-L_m": -1.0, "nadph_m": 1.0, "h2o_m": -1.0, "nadp_m": -1.0, "akg_m": 1.0, "nh4_m": 1.0, "h_m": 1.0}, "id": "RM00248", "gene_reaction_rule": "WBGene00014095"}, {"subsystem": "Arginine and proline metabolism", "name": "N2-Acetyl-L-ornithine amidohydrolase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00669", "ec-code": ["3.5.1.14", "3.5.1.16"], "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "orn_c": 1.0, "ac_c": 1.0, "acorn_c": -1.0}, "id": "RC00669", "gene_reaction_rule": "(WBGene00015509 or WBGene00007507 or WBGene00007508 or WBGene00007509) or WBGene00016657"}, {"subsystem": "Exchange with the environment", "name": "Urate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"urate_e": -1.0}, "id": "EX00366", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Glycine betaine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"glyb_e": -1.0}, "id": "EX00719", "gene_reaction_rule": ""}, {"subsystem": "Arachidonic acid metabolism", "name": "20-Hydroxyeicosatetraenoic acid demand", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"20HETE_c": -1.0}, "id": "DMN0065", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Hexadecanoate (n-C16:0) exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"hdca_e": -1.0}, "id": "EX00249", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "DNA component of bacterial diet exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"dna_BAC_e": -1.0}, "id": "EXC0053", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Taurine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"taur_e": -1.0}, "id": "EX00245", "gene_reaction_rule": ""}, {"subsystem": "Pyrimidine metabolism", "name": "Uridine triphosphate pyrophosphohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00662", "ec-code": "3.6.1.19", "sbo": "SBO:0000176"}, "metabolites": {"ump_c": 1.0, "h2o_c": -1.0, "ppi_c": 1.0, "utp_c": -1.0, "h_c": 1.0}, "id": "RC00662", "gene_reaction_rule": "WBGene00001823"}, {"subsystem": "Alanine, aspartate and glutamate metabolism", "name": "L-glutamate:NAD+ oxidoreductase (deaminating)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00243", "ec-code": "1.4.1.3", "sbo": "SBO:0000176"}, "metabolites": {"glu-L_m": -1.0, "h2o_m": -1.0, "akg_m": 1.0, "nh4_m": 1.0, "nadh_m": 1.0, "nad_m": -1.0, "h_m": 1.0}, "id": "RM00243", "gene_reaction_rule": "WBGene00014095"}, {"subsystem": "Arginine and proline metabolism", "name": "L-Glutamate 5-semialdehyde:NAD+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00245", "ec-code": "1.2.1.88", "sbo": "SBO:0000176"}, "metabolites": {"glu-L_m": 1.0, "h2o_m": -1.0, "glu5sa_m": -1.0, "nadh_m": 1.0, "nad_m": -1.0, "h_m": 2.0}, "id": "RM00245", "gene_reaction_rule": "WBGene00000112"}, {"subsystem": "Exchange with the environment", "name": "Guanine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"gua_e": -1.0}, "id": "EX00242", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Lactose exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"lcts_e": -1.0}, "id": "EX00243", "gene_reaction_rule": ""}, {"subsystem": "Glyoxylate and dicarboxylate metabolism", "name": "hydroxypyruvate decarboxylase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01393", "ec-code": "4.1.1.40", "sbo": "SBO:0000176"}, "metabolites": {"hpyr_c": -1.0, "co2_c": 1.0, "h_c": -1.0, "gcald_c": 1.0}, "id": "RC01393", "gene_reaction_rule": ""}, {"subsystem": "Pentose phosphate pathway", "name": "sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01827", "ec-code": "2.2.1.2", "sbo": "SBO:0000176"}, "metabolites": {"e4p_c": 1.0, "f6p_c": 1.0, "s7p_c": -1.0, "g3p_c": -1.0}, "id": "RC01827", "gene_reaction_rule": "WBGene00021286"}, {"subsystem": "Pyrimidine metabolism", "name": "carbamoyl-phosphate:L-aspartate carbamoyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01397", "ec-code": "2.1.3.2", "sbo": "SBO:0000176"}, "metabolites": {"cbasp_c": 1.0, "cbp_c": -1.0, "pi_c": 1.0, "h_c": 1.0, "asp-L_c": -1.0}, "id": "RC01397", "gene_reaction_rule": "WBGene00004259"}, {"subsystem": "Transport", "name": "Sodium and Selenate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"na1_c": 3.0, "na1_e": -3.0, "sel_c": 1.0, "sel_e": -1.0}, "id": "TCE0346", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "KDO(2)-lipid (A) exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"lipa_BAC_e": -1.0}, "id": "EXC0056", "gene_reaction_rule": ""}, {"subsystem": "Histone modification", "name": "Protein N6,N6-dimethyl-L-lysine sink", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000632"}, "metabolites": {"Ndmelys_c": -1.0}, "id": "SNK0056", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Outer section of lipopolysaccharide (bacteria) exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"outerlps_BAC_e": -1.0}, "id": "EXC0057", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Deoxycytidine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"dcyt_e": -1.0}, "id": "EX00881", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "octadecanoate (n-C18:0) exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"ocdca_e": -1.0}, "id": "EX01530", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Lipopolysaccharide (bacteria) exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"lps_BAC_e": -1.0}, "id": "EXC0055", "gene_reaction_rule": ""}, {"subsystem": "Inositol phosphate metabolism", "name": "phosphatidylinositol 3,5-bisphosphate 3-phosphatase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R10928", "ec-code": "3.1.3.95", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "pi_c": 1.0, "pail35p_c": -1.0, "pail5p_c": 1.0}, "id": "RC10928", "gene_reaction_rule": "WBGene00003475 or WBGene00003476 or WBGene00003478"}, {"subsystem": "Exchange with the environment", "name": "3-Ureidoisobutyrate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"3uib_e": -1.0}, "id": "EX05100", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "L-Isoleucine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"ile-L_e": -1.0}, "id": "EX00407", "gene_reaction_rule": ""}, {"subsystem": "Glycolysis / Gluconeogenesis", "name": "Acetaldehyde:NAD+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00710", "ec-code": "1.2.1.3", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "acald_c": -1.0, "h_c": 2.0, "nad_c": -1.0, "ac_c": 1.0, "nadh_c": 1.0}, "id": "RC00710", "gene_reaction_rule": "(WBGene00000108 or WBGene00000110) or (WBGene00000117 or WBGene00000118)"}, {"subsystem": "Glycolysis / Gluconeogenesis", "name": "Acetaldehyde:NADP+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00711", "ec-code": "1.2.1.5", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "nadp_c": -1.0, "nadph_c": 1.0, "acald_c": -1.0, "h_c": 2.0, "ac_c": 1.0}, "id": "RC00711", "gene_reaction_rule": "WBGene00000111"}, {"subsystem": "Protein modification by hydroxylation", "name": "N-linked-glycopeptide-(N-acetyl-beta-D-glucosaminyl)-L-asparagine amidohydrolase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R08707", "ec-code": "3.5.1.52", "sbo": "SBO:0000176"}, "metabolites": {"pepasp_acgamam_c": -1.0, "h2o_c": -1.0, "pepasp_c": 1.0, "h_c": 1.0, "acBgamam_c": 1.0}, "id": "RC08707", "gene_reaction_rule": "WBGene00010160"}, {"subsystem": "Exchange with the environment", "name": "Urea exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"urea_e": -1.0}, "id": "EX00086", "gene_reaction_rule": ""}, {"subsystem": "Glycine, serine and threonine metabolism", "name": "L-threonine ammonia-lyase (2-oxobutanoate-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00996", "ec-code": "4.3.1.19", "sbo": "SBO:0000176"}, "metabolites": {"thr-L_c": -1.0, "2obut_c": 1.0, "nh4_c": 1.0}, "id": "RC00996", "gene_reaction_rule": "WBGene00010456 or WBGene00021787"}, {"subsystem": "Exchange with the environment", "name": "Acetaldehyde exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"acald_e": -1.0}, "id": "EX00084", "gene_reaction_rule": ""}, {"subsystem": "Nitrogen metabolism", "name": "carbonate hydro-lyase (carbon-dioxide-forming)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R10092", "ec-code": "4.2.1.1", "sbo": "SBO:0000176"}, "metabolites": {"h_e": 1.0, "h2o_e": -1.0, "co2_e": -1.0, "hco3_e": 1.0}, "id": "RE10092", "gene_reaction_rule": "WBGene00000283"}, {"subsystem": "Aminoacyl-tRNA biosynthesis", "name": "L-Asparagine:tRNA(Asn) ligase (AMP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03648", "ec-code": "6.1.1.22", "sbo": "SBO:0000176"}, "metabolites": {"trnaasn_c": -1.0, "atp_c": -1.0, "asn-L_c": -1.0, "ppi_c": 1.0, "amp_c": 1.0, "asntrna_c": 1.0}, "id": "RC03648", "gene_reaction_rule": "WBGene00003815"}, {"subsystem": "Exchange with the environment", "name": "gamma-L-Glutamyl-L-cysteine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"glucys_e": -1.0}, "id": "EX00669", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "L-Glutamine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"gln-L_e": -1.0}, "id": "EX00064", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "L-Serine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"ser-L_e": -1.0}, "id": "EX00065", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Formaldehyde exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"fald_e": -1.0}, "id": "EX00067", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "FMN exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"fmn_e": -1.0}, "id": "EX00061", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "L-Arginine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"arg-L_e": -1.0}, "id": "EX00062", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Thiamine diphosphate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"thmpp_e": -1.0}, "id": "EX00068", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "linoleic acid (all cis C18:2) n-6 exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"lnlc_e": -1.0}, "id": "EX01595", "gene_reaction_rule": ""}, {"subsystem": "Miscellaneous", "name": "electron transfer flavoprotein", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"fad_m": 1.0, "fadh2_m": -1.0, "etfox_m": -1.0, "etfrd_m": 1.0}, "id": "RMC0155", "gene_reaction_rule": ""}, {"subsystem": "Propanoate metabolism", "name": "Propionyl-CoA:carnitine O-propionyltransferase II", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "2.3.1.7", "sbo": "SBO:0000176"}, "metabolites": {"ppcoa_m": 1.0, "coa_m": -1.0, "pcrn_m": -1.0, "crn_m": 1.0}, "id": "RMC0154", "gene_reaction_rule": "WBGene00011122"}, {"subsystem": "Exchange with the environment", "name": "5-Methylthioadenosine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"5mta_e": -1.0}, "id": "EX00170", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Adenosine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"adn_e": -1.0, "adn_c": 1.0}, "id": "TCE0779", "gene_reaction_rule": ""}, {"subsystem": "Ubiquinone and other terpenoid-quinone biosynthesis", "name": "4-Hydroxybenzoyl-CoA hydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01301", "ec-code": "3.1.2.23", "sbo": "SBO:0000176"}, "metabolites": {"coa_m": 1.0, "h_m": 1.0, "h2o_m": -1.0, "4hbz_m": 1.0, "4hbzcoa_m": -1.0}, "id": "RM01301", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "\"7-alpha,27-Dihydroxycholesterol\" transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"xoltri27_c": -1.0, "xoltri27_e": 1.0}, "id": "TCE0777", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "5-Hydroxyindoleacetate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"5hoxindoa_e": -1.0}, "id": "EX05635", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Ornithine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"orn_e": -1.0, "orn_c": 1.0}, "id": "TCE1197", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "L-Threonine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"thr-L_c": 1.0, "thr-L_e": -1.0}, "id": "TCE1194", "gene_reaction_rule": ""}, {"subsystem": "Isoquinoline alkaloid biosynthesis", "name": "Monophenol,L-dopa:oxygen oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02383", "ec-code": "1.14.18.1", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "h2o_c": 1.0, "dopa_c": 1.0, "tym_c": -1.0, "h_c": -1.0, "nad_c": 1.0, "nadh_c": -1.0}, "id": "RC02383", "gene_reaction_rule": "WBGene00015332 or WBGene00010661 or WBGene00009001 or WBGene00016419 or WBGene00021553 or WBGene00022231"}, {"subsystem": "Tyrosine metabolism", "name": "Tyramine:oxygen oxidoreductase (deaminating) (flavin-containing)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02382", "ec-code": "1.4.3.4", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "h2o_c": -1.0, "tym_c": -1.0, "h2o2_c": 1.0, "4hoxpacd_c": 1.0, "nh4_c": 1.0}, "id": "RC02382", "gene_reaction_rule": "WBGene00000138"}, {"subsystem": "Porphyrin and chlorophyll metabolism", "name": "UDP-glucuronate-bilirubin glucuronyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02389", "ec-code": "2.4.1.17", "sbo": "SBO:0000176"}, "metabolites": {"bildglcur_c": 1.0, "udp_c": 2.0, "bilirub_c": -1.0, "udpglcur_c": -2.0}, "id": "RC02389", "gene_reaction_rule": "WBGene00015371 or WBGene00016959 or WBGene00017334 or WBGene00018789 or WBGene00019235 or WBGene00019379 or WBGene00007072 or WBGene00020594 or WBGene00020593 or WBGene00020592 or WBGene00019232 or WBGene00019233 or WBGene00008097 or WBGene00013901 or WBGene00007422 or WBGene00013900 or WBGene00019515 or WBGene00007073 or WBGene00019516 or WBGene00007885 or WBGene00007455 or WBGene00007650 or WBGene00016762 or WBGene00015692 or WBGene00015695 or WBGene00015694 or WBGene00021709 or WBGene00013903 or WBGene00011340 or WBGene00021464 or WBGene00018543 or WBGene00007946 or WBGene00009255 or WBGene00044286 or WBGene00017315 or WBGene00017332 or WBGene00017333 or WBGene00017329 or WBGene00013905 or WBGene00017331 or WBGene00017336 or WBGene00017959 or WBGene00008485 or WBGene00008486 or WBGene00021372 or WBGene00015141 or WBGene00011006 or WBGene00015965 or WBGene00007070 or WBGene00013906 or WBGene00011564 or WBGene00015369 or WBGene00018931 or WBGene00020182 or WBGene00012013 or WBGene00011452 or WBGene00011453 or WBGene00009450 or WBGene00011238 or WBGene00013904 or WBGene00007402 or WBGene00018206 or WBGene00010904 or WBGene00015449 or WBGene00015577 or WBGene00008583 or WBGene00015739 or WBGene00019234 or WBGene00020587"}, {"subsystem": "Transport", "name": "Deoxycytidine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dcyt_c": 1.0, "dcyt_e": -1.0}, "id": "TCE0482", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Thiocyanate transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"tcynt_e": 1.0, "tcynt_c": -1.0}, "id": "TCE0487", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Sodium and Sulfate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"so4_c": 1.0, "na1_c": 2.0, "na1_e": -2.0, "so4_e": -1.0}, "id": "TCE0486", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Ammonium transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"nh4_e": 1.0, "nh4_c": -1.0}, "id": "TCE0484", "gene_reaction_rule": ""}, {"subsystem": "Pentose phosphate pathway (indirect)", "name": "Sedoheptulose 1,7-bisphosphate D-glyceraldehyde-3-phosphate-lyase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01829", "ec-code": "4.1.2.13", "sbo": "SBO:0000176"}, "metabolites": {"e4p_c": 1.0, "dhap_c": 1.0, "s17bp_c": -1.0}, "id": "RC01829", "gene_reaction_rule": "WBGene00017166 or WBGene00011474"}, {"subsystem": "Fatty acid elongation", "name": "hexadecanoyl-CoA:NADP+ trans-2-oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01278", "ec-code": "1.3.1.38", "sbo": "SBO:0000176"}, "metabolites": {"hdd2coa_m": -1.0, "nadph_m": -1.0, "h_m": -1.0, "nadp_m": 1.0, "pmtcoa_m": 1.0}, "id": "RM01278", "gene_reaction_rule": "WBGene00012375 or WBGene00012970"}, {"subsystem": "Exchange with the environment", "name": "N-Acetyl-D-galactosamine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"acgal_e": -1.0}, "id": "EX01132", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "S-Adenosylmethioninamine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"ametam_e": -1.0}, "id": "EX01137", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "(S)-3-Hydroxybutanoate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"S3hb_e": -1.0}, "id": "EX03197", "gene_reaction_rule": ""}, {"subsystem": "Propanoate metabolism", "name": "beta-alanine:2-oxoglutarate aminotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00908", "ec-code": "2.6.1.19", "sbo": "SBO:0000176"}, "metabolites": {"msa_m": 1.0, "glu-L_m": 1.0, "ala-B_m": -1.0, "akg_m": -1.0}, "id": "RM00908", "gene_reaction_rule": "WBGene00001794"}, {"subsystem": "Glycerophospholipid metabolism", "name": "1-Acyl-sn-glycero-3-phosphoethanolamine aldehydohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R03416", "R03417"], "ec-code": "3.1.1.5", "sbo": "SBO:0000176"}, "metabolites": {"acg3pe_c": -1.0, "h2o_c": -1.0, "h_c": 1.0, "Rtotal_c": 1.0, "g3pe_c": 1.0}, "id": "RC03416", "gene_reaction_rule": "WBGene00022718 or WBGene00007756 or WBGene00010564"}, {"subsystem": "Transport", "name": "Sodium and Cholate transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"cholate_e": -1.0, "na1_c": 2.0, "na1_e": -2.0, "cholate_c": 1.0}, "id": "TCE0399", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "D-Ribose transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"rib-D_e": -1.0, "rib-D_c": 1.0}, "id": "TCE0392", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "L-allo-threonine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"athr-L_c": -1.0, "athr-L_e": 1.0}, "id": "TCE5071", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "FMN transport into cytoplasm", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"fmn_e": -1.0, "fmn_c": 1.0}, "id": "TCE5070", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "1-Acyl-sn-glycero-3-phosphoglycerol transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"lpglyc_e": -1.0, "lpglyc_c": 1.0}, "id": "TCE5073", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Selenomethionine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"selmeth_e": -1.0, "selmeth_c": 1.0}, "id": "TCE5072", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "2-Hydroxyphenylacetate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"2hyoxplac_c": -1.0, "2hyoxplac_e": 1.0}, "id": "TCE5075", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "1-Acyl-sn-glycero-3-phosphoserine transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"acg3ps_c": 1.0, "acg3ps_e": -1.0}, "id": "TCE5074", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "2-Phenylacetamide transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"pad_c": -1.0, "pad_e": 1.0}, "id": "TCE5077", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Phenethylamine transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"peamn_e": 1.0, "peamn_c": -1.0}, "id": "TCE5076", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Bacterial ubiquinone uptake", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"q8_e": 1.0, "q8_c": -1.0}, "id": "TCE5079", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "2-Hydroxy-3-phenylpropenoate transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"enphpyr_c": -1.0, "enphpyr_e": 1.0}, "id": "TCE5078", "gene_reaction_rule": ""}, {"subsystem": "Cysteine and methionine metabolism", "name": "2-keto-4-methylthiobutyrate transamination", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R07396", "ec-code": "2.6.1.5", "sbo": "SBO:0000176"}, "metabolites": {"glu-L_c": -1.0, "akg_c": 1.0, "2kmb_c": -1.0, "met-L_c": 1.0}, "id": "RC07396", "gene_reaction_rule": "WBGene00009628"}, {"subsystem": "Cysteine and methionine metabolism", "name": "S-Methyl-5-thio-D-ribulose-1-phosphate hydro-lyase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R07392", "ec-code": "4.2.1.109", "sbo": "SBO:0000176"}, "metabolites": {"dkmpp_c": 1.0, "h2o_c": 1.0, "5mdru1p_c": -1.0}, "id": "RC07392", "gene_reaction_rule": "WBGene00013870"}, {"subsystem": "Retinol metabolism", "name": "retinol dehydrogenase (9-cis,NADH)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R08383", "ec-code": "1.1.-.-", "sbo": "SBO:0000176"}, "metabolites": {"retinal-cis-9_c": 1.0, "nadp_c": -1.0, "nadph_c": 1.0, "h_c": 1.0, "retinol-9-cis_c": -1.0}, "id": "RC08383", "gene_reaction_rule": "(WBGene00010063 or WBGene00000976) or WBGene00007780"}, {"subsystem": "Retinol metabolism", "name": "Palmitoyl-CoA:retinol O-acyltransferase (cis)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R08381", "ec-code": "2.3.1.76", "sbo": "SBO:0000176"}, "metabolites": {"pmtcoa_c": -1.0, "coa_c": 1.0, "retpalm-cis-11_c": 1.0, "retinol-cis-11_c": -1.0}, "id": "RC08381", "gene_reaction_rule": "WBGene00010408"}, {"subsystem": "Retinol metabolism", "name": "all-trans-retinyl ester acylhydrolase, 11-cis-retinol forming", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R08388", "ec-code": "3.1.1.64", "sbo": "SBO:0000176"}, "metabolites": {"retpalm_c": -1.0, "hdca_c": 1.0, "h2o_c": -1.0, "retinol-cis-11_c": 1.0, "h_c": 1.0}, "id": "RC08388", "gene_reaction_rule": "WBGene00018755"}, {"subsystem": "Glycerophospholipid metabolism", "name": "phosphatidylserine synthase 1", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R07377", "ec-code": "2.7.8.-", "sbo": "SBO:0000176"}, "metabolites": {"ser-L_c": -1.0, "pchol_c": -1.0, "ps_c": 1.0, "chol_c": 1.0}, "id": "RC07377", "gene_reaction_rule": "WBGene00013920"}, {"subsystem": "Primary bile acid biosynthesis", "name": "oxysterol 7alpha-hydroxylase (acting on 27-hydroxycholesterol)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R07372", "ec-code": ["1.14.13.100", "1.14.13.17"], "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "h2o_c": 1.0, "nadp_c": 1.0, "nadph_c": -1.0, "xoltri27_c": 1.0, "h_c": -1.0, "xol27oh_c": -1.0}, "id": "RC07372", "gene_reaction_rule": ""}, {"subsystem": "Valine, leucine and isoleucine degradation", "name": "L-Valine:2-oxoglutarate aminotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01214", "ec-code": "2.6.1.42", "sbo": "SBO:0000176"}, "metabolites": {"val-L_m": -1.0, "glu-L_m": 1.0, "akg_m": -1.0, "3mob_m": 1.0}, "id": "RM01214", "gene_reaction_rule": "WBGene00001149 or WBGene00012855"}, {"subsystem": "Nicotinate and nicotinamide metabolism", "name": "NAD+:poly(adenosine diphosphate D-ribose)ADP-D-ribosyltransferase (PARP)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R04176", "ec-code": "2.4.2.30", "sbo": "SBO:0000176"}, "metabolites": {"polyadprib_c": 1.0, "h_c": 1.0, "nad_c": -1.0, "ncam_c": 1.0}, "id": "RC04176", "gene_reaction_rule": "WBGene00004049 or WBGene00004050 or WBGene00004053"}, {"subsystem": "Tryptophan metabolism", "name": "3-Hydroxy-L-kynurenine:2-oxoglutarate aminotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R04171", "ec-code": "2.6.1.7", "sbo": "SBO:0000176"}, "metabolites": {"akg_c": -1.0, "42A3HP24DB_c": 1.0, "hLkynr_c": -1.0, "glu-L_c": 1.0}, "id": "RC04171", "gene_reaction_rule": "WBGene00009232"}, {"subsystem": "Ether lipid metabolism", "name": "Plasmenylethanolamine 2-acylhydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R07379", "ec-code": "3.1.1.4", "sbo": "SBO:0000176"}, "metabolites": {"h_c": 1.0, "h2o_c": -1.0, "alkenac2gpe_c": -1.0, "alken2gpe_c": 1.0, "Rtotal6_c": 1.0}, "id": "RC07379", "gene_reaction_rule": "WBGene00019747 or WBGene00009801 or WBGene00012319 or WBGene00017026 or WBGene00019229 or WBGene00022233 or WBGene00011423 or WBGene00007419 or WBGene00044468"}, {"subsystem": "Glycine, serine and threonine metabolism", "name": "3-Phosphoserine:2-oxoglutarate aminotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R04173", "ec-code": "2.6.1.52", "sbo": "SBO:0000176"}, "metabolites": {"glu-L_c": -1.0, "3php_c": -1.0, "akg_c": 1.0, "pser-L_c": 1.0}, "id": "RC04173", "gene_reaction_rule": "WBGene00009177"}, {"subsystem": "Sphingolipid metabolism", "name": "Sphingomyelin cholinephosphohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02541", "ec-code": "3.1.4.12", "sbo": "SBO:0000176"}, "metabolites": {"cholp_c": 1.0, "h2o_c": -1.0, "sphmyln_ce_c": -1.0, "h_c": 1.0, "crm_ce_c": 1.0}, "id": "RC02541", "gene_reaction_rule": "(WBGene00000211 or WBGene00000212 or WBGene00000213) or WBGene00012105 or WBGene00011037"}, {"subsystem": "Cysteine and methionine metabolism", "name": "L-cysteate:2-oxoglutarate aminotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R02433", "ec-code": "2.6.1.1", "sbo": "SBO:0000176"}, "metabolites": {"3spyr_m": 1.0, "glu-L_m": 1.0, "akg_m": -1.0, "Lcyst_m": -1.0}, "id": "RM02433", "gene_reaction_rule": "WBGene00016652 or WBGene00015778"}, {"subsystem": "Ether lipid metabolism", "name": "alkyl acyl glycerophosphoethanolamine desaturase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R04571", "ec-code": "1.14.99.19", "sbo": "SBO:0000176"}, "metabolites": {"akac2gpe_c": -1.0, "o2_c": -1.0, "h2o_c": 2.0, "nadp_c": 1.0, "nadph_c": -1.0, "h_c": -1.0, "alkenac2gpe_c": 1.0}, "id": "RC04571", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Dopamine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"dopa_e": -1.0}, "id": "EX03758", "gene_reaction_rule": ""}, {"subsystem": "Fructose and mannose metabolism", "name": "D-sorbitol dehydrogenase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00875", "ec-code": "1.1.1.14", "sbo": "SBO:0000176"}, "metabolites": {"h_c": 1.0, "nadh_c": 1.0, "fru_c": 1.0, "nad_c": -1.0, "sbt-D_c": -1.0}, "id": "RC00875", "gene_reaction_rule": "WBGene00011003 or WBGene00011004"}, {"subsystem": "Purine metabolism", "name": "ATP:dAMP phosphotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01547", "ec-code": "2.7.4.3", "sbo": "SBO:0000176"}, "metabolites": {"dadp_c": 1.0, "damp_c": -1.0, "adp_c": 1.0, "atp_c": -1.0}, "id": "RC01547", "gene_reaction_rule": "WBGene00008458 or (WBGene00009531 or WBGene00014058 or WBGene00002879)"}, {"subsystem": "Glyoxylate and dicarboxylate metabolism", "name": "Glycolate:oxygen 2-oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00475", "ec-code": "1.1.3.15", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "glyclt_c": -1.0, "glx_c": 1.0, "h2o2_c": 1.0}, "id": "RC00475", "gene_reaction_rule": "WBGene00018286"}, {"subsystem": "Arginine and Proline metabolism", "name": "D-4-Hydroxy-2-oxoglutarate glyoxylate-lyase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00471", "ec-code": "4.1.3.16", "sbo": "SBO:0000176"}, "metabolites": {"pyr_c": 1.0, "glx_c": 1.0, "4h2oglt_c": -1.0}, "id": "RC00471", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Sodium and Sulfate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"so4_c": 1.0, "na1_c": 3.0, "na1_e": -3.0, "so4_e": -1.0}, "id": "TCE0622", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Peptidyl-L-lysine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"peplys_c": 1.0, "peplys_e": -1.0}, "id": "TCE0825", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "\"5,6,7,8-Tetrahydrofolate\" and hydroxide ion transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"oh1_c": -1.0, "thf_e": -1.0, "thf_c": 1.0, "oh1_e": 1.0}, "id": "TCE0621", "gene_reaction_rule": ""}, {"subsystem": "Vitamin B6 metabolism", "name": "Pyridoxine 5-phosphate:oxygen oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00278", "ec-code": "1.4.3.5", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "pydx5p_c": 1.0, "pdx5p_c": -1.0, "h2o2_c": 1.0}, "id": "RC00278", "gene_reaction_rule": "WBGene00018996"}, {"subsystem": "Vitamin B6 metabolism", "name": "Pyridoxamine-5-phosphate:oxygen oxidoreductase (deaminating)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00277", "ec-code": "1.4.3.5", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "h2o_c": -1.0, "pydx5p_c": 1.0, "h2o2_c": 1.0, "pyam5p_c": -1.0, "nh4_c": 1.0}, "id": "RC00277", "gene_reaction_rule": "WBGene00018996"}, {"subsystem": "Reactive oxygen species degradation", "name": "superoxide:superoxide oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00275", "ec-code": "1.15.1.1", "sbo": "SBO:0000176"}, "metabolites": {"o2s_c": -2.0, "o2_c": 1.0, "h_c": -2.0, "h2o2_c": 1.0}, "id": "RC00275", "gene_reaction_rule": "WBGene00004930 or WBGene00004933 or WBGene00007036"}, {"subsystem": "Glutathione metabolism", "name": "glutathione:hydrogen-peroxide oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00274", "ec-code": "1.11.1.9", "sbo": "SBO:0000176"}, "metabolites": {"h2o2_c": -1.0, "h2o_c": 2.0, "gthrd_c": -2.0, "gthox_c": 1.0}, "id": "RC00274", "gene_reaction_rule": "WBGene00009165 or WBGene00011045 or WBGene00007517 or WBGene00022377 or WBGene00007516 or WBGene00019846 or WBGene00018850"}, {"subsystem": "Riboflavin metabolism", "name": "riboflavin-5-phosphate phosphohydrolase (acid optimum)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00548", "ec-code": "3.1.3.2", "sbo": "SBO:0000176"}, "metabolites": {"ribflv_e": 1.0, "fmn_e": -1.0, "h2o_e": -1.0, "pi_e": 1.0}, "id": "RE00548", "gene_reaction_rule": "WBGene00022770"}, {"subsystem": "Glycine, serine and threonine metabolism", "name": "L-Serine:pyruvate aminotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00585", "ec-code": "2.6.1.51", "sbo": "SBO:0000176"}, "metabolites": {"ser-L_c": -1.0, "hpyr_c": 1.0, "pyr_c": -1.0, "ala-L_c": 1.0}, "id": "RC00585", "gene_reaction_rule": "WBGene00011767"}, {"subsystem": "Pyruvate metabolism", "name": "(R)-Lactate:ferricytochrome-c 2-oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00197", "ec-code": "1.1.2.4", "sbo": "SBO:0000176"}, "metabolites": {"ficytC_m": -2.0, "pyr_m": 1.0, "h_m": 2.0, "lac-D_m": -1.0, "focytC_m": 2.0}, "id": "RM00197", "gene_reaction_rule": "WBGene00009334 and (WBGene00017121 or WBGene00013854)"}, {"subsystem": "Glycerolipid metabolism (indirect)", "name": "Glycerone phosphate phosphohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01010", "ec-code": ["3.1.3.1", "3.1.3.2"], "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "dhap_c": -1.0, "pi_c": 1.0, "dha_c": 1.0}, "id": "RC01010", "gene_reaction_rule": "WBGene00013646 or ((WBGene00009146 or WBGene00014076 or WBGene00007328 or WBGene00007331) or (WBGene00020471 or WBGene00015161 or WBGene00011262) or WBGene00022379 or WBGene00008531) or (WBGene00206373 or WBGene00008802 or WBGene00008801 or WBGene00022246 or WBGene00004020 or WBGene00016152 or WBGene00004023 or WBGene00018696 or WBGene00011879 or WBGene00022181)"}, {"subsystem": "Glycerolipid metabolism", "name": "ATP:glycerone phosphotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01011", "ec-code": "2.7.1.29", "sbo": "SBO:0000176"}, "metabolites": {"h_c": 1.0, "dhap_c": 1.0, "dha_c": -1.0, "atp_c": -1.0, "adp_c": 1.0}, "id": "RC01011", "gene_reaction_rule": "WBGene00020962"}, {"subsystem": "Glycerophospholipid metabolism", "name": "Acyl-CoA:glycerone-phosphate O-acyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01013", "ec-code": "2.3.1.42", "sbo": "SBO:0000176"}, "metabolites": {"Rtotalcoa_c": -1.0, "dhap_c": -1.0, "coa_c": 1.0, "adhap_c": 1.0}, "id": "RC01013", "gene_reaction_rule": "WBGene00012911"}, {"subsystem": "Glycolysis / Gluconeogenesis", "name": "D-glyceraldehyde-3-phosphate aldose-ketose-isomerase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01015", "ec-code": "5.3.1.1", "sbo": "SBO:0000176"}, "metabolites": {"dhap_c": 1.0, "g3p_c": -1.0}, "id": "RC01015", "gene_reaction_rule": "WBGene00006601"}, {"subsystem": "Pyruvate metabolism", "name": "methylglyoxal synthase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01016", "ec-code": "4.2.3.3", "sbo": "SBO:0000176"}, "metabolites": {"dhap_c": -1.0, "pi_c": 1.0, "mthgxl_c": 1.0}, "id": "RC01016", "gene_reaction_rule": ""}, {"subsystem": "N-Glycan biosynthesis", "name": "Dolichol kinase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01018", "ec-code": "2.7.1.108", "sbo": "SBO:0000176"}, "metabolites": {"ctp_c": -1.0, "cdp_c": 1.0, "dolp_c": 1.0, "h_c": 1.0, "dolichol_c": -1.0}, "id": "RC01018", "gene_reaction_rule": "WBGene00044233"}, {"subsystem": "Lysine degradation", "name": "L-2-Aminoadipate-6-semialdehyde:NAD+ 6-oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03102", "ec-code": "1.2.1.31", "sbo": "SBO:0000176"}, "metabolites": {"h2o_m": -1.0, "L2aadp6sa_m": -1.0, "nadh_m": 1.0, "nad_m": -1.0, "h_m": 2.0, "L2aadp_m": 1.0}, "id": "RM03102", "gene_reaction_rule": "WBGene00000115"}, {"subsystem": "Lysine degradation", "name": "L-2-Aminoadipate-6-semialdehyde:NADP+ 6-oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03103", "ec-code": "1.2.1.31", "sbo": "SBO:0000176"}, "metabolites": {"nadph_m": 1.0, "h2o_m": -1.0, "nadp_m": -1.0, "L2aadp6sa_m": -1.0, "h_m": 2.0, "L2aadp_m": 1.0}, "id": "RM03103", "gene_reaction_rule": "WBGene00000115"}, {"subsystem": "Glycerophospholipid metabolism", "name": "K13510   lysophosphatidylcholine acyltransferase / lyso-PAF acetyltransferase [EC:2.3.1.23 2.3.1.67]; K13512   lysophospholipid acyltransferase [EC:2.3.1.23 2.3.1.-]; K13513   lysocardiolipin and lysophospholipid acyltransferase [EC:2.3.1.- 2.3.1.51]; K13514   lysophosphatidylglycerol acyltransferase 1 [EC:2.3.1.-]; K13519   lysophospholipid acyltransferase [EC:2.3.1.51 2.3.1.23 2.3.1.-]", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R09036", "ec-code": "2.3.1.-", "sbo": "SBO:0000176"}, "metabolites": {"pglyc_c": 1.0, "Rtotal2coa_c": -1.0, "coa_c": 1.0, "lpglyc_c": -1.0}, "id": "RC09036", "gene_reaction_rule": "WBGene00020264 or WBGene00022646 or WBGene00044631 or WBGene00019465 or WBGene00008581"}, {"subsystem": "Glycerophospholipid metabolism", "name": "acyl-CoA:1-acyl-sn-glycero-3-phosphoserine O-acyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R09035", "ec-code": "2.3.1.-", "sbo": "SBO:0000176"}, "metabolites": {"coa_c": 1.0, "Rtotal2coa_c": -1.0, "acg3ps_c": -1.0, "ps_c": 1.0}, "id": "RC09035", "gene_reaction_rule": "WBGene00020115 or WBGene00016934 or WBGene00007446"}, {"subsystem": "Exchange with the environment", "name": "D-Aspartate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"asp-D_e": -1.0}, "id": "EX00402", "gene_reaction_rule": ""}, {"subsystem": "Starch and sucrose metabolism", "name": "alpha,alpha-trehalose glucohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00010", "ec-code": "3.2.1.28", "sbo": "SBO:0000176"}, "metabolites": {"tre_c": -1.0, "h2o_c": -1.0, "glc-D_c": 2.0}, "id": "RC00010", "gene_reaction_rule": "WBGene00006607 or WBGene00006608 or WBGene00006609 or WBGene00006610 or WBGene00006611"}, {"subsystem": "Histone modification", "name": "S-adenosyl-L-methionine:histone-L-lysine N6-methyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03875", "ec-code": "2.1.1.43", "sbo": "SBO:0000176"}, "metabolites": {"amet_c": -1.0, "Nmelys_c": 1.0, "ahcys_c": 1.0, "h_c": 1.0, "Nlys_c": -1.0}, "id": "RC03875", "gene_reaction_rule": "(WBGene00011729 or WBGene00003040 or (WBGene00016603 or WBGene00019584) or WBGene00004782 or WBGene00019883 or WBGene00018023 or WBGene00003220 or WBGene00021515 or (WBGene00021474 or WBGene00010067 or WBGene00012302 or WBGene00010120 or WBGene00022512) or WBGene00016313 or WBGene00004781) or (WBGene00019690 or WBGene00020006 or WBGene00021282 or WBGene00008062 or WBGene00022431 or WBGene00008206)"}, {"subsystem": "Propanoate metabolism", "name": "Acyl-CoA hydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00383", "ec-code": "3.1.2.18", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "coa_c": 1.0, "ppa_c": 1.0, "ppcoa_c": -1.0, "h_c": 1.0}, "id": "RC00383", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Cytidine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"cytd_c": 1.0, "cytd_e": -1.0}, "id": "TCE0784", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Acetaldehyde transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"acald_c": 1.0, "acald_e": -1.0}, "id": "TCE1302", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "27-Hydroxycholesterol exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"xol27oh_e": -1.0}, "id": "EX15610", "gene_reaction_rule": ""}, {"subsystem": "Reactive oxygen species degradation", "name": "superoxide:superoxide oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00275", "ec-code": "1.15.1.1", "sbo": "SBO:0000176"}, "metabolites": {"o2_m": 1.0, "h_m": -2.0, "h2o2_m": 1.0, "o2s_m": -2.0}, "id": "RM00275", "gene_reaction_rule": "WBGene00004930 or WBGene00004931 or WBGene00004932"}, {"subsystem": "Exchange with the environment", "name": "Spermidine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"spmd_e": -1.0}, "id": "EX00315", "gene_reaction_rule": ""}, {"subsystem": "Cysteine and methionine metabolism", "name": "S-Adenosyl-L-methionine:L-homocysteine S-methyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00650", "ec-code": "2.1.1.10", "sbo": "SBO:0000176"}, "metabolites": {"amet_c": -1.0, "ahcys_c": 1.0, "met-L_c": 1.0, "h_c": 1.0, "hcys-L_c": -1.0}, "id": "RC00650", "gene_reaction_rule": "WBGene00020491"}, {"subsystem": "Fatty acid metabolism", "name": "long-chain-aldehyde dehydrogenase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01704", "ec-code": "1.2.1.48", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "nadh_c": 1.0, "m15hxdcal_c": -1.0, "h_c": 2.0, "nad_c": -1.0, "fa17p0iso_c": 1.0}, "id": "RC01704", "gene_reaction_rule": "WBGene00000110"}, {"subsystem": "Glycolysis / Gluconeogenesis", "name": "2-phospho-D-glycerate hydro-lyase (phosphoenolpyruvate-forming)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00658", "ec-code": "4.2.1.11", "sbo": "SBO:0000176"}, "metabolites": {"pep_c": 1.0, "h2o_c": 1.0, "2pg_c": -1.0}, "id": "RC00658", "gene_reaction_rule": "WBGene00011884"}, {"subsystem": "Glutathione metabolism", "name": "gamma-L-glutamyl-L-cysteine:glycine ligase (ADP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00497", "ec-code": "6.3.2.3", "sbo": "SBO:0000176"}, "metabolites": {"pi_c": 1.0, "atp_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "glucys_c": -1.0, "gthrd_c": 1.0, "gly_c": -1.0}, "id": "RC00497", "gene_reaction_rule": "WBGene00010941"}, {"subsystem": "Glutathione metabolism", "name": "glutathione gamma-glutamylaminopeptidase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00494", "ec-code": "3.4.19.13", "sbo": "SBO:0000176"}, "metabolites": {"glu-L_c": 1.0, "h2o_c": -1.0, "gthrd_c": -1.0, "cgly_c": 1.0}, "id": "RC00494", "gene_reaction_rule": "WBGene00016906 or WBGene00019204 or WBGene00011393 or WBGene00020590 or WBGene00012416 or WBGene00022397"}, {"subsystem": "Riboflavin metabolism", "name": "FAD diphosphatase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00160", "ec-code": "3.6.1.9", "sbo": "SBO:0000176"}, "metabolites": {"fad_e": -1.0, "fmn_e": 1.0, "amp_e": 1.0, "h2o_e": -1.0, "h_e": 2.0}, "id": "RE00160", "gene_reaction_rule": "WBGene00007753 or WBGene00007755"}, {"subsystem": "Arginine and Proline metabolism", "name": "D-4-Hydroxy-2-oxoglutarate glyoxylate-lyase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00471", "ec-code": "4.1.3.16", "sbo": "SBO:0000176"}, "metabolites": {"4h2oglt_m": -1.0, "glx_m": 1.0, "pyr_m": 1.0}, "id": "RM00471", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Tetrahydrobiopterin exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"thbpt_e": -1.0}, "id": "EX00272", "gene_reaction_rule": ""}, {"subsystem": "Glyoxylate and dicarboxylate metabolism", "name": "isocitrate lyase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00479", "ec-code": "4.1.3.1", "sbo": "SBO:0000176"}, "metabolites": {"glx_m": 1.0, "succ_m": 1.0, "icit_m": -1.0}, "id": "RM00479", "gene_reaction_rule": "WBGene00001564"}, {"subsystem": "Pentose phosphate pathway", "name": "beta-D-Fructose 6-phosphate:D-glyceraldehyde-3-phosphate glycolaldehyde transferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01830", "ec-code": "2.2.1.1", "sbo": "SBO:0000176"}, "metabolites": {"e4p_c": 1.0, "xu5p-D_c": 1.0, "g3p_c": -1.0, "f6p_c": -1.0}, "id": "RC01830", "gene_reaction_rule": "WBGene00008506"}, {"subsystem": "Starch and sucrose metabolism", "name": "UDP-D-glucuronate carboxy-lyase (UDP-D-xylose-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01384", "ec-code": "4.1.1.35", "sbo": "SBO:0000176"}, "metabolites": {"udpxyl_c": 1.0, "co2_c": 1.0, "h_c": -1.0, "udpglcur_c": -1.0}, "id": "RC01384", "gene_reaction_rule": "WBGene00005019"}, {"subsystem": "Exchange with the environment", "name": "L-Valine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"val-L_e": -1.0}, "id": "EX00183", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "D-Xylose exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"xyl-D_e": -1.0}, "id": "EX00181", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Cholesterol exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"chsterol_e": -1.0}, "id": "EX00187", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "L-Lactate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"lac-L_e": -1.0}, "id": "EX00186", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Cellobiose exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"clb_e": -1.0}, "id": "EX00185", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Ethanolamine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"etha_e": -1.0}, "id": "EX00189", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "L-Threonine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"thr-L_e": -1.0}, "id": "EX00188", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Retinol exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"retinol_e": -1.0}, "id": "EX00473", "gene_reaction_rule": ""}, {"subsystem": "Purine metabolism", "name": "Inosine 5-triphosphate pyrophosphohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00720", "ec-code": "3.6.1.19", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "ppi_c": 1.0, "h_c": 1.0, "itp_c": -1.0, "imp_c": 1.0}, "id": "RC00720", "gene_reaction_rule": "WBGene00001823"}, {"subsystem": "Purine metabolism", "name": "ATP:IDP phosphotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00722", "ec-code": "2.7.4.6", "sbo": "SBO:0000176"}, "metabolites": {"itp_c": 1.0, "idp_c": -1.0, "atp_c": -1.0, "adp_c": 1.0}, "id": "RC00722", "gene_reaction_rule": "WBGene00019899 or WBGene00021692 or WBGene00009119"}, {"subsystem": "Exchange with the environment", "name": "Cytidine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"cytd_e": -1.0}, "id": "EX00475", "gene_reaction_rule": ""}, {"subsystem": "Collagen biosynthesis", "name": "Procollagen registration", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "5.3.4.1", "sbo": "SBO:0000176"}, "metabolites": {"pcollg_diS_c": 1.0, "pcollg_mod_c": -1.0}, "id": "RCC0172", "gene_reaction_rule": "WBGene00003962 or WBGene00003963 or WBGene00003964 or WBGene00015168 or WBGene00015752 or WBGene00014807 or WBGene00013030 or WBGene00022836"}, {"subsystem": "Sphingolipid metabolism", "name": "beta-D-Galactosyl-1,4-beta-D-glucosylceramide galactohydrolase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R06099", "ec-code": "3.2.1.23", "sbo": "SBO:0000176"}, "metabolites": {"gluside_ce_c": 1.0, "h2o_c": -1.0, "galgluside_ce_c": -1.0, "gal_c": 1.0}, "id": "RC06099", "gene_reaction_rule": "WBGene00011832 or WBGene00019225"}, {"subsystem": "Miscellaneous", "name": "diphosphate phosphohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00004", "ec-code": "3.6.1.1", "sbo": "SBO:0000176"}, "metabolites": {"h2o_m": -1.0, "h_m": 1.0, "ppi_m": -1.0, "pi_m": 2.0}, "id": "RM00004", "gene_reaction_rule": "WBGene00008149"}, {"subsystem": "Ascorbate and aldarate metabolism", "name": "D-Glucuronolactone:NAD+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R02957", "ec-code": "1.2.1.3", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -2.0, "glcr_c": 1.0, "h_c": 3.0, "nad_c": -1.0, "nadh_c": 1.0, "glac_c": -1.0}, "id": "RC02957", "gene_reaction_rule": "(WBGene00000108 or WBGene00000110) or (WBGene00000117 or WBGene00000118)"}, {"subsystem": "Exchange with the environment", "name": "Chloride exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"cl_e": -1.0}, "id": "EX00698", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Prostaglandin D2 exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"prostgd2_e": -1.0}, "id": "EX00696", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Cholate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"cholate_e": -1.0}, "id": "EX00695", "gene_reaction_rule": ""}, {"subsystem": "Pentose phosphate pathway", "name": "6-phospho-D-gluconate:NADP+ 2-oxidoreductase (decarboxylating)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01528", "ec-code": "1.1.1.44", "sbo": "SBO:0000176"}, "metabolites": {"6pgc_c": -1.0, "nadph_c": 1.0, "nadp_c": -1.0, "co2_c": 1.0, "ru5p-D_c": 1.0}, "id": "RC01528", "gene_reaction_rule": "WBGene00012015"}, {"subsystem": "Pentose phosphate pathway", "name": "D-Ribulose-5-phosphate 3-epimerase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01529", "ec-code": "5.1.3.1", "sbo": "SBO:0000176"}, "metabolites": {"ru5p-D_c": -1.0, "xu5p-D_c": 1.0}, "id": "RC01529", "gene_reaction_rule": "WBGene00017272"}, {"subsystem": "Exchange with the environment", "name": "Reduced glutathione exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"gthrd_e": -1.0}, "id": "EX00051", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Hydrogen cyanide transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"cyan_m": 1.0, "cyan_c": -1.0}, "id": "TCM0059", "gene_reaction_rule": ""}, {"subsystem": "Cyanoamino acid metabolism", "name": "gamma-glutamyl-beta-cyanoalanine demand", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"gcynala_c": -1.0}, "id": "DMN0009", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "\"Adenosine 3',5'-bisphosphate\" exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"pap_e": -1.0}, "id": "EX00054", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Sulfate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"so4_e": -1.0}, "id": "EX00059", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Formate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"for_e": -1.0}, "id": "EX00058", "gene_reaction_rule": ""}, {"subsystem": "Primary bile acid biosynthesis", "name": "7alpha,26-dihydroxy-4-cholesten-3-one,NADPH:oxygen oxidoreductase (26-hydroxylating)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R08725", "ec-code": "1.14.13.15", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -2.0, "h2o_c": 3.0, "nadp_c": 2.0, "nadph_c": -2.0, "xol27one_c": -1.0, "h_c": -1.0, "7a3o4chlstnt_c": 1.0}, "id": "RC08725", "gene_reaction_rule": "WBGene00000905"}, {"subsystem": "Transport", "name": "dTDP and dUDP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dtdp_m": 1.0, "dudp_m": -1.0, "dtdp_c": -1.0, "dudp_c": 1.0}, "id": "TCM0208", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Nicotinamide transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"ncam_e": -1.0, "ncam_c": 1.0}, "id": "TCE0766", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "retinoyl glucuronide transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"retnglc_c": -1.0, "retnglc_e": 1.0}, "id": "TCE0437", "gene_reaction_rule": ""}, {"subsystem": "Ether lipid metabolism", "name": "CDPethanolamine:1-alkyl-2-acylglycerol ethanolaminephosphotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R06364", "ec-code": "2.7.8.1", "sbo": "SBO:0000176"}, "metabolites": {"cdpea_c": -1.0, "akac2gpe_c": 1.0, "cmp_c": 1.0, "h_c": 1.0, "akac2g_c": -1.0}, "id": "RC06364", "gene_reaction_rule": "WBGene00009057"}, {"subsystem": "Arginine and proline metabolism", "name": "L-glutamate-5-semialdehyde:NADP+ 5-oxidoreductase (phosphorylating)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03313", "ec-code": "1.2.1.41", "sbo": "SBO:0000176"}, "metabolites": {"nadph_m": -1.0, "nadp_m": 1.0, "glu5sa_m": 1.0, "glu5p_m": -1.0, "pi_m": 1.0, "h_m": -1.0}, "id": "RM03313", "gene_reaction_rule": "WBGene00011938"}, {"subsystem": "Exchange with the environment", "name": "Fe2+ exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"fe2_e": -1.0}, "id": "EX14818", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Fe3+ exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"fe3_e": -1.0}, "id": "EX14819", "gene_reaction_rule": ""}, {"subsystem": "Selenocompound metabolism", "name": "ATP:selenate adenylyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R04929", "ec-code": "2.7.7.4", "sbo": "SBO:0000176"}, "metabolites": {"adsel_c": 1.0, "ppi_c": 1.0, "sel_c": -1.0, "h_c": -1.0, "atp_c": -1.0}, "id": "RC04929", "gene_reaction_rule": "WBGene00004091"}, {"subsystem": "Selenocompound metabolism (indirect)", "name": "ATP:adenylylsulfate 3'-phosphotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R04928", "ec-code": "2.7.1.25", "sbo": "SBO:0000176"}, "metabolites": {"adsel_c": -1.0, "3padsel_c": 1.0, "adp_c": 1.0, "atp_c": -1.0, "h_c": 1.0}, "id": "RC04928", "gene_reaction_rule": "WBGene00004091"}, {"subsystem": "Transport", "name": "(R)-Pantothenate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"pnto-R_c": 1.0, "pnto-R_e": -1.0}, "id": "TCE1169", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "L-Glutamate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"glu-L_c": 1.0, "glu-L_e": -1.0}, "id": "TCE1164", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "L-Malate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"mal-L_c": 1.0, "mal-L_e": -1.0}, "id": "TCE1161", "gene_reaction_rule": ""}, {"subsystem": "Carnitine shuttle", "name": "Acetyl-CoA:carnitine O-acetyltransferase I", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02396", "ec-code": "2.3.1.7", "sbo": "SBO:0000176"}, "metabolites": {"crn_c": -1.0, "acrn_c": 1.0, "coa_c": 1.0, "accoa_c": -1.0}, "id": "RC02396", "gene_reaction_rule": "WBGene00007175"}, {"subsystem": "Carnitine biosynthesis", "name": "4-Trimethylammoniobutanoate,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02397", "ec-code": "1.14.11.1", "sbo": "SBO:0000176"}, "metabolites": {"akg_c": -1.0, "o2_c": -1.0, "co2_c": 1.0, "succ_c": 1.0, "4tmeabutn_c": -1.0, "crn_c": 1.0}, "id": "RC02397", "gene_reaction_rule": "WBGene00001522"}, {"subsystem": "Methane metabolism", "name": "S-(hydroxymethyl)glutathione:NADP+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R07140", "ec-code": "1.1.1.284", "sbo": "SBO:0000176"}, "metabolites": {"h_c": 1.0, "nadp_c": -1.0, "nadph_c": 1.0, "hmgth_c": -1.0, "Sfglutth_c": 1.0}, "id": "RC07140", "gene_reaction_rule": "WBGene00019240"}, {"subsystem": "Transport", "name": "Sphingomyelin uptake", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"h2o_c": -1.0, "atp_c": -1.0, "sphmyln_ce_e": -1.0, "sphmyln_ce_c": 1.0, "h_c": 1.0, "adp_c": 1.0, "pi_c": 1.0}, "id": "TCE5401", "gene_reaction_rule": ""}, {"subsystem": "Fructose and mannose metabolism", "name": "D-Fructose-2,6-bisphosphate 2-phosphohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02731", "ec-code": "3.1.3.46", "sbo": "SBO:0000176"}, "metabolites": {"f26bp_c": -1.0, "h2o_c": -1.0, "pi_c": 1.0, "f6p_c": 1.0}, "id": "RC02731", "gene_reaction_rule": "WBGene00022456 or WBGene00019295"}, {"subsystem": "Fructose and mannose metabolism", "name": "ATP:D-fructose-6-phosphate 2-phosphotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02732", "ec-code": "2.7.1.105", "sbo": "SBO:0000176"}, "metabolites": {"h_c": 1.0, "f26bp_c": 1.0, "adp_c": 1.0, "atp_c": -1.0, "f6p_c": -1.0}, "id": "RC02732", "gene_reaction_rule": "WBGene00019295 or WBGene00022456"}, {"subsystem": "Pentose phosphate pathway", "name": "beta-D-Glucose-6-phosphate:NADP+ 1-oxoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R02736", "ec-code": "1.1.1.49", "sbo": "SBO:0000176"}, "metabolites": {"g6p-B_c": -1.0, "nadp_c": -1.0, "nadph_c": 1.0, "6pgl_c": 1.0, "h_c": 1.0}, "id": "RC02736", "gene_reaction_rule": "WBGene00007108"}, {"subsystem": "Starch and sucrose metabolism", "name": "trehalose 6-phosphate synthase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02737", "ec-code": "2.4.1.15", "sbo": "SBO:0000176"}, "metabolites": {"tre6p_c": 1.0, "udp_c": 1.0, "udpg_c": -1.0, "h_c": 1.0, "g6p-A_c": -1.0}, "id": "RC02737", "gene_reaction_rule": "WBGene00006602 or WBGene00006603"}, {"subsystem": "Glycolysis / Gluconeogenesis", "name": "alpha-D-Glucose 6-phosphate ketol-isomerase (producing beta-D-Glucose 6-phosphate)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R02739", "ec-code": "5.3.1.9", "sbo": "SBO:0000176"}, "metabolites": {"g6p-B_c": 1.0, "g6p-A_c": -1.0}, "id": "RC02739", "gene_reaction_rule": "WBGene00013597"}, {"subsystem": "Pentose and glucuronate interconversions", "name": "L-Gulonate:NAD+ 3-oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R02640", "ec-code": "1.1.1.45", "sbo": "SBO:0000176"}, "metabolites": {"nadh_c": 1.0, "3dhguln_c": 1.0, "nad_c": -1.0, "guln_c": -1.0, "h_c": 1.0}, "id": "RC02640", "gene_reaction_rule": "((WBGene00022130))"}, {"subsystem": "Exchange with the environment", "name": "Leukotriene B4 exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"leuktrB4_e": -1.0}, "id": "EX02165", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "L-Leucine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"leu-L_c": 1.0, "leu-L_e": -1.0}, "id": "TCE0531", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "L-Carnitine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"crn_e": -1.0}, "id": "EX00318", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "4-Aminobutanoate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"4abut_m": 1.0, "4abut_c": -1.0}, "id": "TCM1286", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "myo-Inositol transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"inost_e": -1.0, "inost_c": 1.0}, "id": "TCE0389", "gene_reaction_rule": ""}, {"subsystem": "Sulfur metabolism", "name": "Sulfite:oxygen oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00533", "ec-code": "1.8.3.1", "sbo": "SBO:0000176"}, "metabolites": {"so4_c": 1.0, "so3_c": -1.0, "h2o2_m": 1.0, "h2o_c": -1.0, "o2_m": -1.0}, "id": "RM00533", "gene_reaction_rule": "WBGene00010397"}, {"subsystem": "Transport", "name": "Cholesterol transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"h2o_c": -1.0, "chsterol_c": -1.0, "atp_c": -1.0, "chsterol_e": 1.0, "h_c": 1.0, "adp_c": 1.0, "pi_c": 1.0}, "id": "TCE0384", "gene_reaction_rule": ""}, {"subsystem": "Inositol phosphate metabolism", "name": "ATP:1-phosphatidyl-1D-myo-inositol-4-phosphate 5-phosphotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03469", "ec-code": "2.7.1.68", "sbo": "SBO:0000176"}, "metabolites": {"pail45p_c": 1.0, "pail4p_c": -1.0, "adp_c": 1.0, "atp_c": -1.0, "h_c": 1.0}, "id": "RC03469", "gene_reaction_rule": "WBGene00004087"}, {"subsystem": "Transport", "name": "L-Isoleucine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"ile-L_e": -1.0, "ile-L_c": 1.0}, "id": "TCE0382", "gene_reaction_rule": ""}, {"subsystem": "Fatty acid elongation", "name": "trans-Dec-2-enoyl-CoA reductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R04753", "ec-code": "1.3.1.38", "sbo": "SBO:0000176"}, "metabolites": {"dc2coa_m": -1.0, "h_m": -1.0, "dcacoa_m": 1.0, "nadph_m": -1.0, "nadp_m": 1.0}, "id": "RM04753", "gene_reaction_rule": "WBGene00012375 or WBGene00012970"}, {"subsystem": "Fatty acid elongation", "name": "(S)-3-hydroxydodecanoyl-CoA:NAD+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R04741", "ec-code": ["1.1.1.211", "1.1.1.35"], "sbo": "SBO:0000176"}, "metabolites": {"nad_m": 1.0, "h_m": -1.0, "3oddcoa_m": -1.0, "nadh_m": -1.0, "3hddcoa_m": 1.0}, "id": "RM04741", "gene_reaction_rule": "(WBGene00007129 or WBGene00010035 or WBGene00001157 or WBGene00001158 or WBGene00019978) or (WBGene00020347 or WBGene00001150)"}, {"subsystem": "Fatty acid elongation", "name": "(S)-3-Hydroxytetradecanoyl-CoA hydro-lyase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R04740", "ec-code": "4.2.1.17", "sbo": "SBO:0000176"}, "metabolites": {"td2coa_m": 1.0, "h2o_m": 1.0, "3htdcoa_m": -1.0}, "id": "RM04740", "gene_reaction_rule": "(WBGene00001155 or WBGene00001156) or (WBGene00020347 or WBGene00001150) or WBGene00001152"}, {"subsystem": "Fatty acid elongation", "name": "(S)-hydroxydecanoyl-CoA:NAD+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R04743", "ec-code": ["1.1.1.211", "1.1.1.35"], "sbo": "SBO:0000176"}, "metabolites": {"nad_m": 1.0, "3hdcoa_m": 1.0, "h_m": -1.0, "3odcoa_m": -1.0, "nadh_m": -1.0}, "id": "RM04743", "gene_reaction_rule": "(WBGene00007129 or WBGene00010035 or WBGene00001157 or WBGene00001158 or WBGene00019978) or (WBGene00020347 or WBGene00001150)"}, {"subsystem": "Ether lipid metabolism", "name": "alkyl acylglycerol phosphocholine transferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R07389", "ec-code": "2.7.8.2", "sbo": "SBO:0000176"}, "metabolites": {"cmp_c": 1.0, "akac2gchol_c": 1.0, "cdpchol_c": -1.0, "h_c": 1.0, "akac2g_c": -1.0}, "id": "RC07389", "gene_reaction_rule": "WBGene00013024"}, {"subsystem": "Fatty acid elongation", "name": "(S)-hydroxyoctanoyl-CoA:NAD+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R04745", "ec-code": ["1.1.1.211", "1.1.1.35"], "sbo": "SBO:0000176"}, "metabolites": {"3oocoa_m": -1.0, "nad_m": 1.0, "h_m": -1.0, "nadh_m": -1.0, "3hocoa_m": 1.0}, "id": "RM04745", "gene_reaction_rule": "(WBGene00007129 or WBGene00010035 or WBGene00001157 or WBGene00001158 or WBGene00019978) or (WBGene00020347 or WBGene00001150)"}, {"subsystem": "Fatty acid elongation", "name": "(S)-Hydroxydecanoyl-CoA hydro-lyase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R04744", "ec-code": "4.2.1.17", "sbo": "SBO:0000176"}, "metabolites": {"3hdcoa_m": -1.0, "h2o_m": 1.0, "dc2coa_m": 1.0}, "id": "RM04744", "gene_reaction_rule": "(WBGene00001155 or WBGene00001156) or (WBGene00020347 or WBGene00001150) or WBGene00001152"}, {"subsystem": "Fatty acid elongation", "name": "Hexanoyl-CoA:acetyl-CoA C-acyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R04747", "ec-code": "2.3.1.16", "sbo": "SBO:0000176"}, "metabolites": {"3oocoa_m": -1.0, "accoa_m": 1.0, "coa_m": -1.0, "hxcoa_m": 1.0}, "id": "RM04747", "gene_reaction_rule": "WBGene00015125 or WBGene00009952"}, {"subsystem": "Fatty acid elongation", "name": "(S)-Hydroxyoctanoyl-CoA hydro-lyase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R04746", "ec-code": "4.2.1.17", "sbo": "SBO:0000176"}, "metabolites": {"3hocoa_m": -1.0, "h2o_m": 1.0, "oc2coa_m": 1.0}, "id": "RM04746", "gene_reaction_rule": "(WBGene00001155 or WBGene00001156) or (WBGene00020347 or WBGene00001150) or WBGene00001152"}, {"subsystem": "Fatty acid elongation", "name": "(S)-Hydroxyhexanoyl-CoA hydro-lyase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R04749", "ec-code": "4.2.1.17", "sbo": "SBO:0000176"}, "metabolites": {"hx2coa_m": 1.0, "h2o_m": 1.0, "3hhcoa_m": -1.0}, "id": "RM04749", "gene_reaction_rule": "(WBGene00001155 or WBGene00001156) or (WBGene00020347 or WBGene00001150) or WBGene00001152"}, {"subsystem": "Fatty acid elongation", "name": "(S)-hydroxyhexanoyl-CoA:NAD+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R04748", "ec-code": ["1.1.1.211", "1.1.1.35"], "sbo": "SBO:0000176"}, "metabolites": {"nad_m": 1.0, "3ohcoa_m": -1.0, "h_m": -1.0, "nadh_m": -1.0, "3hhcoa_m": 1.0}, "id": "RM04748", "gene_reaction_rule": "(WBGene00007129 or WBGene00010035 or WBGene00001157 or WBGene00001158 or WBGene00019978) or (WBGene00020347 or WBGene00001150)"}, {"subsystem": "Ether lipid metabolism", "name": "Lysoplasmalogen ethanolamine phosphohydrolase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R07380", "ec-code": "3.1.4.-", "sbo": "SBO:0000176"}, "metabolites": {"h_c": 1.0, "alken2gpe_c": -1.0, "alkenglyc_c": 1.0, "h2o_c": -1.0, "ethamp_c": 1.0}, "id": "RC07380", "gene_reaction_rule": "WBGene00020195 or WBGene00007753 or WBGene00007755 or WBGene00008776"}, {"subsystem": "Transport", "name": "L-Tryptophan transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"trp-L_e": -1.0, "trp-L_c": 1.0}, "id": "TCE0542", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "propanediol transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"12ppd-R_c": 1.0, "12ppd-R_e": -1.0}, "id": "TCE5063", "gene_reaction_rule": ""}, {"subsystem": "Ether lipid metabolism", "name": "O-1-Alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + CMP <=> 1-Alkenyl-2-acylglycerol + CDP-ethanolamine", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R07384", "ec-code": "2.7.8.1", "sbo": "SBO:0000176"}, "metabolites": {"cdpea_c": 1.0, "alkenac2g_c": 1.0, "alkenac2gpe_c": -1.0, "h_c": -1.0, "cmp_c": -1.0}, "id": "RC07384", "gene_reaction_rule": "WBGene00009057 or WBGene00018797"}, {"subsystem": "Ether lipid metabolism", "name": "O-1-Alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine phosphatidohydrolase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R07385", "ec-code": "3.1.4.4", "sbo": "SBO:0000176"}, "metabolites": {"alkenac2gp_c": 1.0, "h2o_c": -1.0, "alkenac2gpe_c": -1.0, "h_c": 1.0, "etha_c": 1.0}, "id": "RC07385", "gene_reaction_rule": "WBGene00004040 or (WBGene00017316 or WBGene00020256 or WBGene00013080)"}, {"subsystem": "Pyruvate metabolism", "name": "(R)-S-Lactoylglutathione hydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01736", "ec-code": "3.1.2.6", "sbo": "SBO:0000176"}, "metabolites": {"lac-D_m": 1.0, "lgt-S_m": -1.0, "h_m": 1.0, "h2o_m": -1.0, "gthrd_m": 1.0}, "id": "RM01736", "gene_reaction_rule": "WBGene00012459"}, {"subsystem": "Ascorbate and aldarate metabolism", "name": "myo-Inositol:oxygen oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01184", "ec-code": "1.13.99.1", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "h2o_c": 1.0, "inost_c": -1.0, "h_c": 1.0, "glcur_c": 1.0}, "id": "RC01184", "gene_reaction_rule": "WBGene00016920"}, {"subsystem": "Exchange with the environment", "name": "enol-Phenylpyruvate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"enphpyr_e": -1.0}, "id": "EX02763", "gene_reaction_rule": ""}, {"subsystem": "Cysteine and methionine metabolism", "name": "O3-Acetyl-L-serine acetate-lyase (adding hydrogen sulfide)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R03601", "ec-code": "2.5.1.47", "sbo": "SBO:0000176"}, "metabolites": {"selcys_c": 1.0, "seln_c": -1.0, "acser_c": -1.0, "ac_c": 1.0}, "id": "RC03601", "gene_reaction_rule": "WBGene00008490 or WBGene00008732 or WBGene00019094 or WBGene00020797 or WBGene00007653 or WBGene00010759 or WBGene00019962 or WBGene00019096"}, {"subsystem": "Inositol phosphate metabolism", "name": "1D-myo-Inositol 1-phosphate phosphohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01185", "ec-code": "3.1.3.25", "sbo": "SBO:0000176"}, "metabolites": {"inost_c": 1.0, "h2o_c": -1.0, "pi_c": 1.0, "mi1p-D_c": -1.0}, "id": "RC01185", "gene_reaction_rule": "(WBGene00008765 or WBGene00012390)"}, {"subsystem": "Primary bile acid biosynthesis", "name": "cholesterol 26-hydroxylase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R08505", "ec-code": "1.14.13.15", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "h2o_c": 1.0, "nadp_c": 1.0, "nadph_c": -1.0, "h_c": -1.0, "xol27oh_c": 1.0, "chsterol_c": -1.0}, "id": "RC08505", "gene_reaction_rule": "WBGene00000905"}, {"subsystem": "Purine metabolism", "name": "5-Phospho-D-ribosylamine:glycine ligase (ADP-forming)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R04144", "ec-code": "6.3.4.13", "sbo": "SBO:0000176"}, "metabolites": {"pram_c": -1.0, "atp_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "gar_c": 1.0, "pi_c": 1.0, "gly_c": -1.0}, "id": "RC04144", "gene_reaction_rule": "WBGene00018174"}, {"subsystem": "Fructose and mannose metabolism", "name": "ATP:D-fructose 6-phosphotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00867", "ec-code": "2.7.1.1", "sbo": "SBO:0000176"}, "metabolites": {"h_c": 1.0, "f6p_c": 1.0, "fru_c": -1.0, "atp_c": -1.0, "adp_c": 1.0}, "id": "RC00867", "gene_reaction_rule": "WBGene00008780 or WBGene00010416 or WBGene00022306"}, {"subsystem": "Riboflavin metabolism", "name": "FAD diphosphatase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00160", "ec-code": "3.6.1.9", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "fmn_c": 1.0, "amp_c": 1.0, "fad_c": -1.0, "h_c": 2.0}, "id": "RC00160", "gene_reaction_rule": "WBGene00007753 or WBGene00007755"}, {"subsystem": "Exchange with the environment", "name": "Dehydroascorbate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"dhdascb_e": -1.0}, "id": "EX05422", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "2-Oxobutanoate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"2obut_e": -1.0}, "id": "EX00109", "gene_reaction_rule": ""}, {"subsystem": "Phenylalanine metabolism", "name": "L-Phenylalanine:2-oxoglutarate aminotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00694", "ec-code": ["2.6.1.1", "2.6.1.5"], "sbo": "SBO:0000176"}, "metabolites": {"akg_c": -1.0, "glu-L_c": 1.0, "phpyr_c": 1.0, "phe-L_c": -1.0}, "id": "RC00694", "gene_reaction_rule": "WBGene00020146 or WBGene00009628"}, {"subsystem": "Exchange with the environment", "name": "Anthranilate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"anth_e": -1.0}, "id": "EX00108", "gene_reaction_rule": ""}, {"subsystem": "Pantothenate and CoA biosynthesis", "name": "N-[(R)-4-Phosphopantothenoyl]-L-cysteine carboxy-lyase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03269", "ec-code": "4.1.1.36", "sbo": "SBO:0000176"}, "metabolites": {"pan4p_c": 1.0, "co2_c": 1.0, "4ppcys_c": -1.0, "h_c": -1.0}, "id": "RC03269", "gene_reaction_rule": "WBGene00009138"}, {"subsystem": "Exchange with the environment", "name": "4-Methyl-2-oxopentanoate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"4mop_e": -1.0}, "id": "EX00233", "gene_reaction_rule": ""}, {"subsystem": "Inositol phosphate metabolism", "name": "ATP:1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate 3-phosphotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R04545", "ec-code": "2.7.1.153", "sbo": "SBO:0000176"}, "metabolites": {"h_c": 1.0, "pail345p_c": 1.0, "pail45p_c": -1.0, "atp_c": -1.0, "adp_c": 1.0}, "id": "RC04545", "gene_reaction_rule": "WBGene00000090 and WBGene00000001"}, {"subsystem": "Transport", "name": "Hydroxymethylglutaryl-CoA transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"hmgcoa_c": -1.0, "hmgcoa_m": 1.0}, "id": "TCM1289", "gene_reaction_rule": ""}, {"subsystem": "beta-Alanine metabolism", "name": "L-aspartate 1-carboxy-lyase (beta-alanine-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00489", "ec-code": "4.1.1.15", "sbo": "SBO:0000176"}, "metabolites": {"asp-L_m": -1.0, "h_m": -1.0, "co2_m": 1.0, "ala-B_m": 1.0}, "id": "RM00489", "gene_reaction_rule": "WBGene00006762"}, {"subsystem": "Cyanoamino acid metabolism", "name": "(5-Glutamyl)-peptide:amino-acid 5-glutamyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R03970", "ec-code": "2.3.2.2", "sbo": "SBO:0000176"}, "metabolites": {"cyanala_c": -1.0, "glu-L_c": -1.0, "h2o_c": 1.0, "h_c": -1.0, "gcynala_c": 1.0}, "id": "RC03970", "gene_reaction_rule": "WBGene00016906 or WBGene00019204 or WBGene00011393 or WBGene00020590 or WBGene00012416 or WBGene00022397"}, {"subsystem": "Carnitine biosynthesis", "name": "3-hydroxy-6-N-trimethyllysine aldolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03284", "ec-code": "4.1.2.-", "sbo": "SBO:0000176"}, "metabolites": {"4tmeabut_c": 1.0, "3htmelys_c": -1.0, "gly_c": 1.0}, "id": "RC03284", "gene_reaction_rule": ""}, {"subsystem": "Carnitine biosynthesis", "name": "4-Trimethylammoniobutanal:NAD+ 1-oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03283", "ec-code": ["1.2.1.3", "1.2.1.47"], "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "nadh_c": 1.0, "4tmeabut_c": -1.0, "h_c": 2.0, "nad_c": -1.0, "4tmeabutn_c": 1.0}, "id": "RC03283", "gene_reaction_rule": "(WBGene00000108 or WBGene00000110) or (WBGene00000117 or WBGene00000118)"}, {"subsystem": "Citrate cycle (TCA cycle)", "name": "Isocitrate:NADP+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00267", "ec-code": "1.1.1.42", "sbo": "SBO:0000176"}, "metabolites": {"akg_c": 1.0, "nadph_c": 1.0, "co2_c": 1.0, "icit_c": -1.0, "nadp_c": -1.0}, "id": "RC00267", "gene_reaction_rule": "WBGene00010317"}, {"subsystem": "Alanine, aspartate and glutamate metabolism", "name": "L-glutamate 1-carboxy-lyase (4-aminobutanoate-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00261", "ec-code": "4.1.1.15", "sbo": "SBO:0000176"}, "metabolites": {"glu-L_c": -1.0, "co2_c": 1.0, "h_c": -1.0, "4abut_c": 1.0}, "id": "RC00261", "gene_reaction_rule": "WBGene00006762"}, {"subsystem": "Exchange with the environment", "name": "Uracil exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"ura_e": -1.0}, "id": "EX00106", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "L-sulfolactate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"sl-L_m": 1.0, "sl-L_c": -1.0}, "id": "TCM5067", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Trimethyl lysine transport to mitochondria", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"tmlys_c": -1.0, "tmlys_m": 1.0}, "id": "TCM5064", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "3-hydroxy trimethyl lysine transport from mitochondria", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"3htmelys_c": -1.0, "3htmelys_m": 1.0}, "id": "TCM5065", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "D-3-Amino-isobutanoate transport (cytosol/mitochondria)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"3aib-D_m": 1.0, "3aib-D_c": -1.0}, "id": "TCM5062", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "methylglyoxal transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"mthgxl_m": 1.0, "mthgxl_c": -1.0}, "id": "TCM5060", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "iron transport (cytosol/mitochondria)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"fe3_c": -1.0, "fe3_m": 1.0}, "id": "TCM5061", "gene_reaction_rule": ""}, {"subsystem": "Valine, leucine and isoleucine degradation", "name": "(S)-2-methylbutanoyl-CoA:acceptor 2,3-oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R03172", "ec-code": ["1.3.99.12", "1.3.8.1"], "sbo": "SBO:0000176"}, "metabolites": {"etfrd_m": 1.0, "etfox_m": -1.0, "2mbcoa_m": -1.0, "2mb2coa_m": 1.0}, "id": "RM03172", "gene_reaction_rule": "WBGene00016943 or WBGene00015894 or WBGene00019433"}, {"subsystem": "Glycerophospholipid metabolism", "name": "Acetylcholine aectylhydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01026", "ec-code": "3.1.1.7", "sbo": "SBO:0000176"}, "metabolites": {"chol_c": 1.0, "h2o_c": -1.0, "ach_c": -1.0, "ac_c": 1.0, "h_c": 1.0}, "id": "RC01026", "gene_reaction_rule": "WBGene00000035 or WBGene00000036 or WBGene00000038"}, {"subsystem": "Glycerophospholipid metabolism", "name": "ATP:choline phosphotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01021", "ec-code": "2.7.1.32", "sbo": "SBO:0000176"}, "metabolites": {"chol_c": -1.0, "cholp_c": 1.0, "adp_c": 1.0, "atp_c": -1.0, "h_c": 1.0}, "id": "RC01021", "gene_reaction_rule": "(WBGene00000509 or WBGene00000510 or WBGene00000511 or WBGene00000512 or WBGene00000513) or WBGene00000514"}, {"subsystem": "Glycerophospholipid metabolism", "name": "Acetyl-CoA:choline O-acetyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01023", "ec-code": "2.3.1.6", "sbo": "SBO:0000176"}, "metabolites": {"chol_c": -1.0, "ach_c": 1.0, "coa_c": 1.0, "accoa_c": -1.0}, "id": "RC01023", "gene_reaction_rule": "WBGene00000481"}, {"subsystem": "Reactive oxygen species degradation", "name": "catalase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00009", "ec-code": "1.11.1.6", "sbo": "SBO:0000176"}, "metabolites": {"h2o2_c": -2.0, "h2o_c": 2.0, "o2_c": 1.0}, "id": "RC00009", "gene_reaction_rule": "WBGene00000830 or WBGene00000831 or WBGene00013220"}, {"subsystem": "Miscellaneous", "name": "diphosphate phosphohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00004", "ec-code": "3.6.1.1", "sbo": "SBO:0000176"}, "metabolites": {"ppi_c": -1.0, "pi_c": 2.0, "h2o_c": -1.0, "h_c": 1.0}, "id": "RC00004", "gene_reaction_rule": "WBGene00007548 or WBGene00008149"}, {"subsystem": "Fatty acid metabolism", "name": "Octanoyl-CoA:oxygen 2-oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R03777", "ec-code": ["1.3.8.7", "1.3.8.1"], "sbo": "SBO:0000176"}, "metabolites": {"occoa_m": -1.0, "etfox_m": -1.0, "etfrd_m": 1.0, "oc2coa_m": 1.0}, "id": "RM03777", "gene_reaction_rule": "(WBGene00020812 or WBGene00019406 or WBGene00020366) or (WBGene00016943 or WBGene00015894)"}, {"subsystem": "Fatty acid elongation", "name": "trans-Oct-2-enoyl-CoA reductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03776", "ec-code": "1.3.1.38", "sbo": "SBO:0000176"}, "metabolites": {"occoa_m": 1.0, "nadph_m": -1.0, "h_m": -1.0, "nadp_m": 1.0, "oc2coa_m": -1.0}, "id": "RM03776", "gene_reaction_rule": "WBGene00012375 or WBGene00012970"}, {"subsystem": "Fatty acid elongation", "name": "Octanoyl-CoA:acetyl-CoA C-acyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R03778", "ec-code": "2.3.1.16", "sbo": "SBO:0000176"}, "metabolites": {"accoa_m": 1.0, "coa_m": -1.0, "occoa_m": 1.0, "3odcoa_m": -1.0}, "id": "RM03778", "gene_reaction_rule": "WBGene00015125 or WBGene00009952"}, {"subsystem": "Protein modification", "name": "S-adenosyl-L-methionine:2-(3-carboxy-3-aminopropyl)-L-histidine-[translation elongation factor 2] methyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R10306", "ec-code": "2.1.1.98", "sbo": "SBO:0000176"}, "metabolites": {"amet_c": -3.0, "ahcys_c": 3.0, "h_c": 3.0, "caphis_c": -1.0, "pdipht_c": 1.0}, "id": "RC10306", "gene_reaction_rule": "WBGene00007194"}, {"subsystem": "Sphingolipid metabolism", "name": "Palmitoyl-CoA:L-serine C-palmitoyltransferase (decarboxylating)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01281", "ec-code": "2.3.1.50", "sbo": "SBO:0000176"}, "metabolites": {"ser-L_c": -1.0, "3dsphgn_ce_c": 1.0, "fa17p0isocoa_c": -1.0, "coa_c": 1.0, "h_c": -1.0, "co2_c": 1.0}, "id": "RC01281", "gene_reaction_rule": "WBGene00016020 or WBGene00018398 or WBGene00011932"}, {"subsystem": "Fatty acid metabolism", "name": "Palmitate:CoA ligase (AMP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01280", "ec-code": "6.2.1.3", "sbo": "SBO:0000176"}, "metabolites": {"atp_c": -1.0, "ppi_c": 1.0, "pmtcoa_c": 1.0, "coa_c": -1.0, "amp_c": 1.0, "hdca_c": -1.0}, "id": "RC01280", "gene_reaction_rule": "WBGene00009221 or WBGene00020343 or WBGene00018152 or WBGene00013575 or WBGene00022037 or WBGene00019920 or WBGene00016716 or WBGene00011173"}, {"subsystem": "Carnitine biosynthesis", "name": "Protein-lysine methylase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R03875", "R04866", "R04867"], "ec-code": "2.1.1.43", "sbo": "SBO:0000176"}, "metabolites": {"peptmelys_c": 1.0, "amet_c": -3.0, "peplys_c": -1.0, "h_c": 3.0, "ahcys_c": 3.0}, "id": "RCC0177", "gene_reaction_rule": "(WBGene00011729 or WBGene00003040 or (WBGene00016603 or WBGene00019584) or WBGene00004782 or WBGene00019883 or WBGene00018023 or WBGene00003220 or WBGene00021515 or (WBGene00021474 or WBGene00010067 or WBGene00012302 or WBGene00010120 or WBGene00022512) or WBGene00016313 or WBGene00004781) or (WBGene00019690 or WBGene00020006 or WBGene00021282 or WBGene00008062 or WBGene00022431 or WBGene00008206)"}, {"subsystem": "Collagen biosynthesis", "name": "Collagen formation", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"tropcollgtyrX_c": -0.00186, "tropcollg_rest_c": -0.99814, "collg_c": 1.0}, "id": "RCC0176", "gene_reaction_rule": ""}, {"subsystem": "Collagen biosynthesis", "name": "Tropocollagen crosslinking by dual oxidase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": ["1.6.3.1", "1.11.1.7"], "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "h2o_c": 2.0, "nadp_c": 1.0, "nadph_c": -1.0, "tropcollgtyr_c": -2.0, "tropcollgtyrX_c": 2.0, "h_c": -1.0}, "id": "RCC0175", "gene_reaction_rule": "WBGene00000253"}, {"subsystem": "Nicotinate and nicotinamide metabolism", "name": "ATP:nicotinamide-nucleotide adenylyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00137", "ec-code": ["2.7.7.1", "2.7.7.18"], "sbo": "SBO:0000176"}, "metabolites": {"ppi_c": 1.0, "nad_c": 1.0, "nmn_c": -1.0, "h_c": -1.0, "atp_c": -1.0}, "id": "RC00137", "gene_reaction_rule": "WBGene00012295 or WBGene00009176"}, {"subsystem": "Collagen biosynthesis", "name": "Procollagen trimerization", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"pcollg_tri_c": 1.0, "pcollg_diS_c": -3.0}, "id": "RCC0173", "gene_reaction_rule": ""}, {"subsystem": "Citrate cycle (TCA cycle)", "name": "Isocitrate:NADP+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00267", "ec-code": "1.1.1.42", "sbo": "SBO:0000176"}, "metabolites": {"co2_m": 1.0, "nadph_m": 1.0, "icit_m": -1.0, "akg_m": 1.0, "nadp_m": -1.0}, "id": "RM00267", "gene_reaction_rule": "WBGene00010317 or WBGene00007942"}, {"subsystem": "Collagen biosynthesis", "name": "Procollagen synthesis (modified protein)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"pcollg4hpro_c": -0.072079, "pcollg_rest_c": -0.921682, "pcollg_mod_c": 1.0, "pcollg5hlys_c": -0.006239}, "id": "RCC0171", "gene_reaction_rule": ""}, {"subsystem": "Collagen biosynthesis", "name": "Procollagen synthesis (unmodified protein)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"trnaphe_c": 0.017276, "h2o_c": -2.324, "mettrna_c": -0.017249, "trnagln_c": 0.046288, "tyrtrna_c": -0.022921, "trnahis_c": 0.014203, "histrna_c": -0.014203, "trnaglu_c": 0.049537, "trnaasp_c": 0.049284, "h_c": 3.324, "trnaval_c": 0.043435, "trnaile_c": 0.027694, "phetrna_c": -0.017276, "trptrna_c": -0.004785, "trnamet_c": 0.017249, "leutrna_c": -0.033232, "cystrna_c": -0.027047, "iletrna_c": -0.027694, "valtrna_c": -0.043435, "gdp_c": 2.0, "atp_c": -0.324, "pcollg_rest_c": 0.921682, "argtrna_c": -0.048116, "adp_c": 0.324, "trnaarg_c": 0.048116, "trnaasn_c": 0.033015, "trnacys_c": 0.027047, "lystrna_c": -0.036365, "trnaala_c": 0.072072, "trnalys_c": 0.036365, "asptrna_c": -0.049284, "trnaser_c": 0.051072, "trnagly_c": 0.195952, "pcollgpro_c": 0.072079, "alatrna_c": -0.072072, "glutrna_c": -0.049537, "pcollglys_c": 0.006239, "glntrna_c": -0.046288, "glytrna_c": -0.195952, "thrtrna_c": -0.042924, "trnapro_c": 0.167533, "protrna_c": -0.167533, "sertrna_c": -0.051072, "trnatyr_c": 0.022921, "trnatrp_c": 0.004785, "gtp_c": -2.0, "trnaleu_c": 0.033232, "asntrna_c": -0.033015, "pi_c": 2.324, "trnathr_c": 0.042924}, "id": "RCC0170", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Indole-3-acetate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"ind3ac_e": 1.0, "ind3ac_c": -1.0}, "id": "TCE7728", "gene_reaction_rule": ""}, {"subsystem": "Miscellaneous", "name": "inorganic triphosphatase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00138", "ec-code": "3.6.1.25", "sbo": "SBO:0000176"}, "metabolites": {"ppi_c": 1.0, "pppi_c": -1.0, "h2o_c": -1.0, "pi_c": 1.0, "h_c": 1.0}, "id": "RC00138", "gene_reaction_rule": ""}, {"subsystem": "Pentose phosphate pathway", "name": "ATP:D-Gluconate 6-phosphotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01737", "ec-code": "2.7.1.12", "sbo": "SBO:0000176"}, "metabolites": {"6pgc_c": 1.0, "glcn_c": -1.0, "adp_c": 1.0, "atp_c": -1.0, "h_c": 1.0}, "id": "RC01737", "gene_reaction_rule": "WBGene00017818"}, {"subsystem": "Protein modification by hydroxylation", "name": "artificial transformation of peptide to peptidyl-aspartate", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"h2o_c": 1.0, "pepasp_c": 1.0, "pepX_c": -1.0, "asp-L_c": -1.0}, "id": "RCC0178", "gene_reaction_rule": ""}, {"subsystem": "Alanine, aspartate and glutamate metabolism", "name": "L-Asparagine amidohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00485", "ec-code": "3.5.1.1", "sbo": "SBO:0000176"}, "metabolites": {"asn-L_c": -1.0, "h2o_c": -1.0, "nh4_c": 1.0, "asp-L_c": 1.0}, "id": "RC00485", "gene_reaction_rule": "WBGene00007756"}, {"subsystem": "Fructose and mannose metabolism", "name": "GDP:alpha-D-glucose 1-phosphate guanylyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R09752", "ec-code": "2.7.7.78", "sbo": "SBO:0000176"}, "metabolites": {"gdpg_c": -1.0, "pi_c": -1.0, "gdp_c": 1.0, "h_c": 1.0, "g1p_c": 1.0}, "id": "RC09752", "gene_reaction_rule": "WBGene00015678"}, {"subsystem": "beta-Alanine metabolism", "name": "L-aspartate 1-carboxy-lyase (beta-alanine-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00489", "ec-code": "4.1.1.15", "sbo": "SBO:0000176"}, "metabolites": {"ala-B_c": 1.0, "co2_c": 1.0, "h_c": -1.0, "asp-L_c": -1.0}, "id": "RC00489", "gene_reaction_rule": "WBGene00006762"}, {"subsystem": "Exchange with the environment", "name": "pantothenic acid uptake", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"pnto-R_e": -1.0}, "id": "EX00864", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Thymidine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"thymd_m": 1.0, "thymd_c": -1.0}, "id": "TCM0213", "gene_reaction_rule": ""}, {"subsystem": "Butanoate metabolism", "name": "Acetoacetate:CoA ligase (AMP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01357", "ec-code": "6.2.1.16", "sbo": "SBO:0000176"}, "metabolites": {"atp_c": -1.0, "ppi_c": 1.0, "aacoa_c": 1.0, "coa_c": -1.0, "amp_c": 1.0, "acac_c": -1.0}, "id": "RC01357", "gene_reaction_rule": "WBGene00006351"}, {"subsystem": "Exchange with the environment", "name": "D-Glucuronate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"glcur_e": -1.0}, "id": "EX00191", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "adenosylcobalamin exchange/defecation", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"adocbl_e": -1.0}, "id": "EX00194", "gene_reaction_rule": ""}, {"subsystem": "Glycolysis / Gluconeogenesis", "name": "ATP:beta-D-glucose 6-phosphotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01600", "ec-code": "2.7.1.1", "sbo": "SBO:0000176"}, "metabolites": {"h_c": 1.0, "g6p-B_c": 1.0, "glc-D-B_c": -1.0, "atp_c": -1.0, "adp_c": 1.0}, "id": "RC01600", "gene_reaction_rule": "WBGene00008780 or WBGene00010416 or WBGene00022306"}, {"subsystem": "Glycerolipid metabolism", "name": "1-acylglycerol acylhydrolase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01352", "ec-code": "3.1.1.23", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "Rtotal4_c": 1.0, "glyc_c": 1.0, "mag_c": -1.0, "h_c": 1.0}, "id": "RC01351", "gene_reaction_rule": "WBGene00022393"}, {"subsystem": "Glycolysis / Gluconeogenesis", "name": "D-Glucose 1-epimerase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01602", "ec-code": "5.1.3.3", "sbo": "SBO:0000176"}, "metabolites": {"glc-D-A_c": -1.0, "glc-D-B_c": 1.0}, "id": "RC01602", "gene_reaction_rule": "WBGene00015270 or WBGene00044734"}, {"subsystem": "Galactose metabolism", "name": "UDP-glucose:alpha-D-galactose-1-phosphate uridylyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00955", "ec-code": "2.7.7.12", "sbo": "SBO:0000176"}, "metabolites": {"udpgal_c": 1.0, "udpg_c": -1.0, "gal1p_c": -1.0, "g1p_c": 1.0}, "id": "RC00955", "gene_reaction_rule": "WBGene00014203"}, {"subsystem": "Transport", "name": "dUDP and dATP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"datp_c": -1.0, "dudp_m": -1.0, "dudp_c": 1.0, "datp_m": 1.0}, "id": "TCM0199", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "dADP and dCTP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dadp_c": 1.0, "dctp_c": -1.0, "dctp_m": 1.0, "dadp_m": -1.0}, "id": "TCM0198", "gene_reaction_rule": ""}, {"subsystem": "Tyrosine metabolism", "name": "L-tyrosine carboxy-lyase (tyramine-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00736", "ec-code": "4.1.1.28", "sbo": "SBO:0000176"}, "metabolites": {"tym_c": 1.0, "co2_c": 1.0, "h_c": -1.0, "tyr-L_c": -1.0}, "id": "RC00736", "gene_reaction_rule": "WBGene00006562"}, {"subsystem": "Transport", "name": "Acetate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"ac_c": -1.0, "ac_m": 1.0}, "id": "TCM0190", "gene_reaction_rule": ""}, {"subsystem": "Ubiquinone and other terpenoid-quinone biosynthesis", "name": "L-tyrosine:2-oxoglutarate aminotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00734", "ec-code": ["2.6.1.1", "2.6.1.5"], "sbo": "SBO:0000176"}, "metabolites": {"akg_c": -1.0, "glu-L_c": 1.0, "34hpp_c": 1.0, "tyr-L_c": -1.0}, "id": "RC00734", "gene_reaction_rule": "WBGene00020146 or WBGene00009628"}, {"subsystem": "Transport", "name": "beta-Alanine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"ala-B_c": -1.0, "ala-B_m": 1.0}, "id": "TCM0192", "gene_reaction_rule": ""}, {"subsystem": "Fatty acid elongation", "name": "trans-Hex-2-enoyl-CoA reductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R06985", "ec-code": "1.3.1.38", "sbo": "SBO:0000176"}, "metabolites": {"hxcoa_m": 1.0, "hx2coa_m": -1.0, "nadph_m": -1.0, "h_m": -1.0, "nadp_m": 1.0}, "id": "RM06985", "gene_reaction_rule": "WBGene00012375 or WBGene00012970"}, {"subsystem": "Primary bile acid biosynthesis", "name": "3beta-hydroxy-Delta5-C27-steroid oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R08724", "ec-code": "1.1.1.181", "sbo": "SBO:0000176"}, "metabolites": {"xoltri27_c": -1.0, "nadh_c": 1.0, "xol27one_c": 1.0, "h_c": 1.0, "nad_c": -1.0}, "id": "RC08724", "gene_reaction_rule": "WBGene00012394 or WBGene00022498 or WBGene00022616"}, {"subsystem": "Transport", "name": "Guanosine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"gsn_m": 1.0, "gsn_c": -1.0}, "id": "TCM0197", "gene_reaction_rule": ""}, {"subsystem": "Tyrosine metabolism", "name": "L-Tyrosine:oxygen oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00731", "ec-code": "1.14.18.1", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "34dhphe_c": 2.0, "tyr-L_c": -2.0}, "id": "RC00731", "gene_reaction_rule": "WBGene00015332 or WBGene00010661 or WBGene00009001 or WBGene00016419 or WBGene00021553 or WBGene00022231"}, {"subsystem": "Bacterial digestion", "name": "Bacterial phosphatidylserine degradation", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "3.1.1.4", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -3.0, "glyc_c": 1.0, "h_c": 3.0, "ps_BAC_c": -1.0, "Rtotal_BAC_c": 2.0, "pser-L_c": 1.0}, "id": "DGR0026", "gene_reaction_rule": "WBGene00019747 or WBGene00009801 or WBGene00012319 or WBGene00017026 or WBGene00019229 or WBGene00022233 or WBGene00011423 or WBGene00007419 or WBGene00044468"}, {"subsystem": "Bacterial digestion", "name": "Glycogen assimilation", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"glycogen_BAC_c": 1.0, "glycogen_BAC_e": -1.0}, "id": "DGR0027", "gene_reaction_rule": ""}, {"subsystem": "Bacterial digestion", "name": "Bacterial phosphatidate degradation", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "3.1.1.4", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -3.0, "glyc_c": 1.0, "h_c": 2.0, "pa_BAC_c": -1.0, "Rtotal_BAC_c": 2.0, "pi_c": 1.0}, "id": "DGR0024", "gene_reaction_rule": "WBGene00019747 or WBGene00009801 or WBGene00012319 or WBGene00017026 or WBGene00019229 or WBGene00022233 or WBGene00011423 or WBGene00007419 or WBGene00044468"}, {"subsystem": "Transport", "name": "phosphatidylcholine export", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"pchol_c": -1.0, "h2o_c": -1.0, "atp_c": -1.0, "pchol_e": 1.0, "h_c": 1.0, "adp_c": 1.0, "pi_c": 1.0}, "id": "TCE5122", "gene_reaction_rule": ""}, {"subsystem": "Bacterial digestion", "name": "Bacterial phosphatidylserine uptake", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"ps_BAC_e": -1.0, "ps_BAC_c": 1.0}, "id": "DGR0025", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Deoxyinosine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"din_c": 1.0, "din_e": -1.0}, "id": "TCE0441", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Urea transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"urea_c": 1.0, "urea_e": -1.0}, "id": "TCE0440", "gene_reaction_rule": ""}, {"subsystem": "Bacterial digestion", "name": "Bacterial phosphatidylglycerol uptake", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"pg_BAC_c": 1.0, "pg_BAC_e": -1.0}, "id": "DGR0020", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Formate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"for_m": -1.0, "for_c": 1.0}, "id": "TCM0064", "gene_reaction_rule": ""}, {"subsystem": "Glycine, serine and threonine metabolism", "name": "3-Phospho-D-glycerate:NAD+ 2-oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01513", "ec-code": "1.1.1.95", "sbo": "SBO:0000176"}, "metabolites": {"3php_c": 1.0, "nadh_c": 1.0, "h_c": 1.0, "nad_c": -1.0, "3pg_c": -1.0}, "id": "RC01513", "gene_reaction_rule": "WBGene00007836"}, {"subsystem": "Glycolysis / Gluconeogenesis", "name": "ATP:3-phospho-D-glycerate 1-phosphotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01512", "ec-code": "2.7.2.3", "sbo": "SBO:0000176"}, "metabolites": {"13dpg_c": 1.0, "adp_c": 1.0, "atp_c": -1.0, "3pg_c": -1.0}, "id": "RC01512", "gene_reaction_rule": "WBGene00020185"}, {"subsystem": "Glycine, serine and threonine metabolism", "name": "ATP:(R)-glycerate 3-phosphotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01514", "ec-code": "2.7.1.31", "sbo": "SBO:0000176"}, "metabolites": {"h_c": 1.0, "glyc-R_c": -1.0, "adp_c": 1.0, "atp_c": -1.0, "3pg_c": 1.0}, "id": "RC01514", "gene_reaction_rule": "WBGene00015733"}, {"subsystem": "Transport", "name": "Pyridoxal 5'-phosphate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"pydx5p_m": 1.0, "pydx5p_c": -1.0}, "id": "TCM0062", "gene_reaction_rule": ""}, {"subsystem": "Glycolysis / Gluconeogenesis", "name": "2-Phospho-D-glycerate 2,3-phosphomutase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01518", "ec-code": "5.4.2.12", "sbo": "SBO:0000176"}, "metabolites": {"2pg_c": -1.0, "3pg_c": 1.0}, "id": "RC01518", "gene_reaction_rule": "WBGene00019001"}, {"subsystem": "Primary bile acid biosynthesis", "name": "5beta-Cholestane-3alpha,7alpha,12alpha-triol,NADPH:oxygen oxidoreductase (26-hydroxylating)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R04807", "ec-code": "1.14.13.15", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "h2o_c": 1.0, "nadp_c": 1.0, "nadph_c": -1.0, "xoltetrol_c": 1.0, "h_c": -1.0, "xoltriol_c": -1.0}, "id": "RC04807", "gene_reaction_rule": "WBGene00000905"}, {"subsystem": "Transport", "name": "10-Formyltetrahydrofolate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"10fthf_m": 1.0, "10fthf_c": -1.0}, "id": "TCM0069", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Glyoxylate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"glx_e": -1.0}, "id": "EX00048", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "L-Aspartate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"asp-L_e": -1.0}, "id": "EX00049", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "L-Lysine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"lys-L_e": -1.0}, "id": "EX00047", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Succinate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"succ_e": -1.0}, "id": "EX00042", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "L-Alanine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"ala-L_e": -1.0}, "id": "EX00041", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Guanosine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"gsn_e": -1.0, "gsn_c": 1.0}, "id": "TCE0772", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Hexanoyl-CoA (n-C6:0CoA) exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"hxcoa_e": -1.0}, "id": "EX05270", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Pyridoxamine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"pydam_c": 1.0, "pydam_e": -1.0}, "id": "TCE0713", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "4-Hydroxyphenylacetate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"4hphac_c": -1.0, "4hphac_e": 1.0}, "id": "TCE0712", "gene_reaction_rule": ""}, {"subsystem": "Glycine, serine and threonine metabolism", "name": "L-Allothreonine acetaldehyde-lyase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R06171", "ec-code": "4.1.2.5", "sbo": "SBO:0000176"}, "metabolites": {"athr-L_c": -1.0, "acald_c": 1.0, "gly_c": 1.0}, "id": "RC06171", "gene_reaction_rule": "WBGene00011291"}, {"subsystem": "Transport", "name": "D-Lactate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"lac-D_c": 1.0, "lac-D_e": -1.0}, "id": "TCE0716", "gene_reaction_rule": ""}, {"subsystem": "Fatty acid elongation", "name": "(S)-3-Hydroxydodecanoyl-CoA hydro-lyase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R04170", "ec-code": "4.2.1.17", "sbo": "SBO:0000176"}, "metabolites": {"dd2coa_m": 1.0, "h2o_m": 1.0, "3hddcoa_m": -1.0}, "id": "RM04170", "gene_reaction_rule": "(WBGene00001155 or WBGene00001156) or (WBGene00020347 or WBGene00001150) or WBGene00001152"}, {"subsystem": "Exchange with the environment", "name": "Bilirubin beta-diglucuronide exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"bildglcur_e": -1.0}, "id": "EX05787", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "4-Aminobutanoate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"4abut_e": -1.0, "4abut_c": 1.0}, "id": "TCE0719", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "L-Methionine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"met-L_e": -1.0, "met-L_c": 1.0}, "id": "TCE0718", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "1-Methylnicotinamide exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"1mncam_e": -1.0}, "id": "EX02918", "gene_reaction_rule": ""}, {"subsystem": "Oxidative phosphorylation", "name": "Ubiquinol:ferricytochrome-c oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R02161", "ec-code": "1.10.2.2", "sbo": "SBO:0000176"}, "metabolites": {"qh2_m": -1.0, "ficytC_m": -2.0, "h_c": 4.0, "h_m": -2.0, "q_m": 1.0, "focytC_m": 2.0}, "id": "RM02161", "gene_reaction_rule": "WBGene00002162 and WBGene00000829 and WBGene00000869 and (WBGene00020757 or WBGene00012158 or WBGene00011679) and WBGene00012094 and WBGene00020181 and (WBGene00009739 or WBGene00019937) and WBGene00019007 and (WBGene00017121 or WBGene00013854)"}, {"subsystem": "Transport", "name": "L-Arabinitol transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"abt_c": 1.0, "abt_e": -1.0}, "id": "TCE1179", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Sodium exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"na1_e": -1.0}, "id": "EX01330", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Prostaglandin H2 transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"prostgh2_e": -1.0, "prostgh2_c": 1.0}, "id": "TCE5389", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "1-Alkyl-2-lyso-sn-glycero-3-phosphocholine uptake", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"ak2lgchol_e": -1.0, "ak2lgchol_c": 1.0}, "id": "TCE5388", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Deoxyribose exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"drib_e": -1.0}, "id": "EX01801", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "glucocerebroside  transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"gluside_ce_c": -1.0, "gluside_ce_e": 1.0}, "id": "TCE5383", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "phosphatidylglycerol  transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"pglyc_e": -1.0, "pglyc_c": 1.0}, "id": "TCE5382", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "triacylglycerol transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"tag_c": 1.0, "tag_e": -1.0}, "id": "TCE5381", "gene_reaction_rule": ""}, {"subsystem": "Miscellaneous", "name": "NADPH:oxygen oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R07172", "ec-code": "1.6.3.1", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "nadp_c": 1.0, "nadph_c": -1.0, "h_c": -1.0, "h2o2_c": 1.0}, "id": "RC07172", "gene_reaction_rule": "WBGene00000253 or WBGene00018771"}, {"subsystem": "Transport", "name": "1-Alkyl-2-lyso-sn-glycero-3-phosphocholine secretion", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"h2o_c": -1.0, "atp_c": -1.0, "ak2lgchol_e": 1.0, "ak2lgchol_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "pi_c": 1.0}, "id": "TCE5387", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Lysophosphatidylcholine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"lpchol_c": 1.0, "lpchol_e": -1.0}, "id": "TCE5386", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Platelet-activating factor uptake", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"paf_e": -1.0, "paf_c": 1.0}, "id": "TCE5385", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Platelet-activating factor secretion", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"paf_e": 1.0, "h2o_c": -1.0, "atp_c": -1.0, "paf_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "pi_c": 1.0}, "id": "TCE5384", "gene_reaction_rule": ""}, {"subsystem": "Pyrimidine metabolism", "name": "ATP:deoxyuridine 5-phosphotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02099", "ec-code": "2.7.1.21", "sbo": "SBO:0000176"}, "metabolites": {"h_c": 1.0, "dump_c": 1.0, "duri_c": -1.0, "atp_c": -1.0, "adp_c": 1.0}, "id": "RC02099", "gene_reaction_rule": "WBGene00006568"}, {"subsystem": "Pyrimidine metabolism", "name": "ATP:dUMP phosphotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R02098", "ec-code": "2.7.4.9", "sbo": "SBO:0000176"}, "metabolites": {"dudp_c": 1.0, "dump_c": -1.0, "atp_c": -1.0, "adp_c": 1.0}, "id": "RC02098", "gene_reaction_rule": "WBGene00011272"}, {"subsystem": "Exchange with the environment", "name": "Cardiolipin (bacteria) exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"clpn_BAC_e": -1.0}, "id": "EXC0063", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Superoxide anion transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"o2s_c": -1.0, "o2s_e": 1.0}, "id": "TCE0627", "gene_reaction_rule": ""}, {"subsystem": "Pyrimidine metabolism", "name": "ATP:dTMP phosphotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R02094", "ec-code": "2.7.4.9", "sbo": "SBO:0000176"}, "metabolites": {"dtmp_c": -1.0, "dtdp_c": 1.0, "adp_c": 1.0, "atp_c": -1.0}, "id": "RC02094", "gene_reaction_rule": "WBGene00011272"}, {"subsystem": "Purine metabolism", "name": "ATP:dGMP phosphotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R02090", "ec-code": "2.7.4.8", "sbo": "SBO:0000176"}, "metabolites": {"dgdp_c": 1.0, "dgmp_c": -1.0, "adp_c": 1.0, "atp_c": -1.0}, "id": "RC02090", "gene_reaction_rule": "WBGene00020190"}, {"subsystem": "Pyrimidine metabolism", "name": "ATP:dTDP phosphotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R02093", "ec-code": "2.7.4.6", "sbo": "SBO:0000176"}, "metabolites": {"dttp_c": 1.0, "dtdp_c": -1.0, "adp_c": 1.0, "atp_c": -1.0}, "id": "RC02093", "gene_reaction_rule": "WBGene00019899 or WBGene00021692 or WBGene00009119"}, {"subsystem": "Tryptophan metabolism", "name": "5-Hydroxy-L-tryptophan decarboxy-lyase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02701", "ec-code": "4.1.1.28", "sbo": "SBO:0000176"}, "metabolites": {"srtn_c": 1.0, "co2_c": 1.0, "h_c": -1.0, "5htrp_c": -1.0}, "id": "RC02701", "gene_reaction_rule": "WBGene00000239"}, {"subsystem": "Glycerolipid metabolism", "name": "acyl-CoA:1,2-diacyl-sn-glycerol O-acyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02251", "ec-code": "2.3.1.20", "sbo": "SBO:0000176"}, "metabolites": {"coa_c": 1.0, "tag_c": 1.0, "Rtotal3coa_c": -1.0, "dag_tag_c": -1.0}, "id": "RC02251", "gene_reaction_rule": "WBGene00010408"}, {"subsystem": "Glycerolipid metabolism", "name": "Triacylglycerol acylhydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R02250", "R01369"], "ec-code": ["3.1.1.3", "3.1.1.79"], "sbo": "SBO:0000176"}, "metabolites": {"Rtotal3_c": 1.0, "h2o_c": -1.0, "tag_c": -1.0, "h_c": 1.0, "dag_tag_c": 1.0}, "id": "RC02250", "gene_reaction_rule": "WBGene00015484 or WBGene00016704"}, {"subsystem": "Valine, leucine and isoleucine degradation", "name": "acetyl-CoA:propanoyl-CoA 2-C-acetyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00927", "ec-code": "2.3.1.16", "sbo": "SBO:0000176"}, "metabolites": {"accoa_m": 1.0, "ppcoa_m": 1.0, "coa_m": -1.0, "2maacoa_m": -1.0}, "id": "RM00927", "gene_reaction_rule": "WBGene00015125 or WBGene00009952"}, {"subsystem": "Tyrosine metabolism", "name": "L-Tyrosine,L-dopa:oxygen oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02078", "ec-code": "1.14.18.1", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "h2o_c": 2.0, "34dhphe_c": -2.0, "dopaqn_c": 2.0}, "id": "RC02078", "gene_reaction_rule": "WBGene00015332 or WBGene00010661 or WBGene00009001 or WBGene00016419 or WBGene00021553 or WBGene00022231"}, {"subsystem": "Miscellaneous", "name": "D-alanine:oxygen oxidoreductase (deaminating)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R05861", "ec-code": "1.4.3.3", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "ala-D_c": -1.0, "pyr_c": 1.0, "h2o_c": -1.0, "h2o2_c": 1.0, "nh4_c": 1.0}, "id": "RC05861", "gene_reaction_rule": "WBGene00022076"}, {"subsystem": "Transport", "name": "Na+/K+ exchanging ATPase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "3.6.3.9", "sbo": "SBO:0000185"}, "metabolites": {"h2o_c": -1.0, "atp_c": -1.0, "na1_c": -3.0, "na1_e": 3.0, "h_c": 1.0, "adp_c": 1.0, "k_c": 2.0, "pi_c": 1.0, "k_e": -2.0}, "id": "TCE5019", "gene_reaction_rule": "(WBGene00001137 or WBGene00007248 or WBGene00015660 or WBGene00015338 or WBGene00013672) and (WBGene00007646 or WBGene00008074 or WBGene00010117)"}, {"subsystem": "Transport", "name": "5-Methyltetrahydrofolate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"5mthf_e": -1.0, "5mthf_c": 1.0}, "id": "TCE0533", "gene_reaction_rule": ""}, {"subsystem": "Fatty acid metabolism", "name": "Decanoyl-CoA:(acceptor) 2,3-oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R04754", "ec-code": "1.3.8.7", "sbo": "SBO:0000176"}, "metabolites": {"dc2coa_m": 1.0, "dcacoa_m": -1.0, "etfox_m": -1.0, "etfrd_m": 1.0}, "id": "RM04754", "gene_reaction_rule": "(WBGene00020812 or WBGene00019406 or WBGene00020366)"}, {"subsystem": "Transport", "name": "thiamine uptake", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"thm_c": 1.0, "thm_e": -1.0}, "id": "TCE5017", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "gluconate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"glcn_c": 1.0, "glcn_e": -1.0}, "id": "TCE5016", "gene_reaction_rule": ""}, {"subsystem": "Fatty acid metabolism", "name": "Hexanoyl-CoA:(acceptor) 2,3-oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R04751", "ec-code": ["1.3.8.7", "1.3.8.1"], "sbo": "SBO:0000176"}, "metabolites": {"hxcoa_m": -1.0, "hx2coa_m": 1.0, "etfox_m": -1.0, "etfrd_m": 1.0}, "id": "RM04751", "gene_reaction_rule": "(WBGene00020812 or WBGene00019406 or WBGene00020366) or (WBGene00016943 or WBGene00015894)"}, {"subsystem": "Miscellaneous", "name": "Trihexosylceramide galactohydrolase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R03618", "ec-code": "3.2.1.22", "sbo": "SBO:0000176"}, "metabolites": {"galgluside_ce_c": 1.0, "h2o_c": -1.0, "gal_c": 1.0, "thcrm_ce_c": -1.0}, "id": "RC03618", "gene_reaction_rule": "WBGene00011095"}, {"subsystem": "Exchange with the environment", "name": "1-Acyl-sn-glycero-3-phosphoglycerol exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"lpglyc_e": -1.0}, "id": "EX18126", "gene_reaction_rule": ""}, {"subsystem": "Sphingolipid metabolism", "name": "D-galactosyl-N-acylsphingosine galactohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03617", "ec-code": "3.2.1.46", "sbo": "SBO:0000176"}, "metabolites": {"crm_ce_c": 1.0, "galside_ce_c": -1.0, "gal_c": 1.0, "h2o_c": -1.0}, "id": "RC03617", "gene_reaction_rule": "WBGene00016207"}, {"subsystem": "Aminoacyl-tRNA biosynthesis", "name": "Glu-tRNA(Gln):L-glutamine amido-ligase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R03905", "ec-code": "6.3.5.7", "sbo": "SBO:0000176"}, "metabolites": {"glu-L_m": 1.0, "atp_m": -1.0, "gln-L_m": -1.0, "h2o_m": -1.0, "glntrna_m": 1.0, "glutrna_gln_m": -1.0, "pi_m": 1.0, "adp_m": 1.0, "h_m": 1.0}, "id": "RM03905", "gene_reaction_rule": "WBGene00016524 and WBGene00013433 and WBGene00021508"}, {"subsystem": "Glycerophospholipid metabolism", "name": "Acyl-CoA:1-acyl-sn-glycero-3-phosphoethanolamine O-acyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R04480", "ec-code": "2.3.1.23", "sbo": "SBO:0000176"}, "metabolites": {"acg3pe_c": -1.0, "Rtotal2coa_c": -1.0, "coa_c": 1.0, "pe_c": 1.0}, "id": "RC04480", "gene_reaction_rule": "WBGene00020115 or (WBGene00016934 or WBGene00007446)"}, {"subsystem": "Transport", "name": "Androsterone transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"andrstrn_c": 1.0, "andrstrn_e": -1.0}, "id": "TCE0447", "gene_reaction_rule": ""}, {"subsystem": "Purine metabolism", "name": "1-(5-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole AMP-lyase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R04559", "ec-code": "4.3.2.2", "sbo": "SBO:0000176"}, "metabolites": {"25aics_c": -1.0, "fum_c": 1.0, "aicar_c": 1.0}, "id": "RC04559", "gene_reaction_rule": "WBGene00011064"}, {"subsystem": "Transport", "name": "phosphatidylcholine import", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"pchol_c": 1.0, "pchol_e": -1.0}, "id": "TCE5123", "gene_reaction_rule": ""}, {"subsystem": "Tryptophan metabolism", "name": "Hydroxyanthranilate oxidation", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R02670", "ec-code": "1.11.1.6", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -4.0, "3hanthrn_c": -2.0, "h2o2_c": 2.0, "h_c": 4.0, "cinnavalininate_c": 1.0, "o2s_c": 2.0}, "id": "RC02670", "gene_reaction_rule": "WBGene00000830 or WBGene00000831 or WBGene00013220"}, {"subsystem": "Ascaroside biosynthesis", "name": "ascr2 transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"ascr2_e": 1.0, "ascr2_c": -1.0}, "id": "TCE5121", "gene_reaction_rule": ""}, {"subsystem": "Ascaroside biosynthesis", "name": "ascr7 transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"ascr7_c": -1.0, "ascr7_e": 1.0}, "id": "TCE5120", "gene_reaction_rule": ""}, {"subsystem": "Tryptophan metabolism", "name": "Indole-3-acetaldehyde:NAD+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02678", "ec-code": "1.2.1.3", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "h_c": 2.0, "nad_c": -1.0, "nadh_c": 1.0, "ind3ac_c": 1.0, "id3acald_c": -1.0}, "id": "RC02678", "gene_reaction_rule": "(WBGene00000108 or WBGene00000110) or (WBGene00000117 or WBGene00000118)"}, {"subsystem": "Cysteine and methionine metabolism", "name": "3-Mercaptolactate:NAD+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R03104", "ec-code": "1.1.1.27", "sbo": "SBO:0000176"}, "metabolites": {"mercppyr_c": 1.0, "mercplac_c": -1.0, "nadh_c": 1.0, "h_c": 1.0, "nad_c": -1.0}, "id": "RC03104", "gene_reaction_rule": "WBGene00002262"}, {"subsystem": "Cysteine and methionine metabolism", "name": "3-Mercaptopyruvate:cyanide sulfurtransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R03105", "ec-code": "2.8.1.2", "sbo": "SBO:0000176"}, "metabolites": {"so3_c": -1.0, "tsul_c": 1.0, "pyr_c": 1.0, "mercppyr_c": -1.0}, "id": "RC03105", "gene_reaction_rule": "WBGene00008409 or WBGene00010380 or WBGene00010383 or WBGene00017387 or WBGene00022006 or WBGene00022007 or WBGene00011307"}, {"subsystem": "Miscellaneous", "name": "3-mercaptopyruvate:cyanide sulfurtransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03106", "ec-code": "2.8.1.2", "sbo": "SBO:0000176"}, "metabolites": {"pyr_c": 1.0, "tcynt_c": 1.0, "cyan_c": -1.0, "mercppyr_c": -1.0, "h_c": 1.0}, "id": "RC03106", "gene_reaction_rule": "WBGene00008409 or WBGene00010380 or WBGene00010383 or WBGene00017387 or WBGene00022006 or WBGene00022007 or WBGene00011307"}, {"subsystem": "Citrate cycle (TCA cycle)", "name": "Succinate:ubiquinone oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02164", "ec-code": "1.3.5.1", "sbo": "SBO:0000176"}, "metabolites": {"q_m": -1.0, "succ_m": -1.0, "qh2_m": 1.0, "fum_m": 1.0}, "id": "RM02164", "gene_reaction_rule": "((WBGene00015391 or WBGene00016392) and WBGene00006433) and WBGene00003225 and WBGene00009353"}, {"subsystem": "Phenylalanine metabolism", "name": "4a-hydroxytetrahydrobiopterin hydro-lyase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R04734", "ec-code": "4.2.1.96", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": 1.0, "thbpt4acam_c": -1.0, "dhbpt_c": 1.0}, "id": "RC04734", "gene_reaction_rule": "WBGene00020397"}, {"subsystem": "Exchange with the environment", "name": "N6,N6,N6-Trimethyl-L-lysine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"tmlys_e": -1.0}, "id": "EX03793", "gene_reaction_rule": ""}, {"subsystem": "Glutathione metabolism", "name": "5-oxo-L-proline amidohydrolase (ATP-hydrolysing)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00251", "ec-code": "3.5.2.9", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -2.0, "atp_c": -1.0, "glu-L_c": 1.0, "5oxpro_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "pi_c": 1.0}, "id": "RC00251", "gene_reaction_rule": "WBGene00021430"}, {"subsystem": "Alanine, aspartate and glutamate metabolism", "name": "L-Glutamate:ammonia ligase (ADP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00253", "ec-code": "6.3.1.2", "sbo": "SBO:0000176"}, "metabolites": {"atp_c": -1.0, "gln-L_c": 1.0, "glu-L_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "pi_c": 1.0, "nh4_c": -1.0}, "id": "RC00253", "gene_reaction_rule": "WBGene00001602 or WBGene00001603 or WBGene00001604 or WBGene00001606 or WBGene00001607"}, {"subsystem": "Nicotinate and nicotinamide metabolism", "name": "Deamido-NAD+:L-glutamine amido-ligase (AMP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00257", "ec-code": "6.3.5.1", "sbo": "SBO:0000176"}, "metabolites": {"dnad_c": -1.0, "h2o_c": -1.0, "atp_c": -1.0, "gln-L_c": -1.0, "glu-L_c": 1.0, "ppi_c": 1.0, "amp_c": 1.0, "nad_c": 1.0, "h_c": 1.0}, "id": "RC00257", "gene_reaction_rule": "WBGene00007698"}, {"subsystem": "Alanine, aspartate and glutamate metabolism", "name": "L-Glutamine amidohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00256", "ec-code": "3.5.1.2", "sbo": "SBO:0000176"}, "metabolites": {"glu-L_c": 1.0, "h2o_c": -1.0, "nh4_c": 1.0, "gln-L_c": -1.0}, "id": "RC00256", "gene_reaction_rule": "WBGene00007480 or WBGene00008435 or WBGene00009271"}, {"subsystem": "Carnitine shuttle", "name": "Carnitine-acylcarnitine translocase (translocating fa15p0isocrn)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"fa15p0isocrn_m": 1.0, "fa15p0isocrn_c": -1.0}, "id": "TCM5013", "gene_reaction_rule": "WBGene00000996 or WBGene00008320"}, {"subsystem": "Carnitine shuttle", "name": "Carnitine-acylcarnitine translocase (translocating fa19c11crn)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"fa19c11crn_c": -1.0, "fa19c11crn_m": 1.0}, "id": "TCM5012", "gene_reaction_rule": "WBGene00000996 or WBGene00008320"}, {"subsystem": "Carnitine shuttle", "name": "Carnitine-acylcarnitine translocase (translocating fa17c9crn)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"fa17c9crn_c": -1.0, "fa17c9crn_m": 1.0}, "id": "TCM5011", "gene_reaction_rule": "WBGene00000996 or WBGene00008320"}, {"subsystem": "Carnitine shuttle", "name": "Carnitine-acylcarnitine translocase (translocating fa11c3crn)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"fa11c3crn_c": -1.0, "fa11c3crn_m": 1.0}, "id": "TCM5010", "gene_reaction_rule": "WBGene00000996 or WBGene00008320"}, {"subsystem": "Carnitine shuttle", "name": "Carnitine-acylcarnitine translocase (translocating fa9p0isocrn)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"fa9p0isocrn_c": -1.0, "fa9p0isocrn_m": 1.0}, "id": "TCM5015", "gene_reaction_rule": "WBGene00000996 or WBGene00008320"}, {"subsystem": "Carnitine shuttle", "name": "Carnitine-acylcarnitine translocase (translocating fa17p0isocrn)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"fa17p0isocrn_c": -1.0, "fa17p0isocrn_m": 1.0}, "id": "TCM5014", "gene_reaction_rule": "WBGene00000996 or WBGene00008320"}, {"subsystem": "Transport", "name": "Vaccenic acid transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"vacc_e": -1.0, "vacc_c": 1.0}, "id": "TCE0576", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "thiamine transport to mitochondria", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"thmpp_c": -1.0, "thmpp_m": 1.0}, "id": "TCM5018", "gene_reaction_rule": ""}, {"subsystem": "Glycine, serine and threonine metabolism", "name": "p-Cumic alcohol:NADP+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02566", "ec-code": "1.2.1.8", "sbo": "SBO:0000176"}, "metabolites": {"glyb_m": 1.0, "nadph_m": 1.0, "h2o_m": -1.0, "nadp_m": -1.0, "betald_m": -1.0, "h_m": 2.0}, "id": "RM02566", "gene_reaction_rule": "WBGene00000115"}, {"subsystem": "Glycine, serine and threonine metabolism", "name": "p-Cumic alcohol:NADP+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02565", "ec-code": "1.2.1.8", "sbo": "SBO:0000176"}, "metabolites": {"glyb_m": 1.0, "h2o_m": -1.0, "nadh_m": 1.0, "nad_m": -1.0, "betald_m": -1.0, "h_m": 2.0}, "id": "RM02565", "gene_reaction_rule": "WBGene00000115"}, {"subsystem": "Valine, leucine and isoleucine degradation", "name": "Propanoyl-CoA:carbon-dioxide ligase (ADP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01859", "ec-code": "6.4.1.3", "sbo": "SBO:0000176"}, "metabolites": {"mmcoa-S_m": 1.0, "hco3_m": -1.0, "atp_m": -1.0, "adp_m": 1.0, "pi_m": 1.0, "ppcoa_m": -1.0, "h_m": 1.0}, "id": "RM01859", "gene_reaction_rule": "WBGene00017864 and WBGene00018701"}, {"subsystem": "Glycine, serine and threonine metabolism", "name": "L-Serine:pyruvate aminotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00585", "ec-code": "2.6.1.51", "sbo": "SBO:0000176"}, "metabolites": {"ala-L_m": 1.0, "pyr_m": -1.0, "ser-L_m": -1.0, "hpyr_m": 1.0}, "id": "RM00585", "gene_reaction_rule": "WBGene00011767"}, {"subsystem": "Retinol metabolism", "name": "beta-carotene 15,15'-monooxygenase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00032", "ec-code": "1.14.99.36", "sbo": "SBO:0000176"}, "metabolites": {"retinal_c": 2.0, "caro_c": -1.0, "o2_c": -1.0}, "id": "RC00032", "gene_reaction_rule": "WBGene00012914"}, {"subsystem": "Glycerophospholipid metabolism", "name": "sn-Glycero-3-phosphocholine glycerophosphohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01030", "ec-code": "3.1.4.46", "sbo": "SBO:0000176"}, "metabolites": {"chol_c": 1.0, "glyc3p_c": 1.0, "h2o_c": -1.0, "g3pc_c": -1.0, "h_c": 1.0}, "id": "RC01030", "gene_reaction_rule": "WBGene00020446 or WBGene00011929 or WBGene00022532"}, {"subsystem": "Glycerolipid metabolism", "name": "Glycerol:NAD+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01036", "ec-code": "1.1.1.21", "sbo": "SBO:0000176"}, "metabolites": {"glyc_c": 1.0, "nadh_c": -1.0, "glyald_c": -1.0, "nad_c": 1.0, "h_c": -1.0}, "id": "RC01036", "gene_reaction_rule": "WBGene00012722"}, {"subsystem": "Arginine and proline metabolism", "name": "N-Acetylputrescine:oxygen oxidoreductase (deaminating) (flavin-containing)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R04025", "ec-code": "1.4.3.4", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "h2o_c": -1.0, "n4abutn_c": 1.0, "aprut_c": -1.0, "h2o2_c": 1.0, "nh4_c": 1.0}, "id": "RC04025", "gene_reaction_rule": "WBGene00000138"}, {"subsystem": "Transport", "name": "Pantetheine 4'-phosphate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"pan4p_c": -1.0, "pan4p_m": 1.0}, "id": "TCM1039", "gene_reaction_rule": ""}, {"subsystem": "Peroxisomal fatty acid beta oxidation", "name": "Lauroyl-CoA:acetyl-CoA C-acyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03858", "ec-code": "2.3.1.16", "sbo": "SBO:0000176"}, "metabolites": {"ddcacoa_c": 1.0, "3otdcoa_c": -1.0, "coa_c": -1.0, "accoa_c": 1.0}, "id": "RC03858", "gene_reaction_rule": "WBGene00013284"}, {"subsystem": "Transport", "name": "Ammonium transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"nh4_m": 1.0, "nh4_c": -1.0}, "id": "TCM1031", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "4-Hydroxybenzoate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"4hbz_c": -1.0, "4hbz_m": 1.0}, "id": "TCM1033", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "5-Methyltetrahydrofolate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"5mthf_m": 1.0, "5mthf_c": -1.0}, "id": "TCM1035", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "3-Methyl-2-oxobutanoate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"3mob_m": 1.0, "3mob_c": -1.0}, "id": "TCM1034", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "3-(4-Hydroxyphenyl)pyruvate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"34hpp_c": -1.0, "34hpp_m": 1.0}, "id": "TCM1037", "gene_reaction_rule": ""}, {"subsystem": "Protein modification by hydroxylation", "name": "Peptide-L-aspartate,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "1.14.11.16", "sbo": "SBO:0000176"}, "metabolites": {"akg_c": -1.0, "o2_c": -1.0, "pepasn3oh_c": 1.0, "pepasn_c": -1.0, "succ_c": 1.0, "co2_c": 1.0}, "id": "RCC0180", "gene_reaction_rule": "WBGene00010703"}, {"subsystem": "Aminoacyl-tRNA biosynthesis", "name": "Selenocysteine:tRNASec ligase (AMP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "6.1.1.11", "sbo": "SBO:0000176"}, "metabolites": {"selcys_c": -1.0, "atp_c": -1.0, "ppi_c": 1.0, "sectrna_c": 1.0, "amp_c": 1.0, "trnasec_c": -1.0}, "id": "RCC0181", "gene_reaction_rule": "WBGene00005663"}, {"subsystem": "Terpenoid backbone biosynthesis", "name": "(2E,6E)-farnesyl-diphosphate:isopentenyl-diphosphate farnesyltranstransferase (adding 7 isopentenyl units)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R09249", "ec-code": "2.5.1.91", "sbo": "SBO:0000176"}, "metabolites": {"nonadp_c": 1.0, "ppi_c": 6.0, "ipdp_c": -6.0, "frdp_c": -1.0}, "id": "RCC0185", "gene_reaction_rule": "WBGene00000761"}, {"subsystem": "Nicotinate and nicotinamide metabolism", "name": "Nicotinate D-ribonucleotide:diphosphate phosphoribosyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01724", "ec-code": "6.3.4.21", "sbo": "SBO:0000176"}, "metabolites": {"nicrnt_c": 1.0, "ppi_c": 1.0, "h_c": -1.0, "prpp_c": -1.0, "nac_c": -1.0}, "id": "RC01724", "gene_reaction_rule": "WBGene00021882"}, {"subsystem": "Peroxisomal fatty acid beta oxidation", "name": "Palmitoyl-CoA oxidase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00388", "ec-code": "1.3.3.6", "sbo": "SBO:0000176"}, "metabolites": {"pmtcoa_c": -1.0, "o2_c": -1.0, "hdd2coa_c": 1.0, "h2o2_c": 1.0}, "id": "RCC0165", "gene_reaction_rule": "WBGene00008167 or WBGene00008564 or WBGene00008565 or WBGene00008566 or WBGene00008567 or WBGene00019060 or WBGene00010336"}, {"subsystem": "Peroxisomal fatty acid beta oxidation", "name": "Tetradecanoyl-CoA oxidase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00388", "ec-code": "1.3.3.6", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "td2coa_c": 1.0, "tdcoa_c": -1.0, "h2o2_c": 1.0}, "id": "RCC0166", "gene_reaction_rule": "WBGene00008167 or WBGene00008564 or WBGene00008565 or WBGene00008566 or WBGene00008567 or WBGene00019060 or WBGene00010336"}, {"subsystem": "Nicotinate and nicotinamide metabolism", "name": "NAD nucleosidase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00102", "ec-code": "3.5.1.-", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "ncam_c": 1.0, "adprib_c": 1.0, "nad_c": -1.0, "h_c": 1.0}, "id": "RC00102", "gene_reaction_rule": "WBGene00004800 or WBGene00004801 or WBGene00004802 or WBGene00004803"}, {"subsystem": "Cysteine and methionine metabolism", "name": "3-mercaptolactate:cysteine reductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"mercplaccys_c": 1.0, "mercplac_c": -1.0, "h_c": 1.0, "nad_c": -1.0, "cys-L_c": -1.0, "nadh_c": 1.0}, "id": "RCC0162", "gene_reaction_rule": ""}, {"subsystem": "Protein modification", "name": "O-acetyl-ADP-ribose deacetylase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "ac_c": 1.0, "adprib_c": 1.0, "ac_adprib_c": -1.0, "h_c": 1.0}, "id": "RCC0163", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "arachidonic acid exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"arachd_e": -1.0}, "id": "EX00219", "gene_reaction_rule": ""}, {"subsystem": "Peroxisomal fatty acid beta oxidation", "name": "Decanoyl-CoA oxidase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00388", "ec-code": "1.3.3.6", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "dc2coa_c": 1.0, "dcacoa_c": -1.0, "h2o2_c": 1.0}, "id": "RCC0168", "gene_reaction_rule": "WBGene00008167 or WBGene00008564 or WBGene00008565 or WBGene00008566 or WBGene00008567 or WBGene00019060 or WBGene00010336"}, {"subsystem": "Transport", "name": "Dihydroneopterin transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dhnpt_c": -1.0, "dhnpt_m": 1.0}, "id": "TCM1104", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "CMP transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"cmp_m": 1.0, "cmp_c": -1.0}, "id": "TCM1101", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "D-Erythrose 4-phosphate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"e4p_c": -1.0, "e4p_m": 1.0}, "id": "TCM1102", "gene_reaction_rule": ""}, {"subsystem": "Ascorbate and aldarate metabolism", "name": "uronolactonase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01483", "ec-code": "3.1.1.19", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": 1.0, "glcur_c": -1.0, "h_c": -1.0, "glac_c": 1.0}, "id": "RC01483", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "4-Hydroxy-2-oxoglutarate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"4h2oglt_m": 1.0, "4h2oglt_c": -1.0}, "id": "TCM1109", "gene_reaction_rule": ""}, {"subsystem": "Inositol phosphate metabolism", "name": "ATP:1D-myo-inositol-1,4,5-trisphosphate 3,6-phosphotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R10065", "ec-code": "2.7.1.151", "sbo": "SBO:0000176"}, "metabolites": {"mi13456p_c": 1.0, "mi145p_c": -1.0, "adp_c": 2.0, "atp_c": -2.0, "h_c": 2.0}, "id": "RC10065", "gene_reaction_rule": "WBGene00014081"}, {"subsystem": "Transport", "name": "4-Methyl-2-oxopentanoate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"4mop_e": -1.0, "4mop_c": 1.0}, "id": "TCE5359", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Ammonium exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"nh4_e": -1.0}, "id": "EX00014", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "cobalamin exchange/defecation", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"cbl1_e": -1.0}, "id": "EX00853", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "dUDP and ATP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"atp_m": -1.0, "dudp_m": 1.0, "dudp_c": -1.0, "atp_c": 1.0}, "id": "TCM0187", "gene_reaction_rule": ""}, {"subsystem": "Primary bile acid biosynthesis", "name": "alpha-methylacyl-CoA racemase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R08734", "ec-code": "5.1.99.4", "sbo": "SBO:0000176"}, "metabolites": {"cholcoas_c": 1.0, "cholcoar_c": -1.0}, "id": "RC08734", "gene_reaction_rule": "WBGene00016034 or WBGene00014128"}, {"subsystem": "Primary bile acid biosynthesis", "name": "Branched-chain acyl-CoA oxidase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R08735", "ec-code": "1.17.99.3", "sbo": "SBO:0000176"}, "metabolites": {"h2o2_c": 1.0, "o2_c": -1.0, "cholcoas_c": -1.0, "cholcoads_c": 1.0}, "id": "RC08735", "gene_reaction_rule": "WBGene00008564 or WBGene00008565 or WBGene00008566  or WBGene00008567  or WBGene00010336  or WBGene00008167 "}, {"subsystem": "Ubiquinone and other terpenoid-quinone biosynthesis", "name": "4-Coumarate:CoA ligase (AMP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01616", "ec-code": "6.2.1.12", "sbo": "SBO:0000176"}, "metabolites": {"atp_c": -1.0, "4cmcoa_c": 1.0, "ppi_c": 1.0, "T4hcinnm_c": -1.0, "coa_c": -1.0, "amp_c": 1.0}, "id": "RC01616", "gene_reaction_rule": "WBGene00022849 or WBGene00008669"}, {"subsystem": "Primary bile acid biosynthesis", "name": "bile acid CoA ligase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R08733", "ec-code": "6.2.1.7", "sbo": "SBO:0000176"}, "metabolites": {"atp_c": -1.0, "ppi_c": 1.0, "cholcoar_c": 1.0, "coa_c": -1.0, "amp_c": 1.0, "thcholstoic_c": -1.0}, "id": "RC08733", "gene_reaction_rule": "WBGene00009218 or WBGene00017012"}, {"subsystem": "Transport", "name": "Urocanate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"urcan_c": -1.0, "urcan_e": 1.0}, "id": "TCE5355", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "CO2 exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"co2_e": -1.0}, "id": "EX00011", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "dGDP and dCTP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dctp_m": 1.0, "dgdp_c": 1.0, "dgdp_m": -1.0, "dctp_c": -1.0}, "id": "TCM0188", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Uridine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"uri_c": -1.0, "uri_m": 1.0}, "id": "TCM0189", "gene_reaction_rule": ""}, {"subsystem": "Glycerophospholipid metabolism", "name": "ethanolamine-phosphate phosphate-lyase (deaminating) (acetaldehyde-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00748", "ec-code": "4.2.3.2", "sbo": "SBO:0000176"}, "metabolites": {"acald_c": 1.0, "h2o_c": -1.0, "pi_c": 1.0, "nh4_c": 1.0, "ethamp_c": -1.0}, "id": "RC00748", "gene_reaction_rule": "WBGene00020139"}, {"subsystem": "Exchange with the environment", "name": "dTTP exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"dttp_e": -1.0}, "id": "EX00459", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "D-Glucosamine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"gam_e": -1.0}, "id": "EX00329", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "L-Kynurenine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"Lkynr_e": -1.0}, "id": "EX00328", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "NMN exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"nmn_e": -1.0}, "id": "EX00455", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Homogentisate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"hgentis_e": -1.0}, "id": "EX00544", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "2-Oxoadipate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"2oxoadp_e": -1.0}, "id": "EX00322", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "3-Ureidoisobutyrate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"3uib_e": 1.0, "3uib_c": -1.0}, "id": "TCE5351", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "L-Arginine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"arg-L_c": -1.0, "arg-L_m": 1.0}, "id": "TCM0094", "gene_reaction_rule": ""}, {"subsystem": "Glycine, serine and threonine metabolism", "name": "L-serine hydro-lyase (adding homocysteine", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01290", "ec-code": "4.2.1.22", "sbo": "SBO:0000176"}, "metabolites": {"ser-L_c": -1.0, "cyst-L_c": 1.0, "h2o_c": 1.0, "hcys-L_c": -1.0}, "id": "RC01290", "gene_reaction_rule": "WBGene00013866 or WBGene00018783"}, {"subsystem": "Transport", "name": "Hydrogen peroxide transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"h2o2_c": -1.0, "h2o2_m": 1.0}, "id": "TCM0095", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "dUTP and dADP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dadp_c": 1.0, "dutp_m": 1.0, "dutp_c": -1.0, "dadp_m": -1.0}, "id": "TCM0097", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "S-Adenosyl-L-methionine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"amet_e": -1.0}, "id": "EX00019", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Superoxide anion transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"o2s_c": -1.0, "o2s_m": 1.0}, "id": "TCM0158", "gene_reaction_rule": ""}, {"subsystem": "Methane metabolism", "name": "S-(hydroxymethyl)glutathione dehydrogenase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R06983", "ec-code": "1.1.1.284", "sbo": "SBO:0000176"}, "metabolites": {"h_c": 1.0, "nadh_c": 1.0, "hmgth_c": -1.0, "nad_c": -1.0, "Sfglutth_c": 1.0}, "id": "RC06983", "gene_reaction_rule": "WBGene00019240"}, {"subsystem": "Methane metabolism", "name": "formaldehyde glutathione ligase (spontaneous)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R06982", "sbo": "SBO:0000176"}, "metabolites": {"gthrd_c": -1.0, "hmgth_c": 1.0, "fald_c": -1.0}, "id": "RC06982", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "L-Lactate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"lac-L_c": -1.0, "lac-L_m": 1.0}, "id": "TCM0093", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Pyridoxal 5'-phosphate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"pydx5p_e": -1.0}, "id": "EX00018", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Acetoacetate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"acac_c": -1.0, "acac_m": 1.0}, "id": "TCM0072", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Acetaldehyde transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"acald_c": 1.0, "acald_m": -1.0}, "id": "TCM0073", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "dTDP and dGTP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dtdp_m": -1.0, "dgtp_c": -1.0, "dtdp_c": 1.0, "dgtp_m": 1.0}, "id": "TCM0070", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "dUDP and dGDP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dgdp_c": 1.0, "dudp_m": 1.0, "dgdp_m": -1.0, "dudp_c": -1.0}, "id": "TCM0076", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Coenzyme A transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"coa_m": 1.0, "coa_c": -1.0}, "id": "TCM0077", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "L-Aspartate and 3-Sulfino-L-alanine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"asp-L_m": 1.0, "3sala_m": -1.0, "asp-L_c": -1.0, "3sala_c": 1.0}, "id": "TCM0075", "gene_reaction_rule": ""}, {"subsystem": "Histone modification", "name": "protein-N6-methyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R09511", "ec-code": "1.14.11.27", "sbo": "SBO:0000176"}, "metabolites": {"akg_c": -1.0, "o2_c": -1.0, "Nmelys_c": -1.0, "fald_c": 1.0, "succ_c": 1.0, "co2_c": 1.0, "Nlys_c": 1.0}, "id": "RC09511", "gene_reaction_rule": "WBGene00020821"}, {"subsystem": "Histone modification", "name": "protein-N6,N6-dimethyl-L-lysine,2-oxoglutarate:oxygen oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R09510", "ec-code": "1.14.11.27", "sbo": "SBO:0000176"}, "metabolites": {"akg_c": -1.0, "o2_c": -1.0, "Nmelys_c": 1.0, "Ndmelys_c": -1.0, "fald_c": 1.0, "succ_c": 1.0, "co2_c": 1.0}, "id": "RC09510", "gene_reaction_rule": "WBGene00020821"}, {"subsystem": "Transport", "name": "Phosphatidylethanolamine (bacteria) transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"pe_BAC_m": 1.0, "pe_BAC_c": -1.0}, "id": "TCM0078", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "dADP and ATP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"atp_m": -1.0, "dadp_c": -1.0, "atp_c": 1.0, "dadp_m": 1.0}, "id": "TCM0079", "gene_reaction_rule": ""}, {"subsystem": "Sphingolipid metabolism", "name": "UDP-alpha-D-galactose:N-acylsphingosine D-galactosyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01500", "ec-code": "2.7.1.47", "sbo": "SBO:0000176"}, "metabolites": {"h_c": 1.0, "udpgal_c": -1.0, "udp_c": 1.0, "galside_ce_c": 1.0, "crm_ce_c": -1.0}, "id": "RC01500", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "L-Cysteate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"Lcyst_e": -1.0}, "id": "EX00506", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Acetate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"ac_e": -1.0}, "id": "EX00033", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Protoheme exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"pheme_e": -1.0}, "id": "EX00032", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "D-Glucose exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"glc-D_e": -1.0}, "id": "EX00031", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Glycine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"gly_e": -1.0}, "id": "EX00037", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Deoxyuridine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"duri_e": -1.0}, "id": "EX00526", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Acetoacetate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"acac_c": 1.0, "acac_e": -1.0}, "id": "TCE0706", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Cholate transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"h2o_c": -1.0, "atp_c": -1.0, "cholate_e": 1.0, "cholate_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "pi_c": 1.0}, "id": "TCE0707", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "5-Formyltetrahydrofolate and hydroxide ion transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"5fthf_c": 1.0, "oh1_c": -1.0, "5fthf_e": -1.0, "oh1_e": 1.0}, "id": "TCE0709", "gene_reaction_rule": ""}, {"subsystem": "Tryptophan metabolism", "name": "5-Hydroxyindoleacetaldehyde:NAD+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R04903", "ec-code": "1.2.1.3", "sbo": "SBO:0000176"}, "metabolites": {"5hoxindoa_c": 1.0, "h2o_c": -1.0, "5hoxindact_c": -1.0, "h_c": 2.0, "nad_c": -1.0, "nadh_c": 1.0}, "id": "RC04903", "gene_reaction_rule": "(WBGene00000108 or WBGene00000110) or (WBGene00000117 or WBGene00000118)"}, {"subsystem": "Glutathione metabolism", "name": "glutathione:NADP+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00115", "ec-code": "1.8.1.7", "sbo": "SBO:0000176"}, "metabolites": {"gthox_m": -1.0, "nadph_m": -1.0, "h_m": -1.0, "gthrd_m": 2.0, "nadp_m": 1.0}, "id": "RM00115", "gene_reaction_rule": "WBGene00014028"}, {"subsystem": "Nicotinate and nicotinamide metabolism", "name": "NADPH:NAD+ oxidoreductase", "upper_bound": 0.0, "lower_bound": 0.0, "annotation": {"kegg.reaction": "R00112", "ec-code": "1.6.1.2", "sbo": "SBO:0000176"}, "metabolites": {"nad_m": 1.0, "nadph_m": 1.0, "nadh_m": -1.0, "nadp_m": -1.0}, "id": "RM00112", "gene_reaction_rule": "WBGene00003778"}, {"subsystem": "Exchange with the environment", "name": "Adenine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"ade_e": -1.0}, "id": "EX00147", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Oxidized glutathione transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"gthox_e": -1.0, "gthox_c": 1.0}, "id": "TCE1148", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "hydroxide ion exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"oh1_e": -1.0}, "id": "EX01328", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "3-Methyl-2-oxobutanoate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"3mob_e": -1.0}, "id": "EX00141", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "N-acetylglucosamine uptake", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"acgam_e": -1.0}, "id": "EX00140", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "potassium transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"k_c": 1.0, "k_e": -1.0}, "id": "TCE1143", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "L-Malate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"mal-L_e": -1.0}, "id": "EX00149", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "L-Proline exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"pro-L_e": -1.0}, "id": "EX00148", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Sphinganine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"sphgn_ce_c": 1.0, "sphgn_ce_e": -1.0}, "id": "TCE5398", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Sphingosine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"sphings_ce_e": 1.0, "sphings_ce_c": -1.0}, "id": "TCE5399", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Deoxyinosine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"din_e": -1.0}, "id": "EX05512", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "w-hydroxyl leukotriene B4 secretion", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"h2o_c": -1.0, "leuktrB4woh_e": 1.0, "atp_c": -1.0, "leuktrB4woh_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "pi_c": 1.0}, "id": "TCE5390", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "monoacylglycerol 2  transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"mag_e": -1.0, "mag_c": 1.0}, "id": "TCE5391", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Leukotriene B4 transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"leuktrB4_e": -1.0, "leuktrB4_c": 1.0}, "id": "TCE5392", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "5-Hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"5HPET_e": 1.0, "5HPET_c": -1.0}, "id": "TCE5393", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Leukotriene A4 transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"leuktrA4_e": -1.0, "leuktrA4_c": 1.0}, "id": "TCE5394", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "R total 2 position transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"Rtotal2_c": 1.0, "Rtotal2_e": -1.0}, "id": "TCE5395", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "R total transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"Rtotal_e": -1.0, "Rtotal_c": 1.0}, "id": "TCE5396", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "gamma-L-Glutamyl-L-cysteine secretion", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"h2o_c": -1.0, "pi_c": 1.0, "atp_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "glucys_c": -1.0, "glucys_e": 1.0}, "id": "TCE5397", "gene_reaction_rule": ""}, {"subsystem": "N-Glycan biosynthesis", "name": "alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R05985", "ec-code": "2.4.1.143", "sbo": "SBO:0000176"}, "metabolites": {"uacgam_c": -1.0, "n2m2masn_c": 1.0, "udp_c": 1.0, "nm2masn_c": -1.0, "h_c": 1.0}, "id": "RC05985", "gene_reaction_rule": "WBGene00001645"}, {"subsystem": "N-Glycan biosynthesis", "name": "mannosyl-oligosaccharide 1,2-alpha-mannosidase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R05982", "ec-code": "3.2.1.113", "sbo": "SBO:0000176"}, "metabolites": {"m4masn_c": 1.0, "h2o_c": -4.0, "m8masn_c": -1.0, "man_c": 4.0}, "id": "RC05982", "gene_reaction_rule": "WBGene00008411 or WBGene00008258 or WBGene00020197 or WBGene00013881"}, {"subsystem": "N-Glycan biosynthesis", "name": "alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R05983", "ec-code": "2.4.1.101", "sbo": "SBO:0000176"}, "metabolites": {"m4masn_c": -1.0, "uacgam_c": -1.0, "udp_c": 1.0, "h_c": 1.0, "nm4masn_c": 1.0}, "id": "RC05983", "gene_reaction_rule": "WBGene00001637 or WBGene00001638 or WBGene00001639"}, {"subsystem": "N-Glycan biosynthesis", "name": "glucan 1,3-alpha-glucosidase (acting on g2m8masn)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R05980", "ec-code": "3.2.1.84", "sbo": "SBO:0000176"}, "metabolites": {"g2m8masn_c": -1.0, "h2o_c": -1.0, "g1m8masn_c": 1.0, "glc-D_c": 1.0}, "id": "RC05980", "gene_reaction_rule": "WBGene00009583 or WBGene00018682"}, {"subsystem": "N-Glycan biosynthesis", "name": "glucan 1,3-alpha-glucosidase (acting on g1m8masn)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R05981", "ec-code": "3.2.1.84", "sbo": "SBO:0000176"}, "metabolites": {"g1m8masn_c": -1.0, "m8masn_c": 1.0, "h2o_c": -1.0, "glc-D_c": 1.0}, "id": "RC05981", "gene_reaction_rule": "WBGene00009583 or WBGene00018682"}, {"subsystem": "N-Glycan biosynthesis", "name": "glycoprotein 6-alpha-L-fucosyltransferase (acting on n2m2masn)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R05988", "ec-code": "2.4.1.68", "sbo": "SBO:0000176"}, "metabolites": {"n2m2masn_c": -1.0, "gdpfuc_c": -1.0, "gdp_c": 1.0, "h_c": 1.0, "fn2m2masn_c": 1.0}, "id": "RC05988", "gene_reaction_rule": "WBGene00001508"}, {"subsystem": "N-Glycan biosynthesis", "name": "UDP-galactose:N-acetyl-beta-D-glucosaminylglycopeptide beta-1,4-galactosyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R05989", "ec-code": "2.4.1.38", "sbo": "SBO:0000176"}, "metabolites": {"udpgal_c": -2.0, "udp_c": 2.0, "l2fn2m2masn_c": 1.0, "h_c": 2.0, "fn2m2masn_c": -1.0}, "id": "RC05989", "gene_reaction_rule": "WBGene00000269"}, {"subsystem": "Purine metabolism", "name": "2-Deoxyadenosine 5-monophosphate phosphohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02088", "ec-code": "3.1.3.5", "sbo": "SBO:0000176"}, "metabolites": {"damp_c": -1.0, "dad-2_c": 1.0, "h2o_c": -1.0, "pi_c": 1.0}, "id": "RC02088", "gene_reaction_rule": "WBGene00017775 or WBGene00012423 or WBGene00022201"}, {"subsystem": "Terpenoid backbone biosynthesis", "name": "(R)-Mevalonate:NADP+ oxidoreductase (CoA acylating)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R02082", "ec-code": "1.1.1.34", "sbo": "SBO:0000176"}, "metabolites": {"nadp_c": 2.0, "nadph_c": -2.0, "hmgcoa_c": -1.0, "mev-R_c": 1.0, "h_c": -2.0, "coa_c": 1.0}, "id": "RC02082", "gene_reaction_rule": "WBGene00017268"}, {"subsystem": "Tyrosine metabolism", "name": "3,4-Dihydroxy-L-phenylalanine carboxy-lyase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02080", "ec-code": "4.1.1.28", "sbo": "SBO:0000176"}, "metabolites": {"co2_c": 1.0, "34dhphe_c": -1.0, "dopa_c": 1.0, "h_c": -1.0}, "id": "RC02080", "gene_reaction_rule": "WBGene00000239"}, {"subsystem": "One carbon pool by folate", "name": "5,10-methylenetetrahydrofolate:NADP+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01220", "ec-code": "1.5.1.5", "sbo": "SBO:0000176"}, "metabolites": {"mlthf_m": -1.0, "nadph_m": 1.0, "methf_m": 1.0, "nadp_m": -1.0}, "id": "RM01220", "gene_reaction_rule": "WBGene00019492"}, {"subsystem": "Purine metabolism", "name": "Xanthosine 5-phosphate phosphohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02719", "ec-code": "3.1.3.5", "sbo": "SBO:0000176"}, "metabolites": {"xmp_c": -1.0, "h2o_c": -1.0, "pi_c": 1.0, "xtsn_c": 1.0}, "id": "RC02719", "gene_reaction_rule": "WBGene00017775 or WBGene00012423 or WBGene00022201"}, {"subsystem": "Exchange with the environment", "name": "glycocholate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"gchola_e": -1.0}, "id": "EX01921", "gene_reaction_rule": ""}, {"subsystem": "Terpenoid backbone biosynthesis", "name": "ATP:(R)-mevalonate 5-phosphotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02245", "ec-code": "2.7.1.36", "sbo": "SBO:0000176"}, "metabolites": {"5pmev_c": 1.0, "mev-R_c": -1.0, "adp_c": 1.0, "atp_c": -1.0, "h_c": 1.0}, "id": "RC02245", "gene_reaction_rule": "WBGene00021534"}, {"subsystem": "Glycerolipid metabolism", "name": "ATP:1,2-diacylglycerol 3-phosphotransferase (acting on phospholipid components)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02240", "ec-code": "2.7.1.107", "sbo": "SBO:0000176"}, "metabolites": {"dag_pl_c": -1.0, "pa_pl_c": 1.0, "adp_c": 1.0, "atp_c": -1.0, "h_c": 1.0}, "id": "RC02240", "gene_reaction_rule": "WBGene00000958 or WBGene00000959 or WBGene00000960 or WBGene00006483 or WBGene00019428"}, {"subsystem": "Glycerolipid metabolism", "name": "acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase (Rtotal2 group)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02241", "ec-code": "2.3.1.51", "sbo": "SBO:0000176"}, "metabolites": {"pa_pl_c": 1.0, "Rtotal2coa_c": -1.0, "coa_c": 1.0, "alpa_pl_c": -1.0}, "id": "RC02241", "gene_reaction_rule": "((WBGene00020264 or WBGene00022646 or WBGene00044631) or (WBGene00010339 or WBGene00011543) or (WBGene00016934 or WBGene00007446)) or WBGene00017888"}, {"subsystem": "Fatty acid elongation", "name": "3-hydroxyacyl-CoA dehydratase 2", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R07760", "ec-code": "4.2.1.134", "sbo": "SBO:0000176"}, "metabolites": {"3hodcoa_c": -1.0, "h2o_c": 1.0, "od2coa_c": 1.0}, "id": "RC07760", "gene_reaction_rule": "WBGene00020517"}, {"subsystem": "Fatty acid elongation", "name": " very-long-chain enoyl-CoA reductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R07761", "ec-code": "1.3.1.93", "sbo": "SBO:0000176"}, "metabolites": {"stcoa_c": 1.0, "od2coa_c": -1.0, "nadp_c": 1.0, "nadph_c": -1.0, "h_c": -1.0}, "id": "RC07761", "gene_reaction_rule": "WBGene00000198"}, {"subsystem": "Selenocompound metabolism", "name": "L-selenocysteine selenide-lyase (L-alanine-forming)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R03599", "ec-code": "4.4.1.16", "sbo": "SBO:0000176"}, "metabolites": {"selcys_c": -1.0, "seln_c": 1.0, "pydx5p_c": 1.0, "ala-L_c": 1.0, "pdx5p_c": -1.0, "h_c": 1.0}, "id": "RC03599", "gene_reaction_rule": "WBGene00017442"}, {"subsystem": "Terpenoid backbone biosynthesis", "name": "geranylgeranyl diphosphate synthase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02061", "ec-code": "2.5.1.29", "sbo": "SBO:0000176"}, "metabolites": {"ppi_c": 1.0, "ipdp_c": -1.0, "frdp_c": -1.0, "ttc-ggdp_c": 1.0}, "id": "RC02061", "gene_reaction_rule": "WBGene00000761 or WBGene00011058"}, {"subsystem": "Valine, leucine and isoleucine degradation", "name": "(S)-Methylmalonate semialdehyde:NAD+ oxidoreductase (CoA-propanoylating)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00935", "ec-code": "1.2.1.27", "sbo": "SBO:0000176"}, "metabolites": {"2mop_m": -1.0, "ppcoa_m": 1.0, "co2_m": 1.0, "nad_m": -1.0, "coa_m": -1.0, "nadh_m": 1.0}, "id": "RM00935", "gene_reaction_rule": "WBGene00000114"}, {"subsystem": "Selenocompound metabolism", "name": "Hydrogen selenide:NADP+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R03596", "ec-code": "1.8.1.9", "sbo": "SBO:0000176"}, "metabolites": {"seln_c": -1.0, "nadp_c": -3.0, "nadph_c": 3.0, "h2o_c": -3.0, "selnt_c": 1.0, "h_c": 4.0}, "id": "RC03596", "gene_reaction_rule": "WBGene00015553"}, {"subsystem": "Selenocompound metabolism", "name": "ATP:selenide, water phosphotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03595", "ec-code": "2.7.9.3", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "atp_c": -1.0, "seln_c": -1.0, "selnp_c": 1.0, "amp_c": 1.0, "pi_c": 1.0}, "id": "RC03595", "gene_reaction_rule": "WBGene00012867"}, {"subsystem": "Transport", "name": "Hexanoyl-CoA (n-C6:0CoA) transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"hxcoa_e": 1.0, "hxcoa_c": -1.0}, "id": "TCE5380", "gene_reaction_rule": ""}, {"subsystem": "Oxidative phosphorylation", "name": "NADH:rhodoquinone oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00281", "ec-code": ["1.6.5.3", "1.6.99.3"], "sbo": "SBO:0000176"}, "metabolites": {"h_c": 4.0, "nad_m": 1.0, "rq9_m": -1.0, "h_m": -5.0, "rq9h2_m": 1.0, "nadh_m": -1.0}, "id": "RMC0184", "gene_reaction_rule": "(WBGene00010959 and WBGene00010961 and WBGene00010966 and WBGene00010963 and WBGene00010967 and WBGene00010957 and WBGene00010958) and (WBGene00009992 and (WBGene00001520 or WBGene00006463) and WBGene00020417 and WBGene00003831 and WBGene00021562 and WBGene00012376 and WBGene00020636 and WBGene00003061 and WBGene00021839 and WBGene00009051) and (WBGene00009294 and WBGene00013406 and WBGene00007880 and WBGene00013308 and WBGene00009740 and WBGene00021849 and WBGene00021800 and WBGene00019401 and (WBGene00018151 or WBGene00013237) and WBGene00016393) and (WBGene00009712 and WBGene00007684 and WBGene00012166 and WBGene00016118 and WBGene00014086 and WBGene00008414 and WBGene00013094 and WBGene00015810 and WBGene00010326 and WBGene00022169 and WBGene00018361)"}, {"subsystem": "Oxidative phosphorylation", "name": "Uncoupling ATP synthesis from electron transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"h_m": 1.0, "h_c": -1.0}, "id": "RMC0187", "gene_reaction_rule": "WBGene00006729"}, {"subsystem": "Ubiquinone and other terpenoid-quinone biosynthesis", "name": "rhodoquinone-9 biosynthesis", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"q9_m": -1.0, "h2o_m": -1.0, "nh4_m": -1.0, "co2_m": 1.0, "nad_m": -3.0, "rq9_m": 1.0, "h_m": 4.0, "nadh_m": 3.0}, "id": "RMC0182", "gene_reaction_rule": ""}, {"subsystem": "Citrate cycle (TCA cycle)", "name": "fumarate reductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02164", "ec-code": "1.3.5.4", "sbo": "SBO:0000176"}, "metabolites": {"rq9_m": 1.0, "succ_m": 1.0, "rq9h2_m": -1.0, "fum_m": -1.0}, "id": "RMC0183", "gene_reaction_rule": "WBGene00018610"}, {"subsystem": "Tryptophan metabolism", "name": "4-(2-Aminophenyl)-2,4-dioxobutanoate dehydratase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03445", "sbo": "SBO:0000176"}, "metabolites": {"kynate_c": 1.0, "h2o_c": 1.0, "4aphdob_c": -1.0}, "id": "RC03445", "gene_reaction_rule": ""}, {"subsystem": "Citrate cycle (TCA cycle)", "name": "(S)-malate hydro-lyase (fumarate-forming)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01082", "ec-code": "4.2.1.2", "sbo": "SBO:0000176"}, "metabolites": {"h2o_m": 1.0, "fum_m": 1.0, "mal-L_m": -1.0}, "id": "RM01082", "gene_reaction_rule": "WBGene00001503"}, {"subsystem": "Glycerophospholipid metabolism", "name": "sn-Glycerol-3-phosphate:NAD+ 2-oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00842", "ec-code": "1.1.1.8", "sbo": "SBO:0000176"}, "metabolites": {"nad_m": 1.0, "h_m": -1.0, "glyc3p_m": 1.0, "dhap_m": -1.0, "nadh_m": -1.0}, "id": "RM00842", "gene_reaction_rule": "WBGene00010778"}, {"subsystem": "Transport", "name": "L-Tyrosine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"tyr-L_e": -1.0, "tyr-L_c": 1.0}, "id": "TCE0521", "gene_reaction_rule": ""}, {"subsystem": "Vitamin B12 metabolism", "name": "cobalamin transport into cytosol", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"h2o_c": -1.0, "atp_c": -1.0, "cbl1_c": 1.0, "cbl1_e": -1.0, "h_c": 1.0, "adp_c": 1.0, "pi_c": 1.0}, "id": "TCE5004", "gene_reaction_rule": ""}, {"subsystem": "Vitamin B12 metabolism", "name": "adenosylcobalamin transport into cytosol", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"h2o_c": -1.0, "atp_c": -1.0, "adocbl_c": 1.0, "adocbl_e": -1.0, "h_c": 1.0, "adp_c": 1.0, "pi_c": 1.0}, "id": "TCE5005", "gene_reaction_rule": ""}, {"subsystem": "Iron metabolism", "name": "heme transport into intestine", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"pheme_e": -1.0, "pheme_c": 1.0}, "id": "TCE5006", "gene_reaction_rule": "WBGene00019830 or WBGene00009493"}, {"subsystem": "Cyanoamino acid metabolism", "name": "beta cyanoalanine transport to and from cytosol", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"cyanala_c": 1.0, "cyanala_e": -1.0}, "id": "TCE5007", "gene_reaction_rule": ""}, {"subsystem": "Galactose metabolism", "name": "sucrose glucohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00801", "ec-code": "3.2.1.20", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "sucr_c": -1.0, "glc-D_c": 1.0, "fru_c": 1.0}, "id": "RC00801", "gene_reaction_rule": "WBGene00017071 or WBGene00019895"}, {"subsystem": "Valine, leucine and isoleucine degradation", "name": "L-Isoleucine:2-oxoglutarate aminotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R02199", "ec-code": "2.6.1.42", "sbo": "SBO:0000176"}, "metabolites": {"ile-L_m": -1.0, "glu-L_m": 1.0, "akg_m": -1.0, "3mop_m": 1.0}, "id": "RM02199", "gene_reaction_rule": "WBGene00001149 or WBGene00012855"}, {"subsystem": "Transport", "name": "Bicarbonate and Chloride transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"cl_e": -2.0, "cl_c": 2.0, "hco3_e": 1.0, "hco3_c": -1.0}, "id": "TCE0457", "gene_reaction_rule": ""}, {"subsystem": "Miscellaneous", "name": "Electron-transferring-flavoprotein:ubiquinone oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R04433", "ec-code": "1.5.5.1", "sbo": "SBO:0000176"}, "metabolites": {"q_m": -1.0, "qh2_m": 1.0, "etfox_m": 1.0, "etfrd_m": -1.0}, "id": "RM04433", "gene_reaction_rule": "WBGene00002855 and (WBGene00009187 and WBGene00017734)"}, {"subsystem": "Propanoate metabolism", "name": "Propanoyl-CoA:(acceptor) 2,3-oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R04432", "ec-code": "1.3.8.1", "sbo": "SBO:0000176"}, "metabolites": {"ppcoa_m": -1.0, "prpncoa_m": 1.0, "etfox_m": -1.0, "etfrd_m": 1.0}, "id": "RM04432", "gene_reaction_rule": "WBGene00016943"}, {"subsystem": "Primary bile acid biosynthesis", "name": "choloyl-CoA hydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R07296", "ec-code": "3.1.2.27", "sbo": "SBO:0000176"}, "metabolites": {"cholcoa_c": -1.0, "h2o_c": -1.0, "coa_c": 1.0, "h_c": 1.0, "cholate_c": 1.0}, "id": "RC07296", "gene_reaction_rule": "WBGene00017781"}, {"subsystem": "Tryptophan metabolism", "name": "3-Hydroxyanthranilate:oxygen 3,4-oxidoreductase (decyclizing)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02665", "ec-code": "1.13.11.6", "sbo": "SBO:0000176"}, "metabolites": {"3hanthrn_c": -1.0, "o2_c": -1.0, "cmusa_c": 1.0, "h_c": 1.0}, "id": "RC02665", "gene_reaction_rule": "WBGene00010595"}, {"subsystem": "Inositol phosphate metabolism", "name": "1-phosphatidyl-1D-myo-inositol-3,4-bisphosphate 4-phosphohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R07299", "ec-code": "3.1.3.66", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "pi_c": 1.0, "pail3p_c": 1.0, "pail34p_c": -1.0}, "id": "RC07299", "gene_reaction_rule": "WBGene00010975"}, {"subsystem": "Tryptophan metabolism", "name": "3-Hydroxy-L-kynurenine hydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02668", "ec-code": "3.7.1.3", "sbo": "SBO:0000176"}, "metabolites": {"3hanthrn_c": 1.0, "ala-L_c": 1.0, "h2o_c": -1.0, "hLkynr_c": -1.0}, "id": "RC02668", "gene_reaction_rule": "WBGene00015802"}, {"subsystem": "Taurine and hypotaurine metabolism", "name": "(5-L-glutamyl)-peptide:taurine 5-glutamyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01687", "ec-code": "2.3.2.2", "sbo": "SBO:0000176"}, "metabolites": {"gthrd_c": -1.0, "taur_c": -1.0, "glutaur_c": 1.0, "cgly_c": 1.0}, "id": "RC01687", "gene_reaction_rule": "WBGene00016906 or WBGene00019204 or WBGene00011393 or WBGene00020590 or WBGene00012416 or WBGene00022397"}, {"subsystem": "Arginine and proline metabolism", "name": "L-Ornithine:2-oxo-acid aminotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00667", "ec-code": "2.6.1.13", "sbo": "SBO:0000176"}, "metabolites": {"orn_m": -1.0, "glu-L_m": 1.0, "akg_m": -1.0, "glu5sa_m": 1.0}, "id": "RM00667", "gene_reaction_rule": "WBGene00015814"}, {"subsystem": "Transport", "name": "L-Glutamine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"gln-L_e": -1.0, "gln-L_c": 1.0}, "id": "TCE1122", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Lysophosphatidylcholine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"lpchol_e": -1.0}, "id": "EX04230", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "glycocholate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"gchola_c": 1.0, "gchola_e": -1.0}, "id": "TCE0559", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Cys-Gly transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"cgly_e": -1.0, "cgly_c": 1.0}, "id": "TCE0558", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Sulfate transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"so4_c": 1.0, "so4_e": -1.0}, "id": "TCE1127", "gene_reaction_rule": ""}, {"subsystem": "Pantothenate and CoA biosynthesis", "name": "(R)-4-Phosphopantothenate:L-cysteine ligase (CTP-dependent)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R04231", "ec-code": "6.3.2.5", "sbo": "SBO:0000176"}, "metabolites": {"cmp_c": 1.0, "ppi_c": 1.0, "4ppcys_c": 1.0, "ctp_c": -1.0, "h_c": 1.0, "4ppan_c": -1.0, "cys-L_c": -1.0}, "id": "RC04231", "gene_reaction_rule": "WBGene00022171"}, {"subsystem": "Pantothenate and CoA biosynthesis", "name": "(R)-4-Phosphopantothenate:L-cysteine ligase (ATP-dependent)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R04230", "ec-code": "6.3.2.5", "sbo": "SBO:0000176"}, "metabolites": {"atp_c": -1.0, "ppi_c": 1.0, "4ppcys_c": 1.0, "h_c": 1.0, "4ppan_c": -1.0, "cys-L_c": -1.0, "amp_c": 1.0}, "id": "RC04230", "gene_reaction_rule": "WBGene00022171"}, {"subsystem": "Miscellaneous", "name": "NADH:ferricytochrome-b5 oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00100", "ec-code": "1.6.2.2", "sbo": "SBO:0000176"}, "metabolites": {"focytb_c": 2.0, "nadh_c": -1.0, "h_c": -1.0, "nad_c": 1.0, "ficytb_c": -2.0}, "id": "RC00100", "gene_reaction_rule": "(WBGene00020267 or WBGene00020268)"}, {"subsystem": "Selenocompound metabolism", "name": "L-seryl-tRNA(Sec) kinase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R08223", "ec-code": "2.7.1.164", "sbo": "SBO:0000176"}, "metabolites": {"sertrna_sec_c": -1.0, "adp_c": 1.0, "atp_c": -1.0, "serptrna_c": 1.0}, "id": "RC08223", "gene_reaction_rule": "WBGene00013041"}, {"subsystem": "Selenocompound metabolism", "name": "selenophosphate:O-phospho-L-seryl-tRNA(Sec) selenium transferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R08224", "ec-code": "2.9.1.2", "sbo": "SBO:0000176"}, "metabolites": {"ppi_c": 1.0, "serptrna_c": -1.0, "h_c": 1.0, "sectrna_c": 1.0, "selnp_c": -1.0}, "id": "RC08224", "gene_reaction_rule": "WBGene00008379"}, {"subsystem": "Nicotinate and nicotinamide metabolism", "name": "NAD+ phosphohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00103", "ec-code": "3.6.1.9", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "nmn_c": 1.0, "amp_c": 1.0, "nad_c": -1.0, "h_c": 2.0}, "id": "RC00103", "gene_reaction_rule": "WBGene00007753 or WBGene00007755"}, {"subsystem": "Carnitine shuttle", "name": "Carnitine-acylcarnitine translocase (translocating pmtcrn)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"pmtcrn_c": -1.0, "pmtcrn_m": 1.0}, "id": "TCM5001", "gene_reaction_rule": "WBGene00000996 or WBGene00008320"}, {"subsystem": "Carnitine shuttle", "name": "Carnitine-acylcarnitine translocase (translocating ttdcrn)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"ttdcrn_c": -1.0, "ttdcrn_m": 1.0}, "id": "TCM5002", "gene_reaction_rule": "WBGene00000996 or WBGene00008320"}, {"subsystem": "Carnitine shuttle", "name": "Carnitine-acylcarnitine translocase (translocating ddcrn)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"ddcrn_c": -1.0, "ddcrn_m": 1.0}, "id": "TCM5003", "gene_reaction_rule": "WBGene00000996 or WBGene00008320"}, {"subsystem": "Transport", "name": "Isovaleryl-CoA transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"ivcoa_c": -1.0, "ivcoa_m": 1.0}, "id": "TCM5004", "gene_reaction_rule": ""}, {"subsystem": "Vitamin B12 metabolism", "name": "cobalamin transport into mitochondria", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"cbl1_c": -1.0, "cbl1_m": 1.0}, "id": "TCM5005", "gene_reaction_rule": ""}, {"subsystem": "Vitamin B12 metabolism", "name": "adenosylcobalamin transport into mitochondria", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"adocbl_c": -1.0, "adocbl_m": 1.0}, "id": "TCM5006", "gene_reaction_rule": ""}, {"subsystem": "Cyanoamino acid metabolism", "name": "beta cyanoalanine transport to and from mitochondrion", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"cyanala_c": 1.0, "cyanala_m": -1.0}, "id": "TCM5007", "gene_reaction_rule": ""}, {"subsystem": "Sulfur metabolism", "name": "sulfide transport to and from mitochondrion", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"h2s_m": -1.0, "h2s_c": 1.0}, "id": "TCM5008", "gene_reaction_rule": ""}, {"subsystem": "Carnitine shuttle", "name": "Carnitine-acylcarnitine translocase (translocating fa16p1n7crn)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"fa16p1n7crn_m": 1.0, "fa16p1n7crn_c": -1.0}, "id": "TCM5009", "gene_reaction_rule": "WBGene00000996 or WBGene00008320"}, {"subsystem": "One carbon pool by folate", "name": "5,6,7,8-tetrahydrofolate:NAD+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00936", "ec-code": "1.5.1.3", "sbo": "SBO:0000176"}, "metabolites": {"thf_c": 1.0, "nadh_c": -1.0, "dhf_c": -1.0, "nad_c": 1.0, "h_c": -1.0}, "id": "RC00936", "gene_reaction_rule": "WBGene00007974"}, {"subsystem": "Demand reactions", "name": "rhodoquinone demand", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"rq9_m": -1.0}, "id": "DMN0082", "gene_reaction_rule": ""}, {"subsystem": "N-Glycan biosynthesis", "name": "l2fn2m2masn demand", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"l2fn2m2masn_c": -1.0}, "id": "DMN0083", "gene_reaction_rule": ""}, {"subsystem": "Miscellaneous", "name": "cyclopropane fatty acid demand", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"coa_m": 1.0, "fa11c3coa_m": -1.0}, "id": "DMN0080", "gene_reaction_rule": ""}, {"subsystem": "Vitamin B12 metabolism", "name": "vitamin B12 demand (cbl1 form)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"cbl1_m": -1.0}, "id": "DMN0086", "gene_reaction_rule": ""}, {"subsystem": "Starch and sucrose metabolism", "name": "UDP-4-dehydro-6-deoxy-D-glucose demand", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"udpxyl_c": -1.0}, "id": "DMN0084", "gene_reaction_rule": ""}, {"subsystem": "Amino sugar and nucleotide sugar metabolism", "name": "UDP-D-xylose demand", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"udp4k6dg_c": -1.0}, "id": "DMN0085", "gene_reaction_rule": ""}, {"subsystem": "Starch and sucrose metabolism", "name": "maltose glucohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00028", "ec-code": "3.2.1.20", "sbo": "SBO:0000176"}, "metabolites": {"glc-D-A_c": 2.0, "h2o_c": -1.0, "malt_c": -1.0}, "id": "RC00028", "gene_reaction_rule": "WBGene00017071 or WBGene00019895"}, {"subsystem": "Exchange with the environment", "name": "Thymidine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"thymd_e": -1.0}, "id": "EX00214", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "\"3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoate\" transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"thcholstoic_m": -1.0, "thcholstoic_c": 1.0}, "id": "TCM1027", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Phosphatidylethanolamine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"pe_e": -1.0}, "id": "EX00350", "gene_reaction_rule": ""}, {"subsystem": "Fatty acid metabolism", "name": "long-chain-alcohol:NAD+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01998", "ec-code": "1.1.1.192", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "alkylR1oh_c": -1.0, "h_c": 3.0, "nad_c": -2.0, "nadh_c": 2.0, "Rtotal7_c": 1.0}, "id": "RC01998", "gene_reaction_rule": "WBGene00022200"}, {"subsystem": "Pyrimidine metabolism", "name": "(S)-dihydroorotate amidohydrolase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01993", "ec-code": "3.5.2.3", "sbo": "SBO:0000176"}, "metabolites": {"cbasp_c": 1.0, "h2o_c": -1.0, "dhor-S_c": -1.0, "h_c": 1.0}, "id": "RC01993", "gene_reaction_rule": "WBGene00004259"}, {"subsystem": "Maintenance", "name": "maintenance atp", "upper_bound": 1000.0, "lower_bound": 1.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "pi_c": 1.0, "adp_c": 1.0, "atp_c": -1.0, "h_c": 1.0}, "id": "RCC0005", "gene_reaction_rule": ""}, {"subsystem": "Glycolysis / Gluconeogenesis", "name": "ATP:pyruvate 2-O-phosphotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00200", "ec-code": "2.7.1.40", "sbo": "SBO:0000176"}, "metabolites": {"pep_c": -1.0, "pyr_c": 1.0, "h_c": -1.0, "adp_c": -1.0, "atp_c": 1.0}, "id": "RC00200", "gene_reaction_rule": "WBGene00009126 or WBGene00014001"}, {"subsystem": "Glycerolipid metabolism", "name": "D-Glyceraldehyde:NAD+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01752", "ec-code": "1.2.1.3", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "glyald_c": -1.0, "glyc-R_c": 1.0, "h_c": 2.0, "nad_c": -1.0, "nadh_c": 1.0}, "id": "RC01752", "gene_reaction_rule": "(WBGene00000108 or WBGene00000110) or (WBGene00000117 or WBGene00000118)"}, {"subsystem": "Fatty acid metabolism", "name": "(S)-3-Hydroxybutanoyl-CoA:NAD+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01975", "ec-code": "1.1.1.35", "sbo": "SBO:0000176"}, "metabolites": {"aacoa_c": -1.0, "3hbcoa_c": 1.0, "nadh_c": -1.0, "h_c": -1.0, "nad_c": 1.0}, "id": "RC01975", "gene_reaction_rule": "WBGene00010035 or WBGene00001157 or WBGene00001158 or WBGene00019978"}, {"subsystem": "Fatty acid metabolism", "name": "(S)-3-Hydroxybutanoyl-CoA hydro-lyase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R03026", "ec-code": "4.2.1.17", "sbo": "SBO:0000176"}, "metabolites": {"b2coa_m": 1.0, "h2o_m": 1.0, "3hbcoa_m": -1.0}, "id": "RM03026", "gene_reaction_rule": "(WBGene00001155 or WBGene00001156) or (WBGene00020347 or WBGene00001150) or WBGene00001152"}, {"subsystem": "Pentose and glucuronate interconversions", "name": "L-Arabitol:NADP+ 1-oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01759", "ec-code": "1.1.1.21", "sbo": "SBO:0000176"}, "metabolites": {"abt_c": 1.0, "nadp_c": 1.0, "nadph_c": -1.0, "arab-L_c": -1.0, "h_c": -1.0}, "id": "RC01759", "gene_reaction_rule": "WBGene00012722"}, {"subsystem": "Pentose and glucuronate interconversions", "name": "L-Arabitol:NAD+ 1-oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01758", "ec-code": "1.1.1.21", "sbo": "SBO:0000176"}, "metabolites": {"abt_c": 1.0, "nadh_c": -1.0, "arab-L_c": -1.0, "nad_c": 1.0, "h_c": -1.0}, "id": "RC01758", "gene_reaction_rule": "WBGene00012722"}, {"subsystem": "Synthesis and degradation of ketone bodies", "name": "acetyl-CoA:acetoacetyl-CoA C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01978", "ec-code": "2.3.3.10", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "aacoa_c": -1.0, "hmgcoa_c": 1.0, "coa_c": 1.0, "h_c": 1.0, "accoa_c": -1.0}, "id": "RC01978", "gene_reaction_rule": "WBGene00017769"}, {"subsystem": "Fatty acid metabolism", "name": "fatty-acid--CoA ligase (Rtotal4)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00390", "ec-code": "6.2.1.3", "sbo": "SBO:0000176"}, "metabolites": {"atp_c": -1.0, "ppi_c": 1.0, "coa_c": -1.0, "amp_c": 1.0, "Rtotal4coa_c": 1.0, "Rtotal4_c": -1.0}, "id": "RCC0151", "gene_reaction_rule": "WBGene00009221 or WBGene00020343 or WBGene00018152 or WBGene00013575 or WBGene00022037 or WBGene00019920 or WBGene00016716 or WBGene00011173"}, {"subsystem": "Fatty acid metabolism", "name": "fatty-acid--CoA ligase (Rtotal2)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00390", "ec-code": "6.2.1.3", "sbo": "SBO:0000176"}, "metabolites": {"Rtotal2coa_c": 1.0, "atp_c": -1.0, "Rtotal2_c": -1.0, "ppi_c": 1.0, "coa_c": -1.0, "amp_c": 1.0}, "id": "RCC0150", "gene_reaction_rule": "WBGene00009221 or WBGene00020343 or WBGene00018152 or WBGene00013575 or WBGene00022037 or WBGene00019920 or WBGene00016716 or WBGene00011173"}, {"subsystem": "Propanoate metabolism", "name": "Propionyl-CoA:carnitine O-propionyltransferase II", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "2.3.1.7", "sbo": "SBO:0000176"}, "metabolites": {"crn_c": -1.0, "pcrn_c": 1.0, "coa_c": 1.0, "ppcoa_c": -1.0}, "id": "RCC0153", "gene_reaction_rule": "WBGene00007175"}, {"subsystem": "Fatty acid metabolism", "name": "fatty-acid--CoA ligase (Rtotal5)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00390", "ec-code": "6.2.1.3", "sbo": "SBO:0000176"}, "metabolites": {"Rtotal5_c": -1.0, "atp_c": -1.0, "ppi_c": 1.0, "coa_c": -1.0, "amp_c": 1.0, "Rtotal5coa_c": 1.0}, "id": "RCC0152", "gene_reaction_rule": "WBGene00009221 or WBGene00020343 or WBGene00018152 or WBGene00013575 or WBGene00022037 or WBGene00019920 or WBGene00016716 or WBGene00011173"}, {"subsystem": "Folate biosynthesis", "name": "sepiapterin reductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R04285", "R01813"], "ec-code": "1.1.1.153", "sbo": "SBO:0000176"}, "metabolites": {"thbpt_c": 1.0, "nadp_c": 2.0, "nadph_c": -2.0, "h_c": -2.0, "6pthp_c": -1.0}, "id": "RCC0157", "gene_reaction_rule": ""}, {"subsystem": "Miscellaneous", "name": "tyramine beta-monooxygenase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "1.14.17.-", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "h2o_c": 1.0, "octpmn_c": 1.0, "dhdascb_c": 1.0, "tym_c": -1.0, "ascb-L_c": -1.0}, "id": "RCC0156", "gene_reaction_rule": "WBGene00006541"}, {"subsystem": "Carnitine biosynthesis", "name": "artificial transformation of peptide to peptidyl-lysine", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"lys-L_c": -1.0, "peplys_c": 1.0, "pepX_c": -1.0, "h2o_c": 1.0}, "id": "RCC0159", "gene_reaction_rule": ""}, {"subsystem": "Glutathione metabolism", "name": "glutathione:NADP+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00115", "ec-code": "1.8.1.7", "sbo": "SBO:0000176"}, "metabolites": {"gthrd_c": 2.0, "nadp_c": 1.0, "nadph_c": -1.0, "h_c": -1.0, "gthox_c": -1.0}, "id": "RC00115", "gene_reaction_rule": "WBGene00008117"}, {"subsystem": "Peroxisomal fatty acid beta oxidation", "name": "peroxisomal multifunctional enzyme type 2 (acting on hdd2coa)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R04737", "R04738"], "ec-code": ["4.2.1.17", "1.1.1.211", "1.1.1.35"], "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "3ohdcoa_c": 1.0, "h_c": 1.0, "nad_c": -1.0, "nadh_c": 1.0, "hdd2coa_c": -1.0}, "id": "RCC0083", "gene_reaction_rule": "WBGene00000991 or WBGene00017123"}, {"subsystem": "Glycerolipid metabolism", "name": "ATP:1,2-diacylglycerol 3-phosphotransferase (acting on neutral lipid components)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02240", "ec-code": "2.7.1.107", "sbo": "SBO:0000176"}, "metabolites": {"h_c": 1.0, "pa_tag_c": 1.0, "dag_tag_c": -1.0, "atp_c": -1.0, "adp_c": 1.0}, "id": "RCC0082", "gene_reaction_rule": "WBGene00000958 or WBGene00000959 or WBGene00000960 or WBGene00006483 or WBGene00019428"}, {"subsystem": "Glycerolipid metabolism", "name": "1,2-diacyl-sn-glycerol 3-phosphate phosphohydrolase (acting on TAG)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02239", "ec-code": "3.1.3.4", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "pi_c": 1.0, "pa_tag_c": -1.0, "dag_tag_c": 1.0}, "id": "RCC0081", "gene_reaction_rule": "(WBGene00008749 or WBGene00018756 or WBGene00020895) or WBGene00010425"}, {"subsystem": "Glycerolipid metabolism", "name": "acyl-CoA:1-acyl-sn-glycerol-3-phosphate 2-O-acyltransferase (Rtotal5 group)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02241", "ec-code": "2.3.1.51", "sbo": "SBO:0000176"}, "metabolites": {"Rtotal5coa_c": -1.0, "coa_c": 1.0, "pa_tag_c": 1.0, "alpa_tag_c": -1.0}, "id": "RCC0080", "gene_reaction_rule": "((WBGene00020264 or WBGene00022646 or WBGene00044631) or (WBGene00010339 or WBGene00011543) or (WBGene00016934 or WBGene00007446)) or WBGene00017888"}, {"subsystem": "Carnitine shuttle", "name": "Octanoyl-CoA:L-carnitine O-octanoyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03779", "ec-code": "2.3.1.137", "sbo": "SBO:0000176"}, "metabolites": {"crn_c": -1.0, "coa_c": 1.0, "occrn_c": 1.0, "occoa_c": -1.0}, "id": "RCC0087", "gene_reaction_rule": "WBGene00009622 or WBGene00011850"}, {"subsystem": "Peroxisomal fatty acid beta oxidation", "name": "peroxisomal multifunctional enzyme type 2 (acting on dc2coa)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R04743", "R04744"], "ec-code": ["4.2.1.17", "1.1.1.211", "1.1.1.35"], "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "dc2coa_c": -1.0, "3odcoa_c": 1.0, "h_c": 1.0, "nad_c": -1.0, "nadh_c": 1.0}, "id": "RCC0086", "gene_reaction_rule": "WBGene00000991 or WBGene00017123"}, {"subsystem": "Peroxisomal fatty acid beta oxidation", "name": "peroxisomal multifunctional enzyme type 2 (acting on dd2coa)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R04741", "R04170"], "ec-code": ["4.2.1.17", "1.1.1.211", "1.1.1.35"], "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "dd2coa_c": -1.0, "h_c": 1.0, "nad_c": -1.0, "3oddcoa_c": 1.0, "nadh_c": 1.0}, "id": "RCC0085", "gene_reaction_rule": "WBGene00000991 or WBGene00017123"}, {"subsystem": "Peroxisomal fatty acid beta oxidation", "name": "peroxisomal multifunctional enzyme type 2 (acting on td2coa)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R04739", "R04740"], "ec-code": ["4.2.1.17", "1.1.1.211", "1.1.1.35"], "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "3otdcoa_c": 1.0, "h_c": 1.0, "nad_c": -1.0, "td2coa_c": -1.0, "nadh_c": 1.0}, "id": "RCC0084", "gene_reaction_rule": "WBGene00000991 or WBGene00017123"}, {"subsystem": "Peroxisomal fatty acid beta oxidation", "name": "Beta oxidation of oleic acid (peroxisomal)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R00388", "R02685", "R01778", "R00391"], "ec-code": ["1.3.3.6", "4.2.1.17", "1.1.1.211", "1.1.1.35", "2.3.1.16"], "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "h2o_c": -1.0, "odecoa_c": -1.0, "nad_c": -1.0, "fa16p1n7coa_c": 1.0, "h2o2_c": 1.0, "coa_c": -1.0, "h_c": 1.0, "accoa_c": 1.0, "nadh_c": 1.0}, "id": "RCC0089", "gene_reaction_rule": "(WBGene00008167 or WBGene00008564 or WBGene00008565 or WBGene00008566 or WBGene00008567 or WBGene00019060 or WBGene00010336) and (WBGene00000991 or WBGene00017123) and WBGene00013284"}, {"subsystem": "Peroxisomal fatty acid beta oxidation", "name": "Beta oxidation of palmitoleic acid (peroxisomal)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R00388", "R01778", "R00391"], "ec-code": ["1.3.3.6", "5.3.3.8", "4.2.1.17", "1.1.1.211", "1.1.1.35", "2.3.1.16"], "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -3.0, "h2o_c": -4.0, "nad_c": -4.0, "h2o2_c": 3.0, "coa_c": -4.0, "h_c": 4.0, "fa16p1n7coa_c": -1.0, "nadh_c": 4.0, "occoa_c": 1.0, "accoa_c": 4.0}, "id": "RCC0088", "gene_reaction_rule": "(WBGene00008167 or WBGene00008564 or WBGene00008565 or WBGene00008566 or WBGene00008567 or WBGene00019060 or WBGene00010336) and WBGene00019022 and (WBGene00000991 or WBGene00017123) and WBGene00013284"}, {"subsystem": "Propanoate metabolism", "name": "3-Hydroxypropionyl-CoA hydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03158", "ec-code": "3.1.2.4", "sbo": "SBO:0000176"}, "metabolites": {"coa_m": 1.0, "h_m": 1.0, "h2o_m": -1.0, "3hpcoa_m": -1.0, "3hpp_m": 1.0}, "id": "RM03158", "gene_reaction_rule": "WBGene00017301"}, {"subsystem": "Phenylalanine metabolism", "name": "Phenylpyruvate:oxygen oxidoreductase (hydroxylating,decarboxylating)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01372", "ec-code": "1.13.11.27", "sbo": "SBO:0000176"}, "metabolites": {"phpyr_c": -1.0, "o2_c": -1.0, "2hyoxplac_c": 1.0, "co2_c": 1.0}, "id": "RC01372", "gene_reaction_rule": "WBGene00016294 or WBGene00001993"}, {"subsystem": "Phenylalanine metabolism (indirect)", "name": "L-Glutamine:phenylpyruvate aminotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01375", "ec-code": "2.6.1.64", "sbo": "SBO:0000176"}, "metabolites": {"phpyr_c": -1.0, "akgm_c": 1.0, "phe-L_c": 1.0, "gln-L_c": -1.0}, "id": "RC01375", "gene_reaction_rule": "WBGene00009232"}, {"subsystem": "Phenylalanine metabolism", "name": "Phenylpyruvate keto-enol-isomerase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01378", "ec-code": "5.3.2.1", "sbo": "SBO:0000176"}, "metabolites": {"phpyr_c": -1.0, "enphpyr_c": 1.0}, "id": "RC01378", "gene_reaction_rule": "WBGene00003234"}, {"subsystem": "Exchange with the environment", "name": "4-Aminobutanoate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"4abut_e": -1.0}, "id": "EX00334", "gene_reaction_rule": ""}, {"subsystem": "Glycine, serine and threonine metabolism", "name": "L-threonine acetaldehyde-lyase (glycine-forming)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00751", "ec-code": "4.1.2.5", "sbo": "SBO:0000176"}, "metabolites": {"thr-L_c": -1.0, "acald_c": 1.0, "gly_c": 1.0}, "id": "RC00751", "gene_reaction_rule": "WBGene00011291"}, {"subsystem": "Exchange with the environment", "name": "5-Methyltetrahydrofolate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"5mthf_e": -1.0}, "id": "EX00440", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Phosphatidylserine (bacteria) exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"ps_BAC_e": -1.0}, "id": "EXC0060", "gene_reaction_rule": ""}, {"subsystem": "Glycolysis / Gluconeogenesis", "name": "ethanol:NAD+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00754", "ec-code": "1.1.1.1", "sbo": "SBO:0000176"}, "metabolites": {"acald_c": 1.0, "nadh_c": 1.0, "nad_c": -1.0, "etoh_c": -1.0, "h_c": 1.0}, "id": "RC00754", "gene_reaction_rule": "WBGene00019240 or (WBGene00017060 or WBGene00010790 or WBGene00010791)"}, {"subsystem": "Exchange with the environment", "name": "glycogen exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"glycogen_BAC_e": -1.0}, "id": "EXC0065", "gene_reaction_rule": ""}, {"subsystem": "Primary bile acid biosynthesis", "name": "7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R04826", "ec-code": "1.14.13.95", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "h2o_c": 1.0, "nadp_c": 1.0, "nadph_c": -1.0, "xol7aone_c": -1.0, "h_c": -1.0, "xoldiolone_c": 1.0}, "id": "RC04826", "gene_reaction_rule": ""}, {"subsystem": "Primary bile acid biosynthesis", "name": "3alpha-hydroxysteroid dehydrogenase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R04824", "ec-code": "1.1.1.50", "sbo": "SBO:0000176"}, "metabolites": {"xoltriol_c": 1.0, "nad_c": 1.0, "nadh_c": -1.0, "h_c": -1.0, "xoldioloneh_c": -1.0}, "id": "RC04824", "gene_reaction_rule": "WBGene00012722 or WBGene00020369 or WBGene00015565 or WBGene00013896 or WBGene00012723 or WBGene00009981 or WBGene00009980"}, {"subsystem": "Exchange with the environment", "name": "R total 2 position exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"Rtotal2_e": -1.0}, "id": "EXC0001", "gene_reaction_rule": ""}, {"subsystem": "Primary bile acid biosynthesis", "name": "3-oxo-Delta4-steroid 5beta-reductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R04823", "ec-code": "1.3.1.3", "sbo": "SBO:0000176"}, "metabolites": {"xoldiolone_c": -1.0, "nadp_c": 1.0, "nadph_c": -1.0, "h_c": -1.0, "xoldioloneh_c": 1.0}, "id": "RC04823", "gene_reaction_rule": "WBGene00012722 or WBGene00020369 or WBGene00015565 or WBGene00013896 or WBGene00012723 or WBGene00009981 or WBGene00009980"}, {"subsystem": "Nicotinate and nicotinamide metabolism", "name": "N-Ribosylnicotinamide:orthophosphate ribosyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R02294", "ec-code": "2.4.2.1", "sbo": "SBO:0000176"}, "metabolites": {"rnam_c": -1.0, "pi_c": -1.0, "h_c": 1.0, "r1p_c": 1.0, "ncam_c": 1.0}, "id": "RC02294", "gene_reaction_rule": "WBGene00019298"}, {"subsystem": "Exchange with the environment", "name": "pyridoxamine exchange/defecation", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"pydam_e": -1.0}, "id": "EX00534", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Testosterone exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"tststerone_e": -1.0}, "id": "EX00535", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "L-Arabinitol exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"abt_e": -1.0}, "id": "EX00532", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "L-Lysine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"lys-L_c": -1.0, "lys-L_m": 1.0}, "id": "TCM0089", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "dTDP and ADP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"adp_m": -1.0, "dtdp_m": 1.0, "dtdp_c": -1.0, "adp_c": 1.0}, "id": "TCM0088", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "dUDP and ADP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"adp_m": -1.0, "dudp_m": 1.0, "dudp_c": -1.0, "adp_c": 1.0}, "id": "TCM0087", "gene_reaction_rule": ""}, {"subsystem": "Pyrimidine metabolism", "name": "thymidine:phosphate deoxy-alpha-D-ribosyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01570 ", "ec-code": "2.4.2.4", "sbo": "SBO:0000176"}, "metabolites": {"2dr1p_c": 1.0, "pi_c": -1.0, "thym_c": 1.0, "thymd_c": -1.0}, "id": "RC01570", "gene_reaction_rule": "WBGene00022817"}, {"subsystem": "Transport", "name": "dGDP and dCDP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dcdp_m": 1.0, "dgdp_c": 1.0, "dgdp_m": -1.0, "dcdp_c": -1.0}, "id": "TCM0083", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "dTDP and dUTP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dtdp_m": -1.0, "dutp_m": 1.0, "dtdp_c": 1.0, "dutp_c": -1.0}, "id": "TCM0082", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "dTDP and dADP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dadp_c": -1.0, "dtdp_m": -1.0, "dtdp_c": 1.0, "dadp_m": 1.0}, "id": "TCM0081", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "dTTP and ATP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"atp_m": -1.0, "dttp_m": 1.0, "dttp_c": -1.0, "atp_c": 1.0}, "id": "TCM0080", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "AMP excretion", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"amp_e": -1.0}, "id": "EX00020", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "S-Adenosyl-L-homocysteine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"ahcys_e": -1.0}, "id": "EX00021", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Pyruvate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"pyr_e": -1.0}, "id": "EX00022", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "L-Glutamate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"glu-L_e": -1.0}, "id": "EX00025", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "2-Oxoglutarate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"akg_e": -1.0}, "id": "EX00026", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Hydrogen peroxide exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"h2o2_e": -1.0}, "id": "EX00027", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "ADPribose transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"adprib_e": -1.0, "adprib_c": 1.0}, "id": "TCE0739", "gene_reaction_rule": ""}, {"subsystem": "Inositol phosphate metabolism", "name": "phosphatidylinositol 3,5-bisphosphate 5-phosphatase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R12124", "ec-code": "3.1.3.-", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "pi_c": 1.0, "pail35p_c": -1.0, "pail3p_c": 1.0}, "id": "RC12124", "gene_reaction_rule": "WBGene00007912"}, {"subsystem": "Transport", "name": "Methanol transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"meoh_e": -1.0, "meoh_c": 1.0}, "id": "TCE0597", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Deoxyadenosine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dad-2_c": 1.0, "dad-2_e": -1.0}, "id": "TCE0732", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Sucrose transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"sucr_c": 1.0, "sucr_e": -1.0}, "id": "TCE1156", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "dTTP transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dttp_e": -1.0, "dttp_c": 1.0}, "id": "TCE1157", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Citrate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"cit_e": -1.0, "cit_c": 1.0}, "id": "TCE1154", "gene_reaction_rule": ""}, {"subsystem": "Cysteine and methionine metabolism", "name": "S-methyl-5-thioadenosine:phosphate S-methyl-5-thio-alpha-D-ribosyl-transferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01402", "ec-code": "2.4.2.28", "sbo": "SBO:0000176"}, "metabolites": {"ade_c": 1.0, "5mta_c": -1.0, "pi_c": -1.0, "5mdr1p_c": 1.0}, "id": "RC01402", "gene_reaction_rule": "WBGene00015064"}, {"subsystem": "Transport", "name": "Peptide transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"pepd_c": 1.0, "pepd_e": -1.0}, "id": "TCE1150", "gene_reaction_rule": ""}, {"subsystem": "Purine metabolism", "name": "ATP:AMP phosphotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00127", "ec-code": "2.7.4.3", "sbo": "SBO:0000176"}, "metabolites": {"atp_m": -1.0, "adp_m": 2.0, "amp_m": -1.0}, "id": "RM00127", "gene_reaction_rule": " WBGene00014058 or WBGene00002879"}, {"subsystem": "Transport", "name": "Succinate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"succ_c": 1.0, "succ_e": -1.0}, "id": "TCE1159", "gene_reaction_rule": ""}, {"subsystem": "Sphingolipid metabolism", "name": "ceramide:phosphatidylcholine cholinephosphotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R08969", "ec-code": "2.7.8.27", "sbo": "SBO:0000176"}, "metabolites": {"crm_ce_c": -1.0, "dag_pl_c": 1.0, "sphmyln_ce_c": 1.0, "pchol_c": -1.0}, "id": "RC08969", "gene_reaction_rule": "WBGene00021075 or WBGene00004892 or WBGene00004893 or WBGene00004894"}, {"subsystem": "Exchange with the environment", "name": "Phosphatidylcholine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"pchol_e": -1.0}, "id": "EX00157", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "L-Asparagine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"asn-L_e": -1.0}, "id": "EX00152", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Nicotinamide exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"ncam_e": -1.0}, "id": "EX00153", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Citrate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"cit_e": -1.0}, "id": "EX00158", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "D-Mannose exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"man_e": -1.0}, "id": "EX00159", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Bicarbonate and Cholate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"cholate_e": -1.0, "cholate_c": 1.0, "hco3_e": 1.0, "hco3_c": -1.0}, "id": "TCE0785", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "2-Hydroxyphenylacetate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"2hyoxplac_e": -1.0}, "id": "EX05852", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Bicarbonate and Bilirubin transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"bilirub_e": -1.0, "hco3_c": -1.0, "bilirub_c": 1.0, "hco3_e": 1.0}, "id": "TCE0536", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "3-4-Dihydroxyphenylacetate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"34dhpha_e": -1.0}, "id": "EX01161", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "5-Hydroxy-L-tryptophan transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"h2o_c": -2.0, "adp_c": 2.0, "atp_c": -2.0, "5htrp_e": 3.0, "h_c": 2.0, "5htrp_c": -3.0, "pi_c": 2.0}, "id": "TCE0600", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "\"3',5'-Cyclic GMP\" transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"h2o_c": -1.0, "atp_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "35cgmp_e": 1.0, "pi_c": 1.0, "35cgmp_c": -1.0}, "id": "TCE0603", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Bicarbonate and Chloride transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"cl_e": 1.0, "hco3_e": -1.0, "hco3_c": 1.0, "cl_c": -1.0}, "id": "TCE0602", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Inosine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"ins_e": -1.0, "ins_c": 1.0}, "id": "TCE0605", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "dCDP and dCTP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dcdp_m": -1.0, "dcdp_c": 1.0, "dctp_m": 1.0, "dctp_c": -1.0}, "id": "TCM0184", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Choline transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"chol_c": 1.0, "chol_e": -1.0}, "id": "TCE0757", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Adenosine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"adn_m": 1.0, "adn_c": -1.0}, "id": "TCM0185", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Glyoxylate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"glx_m": 1.0, "glx_c": -1.0}, "id": "TCM0183", "gene_reaction_rule": ""}, {"subsystem": "Glycerophospholipid metabolism", "name": "Phosphatidylethanolamine phosphatidohydrolase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R02051", "ec-code": "3.1.4.4", "sbo": "SBO:0000176"}, "metabolites": {"pa_pl_c": 1.0, "h2o_c": -1.0, "h_c": 1.0, "etha_c": 1.0, "pe_c": -1.0}, "id": "RC02051", "gene_reaction_rule": "WBGene00004040 or (WBGene00017316 or WBGene00020256 or WBGene00013080)"}, {"subsystem": "Glycerophospholipid metabolism", "name": "Phosphatidylethanolamine 2-acylhydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02053", "ec-code": "3.1.1.4", "sbo": "SBO:0000176"}, "metabolites": {"h_c": 1.0, "Rtotal2_c": 1.0, "h2o_c": -1.0, "acg3pe_c": 1.0, "pe_c": -1.0}, "id": "RC02053", "gene_reaction_rule": "WBGene00019747 or WBGene00009801 or WBGene00012319 or WBGene00017026 or WBGene00019229 or WBGene00022233 or WBGene00011423 or WBGene00007419 or WBGene00044468"}, {"subsystem": "Fatty acid elongation", "name": "very-long-chain 3-oxoacyl-CoA reductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R07759", "ec-code": "1.1.1.330", "sbo": "SBO:0000176"}, "metabolites": {"3hodcoa_c": 1.0, "3oodcoa_c": -1.0, "nadp_c": 1.0, "nadph_c": -1.0, "h_c": -1.0}, "id": "RC07759", "gene_reaction_rule": "WBGene00002891"}, {"subsystem": "Fatty acid elongation", "name": "very-long-chain 3-oxoacyl-CoA synthase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R07758", "ec-code": "2.3.1.199", "sbo": "SBO:0000176"}, "metabolites": {"malcoa_c": -1.0, "pmtcoa_c": -1.0, "3oodcoa_c": 1.0, "coa_c": 1.0, "h_c": -1.0, "co2_c": 1.0}, "id": "RC07758", "gene_reaction_rule": "WBGene00001239"}, {"subsystem": "Glycerophospholipid metabolism", "name": "CDPethanolamine:1,2-diacylglycerol ethanolaminephosphotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R02057", "ec-code": "2.7.8.1", "sbo": "SBO:0000176"}, "metabolites": {"cdpea_c": -1.0, "dag_pl_c": -1.0, "pe_c": 1.0, "h_c": 1.0, "cmp_c": 1.0}, "id": "RC02057", "gene_reaction_rule": "WBGene00018797 or WBGene00013024"}, {"subsystem": "One carbon pool by folate", "name": "Formate:tetrahydrofolate ligase (ADP-forming)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00943", "ec-code": "6.3.4.3", "sbo": "SBO:0000176"}, "metabolites": {"atp_m": -1.0, "adp_m": 1.0, "10fthf_m": 1.0, "pi_m": 1.0, "for_m": -1.0, "thf_m": -1.0}, "id": "RM00943", "gene_reaction_rule": "WBGene00019492"}, {"subsystem": "Amino sugar and nucleotide sugar metabolism", "name": "acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02058", "ec-code": "2.3.1.4", "sbo": "SBO:0000176"}, "metabolites": {"coa_c": 1.0, "gam6p_c": -1.0, "acgam6p_c": 1.0, "h_c": 1.0, "accoa_c": -1.0}, "id": "RC02058", "gene_reaction_rule": "WBGene00001646 or WBGene00001647"}, {"subsystem": "Transport", "name": "Fumarate and Sulfate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"so4_c": 1.0, "fum_c": -1.0, "fum_m": 1.0, "so4_m": -1.0}, "id": "TCM0181", "gene_reaction_rule": ""}, {"subsystem": "Glycine, serine and threonine metabolism", "name": "5,10-Methylenetetrahydrofolate:glycine hydroxymethyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00945", "ec-code": "2.1.2.1", "sbo": "SBO:0000176"}, "metabolites": {"mlthf_m": 1.0, "gly_m": 1.0, "thf_m": -1.0, "h2o_m": 1.0, "ser-L_m": -1.0}, "id": "RM00945", "gene_reaction_rule": "WBGene00003214"}, {"subsystem": "Transport", "name": "Glycine betaine and Sodium transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"glyb_e": -1.0, "na1_c": 2.0, "glyb_c": 1.0, "na1_e": -2.0}, "id": "TCE0752", "gene_reaction_rule": ""}, {"subsystem": "Valine, leucine and isoleucine degradation", "name": "L-Leucine:2-oxoglutarate aminotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01090", "ec-code": "2.6.1.42", "sbo": "SBO:0000176"}, "metabolites": {"glu-L_m": 1.0, "4mop_m": 1.0, "leu-L_m": -1.0, "akg_m": -1.0}, "id": "RM01090", "gene_reaction_rule": "WBGene00001149 or WBGene00012855"}, {"subsystem": "Transport", "name": "propionate transport into and out of cytosol", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"ppa_c": 1.0, "ppa_e": -1.0}, "id": "TCE5035", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Uracil transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"ura_c": 1.0, "ura_e": -1.0}, "id": "TCE0514", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "hydroxide transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"oh1_c": -1.0, "oh1_e": 1.0}, "id": "TCE5036", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "transport of N-acetyl ornithine", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"acorn_e": -1.0, "acorn_c": 1.0}, "id": "TCE5031", "gene_reaction_rule": ""}, {"subsystem": "N-Glycan biosynthesis", "name": "Dolichyl-diphosphate:polyphosphate phosphotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R02186", "ec-code": "2.7.4.20", "sbo": "SBO:0000176"}, "metabolites": {"doldp_c": -1.0, "ppi_c": 1.0, "pi_c": -1.0, "dolp_c": 1.0}, "id": "RC02186", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Phosphatidylethanolamine (bacteria) transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"h2o_c": -1.0, "atp_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "pe_BAC_e": -1.0, "pi_c": 1.0, "pe_BAC_c": 1.0}, "id": "TCE0513", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "\"6,7-Dihydrobiopterin\" exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"dhbpt_e": -1.0}, "id": "EX00268", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "cellobiose transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"clb_e": 1.0, "clb_c": -1.0}, "id": "TCE5038", "gene_reaction_rule": ""}, {"subsystem": "Ether lipid metabolism", "name": "1-Alkyl-2-acetyl-sn-glycero-3-phosphate phosphohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03454", "ec-code": "3.1.3.59", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "acakgp_c": -1.0, "acakg_c": 1.0, "pi_c": 1.0}, "id": "RC03454", "gene_reaction_rule": ""}, {"subsystem": "Ether lipid metabolism", "name": "Acetyl-CoA:1-alkyl-sn-glycero-3-phosphate 2-O-acetyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03455", "ec-code": "2.3.1.105", "sbo": "SBO:0000176"}, "metabolites": {"acakgp_c": 1.0, "coa_c": 1.0, "akgp_c": -1.0, "accoa_c": -1.0}, "id": "RC03455", "gene_reaction_rule": ""}, {"subsystem": "Fatty acid elongation", "name": "(S)-3-Hydroxyhexadecanoyl-CoA hydro-lyase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R04738", "ec-code": "4.2.1.17", "sbo": "SBO:0000176"}, "metabolites": {"hdd2coa_m": 1.0, "3hhdcoa_m": -1.0, "h2o_m": 1.0}, "id": "RM04738", "gene_reaction_rule": "(WBGene00001155 or WBGene00001156) or (WBGene00020347 or WBGene00001150) or WBGene00001152"}, {"subsystem": "Fatty acid elongation", "name": "(S)-3-Hydroxytetradecanoyl-CoA:NAD+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R04739", "ec-code": ["1.1.1.211", "1.1.1.35"], "sbo": "SBO:0000176"}, "metabolites": {"nad_m": 1.0, "h_m": -1.0, "3otdcoa_m": -1.0, "nadh_m": -1.0, "3htdcoa_m": 1.0}, "id": "RM04739", "gene_reaction_rule": "(WBGene00007129 or WBGene00010035 or WBGene00001157 or WBGene00001158 or WBGene00019978) or (WBGene00020347 or WBGene00001150)"}, {"subsystem": "Steroid hormone biosynthesis", "name": "UDP-glucuronate-androsterone glucuronyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02478", "ec-code": "2.4.1.17", "sbo": "SBO:0000176"}, "metabolites": {"andrstrnglc_c": 1.0, "andrstrn_c": -1.0, "udp_c": 1.0, "udpglcur_c": -1.0}, "id": "RC02478", "gene_reaction_rule": "WBGene00015371 or WBGene00016959 or WBGene00017334 or WBGene00018789 or WBGene00019235 or WBGene00019379 or WBGene00007072 or WBGene00020594 or WBGene00020593 or WBGene00020592 or WBGene00019232 or WBGene00019233 or WBGene00008097 or WBGene00013901 or WBGene00007422 or WBGene00013900 or WBGene00019515 or WBGene00007073 or WBGene00019516 or WBGene00007885 or WBGene00007455 or WBGene00007650 or WBGene00016762 or WBGene00015692 or WBGene00015695 or WBGene00015694 or WBGene00021709 or WBGene00013903 or WBGene00011340 or WBGene00021464 or WBGene00018543 or WBGene00007946 or WBGene00009255 or WBGene00044286 or WBGene00017315 or WBGene00017332 or WBGene00017333 or WBGene00017329 or WBGene00013905 or WBGene00017331 or WBGene00017336 or WBGene00017959 or WBGene00008485 or WBGene00008486 or WBGene00021372 or WBGene00015141 or WBGene00011006 or WBGene00015965 or WBGene00007070 or WBGene00013906 or WBGene00011564 or WBGene00015369 or WBGene00018931 or WBGene00020182 or WBGene00012013 or WBGene00011452 or WBGene00011453 or WBGene00009450 or WBGene00011238 or WBGene00013904 or WBGene00007402 or WBGene00018206 or WBGene00010904 or WBGene00015449 or WBGene00015577 or WBGene00008583 or WBGene00015739 or WBGene00019234 or WBGene00020587"}, {"subsystem": "Fatty acid elongation", "name": "(S)-3-Hydroxyhexadecanoyl-CoA:NAD+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R04737", "ec-code": ["1.1.1.35", "1.1.1.211"], "sbo": "SBO:0000176"}, "metabolites": {"3ohdcoa_m": -1.0, "3hhdcoa_m": 1.0, "h_m": -1.0, "nadh_m": -1.0, "nad_m": 1.0}, "id": "RM04737", "gene_reaction_rule": "(WBGene00007129 or WBGene00010035 or WBGene00001157) or (WBGene00020347 or WBGene00001150)"}, {"subsystem": "Ubiquinone and other terpenoid-quinone biosynthesis", "name": "nonaprenyl-4-hydroxybenzoate transferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R07273", "ec-code": "2.5.1.39", "sbo": "SBO:0000176"}, "metabolites": {"ppi_m": 1.0, "nonadp_m": -1.0, "3nphb_m": 1.0, "4hbz_m": -1.0}, "id": "RM07273", "gene_reaction_rule": "WBGene00000762"}, {"subsystem": "Methane metabolism", "name": "trimethylamine monooxygenase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R05623", "ec-code": "1.14.13.8", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "h2o_c": 1.0, "nadp_c": 1.0, "nadph_c": -1.0, "tmao_c": 1.0, "tma_c": -1.0}, "id": "RC05623", "gene_reaction_rule": "WBGene00001476 or WBGene00001477 or WBGene00001478 or WBGene00001479 or WBGene00001480"}, {"subsystem": "Transport", "name": "sphingosylphosphorylcholine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"spc_ce_e": 1.0, "spc_ce_c": -1.0}, "id": "TCE5101", "gene_reaction_rule": ""}, {"subsystem": "Arachidonic acid metabolism", "name": "(7E,9E,11Z,14Z)-(5S,6S)-5,6-Epoxyicosa-7,9,11,14-tetraenoate hydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03057", "ec-code": "3.3.2.6", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "leuktrA4_c": -1.0, "leuktrB4_c": 1.0}, "id": "RC03057", "gene_reaction_rule": "WBGene00016589 or WBGene00022610"}, {"subsystem": "Transport", "name": "Sphingosine 1-phosphate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"sphs1p_ce_c": -1.0, "sphs1p_ce_e": 1.0}, "id": "TCE5103", "gene_reaction_rule": ""}, {"subsystem": "Pyrimidine metabolism", "name": "5,6-Dihydrothymine amidohydrolase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R03055", "ec-code": "3.5.2.2", "sbo": "SBO:0000176"}, "metabolites": {"h_c": 1.0, "56dthm_c": -1.0, "h2o_c": -1.0, "3uib_c": 1.0}, "id": "RC03055", "gene_reaction_rule": "WBGene00000963 or WBGene00000964"}, {"subsystem": "Vitamin B12 metabolism", "name": "Secretion of cobalamin", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"h2o_c": -1.0, "atp_c": -1.0, "cbl1_c": -1.0, "cbl1_e": 1.0, "h_c": 1.0, "adp_c": 1.0, "pi_c": 1.0}, "id": "TCE5105", "gene_reaction_rule": "WBGene00003411"}, {"subsystem": "Transport", "name": "FAD diffusion", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"fad_e": 1.0, "fad_c": -1.0}, "id": "TCE5104", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Uptake of acetylcholine", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"ach_c": 1.0, "ach_e": -1.0}, "id": "TCE5107", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Secretion of acetylcholine", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"h2o_c": -2.0, "atp_c": -2.0, "ach_c": -3.0, "h_c": 2.0, "adp_c": 2.0, "pi_c": 2.0, "ach_e": 3.0}, "id": "TCE5106", "gene_reaction_rule": "WBGene00006756"}, {"subsystem": "Tyrosine metabolism", "name": "4-Hydroxyphenylacetaldehyde:NADP+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R02697", "ec-code": "1.2.1.5", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "nadp_c": -1.0, "nadph_c": 1.0, "h_c": 2.0, "4hoxpacd_c": -1.0, "4hphac_c": 1.0}, "id": "RC02697", "gene_reaction_rule": "WBGene00000111"}, {"subsystem": "Transport", "name": "3-4-Dihydroxyphenylacetate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"34dhpha_c": -1.0, "34dhpha_e": 1.0}, "id": "TCE5108", "gene_reaction_rule": ""}, {"subsystem": "Tyrosine metabolism", "name": "4-Hydroxyphenylacetaldehyde:NAD+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R02695", "ec-code": "1.2.1.5", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "h_c": 2.0, "nad_c": -1.0, "4hoxpacd_c": -1.0, "4hphac_c": 1.0, "nadh_c": 1.0}, "id": "RC02695", "gene_reaction_rule": "WBGene00000111"}, {"subsystem": "Valine, leucine and isoleucine degradation", "name": "Methylmalonyl-CoA epimerase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R02765", "ec-code": "5.1.99.1", "sbo": "SBO:0000176"}, "metabolites": {"mmcoa-S_m": 1.0, "mmcoa-R_m": -1.0}, "id": "RM02765", "gene_reaction_rule": "WBGene00008415"}, {"subsystem": "Arachidonic acid metabolism", "name": "Arachidonate 5-lipoxygenase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03058", "ec-code": "1.13.11.34", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": 1.0, "leuktrA4_c": 1.0, "5HPET_c": -1.0}, "id": "RC03058", "gene_reaction_rule": ""}, {"subsystem": "Propanoate metabolism", "name": "malonyl-CoA carboxy-lyase (acetyl-CoA-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00233", "ec-code": "4.1.1.9", "sbo": "SBO:0000176"}, "metabolites": {"malcoa_c": -1.0, "co2_c": 1.0, "h_c": -1.0, "accoa_c": 1.0}, "id": "RC00233", "gene_reaction_rule": "WBGene00009439"}, {"subsystem": "Glycolysis / Gluconeogenesis", "name": "Acetate:CoA ligase (AMP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00235", "ec-code": "6.2.1.1", "sbo": "SBO:0000176"}, "metabolites": {"atp_c": -1.0, "ppi_c": 1.0, "coa_c": -1.0, "amp_c": 1.0, "accoa_c": 1.0, "ac_c": -1.0}, "id": "RC00235", "gene_reaction_rule": "WBGene00007969"}, {"subsystem": "Fatty acid metabolism", "name": "Acetyl-CoA:acetyl-CoA C-acetyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00238", "ec-code": "2.3.1.9", "sbo": "SBO:0000176"}, "metabolites": {"aacoa_c": 1.0, "coa_c": 1.0, "accoa_c": -2.0}, "id": "RC00238", "gene_reaction_rule": "WBGene00020166"}, {"subsystem": "Exchange with the environment", "name": "Ubiquinone-8 exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"q8_e": -1.0}, "id": "EXC0013", "gene_reaction_rule": ""}, {"subsystem": "Biosynthesis of unsaturated fatty acids", "name": "DELTA6-fatty-acid desaturase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R07933", "ec-code": "1.14.19.3", "sbo": "SBO:0000176"}, "metabolites": {"strdnccoa_c": 1.0, "o2_c": -1.0, "h2o_c": 2.0, "ficytb_c": 2.0, "focytb_c": -2.0, "lnlncacoa_c": -1.0}, "id": "RC07933", "gene_reaction_rule": "WBGene00001395"}, {"subsystem": "Exchange with the environment", "name": "Thiosulfate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"tsul_e": -1.0}, "id": "EX00320", "gene_reaction_rule": ""}, {"subsystem": "Aminoacyl-tRNA biosynthesis", "name": "L-serine:tRNASec ligase (AMP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R08218", "ec-code": "6.1.1.11", "sbo": "SBO:0000176"}, "metabolites": {"ser-L_c": -1.0, "atp_c": -1.0, "ppi_c": 1.0, "sertrna_sec_c": 1.0, "amp_c": 1.0, "trnasec_c": -1.0}, "id": "RC08218", "gene_reaction_rule": "WBGene00005663"}, {"subsystem": "Purine metabolism", "name": "1-(5-Phosphoribosyl)-5-amino-4-carboxyimidazole:L-aspartate ligase (ADP-forming)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R04591", "ec-code": "6.3.2.6", "sbo": "SBO:0000176"}, "metabolites": {"atp_c": -1.0, "5aizc_c": -1.0, "25aics_c": 1.0, "h_c": 1.0, "adp_c": 1.0, "pi_c": 1.0, "asp-L_c": -1.0}, "id": "RC04591", "gene_reaction_rule": "WBGene00015116"}, {"subsystem": "Exchange with the environment", "name": "Bicarbonate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"hco3_e": -1.0}, "id": "EX00288", "gene_reaction_rule": ""}, {"subsystem": "Glycine, serine and threonine metabolism", "name": "dihydrolipoylprotein:NAD+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R03815", "ec-code": "1.8.1.4", "sbo": "SBO:0000176"}, "metabolites": {"nad_m": -1.0, "dhlpro_m": -1.0, "h_m": 1.0, "lpro_m": 1.0, "nadh_m": 1.0}, "id": "RM03815", "gene_reaction_rule": "WBGene00010794 and (WBGene00008354 or WBGene00009918)"}, {"subsystem": "Valine, leucine and isoleucine degradation", "name": "3-Hydroxy-2-methylpropanoate:NAD+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R05066", "ec-code": ["1.1.1.31", "1.1.1.35"], "sbo": "SBO:0000176"}, "metabolites": {"3hmp_m": -1.0, "nad_m": -1.0, "h_m": 1.0, "nadh_m": 1.0, "2mop_m": 1.0}, "id": "RM05066", "gene_reaction_rule": "WBGene00007122 or (WBGene00007129 or WBGene00010035 or WBGene00001157 or WBGene00001158 or WBGene00019978)"}, {"subsystem": "Valine, leucine and isoleucine degradation", "name": "(S)-3-Hydroxyisobutyryl-CoA hydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R05064", "ec-code": "3.1.2.4", "sbo": "SBO:0000176"}, "metabolites": {"3hmp_m": 1.0, "3hibutcoa_m": -1.0, "coa_m": 1.0, "h_m": 1.0, "h2o_m": -1.0}, "id": "RM05064", "gene_reaction_rule": "WBGene00017301"}, {"subsystem": "Galactose metabolism", "name": "Stachyose galactohydrolase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R03634", "ec-code": "3.2.1.22", "sbo": "SBO:0000176"}, "metabolites": {"raffin_c": 1.0, "h2o_c": -1.0, "gal_c": 1.0, "stachyose_c": -1.0}, "id": "RC03634", "gene_reaction_rule": "WBGene00011095"}, {"subsystem": "Transport", "name": "propionate transfer between mitochondria and cytosol", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"ppa_c": -1.0, "ppa_m": 1.0}, "id": "TCM5034", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Bacterial ubiquinone transport (cytosol/mitochondria)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"q8_m": 1.0, "q8_c": -1.0}, "id": "TCM5037", "gene_reaction_rule": ""}, {"subsystem": "Pyrimidine metabolism", "name": "N-Carbamoyl-beta-alanine amidohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00905", "ec-code": "3.5.1.6", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "cala_c": -1.0, "h_c": -2.0, "ala-B_c": 1.0, "co2_c": 1.0, "nh4_c": 1.0}, "id": "RC00905", "gene_reaction_rule": "WBGene00017440"}, {"subsystem": "Transport", "name": "alanine transport into mitochondria", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"ala-L_c": -1.0, "ala-L_m": 1.0}, "id": "TCM5030", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "all-trans-Nonaprenyl diphosphate transport into mitochondria", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"nonadp_m": 1.0, "nonadp_c": -1.0}, "id": "TCM5032", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "1-Alkyl-2-lyso-sn-glycero-3-phosphocholine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"ak2lgchol_e": -1.0}, "id": "EX04317", "gene_reaction_rule": ""}, {"subsystem": "Primary bile acid biosynthesis", "name": "7alpha,25-Dihydroxy-4-cholesten-3-one demand", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"xol25one_c": -1.0}, "id": "DMN0078", "gene_reaction_rule": ""}, {"subsystem": "Folate biosynthesis", "name": "Dihydroneopterin demand", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"dhnpt_c": -1.0}, "id": "DMN0077", "gene_reaction_rule": ""}, {"subsystem": "N-Glycan biosynthesis", "name": "Dolichyl phosphate demand", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"dolp_c": -1.0}, "id": "DMN0075", "gene_reaction_rule": ""}, {"subsystem": "Selenocompound metabolism", "name": "Selenoprotein synthesis (single aminoacid)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"h2o_c": -2.324, "gdp_c": 2.0, "atp_c": -0.324, "sectrna_c": -1.0, "gtp_c": -2.0, "h_c": 3.324, "adp_c": 0.324, "pi_c": 2.324, "trnasec_c": 1.0}, "id": "DMN0073", "gene_reaction_rule": "WBGene00015553"}, {"subsystem": "Protein modification by hydroxylation", "name": "3-hydroxy-L-arginine demand", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"asn-L_c": 1.0, "pepasn3oh_c": -1.0, "h2o_c": -1.0, "pepX_c": 1.0}, "id": "DMN0072", "gene_reaction_rule": ""}, {"subsystem": "Glycine, serine and threonine metabolism", "name": "O-phospho-L-serine phosphohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00582", "ec-code": "3.1.3.3", "sbo": "SBO:0000176"}, "metabolites": {"ser-L_c": 1.0, "h2o_c": -1.0, "pi_c": 1.0, "pser-L_c": -1.0}, "id": "RC00582", "gene_reaction_rule": "WBGene00013379"}, {"subsystem": "Transport", "name": "Adenine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"ade_c": -1.0, "ade_m": 1.0}, "id": "TCM1053", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "L-Tryptophan transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"trp-L_m": 1.0, "trp-L_c": -1.0}, "id": "TCM1051", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "L-erythro-4-Hydroxyglutamate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"e4hglu_c": -1.0, "e4hglu_m": 1.0}, "id": "TCM1055", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "L-Histidine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"his-L_m": -1.0, "his-L_c": 1.0}, "id": "TCM1054", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "5-Phospho-alpha-D-ribose 1-diphosphate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"prpp_m": 1.0, "prpp_c": -1.0}, "id": "TCM1059", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "L-Methionine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"met-L_m": -1.0, "met-L_c": 1.0}, "id": "TCM1058", "gene_reaction_rule": ""}, {"subsystem": "Citrate cycle (TCA cycle)", "name": "(S)-malate:NAD+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00342", "ec-code": "1.1.1.37", "sbo": "SBO:0000176"}, "metabolites": {"mal-L_c": -1.0, "nadh_c": 1.0, "oaa_c": 1.0, "nad_c": -1.0, "h_c": 1.0}, "id": "RC00342", "gene_reaction_rule": "WBGene00018491"}, {"subsystem": "Arginine and proline metabolism", "name": "4-acetamidobutanoate amidohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01987", "ec-code": "3.5.1.63", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "4aabutn_c": -1.0, "ac_c": 1.0, "4abut_c": 1.0}, "id": "RC01987", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Octopamine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"octpmn_e": -1.0}, "id": "EX04227", "gene_reaction_rule": ""}, {"subsystem": "Tryptophan metabolism", "name": "L-Kynurenine,NADPH:oxygen oxidoreductase (3-hydroxylating)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01960", "ec-code": "1.14.13.9", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "h2o_c": 1.0, "nadp_c": 1.0, "nadph_c": -1.0, "hLkynr_c": 1.0, "h_c": -1.0, "Lkynr_c": -1.0}, "id": "RC01960", "gene_reaction_rule": "WBGene00011088 or WBGene00011089"}, {"subsystem": "Amino sugar and nucleotide sugar metabolism", "name": "ATP:D-glucosamine 6-phosphotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01961", "ec-code": "2.7.1.1", "sbo": "SBO:0000176"}, "metabolites": {"gam6p_c": 1.0, "gam_c": -1.0, "adp_c": 1.0, "atp_c": -1.0, "h_c": 1.0}, "id": "RC01961", "gene_reaction_rule": "WBGene00008780 or WBGene00010416 or WBGene00022306"}, {"subsystem": "Aminoacyl-tRNA biosynthesis", "name": "L-Alanine:tRNA(Ala) ligase (AMP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03038", "ec-code": "6.1.1.7", "sbo": "SBO:0000176"}, "metabolites": {"ala-L_m": -1.0, "atp_m": -1.0, "trnaala_m": -1.0, "alatrna_m": 1.0, "ppi_m": 1.0, "amp_m": 1.0}, "id": "RM03038", "gene_reaction_rule": "WBGene00000196"}, {"subsystem": "Pantothenate and CoA biosynthesis", "name": "ATP:pantetheine-4-phosphate adenylyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R03035", "ec-code": "2.7.7.3", "sbo": "SBO:0000176"}, "metabolites": {"atp_m": -1.0, "ppi_m": 1.0, "h_m": -1.0, "dpcoa_m": 1.0, "pan4p_m": -1.0}, "id": "RM03035", "gene_reaction_rule": "WBGene00022031"}, {"subsystem": "Purine metabolism", "name": "2-Deoxyguanosine 5-monophosphate phosphohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01968", "ec-code": "3.1.3.5", "sbo": "SBO:0000176"}, "metabolites": {"dgsn_c": 1.0, "h2o_c": -1.0, "pi_c": 1.0, "dgmp_c": -1.0}, "id": "RC01968", "gene_reaction_rule": "WBGene00017775 or WBGene00012423 or WBGene00022201"}, {"subsystem": "Purine metabolism", "name": "Deoxyguanosine:orthophosphate ribosyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01969", "ec-code": "2.4.2.1", "sbo": "SBO:0000176"}, "metabolites": {"dgsn_c": -1.0, "2dr1p_c": 1.0, "pi_c": -1.0, "gua_c": 1.0}, "id": "RC01969", "gene_reaction_rule": "WBGene00019298"}, {"subsystem": "Exchange with the environment", "name": "retinoyl glucuronide exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"retnglc_e": -1.0}, "id": "EX11061", "gene_reaction_rule": ""}, {"subsystem": "Phenylalanine metabolism", "name": "L-phenylalanine carboxy-lyase (phenylethylamine-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00699", "ec-code": "4.1.1.28", "sbo": "SBO:0000176"}, "metabolites": {"co2_c": 1.0, "h_c": -1.0, "peamn_c": 1.0, "phe-L_c": -1.0}, "id": "RC00699", "gene_reaction_rule": "WBGene00000239 or WBGene00001839 or WBGene00006562"}, {"subsystem": "Phenylalanine metabolism", "name": "L-phenylalanine:oxygen oxidoreductase (decarboxylating)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00698", "ec-code": "1.11.1.7", "sbo": "SBO:0000176"}, "metabolites": {"pad_c": 1.0, "o2_c": -1.0, "h2o_c": 1.0, "co2_c": 1.0, "phe-L_c": -1.0}, "id": "RC00698", "gene_reaction_rule": "WBGene00021401"}, {"subsystem": "Inositol phosphate metabolism", "name": "1D-myo-Inositol 4-phosphate phosphohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01186", "ec-code": "3.1.3.25", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "mi4p-D_c": -1.0, "inost_c": 1.0, "pi_c": 1.0}, "id": "RC01186", "gene_reaction_rule": "(WBGene00008765 or WBGene00012390)"}, {"subsystem": "Inositol phosphate metabolism", "name": "1D-myo-Inositol 3-phosphate phosphohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01187", "ec-code": "3.1.3.25", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "pi_c": 1.0, "inost_c": 1.0, "mi3p-D_c": -1.0}, "id": "RC01187", "gene_reaction_rule": "(WBGene00008765 or WBGene00012390)"}, {"subsystem": "Fatty acid metabolism", "name": "fatty-acid--CoA ligase (fa17c9)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00390", "ec-code": "6.2.1.3", "sbo": "SBO:0000176"}, "metabolites": {"fa17c9coa_c": 1.0, "atp_c": -1.0, "ppi_c": 1.0, "coa_c": -1.0, "amp_c": 1.0, "fa17c9_c": -1.0}, "id": "RCC0148", "gene_reaction_rule": "WBGene00009221 or WBGene00020343 or WBGene00018152 or WBGene00013575 or WBGene00022037 or WBGene00019920 or WBGene00016716 or WBGene00011173"}, {"subsystem": "Fatty acid metabolism", "name": "fatty-acid--CoA ligase (fa19c11)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00390", "ec-code": "6.2.1.3", "sbo": "SBO:0000176"}, "metabolites": {"fa19c11_c": -1.0, "atp_c": -1.0, "ppi_c": 1.0, "coa_c": -1.0, "amp_c": 1.0, "fa19c11coa_c": 1.0}, "id": "RCC0149", "gene_reaction_rule": "WBGene00009221 or WBGene00020343 or WBGene00018152 or WBGene00013575 or WBGene00022037 or WBGene00019920 or WBGene00016716 or WBGene00011173"}, {"subsystem": "Fatty acid metabolism", "name": "fatty-acid--CoA ligase (fa16p1n7)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00390", "ec-code": "6.2.1.3", "sbo": "SBO:0000176"}, "metabolites": {"fa16p1n7_c": -1.0, "atp_c": -1.0, "ppi_c": 1.0, "coa_c": -1.0, "amp_c": 1.0, "fa16p1n7coa_c": 1.0}, "id": "RCC0147", "gene_reaction_rule": "WBGene00009221 or WBGene00020343 or WBGene00018152 or WBGene00013575 or WBGene00022037 or WBGene00019920 or WBGene00016716 or WBGene00011173"}, {"subsystem": "Retinol metabolism", "name": "retinol isomerase (9-cis)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"retinol_c": -1.0, "retinol-9-cis_c": 1.0}, "id": "RCC0144", "gene_reaction_rule": ""}, {"subsystem": "Fatty acid biosynthesis", "name": "fatty acid synthetase (n-C14:0)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R05188", "ec-code": "2.3.1.85", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": 5.0, "malcoa_c": -6.0, "nadph_c": -12.0, "nadp_c": 12.0, "coa_c": 7.0, "h_c": -17.0, "accoa_c": -1.0, "co2_c": 6.0, "ttdca_c": 1.0}, "id": "RCC0145", "gene_reaction_rule": "WBGene00009342"}, {"subsystem": "Molybdenum cofactor biosynthesis", "name": "molybdopterin synthesis-merged", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R07460", "R09395"], "ec-code": ["2.8.1.7", "2.7.7.80", "2.8.1.11", "2.8.1.12"], "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "atp_c": -2.0, "h_c": 4.0, "molybd_c": 1.0, "ala-L_c": 2.0, "cpmp_c": -1.0, "ppi_c": 2.0, "trdrd_c": -2.0, "cys-L_c": -2.0, "trdox_c": 2.0, "amp_c": 2.0}, "id": "RCC0142", "gene_reaction_rule": "WBGene00015021 and WBGene00018357 and (WBGene00020842 and WBGene00019633)"}, {"subsystem": "Molybdenum cofactor biosynthesis", "name": "molybdopterin adenylyl transferase; molybdopterin molybdotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R09726", "R09735"], "ec-code": ["2.7.7.75", "2.10.1.1"], "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": 1.0, "atp_c": -1.0, "mobd_c": -1.0, "molybd_c": -1.0, "moco_c": 1.0, "amp_c": 1.0, "ppi_c": 1.0, "h_c": -2.0}, "id": "RCC0143", "gene_reaction_rule": "WBGene00003031 or WBGene00003384 or WBGene00003385"}, {"subsystem": "Degradation of alkylacylglycerolipids", "name": "glyceryl-ether monoxygenase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R04044", "ec-code": "1.14.16.5", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "h2o_c": 1.0, "thbpt_c": -1.0, "ak2lgchol_c": -1.0, "dhbpt_c": 1.0, "hak2lgchol_c": 1.0}, "id": "RCC0140", "gene_reaction_rule": "WBGene00007210"}, {"subsystem": "Degradation of alkylacylglycerolipids", "name": "Hydroxyalkyl-sn-glycerol decomposition", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"hak2lgchol_c": -1.0, "g3pc_c": 1.0, "fattyald_c": 1.0}, "id": "RCC0141", "gene_reaction_rule": ""}, {"subsystem": "Citrate cycle (TCA cycle)", "name": "Succinate:CoA ligase (GDP-forming)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00432", "ec-code": "6.2.1.4", "sbo": "SBO:0000176"}, "metabolites": {"succoa_m": 1.0, "gdp_m": 1.0, "pi_m": 1.0, "gtp_m": -1.0, "succ_m": -1.0, "coa_m": -1.0}, "id": "RM00432", "gene_reaction_rule": "(WBGene00007350 or WBGene00017759) and WBGene00016844"}, {"subsystem": "Peroxisomal fatty acid beta oxidation", "name": "Beta oxidation of vaccenic acid (peroxisomal)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R00388", "R01778", "R00391"], "ec-code": ["1.3.3.6", "5.3.3.8", "4.2.1.17", "1.1.1.211", "1.1.1.35", "2.3.1.16"], "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -4.0, "h2o_c": -5.0, "nad_c": -5.0, "vacccoa_c": -1.0, "h2o2_c": 4.0, "coa_c": -5.0, "h_c": 5.0, "accoa_c": 5.0, "nadh_c": 5.0, "occoa_c": 1.0}, "id": "RCC0090", "gene_reaction_rule": "(WBGene00008167 or WBGene00008564 or WBGene00008565 or WBGene00008566 or WBGene00008567 or WBGene00019060 or WBGene00010336) and WBGene00019022 and (WBGene00000991 or WBGene00017123) and WBGene00013284"}, {"subsystem": "Peroxisomal fatty acid beta oxidation", "name": "Beta oxidation of linoleic acid (peroxisomal)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R00388", "R02685", "R01778", "R00391"], "ec-code": ["1.3.3.6", "4.2.1.17", "1.1.1.211", "1.1.1.35", "2.3.1.16"], "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -2.0, "h2o_c": -2.0, "nad_c": -2.0, "lnlccoa_c": -1.0, "h2o2_c": 2.0, "fa14p2n6coa_c": 1.0, "coa_c": -2.0, "h_c": 2.0, "accoa_c": 2.0, "nadh_c": 2.0}, "id": "RCC0091", "gene_reaction_rule": "(WBGene00008167 or WBGene00008564 or WBGene00008565 or WBGene00008566 or WBGene00008567 or WBGene00019060 or WBGene00010336) and (WBGene00000991 or WBGene00017123) and WBGene00013284"}, {"subsystem": "Peroxisomal fatty acid beta oxidation", "name": "Beta oxidation of intermediary fatty acid C14:2 (peroxisomal)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R00388", "R04319", "R03224", "R02685", "R01778", "R00391"], "ec-code": ["1.3.3.6", "5.3.3.8", "1.3.1.34", "4.2.1.17", "1.1.1.211", "1.1.1.35", "2.3.1.16"], "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -2.0, "h2o_c": -3.0, "nadp_c": 1.0, "nadph_c": -1.0, "accoa_c": 3.0, "h2o2_c": 2.0, "fa14p2n6coa_c": -1.0, "coa_c": -3.0, "h_c": 2.0, "nad_c": -3.0, "nadh_c": 3.0, "occoa_c": 1.0}, "id": "RCC0092", "gene_reaction_rule": "(WBGene00008167 or WBGene00008564 or WBGene00008565 or WBGene00008566 or WBGene00008567 or WBGene00019060 or WBGene00010336) and WBGene00019022 and WBGene00009973 and (WBGene00000991 or WBGene00017123) and WBGene00013284"}, {"subsystem": "Peroxisomal fatty acid beta oxidation", "name": "Beta oxidation of eicosatrieonic acid (peroxisomal)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R00388", "R03224", "R02685", "R01778", "R00391"], "ec-code": ["1.3.3.6", "4.2.1.17", "1.1.1.211", "1.1.1.35", "2.3.1.16"], "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -2.0, "h2o_c": -2.0, "accoa_c": 2.0, "dlnlcgcoa_c": -1.0, "fa16p3n6coa_c": 1.0, "h2o2_c": 2.0, "coa_c": -2.0, "h_c": 2.0, "nad_c": -2.0, "nadh_c": 2.0}, "id": "RCC0093", "gene_reaction_rule": "(WBGene00008167 or WBGene00008564 or WBGene00008565 or WBGene00008566 or WBGene00008567 or WBGene00019060 or WBGene00010336) and (WBGene00000991 or WBGene00017123) and WBGene00013284"}, {"subsystem": "Peroxisomal fatty acid beta oxidation", "name": "Beta oxidation of intermediary fatty acid C16:3 (peroxisomal)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R00388", "R04319", "R03224", "R02685", "R01778", "R00391"], "ec-code": ["1.3.3.6", "5.3.3.8", "1.3.1.34", "4.2.1.17", "1.1.1.211", "1.1.1.35", "2.3.1.16"], "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "h2o_c": -1.0, "nadp_c": 1.0, "nadph_c": -1.0, "accoa_c": 1.0, "fa16p3n6coa_c": -1.0, "h2o2_c": 1.0, "fa14p2n6coa_c": 1.0, "coa_c": -1.0, "nad_c": -1.0, "nadh_c": 1.0}, "id": "RCC0094", "gene_reaction_rule": "(WBGene00008167 or WBGene00008564 or WBGene00008565 or WBGene00008566 or WBGene00008567 or WBGene00019060 or WBGene00010336) and WBGene00019022 and WBGene00009973 and (WBGene00000991 or WBGene00017123) and WBGene00013284"}, {"subsystem": "Peroxisomal fatty acid beta oxidation", "name": "Beta oxidation of arachidonic acid (peroxisomal)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R00388", "R03224", "R02685", "R01778", "R00391"], "ec-code": ["1.3.3.6", "5.3.3.8", "4.2.1.17", "1.1.1.211", "1.1.1.35", "2.3.1.16"], "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "h2o_c": -2.0, "nad_c": -2.0, "fa16p3n6coa_c": 1.0, "h2o2_c": 1.0, "coa_c": -2.0, "h_c": 2.0, "accoa_c": 2.0, "arachdcoa_c": -1.0, "nadh_c": 2.0}, "id": "RCC0095", "gene_reaction_rule": "(WBGene00008167 or WBGene00008564 or WBGene00008565 or WBGene00008566 or WBGene00008567 or WBGene00019060 or WBGene00010336) and WBGene00019022 and (WBGene00000991 or WBGene00017123) and WBGene00013284"}, {"subsystem": "Peroxisomal fatty acid beta oxidation", "name": "Beta oxidation of eicosatetraeonic acid (peroxisomal)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R00388", "R03224", "R02685", "R01778", "R00391"], "ec-code": ["1.3.3.6", "4.2.1.17", "1.1.1.211", "1.1.1.35", "2.3.1.16"], "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -2.0, "h2o_c": -2.0, "accoa_c": 2.0, "eicostetcoa_c": -1.0, "h2o2_c": 2.0, "coa_c": -2.0, "h_c": 2.0, "nad_c": -2.0, "nadh_c": 2.0, "fa16p4n3coa_c": 1.0}, "id": "RCC0096", "gene_reaction_rule": "(WBGene00008167 or WBGene00008564 or WBGene00008565 or WBGene00008566 or WBGene00008567 or WBGene00019060 or WBGene00010336) and (WBGene00000991 or WBGene00017123) and WBGene00013284"}, {"subsystem": "Peroxisomal fatty acid beta oxidation", "name": "Beta oxidation of intermediary fatty acid C16:4 (peroxisomal)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R00388", "R04319", "R03224", "R02685", "R01778", "R00391"], "ec-code": ["1.3.3.6", "5.3.3.8", "1.3.1.34", "4.2.1.17", "1.1.1.211", "1.1.1.35", "2.3.1.16"], "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -3.0, "h2o_c": -4.0, "nadp_c": 2.0, "nadph_c": -2.0, "fa16p4n3coa_c": -1.0, "fa8p1n3coa_c": 1.0, "h2o2_c": 3.0, "coa_c": -4.0, "h_c": 2.0, "nad_c": -4.0, "nadh_c": 4.0, "accoa_c": 4.0}, "id": "RCC0097", "gene_reaction_rule": "(WBGene00008167 or WBGene00008564 or WBGene00008565 or WBGene00008566 or WBGene00008567 or WBGene00019060 or WBGene00010336) and WBGene00019022 and WBGene00009973 and (WBGene00000991 or WBGene00017123) and WBGene00013284"}, {"subsystem": "Peroxisomal fatty acid beta oxidation", "name": "Beta oxidation of eicosapentanoic acid (peroxisomal)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R00388", "R03224", "R02685", "R01778", "R00391"], "ec-code": ["1.3.3.6", "5.3.3.8", "4.2.1.17", "1.1.1.211", "1.1.1.35", "2.3.1.16"], "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "h2o_c": -2.0, "nad_c": -2.0, "tmndnccoa_c": -1.0, "h2o2_c": 1.0, "coa_c": -2.0, "h_c": 2.0, "accoa_c": 2.0, "nadh_c": 2.0, "fa16p4n3coa_c": 1.0}, "id": "RCC0098", "gene_reaction_rule": "(WBGene00008167 or WBGene00008564 or WBGene00008565 or WBGene00008566 or WBGene00008567 or WBGene00019060 or WBGene00010336) and WBGene00019022 and (WBGene00000991 or WBGene00017123) and WBGene00013284"}, {"subsystem": "Carnitine shuttle", "name": "Acyl-CoA:L-carnitine O-acyltransferase I (intermediary fatty acyl [C8:1]-CoA)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "2.3.1.137", "sbo": "SBO:0000176"}, "metabolites": {"crn_c": -1.0, "fa8p1n3crn_c": 1.0, "coa_c": 1.0, "fa8p1n3coa_c": -1.0}, "id": "RCC0099", "gene_reaction_rule": "WBGene00009622 or WBGene00011850"}, {"subsystem": "Amino sugar and nucleotide sugar metabolism", "name": "D-glucosamine-6-phosphate aminohydrolase (ketol isomerizing)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00765", "ec-code": "3.5.99.6", "sbo": "SBO:0000176"}, "metabolites": {"gam6p_c": -1.0, "nh4_c": 1.0, "h2o_c": -1.0, "f6p_c": 1.0}, "id": "RC00765", "gene_reaction_rule": "WBGene00011399"}, {"subsystem": "Primary bile acid biosynthesis", "name": " cholestanetriol 26-monooxygenase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R08759", "ec-code": "1.14.13.15", "sbo": "SBO:0000176"}, "metabolites": {"xoltetrol_c": -1.0, "nadp_c": -1.0, "nadph_c": 1.0, "h_c": 1.0, "thcholst_c": 1.0}, "id": "RC08759", "gene_reaction_rule": "WBGene00000905"}, {"subsystem": "Tyrosine metabolism", "name": "4-fumarylacetoacetate fumarylhydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01364", "ec-code": "3.7.1.2", "sbo": "SBO:0000176"}, "metabolites": {"4fumacac_c": -1.0, "acac_c": 1.0, "h2o_c": -1.0, "fum_c": 1.0, "h_c": 1.0}, "id": "RC01364", "gene_reaction_rule": "WBGene00019620"}, {"subsystem": "Alanine, aspartate and glutamate metabolism", "name": "L-glutamine:D-fructose-6-phosphate isomerase (deaminating)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00768", "ec-code": "2.6.1.16", "sbo": "SBO:0000176"}, "metabolites": {"glu-L_c": 1.0, "gam6p_c": 1.0, "gln-L_c": -1.0, "f6p_c": -1.0}, "id": "RC00768", "gene_reaction_rule": "WBGene00008546 or WBGene00009035"}, {"subsystem": "Transport", "name": "Fe2+ transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"fe2_c": 1.0, "fe2_e": -1.0}, "id": "TCE0504", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "ADPribose exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"adprib_e": -1.0}, "id": "EX00301", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Soluble pool in bacterial diet exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"soluble_BAC_e": -1.0}, "id": "EXC0072", "gene_reaction_rule": ""}, {"subsystem": "Riboflavin metabolism", "name": "riboflavin kinase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00549", "ec-code": "2.7.1.26", "sbo": "SBO:0000176"}, "metabolites": {"atp_m": -1.0, "ribflv_m": -1.0, "fmn_m": 1.0, "adp_m": 1.0, "h_m": 1.0}, "id": "RM00549", "gene_reaction_rule": "WBGene00011224"}, {"subsystem": "Transport", "name": "D-Lactate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"lac-D_c": -1.0, "lac-D_m": 1.0}, "id": "TCM1279", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "O-Acetylcarnitine transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"acrn_c": -1.0, "acrn_m": 1.0}, "id": "TCM1278", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Phosphoenolpyruvate and Citrate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"pep_c": 1.0, "cit_m": 1.0, "pep_m": -1.0, "cit_c": -1.0}, "id": "TCM1277", "gene_reaction_rule": "WBGene00010780 or WBGene00021345"}, {"subsystem": "Transport", "name": "H2O transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"h2o_c": -1.0, "h2o_m": 1.0}, "id": "TCM1276", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "O2 transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"o2_c": -1.0, "o2_m": 1.0}, "id": "TCM1275", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Ornithine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"orn_m": -1.0, "orn_c": 1.0}, "id": "TCM1274", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "\"3',5'-Cyclic GMP\" exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"35cgmp_e": -1.0}, "id": "EX00942", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "alpha-Ketoglutaramate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"akgm_e": -1.0}, "id": "EX00940", "gene_reaction_rule": ""}, {"subsystem": "Carnitine shuttle", "name": "Acyl-CoA:L-carnitine O-acyltransferase I (Stearoyl-CoA )", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "2.3.1.21", "sbo": "SBO:0000176"}, "metabolites": {"crn_c": -1.0, "stcoa_c": -1.0, "coa_c": 1.0, "stcrn_c": 1.0}, "id": "RCC0116", "gene_reaction_rule": "WBGene00012907 or WBGene00021703 or WBGene00019644 or WBGene00008629 or WBGene00020911"}, {"subsystem": "Carnitine shuttle", "name": "Acyl-CoA:L-carnitine O-acyltransferase I (dihomo-gamma-linolenyl CoA)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "2.3.1.21", "sbo": "SBO:0000176"}, "metabolites": {"crn_c": -1.0, "dlnlcgcrn_c": 1.0, "coa_c": 1.0, "dlnlcgcoa_c": -1.0}, "id": "RCC0111", "gene_reaction_rule": "WBGene00012907 or WBGene00021703 or WBGene00019644 or WBGene00008629 or WBGene00020911"}, {"subsystem": "Sulfur metabolism", "name": "Thiosulfate:thiol sulfurtransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01875", "ec-code": "2.8.1.3", "sbo": "SBO:0000176"}, "metabolites": {"h2s_m": -1.0, "gthox_m": -1.0, "tsul_m": 1.0, "so3_m": -1.0, "gthrd_m": 2.0}, "id": "RM01875", "gene_reaction_rule": ""}, {"subsystem": "Pyrimidine metabolism", "name": "Thymidylate 5-phosphohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01569", "ec-code": "3.1.3.5", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "dtmp_c": -1.0, "pi_c": 1.0, "thymd_c": 1.0}, "id": "RC01569", "gene_reaction_rule": "WBGene00017775 or WBGene00012423 or WBGene00022201"}, {"subsystem": "Exchange with the environment", "name": "Flavin adenine dinucleotide oxidized exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"fad_e": -1.0}, "id": "EX00016", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "dGDP and dGTP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dgdp_c": 1.0, "dgtp_c": -1.0, "dgdp_m": -1.0, "dgtp_m": 1.0}, "id": "TCM0098", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "dGDP and dCDP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dcdp_m": -1.0, "dgdp_c": -1.0, "dgdp_m": 1.0, "dcdp_c": 1.0}, "id": "TCM0099", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Peptide exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"pepd_e": -1.0}, "id": "EX00012", "gene_reaction_rule": ""}, {"subsystem": "Purine metabolism", "name": "adenosine deaminase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01560", "ec-code": "3.5.4.4", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "nh4_c": 1.0, "adn_c": -1.0, "h_c": -1.0, "ins_c": 1.0}, "id": "RC01560", "gene_reaction_rule": "WBGene00015551 or WBGene00016632"}, {"subsystem": "Purine metabolism", "name": "Adenosine:phosphate alpha-D-ribosyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01561", "ec-code": "2.4.2.1", "sbo": "SBO:0000176"}, "metabolites": {"ade_c": 1.0, "pi_c": -1.0, "adn_c": -1.0, "r1p_c": 1.0}, "id": "RC01561", "gene_reaction_rule": "WBGene00019298"}, {"subsystem": "Transport", "name": "dGTP and ADP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"adp_m": -1.0, "dgtp_c": -1.0, "dgtp_m": 1.0, "adp_c": 1.0}, "id": "TCM0096", "gene_reaction_rule": ""}, {"subsystem": "Carnitine shuttle", "name": "Acyl-CoA:L-carnitine O-acyltransferase I (timnodonyl CoA)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "2.3.1.21", "sbo": "SBO:0000176"}, "metabolites": {"crn_c": -1.0, "tmndnccoa_c": -1.0, "coa_c": 1.0, "tmndnccrn_c": 1.0}, "id": "RCC0112", "gene_reaction_rule": "WBGene00012907 or WBGene00021703 or WBGene00019644 or WBGene00008629 or WBGene00020911"}, {"subsystem": "Transport", "name": "Pyridoxamine 5'-phosphate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"pyam5p_c": -1.0, "pyam5p_m": 1.0}, "id": "TCM0090", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "ATP and dCDP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"atp_m": -1.0, "dcdp_m": 1.0, "atp_c": 1.0, "dcdp_c": -1.0}, "id": "TCM0091", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "dTTP and ADP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"adp_m": -1.0, "dttp_m": 1.0, "dttp_c": -1.0, "adp_c": 1.0}, "id": "TCM0092", "gene_reaction_rule": ""}, {"subsystem": "Pyrimidine metabolism", "name": "ATP:thymidine 5-phosphotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01567", "ec-code": "2.7.1.21", "sbo": "SBO:0000176"}, "metabolites": {"h_c": 1.0, "dtmp_c": 1.0, "adp_c": 1.0, "atp_c": -1.0, "thymd_c": -1.0}, "id": "RC01567", "gene_reaction_rule": "WBGene00006568"}, {"subsystem": "Exchange with the environment", "name": "Urocanate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"urcan_e": -1.0}, "id": "EX00785", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Serotonin exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"srtn_e": -1.0}, "id": "EX00780", "gene_reaction_rule": ""}, {"subsystem": "Miscellaneous", "name": "thiosulfate:cyanide sulfurtranserase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01931", "ec-code": "2.8.1.1", "sbo": "SBO:0000176"}, "metabolites": {"so3_c": 1.0, "tcynt_c": 1.0, "tsul_c": -1.0, "cyan_c": -1.0, "h_c": 1.0}, "id": "RC01931", "gene_reaction_rule": "WBGene00008409 or WBGene00010380 or WBGene00010383 or WBGene00017387 or WBGene00022006 or WBGene00022007 or WBGene00011307"}, {"subsystem": "Taurine and hypotaurine metabolism", "name": "3-Sulfino-L-alanine carboxy-lyase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02466", "ec-code": "4.1.1.15", "sbo": "SBO:0000176"}, "metabolites": {"co2_c": 1.0, "hyptaur_c": 1.0, "h_c": -1.0, "3sala_c": -1.0}, "id": "RC02466", "gene_reaction_rule": "WBGene00006762"}, {"subsystem": "Exchange with the environment", "name": "IMP exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"imp_e": -1.0}, "id": "EX00130", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Bicarbonate and Prostaglandin D2 transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"hco3_c": -1.0, "hco3_e": 1.0, "prostgd2_c": 1.0, "prostgd2_e": -1.0}, "id": "TCE0729", "gene_reaction_rule": ""}, {"subsystem": "Pantothenate and CoA biosynthesis", "name": "ATP:dephospho-CoA 3-phosphotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00130", "ec-code": "2.7.1.24", "sbo": "SBO:0000176"}, "metabolites": {"atp_m": -1.0, "adp_m": 1.0, "coa_m": 1.0, "h_m": 1.0, "dpcoa_m": -1.0}, "id": "RM00130", "gene_reaction_rule": "WBGene00011500 or WBGene00022031"}, {"subsystem": "Glycine, serine and threonine metabolism", "name": "S-aminomethyldihydrolipoylprotein:(6S)-tetrahydrofolate aminomethyltransferase (ammonia-forming)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R04125", "ec-code": "2.1.2.10", "sbo": "SBO:0000176"}, "metabolites": {"mlthf_m": 1.0, "dhlpro_m": 1.0, "thf_m": -1.0, "nh4_m": 1.0, "alpro_m": -1.0}, "id": "RM04125", "gene_reaction_rule": "WBGene00017765 and (WBGene00008354 or WBGene00009918)"}, {"subsystem": "Transport", "name": "Retinoate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"retn_c": -1.0, "retn_e": 1.0}, "id": "TCE0723", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "4-Acetamidobutanoate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"4aabutn_e": -1.0}, "id": "EX02946", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Urate transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"urate_c": -1.0, "urate_e": 1.0}, "id": "TCE0726", "gene_reaction_rule": ""}, {"subsystem": "Miscellaneous", "name": "inorganic triphosphatase (mitochondrial)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00138", "ec-code": "3.6.1.25", "sbo": "SBO:0000176"}, "metabolites": {"ppi_m": 1.0, "h_m": 1.0, "h2o_m": -1.0, "pi_m": 1.0, "pppi_m": -1.0}, "id": "RM00138", "gene_reaction_rule": ""}, {"subsystem": "Pyrimidine metabolism", "name": "5,6-Dihydrothymine:NADP+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01415", "ec-code": "1.3.1.2", "sbo": "SBO:0000176"}, "metabolites": {"56dthm_c": -1.0, "nadp_c": -1.0, "nadph_c": 1.0, "h_c": 1.0, "thym_c": 1.0}, "id": "RC01415", "gene_reaction_rule": "WBGene00016103"}, {"subsystem": "Transport", "name": "2-Oxoglutarate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"akg_c": 1.0, "akg_e": -1.0}, "id": "TCE1121", "gene_reaction_rule": ""}, {"subsystem": "Cyanoamino acid metabolism", "name": "cyanide conversion to alpha-Aminopropiononitrile", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01410", "sbo": "SBO:0000176"}, "metabolites": {"acald_c": -1.0, "h2o_c": 1.0, "aprop_c": 1.0, "cyan_c": -1.0, "nh4_c": -1.0}, "id": "RC01410", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "D-Sorbitol transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"sbt-D_e": -1.0, "sbt-D_c": 1.0}, "id": "TCE1124", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Glycolate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"glyclt_e": -1.0}, "id": "EX00160", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Propionate (n-C3:0) exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"ppa_e": -1.0}, "id": "EX00163", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "R total exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"Rtotal_e": -1.0}, "id": "EX00162", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Acetoacetate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"acac_e": -1.0}, "id": "EX00164", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "UDP-D-glucuronate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"udpglcur_e": -1.0}, "id": "EX00167", "gene_reaction_rule": ""}, {"subsystem": "Cysteine and methionine metabolism", "name": "3-sulfino-L-alanine:2-oxoglutarate aminotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R02619", "ec-code": "2.6.1.1", "sbo": "SBO:0000176"}, "metabolites": {"3sala_m": -1.0, "h_m": -1.0, "glu-L_m": 1.0, "akg_m": -1.0, "3snpyr_m": 1.0}, "id": "RM02619", "gene_reaction_rule": "WBGene00016652 or WBGene00015778"}, {"subsystem": "Transport", "name": "NMN transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"nmn_m": 1.0, "nmn_c": -1.0}, "id": "TCM1072", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "D-Alanine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"ala-D_c": 1.0, "ala-D_e": -1.0}, "id": "TCE0797", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "\"7-alpha,25-Dihydroxycholesterol\" transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"xoltri25_e": 1.0, "xoltri25_c": -1.0}, "id": "TCE0615", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "5alpha-Dihydrotestosterone transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"5adtststerone_e": -1.0, "5adtststerone_c": 1.0}, "id": "TCE0612", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Sulfate and Chloride transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"cl_e": 1.0, "so4_e": -2.0, "so4_c": 2.0, "cl_c": -1.0}, "id": "TCE0611", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "D-3-Amino-isobutanoate transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"3aib-D_e": 1.0, "3aib-D_c": -1.0}, "id": "TCE0618", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Guanine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"gua_c": 1.0, "gua_e": -1.0}, "id": "TCE0619", "gene_reaction_rule": ""}, {"subsystem": "Arachidonic acid metabolism", "name": "Prostaglandin-H2 D-isomerase (Precursor)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R02266", "ec-code": "5.3.99.2", "sbo": "SBO:0000176"}, "metabolites": {"prostgd2_c": 1.0, "prostgh2_c": -1.0}, "id": "RC02266", "gene_reaction_rule": "WBGene00001759"}, {"subsystem": "Arachidonic acid metabolism", "name": "(5Z,13E)-(15S)-9alpha,11alpha-epidioxy-15-hydroxyprosta-5,13- dienoate E-isomerase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R02265", "ec-code": "5.3.99.3", "sbo": "SBO:0000176"}, "metabolites": {"prostgh2_c": -1.0, "prostge2_c": 1.0}, "id": "RC02265", "gene_reaction_rule": "WBGene00011239 or WBGene00022599"}, {"subsystem": "Pyrimidine metabolism", "name": "5,6-Dihydrouracil amidohydrolase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R02269", "ec-code": "3.5.2.2", "sbo": "SBO:0000176"}, "metabolites": {"h_c": 1.0, "h2o_c": -1.0, "56dura_c": -1.0, "cala_c": 1.0}, "id": "RC02269", "gene_reaction_rule": "WBGene00000963 or WBGene00000964"}, {"subsystem": "Exchange with the environment", "name": "Xanthosine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"xtsn_e": -1.0}, "id": "EX01762", "gene_reaction_rule": ""}, {"subsystem": "Nitrogen metabolism", "name": "carbonate hydro-lyase (carbon-dioxide-forming)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R10092", "ec-code": "4.2.1.1", "sbo": "SBO:0000176"}, "metabolites": {"h_m": 1.0, "h2o_m": -1.0, "co2_m": -1.0, "hco3_m": 1.0}, "id": "RM10092", "gene_reaction_rule": "WBGene00000245 or WBGene00000282"}, {"subsystem": "Tyrosine metabolism", "name": "Homogentisate:oxygen 1,2-oxidoreductase (decyclizing)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02519", "ec-code": "1.13.11.5", "sbo": "SBO:0000176"}, "metabolites": {"hgentis_c": -1.0, "4mlacac_c": 1.0, "h_c": 1.0, "o2_c": -1.0}, "id": "RC02519", "gene_reaction_rule": "WBGene00001843"}, {"subsystem": "Arachidonic acid metabolism", "name": "Glutathione: 5-HPETE oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R07034", "ec-code": "1.11.1.9", "sbo": "SBO:0000176"}, "metabolites": {"5HETE_c": 1.0, "h2o_c": 1.0, "gthox_c": 1.0, "gthrd_c": -2.0, "5HPET_c": -1.0}, "id": "RC07034", "gene_reaction_rule": "WBGene00009165 or WBGene00011045 or WBGene00007517 or WBGene00022377 or WBGene00007516 or WBGene00019846 or WBGene00018850"}, {"subsystem": "Exchange with the environment", "name": "Histone-L-Lysine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"Nlys_e": -1.0}, "id": "EX02415", "gene_reaction_rule": ""}, {"subsystem": "Ether lipid metabolism", "name": "Platelet-activating factor acetylhydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R04452", "ec-code": "3.1.1.47", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "ak2lgchol_c": 1.0, "ac_c": 1.0, "paf_c": -1.0, "h_c": 1.0}, "id": "RC04452", "gene_reaction_rule": "((WBGene00003906 or WBGene00003907) or WBGene00007756) or WBGene00003047"}, {"subsystem": "Cysteine and methionine metabolism", "name": "S-adenosylmethioninamine:spermidine 3-aminopropyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02869", "ec-code": "2.5.1.16", "sbo": "SBO:0000176"}, "metabolites": {"ametam_c": -1.0, "spmd_c": -1.0, "5mta_c": 1.0, "sprm_c": 1.0, "h_c": 1.0}, "id": "RC02869", "gene_reaction_rule": "WBGene00012909"}, {"subsystem": "Exchange with the environment", "name": "Androsterone exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"andrstrn_e": -1.0}, "id": "EX00523", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "L-sulfolactate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"sl-L_e": -1.0}, "id": "EX11499", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "sedoheptulose transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"sedh_c": -1.0, "sedh_e": 1.0}, "id": "TCE5022", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "molybdate transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"mobd_e": -1.0, "h2o_c": -1.0, "atp_c": -1.0, "mobd_c": 1.0, "h_c": 1.0, "adp_c": 1.0, "pi_c": 1.0}, "id": "TCE5023", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "riboflavin transport in via proton symport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"ribflv_e": -1.0, "ribflv_c": 1.0}, "id": "TCE5020", "gene_reaction_rule": "WBGene00044637 or WBGene00021626"}, {"subsystem": "Transport", "name": "2-hydroxyglutarate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"2hglut_e": 1.0, "2hglut_c": -1.0}, "id": "TCE5021", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Hydrogen cyanide transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"cyan_e": -1.0, "cyan_c": 1.0}, "id": "TCE0507", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "beta carotene transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"caro_c": -1.0, "caro_e": 1.0}, "id": "TCE5024", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "beta-Carotene exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"caro_e": -1.0}, "id": "EX02094", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "L-Valine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"val-L_e": -1.0, "val-L_c": 1.0}, "id": "TCE0508", "gene_reaction_rule": ""}, {"subsystem": "Sphingolipid metabolism", "name": "Sphinganine-1-phosphate pamlmitaldehyde-lyase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02464", "ec-code": "4.1.2.27", "sbo": "SBO:0000176"}, "metabolites": {"ethamp_c": 1.0, "m15hxdcal_c": 1.0, "sph1p_ce_c": -1.0}, "id": "RC02464", "gene_reaction_rule": "WBGene00004981 or WBGene00006418"}, {"subsystem": "Glyoxylate and dicarboxylate metabolism", "name": "hydroxypyruvate decarboxylase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01393", "ec-code": "4.1.1.40", "sbo": "SBO:0000176"}, "metabolites": {"gcald_m": 1.0, "h_m": -1.0, "co2_m": 1.0, "hpyr_m": -1.0}, "id": "RM01393", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Histamine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"hista_e": -1.0, "hista_c": 1.0}, "id": "TCE0464", "gene_reaction_rule": ""}, {"subsystem": "Arachidonic acid metabolism", "name": "11,12-EET hydrolase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R07109", "ec-code": "3.3.2.10", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "dhet_c": 1.0, "eet_c": -1.0}, "id": "RC07109", "gene_reaction_rule": "WBGene00010628 or WBGene00019329"}, {"subsystem": "Glycosylphosphatidylinositol(GPI)-anchor biosynthesis", "name": "N-Acetyl-D-glucosaminylphosphatidylinositol acetyhydrolase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R03482", "ec-code": "3.5.1.89", "sbo": "SBO:0000176"}, "metabolites": {"acgpail_c": -1.0, "ac_c": 1.0, "gpail_c": 1.0, "h2o_c": -1.0}, "id": "RC03482", "gene_reaction_rule": "WBGene00013131"}, {"subsystem": "Ubiquinone and other terpenoid-quinone biosynthesis", "name": "4-hydroxyphenyllactate:NAD+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R03336", "ec-code": "1.1.1.237", "sbo": "SBO:0000176"}, "metabolites": {"nad_c": 1.0, "34hpp_c": -1.0, "nadh_c": -1.0, "h_c": -1.0, "34hpl_c": 1.0}, "id": "RC03336", "gene_reaction_rule": ""}, {"subsystem": "Inositol phosphate metabolism", "name": "phosphatidylinositol phospholipase C", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03332", "ec-code": "3.1.4.11", "sbo": "SBO:0000176"}, "metabolites": {"dag_pl_c": 1.0, "h2o_c": -1.0, "mi1p-D_c": 1.0, "h_c": 1.0, "pail_c": -1.0}, "id": "RC03332", "gene_reaction_rule": "WBGene00004036 or WBGene00004037 or WBGene00004038 or WBGene00004039 or WBGene00001177"}, {"subsystem": "Inositol phosphate metabolism", "name": "1D-myo-inositol-3-phosphate lyase (isomerizing)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R07324", "ec-code": "5.5.1.4", "sbo": "SBO:0000176"}, "metabolites": {"mi3p-D_c": 1.0, "g6p-A_c": -1.0}, "id": "RC07324", "gene_reaction_rule": "WBGene00012148"}, {"subsystem": "Pyrimidine metabolism", "name": "pseudouridine synthase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03020", "ec-code": "5.4.99.12", "sbo": "SBO:0000176"}, "metabolites": {"uri_c": -1.0, "psduri_c": 1.0}, "id": "RC03020", "gene_reaction_rule": "WBGene00022250 or WBGene00004248"}, {"subsystem": "Fatty acid metabolism", "name": "Butanoyl-CoA:oxygen 2-oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01175", "ec-code": ["1.3.8.7", "1.3.8.1"], "sbo": "SBO:0000176"}, "metabolites": {"b2coa_m": 1.0, "etfox_m": -1.0, "btcoa_m": -1.0, "etfrd_m": 1.0}, "id": "RM01175", "gene_reaction_rule": "(WBGene00020812 or WBGene00019406 or WBGene00020366) or (WBGene00016943 or WBGene00015894)"}, {"subsystem": "Fatty acid elongation", "name": "butanoyl-CoA:acetyl-CoA C-butanoyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01177", "ec-code": ["2.3.1.16", "2.3.1.9"], "sbo": "SBO:0000176"}, "metabolites": {"accoa_m": 1.0, "3ohcoa_m": -1.0, "coa_m": -1.0, "btcoa_m": 1.0}, "id": "RM01177", "gene_reaction_rule": "(WBGene00015125 or WBGene00009952) or (WBGene00020166 or WBGene00002183)"}, {"subsystem": "Ascaroside biosynthesis", "name": "ascr1 transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"ascr1_c": -1.0, "ascr1_e": 1.0}, "id": "TCE5119", "gene_reaction_rule": ""}, {"subsystem": "Ascaroside biosynthesis", "name": "ascr18 transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"ascr18_e": 1.0, "ascr18_c": -1.0}, "id": "TCE5116", "gene_reaction_rule": ""}, {"subsystem": "Ascaroside biosynthesis", "name": "ascr10 transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"ascr10_e": 1.0, "ascr10_c": -1.0}, "id": "TCE5117", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Uptake of serotonin", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"srtn_c": 1.0, "srtn_e": -1.0}, "id": "TCE5114", "gene_reaction_rule": ""}, {"subsystem": "Glycerolipid metabolism", "name": "1,2-diacyl-sn-glycerol acylhydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R02687", "R05209"], "ec-code": ["3.1.1.3", "3.1.1.79"], "sbo": "SBO:0000176"}, "metabolites": {"mag_c": 1.0, "h2o_c": -1.0, "Rtotal5_c": 1.0, "dag_tag_c": -1.0, "h_c": 1.0}, "id": "RC02687", "gene_reaction_rule": "WBGene00015484 or WBGene00016704"}, {"subsystem": "Transport", "name": "Uptake of dopamine", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dopa_e": -1.0, "dopa_c": 1.0}, "id": "TCE5112", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Secretion of serotonin", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"srtn_c": -1.0, "h2o_c": -1.0, "atp_c": -1.0, "srtn_e": 1.0, "h_c": 1.0, "adp_c": 1.0, "pi_c": 1.0}, "id": "TCE5113", "gene_reaction_rule": "WBGene00000295"}, {"subsystem": "Transport", "name": "Secretion of dopamine", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dopa_e": 1.0, "h2o_c": -1.0, "dopa_c": -1.0, "atp_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "pi_c": 1.0}, "id": "TCE5111", "gene_reaction_rule": "WBGene00000295"}, {"subsystem": "Glycine, serine and threonine metabolism", "name": "L-serine ammonia-lyase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00220", "ec-code": "4.3.1.19", "sbo": "SBO:0000176"}, "metabolites": {"ser-L_c": -1.0, "pyr_c": 1.0, "nh4_c": 1.0}, "id": "RC00220", "gene_reaction_rule": "WBGene00010456 or WBGene00021787"}, {"subsystem": "Propanoate metabolism", "name": "3-hydroxypropionate dehydrogenase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01608", "ec-code": "1.1.1.59", "sbo": "SBO:0000176"}, "metabolites": {"nad_m": -1.0, "msa_m": 1.0, "h_m": 1.0, "nadh_m": 1.0, "3hpp_m": -1.0}, "id": "RM01608", "gene_reaction_rule": "WBGene00012608"}, {"subsystem": "Exchange with the environment", "name": "2-hydroxyglutarate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"2hglut_e": -1.0}, "id": "EX02630", "gene_reaction_rule": ""}, {"subsystem": "Selenocompound metabolism", "name": "S-adenosyl-L-methionine:hydrogen-selenide Se-methyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R09371", "ec-code": "2.1.1.-", "sbo": "SBO:0000176"}, "metabolites": {"metsel_c": 1.0, "amet_c": -1.0, "seln_c": -1.0, "ahcys_c": 1.0, "h_c": 1.0}, "id": "RC09371", "gene_reaction_rule": "WBGene00013151 or WBGene00014228"}, {"subsystem": "Tryptophan metabolism", "name": "Formylkynurenine hydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03936", "ec-code": "3.7.1.3", "sbo": "SBO:0000176"}, "metabolites": {"Lfmkynr_c": -1.0, "nformanth_c": 1.0, "h2o_c": -1.0, "ala-L_c": 1.0, "h_c": 1.0}, "id": "RC03936", "gene_reaction_rule": "WBGene00015802"}, {"subsystem": "Carnitine shuttle", "name": "Carnitine-acylcarnitine translocase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"pcrn_c": -1.0, "pcrn_m": 1.0}, "id": "TCM5029", "gene_reaction_rule": "WBGene00000996 or WBGene00008320"}, {"subsystem": "Aminoacyl-tRNA biosynthesis", "name": "L-Valine:tRNAVal ligase (AMP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03665", "ec-code": "6.1.1.9", "sbo": "SBO:0000176"}, "metabolites": {"ppi_m": 1.0, "atp_m": -1.0, "val-L_m": -1.0, "valtrna_m": 1.0, "trnaval_m": -1.0, "amp_m": 1.0}, "id": "RM03665", "gene_reaction_rule": "WBGene00006935"}, {"subsystem": "Transport", "name": "cysteine transport to mitochondria", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"cys-L_c": -1.0, "cys-L_m": 1.0}, "id": "TCM5027", "gene_reaction_rule": ""}, {"subsystem": "Arachidonic acid metabolism", "name": "11,12-DHET demand", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"dhet_c": -1.0}, "id": "DMN0068", "gene_reaction_rule": ""}, {"subsystem": "Glycolysis / Gluconeogenesis", "name": "ADP:beta-D-glucose 6-phosphotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R09086", "ec-code": "2.7.1.147", "sbo": "SBO:0000176"}, "metabolites": {"h_c": 1.0, "g6p-B_c": 1.0, "glc-D-B_c": -1.0, "adp_c": -1.0, "amp_c": 1.0}, "id": "RC09086", "gene_reaction_rule": "WBGene00016810"}, {"subsystem": "Ascaroside biosynthesis", "name": "ascr-coa (ascr10) hydrolysis", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"ascr10coa_c": -1.0, "coa_c": 1.0, "h2o_c": -1.0, "ascr10_c": 1.0, "h_c": 1.0}, "id": "RCC0229", "gene_reaction_rule": ""}, {"subsystem": "Ascaroside biosynthesis", "name": "ascr-coa (ascr5) hydrolysis", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"h_c": 1.0, "h2o_c": -1.0, "coa_c": 1.0, "ascr5_c": 1.0, "ascr5coa_c": -1.0}, "id": "RCC0228", "gene_reaction_rule": ""}, {"subsystem": "Ascaroside biosynthesis", "name": "very long chain ascaroside ((w-1)-ascr-C27)  synthesis", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"o2_c": -3.0, "h2o_c": 1.0, "nadp_c": 1.0, "nadph_c": -1.0, "26ascfa27p0coa_c": 1.0, "cdp_c": 1.0, "h2o2_c": 1.0, "fa28p0coa_c": -1.0, "co2_c": 1.0, "cdpascl_c": -1.0}, "id": "RCC0227", "gene_reaction_rule": ""}, {"subsystem": "Ascaroside biosynthesis", "name": "ascr10 synthesis", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "ascr18coa_c": -1.0, "accoa_c": 1.0, "h2o_c": -1.0, "h2o2_c": 1.0, "coa_c": -1.0, "h_c": 1.0, "nad_c": -1.0, "ascr10coa_c": 1.0, "nadh_c": 1.0}, "id": "RCC0226", "gene_reaction_rule": "(WBGene00008564 or WBGene00019060 or WBGene00008567) and WBGene00017123 and WBGene00000991 and WBGene00013284"}, {"subsystem": "Arachidonic acid metabolism", "name": "Prostaglandin E2 demand", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"prostge2_c": -1.0}, "id": "DMN0066", "gene_reaction_rule": ""}, {"subsystem": "Arachidonic acid metabolism", "name": "Prostaglandin D2 demand", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"prostgd2_c": -1.0}, "id": "DMN0067", "gene_reaction_rule": ""}, {"subsystem": "Ether lipid metabolism", "name": "2-Acyl-1-(1-alkenyl)-sn-glycero-3-phosphate demand", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"alkenac2gp_c": -1.0}, "id": "DMN0060", "gene_reaction_rule": ""}, {"subsystem": "Ether lipid metabolism", "name": "1-Alkenyl-2-acylglycerol demand", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"alkenac2g_c": -1.0}, "id": "DMN0061", "gene_reaction_rule": ""}, {"subsystem": "Ether lipid metabolism", "name": "1-(1-Alkenyl)-sn-glycerol demand", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"alkenglyc_c": -1.0}, "id": "DMN0062", "gene_reaction_rule": ""}, {"subsystem": "Arachidonic acid metabolism", "name": "w-hydroxyl leukotriene B4 demand", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"leuktrB4woh_c": -1.0}, "id": "DMN0063", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Quinolinate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"quln_m": 1.0, "quln_c": -1.0}, "id": "TCM1042", "gene_reaction_rule": ""}, {"subsystem": "Histidine metabolism", "name": "N-Methylhistamine:oxygen oxidoreductase (deaminating) (copper-containing)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R04674", "ec-code": "1.4.3.4", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "h2o_c": -1.0, "3mldz_c": 1.0, "h2o2_c": 1.0, "mhista_c": -1.0, "nh4_c": 1.0}, "id": "RC04674", "gene_reaction_rule": "WBGene00000138"}, {"subsystem": "Transport", "name": "Methylhistamine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"mhista_c": -1.0, "mhista_e": 1.0}, "id": "TCE7666", "gene_reaction_rule": ""}, {"subsystem": "Alanine, aspartate and glutamate metabolism", "name": "D-Aspartate:oxygen oxidoreductase (deaminating)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00359", "ec-code": "1.4.3.1", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "h2o_c": -1.0, "asp-D_c": -1.0, "h2o2_c": 1.0, "oaa_c": 1.0, "nh4_c": 1.0}, "id": "RC00359", "gene_reaction_rule": "(WBGene00008127 or WBGene00017565 or WBGene00017648)"}, {"subsystem": "Transport", "name": "Isocitrate and Citrate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"cit_m": 1.0, "icit_c": 1.0, "icit_m": -1.0, "cit_c": -1.0}, "id": "TCM1047", "gene_reaction_rule": ""}, {"subsystem": "Ubiquinone and other terpenoid-quinone biosynthesis", "name": "L-tyrosine:2-oxoglutarate aminotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00734", "ec-code": ["2.6.1.1", "2.6.1.5"], "sbo": "SBO:0000176"}, "metabolites": {"tyr-L_m": -1.0, "34hpp_m": 1.0, "glu-L_m": 1.0, "akg_m": -1.0}, "id": "RM00734", "gene_reaction_rule": "WBGene00016652 or WBGene00015778"}, {"subsystem": "Alanine, aspartate and glutamate metabolism", "name": "L-Aspartate:2-oxoglutarate aminotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00355", "ec-code": "2.6.1.1", "sbo": "SBO:0000176"}, "metabolites": {"akg_c": -1.0, "glu-L_c": 1.0, "oaa_c": 1.0, "asp-L_c": -1.0}, "id": "RC00355", "gene_reaction_rule": "WBGene00020146"}, {"subsystem": "Citrate cycle (TCA cycle)", "name": "acetyl-CoA:oxaloacetate C-acetyltransferase [(pro-S)-carboxymethyl-forming, ADP-phosphorylating]", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00352", "ec-code": "2.3.3.8", "sbo": "SBO:0000176"}, "metabolites": {"adp_c": 1.0, "atp_c": -1.0, "cit_c": -1.0, "oaa_c": 1.0, "coa_c": -1.0, "accoa_c": 1.0, "pi_c": 1.0}, "id": "RC00352", "gene_reaction_rule": "WBGene00007150 or WBGene00016995"}, {"subsystem": "Retinol metabolism", "name": "retinol: NADP+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R08379", "ec-code": "1.1.-.-", "sbo": "SBO:0000176"}, "metabolites": {"retinal_c": 1.0, "retinol_c": -1.0, "nadp_c": -1.0, "nadph_c": 1.0, "h_c": 1.0}, "id": "RC08379", "gene_reaction_rule": "(WBGene00010063 or WBGene00000976) or WBGene00007780"}, {"subsystem": "Exchange with the environment", "name": "D-Lactate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"lac-D_e": -1.0}, "id": "EX00256", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "\"3,5-Diiodo-L-tyrosine\" exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"35diotyr_e": -1.0}, "id": "EX01060", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Phosphatidylserine export from mitochondria", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"ps_m": -1.0, "ps_c": 1.0}, "id": "TCM5111", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Deoxyuridine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"duri_e": -1.0, "duri_c": 1.0}, "id": "TCE0573", "gene_reaction_rule": ""}, {"subsystem": "Carnitine shuttle", "name": "Acetyl-CoA:carnitine O-acetyltransferase II", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02396", "ec-code": "2.3.1.7", "sbo": "SBO:0000176"}, "metabolites": {"accoa_m": 1.0, "coa_m": -1.0, "crn_m": 1.0, "acrn_m": -1.0}, "id": "RM02396", "gene_reaction_rule": "WBGene00011122"}, {"subsystem": "Fructose and mannose metabolism", "name": "fucose-1-phosphate guanylyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01951", "ec-code": "2.7.7.30", "sbo": "SBO:0000176"}, "metabolites": {"gdpfuc_c": 1.0, "ppi_c": 1.0, "gtp_c": -1.0, "h_c": -1.0, "fuc1p-L_c": -1.0}, "id": "RC01951", "gene_reaction_rule": "WBGene00044903"}, {"subsystem": "Transport", "name": "L-Ascorbate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"ascb-L_e": -1.0, "ascb-L_c": 1.0}, "id": "TCE0694", "gene_reaction_rule": ""}, {"subsystem": "Tryptophan metabolism", "name": "L-Tryptophan decarboxy-lyase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00685", "ec-code": "4.1.1.28", "sbo": "SBO:0000176"}, "metabolites": {"trypta_c": 1.0, "co2_c": 1.0, "trp-L_c": -1.0, "h_c": -1.0}, "id": "RC00685", "gene_reaction_rule": "WBGene00000239 or WBGene00001839 or WBGene00006562"}, {"subsystem": "Ascaroside biosynthesis", "name": "ascr3 transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"ascr3_e": 1.0, "ascr3_c": -1.0}, "id": "TCE5118", "gene_reaction_rule": ""}, {"subsystem": "Tryptophan metabolism", "name": "L-Kynurenine:2-oxoglutarate aminotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01956", "ec-code": "2.6.1.7", "sbo": "SBO:0000176"}, "metabolites": {"akg_c": -1.0, "glu-L_c": 1.0, "Lkynr_c": -1.0, "4aphdob_c": 1.0}, "id": "RC01956", "gene_reaction_rule": "WBGene00009232"}, {"subsystem": "Tryptophan metabolism", "name": "N-Formyl-L-kynurenine amidohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01959", "ec-code": "3.5.1.9", "sbo": "SBO:0000176"}, "metabolites": {"Lfmkynr_c": -1.0, "h2o_c": -1.0, "Lkynr_c": 1.0, "for_c": 1.0, "h_c": 1.0}, "id": "RC01959", "gene_reaction_rule": "WBGene00017051"}, {"subsystem": "Transport", "name": "iodide transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"i_e": -1.0, "i_c": 1.0}, "id": "TCE5502", "gene_reaction_rule": ""}, {"subsystem": "Propanoate metabolism", "name": "3-Hydroxypropionyl-CoA hydro-lyase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R03045", "ec-code": "4.2.1.17", "sbo": "SBO:0000176"}, "metabolites": {"prpncoa_m": -1.0, "h2o_m": -1.0, "3hpcoa_m": 1.0}, "id": "RM03045", "gene_reaction_rule": "WBGene00001155"}, {"subsystem": "Cysteine and methionine metabolism", "name": "S-adenosyl-L-methionine carboxy-lyase [(5-deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium-forming]", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00178", "ec-code": "4.1.1.50", "sbo": "SBO:0000176"}, "metabolites": {"amet_c": -1.0, "co2_c": 1.0, "h_c": -1.0, "ametam_c": 1.0}, "id": "RC00178", "gene_reaction_rule": "WBGene00004875"}, {"subsystem": "Fructose and mannose metabolism", "name": "GTP:alpha-D-glucose-1-phosphate guanylyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"ec-code": "2.7.7.13", "sbo": "SBO:0000176"}, "metabolites": {"gdpg_c": 1.0, "ppi_c": 1.0, "gtp_c": -1.0, "h_c": -1.0, "g1p_c": -1.0}, "id": "RCC0139", "gene_reaction_rule": "WBGene00016583 or WBGene00021628"}, {"subsystem": "Artificial conversions", "name": "D-Glucose to beta D-Glucose", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"glc-D-B_c": 1.0, "glc-D_c": -1.0}, "id": "RCC0138", "gene_reaction_rule": ""}, {"subsystem": "Pyruvate metabolism", "name": "methylglyoxal synthase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "4.2.3.3", "sbo": "SBO:0000176"}, "metabolites": {"pi_c": 1.0, "g3p_c": -1.0, "mthgxl_c": 1.0}, "id": "RCC0131", "gene_reaction_rule": ""}, {"subsystem": "Fatty acid metabolism", "name": "fatty-acid--CoA ligase (vacc)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00390", "ec-code": "6.2.1.3", "sbo": "SBO:0000176"}, "metabolites": {"atp_c": -1.0, "ppi_c": 1.0, "vacccoa_c": 1.0, "coa_c": -1.0, "amp_c": 1.0, "vacc_c": -1.0}, "id": "RCC0130", "gene_reaction_rule": "WBGene00009221 or WBGene00020343 or WBGene00018152 or WBGene00013575 or WBGene00022037 or WBGene00019920 or WBGene00016716 or WBGene00011173"}, {"subsystem": "Artificial conversions", "name": "D-Glucose to alpha D-Glucose", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"glc-D-A_c": 1.0, "glc-D_c": -1.0}, "id": "RCC0137", "gene_reaction_rule": ""}, {"subsystem": "N-Glycan biosynthesis", "name": "synthesis of peptide with asparagine", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"asn-L_c": -1.0, "Asn-X-Ser/Thr_c": 1.0}, "id": "RCC0136", "gene_reaction_rule": ""}, {"subsystem": "Cysteine and methionine metabolism", "name": "ATP:L-methionine S-adenosyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00177", "ec-code": "2.5.1.6", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "atp_c": -1.0, "ppi_c": 1.0, "amet_c": 1.0, "pi_c": 1.0, "met-L_c": -1.0}, "id": "RC00177", "gene_reaction_rule": "WBGene00008205 or WBGene00015538 or WBGene00015540 or WBGene00006416"}, {"subsystem": "Purine metabolism", "name": "ATP:AMP phosphotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00127", "ec-code": "2.7.4.3", "sbo": "SBO:0000176"}, "metabolites": {"amp_c": -1.0, "atp_c": -1.0, "adp_c": 2.0}, "id": "RC00127", "gene_reaction_rule": "WBGene00008458 or (WBGene00009531 or WBGene00002879)"}, {"subsystem": "Ascaroside biosynthesis", "name": "ascr5 transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"ascr5_e": 1.0, "ascr5_c": -1.0}, "id": "TCE5115", "gene_reaction_rule": ""}, {"subsystem": "Nicotinate and nicotinamide metabolism", "name": "Nicotinate D-ribonucleotide phosphohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03346", "ec-code": "3.1.3.5", "sbo": "SBO:0000176"}, "metabolites": {"nicrnt_c": -1.0, "h2o_c": -1.0, "nicrns_c": 1.0, "pi_c": 1.0}, "id": "RC03346", "gene_reaction_rule": "WBGene00017775 or WBGene00012423 or WBGene00022201"}, {"subsystem": "Tyrosine metabolism (indirect)", "name": "NADP+:L-tyrosine oxidoreductase (iodinating)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R10059", "ec-code": "1.22.1.1", "sbo": "SBO:0000176"}, "metabolites": {"nadph_c": 2.0, "nadp_c": -2.0, "i_c": -2.0, "35diotyr_c": 1.0, "tyr-L_c": -1.0}, "id": "RC10059", "gene_reaction_rule": "WBGene00015334"}, {"subsystem": "Exchange with the environment", "name": "Retinal exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"retinal_e": -1.0}, "id": "EX00376", "gene_reaction_rule": ""}, {"subsystem": "Sphingolipid metabolism", "name": "acyl-CoA:sphingosine N-acyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R06517", "ec-code": "2.3.1.24", "sbo": "SBO:0000176"}, "metabolites": {"Rtotalcoa_c": -1.0, "sphgn_ce_c": -1.0, "coa_c": 1.0, "h_c": 1.0, "dhcrm_ce_c": 1.0}, "id": "RC06517", "gene_reaction_rule": "WBGene00002043 or WBGene00002044 or WBGene00006505"}, {"subsystem": "Sphingolipid metabolism", "name": "N-acylsphingosine amidohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R06518", "ec-code": "3.5.1.23", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "sphgn_ce_c": 1.0, "Rtotal_c": 1.0, "dhcrm_ce_c": -1.0}, "id": "RC06518", "gene_reaction_rule": "WBGene00020947"}, {"subsystem": "Sphingolipid metabolism", "name": "sphingolipid delta-4 desaturase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R06519", "ec-code": "1.14.-.-", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "h2o_c": 2.0, "nadp_c": 1.0, "nadph_c": -1.0, "crm_ce_c": 1.0, "h_c": -1.0, "dhcrm_ce_c": -1.0}, "id": "RC06519", "gene_reaction_rule": "WBGene00017996 or WBGene00013197"}, {"subsystem": "Starch and sucrose metabolism", "name": "dextrin phosphorylase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "2.4.1.1", "sbo": "SBO:0000176"}, "metabolites": {"dxtrn3_c": -1.0, "pi_c": -1.0, "g1p_c": 1.0}, "id": "RCC0046", "gene_reaction_rule": "WBGene00020696"}, {"subsystem": "Starch and sucrose metabolism", "name": "Dextrin 6-alpha-D-glucanohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "3.2.1.33", "sbo": "SBO:0000176"}, "metabolites": {"dxtrn2_c": -1.0, "dxtrn3_c": 0.8, "h2o_c": -0.2, "glc-D-B_c": 0.2}, "id": "RCC0045", "gene_reaction_rule": "WBGene00011050"}, {"subsystem": "Starch and sucrose metabolism", "name": "dextrin transglycosylase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "2.4.1.25", "sbo": "SBO:0000176"}, "metabolites": {"dxtrn2_c": 1.0, "dxtrn1_c": -1.0}, "id": "RCC0044", "gene_reaction_rule": "WBGene00011050"}, {"subsystem": "Starch and sucrose metabolism", "name": "glycogen phosphorylase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01821", "ec-code": "2.4.1.1", "sbo": "SBO:0000176"}, "metabolites": {"dxtrn1_c": 0.5, "pi_c": -0.5, "glycogen_c": -1.0, "g1p_c": 0.5}, "id": "RCC0043", "gene_reaction_rule": "WBGene00020696"}, {"subsystem": "N-Glycan biosynthesis", "name": "beta-N-acetylglucosaminidase (acting on fnm2masn)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "3.2.1.52", "sbo": "SBO:0000176"}, "metabolites": {"acgam_c": 1.0, "h2o_c": -1.0, "fnm2masn_c": -1.0, "fm2masn_c": 1.0}, "id": "RCC0042", "gene_reaction_rule": "WBGene00015767 or WBGene00012663 or WBGene00021766 or WBGene00013497"}, {"subsystem": "N-Glycan biosynthesis", "name": "beta-N-acetylglucosaminidase (acting on nm2masn)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "3.2.1.52", "sbo": "SBO:0000176"}, "metabolites": {"acgam_c": 1.0, "h2o_c": -1.0, "nm2masn_c": -1.0, "m2masn_c": 1.0}, "id": "RCC0041", "gene_reaction_rule": "WBGene00015767 or WBGene00012663 or WBGene00021766 or WBGene00013497"}, {"subsystem": "N-Glycan biosynthesis", "name": "beta-N-acetylglucosaminidase (acting on nm3masn)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "3.2.1.52", "sbo": "SBO:0000176"}, "metabolites": {"nm3masn_c": -1.0, "acgam_c": 1.0, "h2o_c": -1.0, "m3masn_c": 1.0}, "id": "RCC0040", "gene_reaction_rule": "WBGene00015767 or WBGene00012663 or WBGene00021766 or WBGene00013497"}, {"subsystem": "Ubiquinone and other terpenoid-quinone biosynthesis", "name": "4-hydroxybenzoyl-CoA formation", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R08767", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "nad_c": -1.0, "4cmcoa_c": -1.0, "coa_c": -1.0, "h_c": 1.0, "accoa_c": 1.0, "4hbzcoa_c": 1.0, "nadh_c": 1.0}, "id": "RC08767", "gene_reaction_rule": ""}, {"subsystem": "Ubiquinone and other terpenoid-quinone biosynthesis", "name": "3-(4-hydroxyphenyl)lactate hydro-lyase (4-coumarate-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R08766", "ec-code": "4.2.1.-", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": 1.0, "T4hcinnm_c": 1.0, "34hpl_c": -1.0}, "id": "RC08766", "gene_reaction_rule": ""}, {"subsystem": "Primary bile acid biosynthesis", "name": "3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate,NADPH:oxygen oxidoreductase (26-hydroxylating)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R08761", "ec-code": "1.14.13.15", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "h2o_c": 1.0, "nadp_c": 1.0, "nadph_c": -1.0, "thcholstoic_c": 1.0, "thcholst_c": -1.0}, "id": "RC08761", "gene_reaction_rule": "WBGene00000905"}, {"subsystem": "Glycerophospholipid metabolism", "name": "Phosphatidylcholine 2-acylhydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01315", "ec-code": "3.1.1.4", "sbo": "SBO:0000176"}, "metabolites": {"pchol_c": -1.0, "h2o_c": -1.0, "h_c": 1.0, "lpchol_c": 1.0, "Rtotal2_c": 1.0}, "id": "RC01315", "gene_reaction_rule": "WBGene00019747 or WBGene00009801 or WBGene00012319 or WBGene00017026 or WBGene00019229 or WBGene00022233 or WBGene00011423 or WBGene00007419 or WBGene00044468"}, {"subsystem": "Pyrimidine metabolism", "name": "hydrogen-carbonate:L-glutamine amido-ligase (ADP-forming, carbamate-phosphorylating)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00575", "ec-code": "6.3.5.5", "sbo": "SBO:0000176"}, "metabolites": {"cbp_c": 1.0, "atp_c": -2.0, "gln-L_c": -1.0, "glu-L_c": 1.0, "hco3_c": -1.0, "h2o_c": -1.0, "h_c": 2.0, "adp_c": 2.0, "pi_c": 1.0}, "id": "RC00575", "gene_reaction_rule": "WBGene00004259"}, {"subsystem": "Pyrimidine metabolism", "name": "ATP:CDP phosphotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00570", "ec-code": "2.7.4.6", "sbo": "SBO:0000176"}, "metabolites": {"cdp_c": -1.0, "ctp_c": 1.0, "adp_c": 1.0, "atp_c": -1.0}, "id": "RC00570", "gene_reaction_rule": "WBGene00019899 or WBGene00021692 or WBGene00009119"}, {"subsystem": "Pyrimidine metabolism", "name": "UTP:ammonia ligase (ADP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00571", "ec-code": "6.3.4.2", "sbo": "SBO:0000176"}, "metabolites": {"utp_c": -1.0, "atp_c": -1.0, "h_c": 2.0, "adp_c": 1.0, "ctp_c": 1.0, "pi_c": 1.0, "nh4_c": -1.0}, "id": "RC00571", "gene_reaction_rule": "WBGene00012316"}, {"subsystem": "Transport", "name": "Ethanol transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"etoh_m": 1.0, "etoh_c": -1.0}, "id": "TCM1048", "gene_reaction_rule": ""}, {"subsystem": "Pyrimidine metabolism", "name": "UTP:L-glutamine amido-ligase (ADP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00573", "ec-code": "6.3.4.2", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "atp_c": -1.0, "gln-L_c": -1.0, "glu-L_c": 1.0, "utp_c": -1.0, "h_c": 2.0, "adp_c": 1.0, "ctp_c": 1.0, "pi_c": 1.0}, "id": "RC00573", "gene_reaction_rule": "WBGene00012316"}, {"subsystem": "Purine metabolism", "name": "N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01083", "ec-code": "4.3.2.2", "sbo": "SBO:0000176"}, "metabolites": {"fum_c": 1.0, "amp_c": 1.0, "dcamp_c": -1.0}, "id": "RC01083", "gene_reaction_rule": "WBGene00011064"}, {"subsystem": "Citrate cycle (TCA cycle)", "name": "(S)-malate hydro-lyase (fumarate-forming) (cytosolic)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01082", "ec-code": "4.2.1.2", "sbo": "SBO:0000176"}, "metabolites": {"mal-L_c": -1.0, "h2o_c": 1.0, "fum_c": 1.0}, "id": "RC01082", "gene_reaction_rule": "WBGene00001503"}, {"subsystem": "Alanine, aspartate and glutamate metabolism", "name": "L-aspartate:L-glutamine amido-ligase (AMP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00578", "ec-code": "6.3.5.4", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "atp_c": -1.0, "gln-L_c": -1.0, "asn-L_c": 1.0, "ppi_c": 1.0, "glu-L_c": 1.0, "amp_c": 1.0, "asp-L_c": -1.0, "h_c": 1.0}, "id": "RC00578", "gene_reaction_rule": "WBGene00003816 or WBGene00019730"}, {"subsystem": "Carnitine shuttle", "name": "Carnitine-acylcarnitine translocase (tmndnccrn)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"tmndnccrn_c": -1.0, "tmndnccrn_m": 1.0}, "id": "TCM5056", "gene_reaction_rule": "WBGene00000996 or WBGene00008320"}, {"subsystem": "Exchange with the environment", "name": "\"5,10-Methylenetetrahydrofolate\" exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"mlthf_e": -1.0}, "id": "EX00143", "gene_reaction_rule": ""}, {"subsystem": "Miscellaneous", "name": "Forssman hapten demand", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"forssman_ce_c": -1.0}, "id": "DMN1005", "gene_reaction_rule": ""}, {"subsystem": "Inositol phosphate metabolism", "name": "Inositol 1,3,4,5,6-pentakisphosphate demand.", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"mi13456p_c": -1.0}, "id": "DMN1004", "gene_reaction_rule": ""}, {"subsystem": "Inositol phosphate metabolism", "name": "Inositol 1,3,4-trisphosphate demand", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"mi134p_c": -1.0}, "id": "DMN1007", "gene_reaction_rule": ""}, {"subsystem": "Glycosylphosphatidylinositol(GPI)-anchor biosynthesis", "name": "D-Glucosaminylphosphatidylinositol demand", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"gpail_c": -1.0}, "id": "DMN1006", "gene_reaction_rule": ""}, {"subsystem": "Miscellaneous", "name": "Diiodotyrosine demand", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"35diotyr_c": -1.0}, "id": "DMN1001", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Indole-3-acetate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"ind3ac_e": -1.0}, "id": "EX00954", "gene_reaction_rule": ""}, {"subsystem": "Carnitine shuttle", "name": "Carnitine-acylcarnitine translocase (lnlccrn)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"lnlccrn_c": -1.0, "lnlccrn_m": 1.0}, "id": "TCM5053", "gene_reaction_rule": "WBGene00000996 or WBGene00008320"}, {"subsystem": "Exchange with the environment", "name": "L-2-Aminoadipate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"L2aadp_e": -1.0}, "id": "EX00956", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Tyramine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"tym_e": -1.0}, "id": "EX00483", "gene_reaction_rule": ""}, {"subsystem": "Carnitine shuttle", "name": "Carnitine-acylcarnitine translocase (fa8p1n3crn)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"fa8p1n3crn_c": -1.0, "fa8p1n3crn_m": 1.0}, "id": "TCM5052", "gene_reaction_rule": "WBGene00000996 or WBGene00008320"}, {"subsystem": "Purine metabolism", "name": "Guanosine 5-monophosphate phosphohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01227", "ec-code": "3.1.3.5", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "gmp_c": -1.0, "pi_c": 1.0, "gsn_c": 1.0}, "id": "RC01227", "gene_reaction_rule": "WBGene00017775 or WBGene00012423 or WBGene00022201"}, {"subsystem": "Riboflavin metabolism", "name": "ATP:FMN adenylyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00161", "ec-code": "2.7.7.2", "sbo": "SBO:0000176"}, "metabolites": {"fad_c": 1.0, "ppi_c": 1.0, "fmn_c": -1.0, "h_c": -1.0, "atp_c": -1.0}, "id": "RC00161", "gene_reaction_rule": "WBGene00011271"}, {"subsystem": "One carbon pool by folate", "name": "5-methyltetrahydrofolate:NADP+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01224", "ec-code": "1.5.1.20", "sbo": "SBO:0000176"}, "metabolites": {"nadp_c": 1.0, "nadph_c": -1.0, "h_c": -2.0, "mlthf_c": -1.0, "5mthf_c": 1.0}, "id": "RC01224", "gene_reaction_rule": "WBGene00015512"}, {"subsystem": "One carbon pool by folate", "name": "5,10-methylenetetrahydrofolate:NADP+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01220", "ec-code": "1.5.1.5", "sbo": "SBO:0000176"}, "metabolites": {"nadp_c": -1.0, "nadph_c": 1.0, "methf_c": 1.0, "mlthf_c": -1.0}, "id": "RC01220", "gene_reaction_rule": "WBGene00019492"}, {"subsystem": "Carnitine shuttle", "name": "Carnitine-acylcarnitine translocase (dlnlcgcrn)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dlnlcgcrn_c": -1.0, "dlnlcgcrn_m": 1.0}, "id": "TCM5050", "gene_reaction_rule": "WBGene00000996 or WBGene00008320"}, {"subsystem": "Transport", "name": "octopamine secretion", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"octpmn_e": 1.0, "octpmn_c": -1.0}, "id": "TCE5094", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Hydrogen cyanide exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"cyan_e": -1.0}, "id": "EX01326", "gene_reaction_rule": ""}, {"subsystem": "Purine metabolism", "name": "GMP:diphosphate 5-phospho-alpha-D-ribosyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01229", "ec-code": ["2.4.2.7", "2.4.2.8"], "sbo": "SBO:0000176"}, "metabolites": {"gua_c": -1.0, "gmp_c": 1.0, "ppi_c": 1.0, "prpp_c": -1.0}, "id": "RC01229", "gene_reaction_rule": "WBGene00020557 or WBGene00013690"}, {"subsystem": "Glyoxylate and dicarboxylate metabolism", "name": "malate synthase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00472", "ec-code": "2.3.3.9", "sbo": "SBO:0000176"}, "metabolites": {"mal-L_m": 1.0, "h2o_m": -1.0, "accoa_m": -1.0, "glx_m": -1.0, "h_m": 1.0, "coa_m": 1.0}, "id": "RM00472", "gene_reaction_rule": "WBGene00001564"}, {"subsystem": "Exchange with the environment", "name": "ATP exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"atp_e": -1.0}, "id": "EX00002", "gene_reaction_rule": ""}, {"subsystem": "Phenylalanine metabolism", "name": "L-Phenylalanine,tetrahydrobiopterin:oxygen oxidoreductase (4-hydroxylating)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01795", "ec-code": "1.14.16.1", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "h2o_c": 1.0, "thbpt_c": -1.0, "tyr-L_c": 1.0, "dhbpt_c": 1.0, "phe-L_c": -1.0}, "id": "RC01795", "gene_reaction_rule": "WBGene00000240"}, {"subsystem": "Folate biosynthesis", "name": "5,6,7,8-tetrahydrobiopterin:NADP+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01794", "ec-code": "1.5.1.34", "sbo": "SBO:0000176"}, "metabolites": {"thbpt_c": 1.0, "nadp_c": 1.0, "nadph_c": -1.0, "h_c": -1.0, "dhbpt_c": -1.0}, "id": "RC01794", "gene_reaction_rule": "WBGene00011398"}, {"subsystem": "Folate biosynthesis", "name": "5,6,7,8-tetrahydrobiopterin:NAD+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01793", "ec-code": "1.5.1.34", "sbo": "SBO:0000176"}, "metabolites": {"thbpt_c": 1.0, "nadh_c": -1.0, "h_c": -1.0, "nad_c": 1.0, "dhbpt_c": -1.0}, "id": "RC01793", "gene_reaction_rule": "WBGene00011398"}, {"subsystem": "Exchange with the environment", "name": "O2 exchange", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"o2_e": -1.0}, "id": "EX00007", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Deoxyadenosine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"dad-2_e": -1.0}, "id": "EX00559", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Phosphate exchange", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"pi_e": -1.0}, "id": "EX00009", "gene_reaction_rule": ""}, {"subsystem": "Glycerophospholipid metabolism", "name": "CTP:phosphatidate cytidyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01799", "ec-code": "2.7.7.41", "sbo": "SBO:0000176"}, "metabolites": {"ctp_c": -1.0, "pa_pl_c": -1.0, "ppi_c": 1.0, "h_c": -1.0, "cdpdag_c": 1.0}, "id": "RC01799", "gene_reaction_rule": "WBGene00016384"}, {"subsystem": "Exchange with the environment", "name": "D-Sorbitol exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"sbt-D_e": -1.0}, "id": "EX00794", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "dADP and dCDP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dadp_c": -1.0, "dadp_m": 1.0, "dcdp_c": 1.0, "dcdp_m": -1.0}, "id": "TCM0222", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "dUTP and dGDP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dgdp_c": 1.0, "dgdp_m": -1.0, "dutp_m": 1.0, "dutp_c": -1.0}, "id": "TCM0221", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "dATP and dCDP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"datp_c": -1.0, "datp_m": 1.0, "dcdp_c": 1.0, "dcdp_m": -1.0}, "id": "TCM0220", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "(S)-3-Hydroxybutanoate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"S3hb_c": -1.0, "S3hb_m": 1.0}, "id": "TCM0224", "gene_reaction_rule": ""}, {"subsystem": "Valine, leucine and isoleucine degradation", "name": "3-Methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R04138", "ec-code": "6.4.1.4", "sbo": "SBO:0000176"}, "metabolites": {"3mgcoa_m": 1.0, "hco3_m": -1.0, "atp_m": -1.0, "3mb2coa_m": -1.0, "pi_m": 1.0, "adp_m": 1.0, "h_m": 1.0}, "id": "RM04138", "gene_reaction_rule": "WBGene00009319 and WBGene00008514"}, {"subsystem": "Transport", "name": "Melibiose transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"melib_c": 1.0, "melib_e": -1.0}, "id": "TCE1130", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Mixed transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"h2o_c": -1.0, "h_e": 1.0, "adp_c": 1.0, "atp_c": -1.0, "pi_c": 1.0}, "id": "TCE1132", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "\"Adenosine 3',5'-bisphosphate\" transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"pap_e": -1.0, "pap_c": 1.0}, "id": "TCE1133", "gene_reaction_rule": ""}, {"subsystem": "Propanoate metabolism", "name": "Acyl-CoA hydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00383", "ec-code": "3.1.2.18", "sbo": "SBO:0000176"}, "metabolites": {"ppcoa_m": -1.0, "ppa_m": 1.0, "coa_m": 1.0, "h_m": 1.0, "h2o_m": -1.0}, "id": "RM00383", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "L-Serine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"ser-L_c": -1.0, "ser-L_m": 1.0}, "id": "TCM1085", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "dUDP and dCTP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dctp_m": 1.0, "dudp_m": -1.0, "dudp_c": 1.0, "dctp_c": -1.0}, "id": "TCM0137", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "L-Valine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"val-L_m": 1.0, "val-L_c": -1.0}, "id": "TCM0135", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Formaldehyde transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"fald_m": -1.0, "fald_c": 1.0}, "id": "TCM0134", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "L-Isoleucine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"ile-L_m": 1.0, "ile-L_c": -1.0}, "id": "TCM0132", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "dTTP and dUDP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dttp_m": 1.0, "dudp_m": -1.0, "dttp_c": -1.0, "dudp_c": 1.0}, "id": "TCM0131", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "dADP and dATP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"datp_c": -1.0, "datp_m": 1.0, "dadp_c": 1.0, "dadp_m": -1.0}, "id": "TCM0130", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Sulfite and Fumarate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"so3_c": 1.0, "fum_c": -1.0, "so3_m": -1.0, "fum_m": 1.0}, "id": "TCM0139", "gene_reaction_rule": ""}, {"subsystem": "Mitochondrial fatty acid beta oxidation", "name": "Beta oxidation of oleic acid (mitochondrial)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R00392", "R02685", "R01778", "R00391"], "ec-code": ["1.3.8.7", "4.2.1.17", "1.1.1.211", "1.1.1.35", "2.3.1.16"], "sbo": "SBO:0000176"}, "metabolites": {"fa16p1n7coa_m": 1.0, "h2o_m": -1.0, "odecoa_m": -1.0, "fad_m": -1.0, "accoa_m": 1.0, "nadh_m": 1.0, "nad_m": -1.0, "coa_m": -1.0, "h_m": 1.0, "fadh2_m": 1.0}, "id": "RMC0089", "gene_reaction_rule": "(WBGene00020812 or WBGene00019406 or WBGene00020366 or WBGene00017125) and ((WBGene00001155 or WBGene00001156) or (WBGene00020347 or WBGene00001150) or WBGene00001152) and ((WBGene00020347 or WBGene00001150) or (WBGene00007129 or WBGene00010035 or WBGene00001157 or WBGene00001158 or WBGene00019978)) and (WBGene00015125 or WBGene00009952)"}, {"subsystem": "Mitochondrial fatty acid beta oxidation", "name": "Beta oxidation of palmitoleic acid (mitochondrial)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R00392", "R02685", "R01778", "R00391"], "ec-code": ["1.3.8.7", "5.3.3.8", "4.2.1.17", "1.1.1.211", "1.1.1.35", "2.3.1.16"], "sbo": "SBO:0000176"}, "metabolites": {"h_m": 4.0, "h2o_m": -4.0, "fad_m": -3.0, "fa16p1n7coa_m": -1.0, "occoa_m": 1.0, "nadh_m": 4.0, "nad_m": -4.0, "coa_m": -4.0, "accoa_m": 4.0, "fadh2_m": 3.0}, "id": "RMC0088", "gene_reaction_rule": "(WBGene00020812 or WBGene00019406 or WBGene00020366 or WBGene00017125) and (WBGene00001153 or WBGene00007130) and ((WBGene00001155 or WBGene00001156) or (WBGene00020347 or WBGene00001150) or WBGene00001152) and ((WBGene00020347 or WBGene00001150) or (WBGene00007129 or WBGene00010035 or WBGene00001157 or WBGene00001158 or WBGene00019978)) and (WBGene00015125 or WBGene00009952)"}, {"subsystem": "Carnitine shuttle", "name": "Acyl-CoA:L-carnitine O-acyltransferase II (Octanoyl-CoA)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "2.3.1.21", "sbo": "SBO:0000176"}, "metabolites": {"coa_m": -1.0, "occoa_m": 1.0, "occrn_m": -1.0, "crn_m": 1.0}, "id": "RMC0087", "gene_reaction_rule": "WBGene00011122"}, {"subsystem": "Transport", "name": "Sodium transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"na1_c": 1.0, "na1_e": -1.0}, "id": "TCE0662", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Methylglyoxal transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"mthgxl_e": 1.0, "mthgxl_c": -1.0}, "id": "TCE0660", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "L-Allo-threonine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"athr-L_e": -1.0}, "id": "EX05519", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Phosphatidylinositol exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"pail_e": -1.0}, "id": "EX01194", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Selenite exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"selnt_e": -1.0}, "id": "EX05684", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Thiocyanate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"tcynt_e": -1.0}, "id": "EX01755", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "D-3-Amino-isobutanoate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"3aib-D_e": -1.0}, "id": "EX01205", "gene_reaction_rule": ""}, {"subsystem": "Glycine, serine and threonine metabolism", "name": "aminoacetone:oxygen oxidoreductase (deaminating)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02529", "ec-code": "1.4.3.4", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "h2o_c": -1.0, "aact_c": -1.0, "h2o2_c": 1.0, "mthgxl_c": 1.0, "nh4_c": 1.0}, "id": "RC02529", "gene_reaction_rule": "WBGene00000138"}, {"subsystem": "Glycerophospholipid metabolism", "name": "CTP:ethanolamine-phosphate cytidylyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R02038", "ec-code": "2.7.7.14", "sbo": "SBO:0000176"}, "metabolites": {"ctp_c": -1.0, "cdpea_c": 1.0, "ppi_c": 1.0, "h_c": -1.0, "ethamp_c": -1.0}, "id": "RC02038", "gene_reaction_rule": "WBGene00016531 or WBGene00021352"}, {"subsystem": "Ubiquinone and other terpenoid-quinone biosynthesis", "name": "4-Hydroxyphenylpyruvate:oxygen oxidoreductase (hydroxylating,decarboxylating)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02521", "ec-code": "1.13.11.27", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "34hpp_c": -1.0, "co2_c": 1.0, "hgentis_c": 1.0}, "id": "RC02521", "gene_reaction_rule": "WBGene00016294 or WBGene00001993"}, {"subsystem": "Glycerophospholipid metabolism", "name": "CDP-diacylglycerol:phosphatidylglycerol 3-phosphatidyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R02030", "ec-code": "2.7.8.-", "sbo": "SBO:0000176"}, "metabolites": {"cmp_c": 1.0, "clpn_c": 1.0, "pglyc_c": -1.0, "h_c": 1.0, "cdpdag_c": -1.0}, "id": "RC02030", "gene_reaction_rule": "WBGene00017763"}, {"subsystem": "Glycerophospholipid metabolism", "name": "S-Adenosyl-L-methionine:ethanolamine-phosphate N-methyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02037", "ec-code": "2.1.1.103", "sbo": "SBO:0000176"}, "metabolites": {"h_c": 1.0, "amet_c": -1.0, "ahcys_c": 1.0, "methamp_c": 1.0, "ethamp_c": -1.0}, "id": "RC02037", "gene_reaction_rule": "WBGene00022781"}, {"subsystem": "Pentose phosphate pathway", "name": "6-Phospho-D-glucono-1,5-lactone lactonohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02035", "ec-code": "3.1.1.31", "sbo": "SBO:0000176"}, "metabolites": {"6pgc_c": 1.0, "h2o_c": -1.0, "6pgl_c": -1.0, "h_c": 1.0}, "id": "RC02035", "gene_reaction_rule": "WBGene00013301"}, {"subsystem": "Exchange with the environment", "name": "Acetylcholine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"ach_e": -1.0}, "id": "EX01996", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Release of molybdate", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"mobd_e": 1.0, "mobd_c": -1.0}, "id": "TCE5099", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "D-aspartate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"asp-D_e": 1.0, "asp-D_c": -1.0}, "id": "TCE5098", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "\"7-alpha,27-Dihydroxycholesterol\" exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"xoltri27_e": -1.0}, "id": "EX06341", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "3-Hydroxyanthranilate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"3hanthrn_c": 1.0, "3hanthrn_e": -1.0}, "id": "TCE5349", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Orotate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"orot_e": -1.0, "orot_c": 1.0}, "id": "TCE5348", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "2-Oxoadipate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"akg_c": 1.0, "2oxoadp_e": 1.0, "2oxoadp_c": -1.0, "akg_e": -1.0}, "id": "TCE5347", "gene_reaction_rule": ""}, {"subsystem": "Pyrimidine metabolism", "name": "ATP:dCDP phosphotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R02326", "ec-code": "2.7.4.6", "sbo": "SBO:0000176"}, "metabolites": {"dctp_c": 1.0, "adp_c": 1.0, "atp_c": -1.0, "dcdp_c": -1.0}, "id": "RC02326", "gene_reaction_rule": "WBGene00019899 or WBGene00021692 or WBGene00009119"}, {"subsystem": "Transport", "name": "Tryptamine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"trypta_c": -1.0, "trypta_e": 1.0}, "id": "TCE5345", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "trans-4-Hydroxycinnamate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"oh1_c": 1.0, "T4hcinnm_e": 1.0, "T4hcinnm_c": -1.0, "oh1_e": -1.0}, "id": "TCE5344", "gene_reaction_rule": ""}, {"subsystem": "Nicotinate and nicotinamide metabolism", "name": "Nicotinamide ribonucleotide phosphohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02323", "ec-code": "3.1.3.5", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "pi_c": 1.0, "nmn_c": -1.0, "rnam_c": 1.0}, "id": "RC02323", "gene_reaction_rule": "WBGene00017775 or WBGene00012423 or WBGene00022201"}, {"subsystem": "Transport", "name": "Phosphoenolpyruvate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"pep_c": -1.0, "hco3_c": 1.0, "pep_e": 1.0, "hco3_e": -1.0}, "id": "TCE5342", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Quinolinate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"so4_c": -1.0, "quln_e": -1.0, "quln_c": 1.0, "so4_e": 1.0}, "id": "TCE5341", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Homogentisate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"hgentis_c": -1.0, "hgentis_e": 1.0}, "id": "TCE5340", "gene_reaction_rule": ""}, {"subsystem": "Purine metabolism", "name": "guanosine:phosphate alpha-D-ribosyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R02147", "ec-code": "2.4.2.1", "sbo": "SBO:0000176"}, "metabolites": {"gua_c": 1.0, "pi_c": -1.0, "r1p_c": 1.0, "gsn_c": -1.0}, "id": "RC02147", "gene_reaction_rule": "WBGene00019298"}, {"subsystem": "Pyrimidine metabolism", "name": "hydrogen-carbonate:ammonia amido-ligase (ADP-forming, carbamate-phosphorylating)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R07641", "ec-code": "6.3.5.5", "sbo": "SBO:0000176"}, "metabolites": {"cbp_c": 1.0, "atp_c": -2.0, "hco3_c": -1.0, "h_c": 2.0, "adp_c": 2.0, "pi_c": 1.0, "nh4_c": -1.0}, "id": "RC07641", "gene_reaction_rule": "WBGene00004259"}, {"subsystem": "Purine metabolism", "name": "XMP:pyrophosphate phosphoribosyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02142", "ec-code": "2.4.2.8", "sbo": "SBO:0000176"}, "metabolites": {"xmp_c": 1.0, "ppi_c": 1.0, "xan_c": -1.0, "prpp_c": -1.0}, "id": "RC02142", "gene_reaction_rule": "WBGene00013690"}, {"subsystem": "Transport", "name": "Pyridoxal transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"pydx_e": -1.0, "pydx_c": 1.0}, "id": "TCE0450", "gene_reaction_rule": ""}, {"subsystem": "Glycolysis / Gluconeogenesis", "name": "beta-D-Glucose 6-phosphate ketol-isomerase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R03321", "ec-code": "5.3.1.9", "sbo": "SBO:0000176"}, "metabolites": {"g6p-B_c": -1.0, "f6p_c": 1.0}, "id": "RC03321", "gene_reaction_rule": "WBGene00013597"}, {"subsystem": "Transport", "name": "7alpha,12alpha-Dihydroxycholest-4-en-3-one transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"h2o_c": -1.0, "atp_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "xoldiolone_c": -1.0, "pi_c": 1.0, "xoldiolone_e": 1.0}, "id": "TCE5307", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "5alpha-Dihydrotestosterone exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"5adtststerone_e": -1.0}, "id": "EX03917", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "5,10-Methylenetetrahydrofolate secretion", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"mlthf_e": 1.0, "h2o_c": -1.0, "atp_c": -1.0, "mlthf_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "pi_c": 1.0}, "id": "TCE5304", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "L-3-Amino-isobutanoate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"3aib_e": -1.0}, "id": "EX03284", "gene_reaction_rule": ""}, {"subsystem": "Aminoacyl-tRNA biosynthesis", "name": "L-Alanine:tRNA(Ala) ligase (AMP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03038", "ec-code": "6.1.1.7", "sbo": "SBO:0000176"}, "metabolites": {"trnaala_c": -1.0, "atp_c": -1.0, "ala-L_c": -1.0, "amp_c": 1.0, "alatrna_c": 1.0, "ppi_c": 1.0}, "id": "RC03038", "gene_reaction_rule": "WBGene00000197"}, {"subsystem": "Transport", "name": "androsterone glucuronide transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"h2o_c": -1.0, "atp_c": -1.0, "andrstrnglc_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "andrstrnglc_e": 1.0, "pi_c": 1.0}, "id": "TCE0401", "gene_reaction_rule": ""}, {"subsystem": "Ubiquinone and other terpenoid-quinone biosynthesis", "name": "4-Coumarate:CoA ligase (AMP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01616", "ec-code": "6.2.1.12", "sbo": "SBO:0000176"}, "metabolites": {"T4hcinnm_m": -1.0, "ppi_m": 1.0, "4cmcoa_m": 1.0, "atp_m": -1.0, "coa_m": -1.0, "amp_m": 1.0}, "id": "RM01616", "gene_reaction_rule": "WBGene00022849"}, {"subsystem": "Purine metabolism", "name": "2-(Formamido)-N1-(5-phosphoribosyl)acetamidine cyclo-ligase (ADP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R04208", "ec-code": "6.3.3.1", "sbo": "SBO:0000176"}, "metabolites": {"atp_c": -1.0, "fpram_c": -1.0, "h_c": 2.0, "adp_c": 1.0, "air_c": 1.0, "pi_c": 1.0}, "id": "RC04208", "gene_reaction_rule": "WBGene00018174"}, {"subsystem": "Purine metabolism", "name": "1-(5-phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate carboxy-lyase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R04209", "ec-code": "4.1.1.21", "sbo": "SBO:0000176"}, "metabolites": {"co2_c": -1.0, "5aizc_c": 1.0, "h_c": 1.0, "air_c": -1.0}, "id": "RC04209", "gene_reaction_rule": "WBGene00015116"}, {"subsystem": "Pyrimidine metabolism", "name": "Uridine 5-monophosphate phosphohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00963", "ec-code": "3.1.3.5", "sbo": "SBO:0000176"}, "metabolites": {"ump_c": -1.0, "h2o_c": -1.0, "pi_c": 1.0, "uri_c": 1.0}, "id": "RC00963", "gene_reaction_rule": "WBGene00017775 or WBGene00012423 or WBGene00022201"}, {"subsystem": "Purine metabolism", "name": "IDP phosphohydrolase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00961", "ec-code": "3.6.1.6", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "pi_c": 1.0, "h_c": 1.0, "idp_c": -1.0, "imp_c": 1.0}, "id": "RC00961", "gene_reaction_rule": "(WBGene00044355 or WBGene00017244) or WBGene00003254 or WBGene00010697"}, {"subsystem": "Protein modification by hydroxylation", "name": "Peptide-L-aspartate,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R04073", "ec-code": "1.14.11.16", "sbo": "SBO:0000176"}, "metabolites": {"akg_c": -1.0, "o2_c": -1.0, "pepasp3oh_c": 1.0, "pepasp_c": -1.0, "succ_c": 1.0, "co2_c": 1.0}, "id": "RC04073", "gene_reaction_rule": "WBGene00010703"}, {"subsystem": "Pyrimidine metabolism", "name": "orotidine-5-phosphate carboxy-lyase (UMP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00965", "ec-code": "4.1.1.23", "sbo": "SBO:0000176"}, "metabolites": {"ump_c": 1.0, "co2_c": 1.0, "h_c": -1.0, "orot5p_c": -1.0}, "id": "RC00965", "gene_reaction_rule": "WBGene00011559"}, {"subsystem": "Pyrimidine metabolism", "name": "ATP:uridine 5-phosphotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00964", "ec-code": "2.7.1.48", "sbo": "SBO:0000176"}, "metabolites": {"uri_c": -1.0, "ump_c": 1.0, "adp_c": 1.0, "atp_c": -1.0, "h_c": 1.0}, "id": "RC00964", "gene_reaction_rule": "WBGene00007089 or WBGene00008948"}, {"subsystem": "Histone modification", "name": "S-adenosyl-L-methionine:histone-L-lysine N6-methyltransferase (acting on monomethylated residues)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R04866", "ec-code": "2.1.1.43", "sbo": "SBO:0000176"}, "metabolites": {"amet_c": -1.0, "Nmelys_c": -1.0, "Ndmelys_c": 1.0, "h_c": 1.0, "ahcys_c": 1.0}, "id": "RC04866", "gene_reaction_rule": "(WBGene00011729 or WBGene00003040 or (WBGene00016603 or WBGene00019584) or WBGene00004782 or WBGene00019883 or WBGene00018023 or WBGene00003220 or WBGene00021515 or (WBGene00021474 or WBGene00010067 or WBGene00012302 or WBGene00010120 or WBGene00022512) or WBGene00016313 or WBGene00004781) or (WBGene00019690 or WBGene00020006 or WBGene00021282 or WBGene00008062 or WBGene00022431 or WBGene00008206)"}, {"subsystem": "Histone modification", "name": "S-adenosyl-L-methionine:histone-L-lysine N6-methyltransferase (acting on dimethylated residues)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R04867", "ec-code": "2.1.1.43", "sbo": "SBO:0000176"}, "metabolites": {"amet_c": -1.0, "Ndmelys_c": -1.0, "h_c": 1.0, "Ntmelys_c": 1.0, "ahcys_c": 1.0}, "id": "RC04867", "gene_reaction_rule": "(WBGene00011729 or WBGene00003040 or (WBGene00016603 or WBGene00019584) or WBGene00004782 or WBGene00019883 or WBGene00018023 or WBGene00003220 or WBGene00021515 or (WBGene00021474 or WBGene00010067 or WBGene00012302 or WBGene00010120 or WBGene00022512) or WBGene00016313 or WBGene00004781) or (WBGene00019690 or WBGene00020006 or WBGene00021282 or WBGene00008062 or WBGene00022431 or WBGene00008206)"}, {"subsystem": "Arachidonic acid metabolism", "name": "5-Hydroxyeicosatetraenoate demand", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"5HETE_c": -1.0}, "id": "DMN0064", "gene_reaction_rule": ""}, {"subsystem": "Fatty acid metabolism", "name": "Palmitoyl-CoA:L-carnitine O-palmitoyltransferase II", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01923", "ec-code": "2.3.1.21", "sbo": "SBO:0000176"}, "metabolites": {"pmtcoa_m": 1.0, "coa_m": -1.0, "crn_m": 1.0, "pmtcrn_m": -1.0}, "id": "RM01923", "gene_reaction_rule": "WBGene00011122"}, {"subsystem": "Pyrimidine metabolism", "name": "NADPH:oxidized-thioredoxin oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02016", "ec-code": "1.8.1.9", "sbo": "SBO:0000176"}, "metabolites": {"nadph_m": -1.0, "h_m": -1.0, "trdox_m": -1.0, "nadp_m": 1.0, "trdrd_m": 1.0}, "id": "RM02016", "gene_reaction_rule": "WBGene00015553"}, {"subsystem": "Taurine and hypotaurine metabolism", "name": "glutaurine demand", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"glutaur_c": -1.0}, "id": "DMN0059", "gene_reaction_rule": ""}, {"subsystem": "Miscellaneous", "name": "tmao and urea demand for osmotic balancing", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"tmao_c": -1.0, "urea_c": -2.0}, "id": "DMN0058", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "CO2 transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"co2_c": -1.0, "co2_m": 1.0}, "id": "TCM1287", "gene_reaction_rule": ""}, {"subsystem": "Pentose and glucuronate interconversions", "name": "ATP:D-xylulose 5-phosphotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01639", "ec-code": "2.7.1.17", "sbo": "SBO:0000176"}, "metabolites": {"xylu-D_c": -1.0, "xu5p-D_c": 1.0, "adp_c": 1.0, "atp_c": -1.0, "h_c": 1.0}, "id": "RC01639", "gene_reaction_rule": "WBGene00011147"}, {"subsystem": "Ascaroside biosynthesis", "name": "ascr2 synthesis (lumped with hydrolysis)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -2.0, "nadh_c": 1.0, "nad_c": -1.0, "coa_c": 1.0, "h_c": 1.0, "ascr2_c": 1.0, "ascr7coa_c": -1.0, "co2_c": 1.0}, "id": "RCC0234", "gene_reaction_rule": "WBGene00017123 and WBGene00000991"}, {"subsystem": "Inositol phosphate metabolism", "name": "1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate demand", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"pail34p_c": -1.0}, "id": "DMN0055", "gene_reaction_rule": ""}, {"subsystem": "Inositol phosphate metabolism", "name": "1-Phosphatidyl-1D-myo-inositol 3-phosphate demand", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"pail3p_c": -1.0}, "id": "DMN0054", "gene_reaction_rule": ""}, {"subsystem": "Ascaroside biosynthesis", "name": "ascr-coa (ascr7) hydrolysis", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"ascr7coa_c": -1.0, "h2o_c": -1.0, "ascr7_c": 1.0, "coa_c": 1.0, "h_c": 1.0}, "id": "RCC0232", "gene_reaction_rule": ""}, {"subsystem": "Ascaroside biosynthesis", "name": "ascr-coa (ascr18) hydrolysis", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"ascr18coa_c": -1.0, "coa_c": 1.0, "h2o_c": -1.0, "ascr18_c": 1.0, "h_c": 1.0}, "id": "RCC0233", "gene_reaction_rule": ""}, {"subsystem": "Alanine, aspartate and glutamate metabolism", "name": "L-Alanine:glyoxylate aminotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00369", "ec-code": "2.6.1.44", "sbo": "SBO:0000176"}, "metabolites": {"ala-L_c": -1.0, "pyr_c": 1.0, "glx_c": -1.0, "gly_c": 1.0}, "id": "RC00369", "gene_reaction_rule": "WBGene00020382 or WBGene00011767"}, {"subsystem": "Pyrimidine metabolism", "name": "3-Ureidoisobutyrate amidohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R04666", "ec-code": "3.5.1.6", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "3aib-D_c": 1.0, "3uib_c": -1.0, "co2_c": 1.0, "nh4_c": 1.0, "h_c": -2.0}, "id": "RC04666", "gene_reaction_rule": "WBGene00017440"}, {"subsystem": "Transport", "name": "trans-4-Hydroxy-L-proline transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"4hpro-LT_c": -1.0, "4hpro-LT_m": 1.0}, "id": "TCM1078", "gene_reaction_rule": ""}, {"subsystem": "Biosynthesis of unsaturated fatty acids", "name": "linoleoyl-CoA desaturase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03814", "ec-code": "1.14.19.3", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "h2o_c": 2.0, "ficytb_c": 2.0, "lnlncgcoa_c": 1.0, "lnlccoa_c": -1.0, "focytb_c": -2.0}, "id": "RC03814", "gene_reaction_rule": "WBGene00001395"}, {"subsystem": "Transport", "name": "L-Phenylalanine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"phe-L_m": -1.0, "phe-L_c": 1.0}, "id": "TCM1075", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Dihydroxyacetone phosphate transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dhap_c": 1.0, "dhap_m": -1.0}, "id": "TCM1077", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Guanine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"gua_c": -1.0, "gua_m": 1.0}, "id": "TCM1076", "gene_reaction_rule": ""}, {"subsystem": "Propanoate metabolism", "name": "3-Oxopropanoate:NAD+ oxidoreductase (decarboxylating, CoA-acetylating)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00705", "ec-code": ["1.2.1.18", "1.2.1.27"], "sbo": "SBO:0000176"}, "metabolites": {"msa_m": -1.0, "accoa_m": 1.0, "co2_m": 1.0, "nad_m": -1.0, "coa_m": -1.0, "nadh_m": 1.0}, "id": "RM00705", "gene_reaction_rule": "WBGene00000114"}, {"subsystem": "Transport", "name": "L-Asparagine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"asn-L_c": -1.0, "asn-L_m": 1.0}, "id": "TCM1070", "gene_reaction_rule": ""}, {"subsystem": "Inositol phosphate metabolism", "name": "ATP:1-phosphatidyl-1D-myo-inositol-4-phosphate 3-phosphotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R05795", "ec-code": "2.7.1.154", "sbo": "SBO:0000176"}, "metabolites": {"pail34p_c": 1.0, "pail4p_c": -1.0, "adp_c": 1.0, "atp_c": -1.0, "h_c": 1.0}, "id": "RC05795", "gene_reaction_rule": "WBGene00009552"}, {"subsystem": "Propanoate metabolism", "name": "3-Oxopropanoate:NADP+ oxidoreductase (decarboxylating, CoA-acetylating)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00706", "ec-code": "1.2.1.18", "sbo": "SBO:0000176"}, "metabolites": {"nadph_m": 1.0, "nadp_m": -1.0, "msa_m": -1.0, "co2_m": 1.0, "accoa_m": 1.0, "coa_m": -1.0}, "id": "RM00706", "gene_reaction_rule": "WBGene00000114"}, {"subsystem": "Transport", "name": "Succinate and Fumarate transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"succ_c": -1.0, "fum_c": 1.0, "succ_m": 1.0, "fum_m": -1.0}, "id": "TCM1043", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Riboflavin transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"ribflv_m": 1.0, "ribflv_c": -1.0}, "id": "TCM1044", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Succinate and L-Malate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"mal-L_c": -1.0, "succ_c": 1.0, "succ_m": -1.0, "mal-L_m": 1.0}, "id": "TCM1045", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "L-Malate and Citrate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"mal-L_c": 1.0, "cit_m": 1.0, "mal-L_m": -1.0, "cit_c": -1.0}, "id": "TCM1285", "gene_reaction_rule": "WBGene00010780 or WBGene00021345"}, {"subsystem": "Purine metabolism", "name": "hypoxanthine:NAD+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01768", "ec-code": "1.17.1.4", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "xan_c": 1.0, "hxan_c": -1.0, "h_c": 1.0, "nad_c": -1.0, "nadh_c": 1.0}, "id": "RC01768", "gene_reaction_rule": "WBGene00010083"}, {"subsystem": "Purine metabolism", "name": "Hypoxanthine:oxygen oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01769", "ec-code": "1.17.3.2", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "h2o_c": -1.0, "hxan_c": -1.0, "xan_c": 1.0, "h2o2_c": 1.0}, "id": "RC01769", "gene_reaction_rule": "WBGene00010083"}, {"subsystem": "Transport", "name": "2-Oxobutanoate transport (cytosol/mitochondria)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"2obut_c": -1.0, "2obut_m": 1.0}, "id": "TCM5059", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "L-Cysteine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"cys-L_c": 1.0, "cys-L_e": -1.0}, "id": "TCE0735", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Stachyose transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"stachyose_e": 1.0, "stachyose_c": -1.0}, "id": "TCE9072", "gene_reaction_rule": ""}, {"subsystem": "Fatty acid metabolism", "name": "fatty-acid--CoA ligase (Rtotal)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00390", "ec-code": "6.2.1.3", "sbo": "SBO:0000176"}, "metabolites": {"Rtotalcoa_c": 1.0, "atp_c": -1.0, "ppi_c": 1.0, "coa_c": -1.0, "amp_c": 1.0, "Rtotal_c": -1.0}, "id": "RCC0128", "gene_reaction_rule": "WBGene00009221 or WBGene00020343 or WBGene00018152 or WBGene00013575 or WBGene00022037 or WBGene00019920 or WBGene00016716 or WBGene00011173"}, {"subsystem": "Fatty acid metabolism", "name": "fatty-acid--CoA ligase (Rtotal)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00390", "ec-code": "6.2.1.3", "sbo": "SBO:0000176"}, "metabolites": {"atp_c": -1.0, "ppi_c": 1.0, "Rtotal3_c": -1.0, "coa_c": -1.0, "amp_c": 1.0, "Rtotal3coa_c": 1.0}, "id": "RCC0129", "gene_reaction_rule": "WBGene00009221 or WBGene00020343 or WBGene00018152 or WBGene00013575 or WBGene00022037 or WBGene00019920 or WBGene00016716 or WBGene00011173"}, {"subsystem": "Transport", "name": "cAMP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"h2o_c": -1.0, "atp_c": -1.0, "camp_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "pi_c": 1.0, "camp_e": 1.0}, "id": "TCE0743", "gene_reaction_rule": ""}, {"subsystem": "Histidine metabolism", "name": "L-histidine ammonia-lyase (urocanate-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01168", "ec-code": "4.3.1.3", "sbo": "SBO:0000176"}, "metabolites": {"urcan_c": 1.0, "nh4_c": 1.0, "his-L_c": -1.0}, "id": "RC01168", "gene_reaction_rule": "WBGene00009813"}, {"subsystem": "Synthesis and degradation of ketone bodies", "name": "succinyl-CoA:acetoacetate CoA-transferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00410", "ec-code": "2.8.3.5", "sbo": "SBO:0000176"}, "metabolites": {"succoa_m": -1.0, "succ_m": 1.0, "aacoa_m": 1.0, "acac_m": -1.0}, "id": "RM00410", "gene_reaction_rule": "WBGene00007330"}, {"subsystem": "Carnitine shuttle", "name": "Acyl-CoA:L-carnitine O-acyltransferase I (cis-11,12-methyleneoctadecanoyl-CoA)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "2.3.1.21", "sbo": "SBO:0000176"}, "metabolites": {"crn_c": -1.0, "fa19c11crn_c": 1.0, "fa19c11coa_c": -1.0, "coa_c": 1.0}, "id": "RCC0120", "gene_reaction_rule": "WBGene00012907 or WBGene00021703 or WBGene00019644 or WBGene00008629 or WBGene00020911"}, {"subsystem": "Carnitine shuttle", "name": "Acyl-CoA:L-carnitine O-acyltransferase I (Fatty acyl [C15:iso] CoA)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "2.3.1.21", "sbo": "SBO:0000176"}, "metabolites": {"crn_c": -1.0, "fa15p0isocoa_c": -1.0, "coa_c": 1.0, "fa15p0isocrn_c": 1.0}, "id": "RCC0121", "gene_reaction_rule": "WBGene00012907 or WBGene00021703 or WBGene00019644 or WBGene00008629 or WBGene00020911"}, {"subsystem": "Carnitine shuttle", "name": "Acyl-CoA:L-carnitine O-acyltransferase I (Fatty acyl [C17:iso] CoA)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "2.3.1.21", "sbo": "SBO:0000176"}, "metabolites": {"crn_c": -1.0, "fa17p0isocoa_c": -1.0, "coa_c": 1.0, "fa17p0isocrn_c": 1.0}, "id": "RCC0122", "gene_reaction_rule": "WBGene00012907 or WBGene00021703 or WBGene00019644 or WBGene00008629 or WBGene00020911"}, {"subsystem": "Histidine metabolism", "name": "L-histidine carboxy-lyase (histamine-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01167", "ec-code": "4.1.1.28", "sbo": "SBO:0000176"}, "metabolites": {"co2_c": 1.0, "hista_c": 1.0, "h_c": -1.0, "his-L_c": -1.0}, "id": "RC01167", "gene_reaction_rule": "WBGene00000239 or WBGene00001839 or WBGene00006562"}, {"subsystem": "Fatty acid elongation", "name": "merged fatty acid elongation (C18 to C24)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R10825", "R10826", "R10827", "R10828"], "ec-code": ["2.3.1.199", "1.1.1.330", "4.2.1.134", "1.3.1.93"], "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": 3.0, "malcoa_c": -3.0, "nadph_c": -6.0, "stcoa_c": -1.0, "nadp_c": 6.0, "coa_c": 3.0, "h_c": -9.0, "lgnccoa_c": 1.0, "co2_c": 3.0}, "id": "RCC0124", "gene_reaction_rule": "WBGene00001239 and WBGene00002891 and WBGene00020517 and WBGene00000198"}, {"subsystem": "Peroxisomal fatty acid beta oxidation", "name": "beta oxidation of very long chain fatty acid", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R00388", "R02685", "R01778", "R00391"], "ec-code": ["1.3.3.6", "4.2.1.17", "1.1.1.211", "1.1.1.35", "2.3.1.16"], "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -3.0, "h2o_c": -3.0, "accoa_c": 3.0, "stcoa_c": 1.0, "h2o2_c": 3.0, "coa_c": -3.0, "h_c": 3.0, "nad_c": -3.0, "lgnccoa_c": -1.0, "nadh_c": 3.0}, "id": "RCC0125", "gene_reaction_rule": "(WBGene00008167 or WBGene00008564 or WBGene00008565 or WBGene00008566 or WBGene00008567 or WBGene00019060 or WBGene00010336) and (WBGene00000991 or WBGene00017123) and WBGene00013284"}, {"subsystem": "Peroxisomal fatty acid beta oxidation", "name": "Beta oxidation of stcoa (peroxisomal)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R00388", "R02685", "R01778", "R00391"], "ec-code": ["1.3.3.6", "4.2.1.17", "1.1.1.211", "1.1.1.35", "2.3.1.16"], "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "h2o_c": -1.0, "nad_c": -1.0, "h2o2_c": 1.0, "pmtcoa_c": 1.0, "stcoa_c": -1.0, "coa_c": -1.0, "h_c": 1.0, "accoa_c": 1.0, "nadh_c": 1.0}, "id": "RCC0126", "gene_reaction_rule": "(WBGene00008167 or WBGene00008564 or WBGene00008565 or WBGene00008566 or WBGene00008567 or WBGene00019060 or WBGene00010336) and (WBGene00000991 or WBGene00017123) and WBGene00013284"}, {"subsystem": "Fatty acid metabolism", "name": "fatty-acid--CoA ligase (Rtotal6)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00390", "ec-code": "6.2.1.3", "sbo": "SBO:0000176"}, "metabolites": {"atp_c": -1.0, "ppi_c": 1.0, "coa_c": -1.0, "Rtotal6_c": -1.0, "Rtotal6coa_c": 1.0, "amp_c": 1.0}, "id": "RCC0127", "gene_reaction_rule": "WBGene00009221 or WBGene00020343 or WBGene00018152 or WBGene00013575 or WBGene00022037 or WBGene00019920 or WBGene00016716 or WBGene00011173"}, {"subsystem": "Glycerophospholipid metabolism", "name": "CTP:choline-phosphate cytidylyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01890", "ec-code": "2.7.7.15", "sbo": "SBO:0000176"}, "metabolites": {"ctp_c": -1.0, "cholp_c": -1.0, "ppi_c": 1.0, "cdpchol_c": 1.0, "h_c": -1.0}, "id": "RC01890", "gene_reaction_rule": "WBGene00017241"}, {"subsystem": "Pentose and glucuronate interconversions", "name": "xylitol dehydrogenase (D-xyulose-forming)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01896", "ec-code": "1.1.1.14", "sbo": "SBO:0000176"}, "metabolites": {"xylt_c": -1.0, "nadh_c": 1.0, "h_c": 1.0, "nad_c": -1.0, "xylu-D_c": 1.0}, "id": "RC01896", "gene_reaction_rule": "WBGene00011003 or WBGene00011004"}, {"subsystem": "Exchange with the environment", "name": "androsterone glucuronide exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"andrstrnglc_e": -1.0}, "id": "EX11135", "gene_reaction_rule": ""}, {"subsystem": "Retinol metabolism", "name": "cis-retinyl ester demand", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000632"}, "metabolites": {"retpalm-cis-11_c": -1.0}, "id": "SNK0029", "gene_reaction_rule": ""}, {"subsystem": "Retinol metabolism", "name": "all trans retinyl ester demand", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000632"}, "metabolites": {"retpalm_c": -1.0}, "id": "SNK0028", "gene_reaction_rule": ""}, {"subsystem": "Sphingolipid metabolism", "name": "Sphingosine 1-phosphate phosphohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R06521", "ec-code": "3.1.3.4", "sbo": "SBO:0000176"}, "metabolites": {"sphs1p_ce_c": -1.0, "h2o_c": -1.0, "pi_c": 1.0, "sphings_ce_c": 1.0}, "id": "RC06521", "gene_reaction_rule": "WBGene00008749 or WBGene00018756 or WBGene00020895"}, {"subsystem": "Sphingolipid metabolism", "name": "Sphinganine 1-phosphate phosphohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R06520", "ec-code": "3.1.3.4", "sbo": "SBO:0000176"}, "metabolites": {"sphgn_ce_c": 1.0, "h2o_c": -1.0, "pi_c": 1.0, "sph1p_ce_c": -1.0}, "id": "RC06520", "gene_reaction_rule": "WBGene00008749 or WBGene00018756 or WBGene00020895"}, {"subsystem": "Sphingolipid metabolism", "name": "Ceramide 1-phosphate phosphohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R06522", "ec-code": "3.1.3.4", "sbo": "SBO:0000176"}, "metabolites": {"crmp_ce_c": -1.0, "crm_ce_c": 1.0, "h2o_c": -1.0, "pi_c": 1.0}, "id": "RC06522", "gene_reaction_rule": "WBGene00008749 or WBGene00018756 or WBGene00020895"}, {"subsystem": "Exchange with the environment", "name": "RNA component of bacterial diet exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"rna_BAC_e": -1.0}, "id": "EXC0052", "gene_reaction_rule": ""}, {"subsystem": "Fatty acid metabolism", "name": "fatty-acid--CoA ligase (dodecanoate)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00390", "ec-code": "6.2.1.3", "sbo": "SBO:0000176"}, "metabolites": {"atp_c": -1.0, "ddca_c": -1.0, "ppi_c": 1.0, "ddcacoa_c": 1.0, "coa_c": -1.0, "amp_c": 1.0}, "id": "RCC0055", "gene_reaction_rule": "WBGene00009221 or WBGene00020343 or WBGene00018152 or WBGene00013575 or WBGene00022037 or WBGene00019920 or WBGene00016716 or WBGene00011173"}, {"subsystem": "Fatty acid metabolism", "name": "fatty-acid--CoA ligase (tetradecanoate)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00390", "ec-code": "6.2.1.3", "sbo": "SBO:0000176"}, "metabolites": {"atp_c": -1.0, "ppi_c": 1.0, "coa_c": -1.0, "amp_c": 1.0, "ttdca_c": -1.0, "tdcoa_c": 1.0}, "id": "RCC0056", "gene_reaction_rule": "WBGene00009221 or WBGene00020343 or WBGene00018152 or WBGene00013575 or WBGene00022037 or WBGene00019920 or WBGene00016716 or WBGene00011173"}, {"subsystem": "Exchange with the environment", "name": "Protein component of bacterial diet exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"protein_BAC_e": -1.0}, "id": "EXC0051", "gene_reaction_rule": ""}, {"subsystem": "Primary bile acid biosynthesis", "name": "D-bifunctional protein", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": ["R04813", "R04812"], "ec-code": ["4.2.1.107", "1.1.1.35"], "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "cholcoaone_c": 1.0, "h_c": 1.0, "nad_c": -1.0, "cholcoads_c": -1.0, "nadh_c": 1.0}, "id": "RCC0050", "gene_reaction_rule": "WBGene00000988 or WBGene00000991 or WBGene00017123"}, {"subsystem": "Nicotinate and nicotinamide metabolism", "name": "poly(ADP-ribose) glycohydrolase (PARG)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "3.2.1.143", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "polyadprib_c": -1.0, "adprib_c": 1.0}, "id": "RCC0051", "gene_reaction_rule": "WBGene00004051 or WBGene00004052"}, {"subsystem": "Exchange with the environment", "name": "Peptidoglycan subunit of bacteria exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"peptido_BAC_e": -1.0}, "id": "EXC0054", "gene_reaction_rule": ""}, {"subsystem": "Pentose and glucuronate interconversions", "name": "UDPglucuronate beta-D-glucuronosyltransferase (acceptor-unspecific); beta-D-glucuronoside glucuronosohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R01383", "R01478"], "ec-code": ["2.4.1.17", "3.2.1.31"], "sbo": "SBO:0000176"}, "metabolites": {"udp_c": 1.0, "h2o_c": -1.0, "glcur_c": 1.0, "h_c": 1.0, "udpglcur_c": -1.0}, "id": "RCC0053", "gene_reaction_rule": "(WBGene00015371 or WBGene00016959 or WBGene00017334 or WBGene00018789 or WBGene00019235 or WBGene00019379 or WBGene00007072 or WBGene00020594 or WBGene00020593 or WBGene00020592 or WBGene00019232 or WBGene00019233 or WBGene00008097 or WBGene00013901 or WBGene00007422 or WBGene00013900 or WBGene00019515 or WBGene00007073 or WBGene00019516 or WBGene00007885 or WBGene00007455 or WBGene00007650 or WBGene00016762 or WBGene00015692 or WBGene00015695 or WBGene00015694 or WBGene00021709 or WBGene00013903 or WBGene00011340 or WBGene00021464 or WBGene00018543 or WBGene00007946 or WBGene00009255 or WBGene00044286 or WBGene00017315 or WBGene00017332 or WBGene00017333 or WBGene00017329 or WBGene00013905 or WBGene00017331 or WBGene00017336 or WBGene00017959 or WBGene00008485 or WBGene00008486 or WBGene00021372 or WBGene00015141 or WBGene00011006 or WBGene00015965 or WBGene00007070 or WBGene00013906 or WBGene00011564 or WBGene00015369 or WBGene00018931 or WBGene00020182 or WBGene00012013 or WBGene00011452 or WBGene00011453 or WBGene00009450 or WBGene00011238 or WBGene00013904 or WBGene00007402 or WBGene00018206 or WBGene00010904 or WBGene00015449 or WBGene00015577 or WBGene00008583 or WBGene00015739 or WBGene00019234 or WBGene00020587) and (WBGene00013693)"}, {"subsystem": "Ubiquinone and other terpenoid-quinone biosynthesis", "name": "4-Hydroxybenzoyl-CoA hydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01301", "ec-code": "3.1.2.23", "sbo": "SBO:0000176"}, "metabolites": {"4hbzcoa_c": -1.0, "4hbz_c": 1.0, "h2o_c": -1.0, "coa_c": 1.0, "h_c": 1.0}, "id": "RC01301", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Phosphatidylethanolamine (bacteria) exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"pe_BAC_e": -1.0}, "id": "EXC0058", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Phosphatidylglycerol (bacteria) exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"pg_BAC_e": -1.0}, "id": "EXC0059", "gene_reaction_rule": ""}, {"subsystem": "Carnitine shuttle", "name": "Acyl-CoA:L-carnitine O-acyltransferase I (Dodecanoyl-CoA )", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "2.3.1.21", "sbo": "SBO:0000176"}, "metabolites": {"crn_c": -1.0, "ddcacoa_c": -1.0, "ddcrn_c": 1.0, "coa_c": 1.0}, "id": "RCC0058", "gene_reaction_rule": "WBGene00012907 or WBGene00021703 or WBGene00019644 or WBGene00008629 or WBGene00020911"}, {"subsystem": "Cysteine and methionine metabolism", "name": "L-Cysteine hydrogen-sulfide-lyase (deaminating, pyruvate-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00782", "ec-code": "4.4.1.1", "sbo": "SBO:0000176"}, "metabolites": {"cys-L_c": -1.0, "h2o_c": -1.0, "pyr_c": 1.0, "nh4_c": 1.0, "h2s_c": 1.0}, "id": "RC00782", "gene_reaction_rule": "WBGene00007533 or WBGene00009048 or WBGene00022856"}, {"subsystem": "Riboflavin metabolism", "name": "riboflavin kinase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00549", "ec-code": "2.7.1.26", "sbo": "SBO:0000176"}, "metabolites": {"h_c": 1.0, "fmn_c": 1.0, "adp_c": 1.0, "atp_c": -1.0, "ribflv_c": -1.0}, "id": "RC00549", "gene_reaction_rule": "WBGene00011224"}, {"subsystem": "Riboflavin metabolism", "name": "riboflavin-5-phosphate phosphohydrolase (acid optimum)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00548", "ec-code": "3.1.3.2", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "pi_c": 1.0, "fmn_c": -1.0, "ribflv_c": 1.0}, "id": "RC00548", "gene_reaction_rule": "((WBGene00009146 or WBGene00014076 or WBGene00007328 or WBGene00007331) or (WBGene00020471 or WBGene00015161 or WBGene00011262) or WBGene00022379 or WBGene00008531) or (WBGene00206373 or WBGene00008802 or WBGene00008801 or WBGene00022246 or WBGene00004020 or WBGene00016152 or WBGene00004023 or WBGene00018696 or WBGene00011879 or WBGene00022181)"}, {"subsystem": "Galactose metabolism", "name": "ATP:D-galactose 1-phosphotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01092", "ec-code": "2.7.1.6", "sbo": "SBO:0000176"}, "metabolites": {"h_c": 1.0, "gal_c": -1.0, "adp_c": 1.0, "atp_c": -1.0, "gal1p_c": 1.0}, "id": "RC01092", "gene_reaction_rule": "WBGene00006461"}, {"subsystem": "Galactose metabolism", "name": "galactitol:NAD+ 1-oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01093", "ec-code": "1.1.1.21", "sbo": "SBO:0000176"}, "metabolites": {"nad_c": 1.0, "gal_c": -1.0, "galt_c": 1.0, "h_c": -1.0, "nadh_c": -1.0}, "id": "RC01093", "gene_reaction_rule": "WBGene00012722"}, {"subsystem": "Galactose metabolism", "name": "galactitol:NADP+ 1-oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01095", "ec-code": "1.1.1.21", "sbo": "SBO:0000176"}, "metabolites": {"galt_c": 1.0, "gal_c": -1.0, "nadph_c": -1.0, "h_c": -1.0, "nadp_c": 1.0}, "id": "RC01095", "gene_reaction_rule": "WBGene00012722"}, {"subsystem": "Transport", "name": "O-Acetylcarnitine and L-Carnitine transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"acrn_c": -1.0, "crn_c": 1.0, "acrn_m": 1.0, "crn_m": -1.0}, "id": "TCM1096", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "\"Adenosine 3',5'-bisphosphate\" transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"pap_m": 1.0, "pap_c": -1.0}, "id": "TCM1095", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "S-Adenosyl-L-homocysteine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"ahcys_c": -1.0, "ahcys_m": 1.0}, "id": "TCM1091", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "(S)-3-Methyl-2-oxopentanoate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"3mop_c": -1.0, "3mop_m": 1.0}, "id": "TCM1098", "gene_reaction_rule": ""}, {"subsystem": "Purine metabolism", "name": "Guanosine 3,5-cyclic phosphate 5-nucleotidohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01234", "ec-code": "3.1.4.17", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "gmp_c": 1.0, "h_c": 1.0, "35cgmp_c": -1.0}, "id": "RC01234", "gene_reaction_rule": " WBGene00011433 or WBGene00011146 or WBGene00008443 or WBGene00016328"}, {"subsystem": "N-Glycan biosynthesis", "name": "GDP-D-mannose:D-Man-alpha-(1->3)-D-Man-beta-(1->4)-D-GlcNAc-beta-(1->4)-D-GlcNAc-diphosphodolichol alpha-6-mannosyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R06238", "ec-code": "2.4.1.257", "sbo": "SBO:0000176"}, "metabolites": {"m2mpdol_c": 1.0, "gdpmann_c": -1.0, "gdp_c": 1.0, "m1mpdol_c": -1.0, "h_c": 1.0}, "id": "RC06238", "gene_reaction_rule": "WBGene00017282"}, {"subsystem": "Purine metabolism", "name": "Xanthosine-5-phosphate:ammonia ligase (AMP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01230", "ec-code": "6.3.5.2", "sbo": "SBO:0000176"}, "metabolites": {"xmp_c": -1.0, "gmp_c": 1.0, "atp_c": -1.0, "ppi_c": 1.0, "h_c": 2.0, "nh4_c": -1.0, "amp_c": 1.0}, "id": "RC01230", "gene_reaction_rule": "WBGene00010912"}, {"subsystem": "Purine metabolism", "name": "Xanthosine-5-phosphate:L-glutamine amido-ligase (AMP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01231", "ec-code": "6.3.5.2", "sbo": "SBO:0000176"}, "metabolites": {"xmp_c": -1.0, "h2o_c": -1.0, "gmp_c": 1.0, "atp_c": -1.0, "gln-L_c": -1.0, "glu-L_c": 1.0, "ppi_c": 1.0, "amp_c": 1.0, "h_c": 2.0}, "id": "RC01231", "gene_reaction_rule": "WBGene00010912"}, {"subsystem": "Primary bile acid biosynthesis", "name": "3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate,NADPH:oxygen oxidoreductase (26-hydroxylating)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R08761", "ec-code": "1.14.13.15", "sbo": "SBO:0000176"}, "metabolites": {"nadph_m": -1.0, "h2o_m": 1.0, "nadp_m": 1.0, "o2_m": -1.0, "thcholst_m": -1.0, "thcholstoic_m": 1.0}, "id": "RM08761", "gene_reaction_rule": "WBGene00000905"}, {"subsystem": "Ubiquinone and other terpenoid-quinone biosynthesis", "name": "4-hydroxybenzoyl-CoA formation", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R08767", "sbo": "SBO:0000176"}, "metabolites": {"4cmcoa_m": -1.0, "h2o_m": -1.0, "accoa_m": 1.0, "nadh_m": 1.0, "4hbzcoa_m": 1.0, "nad_m": -1.0, "coa_m": -1.0, "h_m": 1.0}, "id": "RM08767", "gene_reaction_rule": ""}, {"subsystem": "Ubiquinone and other terpenoid-quinone biosynthesis", "name": "3-(4-hydroxyphenyl)lactate hydro-lyase (4-coumarate-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R08766", "ec-code": "4.2.1.-", "sbo": "SBO:0000176"}, "metabolites": {"34hpl_m": -1.0, "T4hcinnm_m": 1.0, "h2o_m": 1.0}, "id": "RM08766", "gene_reaction_rule": ""}, {"subsystem": "Glycolysis / Gluconeogenesis", "name": "ATP:alpha-D-glucose 6-phosphotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01786", "ec-code": "2.7.1.1", "sbo": "SBO:0000176"}, "metabolites": {"g6p-A_c": 1.0, "glc-D-A_c": -1.0, "adp_c": 1.0, "atp_c": -1.0, "h_c": 1.0}, "id": "RC01786", "gene_reaction_rule": "WBGene00008780 or WBGene00010416 or WBGene00022306"}, {"subsystem": "Fructose and mannose metabolism", "name": "D-sorbitol reductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01787", "ec-code": "1.1.1.21", "sbo": "SBO:0000176"}, "metabolites": {"nadp_c": 1.0, "nadph_c": -1.0, "h_c": -1.0, "glc-D_c": -1.0, "sbt-D_c": 1.0}, "id": "RC01787", "gene_reaction_rule": "WBGene00012722"}, {"subsystem": "Exchange with the environment", "name": "trimethylamine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"tma_e": -1.0}, "id": "EX00565", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "D-Glucarate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"glcr_e": -1.0}, "id": "EX00818", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "trans-4-Hydroxycinnamate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"T4hcinnm_e": -1.0}, "id": "EX00811", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Prostaglandin E2 exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"prostge2_e": -1.0}, "id": "EX00584", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Propylene glycol exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"12ppd-R_e": -1.0}, "id": "EX00583", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Selenocysteine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"selcys_e": -1.0}, "id": "EX05688", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Choline phosphate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"cholp_e": -1.0}, "id": "EX00588", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "sphingosylphosphorylcholine  exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"spc_ce_e": -1.0}, "id": "EXC0203", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Ceramide 1-phosphate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"crmp_ce_e": -1.0}, "id": "EXC0202", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Sphingomyelin exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"sphmyln_ce_e": -1.0}, "id": "EXC0201", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Sphinganine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"sphgn_ce_e": -1.0}, "id": "EXC0207", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Galactitol exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"galt_e": -1.0}, "id": "EX01697", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Sphinganine 1-phosphate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"sph1p_ce_e": -1.0}, "id": "EXC0208", "gene_reaction_rule": ""}, {"subsystem": "Inositol phosphate metabolism", "name": "ATP:1-phosphatidyl-1D-myo-inositol 5-phosphotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R10951", "ec-code": "2.7.1.150", "sbo": "SBO:0000176"}, "metabolites": {"h_c": 1.0, "pail5p_c": 1.0, "pail_c": -1.0, "atp_c": -1.0, "adp_c": 1.0}, "id": "RC10951", "gene_reaction_rule": "WBGene00004089"}, {"subsystem": "Exchange with the environment", "name": "tetradecanoate (n-C14:0) exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"ttdca_e": -1.0}, "id": "EX06424", "gene_reaction_rule": ""}, {"subsystem": "Pentose and glucuronate interconversions", "name": "xylitol:NADP+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01431", "ec-code": "1.1.1.21", "sbo": "SBO:0000176"}, "metabolites": {"xylt_c": 1.0, "nadp_c": 1.0, "nadph_c": -1.0, "h_c": -1.0, "xyl-D_c": -1.0}, "id": "RC01431", "gene_reaction_rule": "WBGene00012722"}, {"subsystem": "Transport", "name": "Phosphatidylserine (bacteria) transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"h2o_c": -1.0, "adp_c": 1.0, "atp_c": -1.0, "h_c": 1.0, "ps_BAC_c": -1.0, "ps_BAC_m": 1.0, "pi_c": 1.0}, "id": "TCM0124", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "dUDP and dCDP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dcdp_m": -1.0, "dudp_m": 1.0, "dudp_c": -1.0, "dcdp_c": 1.0}, "id": "TCM0125", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "dUTP and ATP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"atp_m": -1.0, "dutp_m": 1.0, "dutp_c": -1.0, "atp_c": 1.0}, "id": "TCM0126", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "dGTP and dCDP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dcdp_m": -1.0, "dgtp_c": -1.0, "dgtp_m": 1.0, "dcdp_c": 1.0}, "id": "TCM0127", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "dADP and dCDP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dcdp_m": 1.0, "dadp_c": 1.0, "dcdp_c": -1.0, "dadp_m": -1.0}, "id": "TCM0121", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "\"5,6,7,8-Tetrahydrofolate\" exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"thf_e": -1.0}, "id": "EX00101", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "dTDP and dCDP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dcdp_m": 1.0, "dtdp_m": -1.0, "dtdp_c": 1.0, "dcdp_c": -1.0}, "id": "TCM0128", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Inosine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"ins_m": 1.0, "ins_c": -1.0}, "id": "TCM0129", "gene_reaction_rule": ""}, {"subsystem": "Fructose and mannose metabolism", "name": "D-mannose 6-phosphate 1,6-phosphomutase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01818", "ec-code": "5.4.2.8", "sbo": "SBO:0000176"}, "metabolites": {"man1p_c": -1.0, "man6p_c": 1.0}, "id": "RC01818", "gene_reaction_rule": "WBGene00009925"}, {"subsystem": "Mitochondrial fatty acid beta oxidation", "name": "Beta oxidation of eicosapentanoic acid (mitochondrial)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R00392", "R03224", "R02685", "R01778", "R00391"], "ec-code": ["1.3.8.7", "5.3.3.8", "4.2.1.17", "1.1.1.211", "1.1.1.35", "2.3.1.16"], "sbo": "SBO:0000176"}, "metabolites": {"tmndnccoa_m": -1.0, "fa16p4n3coa_m": 1.0, "h2o_m": -2.0, "fad_m": -1.0, "accoa_m": 2.0, "nadh_m": 2.0, "nad_m": -2.0, "coa_m": -2.0, "h_m": 2.0, "fadh2_m": 1.0}, "id": "RMC0098", "gene_reaction_rule": "(WBGene00020812 or WBGene00019406 or WBGene00020366 or WBGene00017125) and (WBGene00001153 or WBGene00007130) and ((WBGene00001155 or WBGene00001156) or (WBGene00020347 or WBGene00001150) or WBGene00001152) and ((WBGene00020347 or WBGene00001150) or (WBGene00007129 or WBGene00010035 or WBGene00001157 or WBGene00001158 or WBGene00019978)) and (WBGene00015125 or WBGene00009952)"}, {"subsystem": "Carnitine shuttle", "name": "Acyl-CoA:L-carnitine O-acyltransferase II (intermediary fatty acyl [C8:1]-CoA)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "2.3.1.21", "sbo": "SBO:0000176"}, "metabolites": {"fa8p1n3coa_m": 1.0, "coa_m": -1.0, "fa8p1n3crn_m": -1.0, "crn_m": 1.0}, "id": "RMC0099", "gene_reaction_rule": "WBGene00011122"}, {"subsystem": "Terpenoid backbone biosynthesis", "name": " prenyl protein peptidase; Ste24 endopeptidase (acting on geranyl-geranyl moiety)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": ["3.4.24.84", "3.4.22.-"], "sbo": "SBO:0000176"}, "metabolites": {"protSger_c": -1.0, "pepd_c": 1.0, "h2o_c": -1.0, "protSgerC_c": 1.0}, "id": "RCC0033", "gene_reaction_rule": "WBGene00001405 or WBGene00001406"}, {"subsystem": "Mitochondrial fatty acid beta oxidation", "name": "Beta oxidation of intermediary fatty acid C14:2 (mitochondrial)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R00392", "R04319", "R03224", "R02685", "R01778", "R00391"], "ec-code": ["1.3.8.7", "5.3.3.8", "1.3.1.34", "4.2.1.17", "1.1.1.211", "1.1.1.35", "2.3.1.16"], "sbo": "SBO:0000176"}, "metabolites": {"fadh2_m": 2.0, "nadph_m": -1.0, "h2o_m": -3.0, "nadp_m": 1.0, "fad_m": -2.0, "accoa_m": 3.0, "occoa_m": 1.0, "nadh_m": 3.0, "nad_m": -3.0, "coa_m": -3.0, "h_m": 2.0, "fa14p2n6coa_m": -1.0}, "id": "RMC0092", "gene_reaction_rule": "(WBGene00020812 or WBGene00019406 or WBGene00020366 or WBGene00017125) and (WBGene00001153 or WBGene00007130) and (WBGene00012177 or WBGene00011467) and ((WBGene00001155 or WBGene00001156) or (WBGene00020347 or WBGene00001150) or WBGene00001152) and ((WBGene00020347 or WBGene00001150) or (WBGene00007129 or WBGene00010035 or WBGene00001157 or WBGene00001158 or WBGene00019978)) and (WBGene00015125 or WBGene00009952)"}, {"subsystem": "Mitochondrial fatty acid beta oxidation", "name": "Beta oxidation of eicosatrieonic acid (mitochondrial)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R00392", "R03224", "R02685", "R01778", "R00391"], "ec-code": ["1.3.8.7", "4.2.1.17", "1.1.1.211", "1.1.1.35", "2.3.1.16"], "sbo": "SBO:0000176"}, "metabolites": {"fa16p3n6coa_m": 1.0, "dlnlcgcoa_m": -1.0, "h2o_m": -2.0, "fad_m": -2.0, "accoa_m": 2.0, "nadh_m": 2.0, "nad_m": -2.0, "coa_m": -2.0, "h_m": 2.0, "fadh2_m": 2.0}, "id": "RMC0093", "gene_reaction_rule": "(WBGene00020812 or WBGene00019406 or WBGene00020366 or WBGene00017125) and ((WBGene00001155 or WBGene00001156) or (WBGene00020347 or WBGene00001150) or WBGene00001152) and ((WBGene00020347 or WBGene00001150) or (WBGene00007129 or WBGene00010035 or WBGene00001157 or WBGene00001158 or WBGene00019978)) and (WBGene00015125 or WBGene00009952)"}, {"subsystem": "Mitochondrial fatty acid beta oxidation", "name": "Beta oxidation of vaccenic acid (mitochondrial)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R00392", "R02685", "R01778", "R00391"], "ec-code": ["1.3.8.7", "5.3.3.8", "4.2.1.17", "1.1.1.211", "1.1.1.35", "2.3.1.16"], "sbo": "SBO:0000176"}, "metabolites": {"vacccoa_m": -1.0, "h2o_m": -5.0, "fad_m": -4.0, "accoa_m": 5.0, "occoa_m": 1.0, "nadh_m": 5.0, "nad_m": -5.0, "coa_m": -5.0, "h_m": 5.0, "fadh2_m": 4.0}, "id": "RMC0090", "gene_reaction_rule": "(WBGene00020812 or WBGene00019406 or WBGene00020366 or WBGene00017125) and (WBGene00001153 or WBGene00007130) and ((WBGene00001155 or WBGene00001156) or (WBGene00020347 or WBGene00001150) or WBGene00001152) and ((WBGene00020347 or WBGene00001150) or (WBGene00007129 or WBGene00010035 or WBGene00001157 or WBGene00001158 or WBGene00019978)) and (WBGene00015125 or WBGene00009952)"}, {"subsystem": "Mitochondrial fatty acid beta oxidation", "name": "Beta oxidation of linoleic acid (mitochondrial)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R00392", "R02685", "R01778", "R00391"], "ec-code": ["1.3.8.7", "4.2.1.17", "1.1.1.211", "1.1.1.35", "2.3.1.16"], "sbo": "SBO:0000176"}, "metabolites": {"lnlccoa_m": -1.0, "h2o_m": -2.0, "fad_m": -2.0, "accoa_m": 2.0, "nadh_m": 2.0, "nad_m": -2.0, "coa_m": -2.0, "h_m": 2.0, "fadh2_m": 2.0, "fa14p2n6coa_m": 1.0}, "id": "RMC0091", "gene_reaction_rule": "(WBGene00020812 or WBGene00019406 or WBGene00020366 or WBGene00017125) and ((WBGene00001155 or WBGene00001156) or (WBGene00020347 or WBGene00001150) or WBGene00001152) and ((WBGene00020347 or WBGene00001150) or (WBGene00007129 or WBGene00010035 or WBGene00001157 or WBGene00001158 or WBGene00019978)) and (WBGene00015125 or WBGene00009952)"}, {"subsystem": "Mitochondrial fatty acid beta oxidation", "name": "Beta oxidation of eicosatetraeonic acid (mitochondrial)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R00392", "R03224", "R02685", "R01778", "R00391"], "ec-code": ["1.3.8.7", "4.2.1.17", "1.1.1.211", "1.1.1.35", "2.3.1.16"], "sbo": "SBO:0000176"}, "metabolites": {"eicostetcoa_m": -1.0, "fa16p4n3coa_m": 1.0, "h2o_m": -2.0, "fad_m": -2.0, "accoa_m": 2.0, "nadh_m": 2.0, "nad_m": -2.0, "coa_m": -2.0, "h_m": 2.0, "fadh2_m": 2.0}, "id": "RMC0096", "gene_reaction_rule": "(WBGene00020812 or WBGene00019406 or WBGene00020366 or WBGene00017125) and ((WBGene00001155 or WBGene00001156) or (WBGene00020347 or WBGene00001150) or WBGene00001152) and ((WBGene00020347 or WBGene00001150) or (WBGene00007129 or WBGene00010035 or WBGene00001157 or WBGene00001158 or WBGene00019978)) and (WBGene00015125 or WBGene00009952)"}, {"subsystem": "Mitochondrial fatty acid beta oxidation", "name": "Beta oxidation of intermediary fatty acid C16:4 (mitochondrial)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R00392", "R04319", "R03224", "R02685", "R01778", "R00391"], "ec-code": ["1.3.8.7", "5.3.3.8", "1.3.1.34", "4.2.1.17", "1.1.1.211", "1.1.1.35", "2.3.1.16"], "sbo": "SBO:0000176"}, "metabolites": {"fa8p1n3coa_m": 1.0, "nadph_m": -2.0, "fa16p4n3coa_m": -1.0, "h2o_m": -4.0, "nadp_m": 2.0, "fad_m": -3.0, "accoa_m": 4.0, "nadh_m": 4.0, "nad_m": -4.0, "coa_m": -4.0, "h_m": 2.0, "fadh2_m": 3.0}, "id": "RMC0097", "gene_reaction_rule": "(WBGene00020812 or WBGene00019406 or WBGene00020366 or WBGene00017125) and (WBGene00001153 or WBGene00007130) and (WBGene00012177 or WBGene00011467) and ((WBGene00001155 or WBGene00001156) or (WBGene00020347 or WBGene00001150) or WBGene00001152) and ((WBGene00020347 or WBGene00001150) or (WBGene00007129 or WBGene00010035 or WBGene00001157 or WBGene00001158 or WBGene00019978)) and (WBGene00015125 or WBGene00009952)"}, {"subsystem": "Mitochondrial fatty acid beta oxidation", "name": "Beta oxidation of intermediary fatty acid C16:3 (mitochondrial)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R00392", "R04319", "R03224", "R02685", "R01778", "R00391"], "ec-code": ["1.3.8.7", "5.3.3.8", "1.3.1.34", "4.2.1.17", "1.1.1.211", "1.1.1.35", "2.3.1.16"], "sbo": "SBO:0000176"}, "metabolites": {"fa16p3n6coa_m": -1.0, "fa14p2n6coa_m": 1.0, "nadph_m": -1.0, "h2o_m": -1.0, "nadp_m": 1.0, "fad_m": -1.0, "accoa_m": 1.0, "nadh_m": 1.0, "nad_m": -1.0, "coa_m": -1.0, "fadh2_m": 1.0}, "id": "RMC0094", "gene_reaction_rule": "(WBGene00020812 or WBGene00019406 or WBGene00020366 or WBGene00017125) and (WBGene00001153 or WBGene00007130) and (WBGene00012177 or WBGene00011467) and ((WBGene00001155 or WBGene00001156) or (WBGene00020347 or WBGene00001150) or WBGene00001152) and ((WBGene00020347 or WBGene00001150) or (WBGene00007129 or WBGene00010035 or WBGene00001157 or WBGene00001158 or WBGene00019978)) and (WBGene00015125 or WBGene00009952)"}, {"subsystem": "Mitochondrial fatty acid beta oxidation", "name": "Beta oxidation of arachidonic acid (mitochondrial)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R00392", "R03224", "R02685", "R01778", "R00391"], "ec-code": ["1.3.8.7", "5.3.3.8", "4.2.1.17", "1.1.1.211", "1.1.1.35", "2.3.1.16"], "sbo": "SBO:0000176"}, "metabolites": {"fa16p3n6coa_m": 1.0, "h2o_m": -2.0, "fad_m": -1.0, "accoa_m": 2.0, "nadh_m": 2.0, "arachdcoa_m": -1.0, "nad_m": -2.0, "coa_m": -2.0, "h_m": 2.0, "fadh2_m": 1.0}, "id": "RMC0095", "gene_reaction_rule": "(WBGene00020812 or WBGene00019406 or WBGene00020366 or WBGene00017125) and (WBGene00001153 or WBGene00007130) and ((WBGene00001155 or WBGene00001156) or (WBGene00020347 or WBGene00001150) or WBGene00001152) and ((WBGene00020347 or WBGene00001150) or (WBGene00007129 or WBGene00010035 or WBGene00001157 or WBGene00001158 or WBGene00019978)) and (WBGene00015125 or WBGene00009952)"}, {"subsystem": "Transport", "name": "(S)-3-Hydroxybutanoate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"S3hb_c": 1.0, "S3hb_e": -1.0}, "id": "TCE0670", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Thiosulfate and Sodium transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"tsul_e": -1.0, "na1_c": 3.0, "tsul_c": 1.0, "na1_e": -3.0}, "id": "TCE0673", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Pyruvate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"pyr_c": 1.0, "pyr_e": -1.0}, "id": "TCE0674", "gene_reaction_rule": ""}, {"subsystem": "Cysteine and methionine metabolism", "name": "o-acetylserine transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"acser_c": 1.0, "acser_e": -1.0}, "id": "TCE5008", "gene_reaction_rule": ""}, {"subsystem": "Valine, leucine and isoleucine degradation", "name": "3-Methylbutanoyl-CoA:(acceptor) 2,3-oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R04095", "ec-code": "1.3.8.4", "sbo": "SBO:0000176"}, "metabolites": {"etfrd_m": 1.0, "etfox_m": -1.0, "3mb2coa_m": 1.0, "ivcoa_m": -1.0}, "id": "RM04096", "gene_reaction_rule": "WBGene00015326"}, {"subsystem": "Terpenoid backbone biosynthesis", "name": "S-Adenosyl-L-methionine:protein-C-terminal-S-geranylgeranyl-L-cysteine O-methyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "2.1.1.100", "sbo": "SBO:0000176"}, "metabolites": {"amet_c": -1.0, "ahcys_c": 1.0, "h_c": 1.0, "protSgerC_c": -1.0, "protSgerCmet_c": 1.0}, "id": "RCC0034", "gene_reaction_rule": "WBGene00017673 or WBGene00019710"}, {"subsystem": "Exchange with the environment", "name": "Nicotinate D-ribonucleotide exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"nicrnt_e": -1.0}, "id": "EX01185", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "4-Trimethylammoniobutanoate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"4tmeabutn_e": -1.0}, "id": "EX01181", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "L-Asparagine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"asn-L_c": 1.0, "asn-L_e": -1.0}, "id": "TCE1211", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Procollagen 5-hydroxy-L-lysine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"pcollg5hlys_e": -1.0}, "id": "EX01211", "gene_reaction_rule": ""}, {"subsystem": "Oxidative phosphorylation", "name": "Ferrocytochrome-c:oxygen oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00081", "ec-code": "1.9.3.1", "sbo": "SBO:0000176"}, "metabolites": {"h2o_m": 2.0, "o2_m": -1.0, "ficytC_m": 4.0, "h_c": 4.0, "h_m": -8.0, "focytC_m": -4.0}, "id": "RM00081", "gene_reaction_rule": "(WBGene00010964 and WBGene00010965 and WBGene00010962) and WBGene00000371 and WBGene00012553 and WBGene00006519 and WBGene00022170 and WBGene00017926 and WBGene00009161 and WBGene00012354 and (WBGene00017121 or WBGene00013854)"}, {"subsystem": "Glycerophospholipid metabolism", "name": "Phosphatidylglycerophosphate phosphohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02029", "ec-code": "3.1.3.27", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "pi_c": 1.0, "pglyc_c": 1.0, "pgp_c": -1.0}, "id": "RC02029", "gene_reaction_rule": ""}, {"subsystem": "Fatty acid metabolism", "name": "Palmitoyl-CoA:oxygen 2-oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01282", "ec-code": ["1.3.8.7", "1.3.8.9"], "sbo": "SBO:0000176"}, "metabolites": {"hdd2coa_m": 1.0, "etfox_m": -1.0, "pmtcoa_m": -1.0, "etfrd_m": 1.0}, "id": "RM01282", "gene_reaction_rule": "(WBGene00020812 or WBGene00019406 or WBGene00020366) or WBGene00017125"}, {"subsystem": "Pyrimidine metabolism", "name": "2-Deoxycytidine diphosphate:oxidized-thioredoxin 2-oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02024", "ec-code": "1.17.4.1", "sbo": "SBO:0000176"}, "metabolites": {"cdp_c": -1.0, "h2o_c": 1.0, "trdox_c": 1.0, "trdrd_c": -1.0, "dcdp_c": 1.0}, "id": "RC02024", "gene_reaction_rule": "WBGene00004391 and WBGene00004392 and (WBGene00017610 or WBGene00019055)"}, {"subsystem": "Ether lipid metabolism", "name": "Acyl-CoA:1-alkyl-sn-glycero-3-phosphate 2-O-acyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R04361", "ec-code": "2.3.1.-", "sbo": "SBO:0000176"}, "metabolites": {"akac2gp_c": 1.0, "coa_c": 1.0, "akgp_c": -1.0, "Rtotal6coa_c": -1.0}, "id": "RC04361", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Lactate and urate transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"lac-L_e": 1.0, "lac-L_c": -1.0, "urate_e": -1.0, "urate_c": 1.0}, "id": "TCE5417", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "L-3-Amino-isobutanoate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"3aib_c": 1.0, "3aib_e": -1.0}, "id": "TCE5416", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Xanthosine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"xtsn_e": -1.0, "xtsn_c": 1.0}, "id": "TCE5414", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "tetradecanoate (n-C14:0) transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"ttdca_e": -1.0, "ttdca_c": 1.0}, "id": "TCE5413", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Thymidine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"thymd_e": -1.0, "thymd_c": 1.0}, "id": "TCE5412", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "(S)-3-Methyl-2-oxopentanoate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"3mop_c": 1.0, "3mop_e": -1.0}, "id": "TCE5358", "gene_reaction_rule": ""}, {"subsystem": "One carbon pool by folate", "name": "5-methyltetrahydrofolate:NAD+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R07168", "ec-code": "1.5.1.20", "sbo": "SBO:0000176"}, "metabolites": {"nad_c": 1.0, "nadh_c": -1.0, "h_c": -2.0, "mlthf_c": -1.0, "5mthf_c": 1.0}, "id": "RC07168", "gene_reaction_rule": "WBGene00015512"}, {"subsystem": "Transport", "name": "Tyramine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"tym_e": 1.0, "tym_c": -1.0}, "id": "TCE5354", "gene_reaction_rule": ""}, {"subsystem": "Amino sugar and nucleotide sugar metabolism", "name": "UDP-N-acetyl-D-glucosamine:chitin 4-beta-N-acetylglucosaminyl-transferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02335", "ec-code": "2.4.1.16", "sbo": "SBO:0000176"}, "metabolites": {"uacgam_c": -1.0, "chitin_c": 1.0, "udp_c": 1.0, "h_c": 1.0}, "id": "RC02335", "gene_reaction_rule": "WBGene00000496 or WBGene00000497"}, {"subsystem": "Transport", "name": "Anthranilate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"anth_c": 1.0, "anth_e": -1.0}, "id": "TCE5356", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "N-Carbamoyl-beta-alanine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"cala_e": -1.0, "cala_c": 1.0}, "id": "TCE5357", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "4-Trimethylammoniobutanoate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"na1_c": -1.0, "4tmeabutn_c": -1.0, "4tmeabutn_e": 1.0, "na1_e": 1.0}, "id": "TCE5350", "gene_reaction_rule": ""}, {"subsystem": "Pyrimidine metabolism", "name": "ATP:dUDP phosphotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R02331", "ec-code": "2.7.4.6", "sbo": "SBO:0000176"}, "metabolites": {"dutp_c": 1.0, "dudp_c": -1.0, "atp_c": -1.0, "adp_c": 1.0}, "id": "RC02331", "gene_reaction_rule": "WBGene00019899 or WBGene00021692 or WBGene00009119"}, {"subsystem": "Transport", "name": "4-Acetamidobutanoate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"4aabutn_e": -1.0, "4aabutn_c": 1.0}, "id": "TCE5352", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Ethanolamine phosphate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"ethamp_e": -1.0, "ethamp_c": 1.0}, "id": "TCE5353", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "2-Phenylacetamide exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"pad_e": -1.0}, "id": "EX02505", "gene_reaction_rule": ""}, {"subsystem": "Biosynthesis of unsaturated fatty acids", "name": "Stearoyl-CoA thioesterase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R08174", "ec-code": "3.1.2.2", "sbo": "SBO:0000176"}, "metabolites": {"stcoa_c": -1.0, "h2o_c": -1.0, "coa_c": 1.0, "h_c": 1.0, "ocdca_c": 1.0}, "id": "RC08174", "gene_reaction_rule": " WBGene00019404 or (WBGene00020989 or WBGene00020258) or WBGene00007857 or (WBGene00015887  or WBGene00015889  or WBGene00016511  or WBGene00017781) "}, {"subsystem": "Biosynthesis of unsaturated fatty acids", "name": "Linoleoyl-CoA hydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R08177", "ec-code": "3.1.2.2", "sbo": "SBO:0000176"}, "metabolites": {"h_c": 1.0, "h2o_c": -1.0, "coa_c": 1.0, "lnlc_c": 1.0, "lnlccoa_c": -1.0}, "id": "RC08177", "gene_reaction_rule": " WBGene00019404 or (WBGene00020989 or WBGene00020258) or WBGene00007857 or (WBGene00015887  or WBGene00015889  or WBGene00016511  or WBGene00017781) "}, {"subsystem": "Pyrimidine metabolism", "name": "ATP:pseudouridine 5'-phosphotransferase; pseudouridine kinase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03315", "ec-code": "2.7.1.83", "sbo": "SBO:0000176"}, "metabolites": {"psduri_c": -1.0, "psd5p_c": 1.0, "adp_c": 1.0, "atp_c": -1.0, "h_c": 1.0}, "id": "RC03315", "gene_reaction_rule": "WBGene00020765"}, {"subsystem": "Iron metabolism", "name": "Cytochrome c apocytochrome-c-lyase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R02480", "ec-code": "4.4.1.17", "sbo": "SBO:0000176"}, "metabolites": {"pheme_m": -1.0, "apocytc_m": -1.0, "focytC_m": 1.0}, "id": "RM02480", "gene_reaction_rule": "WBGene00011527 and (WBGene00017121 or WBGene00013854)"}, {"subsystem": "Lysine degradation", "name": "Glutaryl-CoA:(acceptor) 2,3-oxidoreductase (decarboxylating)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02488", "ec-code": "1.3.8.6", "sbo": "SBO:0000176"}, "metabolites": {"b2coa_m": 1.0, "etfox_m": -1.0, "co2_m": 1.0, "h_m": -1.0, "glutcoa_m": -1.0, "etfrd_m": 1.0}, "id": "RM02488", "gene_reaction_rule": "WBGene00010052"}, {"subsystem": "Transport", "name": "NMN transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"nmn_e": -1.0, "nmn_c": 1.0}, "id": "TCE1158", "gene_reaction_rule": ""}, {"subsystem": "Taurine and hypotaurine metabolism", "name": "sulfinic acid oxidation", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"3sala_m": -1.0, "h_m": -1.0, "h2o_m": 1.0, "Lcyst_m": 1.0, "h2o2_m": -1.0}, "id": "RMC0074", "gene_reaction_rule": ""}, {"subsystem": "Reactive oxygen species degradation", "name": "thioredoxin peroxidase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "1.11.1.15", "sbo": "SBO:0000176"}, "metabolites": {"trdox_m": 1.0, "trdrd_m": -1.0, "h2o_m": 2.0, "h2o2_m": -1.0}, "id": "RMC0075", "gene_reaction_rule": "WBGene00006434 or WBGene00011110"}, {"subsystem": "Sulfur metabolism", "name": "Sulfide:quinone oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "1.8.5.-", "sbo": "SBO:0000176"}, "metabolites": {"h2s_m": -1.0, "q_m": -1.0, "s_m": 1.0, "qh2_m": 1.0}, "id": "RMC0077", "gene_reaction_rule": "WBGene00008538"}, {"subsystem": "Vitamin B6 metabolism", "name": "ATP:pyridoxal 5-phosphotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00174", "ec-code": "2.7.1.35", "sbo": "SBO:0000176"}, "metabolites": {"h_c": 1.0, "pydx5p_c": 1.0, "pydx_c": -1.0, "atp_c": -1.0, "adp_c": 1.0}, "id": "RC00174", "gene_reaction_rule": "WBGene00019008"}, {"subsystem": "Exchange with the environment", "name": "Peptidyl-L-lysine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"peplys_e": -1.0}, "id": "EX02188", "gene_reaction_rule": ""}, {"subsystem": "Pyruvate metabolism", "name": "Lactaldehyde:NAD+ 1-oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R02531", "ec-code": "1.1.1.21", "sbo": "SBO:0000176"}, "metabolites": {"lald-D_c": -1.0, "nadh_c": 1.0, "mthgxl_c": 1.0, "nad_c": -1.0, "h_c": 1.0}, "id": "RC02531", "gene_reaction_rule": "WBGene00012722"}, {"subsystem": "Nicotinate and nicotinamide metabolism", "name": "ATP:nicotinamide-nucleotide adenylyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R03005", "ec-code": ["2.7.7.1", "2.7.7.18"], "sbo": "SBO:0000176"}, "metabolites": {"nicrnt_c": -1.0, "dnad_c": 1.0, "ppi_c": 1.0, "h_c": -1.0, "atp_c": -1.0}, "id": "RC03005", "gene_reaction_rule": "WBGene00012295 or WBGene00009176"}, {"subsystem": "Nicotinate and nicotinamide metabolism", "name": "Deaminido NAD diphosphatase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03004", "ec-code": "3.6.1.9", "sbo": "SBO:0000176"}, "metabolites": {"nicrnt_c": 1.0, "dnad_c": -1.0, "h2o_c": -1.0, "amp_c": 1.0, "h_c": 2.0}, "id": "RC03004", "gene_reaction_rule": "WBGene00007753 or WBGene00007755"}, {"subsystem": "Butanoate metabolism (indirect)", "name": "(S) 3-hydroxybutyryl-CoA hydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "3.1.2.4", "sbo": "SBO:0000176"}, "metabolites": {"S3hb_c": 1.0, "3hbcoa_c": -1.0, "coa_c": 1.0, "h2o_c": -1.0, "h_c": 1.0}, "id": "RCC0134", "gene_reaction_rule": "WBGene00017301"}, {"subsystem": "Histone modification", "name": "Acetyl-CoA:histone acetyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R03552", "ec-code": "2.3.1.48", "sbo": "SBO:0000176"}, "metabolites": {"Naclys_c": 1.0, "coa_c": 1.0, "Nlys_c": -1.0, "accoa_c": -1.0, "h_c": 1.0}, "id": "RC03552", "gene_reaction_rule": "((WBGene00008209 or WBGene00000366) or WBGene00045419 or WBGene00007029 or WBGene00020596 or WBGene00044069 or WBGene00014123 or WBGene00010537 or WBGene00021636) or WBGene00007914"}, {"subsystem": "Transport", "name": "3-Methylimidazoleacetic acid transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"3mlda_e": 1.0, "3mlda_c": -1.0}, "id": "TCE0416", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Taurine and Sodium transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"taur_e": -1.0, "na1_c": 2.0, "taur_c": 1.0, "na1_e": -2.0}, "id": "TCE0417", "gene_reaction_rule": ""}, {"subsystem": "Metal detoxification", "name": "Glutathione:poly(4-glutamyl-cysteinyl)glycine 4-glutamylcysteinyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R03956", "ec-code": "2.3.2.15", "sbo": "SBO:0000176"}, "metabolites": {"pchltn_c": 1.0, "gthrd_c": -1.0, "gly_c": 1.0}, "id": "RC03956", "gene_reaction_rule": "WBGene00003960"}, {"subsystem": "Tryptophan metabolism", "name": "xanthurenate formation", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03954", "sbo": "SBO:0000176"}, "metabolites": {"42A3HP24DB_c": -1.0, "h2o_c": 1.0, "xanate_c": 1.0, "h_c": 1.0}, "id": "RC03954", "gene_reaction_rule": ""}, {"subsystem": "N-Glycan biosynthesis", "name": "glycoprotein 6-alpha-L-fucosyltransferase (acting on nm2masn)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R09319", "ec-code": "2.4.1.68", "sbo": "SBO:0000176"}, "metabolites": {"h_c": 1.0, "gdpfuc_c": -1.0, "fnm2masn_c": 1.0, "nm2masn_c": -1.0, "gdp_c": 1.0}, "id": "RC09319", "gene_reaction_rule": "WBGene00001508"}, {"subsystem": "Peroxisomal fatty acid beta oxidation", "name": "Octanoyl-CoA:acetyl-CoA C-acyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03778", "ec-code": "2.3.1.16", "sbo": "SBO:0000176"}, "metabolites": {"occoa_c": 1.0, "3odcoa_c": -1.0, "coa_c": -1.0, "accoa_c": 1.0}, "id": "RC03778", "gene_reaction_rule": "WBGene00013284"}, {"subsystem": "Exchange with the environment", "name": "Dihydroxyacetone phosphate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"dhap_e": -1.0}, "id": "EX00111", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Folate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"fol_e": -1.0}, "id": "EX00504", "gene_reaction_rule": ""}, {"subsystem": "Butanoate metabolism", "name": "2-Hydroxyglutarate:(acceptor) 2-oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": ["R03534", "R10575"], "ec-code": ["1.1.99.2", "1.1.99.39"], "sbo": "SBO:0000176"}, "metabolites": {"2hglut_m": -1.0, "fad_m": -1.0, "fadh2_m": 1.0, "akg_m": 1.0}, "id": "RM03534", "gene_reaction_rule": "WBGene00021564 or WBGene00010055"}, {"subsystem": "Pyrimidine metabolism", "name": "5,6-Dihydrouracil:NADP+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00978", "ec-code": "1.3.1.2", "sbo": "SBO:0000176"}, "metabolites": {"ura_c": 1.0, "nadp_c": -1.0, "nadph_c": 1.0, "56dura_c": -1.0, "h_c": 1.0}, "id": "RC00978", "gene_reaction_rule": "WBGene00016103"}, {"subsystem": "Glycine, serine and threonine metabolism", "name": "choline:acceptor 1-oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01025", "ec-code": "1.1.99.1", "sbo": "SBO:0000176"}, "metabolites": {"fad_m": -1.0, "betald_m": 1.0, "fadh2_m": 1.0, "chol_m": -1.0}, "id": "RM01025", "gene_reaction_rule": "WBGene00007917"}, {"subsystem": "Arginine and proline metabolism", "name": "L-erythro-4-hydroxyglutamate:2-oxoglutarate aminotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R05052", "ec-code": "2.6.1.1", "sbo": "SBO:0000176"}, "metabolites": {"4h2oglt_m": 1.0, "glu-L_m": 1.0, "e4hglu_m": -1.0, "akg_m": -1.0}, "id": "RM05052", "gene_reaction_rule": "WBGene00016652 or WBGene00015778"}, {"subsystem": "Arginine and proline metabolism", "name": "L-erythro-4-Hydroxyglutamate:NAD+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R05051", "ec-code": "1.2.1.88", "sbo": "SBO:0000176"}, "metabolites": {"4hglusa_m": -1.0, "h2o_m": -1.0, "e4hglu_m": 1.0, "nadh_m": 1.0, "nad_m": -1.0, "h_m": 2.0}, "id": "RM05051", "gene_reaction_rule": "WBGene00000112"}, {"subsystem": "Lysine degradation", "name": "N6-(L-1,3-Dicarboxypropyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00716", "ec-code": "1.5.1.8", "sbo": "SBO:0000176"}, "metabolites": {"saccrp-L_m": 1.0, "nadph_m": -1.0, "h2o_m": 1.0, "nadp_m": 1.0, "akg_m": -1.0, "h_m": -1.0, "lys-L_m": -1.0}, "id": "RM00716", "gene_reaction_rule": "WBGene00019819"}, {"subsystem": "Alanine, aspartate and glutamate metabolism", "name": "Succinate-semialdehyde:NAD+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00713", "ec-code": "1.2.1.24", "sbo": "SBO:0000176"}, "metabolites": {"sucsal_m": -1.0, "h2o_m": -1.0, "nadh_m": 1.0, "nad_m": -1.0, "h_m": 2.0, "succ_m": 1.0}, "id": "RM00713", "gene_reaction_rule": "WBGene00000113"}, {"subsystem": "Glycolysis / Gluconeogenesis", "name": "Acetaldehyde:NAD+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00710", "ec-code": "1.2.1.3", "sbo": "SBO:0000176"}, "metabolites": {"acald_m": -1.0, "h2o_m": -1.0, "ac_m": 1.0, "nadh_m": 1.0, "nad_m": -1.0, "h_m": 2.0}, "id": "RM00710", "gene_reaction_rule": "(WBGene00000107 or WBGene00000108 or WBGene00000110) or WBGene00000115"}, {"subsystem": "Glycolysis / Gluconeogenesis", "name": "Acetaldehyde:NADP+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00711", "ec-code": "1.2.1.5", "sbo": "SBO:0000176"}, "metabolites": {"acald_m": -1.0, "nadph_m": 1.0, "h2o_m": -1.0, "nadp_m": -1.0, "ac_m": 1.0, "h_m": 2.0}, "id": "RM00711", "gene_reaction_rule": "WBGene00000111"}, {"subsystem": "Ascaroside biosynthesis", "name": "Ascarylose synthesis ", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R00956", "R02426", "R03392", "R08708", "R08709"], "ec-code": ["2.7.7.33", "4.2.1.45", "1.17.1.1", "5.1.3.-", "1.1.1.-"], "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": 1.0, "pi_c": 2.0, "nadph_c": -1.0, "g1p_c": -1.0, "nadp_c": 1.0, "h_c": -2.0, "nad_c": 1.0, "ctp_c": -1.0, "nadh_c": -1.0, "cdpascl_c": 1.0}, "id": "RCC0200", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "5-Formyltetrahydrofolate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"5fthf_e": -1.0}, "id": "EX03479", "gene_reaction_rule": ""}, {"subsystem": "Ascaroside biosynthesis", "name": "ascr3 synthesis", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "ascr10coa_c": -1.0, "ascr3coa_c": 1.0, "h2o2_c": 1.0}, "id": "RCC0207", "gene_reaction_rule": "WBGene00008564 or WBGene00008567"}, {"subsystem": "Ascaroside biosynthesis", "name": "ascr1 synthesis", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "accoa_c": 1.0, "ascr1coa_c": 1.0, "ascr3coa_c": -1.0, "coa_c": -1.0, "h_c": 1.0, "nad_c": -1.0, "nadh_c": 1.0}, "id": "RCC0206", "gene_reaction_rule": "WBGene00017123 and WBGene00000991 and WBGene00013284"}, {"subsystem": "Transport", "name": "\"5,10-Methylenetetrahydrofolate\" transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"mlthf_m": 1.0, "mlthf_c": -1.0}, "id": "TCM1069", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Glycolaldehyde transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"gcald_m": 1.0, "gcald_c": -1.0}, "id": "TCM1062", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Indole-3-acetaldehyde transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"id3acald_m": 1.0, "id3acald_c": -1.0}, "id": "TCM1063", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Indole-3-acetate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"ind3ac_m": 1.0, "ind3ac_c": -1.0}, "id": "TCM1061", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "S-Adenosyl-L-methionine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"amet_c": -1.0, "amet_m": 1.0}, "id": "TCM1067", "gene_reaction_rule": ""}, {"subsystem": "Tyrosine metabolism", "name": "4-(2-Aminoethyl)-1,2-benzenediol:oxygen oxidoreductase(deaminating)(flavin-containing)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R04300", "ec-code": "1.4.3.4", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "h2o_c": -1.0, "dopa_c": -1.0, "34dhpac_c": 1.0, "h2o2_c": 1.0, "nh4_c": 1.0}, "id": "RC04300", "gene_reaction_rule": "WBGene00000138"}, {"subsystem": "Fatty acid elongation", "name": "myristoyl-CoA:acetylCoA C-myristoyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R03991", "ec-code": "2.3.1.16", "sbo": "SBO:0000176"}, "metabolites": {"3ohdcoa_m": -1.0, "accoa_m": 1.0, "coa_m": -1.0, "tdcoa_m": 1.0}, "id": "RM03991", "gene_reaction_rule": "WBGene00015125 or WBGene00009952"}, {"subsystem": "Fatty acid metabolism", "name": "Tetradecanoyl-CoA:(acceptor) 2,3-oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R03990", "ec-code": ["1.3.8.7", "1.3.8.9"], "sbo": "SBO:0000176"}, "metabolites": {"tdcoa_m": -1.0, "td2coa_m": 1.0, "etfox_m": -1.0, "etfrd_m": 1.0}, "id": "RM03990", "gene_reaction_rule": "(WBGene00020812 or WBGene00019406 or WBGene00020366) or WBGene00017125"}, {"subsystem": "Glycolysis / Gluconeogenesis", "name": "beta-D-Fructose 1,6-bisphosphate 1-phosphohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R04780", "ec-code": "3.1.3.11", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "pi_c": 1.0, "fdp_c": -1.0, "f6p_c": 1.0}, "id": "RC04780", "gene_reaction_rule": "WBGene00001404"}, {"subsystem": "Carnitine shuttle", "name": "Acyl-CoA:L-carnitine O-acyltransferase I (Tetradecanoyl-CoA )", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "2.3.1.21", "sbo": "SBO:0000176"}, "metabolites": {"crn_c": -1.0, "ttdcrn_c": 1.0, "coa_c": 1.0, "tdcoa_c": -1.0}, "id": "RCC0115", "gene_reaction_rule": "WBGene00012907 or WBGene00021703 or WBGene00019644 or WBGene00008629 or WBGene00020911"}, {"subsystem": "Carnitine shuttle", "name": "Acyl-CoA:L-carnitine O-acyltransferase I (fatty acyl [C20:4]-CoA)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "2.3.1.21", "sbo": "SBO:0000176"}, "metabolites": {"crn_c": -1.0, "arachdcoa_c": -1.0, "coa_c": 1.0, "arachdcrn_c": 1.0}, "id": "RCC0114", "gene_reaction_rule": "WBGene00012907 or WBGene00021703 or WBGene00019644 or WBGene00008629 or WBGene00020911"}, {"subsystem": "Carnitine shuttle", "name": "Acyl-CoA:L-carnitine O-acyltransferase I (Palmitoleyl-CoA)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "2.3.1.21", "sbo": "SBO:0000176"}, "metabolites": {"crn_c": -1.0, "coa_c": 1.0, "fa16p1n7crn_c": 1.0, "fa16p1n7coa_c": -1.0}, "id": "RCC0117", "gene_reaction_rule": "WBGene00012907 or WBGene00021703 or WBGene00019644 or WBGene00008629 or WBGene00020911"}, {"subsystem": "Tryptophan metabolism", "name": "2-aminomuconate reductase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01938", "ec-code": "1.5.1.-", "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": -1.0, "nadp_c": 1.0, "2oxoadp_c": 1.0, "amuco_c": -1.0, "h_c": -1.0, "nadph_c": -1.0, "nh4_c": 1.0}, "id": "RC01938", "gene_reaction_rule": ""}, {"subsystem": "Pyrimidine metabolism", "name": "ATP:UDP phosphotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00156", "ec-code": "2.7.4.6", "sbo": "SBO:0000176"}, "metabolites": {"utp_c": 1.0, "udp_c": -1.0, "adp_c": 1.0, "atp_c": -1.0}, "id": "RC00156", "gene_reaction_rule": "WBGene00019899 or WBGene00021692 or WBGene00009119"}, {"subsystem": "Carnitine shuttle", "name": "Acyl-CoA:L-carnitine O-acyltransferase I (linoleic CoA)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "2.3.1.21", "sbo": "SBO:0000176"}, "metabolites": {"crn_c": -1.0, "lnlccrn_c": 1.0, "coa_c": 1.0, "lnlccoa_c": -1.0}, "id": "RCC0110", "gene_reaction_rule": "WBGene00012907 or WBGene00021703 or WBGene00019644 or WBGene00008629 or WBGene00020911"}, {"subsystem": "Carnitine shuttle", "name": "Acyl-CoA:L-carnitine O-acyltransferase I (eicosatetranoyl CoA)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "2.3.1.21", "sbo": "SBO:0000176"}, "metabolites": {"crn_c": -1.0, "coa_c": 1.0, "eicostetcrn_c": 1.0, "eicostetcoa_c": -1.0}, "id": "RCC0113", "gene_reaction_rule": "WBGene00012907 or WBGene00021703 or WBGene00019644 or WBGene00008629 or WBGene00020911"}, {"subsystem": "Pyrimidine metabolism", "name": "UDP phosphohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00155", "ec-code": "3.6.1.6", "sbo": "SBO:0000176"}, "metabolites": {"ump_c": 1.0, "h2o_c": -1.0, "pi_c": 1.0, "udp_c": -1.0, "h_c": 1.0}, "id": "RC00155", "gene_reaction_rule": "(WBGene00044355 or WBGene00017244) or WBGene00003254 or WBGene00010697"}, {"subsystem": "Pyrimidine metabolism", "name": "ATP:UMP phosphotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00158", "ec-code": "2.7.4.14", "sbo": "SBO:0000176"}, "metabolites": {"ump_c": -1.0, "udp_c": 1.0, "adp_c": 1.0, "atp_c": -1.0}, "id": "RC00158", "gene_reaction_rule": "WBGene00007812 or WBGene00009575"}, {"subsystem": "Carnitine shuttle", "name": "Acyl-CoA:L-carnitine O-acyltransferase I (cis-9,10-methylenehexadecanoyl-CoA)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "2.3.1.21", "sbo": "SBO:0000176"}, "metabolites": {"crn_c": -1.0, "fa17c9crn_c": 1.0, "fa17c9coa_c": -1.0, "coa_c": 1.0}, "id": "RCC0119", "gene_reaction_rule": "WBGene00012907 or WBGene00021703 or WBGene00019644 or WBGene00008629 or WBGene00020911"}, {"subsystem": "Carnitine shuttle", "name": "Acyl-CoA:L-carnitine O-acyltransferase I (cis-3,4-methylenedecanoyl-CoA)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "2.3.1.21", "sbo": "SBO:0000176"}, "metabolites": {"crn_c": -1.0, "fa11c3coa_c": -1.0, "coa_c": 1.0, "fa11c3crn_c": 1.0}, "id": "RCC0118", "gene_reaction_rule": "WBGene00012907 or WBGene00021703 or WBGene00019644 or WBGene00008629 or WBGene00020911"}, {"subsystem": "Citrate cycle (TCA cycle)", "name": "Succinate:CoA ligase (ADP-forming)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00405", "ec-code": "6.2.1.5", "sbo": "SBO:0000176"}, "metabolites": {"succoa_m": 1.0, "atp_m": -1.0, "pi_m": 1.0, "adp_m": 1.0, "coa_m": -1.0, "succ_m": -1.0}, "id": "RM00405", "gene_reaction_rule": "(WBGene00007350 or WBGene00017759) and WBGene00009812"}, {"subsystem": "Fatty acid metabolism", "name": "(S)-3-Hydroxybutanoyl-CoA:NAD+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01975", "ec-code": "1.1.1.35", "sbo": "SBO:0000176"}, "metabolites": {"nad_m": 1.0, "h_m": -1.0, "3hbcoa_m": 1.0, "nadh_m": -1.0, "aacoa_m": -1.0}, "id": "RM01975", "gene_reaction_rule": "WBGene00007129 or WBGene00010035 or WBGene00001157"}, {"subsystem": "Arginine and proline metabolism", "name": "acetyl-CoA:putrescine N-acetyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01154", "ec-code": "2.3.1.57", "sbo": "SBO:0000176"}, "metabolites": {"ptrc_c": -1.0, "coa_c": 1.0, "h_c": 1.0, "accoa_c": -1.0, "aprut_c": 1.0}, "id": "RC01154", "gene_reaction_rule": "WBGene00008408"}, {"subsystem": "Folate biosynthesis", "name": "polyglutamylated thf demand (cytosol)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"7thf_c": -1.0}, "id": "DMN0046", "gene_reaction_rule": ""}, {"subsystem": "Folate biosynthesis", "name": "polyglutamylated thf demand (mitochondrial)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"7thf_m": -1.0}, "id": "DMN0047", "gene_reaction_rule": ""}, {"subsystem": "Pantothenate and CoA biosynthesis", "name": "coenzyme A demand", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"coa_c": -1.0}, "id": "DMN0044", "gene_reaction_rule": ""}, {"subsystem": "Tryptophan metabolism", "name": "cinnavalininate demand", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"cinnavalininate_c": -1.0}, "id": "DMN0042", "gene_reaction_rule": ""}, {"subsystem": "Tryptophan metabolism", "name": "quinolinate demand", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"quln_c": -1.0}, "id": "DMN0043", "gene_reaction_rule": ""}, {"subsystem": "Tryptophan metabolism", "name": "tryptamine demand", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"trypta_c": -1.0}, "id": "DMN0040", "gene_reaction_rule": ""}, {"subsystem": "Tryptophan metabolism", "name": "kynurenate demand", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"kynate_c": -1.0}, "id": "DMN0041", "gene_reaction_rule": ""}, {"subsystem": "Aminoacyl-tRNA biosynthesis", "name": "L-Threonine:tRNA(Thr) ligase (AMP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03663", "ec-code": "6.1.1.3", "sbo": "SBO:0000176"}, "metabolites": {"ppi_m": 1.0, "thrtrna_m": 1.0, "atp_m": -1.0, "trnathr_m": -1.0, "thr-L_m": -1.0, "amp_m": 1.0}, "id": "RM03663", "gene_reaction_rule": "WBGene00006617"}, {"subsystem": "Aminoacyl-tRNA biosynthesis", "name": "L-Serine:tRNA(Ser) ligase (AMP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03662", "ec-code": "6.1.1.11", "sbo": "SBO:0000176"}, "metabolites": {"ppi_m": 1.0, "atp_m": -1.0, "ser-L_m": -1.0, "trnaser_m": -1.0, "amp_m": 1.0, "sertrna_m": 1.0}, "id": "RM03662", "gene_reaction_rule": "WBGene00005662"}, {"subsystem": "Aminoacyl-tRNA biosynthesis", "name": "L-proline:tRNA(Pro) ligase (AMP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03661", "ec-code": "6.1.1.15", "sbo": "SBO:0000176"}, "metabolites": {"protrna_m": 1.0, "ppi_m": 1.0, "trnapro_m": -1.0, "atp_m": -1.0, "pro-L_m": -1.0, "amp_m": 1.0}, "id": "RM03661", "gene_reaction_rule": "WBGene00004190"}, {"subsystem": "Aminoacyl-tRNA biosynthesis", "name": "L-Phenylalanine:tRNA(Ala) ligase (AMP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03660", "ec-code": "6.1.1.20", "sbo": "SBO:0000176"}, "metabolites": {"ppi_m": 1.0, "atp_m": -1.0, "trnaphe_m": -1.0, "phe-L_m": -1.0, "phetrna_m": 1.0, "amp_m": 1.0}, "id": "RM03660", "gene_reaction_rule": "WBGene00013361"}, {"subsystem": "Miscellaneous", "name": "dihydrobiopterin demand", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000628"}, "metabolites": {"dhbpt_c": -1.0}, "id": "DMN0048", "gene_reaction_rule": ""}, {"subsystem": "Aminoacyl-tRNA biosynthesis", "name": "L-Tryptophan -tRNA(Trp) ligase (AMP-forming)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R03664", "ec-code": "6.1.1.2", "sbo": "SBO:0000176"}, "metabolites": {"trnatrp_m": -1.0, "ppi_m": 1.0, "atp_m": -1.0, "trptrna_m": 1.0, "trp-L_m": -1.0, "amp_m": 1.0}, "id": "RM03664", "gene_reaction_rule": "WBGene00006946"}, {"subsystem": "Glyoxylate and dicarboxylate metabolism", "name": "phosphoglycolate phosphatase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01334", "ec-code": "3.1.3.18", "sbo": "SBO:0000176"}, "metabolites": {"2pglyc_c": -1.0, "h2o_c": -1.0, "glyclt_c": 1.0, "pi_c": 1.0}, "id": "RC01334", "gene_reaction_rule": " WBGene00016892 or WBGene00018424 or WBGene00019604"}, {"subsystem": "Pentose phosphate pathway (indirect)", "name": "ATP:sedoheptulose 7-phosphate", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01844", "ec-code": "2.7.1.14", "sbo": "SBO:0000176"}, "metabolites": {"sedh_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "atp_c": -1.0, "s7p_c": 1.0}, "id": "RC01844", "gene_reaction_rule": "WBGene00012017"}, {"subsystem": "Pentose phosphate pathway (indirect)", "name": "ATP:Sedoheptulose 7-phosphate 1-phosphotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01843", "ec-code": "2.7.1.11", "sbo": "SBO:0000176"}, "metabolites": {"h_c": 1.0, "s17bp_c": 1.0, "s7p_c": -1.0, "atp_c": -1.0, "adp_c": 1.0}, "id": "RC01843", "gene_reaction_rule": "WBGene00008230 or WBGene00022199"}, {"subsystem": "Histone modification", "name": "methylated histone sink", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000632"}, "metabolites": {"Nmelys_c": -1.0}, "id": "SNK0036", "gene_reaction_rule": ""}, {"subsystem": "Biosynthesis of unsaturated fatty acids", "name": "DELTA12-fatty-acid desaturase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "1.14.19.6", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "h2o_c": 2.0, "odecoa_c": -1.0, "ficytb_c": 2.0, "lnlccoa_c": 1.0, "focytb_c": -2.0}, "id": "RCC0061", "gene_reaction_rule": "WBGene00001394"}, {"subsystem": "Sphingolipid metabolism", "name": "sphingolipid delta-4 desaturase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "1.14.-.-", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "h2o_c": 2.0, "crm_ce_c": 1.0, "h_c": -1.0, "nad_c": 1.0, "nadh_c": -1.0, "dhcrm_ce_c": -1.0}, "id": "RCC0060", "gene_reaction_rule": "WBGene00017996 or WBGene00013197"}, {"subsystem": "Biosynthesis of unsaturated fatty acids", "name": "long chain fatty acid elongation (Stearidonoyl-CoA to Icosatetraenoyl-CoA)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R10825", "R10826", "R10827", "R10828"], "ec-code": ["2.3.1.199", "1.1.1.330", "4.2.1.134", "1.3.1.93"], "sbo": "SBO:0000176"}, "metabolites": {"strdnccoa_c": -1.0, "h2o_c": 1.0, "malcoa_c": -1.0, "nadph_c": -2.0, "eicostetcoa_c": 1.0, "nadp_c": 2.0, "coa_c": 1.0, "h_c": -3.0, "co2_c": 1.0}, "id": "RCC0063", "gene_reaction_rule": "(WBGene00001239 or WBGene00001240) and WBGene00002891 and WBGene00020517 and WBGene00000198"}, {"subsystem": "Biosynthesis of unsaturated fatty acids", "name": "OMEGA3-fatty acid desaturase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "1.14.19.-", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "h2o_c": 2.0, "ficytb_c": 2.0, "lnlccoa_c": -1.0, "focytb_c": -2.0, "lnlncacoa_c": 1.0}, "id": "RCC0062", "gene_reaction_rule": "WBGene00001393"}, {"subsystem": "Biosynthesis of unsaturated fatty acids", "name": "DELTA5-fatty-acid desaturase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "1.14.19.-", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "h2o_c": 2.0, "dlnlcgcoa_c": -1.0, "ficytb_c": 2.0, "focytb_c": -2.0, "arachdcoa_c": 1.0}, "id": "RCC0065", "gene_reaction_rule": "WBGene00001396"}, {"subsystem": "Biosynthesis of unsaturated fatty acids", "name": "long chain fatty acid elongation (Linolenoyl-CoA to Eicosatrienoyl-CoA)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": ["R09419", "R10826", "R10827", "R10828"], "ec-code": ["2.3.1.199", "1.1.1.330", "4.2.1.134", "1.3.1.93"], "sbo": "SBO:0000176"}, "metabolites": {"h2o_c": 1.0, "malcoa_c": -1.0, "nadph_c": -2.0, "dlnlcgcoa_c": 1.0, "lnlncgcoa_c": -1.0, "nadp_c": 2.0, "coa_c": 1.0, "h_c": -3.0, "co2_c": 1.0}, "id": "RCC0064", "gene_reaction_rule": "(WBGene00001239 or WBGene00001240) and WBGene00002891 and WBGene00020517 and WBGene00000198"}, {"subsystem": "Biosynthesis of unsaturated fatty acids", "name": "OMEGA3-fatty acid desaturase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "1.14.19.-", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "h2o_c": 2.0, "ficytb_c": 2.0, "tmndnccoa_c": 1.0, "eicostetcoa_c": -1.0, "focytb_c": -2.0}, "id": "RCC0067", "gene_reaction_rule": "WBGene00001393"}, {"subsystem": "Biosynthesis of unsaturated fatty acids", "name": "OMEGA3-fatty acid desaturase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "1.14.19.-", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "h2o_c": 2.0, "dlnlcgcoa_c": -1.0, "ficytb_c": 2.0, "eicostetcoa_c": 1.0, "focytb_c": -2.0}, "id": "RCC0066", "gene_reaction_rule": "WBGene00001393"}, {"subsystem": "Biosynthesis of unsaturated fatty acids", "name": "DELTA9-fatty-acid desaturase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "1.14.19.1", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "h2o_c": 2.0, "ficytb_c": 2.0, "pmtcoa_c": -1.0, "fa16p1n7coa_c": 1.0, "focytb_c": -2.0}, "id": "RCC0069", "gene_reaction_rule": "WBGene00001397"}, {"subsystem": "Biosynthesis of unsaturated fatty acids", "name": "DELTA5-fatty-acid desaturase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"ec-code": "1.14.19.-", "sbo": "SBO:0000176"}, "metabolites": {"o2_c": -1.0, "h2o_c": 2.0, "ficytb_c": 2.0, "tmndnccoa_c": 1.0, "focytb_c": -2.0, "arachdcoa_c": -1.0}, "id": "RCC0068", "gene_reaction_rule": "WBGene00001396"}, {"subsystem": "Nitrogen metabolism", "name": "carbonate hydro-lyase (carbon-dioxide-forming)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R10092", "ec-code": "4.2.1.1", "sbo": "SBO:0000176"}, "metabolites": {"hco3_c": 1.0, "h2o_c": -1.0, "co2_c": -1.0, "h_c": 1.0}, "id": "RC10092", "gene_reaction_rule": "((WBGene00000245 or WBGene00013805) or WBGene00000282 or (WBGene00000281 or WBGene00000283 or WBGene00000284)) or (WBGene00000279 or WBGene00000280)"}, {"subsystem": "Arginine and proline metabolism", "name": "ATP:L-arginine Nomega-phosphotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00554", "ec-code": "2.7.3.3", "sbo": "SBO:0000176"}, "metabolites": {"arg-L_c": -1.0, "argp_c": 1.0, "adp_c": 1.0, "atp_c": -1.0, "h_c": 1.0}, "id": "RC00554", "gene_reaction_rule": "WBGene00009706 or WBGene00021128 or WBGene00013894 or WBGene00017975"}, {"subsystem": "Arginine and Proline metabolism", "name": "L-Arginine amidinohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00551", "ec-code": "3.5.3.1", "sbo": "SBO:0000176"}, "metabolites": {"arg-L_c": -1.0, "urea_c": 1.0, "orn_c": 1.0, "h2o_c": -1.0}, "id": "RC00551", "gene_reaction_rule": "WBGene00020658"}, {"subsystem": "Fructose and mannose metabolism", "name": "L-Fucose Sink", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000632"}, "metabolites": {"fuc-L_c": -1.0}, "id": "SNK0101", "gene_reaction_rule": ""}, {"subsystem": "Arginine and proline metabolism", "name": "Arginone phosphate sink", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000632"}, "metabolites": {"argp_c": -1.0}, "id": "SNK0102", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "FMN and Flavin adenine dinucleotide oxidized transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"fad_m": 1.0, "fmn_m": -1.0, "fmn_c": 1.0, "fad_c": -1.0}, "id": "TCM1080", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "L-Tyrosine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"tyr-L_m": 1.0, "tyr-L_c": -1.0}, "id": "TCM1082", "gene_reaction_rule": ""}, {"subsystem": "Inositol phosphate metabolism", "name": "ATP:1-phosphatidyl-1D-myo-inositol-5-phosphate 4-phosphotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R05803", "ec-code": "2.7.1.149", "sbo": "SBO:0000176"}, "metabolites": {"h_c": 1.0, "pail45p_c": 1.0, "adp_c": 1.0, "atp_c": -1.0, "pail5p_c": -1.0}, "id": "RC05803", "gene_reaction_rule": "WBGene00004088"}, {"subsystem": "Transport", "name": "L-Threonine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"thr-L_c": -1.0, "thr-L_m": 1.0}, "id": "TCM1089", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Uridine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"uri_c": 1.0, "uri_e": -1.0}, "id": "TCE0453", "gene_reaction_rule": ""}, {"subsystem": "Amino sugar and nucleotide sugar metabolism", "name": "ATP:N-acetyl-D-glucosamine 6-phosphotransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01201", "ec-code": "2.7.1.59", "sbo": "SBO:0000176"}, "metabolites": {"acgam_c": -1.0, "acgam6p_c": 1.0, "adp_c": 1.0, "atp_c": -1.0, "h_c": 1.0}, "id": "RC01201", "gene_reaction_rule": "WBGene00021057"}, {"subsystem": "Amino sugar and nucleotide sugar metabolism", "name": "[1,4-(N-Acetyl-beta-D-glucosaminyl)]n glycanohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01206", "ec-code": "3.2.1.14", "sbo": "SBO:0000176"}, "metabolites": {"acgam_c": 1.0, "chitin_c": -1.0, "h2o_c": -1.0}, "id": "RC01206", "gene_reaction_rule": "WBGene00007425 or WBGene00011170 or WBGene00011196 or WBGene00020270 or WBGene00044807 or WBGene00012057 or WBGene00007465 or WBGene00016665 or WBGene00010799 or WBGene00010945 or WBGene00011157 or WBGene00011158 or WBGene00011159 or WBGene00011161 or WBGene00011162 or WBGene00007466 or WBGene00011163 or WBGene00011164 or WBGene00011166 or WBGene00011167 or WBGene00020407 or WBGene00011846 or WBGene00011848 or WBGene00007467 or WBGene00007469 or WBGene00007470 or WBGene00007471 or WBGene00007472 or WBGene00007473 or WBGene00014162 or WBGene00000503 or WBGene00011757 or WBGene00021252 or WBGene00017233 or WBGene00020141"}, {"subsystem": "Ubiquinone and other terpenoid-quinone biosynthesis", "name": "Hydroxylation of 3-Decaprenyl-4-hydroxybenzoate (NAD)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R08770", "sbo": "SBO:0000176"}, "metabolites": {"3npdhb_m": 1.0, "h2o_m": 1.0, "o2_m": -1.0, "3nphb_m": -1.0, "nadh_m": -1.0, "nad_m": 1.0, "h_m": -1.0}, "id": "RM08770", "gene_reaction_rule": ""}, {"subsystem": "Ubiquinone and other terpenoid-quinone biosynthesis", "name": "dihydroxydecaprenylbenzoate methyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R08771", "ec-code": "2.1.1.114", "sbo": "SBO:0000176"}, "metabolites": {"3npdhb_m": -1.0, "h_m": 1.0, "3npdhb_me_m": 1.0, "ahcys_m": 1.0, "amet_m": -1.0}, "id": "RM08771", "gene_reaction_rule": "WBGene00000763"}, {"subsystem": "Ubiquinone and other terpenoid-quinone biosynthesis", "name": "3-Decaprenyl-4-hydroxy-5-methoxybenzoate  decarboxylation", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R08772", "sbo": "SBO:0000176"}, "metabolites": {"3npdhb_me_m": -1.0, "h_m": -1.0, "co2_m": 1.0, "2np6mep_m": 1.0}, "id": "RM08772", "gene_reaction_rule": ""}, {"subsystem": "Ubiquinone and other terpenoid-quinone biosynthesis", "name": "Ubiquinone biosynthesis monooxgenase COQ6", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R08773", "ec-code": "1.14.13.-", "sbo": "SBO:0000176"}, "metabolites": {"2np6mep_m": -1.0, "2np6mobq_m": 1.0, "h2o_m": 1.0, "o2_m": -1.0}, "id": "RM08773", "gene_reaction_rule": "WBGene00000766"}, {"subsystem": "Ubiquinone and other terpenoid-quinone biosynthesis", "name": "Ubiquinone biosynthesis methyltransferase COQ5", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R08774", "ec-code": "2.1.1.201", "sbo": "SBO:0000176"}, "metabolites": {"amet_m": -1.0, "h_m": 1.0, "ahcys_m": 1.0, "2np6mobq_me_m": 1.0, "2np6mobq_m": -1.0}, "id": "RM08774", "gene_reaction_rule": "WBGene00000765"}, {"subsystem": "Ubiquinone and other terpenoid-quinone biosynthesis", "name": "Ubiquinone biosynthesis COQ7", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R08775", "ec-code": "1.14.13.-", "sbo": "SBO:0000176"}, "metabolites": {"h_m": -1.0, "2npmhobq_m": 1.0, "nadph_m": -1.0, "h2o_m": 1.0, "nadp_m": 1.0, "o2_m": -1.0, "2np6mobq_me_m": -1.0}, "id": "RM08775", "gene_reaction_rule": "WBGene00000536"}, {"subsystem": "Transport", "name": "dGTP and dADP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dadp_c": 1.0, "dgtp_c": -1.0, "dgtp_m": 1.0, "dadp_m": -1.0}, "id": "TCM0204", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Phosphate and Fumarate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"pi_c": 1.0, "fum_c": -1.0, "pi_m": -1.0, "fum_m": 1.0}, "id": "TCM0207", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "dTDP and dADP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dadp_c": 1.0, "dtdp_m": 1.0, "dtdp_c": -1.0, "dadp_m": -1.0}, "id": "TCM0206", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "L-Malate and Sulfate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"mal-L_c": -1.0, "so4_c": 1.0, "mal-L_m": 1.0, "so4_m": -1.0}, "id": "TCM0201", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "dUDP and dGTP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dgtp_c": -1.0, "dudp_m": -1.0, "dgtp_m": 1.0, "dudp_c": 1.0}, "id": "TCM0200", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Random peptide (special aminoacid carrier) transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"pepX_e": -1.0, "pepX_c": 1.0}, "id": "TCE2001", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Phosphatidylethanolamine transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"pe_e": -1.0, "h2o_c": -1.0, "atp_c": -1.0, "pe_c": 1.0, "h_c": 1.0, "adp_c": 1.0, "pi_c": 1.0}, "id": "TCE2000", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Histone-L-Lysine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"Nlys_e": -1.0, "Nlys_c": 1.0}, "id": "TCE2003", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Phosphatidylserine transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"h2o_c": -1.0, "ps_e": -1.0, "ps_c": 1.0, "atp_c": -1.0, "h_c": 1.0, "adp_c": 1.0, "pi_c": 1.0}, "id": "TCE2005", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "pyridoxine exchange/defecation", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"pydxn_e": -1.0}, "id": "EX00314", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Iodide and Chloride transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"cl_e": -1.0, "i_e": 2.0, "i_c": -2.0, "cl_c": 1.0}, "id": "TCE0459", "gene_reaction_rule": ""}, {"subsystem": "Glycerophospholipid metabolism", "name": "Acyl-CoA:1-acyl-sn-glycero-3-phosphocholine O-acyltransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R01318", "ec-code": "2.3.1.23", "sbo": "SBO:0000176"}, "metabolites": {"pchol_c": 1.0, "lpchol_c": -1.0, "Rtotal2coa_c": -1.0, "coa_c": 1.0}, "id": "RC01318", "gene_reaction_rule": "WBGene00020115"}, {"subsystem": "Exchange with the environment", "name": "Retinoate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"retn_e": -1.0}, "id": "EX00777", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "5-Amino-1-(5-Phospho-D-ribosyl)imidazole-4-carboxamide exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"aicar_e": -1.0}, "id": "EX04677", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Isocitrate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"icit_e": -1.0}, "id": "EX00311", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Sphingosine 1-phosphate exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"sphs1p_ce_e": -1.0}, "id": "EXC0210", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Sphingosine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"sphings_ce_e": -1.0}, "id": "EXC0211", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "glucocerebroside  exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"gluside_ce_e": -1.0}, "id": "EXC0213", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "galactosyl glucosyl ceramide exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"galgluside_ce_e": -1.0}, "id": "EXC0214", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "globoside  exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"gbside_ce_e": -1.0}, "id": "EXC0216", "gene_reaction_rule": ""}, {"subsystem": "Riboflavin metabolism", "name": "ATP:FMN adenylyltransferase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00161", "ec-code": "2.7.7.2", "sbo": "SBO:0000176"}, "metabolites": {"atp_m": -1.0, "fad_m": 1.0, "fmn_m": -1.0, "h_m": -1.0, "ppi_m": 1.0}, "id": "RM00161", "gene_reaction_rule": "WBGene00011271"}, {"subsystem": "Glycerophospholipid metabolism", "name": "Phosphatidylcholine phosphatidohydrolase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R01310", "ec-code": "3.1.4.4", "sbo": "SBO:0000176"}, "metabolites": {"chol_c": 1.0, "pchol_c": -1.0, "h2o_c": -1.0, "h_c": 1.0, "pa_pl_c": 1.0}, "id": "RC01310", "gene_reaction_rule": "WBGene00004040 or (WBGene00017316 or WBGene00020256 or WBGene00013080)"}, {"subsystem": "Alanine, aspartate and glutamate metabolism", "name": "L-Alanine:glyoxylate aminotransferase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R00369", "ec-code": "2.6.1.44", "sbo": "SBO:0000176"}, "metabolites": {"pyr_m": 1.0, "glx_m": -1.0, "gly_m": 1.0, "ala-L_m": -1.0}, "id": "RM00369", "gene_reaction_rule": "WBGene00020382 or WBGene00011767"}, {"subsystem": "Transport", "name": "L-Aspartate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"asp-L_e": -1.0, "asp-L_c": 1.0}, "id": "TCE1117", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "ADP/ATP Translocase", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"atp_m": -1.0, "adp_m": 1.0, "atp_c": 1.0, "adp_c": -1.0}, "id": "TCM0111", "gene_reaction_rule": "WBGene00006439 or WBGene00007057 or WBGene00010485 or WBGene00020140"}, {"subsystem": "Transport", "name": "dUDP and dCDP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dcdp_m": 1.0, "dudp_m": -1.0, "dudp_c": 1.0, "dcdp_c": -1.0}, "id": "TCM0110", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Glycerol transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"glyc_m": 1.0, "glyc_c": -1.0}, "id": "TCM0113", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "dUTP and ADP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"adp_m": -1.0, "dutp_m": 1.0, "dutp_c": -1.0, "adp_c": 1.0}, "id": "TCM0115", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "dUDP and dGDP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dgdp_c": -1.0, "dudp_m": -1.0, "dgdp_m": 1.0, "dudp_c": 1.0}, "id": "TCM0114", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "L-Leucine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"leu-L_c": -1.0, "leu-L_m": 1.0}, "id": "TCM0117", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "dTTP and dGDP transport", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"dttp_m": 1.0, "dgdp_c": 1.0, "dttp_c": -1.0, "dgdp_m": -1.0}, "id": "TCM0116", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "\"3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestane\" transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"xoltriol_c": -1.0, "xoltriol_m": 1.0}, "id": "TCM0119", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Thiosulfate and Fumarate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"tsul_m": -1.0, "fum_c": -1.0, "tsul_c": 1.0, "fum_m": 1.0}, "id": "TCM0118", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Choline exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"chol_e": -1.0}, "id": "EX00114", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "Glycerol exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"glyc_e": -1.0}, "id": "EX00116", "gene_reaction_rule": ""}, {"subsystem": "Exchange with the environment", "name": "O-Acetyl-L-serine exchange", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"sbo": "SBO:0000627"}, "metabolites": {"acser_e": -1.0}, "id": "EX00979", "gene_reaction_rule": ""}, {"subsystem": "Tryptophan metabolism", "name": "L-tryptophan:oxygen 2,3-oxidoreductase (decyclizing)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R00678", "ec-code": "1.13.11.11", "sbo": "SBO:0000176"}, "metabolites": {"Lfmkynr_c": 1.0, "o2_c": -1.0, "trp-L_c": -1.0}, "id": "RC00678", "gene_reaction_rule": "WBGene00016201"}, {"subsystem": "Transport", "name": "D-Fructose transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"fru_e": -1.0, "fru_c": 1.0}, "id": "TCE0648", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "2-Hydroxybutyrate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"2hb_c": 1.0, "2hb_e": -1.0}, "id": "TCE0644", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "D-Glucosamine 6-phosphate transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"gam6p_c": 1.0, "gam6p_e": -1.0}, "id": "TCE1206", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "Glycolaldehyde transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"gcald_e": -1.0, "gcald_c": 1.0}, "id": "TCE1204", "gene_reaction_rule": ""}, {"subsystem": "Glycerolipid metabolism", "name": "1,2-diacyl-sn-glycerol 3-phosphate phosphohydrolase (acting on phospholipids)", "upper_bound": 1000.0, "lower_bound": -0.0, "annotation": {"kegg.reaction": "R02239", "ec-code": "3.1.3.4", "sbo": "SBO:0000176"}, "metabolites": {"pa_pl_c": -1.0, "h2o_c": -1.0, "pi_c": 1.0, "dag_pl_c": 1.0}, "id": "RC02239", "gene_reaction_rule": "(WBGene00008749 or WBGene00018756 or WBGene00020895) or WBGene00010425"}, {"subsystem": "One carbon pool by folate", "name": "dihydrofolate:NAD+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R02235", "ec-code": "1.5.1.3", "sbo": "SBO:0000176"}, "metabolites": {"nadh_c": -1.0, "fol_c": -1.0, "dhf_c": 1.0, "nad_c": 1.0}, "id": "RC02235", "gene_reaction_rule": "WBGene00007974"}, {"subsystem": "One carbon pool by folate", "name": "dihydrofolate:NADP+ oxidoreductase", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R02236", "ec-code": "1.5.1.3", "sbo": "SBO:0000176"}, "metabolites": {"nadph_c": -1.0, "nadp_c": 1.0, "fol_c": -1.0, "dhf_c": 1.0}, "id": "RC02236", "gene_reaction_rule": "WBGene00007974"}, {"subsystem": "Transport", "name": "L-Arginine transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"arg-L_c": 1.0, "arg-L_e": -1.0}, "id": "TCE1208", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "\"7alpha,12alpha-Dihydroxycholest-4-en-3-one\" transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"xoldiolone_c": 1.0, "xoldiolone_m": -1.0}, "id": "TCM0317", "gene_reaction_rule": ""}, {"subsystem": "Tyrosine metabolism", "name": "melanine biosynthesis (last step)", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"kegg.reaction": "R04886", "sbo": "SBO:0000176"}, "metabolites": {"ind56qn_c": -1.0, "o2_c": -1.0, "h2o_c": 1.0, "eumelanin_c": 1.0}, "id": "RC04886", "gene_reaction_rule": ""}, {"subsystem": "Transport", "name": "27-Hydroxycholesterol transport", "upper_bound": 1000.0, "lower_bound": -1000.0, "annotation": {"sbo": "SBO:0000185"}, "metabolites": {"xol27oh_m": 1.0, "xol27oh_c": -1.0}, "id": "TCM0316", "gene_reaction_rule": ""}], "name": "iCEL1314", "genes": [{"annotation": {"kegg.genes": "CELE_F35H10.4", "wormbase": "WBGene00006914", "sbo": "SBO:0000243", "uniprot": "G5EEK9"}, "name": "vha-5", "id": "WBGene00006914"}, {"annotation": {"kegg.genes": "CELE_T01H3.1", "wormbase": "WBGene00006913", "sbo": "SBO:0000243", "uniprot": "G5EDB8"}, "name": "vha-4", "id": "WBGene00006913"}, {"annotation": {"kegg.genes": "CELE_F45H10.2", "wormbase": "WBGene00009739", "sbo": "SBO:0000243", "uniprot": "O45525"}, "name": "F45H10.2", "id": "WBGene00009739"}, {"annotation": {"kegg.genes": "CELE_F45H10.3", "wormbase": "WBGene00009740", "sbo": "SBO:0000243", "uniprot": "O02267"}, "name": "F45H10.3", "id": "WBGene00009740"}, {"annotation": {"kegg.genes": "CELE_R10E11.8", "wormbase": "WBGene00006910", "sbo": "SBO:0000243", "uniprot": "Q21898"}, "name": "vha-1", "id": "WBGene00006910"}, {"annotation": {"kegg.genes": "CELE_W05E10.4", "wormbase": "WBGene00006609", "sbo": "SBO:0000243", "uniprot": ["F5GUD3", "F5GUD4", "G5EG27"]}, "name": "tre-3", "id": "WBGene00006609"}, {"annotation": {"kegg.genes": "CELE_Y38F2AL.4", "wormbase": "WBGene00006912", "sbo": "SBO:0000243", "uniprot": "P34546"}, "name": "vha-3", "id": "WBGene00006912"}, {"annotation": {"kegg.genes": "CELE_R10E11.2", "wormbase": "WBGene00006911", "sbo": "SBO:0000243", "uniprot": "P34546"}, "name": "vha-2", "id": "WBGene00006911"}, {"annotation": {"kegg.genes": "CELE_C04F12.10", "wormbase": "WBGene00001405", "sbo": "SBO:0000243", "uniprot": "Q9XVE5"}, "name": "fce-1", "id": "WBGene00001405"}, {"annotation": {"kegg.genes": "CELE_T05A12.2", "wormbase": "WBGene00006608", "sbo": "SBO:0000243", "uniprot": "Q9GYK9"}, "name": "tre-2", "id": "WBGene00006608"}, {"annotation": {"kegg.genes": "CELE_ZK970.4", "wormbase": "WBGene00006918", "sbo": "SBO:0000243", "uniprot": "Q23680"}, "name": "vha-9", "id": "WBGene00006918"}, {"annotation": {"kegg.genes": "CELE_C26H9A.1", "wormbase": "WBGene00006916", "sbo": "SBO:0000243", "uniprot": ["B2MZD0", "G5EDH1"]}, "name": "vha-7", "id": "WBGene00006916"}, {"annotation": {"kegg.genes": "CELE_C09E10.2", "wormbase": "WBGene00000958", "sbo": "SBO:0000243", "uniprot": ["Q58AU6", "Q58AU4", "Q17860", "Q7JNZ1", "Q58AU5"]}, "name": "dgk-1", "id": "WBGene00000958"}, {"annotation": {"kegg.genes": "CELE_H17B01.1", "wormbase": "WBGene00019207", "sbo": "SBO:0000243", "uniprot": "O44827"}, "name": "fgt-1", "id": "WBGene00019207"}, {"annotation": {"kegg.genes": "CELE_VW02B12L.1", "wormbase": "WBGene00006915", "sbo": "SBO:0000243", "uniprot": "G5EGP4"}, "name": "vha-6", "id": "WBGene00006915"}, {"annotation": {"kegg.genes": "CELE_ZC416.8b", "wormbase": "WBGene00000481", "sbo": "SBO:0000243", "uniprot": "P32756"}, "name": "cha-1", "id": "WBGene00000481"}, {"annotation": {"kegg.genes": "CELE_C02C2.5", "wormbase": "WBGene00015334", "sbo": "SBO:0000243", "uniprot": "P34273"}, "name": "sup-18", "id": "WBGene00015334"}, {"annotation": {"kegg.genes": "CELE_C36A4.4", "wormbase": "WBGene00007965", "sbo": "SBO:0000243", "uniprot": "Q18493"}, "name": "C36A4.4", "id": "WBGene00007965"}, {"annotation": {"kegg.genes": "CELE_D2023.2", "wormbase": "WBGene00004258", "sbo": "SBO:0000243", "uniprot": ["H2L2E4", "O17732"]}, "name": "pyc-1", "id": "WBGene00004258"}, {"annotation": {"kegg.genes": "CELE_Y39E4A.3", "wormbase": "WBGene00012713", "sbo": "SBO:0000243", "uniprot": ["Q4A1S8", "O45924"]}, "name": "bckd-1A", "id": "WBGene00012713"}, {"annotation": {"kegg.genes": "CELE_C02C2.1", "wormbase": "WBGene00015332", "sbo": "SBO:0000243", "uniprot": "P34269"}, "name": "tyr-1", "id": "WBGene00015332"}, {"annotation": {"kegg.genes": "CELE_R04F11.2", "wormbase": "WBGene00011015", "sbo": "SBO:0000243", "uniprot": "Q21732"}, "name": "R04F11.2", "id": "WBGene00011015"}, {"annotation": {"kegg.genes": "CELE_F25H9.6", "wormbase": "WBGene00009138", "sbo": "SBO:0000243", "uniprot": "P91988"}, "name": "F25H9.6", "id": "WBGene00009138"}, {"annotation": {"kegg.genes": "CELE_M01E11.1", "wormbase": "WBGene00019710", "sbo": "SBO:0000243", "uniprot": "P91402"}, "name": "M01E11.1", "id": "WBGene00019710"}, {"annotation": {"kegg.genes": "CELE_Y24D9A.8", "wormbase": "WBGene00021286", "sbo": "SBO:0000243", "uniprot": ["Q966C7", "Q8T876"]}, "name": "tald-1", "id": "WBGene00021286"}, {"annotation": {"kegg.genes": "CELE_C47B2.2", "wormbase": "WBGene00008131", "sbo": "SBO:0000243", "uniprot": "Q9U3L5"}, "name": "C47B2.2", "id": "WBGene00008131"}, {"annotation": {"kegg.genes": "CELE_ZK673.2", "wormbase": "WBGene00014058", "sbo": "SBO:0000243", "uniprot": "Q09629"}, "name": "ZK673.2", "id": "WBGene00014058"}, {"annotation": {"kegg.genes": "CELE_F22B5.9", "wormbase": "WBGene00001498", "sbo": "SBO:0000243", "uniprot": "Q19713"}, "name": "fars-3", "id": "WBGene00001498"}, {"annotation": {"kegg.genes": "CELE_C31H2.4", "wormbase": "WBGene00016294", "sbo": "SBO:0000243", "uniprot": "Q18347"}, "name": "C31H2.4", "id": "WBGene00016294"}, {"annotation": {"kegg.genes": "CELE_E02H1.6", "wormbase": "WBGene00008458", "sbo": "SBO:0000243", "uniprot": "Q09527"}, "name": "E02H1.6", "id": "WBGene00008458"}, {"annotation": {"kegg.genes": "CELE_T25C8.1", "wormbase": "WBGene00012017", "sbo": "SBO:0000243", "uniprot": "O45814"}, "name": "T25C8.1", "id": "WBGene00012017"}, {"annotation": {"kegg.genes": "CELE_Y73B6BL.1", "wormbase": "WBGene00022231", "sbo": "SBO:0000243", "uniprot": "Q95XC6"}, "name": "tyr-6", "id": "WBGene00022231"}, {"annotation": {"kegg.genes": "CELE_Y49C4A.8", "wormbase": "WBGene00021709", "sbo": "SBO:0000243", "uniprot": ["Q86S69", "H2L0C9"]}, "name": "ugt-29", "id": "WBGene00021709"}, {"annotation": {"kegg.genes": "CELE_R07H5.8", "wormbase": "WBGene00011128", "sbo": "SBO:0000243", "uniprot": "Q93934"}, "name": "R07H5.8", "id": "WBGene00011128"}, {"annotation": {"kegg.genes": "CELE_ZC395.2", "wormbase": "WBGene00000536", "sbo": "SBO:0000243", "uniprot": "P48376"}, "name": "clk-1", "id": "WBGene00000536"}, {"annotation": {"kegg.genes": "CELE_C10H11.3", "wormbase": "WBGene00015692", "sbo": "SBO:0000243", "uniprot": "P91039"}, "name": "ugt-25", "id": "WBGene00015692"}, {"annotation": {"kegg.genes": "CELE_T01D1.4", "wormbase": "WBGene00020149", "sbo": "SBO:0000243", "uniprot": "P91416"}, "name": "T01D1.4", "id": "WBGene00020149"}, {"annotation": {"kegg.genes": "CELE_C10H11.5", "wormbase": "WBGene00015694", "sbo": "SBO:0000243", "uniprot": "P91037"}, "name": "ugt-27", "id": "WBGene00015694"}, {"annotation": {"kegg.genes": "CELE_C10H11.6", "wormbase": "WBGene00015695", "sbo": "SBO:0000243", "uniprot": ["B1Q250", "H2KYQ0"]}, "name": "ugt-26", "id": "WBGene00015695"}, {"annotation": {"kegg.genes": "CELE_C33A12.6", "wormbase": "WBGene00007885", "sbo": "SBO:0000243", "uniprot": "Q18361"}, "name": "ugt-21", "id": "WBGene00007885"}, {"annotation": {"kegg.genes": "CELE_K08B4.4", "wormbase": "WBGene00019516", "sbo": "SBO:0000243", "uniprot": "Q9TYY4"}, "name": "ugt-20", "id": "WBGene00019516"}, {"annotation": {"kegg.genes": "CELE_F08F8.2", "wormbase": "WBGene00017268", "sbo": "SBO:0000243", "uniprot": "Q19207"}, "name": "hmgr-1", "id": "WBGene00017268"}, {"annotation": {"kegg.genes": "CELE_C08F11.8", "wormbase": "WBGene00007455", "sbo": "SBO:0000243", "uniprot": "Q9U3Q6"}, "name": "ugt-22", "id": "WBGene00007455"}, {"annotation": {"kegg.genes": "CELE_F48A11.1", "wormbase": "WBGene00000497", "sbo": "SBO:0000243", "uniprot": "G5EBQ8"}, "name": "chs-2", "id": "WBGene00000497"}, {"annotation": {"kegg.genes": "CELE_T25G3.2", "wormbase": "WBGene00000496", "sbo": "SBO:0000243", "uniprot": "G5ECD6"}, "name": "chs-1", "id": "WBGene00000496"}, {"annotation": {"kegg.genes": "CELE_C14E2.4", "wormbase": "WBGene00015773", "sbo": "SBO:0000243", "uniprot": "Q17985"}, "name": "C14E2.4", "id": "WBGene00015773"}, {"annotation": {"kegg.genes": "CELE_C53B4.7", "wormbase": "WBGene00000266", "sbo": "SBO:0000243", "uniprot": "Q18801"}, "name": "bre-1", "id": "WBGene00000266"}, {"annotation": {"kegg.genes": "CELE_Y5H2B.5", "wormbase": "WBGene00021167", "sbo": "SBO:0000243", "uniprot": "Q9N4Q5"}, "name": "cyp-32B1", "id": "WBGene00021167"}, {"annotation": {"kegg.genes": "CELE_T21B10.2", "wormbase": "WBGene00011884", "sbo": "SBO:0000243", "uniprot": "Q27527"}, "name": "enol-1", "id": "WBGene00011884"}, {"annotation": {"kegg.genes": "CELE_F28G4.1", "wormbase": "WBGene00009226", "sbo": "SBO:0000243", "uniprot": "O17851"}, "name": "cyp-37B1", "id": "WBGene00009226"}, {"annotation": {"kegg.genes": "CELE_LLC1.3", "wormbase": "WBGene00010794", "sbo": "SBO:0000243", "uniprot": "O17953"}, "name": "dld-1", "id": "WBGene00010794"}, {"annotation": {"kegg.genes": "CELE_T06E8.1", "wormbase": "WBGene00011543", "sbo": "SBO:0000243", "uniprot": ["I2HA82", "Q22267"]}, "name": "acl-2", "id": "WBGene00011543"}, {"annotation": {"kegg.genes": "CELE_F08F3.4", "wormbase": "WBGene00017262", "sbo": "SBO:0000243", "uniprot": "Q22945"}, "name": "F08F3.4", "id": "WBGene00017262"}, {"annotation": {"kegg.genes": "CELE_K07B1.4", "wormbase": "WBGene00019464", "sbo": "SBO:0000243", "uniprot": ["Q86FS9", "O01881"]}, "name": "K07B1.4", "id": "WBGene00019464"}, {"annotation": {"kegg.genes": "CELE_C17H12.14", "wormbase": "WBGene00006917", "sbo": "SBO:0000243", "uniprot": "Q95X44"}, "name": "vha-8", "id": "WBGene00006917"}, {"annotation": {"kegg.genes": "CELE_F48E3.1", "wormbase": "WBGene00001637", "sbo": "SBO:0000243", "uniprot": ["G5EBG7", "Q8MQ38"]}, "name": "gly-12", "id": "WBGene00001637"}, {"annotation": {"kegg.genes": "CELE_F53F1.2", "wormbase": "WBGene00009980", "sbo": "SBO:0000243", "uniprot": "P91997"}, "name": "F53F1.2", "id": "WBGene00009980"}, {"annotation": {"kegg.genes": "CELE_W03G1.7", "wormbase": "WBGene00000213", "sbo": "SBO:0000243", "uniprot": ["Q9UAY4", "G8JY85"]}, "name": "asm-3", "id": "WBGene00000213"}, {"annotation": {"kegg.genes": "CELE_ZK455.4", "wormbase": "WBGene00000212", "sbo": "SBO:0000243", "uniprot": "Q23498"}, "name": "asm-2", "id": "WBGene00000212"}, {"annotation": {"kegg.genes": "CELE_B0252.2", "wormbase": "WBGene00000211", "sbo": "SBO:0000243", "uniprot": "Q10916"}, "name": "asm-1", "id": "WBGene00000211"}, {"annotation": {"kegg.genes": "CELE_T01G1.4", "wormbase": "WBGene00044025", "sbo": "SBO:0000243", "uniprot": "Q5FC21"}, "name": "T01G1.4", "id": "WBGene00044025"}, {"annotation": {"kegg.genes": "CELE_T28D9.3", "wormbase": "WBGene00020895", "sbo": "SBO:0000243", "uniprot": ["Q10022", "H2L0E9", "H2L0F1", "A8WFI4", "H2L0F0"]}, "name": "T28D9.3", "id": "WBGene00020895"}, {"annotation": {"kegg.genes": "CELE_R151.5", "wormbase": "WBGene00006592", "sbo": "SBO:0000243", "uniprot": "P98060"}, "name": "dpy-31", "id": "WBGene00006592"}, {"annotation": {"kegg.genes": "CELE_W02D9.1", "wormbase": "WBGene00004181", "sbo": "SBO:0000243", "uniprot": ["D7SFP4", "O02334"]}, "name": "pri-2", "id": "WBGene00004181"}, {"annotation": {"kegg.genes": "CELE_F59A1.10", "wormbase": "WBGene00010296", "sbo": "SBO:0000243", "uniprot": "Q9XUW0"}, "name": "dgat-2", "id": "WBGene00010296"}, {"annotation": {"kegg.genes": "CELE_C41G7.4", "wormbase": "WBGene00008062", "sbo": "SBO:0000243", "uniprot": "Q93368"}, "name": "set-32", "id": "WBGene00008062"}, {"annotation": {"kegg.genes": "CELE_Y108F1.3", "wormbase": "WBGene00022431", "sbo": "SBO:0000243", "uniprot": "Q8MXK5"}, "name": "set-33", "id": "WBGene00022431"}, {"annotation": {"kegg.genes": "CELE_C05D11.12", "wormbase": "WBGene00002855", "sbo": "SBO:0000243", "uniprot": "Q11190"}, "name": "let-721", "id": "WBGene00002855"}, {"annotation": {"kegg.genes": "CELE_C54E4.5", "wormbase": "WBGene00016920", "sbo": "SBO:0000243", "uniprot": "Q65CM5"}, "name": "C54E4.5", "id": "WBGene00016920"}, {"annotation": {"kegg.genes": "CELE_H14N18.4", "wormbase": "WBGene00019204", "sbo": "SBO:0000243", "uniprot": ["A8WIT0", "H2L0B7"]}, "name": "H14N18.4", "id": "WBGene00019204"}, {"annotation": {"kegg.genes": "CELE_F41E7.6", "wormbase": "WBGene00009622", "sbo": "SBO:0000243", "uniprot": "Q20278"}, "name": "F41E7.6", "id": "WBGene00009622"}, {"annotation": {"kegg.genes": "CELE_F27D4.5", "wormbase": "WBGene00006518", "sbo": "SBO:0000243", "uniprot": "Q93619"}, "name": "bckd-1B", "id": "WBGene00006518"}, {"annotation": {"kegg.genes": "CELE_Y50D7A.7", "wormbase": "WBGene00000081", "sbo": "SBO:0000243", "uniprot": "O45218"}, "name": "ads-1", "id": "WBGene00000081"}, {"annotation": {"kegg.genes": "CELE_R03D7.1", "wormbase": "WBGene00010988", "sbo": "SBO:0000243", "uniprot": "Q09582"}, "name": "metr-1", "id": "WBGene00010988"}, {"annotation": {"kegg.genes": "CELE_T21C12.2", "wormbase": "WBGene00001993", "sbo": "SBO:0000243", "uniprot": "Q22633"}, "name": "hpd-1", "id": "WBGene00001993"}, {"annotation": {"kegg.genes": "CELE_ZC443.1", "wormbase": "WBGene00013896", "sbo": "SBO:0000243", "uniprot": "Q23320"}, "name": "ZC443.1", "id": "WBGene00013896"}, {"annotation": {"kegg.genes": "CELE_C08B6.4", "wormbase": "WBGene00007425", "sbo": "SBO:0000243", "uniprot": ["Q17816", "Q65ZB0"]}, "name": "C08B6.4", "id": "WBGene00007425"}, {"annotation": {"kegg.genes": "CELE_Y49A3A.1", "wormbase": "WBGene00013024", "sbo": "SBO:0000243", "uniprot": "G5EC25"}, "name": "cept-2", "id": "WBGene00013024"}, {"annotation": {"kegg.genes": "CELE_F25B5.6", "wormbase": "WBGene00017777", "sbo": "SBO:0000243", "uniprot": "Q09509"}, "name": "F25B5.6", "id": "WBGene00017777"}, {"annotation": {"kegg.genes": "CELE_F25B5.3", "wormbase": "WBGene00017775", "sbo": "SBO:0000243", "uniprot": ["G8JY82", "Q09315", "H2KZL8"]}, "name": "F25B5.3", "id": "WBGene00017775"}, {"annotation": {"kegg.genes": "CELE_F23B12.5", "wormbase": "WBGene00009082", "sbo": "SBO:0000243", "uniprot": "Q19749"}, "name": "dlat-1", "id": "WBGene00009082"}, {"annotation": {"kegg.genes": "CELE_C26F1.2", "wormbase": "WBGene00016147", "sbo": "SBO:0000243", "uniprot": "Q27472"}, "name": "cyp-32A1", "id": "WBGene00016147"}, {"annotation": {"kegg.genes": "CELE_F41H10.8", "wormbase": "WBGene00001244", "sbo": "SBO:0000243", "uniprot": "Q20303"}, "name": "elo-6", "id": "WBGene00001244"}, {"annotation": {"kegg.genes": "CELE_D2085.1", "wormbase": "WBGene00004259", "sbo": "SBO:0000243", "uniprot": "Q18990"}, "name": "pyr-1", "id": "WBGene00004259"}, {"annotation": {"kegg.genes": "CELE_F27D4.1", "wormbase": "WBGene00009187", "sbo": "SBO:0000243", "uniprot": "Q93615"}, "name": "F27D4.1", "id": "WBGene00009187"}, {"annotation": {"kegg.genes": "CELE_H12D21.7", "wormbase": "WBGene00010383", "sbo": "SBO:0000243", "uniprot": ["Q9XTW9", "H9G341", "H9G340"]}, "name": "mpst-3", "id": "WBGene00010383"}, {"annotation": {"kegg.genes": "CELE_H12D21.4", "wormbase": "WBGene00010380", "sbo": "SBO:0000243", "uniprot": "Q9XTX2"}, "name": "mpst-2", "id": "WBGene00010380"}, {"annotation": {"kegg.genes": "CELE_T12F5.4", "wormbase": "WBGene00003040", "sbo": "SBO:0000243", "uniprot": "O44757"}, "name": "lin-59", "id": "WBGene00003040"}, {"annotation": {"kegg.genes": "CELE_T19H12.6", "wormbase": "WBGene00020590", "sbo": "SBO:0000243", "uniprot": "O01610"}, "name": "T19H12.6", "id": "WBGene00020590"}, {"annotation": {"kegg.genes": "CELE_R186.6", "wormbase": "WBGene00011307", "sbo": "SBO:0000243", "uniprot": "G5EEV0"}, "name": "mpst-7", "id": "WBGene00011307"}, {"annotation": {"kegg.genes": "CELE_Y59H11AM.3", "wormbase": "WBGene00022007", "sbo": "SBO:0000243", "uniprot": "G5ECA0"}, "name": "mpst-6", "id": "WBGene00022007"}, {"annotation": {"kegg.genes": "CELE_Y59H11AM.2", "wormbase": "WBGene00022006", "sbo": "SBO:0000243", "uniprot": "G5ECA0"}, "name": "mpst-5", "id": "WBGene00022006"}, {"annotation": {"kegg.genes": "CELE_F11G11.9", "wormbase": "WBGene00017387", "sbo": "SBO:0000243", "uniprot": "P91247"}, "name": "mpst-4", "id": "WBGene00017387"}, {"annotation": {"kegg.genes": "CELE_F53A2.8", "wormbase": "WBGene00003478", "sbo": "SBO:0000243", "uniprot": ["Q69Z15", "G5ED68", "G5EBF2"]}, "name": "mtm-6", "id": "WBGene00003478"}, {"annotation": {"kegg.genes": "CELE_C46H11.4", "wormbase": "WBGene00002979", "sbo": "SBO:0000243", "uniprot": ["H2KZ47", "H2KZ46", "H2KZ45", "H2KZ43", "H2KZ42", "Q95Q62"]}, "name": "lfe-2", "id": "WBGene00002979"}, {"annotation": {"kegg.genes": "CELE_T24A11.1", "wormbase": "WBGene00003476", "sbo": "SBO:0000243", "uniprot": "Q22712"}, "name": "mtm-3", "id": "WBGene00003476"}, {"annotation": {"kegg.genes": "CELE_Y110A7A.5", "wormbase": "WBGene00003475", "sbo": "SBO:0000243", "uniprot": "Q9N589"}, "name": "mtm-1", "id": "WBGene00003475"}, {"annotation": {"kegg.genes": "CELE_W08D2.4", "wormbase": "WBGene00001395", "sbo": "SBO:0000243", "uniprot": "Q23221"}, "name": "fat-3", "id": "WBGene00001395"}, {"annotation": {"kegg.genes": "CELE_W02A2.1", "wormbase": "WBGene00001394", "sbo": "SBO:0000243", "uniprot": "G5EGA5"}, "name": "fat-2", "id": "WBGene00001394"}, {"annotation": {"kegg.genes": "CELE_Y67H2A.8", "wormbase": "WBGene00001393", "sbo": "SBO:0000243", "uniprot": "Q9NEQ0"}, "name": "fat-1", "id": "WBGene00001393"}, {"annotation": {"kegg.genes": "CELE_C01G6.6", "wormbase": "WBGene00006510", "sbo": "SBO:0000243", "uniprot": "Q17574"}, "name": "mtrr-1", "id": "WBGene00006510"}, {"annotation": {"kegg.genes": "CELE_F10D2.9", "wormbase": "WBGene00001399", "sbo": "SBO:0000243", "uniprot": "G5EGH6"}, "name": "fat-7", "id": "WBGene00001399"}, {"annotation": {"kegg.genes": "CELE_VZK822L.1", "wormbase": "WBGene00001398", "sbo": "SBO:0000243", "uniprot": "G5EGN2"}, "name": "fat-6", "id": "WBGene00001398"}, {"annotation": {"kegg.genes": "CELE_W06D12.3", "wormbase": "WBGene00001397", "sbo": "SBO:0000243", "uniprot": "G5ED44"}, "name": "fat-5", "id": "WBGene00001397"}, {"annotation": {"kegg.genes": "CELE_T13F2.1", "wormbase": "WBGene00001396", "sbo": "SBO:0000243", "uniprot": "G5EG11"}, "name": "fat-4", "id": "WBGene00001396"}, {"annotation": {"kegg.genes": "CELE_T26F2.1", "wormbase": "WBGene00012057", "sbo": "SBO:0000243", "uniprot": "G5EDK9"}, "name": "T26F2.1", "id": "WBGene00012057"}, {"annotation": {"kegg.genes": "CELE_B0280.1", "wormbase": "WBGene00015099", "sbo": "SBO:0000243", "uniprot": "P41992"}, "name": "ggtb-1", "id": "WBGene00015099"}, {"annotation": {"kegg.genes": "CELE_ZK524.3", "wormbase": "WBGene00003074", "sbo": "SBO:0000243", "uniprot": ["G5EBH2", "Q23511", "B3WFV4"]}, "name": "lars-2", "id": "WBGene00003074"}, {"annotation": {"kegg.genes": "CELE_T13A10.11", "wormbase": "WBGene00006416", "sbo": "SBO:0000243", "uniprot": "Q27522"}, "name": "sams-5", "id": "WBGene00006416"}, {"annotation": {"kegg.genes": "CELE_C06E7.3", "wormbase": "WBGene00015540", "sbo": "SBO:0000243", "uniprot": "P50306"}, "name": "sams-4", "id": "WBGene00015540"}, {"annotation": {"kegg.genes": "CELE_R04F11.3", "wormbase": "WBGene00011016", "sbo": "SBO:0000243", "uniprot": "Q21730"}, "name": "R04F11.3", "id": "WBGene00011016"}, {"annotation": {"kegg.genes": "CELE_C47E12.8", "wormbase": "WBGene00000964", "sbo": "SBO:0000243", "uniprot": "Q18677"}, "name": "dhp-2", "id": "WBGene00000964"}, {"annotation": {"kegg.genes": "CELE_K12G11.4", "wormbase": "WBGene00010791", "sbo": "SBO:0000243", "uniprot": "O45687"}, "name": "sodh-2", "id": "WBGene00010791"}, {"annotation": {"kegg.genes": "CELE_K12G11.3", "wormbase": "WBGene00010790", "sbo": "SBO:0000243", "uniprot": "Q17334"}, "name": "sodh-1", "id": "WBGene00010790"}, {"annotation": {"kegg.genes": "CELE_R06C7.3", "wormbase": "WBGene00000963", "sbo": "SBO:0000243", "uniprot": "Q21773"}, "name": "dhp-1", "id": "WBGene00000963"}, {"annotation": {"kegg.genes": "CELE_R10D12.15", "wormbase": "WBGene00011196", "sbo": "SBO:0000243", "uniprot": "G5EDK9"}, "name": "R10D12.15", "id": "WBGene00011196"}, {"annotation": {"kegg.genes": "CELE_Y51H7C.9", "wormbase": "WBGene00021787", "sbo": "SBO:0000243", "uniprot": "Q95XY8"}, "name": "Y51H7C.9", "id": "WBGene00021787"}, {"annotation": {"kegg.genes": "CELE_Y46G5A.19", "wormbase": "WBGene00012909", "sbo": "SBO:0000243", "uniprot": ["G5EFG3", "B4E3X6"]}, "name": "spds-1", "id": "WBGene00012909"}, {"annotation": {"kegg.genes": "CELE_F42G8.12", "wormbase": "WBGene00002162", "sbo": "SBO:0000243", "uniprot": "O44512"}, "name": "isp-1", "id": "WBGene00002162"}, {"annotation": {"kegg.genes": "CELE_F10F2.2", "wormbase": "WBGene00008654", "sbo": "SBO:0000243", "uniprot": "Q19311"}, "name": "F10F2.2", "id": "WBGene00008654"}, {"annotation": {"kegg.genes": "CELE_C31H5.6", "wormbase": "WBGene00007857", "sbo": "SBO:0000243", "uniprot": ["B3WFZ4", "B3WFZ3"]}, "name": "C31H5.6", "id": "WBGene00007857"}, {"annotation": {"kegg.genes": "CELE_F01G4.2", "wormbase": "WBGene00000181", "sbo": "SBO:0000243", "uniprot": "Q19102"}, "name": "ard-1", "id": "WBGene00000181"}, {"annotation": {"kegg.genes": "CELE_W06H3.3", "wormbase": "WBGene00012316", "sbo": "SBO:0000243", "uniprot": "G5EC98"}, "name": "ctps-1", "id": "WBGene00012316"}, {"annotation": {"kegg.genes": "CELE_T24C4.5", "wormbase": "WBGene00020761", "sbo": "SBO:0000243", "uniprot": "Q9TZ34"}, "name": "T24C4.5", "id": "WBGene00020761"}, {"annotation": {"kegg.genes": "CELE_Y46G5A.5", "wormbase": "WBGene00012897", "sbo": "SBO:0000243", "uniprot": "Q9U2G1"}, "name": "pisy-1", "id": "WBGene00012897"}, {"annotation": {"kegg.genes": "CELE_ZK1290.2", "wormbase": "WBGene00006600", "sbo": "SBO:0000243", "uniprot": ["G5EED8", "Q2V4U7"]}, "name": "tph-1", "id": "WBGene00006600"}, {"annotation": {"kegg.genes": "CELE_F14F4.3", "wormbase": "WBGene00003411", "sbo": "SBO:0000243", "uniprot": ["G5EEY4", "G5EE72"]}, "name": "mrp-5", "id": "WBGene00003411"}, {"annotation": {"kegg.genes": "CELE_Y48G10A.1", "wormbase": "WBGene00013018", "sbo": "SBO:0000243", "uniprot": "G5EF86"}, "name": "Y48G10A.1", "id": "WBGene00013018"}, {"annotation": {"kegg.genes": "CELE_D2013.5", "wormbase": "WBGene00001134", "sbo": "SBO:0000243", "uniprot": "Q18965"}, "name": "eat-3", "id": "WBGene00001134"}, {"annotation": {"kegg.genes": "CELE_ZK637.9", "wormbase": "WBGene00014027", "sbo": "SBO:0000243", "uniprot": "P30636"}, "name": "tpk-1", "id": "WBGene00014027"}, {"annotation": {"kegg.genes": "CELE_B0365.3", "wormbase": "WBGene00001137", "sbo": "SBO:0000243", "uniprot": "P90735"}, "name": "eat-6", "id": "WBGene00001137"}, {"annotation": {"kegg.genes": "CELE_K01C8.1", "wormbase": "WBGene00010456", "sbo": "SBO:0000243", "uniprot": "Q21080"}, "name": "K01C8.1", "id": "WBGene00010456"}, {"annotation": {"kegg.genes": "CELE_F29F11.1", "wormbase": "WBGene00005022", "sbo": "SBO:0000243", "uniprot": "Q19905"}, "name": "sqv-4", "id": "WBGene00005022"}, {"annotation": {"kegg.genes": "CELE_E01A2.1", "wormbase": "WBGene00017084", "sbo": "SBO:0000243", "uniprot": ["A9CZN9", "Q966L2"]}, "name": "E01A2.1", "id": "WBGene00017084"}, {"annotation": {"kegg.genes": "CELE_B0331.1", "wormbase": "WBGene00007140", "sbo": "SBO:0000243", "uniprot": "O45219"}, "name": "cyp-29A4", "id": "WBGene00007140"}, {"annotation": {"kegg.genes": "CELE_C47B2.6", "wormbase": "WBGene00008132", "sbo": "SBO:0000243", "uniprot": ["O62107", "Q564Q1"]}, "name": "gale-1", "id": "WBGene00008132"}, {"annotation": {"kegg.genes": "CELE_W06E11.1", "wormbase": "WBGene00021061", "sbo": "SBO:0000243", "uniprot": "Q23206"}, "name": "W06E11.1", "id": "WBGene00021061"}, {"annotation": {"kegg.genes": "CELE_T24C12.3", "wormbase": "WBGene00020765", "sbo": "SBO:0000243", "uniprot": "Q22721"}, "name": "T24C12.3", "id": "WBGene00020765"}, {"annotation": {"kegg.genes": "CELE_R06A4.8", "wormbase": "WBGene00011050", "sbo": "SBO:0000243", "uniprot": "O62334"}, "name": "agl-1", "id": "WBGene00011050"}, {"annotation": {"kegg.genes": "CELE_ZC8.6", "wormbase": "WBGene00022501", "sbo": "SBO:0000243", "uniprot": "Q23083"}, "name": "ZC8.6", "id": "WBGene00022501"}, {"annotation": {"kegg.genes": "CELE_F54D5.12", "wormbase": "WBGene00010055", "sbo": "SBO:0000243", "uniprot": "G5EE46"}, "name": "F54D5.12", "id": "WBGene00010055"}, {"annotation": {"kegg.genes": "CELE_W06B4.2", "wormbase": "WBGene00021057", "sbo": "SBO:0000243", "uniprot": "Q23195"}, "name": "W06B4.2", "id": "WBGene00021057"}, {"annotation": {"kegg.genes": "CELE_K10C2.4", "wormbase": "WBGene00019620", "sbo": "SBO:0000243", "uniprot": "Q94272"}, "name": "fah-1", "id": "WBGene00019620"}, {"annotation": {"kegg.genes": "CELE_F20H11.3", "wormbase": "WBGene00003162", "sbo": "SBO:0000243", "uniprot": "O02640"}, "name": "mdh-2", "id": "WBGene00003162"}, {"annotation": {"kegg.genes": "CELE_F14B4.2", "wormbase": "WBGene00008780", "sbo": "SBO:0000243", "uniprot": ["Q6BET1", "Q19440"]}, "name": "hxk-1", "id": "WBGene00008780"}, {"annotation": {"kegg.genes": "CELE_C14B9.2", "wormbase": "WBGene00015752", "sbo": "SBO:0000243", "uniprot": "P34329"}, "name": "C14B9.2", "id": "WBGene00015752"}, {"annotation": {"kegg.genes": "CELE_Y77E11A.1", "wormbase": "WBGene00022306", "sbo": "SBO:0000243", "uniprot": "Q9N4A5"}, "name": "hxk-3", "id": "WBGene00022306"}, {"annotation": {"kegg.genes": "CELE_H25P06.1", "wormbase": "WBGene00010416", "sbo": "SBO:0000243", "uniprot": "Q9XU15"}, "name": "hxk-2", "id": "WBGene00010416"}, {"annotation": {"kegg.genes": "CELE_ZK1058.1", "wormbase": "WBGene00014202", "sbo": "SBO:0000243", "uniprot": "Q23381"}, "name": "mmcm-1", "id": "WBGene00014202"}, {"annotation": {"kegg.genes": "CELE_ZC513.4", "wormbase": "WBGene00006935", "sbo": "SBO:0000243", "uniprot": "Q23360"}, "name": "vars-1", "id": "WBGene00006935"}, {"annotation": {"kegg.genes": "CELE_C24A11.9", "wormbase": "WBGene00000761", "sbo": "SBO:0000243", "uniprot": "P91093"}, "name": "coq-1", "id": "WBGene00000761"}, {"annotation": {"kegg.genes": "CELE_Y57G11C.11", "wormbase": "WBGene00000763", "sbo": "SBO:0000243", "uniprot": "O18235"}, "name": "coq-3", "id": "WBGene00000763"}, {"annotation": {"kegg.genes": "CELE_F57B9.4", "wormbase": "WBGene00000762", "sbo": "SBO:0000243", "uniprot": ["Q8I7J3", "Q8I7J2", "Q8I7J4", "Q5DX47"]}, "name": "coq-2", "id": "WBGene00000762"}, {"annotation": {"kegg.genes": "CELE_ZK652.9", "wormbase": "WBGene00000765", "sbo": "SBO:0000243", "uniprot": "P34666"}, "name": "coq-5", "id": "WBGene00000765"}, {"annotation": {"kegg.genes": "CELE_K07B1.2", "wormbase": "WBGene00000766", "sbo": "SBO:0000243", "uniprot": "O01884"}, "name": "coq-6", "id": "WBGene00000766"}, {"annotation": {"kegg.genes": "CELE_C14C11.3", "wormbase": "WBGene00015767", "sbo": "SBO:0000243", "uniprot": "G5EFL1"}, "name": "hex-2", "id": "WBGene00015767"}, {"annotation": {"kegg.genes": "CELE_B0280.3", "wormbase": "WBGene00015101", "sbo": "SBO:0000243", "uniprot": "P41994"}, "name": "rpia-1", "id": "WBGene00015101"}, {"annotation": {"kegg.genes": "CELE_T15H9.6", "wormbase": "WBGene00011791", "sbo": "SBO:0000243", "uniprot": "Q09995"}, "name": "T15H9.6", "id": "WBGene00011791"}, {"annotation": {"kegg.genes": "CELE_T04A8.5", "wormbase": "WBGene00011407", "sbo": "SBO:0000243", "uniprot": "Q22134"}, "name": "ppat-1", "id": "WBGene00011407"}, {"annotation": {"kegg.genes": "CELE_F42F12.4", "wormbase": "WBGene00009636", "sbo": "SBO:0000243", "uniprot": "Q20340"}, "name": "F42F12.4", "id": "WBGene00009636"}, {"annotation": {"kegg.genes": "CELE_Y76A2B.3", "wormbase": "WBGene00013575", "sbo": "SBO:0000243", "uniprot": "Q9XWD1"}, "name": "acs-5", "id": "WBGene00013575"}, {"annotation": {"kegg.genes": "CELE_F54D5.1", "wormbase": "WBGene00003960", "sbo": "SBO:0000243", "uniprot": ["A5JYS0", "A5JYS1"]}, "name": "pcs-1", "id": "WBGene00003960"}, {"annotation": {"kegg.genes": "CELE_Y53G8AL.2", "wormbase": "WBGene00021800", "sbo": "SBO:0000243", "uniprot": "Q9N3H3"}, "name": "Y53G8AL.2", "id": "WBGene00021800"}, {"annotation": {"kegg.genes": "CELE_T07F10.1", "wormbase": "WBGene00011587", "sbo": "SBO:0000243", "uniprot": ["Q22317", "Q1HB04"]}, "name": "T07F10.1", "id": "WBGene00011587"}, {"annotation": {"kegg.genes": "CELE_C17F4.6", "wormbase": "WBGene00001544", "sbo": "SBO:0000243", "uniprot": "O16544"}, "name": "gcy-19", "id": "WBGene00001544"}, {"annotation": {"kegg.genes": "CELE_ZK896.8", "wormbase": "WBGene00001543", "sbo": "SBO:0000243", "uniprot": "G5EFQ0"}, "name": "gcy-18", "id": "WBGene00001543"}, {"annotation": {"kegg.genes": "CELE_T12B3.3", "wormbase": "WBGene00020446", "sbo": "SBO:0000243", "uniprot": "Q9UAW8"}, "name": "T12B3.3", "id": "WBGene00020446"}, {"annotation": {"kegg.genes": "CELE_Y39G8B.1", "wormbase": "WBGene00012722", "sbo": "SBO:0000243", "uniprot": ["Q9U2J6", "Q9NAI5"]}, "name": "Y39G8B.1", "id": "WBGene00012722"}, {"annotation": {"kegg.genes": "CELE_Y39G8B.2", "wormbase": "WBGene00012723", "sbo": "SBO:0000243", "uniprot": "Q9U2J5"}, "name": "Y39G8B.2", "id": "WBGene00012723"}, {"annotation": {"kegg.genes": "CELE_ZK643.2", "wormbase": "WBGene00014034", "sbo": "SBO:0000243", "uniprot": "P30648"}, "name": "ZK643.2", "id": "WBGene00014034"}, {"annotation": {"kegg.genes": "CELE_F08B1.2", "wormbase": "WBGene00001538", "sbo": "SBO:0000243", "uniprot": "Q19187"}, "name": "gcy-12", "id": "WBGene00001538"}, {"annotation": {"kegg.genes": "CELE_ZC239.7", "wormbase": "WBGene00001541", "sbo": "SBO:0000243", "uniprot": "P91550"}, "name": "gcy-15", "id": "WBGene00001541"}, {"annotation": {"kegg.genes": "CELE_ZC412.2", "wormbase": "WBGene00001540", "sbo": "SBO:0000243"}, "name": "gcy-14", "id": "WBGene00001540"}, {"annotation": {"kegg.genes": "CELE_W03F11.2", "wormbase": "WBGene00001542", "sbo": "SBO:0000243"}, "name": "gcy-17", "id": "WBGene00001542"}, {"annotation": {"kegg.genes": "CELE_T02H6.11", "wormbase": "WBGene00020181", "sbo": "SBO:0000243", "uniprot": "Q9N5E4"}, "name": "T02H6.11", "id": "WBGene00020181"}, {"annotation": {"kegg.genes": "CELE_C34E10.6", "wormbase": "WBGene00000229", "sbo": "SBO:0000243", "uniprot": "P46561"}, "name": "atp-2", "id": "WBGene00000229"}, {"annotation": {"kegg.genes": "CELE_C04F5.7", "wormbase": "WBGene00015449", "sbo": "SBO:0000243", "uniprot": "Q9GZD1"}, "name": "ugt-63", "id": "WBGene00015449"}, {"annotation": {"kegg.genes": "CELE_T22F3.3", "wormbase": "WBGene00020696", "sbo": "SBO:0000243", "uniprot": ["Q9N5U1", "Q86NC1"]}, "name": "T22F3.3", "id": "WBGene00020696"}, {"annotation": {"kegg.genes": "CELE_F08G5.5", "wormbase": "WBGene00008583", "sbo": "SBO:0000243", "uniprot": "Q19222"}, "name": "ugt-65", "id": "WBGene00008583"}, {"annotation": {"kegg.genes": "ATP6", "wormbase": "WBGene00010960", "sbo": "SBO:0000243", "uniprot": ["P24888", "G5EFS7"]}, "name": "atp-6", "id": "WBGene00010960"}, {"annotation": {"kegg.genes": "CELE_C06H2.1", "wormbase": "WBGene00007385", "sbo": "SBO:0000243", "uniprot": "Q17763"}, "name": "atp-5", "id": "WBGene00007385"}, {"annotation": {"kegg.genes": "CELE_F57B10.3", "wormbase": "WBGene00019001", "sbo": "SBO:0000243", "uniprot": ["Q8IA68", "G5EFZ1"]}, "name": "ipgm-1", "id": "WBGene00019001"}, {"annotation": {"kegg.genes": "CELE_C27A2.12", "wormbase": "WBGene00206373", "sbo": "SBO:0000243", "uniprot": "E7EM30"}, "name": "C27A2.12", "id": "WBGene00206373"}, {"annotation": {"kegg.genes": "CELE_M01D7.4", "wormbase": "WBGene00006461", "sbo": "SBO:0000243", "uniprot": "O01969"}, "name": "tag-96", "id": "WBGene00006461"}, {"annotation": {"kegg.genes": "CELE_C34B2.8", "wormbase": "WBGene00016393", "sbo": "SBO:0000243", "uniprot": "O44955"}, "name": "C34B2.8", "id": "WBGene00016393"}, {"annotation": {"kegg.genes": "CELE_C52E4.5", "wormbase": "WBGene00008258", "sbo": "SBO:0000243", "uniprot": "Q18788"}, "name": "mans-2", "id": "WBGene00008258"}, {"annotation": {"kegg.genes": "CELE_T03G11.4", "wormbase": "WBGene00020197", "sbo": "SBO:0000243", "uniprot": "Q22120"}, "name": "mans-3", "id": "WBGene00020197"}, {"annotation": {"kegg.genes": "CELE_D2030.1", "wormbase": "WBGene00008411", "sbo": "SBO:0000243", "uniprot": "P90787"}, "name": "mans-1", "id": "WBGene00008411"}, {"annotation": {"kegg.genes": "CELE_F54C1.1", "wormbase": "WBGene00018789", "sbo": "SBO:0000243", "uniprot": "P91326"}, "name": "F54C1.1", "id": "WBGene00018789"}, {"annotation": {"kegg.genes": "CELE_F26D11.1", "wormbase": "WBGene00017818", "sbo": "SBO:0000243", "uniprot": "O61968"}, "name": "F26D11.1", "id": "WBGene00017818"}, {"annotation": {"kegg.genes": "CELE_R134.2", "wormbase": "WBGene00001529", "sbo": "SBO:0000243", "uniprot": "Q10029"}, "name": "gcy-2", "id": "WBGene00001529"}, {"annotation": {"kegg.genes": "CELE_C53D5.5", "wormbase": "WBGene00016906", "sbo": "SBO:0000243", "uniprot": "Q9N5V4"}, "name": "C53D5.5", "id": "WBGene00016906"}, {"annotation": {"kegg.genes": "CELE_T22D1.3", "wormbase": "WBGene00020682", "sbo": "SBO:0000243", "uniprot": "Q9GZH3"}, "name": "T22D1.3", "id": "WBGene00020682"}, {"annotation": {"kegg.genes": "CELE_E02H9.5", "wormbase": "WBGene00017103", "sbo": "SBO:0000243", "uniprot": "Q9TZA0"}, "name": "klo-2", "id": "WBGene00017103"}, {"annotation": {"kegg.genes": "CELE_H43I07.3", "wormbase": "WBGene00019276", "sbo": "SBO:0000243", "uniprot": "Q8WSL9"}, "name": "H43I07.3", "id": "WBGene00019276"}, {"annotation": {"kegg.genes": "CELE_D2030.5", "wormbase": "WBGene00008415", "sbo": "SBO:0000243", "uniprot": "G5EEG4"}, "name": "mce-1", "id": "WBGene00008415"}, {"annotation": {"kegg.genes": "CELE_C50F7.10", "wormbase": "WBGene00016848", "sbo": "SBO:0000243", "uniprot": "Q18758"}, "name": "klo-1", "id": "WBGene00016848"}, {"annotation": {"kegg.genes": "CELE_W02H5.8", "wormbase": "WBGene00020962", "sbo": "SBO:0000243", "uniprot": "Q9N5C4"}, "name": "W02H5.8", "id": "WBGene00020962"}, {"annotation": {"kegg.genes": "CELE_T26A5.3", "wormbase": "WBGene00006463", "sbo": "SBO:0000243", "uniprot": "Q22800"}, "name": "nduf-2.2", "id": "WBGene00006463"}, {"annotation": {"kegg.genes": "CELE_C23H3.7", "wormbase": "WBGene00006611", "sbo": "SBO:0000243", "uniprot": "G5EG96"}, "name": "tre-5", "id": "WBGene00006611"}, {"annotation": {"kegg.genes": "CELE_F15A2.2", "wormbase": "WBGene00006610", "sbo": "SBO:0000243", "uniprot": "G5EDP3"}, "name": "tre-4", "id": "WBGene00006610"}, {"annotation": {"kegg.genes": "CELE_T25G12.5", "wormbase": "WBGene00020812", "sbo": "SBO:0000243", "uniprot": "Q22781"}, "name": "acdh-7", "id": "WBGene00020812"}, {"annotation": {"kegg.genes": "CELE_T05H4.7", "wormbase": "WBGene00020270", "sbo": "SBO:0000243", "uniprot": "O16512"}, "name": "T05H4.7", "id": "WBGene00020270"}, {"annotation": {"kegg.genes": "CELE_C55B7.4", "wormbase": "WBGene00016943", "sbo": "SBO:0000243", "uniprot": ["H2KZG6", "Q8IAB6"]}, "name": "acdh-1", "id": "WBGene00016943"}, {"annotation": {"kegg.genes": "CELE_F13H8.9", "wormbase": "WBGene00017442", "sbo": "SBO:0000243", "uniprot": "Q19434"}, "name": "F13H8.9", "id": "WBGene00017442"}, {"annotation": {"kegg.genes": "CELE_K06A5.6", "wormbase": "WBGene00019433", "sbo": "SBO:0000243", "uniprot": "O44549"}, "name": "acdh-3", "id": "WBGene00019433"}, {"annotation": {"kegg.genes": "CELE_C17C3.12", "wormbase": "WBGene00015894", "sbo": "SBO:0000243", "uniprot": ["Q9BIB0", "H2KYU0", "H2KYT9"]}, "name": "acdh-2", "id": "WBGene00015894"}, {"annotation": {"kegg.genes": "CELE_F21C3.2", "wormbase": "WBGene00009001", "sbo": "SBO:0000243", "uniprot": "Q19673"}, "name": "tyr-3", "id": "WBGene00009001"}, {"annotation": {"kegg.genes": "CELE_K08E3.1", "wormbase": "WBGene00010661", "sbo": "SBO:0000243", "uniprot": "Q9XUS8"}, "name": "tyr-2", "id": "WBGene00010661"}, {"annotation": {"kegg.genes": "CELE_F54D5.7", "wormbase": "WBGene00010052", "sbo": "SBO:0000243", "uniprot": "Q20772"}, "name": "F54D5.7", "id": "WBGene00010052"}, {"annotation": {"kegg.genes": "CELE_H13N06.3", "wormbase": "WBGene00001649", "sbo": "SBO:0000243", "uniprot": "Q9XTQ5"}, "name": "gob-1", "id": "WBGene00001649"}, {"annotation": {"kegg.genes": "CELE_F28A10.6", "wormbase": "WBGene00017874", "sbo": "SBO:0000243", "uniprot": "Q95YB2"}, "name": "acdh-9", "id": "WBGene00017874"}, {"annotation": {"kegg.genes": "CELE_K05F1.3", "wormbase": "WBGene00019406", "sbo": "SBO:0000243", "uniprot": "Q21243"}, "name": "acdh-8", "id": "WBGene00019406"}, {"annotation": {"kegg.genes": "CELE_Y44E3B.2", "wormbase": "WBGene00021553", "sbo": "SBO:0000243", "uniprot": "O76708"}, "name": "tyr-5", "id": "WBGene00021553"}, {"annotation": {"kegg.genes": "CELE_C34G6.2", "wormbase": "WBGene00016419", "sbo": "SBO:0000243", "uniprot": "O01497"}, "name": "tyr-4", "id": "WBGene00016419"}, {"annotation": {"kegg.genes": "CELE_C31C9.2", "wormbase": "WBGene00007836", "sbo": "SBO:0000243", "uniprot": "O17626"}, "name": "C31C9.2", "id": "WBGene00007836"}, {"annotation": {"kegg.genes": "CELE_T03F1.3", "wormbase": "WBGene00020185", "sbo": "SBO:0000243", "uniprot": "P91427"}, "name": "pgk-1", "id": "WBGene00020185"}, {"annotation": {"kegg.genes": "CELE_T06D8.6", "wormbase": "WBGene00011527", "sbo": "SBO:0000243", "uniprot": "P53703"}, "name": "cchl-1", "id": "WBGene00011527"}, {"annotation": {"kegg.genes": "CELE_T01C8.5", "wormbase": "WBGene00020146", "sbo": "SBO:0000243", "uniprot": "Q22067"}, "name": "got-1.2", "id": "WBGene00020146"}, {"annotation": {"kegg.genes": "CELE_Y45F10D.4", "wormbase": "WBGene00012885", "sbo": "SBO:0000243", "uniprot": "O45948"}, "name": "Y45F10D.4", "id": "WBGene00012885"}, {"annotation": {"kegg.genes": "CELE_C16A3.5", "wormbase": "WBGene00015810", "sbo": "SBO:0000243", "uniprot": "Q18036"}, "name": "C16A3.5", "id": "WBGene00015810"}, {"annotation": {"kegg.genes": "CELE_T28F3.5", "wormbase": "WBGene00012131", "sbo": "SBO:0000243", "uniprot": "C1P655"}, "name": "T28F3.5", "id": "WBGene00012131"}, {"annotation": {"kegg.genes": "CELE_C47A10.5", "wormbase": "WBGene00008127", "sbo": "SBO:0000243", "uniprot": ["O45307", "C8JQS2"]}, "name": "ddo-1", "id": "WBGene00008127"}, {"annotation": {"kegg.genes": "CELE_F54D7.2", "wormbase": "WBGene00018797", "sbo": "SBO:0000243", "uniprot": "O44732"}, "name": "F54D7.2", "id": "WBGene00018797"}, {"annotation": {"kegg.genes": "CELE_F20H11.5", "wormbase": "WBGene00017648", "sbo": "SBO:0000243", "uniprot": "O01739"}, "name": "ddo-3", "id": "WBGene00017648"}, {"annotation": {"kegg.genes": "CELE_F18E3.7", "wormbase": "WBGene00017565", "sbo": "SBO:0000243", "uniprot": "Q19564"}, "name": "ddo-2", "id": "WBGene00017565"}, {"annotation": {"kegg.genes": "CELE_R07E5.2", "wormbase": "WBGene00011110", "sbo": "SBO:0000243", "uniprot": "Q21824"}, "name": "prdx-3", "id": "WBGene00011110"}, {"annotation": {"kegg.genes": "CELE_F09E5.15", "wormbase": "WBGene00006434", "sbo": "SBO:0000243", "uniprot": ["H2KZL7", "Q8IG31"]}, "name": "prdx-2", "id": "WBGene00006434"}, {"annotation": {"kegg.genes": "CELE_C44B7.7", "wormbase": "WBGene00016629", "sbo": "SBO:0000243", "uniprot": "Q18596"}, "name": "C44B7.7", "id": "WBGene00016629"}, {"annotation": {"kegg.genes": "CELE_F47G4.3", "wormbase": "WBGene00009824", "sbo": "SBO:0000243", "uniprot": "Q9XTS4"}, "name": "gpdh-1", "id": "WBGene00009824"}, {"annotation": {"kegg.genes": "CELE_K11H3.1", "wormbase": "WBGene00010778", "sbo": "SBO:0000243", "uniprot": ["P34517", "A7LPE6", "A7LPE5", "Q7JMU1"]}, "name": "gpdh-2", "id": "WBGene00010778"}, {"annotation": {"kegg.genes": "CELE_Y48G8AL.15", "wormbase": "WBGene00021692", "sbo": "SBO:0000243", "uniprot": "Q7KX00"}, "name": "Y48G8AL.15", "id": "WBGene00021692"}, {"annotation": {"kegg.genes": "CELE_ZK795.1", "wormbase": "WBGene00014081", "sbo": "SBO:0000243", "uniprot": "O62519"}, "name": "impk-1", "id": "WBGene00014081"}, {"annotation": {"kegg.genes": "CELE_F48F5.5", "wormbase": "WBGene00001406", "sbo": "SBO:0000243", "uniprot": "G5EEP3"}, "name": "fce-2", "id": "WBGene00001406"}, {"annotation": {"kegg.genes": "CELE_Y56A3A.36", "wormbase": "WBGene00044233", "sbo": "SBO:0000243", "uniprot": "Q56VX7"}, "name": "Y56A3A.36", "id": "WBGene00044233"}, {"annotation": {"kegg.genes": "CELE_Y37D8A.23", "wormbase": "WBGene00006762", "sbo": "SBO:0000243", "uniprot": ["G5EDB7", "Q8I4E0", "Q8I4D9"]}, "name": "unc-25", "id": "WBGene00006762"}, {"annotation": {"kegg.genes": "CELE_F02H6.5", "wormbase": "WBGene00008538", "sbo": "SBO:0000243", "uniprot": ["C6KRP6", "C6KRP5", "O62133"]}, "name": "sqrd-1", "id": "WBGene00008538"}, {"annotation": {"kegg.genes": "CELE_F25B4.1", "wormbase": "WBGene00017765", "sbo": "SBO:0000243", "uniprot": "Q22968"}, "name": "gcst-1", "id": "WBGene00017765"}, {"annotation": {"kegg.genes": "CELE_ZK809.3", "wormbase": "WBGene00014086", "sbo": "SBO:0000243", "uniprot": "Q23597"}, "name": "ZK809.3", "id": "WBGene00014086"}, {"annotation": {"kegg.genes": "CELE_R53.1", "wormbase": "WBGene00011271", "sbo": "SBO:0000243", "uniprot": ["Q22017", "I2HAD4", "I2HAD5"]}, "name": "flad-1", "id": "WBGene00011271"}, {"annotation": {"kegg.genes": "CELE_F26H9.4", "wormbase": "WBGene00009176", "sbo": "SBO:0000243", "uniprot": "P91851"}, "name": "nmat-2", "id": "WBGene00009176"}, {"annotation": {"kegg.genes": "CELE_Y105E8A.4", "wormbase": "WBGene00001156", "sbo": "SBO:0000243", "uniprot": "Q9NEZ8"}, "name": "ech-7", "id": "WBGene00001156"}, {"annotation": {"kegg.genes": "CELE_F42F12.3", "wormbase": "WBGene00009635", "sbo": "SBO:0000243", "uniprot": "Q20344"}, "name": "F42F12.3", "id": "WBGene00009635"}, {"annotation": {"kegg.genes": "CELE_W10C8.5", "wormbase": "WBGene00021128", "sbo": "SBO:0000243", "uniprot": "O45011"}, "name": "W10C8.5", "id": "WBGene00021128"}, {"annotation": {"kegg.genes": "CELE_F48E8.3", "wormbase": "WBGene00018610", "sbo": "SBO:0000243", "uniprot": "Q09567"}, "name": "F48E8.3", "id": "WBGene00018610"}, {"annotation": {"kegg.genes": "ND4L", "wormbase": "WBGene00010958", "sbo": "SBO:0000243", "uniprot": ["G5EGJ8", "P24886"]}, "name": "ndfl-4", "id": "WBGene00010958"}, {"annotation": {"kegg.genes": "CELE_F08F8.7", "wormbase": "WBGene00017272", "sbo": "SBO:0000243", "uniprot": "Q95ZW2"}, "name": "F08F8.7", "id": "WBGene00017272"}, {"annotation": {"kegg.genes": "CELE_C06E7.1", "wormbase": "WBGene00015538", "sbo": "SBO:0000243", "uniprot": "P50305"}, "name": "sams-3", "id": "WBGene00015538"}, {"annotation": {"kegg.genes": "CELE_F54F3.4", "wormbase": "WBGene00010063", "sbo": "SBO:0000243", "uniprot": "G5EGA6"}, "name": "dhrs-4", "id": "WBGene00010063"}, {"annotation": {"kegg.genes": "CELE_R07E4.4", "wormbase": "WBGene00003254", "sbo": "SBO:0000243", "uniprot": "Q21815"}, "name": "mig-23", "id": "WBGene00003254"}, {"annotation": {"kegg.genes": "CELE_Y73E7A.7", "wormbase": "WBGene00000269", "sbo": "SBO:0000243", "uniprot": "Q9GUM2"}, "name": "bre-4", "id": "WBGene00000269"}, {"annotation": {"kegg.genes": "CELE_Y71H2AM.16", "wormbase": "WBGene00022181", "sbo": "SBO:0000243", "uniprot": "Q9BL40"}, "name": "pho-9", "id": "WBGene00022181"}, {"annotation": {"kegg.genes": "CELE_R13H4.3", "wormbase": "WBGene00011262", "sbo": "SBO:0000243", "uniprot": "P90949"}, "name": "pho-8", "id": "WBGene00011262"}, {"annotation": {"kegg.genes": "CELE_F33A8.5", "wormbase": "WBGene00009353", "sbo": "SBO:0000243", "uniprot": "O62215"}, "name": "sdhd-1", "id": "WBGene00009353"}, {"annotation": {"kegg.genes": "CELE_B0361.7", "wormbase": "WBGene00015161", "sbo": "SBO:0000243", "uniprot": "Q10944"}, "name": "pho-5", "id": "WBGene00015161"}, {"annotation": {"kegg.genes": "CELE_T16D1.2", "wormbase": "WBGene00004023", "sbo": "SBO:0000243", "uniprot": "Q22525"}, "name": "pho-4", "id": "WBGene00004023"}, {"annotation": {"kegg.genes": "CELE_Y10G11A.1", "wormbase": "WBGene00012423", "sbo": "SBO:0000243", "uniprot": ["E4MYG2", "Q95ZJ9"]}, "name": "Y10G11A.1", "id": "WBGene00012423"}, {"annotation": {"kegg.genes": "CELE_F52E1.8", "wormbase": "WBGene00018696", "sbo": "SBO:0000243", "uniprot": "Q20662"}, "name": "pho-6", "id": "WBGene00018696"}, {"annotation": {"kegg.genes": "CELE_EGAP2.3", "wormbase": "WBGene00004020", "sbo": "SBO:0000243", "uniprot": "Q19076"}, "name": "pho-1", "id": "WBGene00004020"}, {"annotation": {"kegg.genes": "CELE_T21B6.2", "wormbase": "WBGene00011879", "sbo": "SBO:0000243", "uniprot": "Q22630"}, "name": "pho-7", "id": "WBGene00011879"}, {"annotation": {"kegg.genes": "CELE_C04C3.3", "wormbase": "WBGene00015413", "sbo": "SBO:0000243", "uniprot": "O44451"}, "name": "pdhb-1", "id": "WBGene00015413"}, {"annotation": {"kegg.genes": "CELE_F09F7.4", "wormbase": "WBGene00017301", "sbo": "SBO:0000243", "uniprot": ["Q19278", "Q8MNT7"]}, "name": "hach-1", "id": "WBGene00017301"}, {"annotation": {"kegg.genes": "CELE_M02B7.4", "wormbase": "WBGene00019725", "sbo": "SBO:0000243"}, "name": "algn-14", "id": "WBGene00019725"}, {"annotation": {"kegg.genes": "CELE_F49E8.4", "wormbase": "WBGene00000392", "sbo": "SBO:0000243", "uniprot": "Q20628"}, "name": "cdd-2", "id": "WBGene00000392"}, {"annotation": {"kegg.genes": "CELE_B0361.8", "wormbase": "WBGene00015162", "sbo": "SBO:0000243", "uniprot": "P53993"}, "name": "algn-11", "id": "WBGene00015162"}, {"annotation": {"kegg.genes": "CELE_F57B9.1", "wormbase": "WBGene00018996", "sbo": "SBO:0000243", "uniprot": "Q20939"}, "name": "F57B9.1", "id": "WBGene00018996"}, {"annotation": {"kegg.genes": "CELE_R10D12.12", "wormbase": "WBGene00011193", "sbo": "SBO:0000243", "uniprot": "P92012"}, "name": "algn-13", "id": "WBGene00011193"}, {"annotation": {"kegg.genes": "CELE_F26F4.11", "wormbase": "WBGene00017830", "sbo": "SBO:0000243", "uniprot": "Q19826"}, "name": "rpb-8", "id": "WBGene00017830"}, {"annotation": {"kegg.genes": "CELE_ZK1127.2", "wormbase": "WBGene00022849", "sbo": "SBO:0000243", "uniprot": "Q23404"}, "name": "acs-6", "id": "WBGene00022849"}, {"annotation": {"kegg.genes": "CELE_C54E4.3", "wormbase": "WBGene00001557", "sbo": "SBO:0000243", "uniprot": "Q6DNF3"}, "name": "gcy-37", "id": "WBGene00001557"}, {"annotation": {"kegg.genes": "CELE_F47B10.2", "wormbase": "WBGene00009813", "sbo": "SBO:0000243", "uniprot": "Q20502"}, "name": "haly-1", "id": "WBGene00009813"}, {"annotation": {"kegg.genes": "CELE_T03F1.8", "wormbase": "WBGene00020190", "sbo": "SBO:0000243", "uniprot": ["A5HU98", "P91425"]}, "name": "guk-1", "id": "WBGene00020190"}, {"annotation": {"kegg.genes": "CELE_F33D4.4", "wormbase": "WBGene00017996", "sbo": "SBO:0000243", "uniprot": "O44186"}, "name": "F33D4.4", "id": "WBGene00017996"}, {"annotation": {"kegg.genes": "CELE_F43G6.5", "wormbase": "WBGene00009658", "sbo": "SBO:0000243", "uniprot": "G5EBX5"}, "name": "F43G6.5", "id": "WBGene00009658"}, {"annotation": {"kegg.genes": "CELE_K07A3.1", "wormbase": "WBGene00001404", "sbo": "SBO:0000243", "uniprot": "G5EBJ7"}, "name": "fbp-1", "id": "WBGene00001404"}, {"annotation": {"kegg.genes": "CELE_F35G12.1", "wormbase": "WBGene00009439", "sbo": "SBO:0000243", "uniprot": "Q20048"}, "name": "mlcd-1", "id": "WBGene00009439"}, {"annotation": {"kegg.genes": "CELE_M153.1", "wormbase": "WBGene00010924", "sbo": "SBO:0000243", "uniprot": "Q21544"}, "name": "M153.1", "id": "WBGene00010924"}, {"annotation": {"kegg.genes": "CELE_ZK836.2", "wormbase": "WBGene00014098", "sbo": "SBO:0000243", "uniprot": ["F5GUD7", "Q23629"]}, "name": "ogdh-2", "id": "WBGene00014098"}, {"annotation": {"kegg.genes": "CELE_K11H3.3", "wormbase": "WBGene00010780", "sbo": "SBO:0000243", "uniprot": "P34519"}, "name": "K11H3.3", "id": "WBGene00010780"}, {"annotation": {"kegg.genes": "CELE_H13N06.4", "wormbase": "WBGene00010397", "sbo": "SBO:0000243", "uniprot": ["Q9XTQ8", "Q564P9"]}, "name": "suox-1", "id": "WBGene00010397"}, {"annotation": {"kegg.genes": "CELE_Y69F12A.2", "wormbase": "WBGene00000118", "sbo": "SBO:0000243", "uniprot": ["Q7Z1Q2", "Q7Z1Q3"]}, "name": "alh-12", "id": "WBGene00000118"}, {"annotation": {"kegg.genes": "CELE_T04D3.3", "wormbase": "WBGene00011433", "sbo": "SBO:0000243", "uniprot": ["O18696", "B5BM35"]}, "name": "pde-1", "id": "WBGene00011433"}, {"annotation": {"kegg.genes": "CELE_C08H9.3", "wormbase": "WBGene00007464", "sbo": "SBO:0000243", "uniprot": "P52887"}, "name": "C08H9.3", "id": "WBGene00007464"}, {"annotation": {"kegg.genes": "CELE_W06D4.1", "wormbase": "WBGene00001843", "sbo": "SBO:0000243", "uniprot": "Q9Y041"}, "name": "hgo-1", "id": "WBGene00001843"}, {"annotation": {"kegg.genes": "CELE_Y17G7B.7", "wormbase": "WBGene00006601", "sbo": "SBO:0000243", "uniprot": "Q10657"}, "name": "tpi-1", "id": "WBGene00006601"}, {"annotation": {"kegg.genes": "CELE_Y53G8B.1", "wormbase": "WBGene00021817", "sbo": "SBO:0000243", "uniprot": "Q9N4S0"}, "name": "Y53G8B.1", "id": "WBGene00021817"}, {"annotation": {"kegg.genes": "CELE_Y53G8B.2", "wormbase": "WBGene00021818", "sbo": "SBO:0000243", "uniprot": "Q9N4S3"}, "name": "Y53G8B.2", "id": "WBGene00021818"}, {"annotation": {"kegg.genes": "CELE_F52C9.3", "wormbase": "WBGene00018674", "sbo": "SBO:0000243", "uniprot": "Q10123"}, "name": "F52C9.3", "id": "WBGene00018674"}, {"annotation": {"kegg.genes": "CELE_F55H2.2", "wormbase": "WBGene00010130", "sbo": "SBO:0000243", "uniprot": "P34462"}, "name": "vha-14", "id": "WBGene00010130"}, {"annotation": {"kegg.genes": "CELE_Y7A9A.1", "wormbase": "WBGene00012416", "sbo": "SBO:0000243", "uniprot": "O18256"}, "name": "Y7A9A.1", "id": "WBGene00012416"}, {"annotation": {"kegg.genes": "CELE_Y38F2AR.12", "wormbase": "WBGene00021430", "sbo": "SBO:0000243", "uniprot": "Q86FM9"}, "name": "Y38F2AR.12", "id": "WBGene00021430"}, {"annotation": {"kegg.genes": "CELE_C15H9.1", "wormbase": "WBGene00003778", "sbo": "SBO:0000243", "uniprot": "Q18031"}, "name": "nnt-1", "id": "WBGene00003778"}, {"annotation": {"kegg.genes": "CELE_C52B9.7", "wormbase": "WBGene00003907", "sbo": "SBO:0000243", "uniprot": "Q22943"}, "name": "paf-2", "id": "WBGene00003907"}, {"annotation": {"kegg.genes": "CELE_W03G9.6", "wormbase": "WBGene00003906", "sbo": "SBO:0000243", "uniprot": "G5EGT1"}, "name": "paf-1", "id": "WBGene00003906"}, {"annotation": {"kegg.genes": "CELE_C25F6.3", "wormbase": "WBGene00016103", "sbo": "SBO:0000243", "uniprot": "Q18164"}, "name": "dpyd-1", "id": "WBGene00016103"}, {"annotation": {"kegg.genes": "CELE_E04F6.3", "wormbase": "WBGene00017123", "sbo": "SBO:0000243", "uniprot": "Q19058"}, "name": "maoc-1", "id": "WBGene00017123"}, {"annotation": {"kegg.genes": "CELE_F55A3.5", "wormbase": "WBGene00018850", "sbo": "SBO:0000243", "uniprot": "Q9N5S2"}, "name": "gpx-8", "id": "WBGene00018850"}, {"annotation": {"kegg.genes": "CELE_F42G8.10", "wormbase": "WBGene00018361", "sbo": "SBO:0000243", "uniprot": "O44509"}, "name": "F42G8.10", "id": "WBGene00018361"}, {"annotation": {"kegg.genes": "CELE_T06C12.10", "wormbase": "WBGene00011517", "sbo": "SBO:0000243", "uniprot": "O18037"}, "name": "cgt-1", "id": "WBGene00011517"}, {"annotation": {"kegg.genes": "CELE_C11E4.1", "wormbase": "WBGene00007516", "sbo": "SBO:0000243", "uniprot": "Q93204"}, "name": "gpx-5", "id": "WBGene00007516"}, {"annotation": {"kegg.genes": "CELE_Y94H6A.4", "wormbase": "WBGene00022377", "sbo": "SBO:0000243", "uniprot": "Q9N2X2"}, "name": "gpx-4", "id": "WBGene00022377"}, {"annotation": {"kegg.genes": "CELE_R03G5.5", "wormbase": "WBGene00019846", "sbo": "SBO:0000243", "uniprot": ["A8WFK7", "A8WFK6"]}, "name": "gpx-7", "id": "WBGene00019846"}, {"annotation": {"kegg.genes": "CELE_F56F10.3", "wormbase": "WBGene00018986", "sbo": "SBO:0000243", "uniprot": "Q20893"}, "name": "cdo-1", "id": "WBGene00018986"}, {"annotation": {"kegg.genes": "CELE_F26E4.12", "wormbase": "WBGene00009165", "sbo": "SBO:0000243", "uniprot": "O02621"}, "name": "gpx-1", "id": "WBGene00009165"}, {"annotation": {"kegg.genes": "CELE_F20B4.6", "wormbase": "WBGene00017625", "sbo": "SBO:0000243", "uniprot": "G5EC84"}, "name": "cgt-2", "id": "WBGene00017625"}, {"annotation": {"kegg.genes": "CELE_C11E4.2", "wormbase": "WBGene00007517", "sbo": "SBO:0000243", "uniprot": "Q95003"}, "name": "gpx-3", "id": "WBGene00007517"}, {"annotation": {"kegg.genes": "CELE_R05H10.5", "wormbase": "WBGene00011045", "sbo": "SBO:0000243", "uniprot": "O62327"}, "name": "gpx-2", "id": "WBGene00011045"}, {"annotation": {"kegg.genes": "CELE_R07B7.5", "wormbase": "WBGene00011089", "sbo": "SBO:0000243", "uniprot": "Q21795"}, "name": "kmo-1", "id": "WBGene00011089"}, {"annotation": {"kegg.genes": "CELE_ZK792.1", "wormbase": "WBGene00014076", "sbo": "SBO:0000243", "uniprot": "Q95PW2"}, "name": "ZK792.1", "id": "WBGene00014076"}, {"annotation": {"kegg.genes": "CELE_Y65B4BL.5", "wormbase": "WBGene00022037", "sbo": "SBO:0000243", "uniprot": "Q9N302"}, "name": "acs-13", "id": "WBGene00022037"}, {"annotation": {"kegg.genes": "CELE_R07B7.4", "wormbase": "WBGene00011088", "sbo": "SBO:0000243", "uniprot": ["B5BM30", "Q21794"]}, "name": "kmo-2", "id": "WBGene00011088"}, {"annotation": {"kegg.genes": "CELE_R07C3.4", "wormbase": "WBGene00019920", "sbo": "SBO:0000243", "uniprot": "O16775"}, "name": "acs-15", "id": "WBGene00019920"}, {"annotation": {"kegg.genes": "CELE_F11A3.1", "wormbase": "WBGene00008669", "sbo": "SBO:0000243", "uniprot": "Q19339"}, "name": "acs-14", "id": "WBGene00008669"}, {"annotation": {"kegg.genes": "CELE_C46F4.2", "wormbase": "WBGene00016716", "sbo": "SBO:0000243", "uniprot": "Q18660"}, "name": "acs-17", "id": "WBGene00016716"}, {"annotation": {"kegg.genes": "CELE_F31F4.7", "wormbase": "WBGene00017959", "sbo": "SBO:0000243", "uniprot": "O17123"}, "name": "ugt-42", "id": "WBGene00017959"}, {"annotation": {"kegg.genes": "CELE_C36A4.9", "wormbase": "WBGene00007969", "sbo": "SBO:0000243", "uniprot": ["Q18496", "Q65ZB8"]}, "name": "acs-19", "id": "WBGene00007969"}, {"annotation": {"kegg.genes": "CELE_R09E10.3", "wormbase": "WBGene00011173", "sbo": "SBO:0000243", "uniprot": "Q21872"}, "name": "acs-18", "id": "WBGene00011173"}, {"annotation": {"kegg.genes": "CELE_F58H1.3", "wormbase": "WBGene00010286", "sbo": "SBO:0000243", "uniprot": "Q21012"}, "name": "F58H1.3", "id": "WBGene00010286"}, {"annotation": {"kegg.genes": "CELE_F10D2.11", "wormbase": "WBGene00017336", "sbo": "SBO:0000243", "uniprot": "O16922"}, "name": "ugt-41", "id": "WBGene00017336"}, {"annotation": {"kegg.genes": "CELE_F59A7.7", "wormbase": "WBGene00019094", "sbo": "SBO:0000243", "uniprot": "O16282"}, "name": "F59A7.7", "id": "WBGene00019094"}, {"annotation": {"kegg.genes": "CELE_F10D2.5", "wormbase": "WBGene00017331", "sbo": "SBO:0000243", "uniprot": "O16914"}, "name": "ugt-40", "id": "WBGene00017331"}, {"annotation": {"kegg.genes": "CELE_C16A3.10", "wormbase": "WBGene00015814", "sbo": "SBO:0000243", "uniprot": ["Q18040", "Q8MNV6", "Q5TYL8"]}, "name": "oatr-1", "id": "WBGene00015814"}, {"annotation": {"kegg.genes": "CELE_Y62E10A.13", "wormbase": "WBGene00013379", "sbo": "SBO:0000243", "uniprot": ["Q9U1W7", "Q95Q10", "D3NQB6", "Q9U1W6"]}, "name": "Y62E10A.13", "id": "WBGene00013379"}, {"annotation": {"kegg.genes": "CELE_C08B11.8", "wormbase": "WBGene00007435", "sbo": "SBO:0000243", "uniprot": "Q09226"}, "name": "C08B11.8", "id": "WBGene00007435"}, {"annotation": {"kegg.genes": "CELE_K12H4.7", "wormbase": "WBGene00019682", "sbo": "SBO:0000243", "uniprot": "P34528"}, "name": "K12H4.7", "id": "WBGene00019682"}, {"annotation": {"kegg.genes": "CELE_C34E10.4", "wormbase": "WBGene00006946", "sbo": "SBO:0000243", "uniprot": "P46579"}, "name": "prx-10", "id": "WBGene00006946"}, {"annotation": {"kegg.genes": "CELE_C34B2.7", "wormbase": "WBGene00016392", "sbo": "SBO:0000243", "uniprot": "O44954"}, "name": "sdha-2", "id": "WBGene00016392"}, {"annotation": {"kegg.genes": "CELE_K01C8.3", "wormbase": "WBGene00006562", "sbo": "SBO:0000243", "uniprot": ["Q95ZS2", "Q21087"]}, "name": "tdc-1", "id": "WBGene00006562"}, {"annotation": {"kegg.genes": "CELE_Y80D3A.1", "wormbase": "WBGene00006945", "sbo": "SBO:0000243", "uniprot": "G5EDY2"}, "name": "wars-1", "id": "WBGene00006945"}, {"annotation": {"kegg.genes": "CELE_C03A7.13", "wormbase": "WBGene00015371", "sbo": "SBO:0000243", "uniprot": "O16510"}, "name": "C03A7.13", "id": "WBGene00015371"}, {"annotation": {"kegg.genes": "CELE_ZK622.3", "wormbase": "WBGene00022781", "sbo": "SBO:0000243", "uniprot": ["H2KZF5", "Q23552", "Q8IFX3", "Q86NB3"]}, "name": "pmt-1", "id": "WBGene00022781"}, {"annotation": {"kegg.genes": "CELE_F54D11.1", "wormbase": "WBGene00018811", "sbo": "SBO:0000243", "uniprot": "Q22993"}, "name": "pmt-2", "id": "WBGene00018811"}, {"annotation": {"kegg.genes": "CELE_F52A8.5", "wormbase": "WBGene00009918", "sbo": "SBO:0000243", "uniprot": "Q20634"}, "name": "gcsh-2", "id": "WBGene00009918"}, {"annotation": {"kegg.genes": "CELE_VF13D12L.1", "wormbase": "WBGene00012148", "sbo": "SBO:0000243", "uniprot": "G5ED01"}, "name": "inos-1", "id": "WBGene00012148"}, {"annotation": {"kegg.genes": "CELE_D1025.2", "wormbase": "WBGene00008354", "sbo": "SBO:0000243", "uniprot": "O62122"}, "name": "gcsh-1", "id": "WBGene00008354"}, {"annotation": {"kegg.genes": "CELE_Y75B8A.24", "wormbase": "WBGene00013557", "sbo": "SBO:0000243", "uniprot": "Q9XW63"}, "name": "Y75B8A.24", "id": "WBGene00013557"}, {"annotation": {"kegg.genes": "CELE_F54A3.4", "wormbase": "WBGene00018783", "sbo": "SBO:0000243", "uniprot": "Q9N4K2"}, "name": "cbs-2", "id": "WBGene00018783"}, {"annotation": {"kegg.genes": "CELE_R06C1.2", "wormbase": "WBGene00011058", "sbo": "SBO:0000243", "uniprot": "O62336"}, "name": "fdps-1", "id": "WBGene00011058"}, {"annotation": {"kegg.genes": "CELE_F08A8.1", "wormbase": "WBGene00008564", "sbo": "SBO:0000243", "uniprot": ["Q2L6T9", "O62140", "Q7JK62"]}, "name": "acox-1.1", "id": "WBGene00008564"}, {"annotation": {"kegg.genes": "CELE_K07E3.3", "wormbase": "WBGene00000929", "sbo": "SBO:0000243", "uniprot": "Q21285"}, "name": "dao-3", "id": "WBGene00000929"}, {"annotation": {"kegg.genes": "CELE_F08A8.3", "wormbase": "WBGene00008566", "sbo": "SBO:0000243", "uniprot": "O62138"}, "name": "acox-1.3", "id": "WBGene00008566"}, {"annotation": {"kegg.genes": "CELE_F08A8.2", "wormbase": "WBGene00008565", "sbo": "SBO:0000243", "uniprot": "O62137"}, "name": "acox-1.2", "id": "WBGene00008565"}, {"annotation": {"kegg.genes": "CELE_C48B4.1", "wormbase": "WBGene00008167", "sbo": "SBO:0000243", "uniprot": "P34355"}, "name": "acox-1.5", "id": "WBGene00008167"}, {"annotation": {"kegg.genes": "CELE_F08A8.4", "wormbase": "WBGene00008567", "sbo": "SBO:0000243", "uniprot": "O62139"}, "name": "acox-1.4", "id": "WBGene00008567"}, {"annotation": {"kegg.genes": "CELE_T19B10.3", "wormbase": "WBGene00011832", "sbo": "SBO:0000243", "uniprot": "Q27526"}, "name": "bgal-1", "id": "WBGene00011832"}, {"annotation": {"kegg.genes": "CELE_F59F4.1", "wormbase": "WBGene00010336", "sbo": "SBO:0000243", "uniprot": "Q93839"}, "name": "acox-1.6", "id": "WBGene00010336"}, {"annotation": {"kegg.genes": "CELE_F42D1.2", "wormbase": "WBGene00009628", "sbo": "SBO:0000243", "uniprot": "Q93703"}, "name": "tatn-1", "id": "WBGene00009628"}, {"annotation": {"kegg.genes": "CELE_M57.2", "wormbase": "WBGene00019778", "sbo": "SBO:0000243", "uniprot": "Q9TYY0"}, "name": "M57.2", "id": "WBGene00019778"}, {"annotation": {"kegg.genes": "CELE_B0395.3", "wormbase": "WBGene00007175", "sbo": "SBO:0000243", "uniprot": "Q17499"}, "name": "B0395.3", "id": "WBGene00007175"}, {"annotation": {"kegg.genes": "CELE_C53A3.2", "wormbase": "WBGene00016892", "sbo": "SBO:0000243", "uniprot": "O44538"}, "name": "C53A3.2", "id": "WBGene00016892"}, {"annotation": {"kegg.genes": "CELE_C43F9.6", "wormbase": "WBGene00008074", "sbo": "SBO:0000243", "uniprot": "Q9XUG9"}, "name": "nkb-2", "id": "WBGene00008074"}, {"annotation": {"kegg.genes": "CELE_C17E4.9", "wormbase": "WBGene00007646", "sbo": "SBO:0000243", "uniprot": "Q93235"}, "name": "nkb-1", "id": "WBGene00007646"}, {"annotation": {"kegg.genes": "CELE_F25G6.6", "wormbase": "WBGene00003816", "sbo": "SBO:0000243", "uniprot": "O16924"}, "name": "asns-1", "id": "WBGene00003816"}, {"annotation": {"kegg.genes": "CELE_Y54F10AM.5", "wormbase": "WBGene00021849", "sbo": "SBO:0000243", "uniprot": "Q9BL03"}, "name": "Y54F10AM.5", "id": "WBGene00021849"}, {"annotation": {"kegg.genes": "CELE_F53F4.10", "wormbase": "WBGene00009992", "sbo": "SBO:0000243", "uniprot": "Q20719"}, "name": "F53F4.10", "id": "WBGene00009992"}, {"annotation": {"kegg.genes": "CELE_Y44A6D.5", "wormbase": "WBGene00012855", "sbo": "SBO:0000243", "uniprot": "Q9XXD8"}, "name": "Y44A6D.5", "id": "WBGene00012855"}, {"annotation": {"kegg.genes": "CELE_Y57A10A.15", "wormbase": "WBGene00013258", "sbo": "SBO:0000243", "uniprot": "Q9U208"}, "name": "polg-1", "id": "WBGene00013258"}, {"annotation": {"kegg.genes": "CELE_F49E8.5", "wormbase": "WBGene00000996", "sbo": "SBO:0000243", "uniprot": "Q27257"}, "name": "dif-1", "id": "WBGene00000996"}, {"annotation": {"kegg.genes": "CELE_T27A3.6", "wormbase": "WBGene00020842", "sbo": "SBO:0000243", "uniprot": "P91500"}, "name": "T27A3.6", "id": "WBGene00020842"}, {"annotation": {"kegg.genes": "CELE_H04M03.1", "wormbase": "WBGene00019151", "sbo": "SBO:0000243", "uniprot": "Q9TYQ8"}, "name": "pck-3", "id": "WBGene00019151"}, {"annotation": {"kegg.genes": "CELE_F32G8.6", "wormbase": "WBGene00000298", "sbo": "SBO:0000243", "uniprot": "Q19980"}, "name": "cat-4", "id": "WBGene00000298"}, {"annotation": {"kegg.genes": "CELE_T07C12.9", "wormbase": "WBGene00011573", "sbo": "SBO:0000243", "uniprot": "Q22279"}, "name": "anmt-3", "id": "WBGene00011573"}, {"annotation": {"kegg.genes": "CELE_B0303.2", "wormbase": "WBGene00015124", "sbo": "SBO:0000243", "uniprot": "P34254"}, "name": "anmt-1", "id": "WBGene00015124"}, {"annotation": {"kegg.genes": "CELE_W01C8.6", "wormbase": "WBGene00000295", "sbo": "SBO:0000243", "uniprot": ["Q9GNP0", "Q7Z1Q0"]}, "name": "cat-1", "id": "WBGene00000295"}, {"annotation": {"kegg.genes": "CELE_B0222.4", "wormbase": "WBGene00006418", "sbo": "SBO:0000243", "uniprot": "Q17456"}, "name": "tag-38", "id": "WBGene00006418"}, {"annotation": {"kegg.genes": "CELE_C07D8.6", "wormbase": "WBGene00015565", "sbo": "SBO:0000243", "uniprot": "P91020"}, "name": "C07D8.6", "id": "WBGene00015565"}, {"annotation": {"kegg.genes": "CELE_F23H11.9", "wormbase": "WBGene00017763", "sbo": "SBO:0000243", "uniprot": "O01916"}, "name": "crls-1", "id": "WBGene00017763"}, {"annotation": {"kegg.genes": "CELE_K03D10.3", "wormbase": "WBGene00010537", "sbo": "SBO:0000243", "uniprot": "Q9U3C3"}, "name": "mys-2", "id": "WBGene00010537"}, {"annotation": {"kegg.genes": "CELE_VC5.4", "wormbase": "WBGene00007029", "sbo": "SBO:0000243", "uniprot": "Q9TYU5"}, "name": "mys-1", "id": "WBGene00007029"}, {"annotation": {"kegg.genes": "CELE_C24F3.4", "wormbase": "WBGene00007698", "sbo": "SBO:0000243", "uniprot": ["F3Y5P7", "F3Y5P6", "Q9XXK6"]}, "name": "qns-1", "id": "WBGene00007698"}, {"annotation": {"kegg.genes": "CELE_T05H4.13", "wormbase": "WBGene00000110", "sbo": "SBO:0000243", "uniprot": ["Q8MXJ7", "Q86S57", "O16518"]}, "name": "alh-4", "id": "WBGene00000110"}, {"annotation": {"kegg.genes": "CELE_F07A11.5", "wormbase": "WBGene00008548", "sbo": "SBO:0000243", "uniprot": "Q19133"}, "name": "F07A11.5", "id": "WBGene00008548"}, {"annotation": {"kegg.genes": "CELE_F44E7.2", "wormbase": "WBGene00018424", "sbo": "SBO:0000243", "uniprot": "O16247"}, "name": "F44E7.2", "id": "WBGene00018424"}, {"annotation": {"kegg.genes": "CELE_C04G6.3", "wormbase": "WBGene00004040", "sbo": "SBO:0000243", "uniprot": "G5EDU3"}, "name": "pld-1", "id": "WBGene00004040"}, {"annotation": {"kegg.genes": "CELE_T15B7.2", "wormbase": "WBGene00020517", "sbo": "SBO:0000243", "uniprot": "O17040"}, "name": "hpo-8", "id": "WBGene00020517"}, {"annotation": {"kegg.genes": "CELE_F31D4.9", "wormbase": "WBGene00009294", "sbo": "SBO:0000243", "uniprot": "Q9U3H4"}, "name": "F31D4.9", "id": "WBGene00009294"}, {"annotation": {"kegg.genes": "CELE_T26A5.7", "wormbase": "WBGene00004781", "sbo": "SBO:0000243", "uniprot": ["Q22795", "G8JY06"]}, "name": "set-1", "id": "WBGene00004781"}, {"annotation": {"kegg.genes": "CELE_Y87G2A.8", "wormbase": "WBGene00013597", "sbo": "SBO:0000243", "uniprot": ["Q7K707", "Q9U1Q2"]}, "name": "gpi-1", "id": "WBGene00013597"}, {"annotation": {"kegg.genes": "CELE_Y43F8B.4", "wormbase": "WBGene00012815", "sbo": "SBO:0000243", "uniprot": ["B1V8J4", "B1V8J3"]}, "name": "phy-4", "id": "WBGene00012815"}, {"annotation": {"kegg.genes": "CELE_T20B3.7", "wormbase": "WBGene00004026", "sbo": "SBO:0000243", "uniprot": "Q9XUP0"}, "name": "phy-3", "id": "WBGene00004026"}, {"annotation": {"kegg.genes": "CELE_F35G2.4", "wormbase": "WBGene00004025", "sbo": "SBO:0000243", "uniprot": "Q20065"}, "name": "phy-2", "id": "WBGene00004025"}, {"annotation": {"kegg.genes": "CELE_F13H10.5", "wormbase": "WBGene00008776", "sbo": "SBO:0000243", "uniprot": "O45359"}, "name": "F13H10.5", "id": "WBGene00008776"}, {"annotation": {"kegg.genes": "CELE_F35C8.5", "wormbase": "WBGene00018036", "sbo": "SBO:0000243", "uniprot": "Q20027"}, "name": "F35C8.5", "id": "WBGene00018036"}, {"annotation": {"kegg.genes": "CELE_T09F3.3", "wormbase": "WBGene00001683", "sbo": "SBO:0000243", "uniprot": "P04970"}, "name": "gpd-1", "id": "WBGene00001683"}, {"annotation": {"kegg.genes": "CELE_K08B4.3", "wormbase": "WBGene00019515", "sbo": "SBO:0000243", "uniprot": "Q9TYY5"}, "name": "ugt-19", "id": "WBGene00019515"}, {"annotation": {"kegg.genes": "CELE_K10B3.7", "wormbase": "WBGene00001685", "sbo": "SBO:0000243", "uniprot": "P17330"}, "name": "gpd-3", "id": "WBGene00001685"}, {"annotation": {"kegg.genes": "CELE_K10B3.8", "wormbase": "WBGene00001684", "sbo": "SBO:0000243", "uniprot": "P17329"}, "name": "gpd-2", "id": "WBGene00001684"}, {"annotation": {"kegg.genes": "CELE_Y38F2AL.3", "wormbase": "WBGene00006920", "sbo": "SBO:0000243", "uniprot": "Q9XXU9"}, "name": "vha-11", "id": "WBGene00006920"}, {"annotation": {"kegg.genes": "CELE_F33H1.2", "wormbase": "WBGene00001686", "sbo": "SBO:0000243", "uniprot": "P17331"}, "name": "gpd-4", "id": "WBGene00001686"}, {"annotation": {"kegg.genes": "CELE_Y49A3A.2", "wormbase": "WBGene00013025", "sbo": "SBO:0000243", "uniprot": "Q9XW92"}, "name": "vha-13", "id": "WBGene00013025"}, {"annotation": {"kegg.genes": "CELE_K09A9.6", "wormbase": "WBGene00010703", "sbo": "SBO:0000243", "uniprot": ["A8WHT8", "A8WHT9", "G5EEF4"]}, "name": "K09A9.6", "id": "WBGene00010703"}, {"annotation": {"kegg.genes": "CELE_T19H12.11", "wormbase": "WBGene00020594", "sbo": "SBO:0000243", "uniprot": "Q3S1L2"}, "name": "ugt-10", "id": "WBGene00020594"}, {"annotation": {"kegg.genes": "CELE_T19H12.10", "wormbase": "WBGene00020593", "sbo": "SBO:0000243", "uniprot": "O01616"}, "name": "ugt-11", "id": "WBGene00020593"}, {"annotation": {"kegg.genes": "CELE_T19H12.9", "wormbase": "WBGene00020592", "sbo": "SBO:0000243", "uniprot": "O01614"}, "name": "ugt-12", "id": "WBGene00020592"}, {"annotation": {"kegg.genes": "CELE_H23N18.1", "wormbase": "WBGene00019232", "sbo": "SBO:0000243", "uniprot": "Q9TXZ6"}, "name": "ugt-13", "id": "WBGene00019232"}, {"annotation": {"kegg.genes": "CELE_Y55H10A.1", "wormbase": "WBGene00021952", "sbo": "SBO:0000243", "uniprot": "Q9TYW1"}, "name": "vha-19", "id": "WBGene00021952"}, {"annotation": {"kegg.genes": "CELE_C37H5.6", "wormbase": "WBGene00016509", "sbo": "SBO:0000243", "uniprot": "P91134"}, "name": "adss-1", "id": "WBGene00016509"}, {"annotation": {"kegg.genes": "CELE_ZC443.6", "wormbase": "WBGene00013901", "sbo": "SBO:0000243", "uniprot": "G5EGK7"}, "name": "ugt-16", "id": "WBGene00013901"}, {"annotation": {"kegg.genes": "CELE_C08B6.1", "wormbase": "WBGene00007422", "sbo": "SBO:0000243", "uniprot": ["Q17813", "A5JYT6"]}, "name": "ugt-17", "id": "WBGene00007422"}, {"annotation": {"kegg.genes": "CELE_D1022.8", "wormbase": "WBGene00000280", "sbo": "SBO:0000243", "uniprot": "Q18932"}, "name": "cah-2", "id": "WBGene00000280"}, {"annotation": {"kegg.genes": "CELE_K05G3.3", "wormbase": "WBGene00000281", "sbo": "SBO:0000243", "uniprot": "Q27504"}, "name": "cah-3", "id": "WBGene00000281"}, {"annotation": {"kegg.genes": "CELE_F54D8.4", "wormbase": "WBGene00000279", "sbo": "SBO:0000243", "uniprot": "Q20781"}, "name": "cah-1", "id": "WBGene00000279"}, {"annotation": {"kegg.genes": "CELE_T28F2.3", "wormbase": "WBGene00000284", "sbo": "SBO:0000243", "uniprot": "O02637"}, "name": "cah-6", "id": "WBGene00000284"}, {"annotation": {"kegg.genes": "CELE_D2096.4", "wormbase": "WBGene00005019", "sbo": "SBO:0000243", "uniprot": "G5EF65"}, "name": "sqv-1", "id": "WBGene00005019"}, {"annotation": {"kegg.genes": "CELE_R01E6.3", "wormbase": "WBGene00000282", "sbo": "SBO:0000243", "uniprot": ["Q8WQD8", "Q21614"]}, "name": "cah-4", "id": "WBGene00000282"}, {"annotation": {"kegg.genes": "CELE_R173.1", "wormbase": "WBGene00000283", "sbo": "SBO:0000243", "uniprot": "Q10462"}, "name": "cah-5", "id": "WBGene00000283"}, {"annotation": {"kegg.genes": "CELE_C54G4.8", "wormbase": "WBGene00000869", "sbo": "SBO:0000243", "uniprot": "Q18853"}, "name": "cyc-1", "id": "WBGene00000869"}, {"annotation": {"kegg.genes": "CELE_Y47G6A.6", "wormbase": "WBGene00021636", "sbo": "SBO:0000243", "uniprot": "Q9N3S7"}, "name": "pcaf-1", "id": "WBGene00021636"}, {"annotation": {"kegg.genes": "CELE_Y71F9AL.18", "wormbase": "WBGene00004049", "sbo": "SBO:0000243", "uniprot": "Q9N4H4"}, "name": "parp-1", "id": "WBGene00004049"}, {"annotation": {"kegg.genes": "CELE_M04D5.1", "wormbase": "WBGene00014807", "sbo": "SBO:0000243", "uniprot": "H2FLL2"}, "name": "M04D5.1", "id": "WBGene00014807"}, {"annotation": {"kegg.genes": "CELE_C10C5.3", "wormbase": "WBGene00007507", "sbo": "SBO:0000243", "uniprot": "Q17898"}, "name": "C10C5.3", "id": "WBGene00007507"}, {"annotation": {"kegg.genes": "CELE_K07B1.3", "wormbase": "WBGene00006729", "sbo": "SBO:0000243", "uniprot": "O01883"}, "name": "ucp-4", "id": "WBGene00006729"}, {"annotation": {"kegg.genes": "CELE_R53.2", "wormbase": "WBGene00011272", "sbo": "SBO:0000243", "uniprot": "Q22018"}, "name": "dtmk-1", "id": "WBGene00011272"}, {"annotation": {"kegg.genes": "CELE_H23N18.3", "wormbase": "WBGene00019234", "sbo": "SBO:0000243", "uniprot": "Q9TXZ4"}, "name": "ugt-8", "id": "WBGene00019234"}, {"annotation": {"kegg.genes": "CELE_T19H12.1", "wormbase": "WBGene00020587", "sbo": "SBO:0000243", "uniprot": ["H2KZ88", "O01617"]}, "name": "ugt-9", "id": "WBGene00020587"}, {"annotation": {"kegg.genes": "CELE_ZC455.4", "wormbase": "WBGene00013904", "sbo": "SBO:0000243", "uniprot": "Q23334"}, "name": "ugt-6", "id": "WBGene00013904"}, {"annotation": {"kegg.genes": "CELE_C13D9.9", "wormbase": "WBGene00015739", "sbo": "SBO:0000243", "uniprot": "O16243"}, "name": "ugt-7", "id": "WBGene00015739"}, {"annotation": {"kegg.genes": "CELE_ZC455.5", "wormbase": "WBGene00013905", "sbo": "SBO:0000243", "uniprot": "Q23335"}, "name": "ugt-4", "id": "WBGene00013905"}, {"annotation": {"kegg.genes": "CELE_ZC455.6", "wormbase": "WBGene00013906", "sbo": "SBO:0000243", "uniprot": ["Q8I4B6", "Q23336"]}, "name": "ugt-5", "id": "WBGene00013906"}, {"annotation": {"kegg.genes": "CELE_AC3.8", "wormbase": "WBGene00007073", "sbo": "SBO:0000243", "uniprot": "Q17404"}, "name": "ugt-2", "id": "WBGene00007073"}, {"annotation": {"kegg.genes": "CELE_ZC455.3", "wormbase": "WBGene00013903", "sbo": "SBO:0000243", "uniprot": "Q23333"}, "name": "ugt-3", "id": "WBGene00013903"}, {"annotation": {"kegg.genes": "CELE_AC3.7", "wormbase": "WBGene00007072", "sbo": "SBO:0000243", "uniprot": "Q17403"}, "name": "ugt-1", "id": "WBGene00007072"}, {"annotation": {"kegg.genes": "CELE_Y71G12B.10", "wormbase": "WBGene00022150", "sbo": "SBO:0000243", "uniprot": "Q95XN1"}, "name": "Y71G12B.10", "id": "WBGene00022150"}, {"annotation": {"kegg.genes": "CELE_C36B1.3", "wormbase": "WBGene00007971", "sbo": "SBO:0000243", "uniprot": "Q93338"}, "name": "rpb-3", "id": "WBGene00007971"}, {"annotation": {"kegg.genes": "CELE_C32E12.2", "wormbase": "WBGene00016328", "sbo": "SBO:0000243", "uniprot": "P91119"}, "name": "pde-5", "id": "WBGene00016328"}, {"annotation": {"kegg.genes": "CELE_R153.1", "wormbase": "WBGene00020114", "sbo": "SBO:0000243", "uniprot": ["Q2V4U0", "Q22000"]}, "name": "pde-4", "id": "WBGene00020114"}, {"annotation": {"kegg.genes": "CELE_C06A1.5", "wormbase": "WBGene00007355", "sbo": "SBO:0000243", "uniprot": "Q17684"}, "name": "rpb-6", "id": "WBGene00007355"}, {"annotation": {"kegg.genes": "CELE_Y54E10BR.6", "wormbase": "WBGene00021845", "sbo": "SBO:0000243", "uniprot": "Q9N3C9"}, "name": "rpb-7", "id": "WBGene00021845"}, {"annotation": {"kegg.genes": "CELE_F10D2.8", "wormbase": "WBGene00017334", "sbo": "SBO:0000243", "uniprot": "O16917"}, "name": "F10D2.8", "id": "WBGene00017334"}, {"annotation": {"kegg.genes": "CELE_H27M09.2", "wormbase": "WBGene00019246", "sbo": "SBO:0000243", "uniprot": "Q9N5K2"}, "name": "rpb-5", "id": "WBGene00019246"}, {"annotation": {"kegg.genes": "CELE_Y24D9A.2", "wormbase": "WBGene00021282", "sbo": "SBO:0000243", "uniprot": "Q966C5"}, "name": "set-21", "id": "WBGene00021282"}, {"annotation": {"kegg.genes": "CELE_K06A1.6", "wormbase": "WBGene00019428", "sbo": "SBO:0000243", "uniprot": "Q10024"}, "name": "dgk-5", "id": "WBGene00019428"}, {"annotation": {"kegg.genes": "CELE_Y41D4B.12", "wormbase": "WBGene00021515", "sbo": "SBO:0000243", "uniprot": "Q95Y12"}, "name": "set-23", "id": "WBGene00021515"}, {"annotation": {"kegg.genes": "CELE_Y97E10AR.5", "wormbase": "WBGene00022400", "sbo": "SBO:0000243", "uniprot": "Q965S0"}, "name": "rpb-9", "id": "WBGene00022400"}, {"annotation": {"kegg.genes": "CELE_Y43C5A.5", "wormbase": "WBGene00006568", "sbo": "SBO:0000243", "uniprot": ["F3Y5P8", "G5EEZ5"]}, "name": "thk-1", "id": "WBGene00006568"}, {"annotation": {"kegg.genes": "CELE_D2096.3", "wormbase": "WBGene00017071", "sbo": "SBO:0000243", "uniprot": "Q19004"}, "name": "aagr-1", "id": "WBGene00017071"}, {"annotation": {"kegg.genes": "CELE_F01G10.1", "wormbase": "WBGene00008506", "sbo": "SBO:0000243", "uniprot": "O17759"}, "name": "tkt-1", "id": "WBGene00008506"}, {"annotation": {"kegg.genes": "CELE_ZC506.3", "wormbase": "WBGene00013920", "sbo": "SBO:0000243", "uniprot": "Q09643"}, "name": "pssy-1", "id": "WBGene00013920"}, {"annotation": {"kegg.genes": "CELE_T02G5.7", "wormbase": "WBGene00020166", "sbo": "SBO:0000243", "uniprot": "Q22101"}, "name": "T02G5.7", "id": "WBGene00020166"}, {"annotation": {"kegg.genes": "CELE_R53.4", "wormbase": "WBGene00011273", "sbo": "SBO:0000243", "uniprot": "Q22021"}, "name": "R53.4", "id": "WBGene00011273"}, {"annotation": {"kegg.genes": "CELE_K02F3.6", "wormbase": "WBGene00019329", "sbo": "SBO:0000243", "uniprot": "G5EBI4"}, "name": "ceeh-1", "id": "WBGene00019329"}, {"annotation": {"kegg.genes": "CELE_F32D8.12", "wormbase": "WBGene00009334", "sbo": "SBO:0000243", "uniprot": ["Q8I4K2", "Q7JLJ0", "Q7JLI9"]}, "name": "F32D8.12", "id": "WBGene00009334"}, {"annotation": {"kegg.genes": "CELE_F32D8.13", "wormbase": "WBGene00009335", "sbo": "SBO:0000243", "uniprot": ["I2HAD9", "Q86NH2"]}, "name": "F32D8.13", "id": "WBGene00009335"}, {"annotation": {"kegg.genes": "CELE_C15F1.7", "wormbase": "WBGene00004930", "sbo": "SBO:0000243", "uniprot": "P34697"}, "name": "sod-1", "id": "WBGene00004930"}, {"annotation": {"kegg.genes": "CELE_K11C4.4", "wormbase": "WBGene00003844", "sbo": "SBO:0000243", "uniprot": "P41931"}, "name": "odc-1", "id": "WBGene00003844"}, {"annotation": {"kegg.genes": "CELE_Y48G1C.4", "wormbase": "WBGene00021677", "sbo": "SBO:0000243", "uniprot": "Q9BL79"}, "name": "pgs-1", "id": "WBGene00021677"}, {"annotation": {"kegg.genes": "CELE_Y51A2D.13", "wormbase": "WBGene00013080", "sbo": "SBO:0000243", "uniprot": ["Q9XXR6", "Q8I4C7"]}, "name": "Y51A2D.13", "id": "WBGene00013080"}, {"annotation": {"kegg.genes": "CELE_C47D12.6", "wormbase": "WBGene00006617", "sbo": "SBO:0000243", "uniprot": ["Q86D21", "P52709"]}, "name": "tars-1", "id": "WBGene00006617"}, {"annotation": {"kegg.genes": "CELE_C15H9.7", "wormbase": "WBGene00015802", "sbo": "SBO:0000243", "uniprot": "Q18026"}, "name": "kynu-1", "id": "WBGene00015802"}, {"annotation": {"kegg.genes": "CELE_R12C12.1", "wormbase": "WBGene00020022", "sbo": "SBO:0000243", "uniprot": ["Q86LS6", "Q21962"]}, "name": "gldc-1", "id": "WBGene00020022"}, {"annotation": {"kegg.genes": "CELE_ZK1127.10", "wormbase": "WBGene00022856", "sbo": "SBO:0000243", "uniprot": "P55216"}, "name": "cth-2", "id": "WBGene00022856"}, {"annotation": {"kegg.genes": "CELE_C29F7.3", "wormbase": "WBGene00007812", "sbo": "SBO:0000243", "uniprot": "O17622"}, "name": "C29F7.3", "id": "WBGene00007812"}, {"annotation": {"kegg.genes": "CELE_F52H3.1", "wormbase": "WBGene00002497", "sbo": "SBO:0000243", "uniprot": "Q20679"}, "name": "let-268", "id": "WBGene00002497"}, {"annotation": {"kegg.genes": "CELE_ZK892.2", "wormbase": "WBGene00003773", "sbo": "SBO:0000243", "uniprot": "Q23655"}, "name": "nlt-1", "id": "WBGene00003773"}, {"annotation": {"kegg.genes": "CELE_T12A2.1", "wormbase": "WBGene00020436", "sbo": "SBO:0000243", "uniprot": "Q22419"}, "name": "T12A2.1", "id": "WBGene00020436"}, {"annotation": {"kegg.genes": "CELE_C33C12.3", "wormbase": "WBGene00016335", "sbo": "SBO:0000243", "uniprot": "O16580"}, "name": "gba-1", "id": "WBGene00016335"}, {"annotation": {"kegg.genes": "CELE_C14B1.1", "wormbase": "WBGene00003962", "sbo": "SBO:0000243", "uniprot": "Q17967"}, "name": "pdi-1", "id": "WBGene00003962"}, {"annotation": {"kegg.genes": "CELE_C34F11.3", "wormbase": "WBGene00016415", "sbo": "SBO:0000243", "uniprot": ["D7SFL2", "H2KZ18", "H2KZ19"]}, "name": "ampd-1", "id": "WBGene00016415"}, {"annotation": {"kegg.genes": "CELE_T03F6.3", "wormbase": "WBGene00011399", "sbo": "SBO:0000243", "uniprot": "Q9XVJ2"}, "name": "T03F6.3", "id": "WBGene00011399"}, {"annotation": {"kegg.genes": "CELE_T25B9.9", "wormbase": "WBGene00012015", "sbo": "SBO:0000243", "uniprot": "Q17761"}, "name": "T25B9.9", "id": "WBGene00012015"}, {"annotation": {"kegg.genes": "CELE_F20C5.1", "wormbase": "WBGene00004051", "sbo": "SBO:0000243", "uniprot": ["Q867X0", "A5JYS4", "Q5WRP7", "F5GU97"]}, "name": "parg-1", "id": "WBGene00004051"}, {"annotation": {"kegg.genes": "CELE_H23L24.5", "wormbase": "WBGene00004052", "sbo": "SBO:0000243", "uniprot": "Q9N5L4"}, "name": "parg-2", "id": "WBGene00004052"}, {"annotation": {"kegg.genes": "CELE_R05G6.5", "wormbase": "WBGene00019899", "sbo": "SBO:0000243", "uniprot": "Q21753"}, "name": "R05G6.5", "id": "WBGene00019899"}, {"annotation": {"kegg.genes": "CELE_Y37D8A.14", "wormbase": "WBGene00012553", "sbo": "SBO:0000243", "uniprot": "P55954"}, "name": "cco-2", "id": "WBGene00012553"}, {"annotation": {"kegg.genes": "CELE_T25E12.5", "wormbase": "WBGene00012020", "sbo": "SBO:0000243", "uniprot": "O45819"}, "name": "gyg-2", "id": "WBGene00012020"}, {"annotation": {"kegg.genes": "CELE_M176.2", "wormbase": "WBGene00010941", "sbo": "SBO:0000243", "uniprot": "Q21549"}, "name": "gss-1", "id": "WBGene00010941"}, {"annotation": {"kegg.genes": "CELE_T20H4.3", "wormbase": "WBGene00004189", "sbo": "SBO:0000243", "uniprot": ["Q22620", "Q65ZK5"]}, "name": "pars-1", "id": "WBGene00004189"}, {"annotation": {"kegg.genes": "CELE_C15H11.8", "wormbase": "WBGene00007616", "sbo": "SBO:0000243", "uniprot": "O17587"}, "name": "rpoa-12", "id": "WBGene00007616"}, {"annotation": {"kegg.genes": "CELE_B0205.6", "wormbase": "WBGene00015021", "sbo": "SBO:0000243", "uniprot": "O61741"}, "name": "B0205.6", "id": "WBGene00015021"}, {"annotation": {"kegg.genes": "CELE_K08H10.4", "wormbase": "WBGene00010697", "sbo": "SBO:0000243", "uniprot": "Q9XU84"}, "name": "uda-1", "id": "WBGene00010697"}, {"annotation": {"kegg.genes": "CELE_F40F8.1", "wormbase": "WBGene00009575", "sbo": "SBO:0000243", "uniprot": "Q20230"}, "name": "F40F8.1", "id": "WBGene00009575"}, {"annotation": {"kegg.genes": "CELE_T06D8.5", "wormbase": "WBGene00011526", "sbo": "SBO:0000243", "uniprot": "Q22251"}, "name": "cox-15", "id": "WBGene00011526"}, {"annotation": {"kegg.genes": "CELE_ZC416.6", "wormbase": "WBGene00022610", "sbo": "SBO:0000243", "uniprot": "O44183"}, "name": "ZC416.6", "id": "WBGene00022610"}, {"annotation": {"kegg.genes": "CELE_R05F9.6", "wormbase": "WBGene00019890", "sbo": "SBO:0000243", "uniprot": "Q21742"}, "name": "R05F9.6", "id": "WBGene00019890"}, {"annotation": {"kegg.genes": "CELE_BE10.2", "wormbase": "WBGene00007210", "sbo": "SBO:0000243", "uniprot": "O17554"}, "name": "agmo-1", "id": "WBGene00007210"}, {"annotation": {"kegg.genes": "CELE_W03D8.8", "wormbase": "WBGene00020989", "sbo": "SBO:0000243", "uniprot": "O45003"}, "name": "W03D8.8", "id": "WBGene00020989"}, {"annotation": {"kegg.genes": "CELE_R05D11.9", "wormbase": "WBGene00011037", "sbo": "SBO:0000243", "uniprot": "Q95ZR2"}, "name": "R05D11.9", "id": "WBGene00011037"}, {"annotation": {"kegg.genes": "CELE_T02E1.5", "wormbase": "WBGene00000967", "sbo": "SBO:0000243", "uniprot": ["A5JYX6", "A5JYX5", "A5JYX4"]}, "name": "dhs-3", "id": "WBGene00000967"}, {"annotation": {"kegg.genes": "CELE_C46F11.2", "wormbase": "WBGene00008117", "sbo": "SBO:0000243", "uniprot": ["Q86DB5", "Q93379"]}, "name": "gsr-1", "id": "WBGene00008117"}, {"annotation": {"kegg.genes": "CELE_Y43F4B.5", "wormbase": "WBGene00012803", "sbo": "SBO:0000243", "uniprot": ["Q86DA0", "O45934"]}, "name": "Y43F4B.5", "id": "WBGene00012803"}, {"annotation": {"kegg.genes": "CELE_F44G3.2", "wormbase": "WBGene00009706", "sbo": "SBO:0000243", "uniprot": "O45518"}, "name": "argk-1", "id": "WBGene00009706"}, {"annotation": {"kegg.genes": "CELE_ZK563.6", "wormbase": "WBGene00022770", "sbo": "SBO:0000243", "uniprot": "Q23534"}, "name": "acp-1", "id": "WBGene00022770"}, {"annotation": {"kegg.genes": "CELE_F09F3.9", "wormbase": "WBGene00008629", "sbo": "SBO:0000243", "uniprot": "G5EG54"}, "name": "cpt-5", "id": "WBGene00008629"}, {"annotation": {"kegg.genes": "CELE_C37H5.13", "wormbase": "WBGene00016511", "sbo": "SBO:0000243", "uniprot": ["H2KZ87", "Q95Q68", "A3RMS7"]}, "name": "C37H5.13", "id": "WBGene00016511"}, {"annotation": {"kegg.genes": "CELE_C25H3.9", "wormbase": "WBGene00016118", "sbo": "SBO:0000243", "uniprot": ["H2KYV1", "D7SFJ4"]}, "name": "C25H3.9", "id": "WBGene00016118"}, {"annotation": {"kegg.genes": "CELE_R05G6.8", "wormbase": "WBGene00004039", "sbo": "SBO:0000243", "uniprot": "Q21754"}, "name": "plc-4", "id": "WBGene00004039"}, {"annotation": {"kegg.genes": "CELE_F59G1.7", "wormbase": "WBGene00001486", "sbo": "SBO:0000243", "uniprot": "Q9TY03"}, "name": "frh-1", "id": "WBGene00001486"}, {"annotation": {"kegg.genes": "CELE_F31B12.1", "wormbase": "WBGene00004036", "sbo": "SBO:0000243", "uniprot": ["G5EFI5", "G5EFI8", "G5EFG8", "G5EEJ6", "G5ED55", "G5EEI0"]}, "name": "plc-1", "id": "WBGene00004036"}, {"annotation": {"kegg.genes": "CELE_T01E8.3", "wormbase": "WBGene00004038", "sbo": "SBO:0000243", "uniprot": "Q22070"}, "name": "plc-3", "id": "WBGene00004038"}, {"annotation": {"kegg.genes": "CELE_Y75B12B.6", "wormbase": "WBGene00004037", "sbo": "SBO:0000243", "uniprot": "Q9XWB7"}, "name": "plc-2", "id": "WBGene00004037"}, {"annotation": {"kegg.genes": "CELE_C06H2.4", "wormbase": "WBGene00007388", "sbo": "SBO:0000243", "uniprot": "Q17766"}, "name": "folt-1", "id": "WBGene00007388"}, {"annotation": {"kegg.genes": "CELE_R06C7.5", "wormbase": "WBGene00011064", "sbo": "SBO:0000243", "uniprot": "Q21774"}, "name": "adsl-1", "id": "WBGene00011064"}, {"annotation": {"kegg.genes": "CELE_C54F6.14", "wormbase": "WBGene00001500", "sbo": "SBO:0000243", "uniprot": "O16453"}, "name": "ftn-1", "id": "WBGene00001500"}, {"annotation": {"kegg.genes": "CELE_C26D10.4", "wormbase": "WBGene00007745", "sbo": "SBO:0000243", "uniprot": "Q18214"}, "name": "C26D10.4", "id": "WBGene00007745"}, {"annotation": {"kegg.genes": "CELE_T19H5.3", "wormbase": "WBGene00011848", "sbo": "SBO:0000243", "uniprot": "Q22597"}, "name": "chil-27", "id": "WBGene00011848"}, {"annotation": {"kegg.genes": "CELE_T10D4.3", "wormbase": "WBGene00020407", "sbo": "SBO:0000243", "uniprot": "Q9TZF2"}, "name": "chil-24", "id": "WBGene00020407"}, {"annotation": {"kegg.genes": "CELE_T19H5.1", "wormbase": "WBGene00011846", "sbo": "SBO:0000243", "uniprot": "Q22598"}, "name": "chil-25", "id": "WBGene00011846"}, {"annotation": {"kegg.genes": "CELE_R09D1.10", "wormbase": "WBGene00011166", "sbo": "SBO:0000243", "uniprot": "Q21866"}, "name": "chil-22", "id": "WBGene00011166"}, {"annotation": {"kegg.genes": "CELE_R09D1.11", "wormbase": "WBGene00011167", "sbo": "SBO:0000243", "uniprot": "G5EBF8"}, "name": "chil-23", "id": "WBGene00011167"}, {"annotation": {"kegg.genes": "CELE_R09D1.7", "wormbase": "WBGene00011163", "sbo": "SBO:0000243", "uniprot": "Q21863"}, "name": "chil-20", "id": "WBGene00011163"}, {"annotation": {"kegg.genes": "CELE_R09D1.8", "wormbase": "WBGene00011164", "sbo": "SBO:0000243", "uniprot": "Q21864"}, "name": "chil-21", "id": "WBGene00011164"}, {"annotation": {"kegg.genes": "CELE_H06O01.1", "wormbase": "WBGene00003964", "sbo": "SBO:0000243", "uniprot": "G5ED07"}, "name": "pdi-3", "id": "WBGene00003964"}, {"annotation": {"kegg.genes": "CELE_C07A12.4", "wormbase": "WBGene00003963", "sbo": "SBO:0000243", "uniprot": ["A3RMS2", "G8JY07", "Q17770"]}, "name": "pdi-2", "id": "WBGene00003963"}, {"annotation": {"kegg.genes": "CELE_C46C11.1", "wormbase": "WBGene00016704", "sbo": "SBO:0000243", "uniprot": ["Q966P1", "E7FM69"]}, "name": "hosl-1", "id": "WBGene00016704"}, {"annotation": {"kegg.genes": "CELE_T05C3.6", "wormbase": "WBGene00020256", "sbo": "SBO:0000243", "uniprot": ["A6PVA4", "H2KZ05"]}, "name": "T05C3.6", "id": "WBGene00020256"}, {"annotation": {"kegg.genes": "CELE_B0403.4", "wormbase": "WBGene00015168", "sbo": "SBO:0000243", "uniprot": "Q11067"}, "name": "pdi-6", "id": "WBGene00015168"}, {"annotation": {"kegg.genes": "CELE_F49E2.1", "wormbase": "WBGene00009885", "sbo": "SBO:0000243", "uniprot": "Q20624"}, "name": "F49E2.1", "id": "WBGene00009885"}, {"annotation": {"kegg.genes": "CELE_C55H1.1", "wormbase": "WBGene00016959", "sbo": "SBO:0000243", "uniprot": "Q18872"}, "name": "C55H1.1", "id": "WBGene00016959"}, {"annotation": {"kegg.genes": "CELE_K06A4.5", "wormbase": "WBGene00010595", "sbo": "SBO:0000243", "uniprot": "Q19341"}, "name": "haao-1", "id": "WBGene00010595"}, {"annotation": {"kegg.genes": "CELE_F57B10.7", "wormbase": "WBGene00006607", "sbo": "SBO:0000243", "uniprot": "G5EC40"}, "name": "tre-1", "id": "WBGene00006607"}, {"annotation": {"kegg.genes": "CELE_Y46G5A.31", "wormbase": "WBGene00001793", "sbo": "SBO:0000243", "uniprot": "Q9U2D9"}, "name": "gsy-1", "id": "WBGene00001793"}, {"annotation": {"kegg.genes": "CELE_Y48E1B.3", "wormbase": "WBGene00013002", "sbo": "SBO:0000243", "uniprot": ["B7WNB2", "B7WNB0", "B7WNB1", "O18197"]}, "name": "Y48E1B.3", "id": "WBGene00013002"}, {"annotation": {"kegg.genes": "CELE_ZK632.4", "wormbase": "WBGene00014013", "sbo": "SBO:0000243", "uniprot": "P34650"}, "name": "ZK632.4", "id": "WBGene00014013"}, {"annotation": {"kegg.genes": "CELE_F36H9.3", "wormbase": "WBGene00000976", "sbo": "SBO:0000243", "uniprot": "O16619"}, "name": "dhs-13", "id": "WBGene00000976"}, {"annotation": {"kegg.genes": "CELE_T24D1.4", "wormbase": "WBGene00007043", "sbo": "SBO:0000243", "uniprot": "O02332"}, "name": "tag-179", "id": "WBGene00007043"}, {"annotation": {"kegg.genes": "CELE_F58H1.1", "wormbase": "WBGene00010284", "sbo": "SBO:0000243", "uniprot": "Q2PJ74"}, "name": "aman-2", "id": "WBGene00010284"}, {"annotation": {"kegg.genes": "CELE_T11F9.11", "wormbase": "WBGene00000982", "sbo": "SBO:0000243", "uniprot": "Q22392"}, "name": "dhs-19", "id": "WBGene00000982"}, {"annotation": {"kegg.genes": "CELE_H24K24.3", "wormbase": "WBGene00019240", "sbo": "SBO:0000243", "uniprot": "Q17335"}, "name": "H24K24.3", "id": "WBGene00019240"}, {"annotation": {"kegg.genes": "CELE_F27E5.1", "wormbase": "WBGene00009192", "sbo": "SBO:0000243", "uniprot": "Q09551"}, "name": "asah-2", "id": "WBGene00009192"}, {"annotation": {"kegg.genes": "CELE_H24K24.5", "wormbase": "WBGene00001480", "sbo": "SBO:0000243", "uniprot": "G5ED43"}, "name": "fmo-5", "id": "WBGene00001480"}, {"annotation": {"kegg.genes": "CELE_K11D2.2", "wormbase": "WBGene00010769", "sbo": "SBO:0000243", "uniprot": "O45686"}, "name": "asah-1", "id": "WBGene00010769"}, {"annotation": {"kegg.genes": "CELE_F08C6.2", "wormbase": "WBGene00017241", "sbo": "SBO:0000243", "uniprot": ["Q3HKC4", "P49583"]}, "name": "pcyt-1", "id": "WBGene00017241"}, {"annotation": {"kegg.genes": "CELE_F32D1.2", "wormbase": "WBGene00017982", "sbo": "SBO:0000243", "uniprot": "O16298"}, "name": "hpo-18", "id": "WBGene00017982"}, {"annotation": {"kegg.genes": "CELE_T03D8.5", "wormbase": "WBGene00001547", "sbo": "SBO:0000243", "uniprot": "Q9XTY1"}, "name": "gcy-22", "id": "WBGene00001547"}, {"annotation": {"kegg.genes": "CELE_T26C12.4", "wormbase": "WBGene00001548", "sbo": "SBO:0000243", "uniprot": "G5EEE9"}, "name": "gcy-23", "id": "WBGene00001548"}, {"annotation": {"kegg.genes": "CELE_C30H6.7", "wormbase": "WBGene00007824", "sbo": "SBO:0000243", "uniprot": "O45279"}, "name": "dlat-2", "id": "WBGene00007824"}, {"annotation": {"kegg.genes": "CELE_F46H6.2", "wormbase": "WBGene00000959", "sbo": "SBO:0000243", "uniprot": ["Q7Z299", "Q7Z2A0", "H2KYI9"]}, "name": "dgk-2", "id": "WBGene00000959"}, {"annotation": {"kegg.genes": "CELE_T01A4.1", "wormbase": "WBGene00020131", "sbo": "SBO:0000243", "uniprot": ["Q86GV3", "Q965F7", "Q965F8", "H2L0J9"]}, "name": "gcy-28", "id": "WBGene00020131"}, {"annotation": {"kegg.genes": "CELE_C04H5.3", "wormbase": "WBGene00007314", "sbo": "SBO:0000243", "uniprot": "O62026"}, "name": "gcy-29", "id": "WBGene00007314"}, {"annotation": {"kegg.genes": "CELE_Y105E8A.10", "wormbase": "WBGene00013670", "sbo": "SBO:0000243", "uniprot": ["Q6EUT3", "Q6EUT4", "Q8WQB2"]}, "name": "hpo-13", "id": "WBGene00013670"}, {"annotation": {"kegg.genes": "CELE_B0025.1", "wormbase": "WBGene00006932", "sbo": "SBO:0000243", "uniprot": ["Q9TXI7", "Q5TYK9", "Q9TXI6"]}, "name": "vps-34", "id": "WBGene00006932"}, {"annotation": {"kegg.genes": "CELE_ZC449.6", "wormbase": "WBGene00022616", "sbo": "SBO:0000243", "uniprot": "A4UVJ7"}, "name": "hsd-3", "id": "WBGene00022616"}, {"annotation": {"kegg.genes": "CELE_ZC8.1", "wormbase": "WBGene00022498", "sbo": "SBO:0000243", "uniprot": "Q23086"}, "name": "hsd-2", "id": "WBGene00022498"}, {"annotation": {"kegg.genes": "CELE_Y6B3B.11", "wormbase": "WBGene00012394", "sbo": "SBO:0000243", "uniprot": "Q9XWF0"}, "name": "hsd-1", "id": "WBGene00012394"}, {"annotation": {"kegg.genes": "CELE_F58F9.1", "wormbase": "WBGene00019055", "sbo": "SBO:0000243"}, "name": "F58F9.1", "id": "WBGene00019055"}, {"annotation": {"kegg.genes": "CELE_F22B7.6", "wormbase": "WBGene00017696", "sbo": "SBO:0000243", "uniprot": "P34409"}, "name": "polk-1", "id": "WBGene00017696"}, {"annotation": {"kegg.genes": "CELE_ZK1058.6", "wormbase": "WBGene00014206", "sbo": "SBO:0000243", "uniprot": "Q23384"}, "name": "nit-1", "id": "WBGene00014206"}, {"annotation": {"kegg.genes": "CELE_K04C2.2", "wormbase": "WBGene00019380", "sbo": "SBO:0000243", "uniprot": "Q21210"}, "name": "K04C2.2", "id": "WBGene00019380"}, {"annotation": {"kegg.genes": "ND6", "wormbase": "WBGene00010957", "sbo": "SBO:0000243", "uniprot": ["P24885", "B1PEV9"]}, "name": "nduo-6", "id": "WBGene00010957"}, {"annotation": {"kegg.genes": "CELE_ZK370.4", "wormbase": "WBGene00022718", "sbo": "SBO:0000243", "uniprot": "Q02331"}, "name": "ZK370.4", "id": "WBGene00022718"}, {"annotation": {"kegg.genes": "CELE_T05D4.1", "wormbase": "WBGene00011474", "sbo": "SBO:0000243", "uniprot": "P54216"}, "name": "aldo-1", "id": "WBGene00011474"}, {"annotation": {"kegg.genes": "CELE_R11A8.3", "wormbase": "WBGene00011238", "sbo": "SBO:0000243", "uniprot": "Q21922"}, "name": "ugt-59", "id": "WBGene00011238"}, {"annotation": {"kegg.genes": "CELE_ZC513.5", "wormbase": "WBGene00022629", "sbo": "SBO:0000243", "uniprot": "Q23361"}, "name": "ZC513.5", "id": "WBGene00022629"}, {"annotation": {"kegg.genes": "CELE_F01F1.12", "wormbase": "WBGene00017166", "sbo": "SBO:0000243", "uniprot": ["P46563", "G8JY45"]}, "name": "aldo-2", "id": "WBGene00017166"}, {"annotation": {"kegg.genes": "CELE_T25B9.7", "wormbase": "WBGene00012013", "sbo": "SBO:0000243", "uniprot": "Q22770"}, "name": "ugt-54", "id": "WBGene00012013"}, {"annotation": {"kegg.genes": "CELE_T04H1.7", "wormbase": "WBGene00011452", "sbo": "SBO:0000243", "uniprot": "Q22180"}, "name": "ugt-55", "id": "WBGene00011452"}, {"annotation": {"kegg.genes": "CELE_T04H1.8", "wormbase": "WBGene00011453", "sbo": "SBO:0000243", "uniprot": "Q22181"}, "name": "ugt-56", "id": "WBGene00011453"}, {"annotation": {"kegg.genes": "CELE_T07C5.1", "wormbase": "WBGene00011564", "sbo": "SBO:0000243", "uniprot": "Q22295"}, "name": "ugt-50", "id": "WBGene00011564"}, {"annotation": {"kegg.genes": "CELE_C03A7.11", "wormbase": "WBGene00015369", "sbo": "SBO:0000243", "uniprot": "O16506"}, "name": "ugt-51", "id": "WBGene00015369"}, {"annotation": {"kegg.genes": "CELE_F56B3.7", "wormbase": "WBGene00018931", "sbo": "SBO:0000243", "uniprot": "O45109"}, "name": "ugt-52", "id": "WBGene00018931"}, {"annotation": {"kegg.genes": "CELE_T03D3.1", "wormbase": "WBGene00020182", "sbo": "SBO:0000243", "uniprot": "O16988"}, "name": "ugt-53", "id": "WBGene00020182"}, {"annotation": {"kegg.genes": "CELE_F09G2.8", "wormbase": "WBGene00017316", "sbo": "SBO:0000243", "uniprot": "O17405"}, "name": "F09G2.8", "id": "WBGene00017316"}, {"annotation": {"kegg.genes": "CELE_Y6B3B.5", "wormbase": "WBGene00012390", "sbo": "SBO:0000243", "uniprot": ["Q9XWE8", "Q5ZEQ3"]}, "name": "gpap-1", "id": "WBGene00012390"}, {"annotation": {"kegg.genes": "CELE_F23C8.5", "wormbase": "WBGene00017734", "sbo": "SBO:0000243", "uniprot": "Q9TXI4"}, "name": "F23C8.5", "id": "WBGene00017734"}, {"annotation": {"kegg.genes": "CELE_F28B3.9", "wormbase": "WBGene00017888", "sbo": "SBO:0000243", "uniprot": "Q95R12"}, "name": "acl-11", "id": "WBGene00017888"}, {"annotation": {"kegg.genes": "CELE_C12C8.2", "wormbase": "WBGene00007533", "sbo": "SBO:0000243", "uniprot": ["A5JYW2", "O02215"]}, "name": "cbl-1", "id": "WBGene00007533"}, {"annotation": {"kegg.genes": "CELE_C42C1.11", "wormbase": "WBGene00016589", "sbo": "SBO:0000243", "uniprot": ["A3QMC2", "A3QMC1", "G5EFT4"]}, "name": "C42C1.11", "id": "WBGene00016589"}, {"annotation": {"kegg.genes": "CELE_F53F4.5", "wormbase": "WBGene00001479", "sbo": "SBO:0000243", "uniprot": "G5EDG8"}, "name": "fmo-4", "id": "WBGene00001479"}, {"annotation": {"kegg.genes": "CELE_F53A3.2", "wormbase": "WBGene00018721", "sbo": "SBO:0000243", "uniprot": "G5EFY1"}, "name": "polh-1", "id": "WBGene00018721"}, {"annotation": {"kegg.genes": "CELE_Y69A2AR.18", "wormbase": "WBGene00022089", "sbo": "SBO:0000243", "uniprot": ["Q95XI9", "Q86DM7", "Q95XJ0"]}, "name": "Y69A2AR.18", "id": "WBGene00022089"}, {"annotation": {"kegg.genes": "CELE_D2063.1", "wormbase": "WBGene00017060", "sbo": "SBO:0000243", "uniprot": "Q9UAT1"}, "name": "D2063.1", "id": "WBGene00017060"}, {"annotation": {"kegg.genes": "CELE_K07B1.5", "wormbase": "WBGene00019465", "sbo": "SBO:0000243", "uniprot": ["Q95R03", "O01882"]}, "name": "acl-14", "id": "WBGene00019465"}, {"annotation": {"kegg.genes": "CELE_F29C4.2", "wormbase": "WBGene00017926", "sbo": "SBO:0000243", "uniprot": "O76367"}, "name": "F29C4.2", "id": "WBGene00017926"}, {"annotation": {"kegg.genes": "CELE_ZK669.4", "wormbase": "WBGene00014054", "sbo": "SBO:0000243", "uniprot": "Q23571"}, "name": "dbt-1", "id": "WBGene00014054"}, {"annotation": {"kegg.genes": "CELE_F21H7.9", "wormbase": "WBGene00001545", "sbo": "SBO:0000243", "uniprot": "O62179"}, "name": "gcy-20", "id": "WBGene00001545"}, {"annotation": {"kegg.genes": "CELE_R04B5.9", "wormbase": "WBGene00011006", "sbo": "SBO:0000243", "uniprot": "Q21706"}, "name": "ugt-47", "id": "WBGene00011006"}, {"annotation": {"kegg.genes": "CELE_D2023.5", "wormbase": "WBGene00008409", "sbo": "SBO:0000243", "uniprot": "O17730"}, "name": "mpst-1", "id": "WBGene00008409"}, {"annotation": {"kegg.genes": "CELE_F22E5.3", "wormbase": "WBGene00001546", "sbo": "SBO:0000243", "uniprot": "O16715"}, "name": "gcy-21", "id": "WBGene00001546"}, {"annotation": {"kegg.genes": "CELE_C44E12.1", "wormbase": "WBGene00016657", "sbo": "SBO:0000243", "uniprot": "Q18621"}, "name": "C44E12.1", "id": "WBGene00016657"}, {"annotation": {"kegg.genes": "CELE_ZC416.8a", "wormbase": "WBGene00006756", "sbo": "SBO:0000243", "uniprot": "P34711"}, "name": "unc-17", "id": "WBGene00006756"}, {"annotation": {"kegg.genes": "CELE_F58A6.1", "wormbase": "WBGene00019022", "sbo": "SBO:0000243", "uniprot": "Q20959"}, "name": "F58A6.1", "id": "WBGene00019022"}, {"annotation": {"kegg.genes": "CELE_C44B7.12", "wormbase": "WBGene00016632", "sbo": "SBO:0000243", "uniprot": "Q8IG39"}, "name": "C44B7.12", "id": "WBGene00016632"}, {"annotation": {"kegg.genes": "CELE_T25D3.3", "wormbase": "WBGene00020797", "sbo": "SBO:0000243", "uniprot": "Q965I8"}, "name": "T25D3.3", "id": "WBGene00020797"}, {"annotation": {"kegg.genes": "CELE_K03H1.1", "wormbase": "WBGene00001603", "sbo": "SBO:0000243", "uniprot": "P34497"}, "name": "gln-2", "id": "WBGene00001603"}, {"annotation": {"kegg.genes": "CELE_T03F6.1", "wormbase": "WBGene00011398", "sbo": "SBO:0000243", "uniprot": "Q9XVJ3"}, "name": "qdpr-1", "id": "WBGene00011398"}, {"annotation": {"kegg.genes": "CELE_Y39A1A.19", "wormbase": "WBGene00001478", "sbo": "SBO:0000243", "uniprot": "G5ECJ8"}, "name": "fmo-3", "id": "WBGene00001478"}, {"annotation": {"kegg.genes": "CELE_ZK973.10", "wormbase": "WBGene00003061", "sbo": "SBO:0000243", "uniprot": "Q9N4L8"}, "name": "lpd-5", "id": "WBGene00003061"}, {"annotation": {"kegg.genes": "CELE_C42D4.8", "wormbase": "WBGene00004411", "sbo": "SBO:0000243", "uniprot": "Q18566"}, "name": "rpc-1", "id": "WBGene00004411"}, {"annotation": {"kegg.genes": "CELE_F55B11.1", "wormbase": "WBGene00010083", "sbo": "SBO:0000243", "uniprot": "O17892"}, "name": "xdh-1", "id": "WBGene00010083"}, {"annotation": {"kegg.genes": "CELE_R08E5.2", "wormbase": "WBGene00019962", "sbo": "SBO:0000243", "uniprot": ["O01592", "H2L0J5", "Q86NC6"]}, "name": "cysl-3", "id": "WBGene00019962"}, {"annotation": {"kegg.genes": "CELE_C06G3.7", "wormbase": "WBGene00015553", "sbo": "SBO:0000243"}, "name": "trxr-1", "id": "WBGene00015553"}, {"annotation": {"kegg.genes": "CELE_C49A9.8", "wormbase": "WBGene00016762", "sbo": "SBO:0000243"}, "name": "ugt-24", "id": "WBGene00016762"}, {"annotation": {"kegg.genes": "CELE_F23B12.6", "wormbase": "WBGene00006465", "sbo": "SBO:0000243", "uniprot": "Q19752"}, "name": "fntb-1", "id": "WBGene00006465"}, {"annotation": {"kegg.genes": "CELE_F08C6.6", "wormbase": "WBGene00017244", "sbo": "SBO:0000243", "uniprot": "Q19202"}, "name": "apy-1", "id": "WBGene00017244"}, {"annotation": {"kegg.genes": "CELE_T21C9.6", "wormbase": "WBGene00011893", "sbo": "SBO:0000243", "uniprot": "Q22649"}, "name": "T21C9.6", "id": "WBGene00011893"}, {"annotation": {"kegg.genes": "CELE_D1005.1", "wormbase": "WBGene00016995", "sbo": "SBO:0000243", "uniprot": "P53585"}, "name": "acly-1", "id": "WBGene00016995"}, {"annotation": {"kegg.genes": "CELE_B0365.1", "wormbase": "WBGene00007150", "sbo": "SBO:0000243", "uniprot": "P90731"}, "name": "acly-2", "id": "WBGene00007150"}, {"annotation": {"kegg.genes": "CELE_F58F12.1", "wormbase": "WBGene00019061", "sbo": "SBO:0000243", "uniprot": "Q09544"}, "name": "F58F12.1", "id": "WBGene00019061"}, {"annotation": {"kegg.genes": "CELE_C28H8.11", "wormbase": "WBGene00016201", "sbo": "SBO:0000243", "uniprot": ["Q27GU8", "Q09474", "Q8I7L6"]}, "name": "tdo-2", "id": "WBGene00016201"}, {"annotation": {"kegg.genes": "CELE_R02D3.5", "wormbase": "WBGene00019823", "sbo": "SBO:0000243", "uniprot": "O44501"}, "name": "fnta-1", "id": "WBGene00019823"}, {"annotation": {"kegg.genes": "CELE_Y105C5B.2", "wormbase": "WBGene00001549", "sbo": "SBO:0000243", "uniprot": "Q9U317"}, "name": "gcy-25", "id": "WBGene00001549"}, {"annotation": {"kegg.genes": "CELE_C28D4.3", "wormbase": "WBGene00001607", "sbo": "SBO:0000243", "uniprot": "O02225"}, "name": "gln-6", "id": "WBGene00001607"}, {"annotation": {"kegg.genes": "CELE_F09E5.2", "wormbase": "WBGene00017282", "sbo": "SBO:0000243", "uniprot": "Q19265"}, "name": "algn-2", "id": "WBGene00017282"}, {"annotation": {"kegg.genes": "CELE_K08F8.4", "wormbase": "WBGene00000240", "sbo": "SBO:0000243", "uniprot": ["P90925", "I2HA98"]}, "name": "pah-1", "id": "WBGene00000240"}, {"annotation": {"kegg.genes": "CELE_T19H5.6", "wormbase": "WBGene00044807", "sbo": "SBO:0000243", "uniprot": "D3KFR9"}, "name": "T19H5.6", "id": "WBGene00044807"}, {"annotation": {"kegg.genes": "CELE_K09E4.2", "wormbase": "WBGene00010720", "sbo": "SBO:0000243", "uniprot": ["E5QCI4", "E5QCI3"]}, "name": "K09E4.2", "id": "WBGene00010720"}, {"annotation": {"kegg.genes": "CELE_T05H4.1", "wormbase": "WBGene00020264", "sbo": "SBO:0000243", "uniprot": "O16526"}, "name": "acl-8", "id": "WBGene00020264"}, {"annotation": {"kegg.genes": "CELE_ZK40.1", "wormbase": "WBGene00022646", "sbo": "SBO:0000243", "uniprot": "Q23087"}, "name": "acl-9", "id": "WBGene00022646"}, {"annotation": {"kegg.genes": "CELE_W01C9.4", "wormbase": "WBGene00012177", "sbo": "SBO:0000243", "uniprot": "Q23116"}, "name": "decr-1.2", "id": "WBGene00012177"}, {"annotation": {"kegg.genes": "CELE_T05C12.3", "wormbase": "WBGene00011467", "sbo": "SBO:0000243", "uniprot": "Q22230"}, "name": "decr-1.3", "id": "WBGene00011467"}, {"annotation": {"kegg.genes": "CELE_F49H12.6", "wormbase": "WBGene00018657", "sbo": "SBO:0000243", "uniprot": ["Q9N5S8", "Q9N5S9"]}, "name": "acl-4", "id": "WBGene00018657"}, {"annotation": {"kegg.genes": "CELE_R07E3.5", "wormbase": "WBGene00011106", "sbo": "SBO:0000243", "uniprot": ["Q21812", "Q1ZXU8"]}, "name": "acl-5", "id": "WBGene00011106"}, {"annotation": {"kegg.genes": "CELE_Y66H1B.4", "wormbase": "WBGene00004981", "sbo": "SBO:0000243", "uniprot": "Q9Y194"}, "name": "spl-1", "id": "WBGene00004981"}, {"annotation": {"kegg.genes": "CELE_C28D4.2", "wormbase": "WBGene00000509", "sbo": "SBO:0000243", "uniprot": ["B3GWD5", "O17610"]}, "name": "cka-1", "id": "WBGene00000509"}, {"annotation": {"kegg.genes": "CELE_C49G7.8", "wormbase": "WBGene00016786", "sbo": "SBO:0000243", "uniprot": "O16220"}, "name": "cyp-35A4", "id": "WBGene00016786"}, {"annotation": {"kegg.genes": "CELE_K07C6.5", "wormbase": "WBGene00019473", "sbo": "SBO:0000243", "uniprot": "O44649"}, "name": "cyp-35A5", "id": "WBGene00019473"}, {"annotation": {"kegg.genes": "CELE_C03G6.15", "wormbase": "WBGene00015400", "sbo": "SBO:0000243", "uniprot": "O02628"}, "name": "cyp-35A2", "id": "WBGene00015400"}, {"annotation": {"kegg.genes": "CELE_K07C5.5", "wormbase": "WBGene00010628", "sbo": "SBO:0000243", "uniprot": ["G1K0X1", "G5EDL5"]}, "name": "ceeh-2", "id": "WBGene00010628"}, {"annotation": {"kegg.genes": "CELE_C03G6.14", "wormbase": "WBGene00015399", "sbo": "SBO:0000243", "uniprot": "O02627"}, "name": "cyp-35A1", "id": "WBGene00015399"}, {"annotation": {"kegg.genes": "CELE_H28O16.1", "wormbase": "WBGene00010419", "sbo": "SBO:0000243", "uniprot": "Q9XXK1"}, "name": "H28O16.1", "id": "WBGene00010419"}, {"annotation": {"kegg.genes": "CELE_Y38F1A.6", "wormbase": "WBGene00012608", "sbo": "SBO:0000243", "uniprot": "Q9U2M4"}, "name": "hphd-1", "id": "WBGene00012608"}, {"annotation": {"kegg.genes": "CELE_T05G5.6", "wormbase": "WBGene00001155", "sbo": "SBO:0000243", "uniprot": "P34559"}, "name": "ech-6", "id": "WBGene00001155"}, {"annotation": {"kegg.genes": "CELE_F25H2.5", "wormbase": "WBGene00009119", "sbo": "SBO:0000243", "uniprot": "Q93576"}, "name": "ndk-1", "id": "WBGene00009119"}, {"annotation": {"kegg.genes": "CELE_C10F3.3", "wormbase": "WBGene00000069", "sbo": "SBO:0000243", "uniprot": "O16880"}, "name": "acy-2", "id": "WBGene00000069"}, {"annotation": {"kegg.genes": "CELE_Y53F4B.4", "wormbase": "WBGene00013151", "sbo": "SBO:0000243", "uniprot": ["Q9NAA8", "Q9NAA7"]}, "name": "nsun-5", "id": "WBGene00013151"}, {"annotation": {"kegg.genes": "CELE_Y110A7A.4", "wormbase": "WBGene00022455", "sbo": "SBO:0000243", "uniprot": "Q9N588"}, "name": "tyms-1", "id": "WBGene00022455"}, {"annotation": {"kegg.genes": "CELE_F36H1.5", "wormbase": "WBGene00009493", "sbo": "SBO:0000243", "uniprot": "Q20106"}, "name": "hrg-4", "id": "WBGene00009493"}, {"annotation": {"kegg.genes": "CELE_T20B5.3", "wormbase": "WBGene00020596", "sbo": "SBO:0000243", "uniprot": ["Q1WBU8", "A8WFI7"]}, "name": "oga-1", "id": "WBGene00020596"}, {"annotation": {"kegg.genes": "CELE_F17C8.1", "wormbase": "WBGene00000068", "sbo": "SBO:0000243", "uniprot": "Q19523"}, "name": "acy-1", "id": "WBGene00000068"}, {"annotation": {"kegg.genes": "CELE_Y37B11A.3", "wormbase": "WBGene00021345", "sbo": "SBO:0000243", "uniprot": "Q9BKQ2"}, "name": "Y37B11A.3", "id": "WBGene00021345"}, {"annotation": {"kegg.genes": "CELE_Y37B11A.2", "wormbase": "WBGene00021344", "sbo": "SBO:0000243", "uniprot": "Q9BKQ3"}, "name": "Y37B11A.2", "id": "WBGene00021344"}, {"annotation": {"kegg.genes": "CELE_F47C10.6", "wormbase": "WBGene00018543", "sbo": "SBO:0000243", "uniprot": "O01558"}, "name": "ugt-32", "id": "WBGene00018543"}, {"annotation": {"kegg.genes": "CELE_Y46G5A.21", "wormbase": "WBGene00012911", "sbo": "SBO:0000243", "uniprot": "G5EFP8"}, "name": "acl-7", "id": "WBGene00012911"}, {"annotation": {"kegg.genes": "CELE_C05C10.3", "wormbase": "WBGene00007330", "sbo": "SBO:0000243", "uniprot": "Q09450"}, "name": "C05C10.3", "id": "WBGene00007330"}, {"annotation": {"kegg.genes": "CELE_C27D8.4", "wormbase": "WBGene00007780", "sbo": "SBO:0000243", "uniprot": "Q93291"}, "name": "C27D8.4", "id": "WBGene00007780"}, {"annotation": {"kegg.genes": "CELE_C10G11.5", "wormbase": "WBGene00004068", "sbo": "SBO:0000243", "uniprot": ["H2KYP8", "Q86NC9", "H2KYP7"]}, "name": "pnk-1", "id": "WBGene00004068"}, {"annotation": {"kegg.genes": "CELE_T24C4.1", "wormbase": "WBGene00020757", "sbo": "SBO:0000243", "uniprot": "Q9TZ33"}, "name": "ucr-2.3", "id": "WBGene00020757"}, {"annotation": {"kegg.genes": "CELE_F39G3.1", "wormbase": "WBGene00018206", "sbo": "SBO:0000243", "uniprot": "O16276"}, "name": "ugt-61", "id": "WBGene00018206"}, {"annotation": {"kegg.genes": "CELE_Y44E3A.2", "wormbase": "WBGene00000036", "sbo": "SBO:0000243", "uniprot": "G5EDV9"}, "name": "ace-2", "id": "WBGene00000036"}, {"annotation": {"kegg.genes": "CELE_W09B12.1", "wormbase": "WBGene00000035", "sbo": "SBO:0000243", "uniprot": "P38433"}, "name": "ace-1", "id": "WBGene00000035"}, {"annotation": {"kegg.genes": "CELE_F13E6.5", "wormbase": "WBGene00008749", "sbo": "SBO:0000243", "uniprot": "Q19403"}, "name": "F13E6.5", "id": "WBGene00008749"}, {"annotation": {"kegg.genes": "CELE_C07G3.9", "wormbase": "WBGene00015577", "sbo": "SBO:0000243", "uniprot": "O16322"}, "name": "ugt-64", "id": "WBGene00015577"}, {"annotation": {"kegg.genes": "CELE_F59B2.3", "wormbase": "WBGene00010308", "sbo": "SBO:0000243", "uniprot": "P34480"}, "name": "F59B2.3", "id": "WBGene00010308"}, {"annotation": {"kegg.genes": "CELE_Y77E11A.6", "wormbase": "WBGene00022309", "sbo": "SBO:0000243", "uniprot": "Q9N4B7"}, "name": "rpc-11", "id": "WBGene00022309"}, {"annotation": {"kegg.genes": "CELE_Y48B6A.7", "wormbase": "WBGene00000038", "sbo": "SBO:0000243", "uniprot": "G5EDN1"}, "name": "ace-4", "id": "WBGene00000038"}, {"annotation": {"kegg.genes": "CELE_W09H1.5", "wormbase": "WBGene00012375", "sbo": "SBO:0000243", "uniprot": "O45903"}, "name": "mecr-1", "id": "WBGene00012375"}, {"annotation": {"kegg.genes": "CELE_F41E6.5", "wormbase": "WBGene00018286", "sbo": "SBO:0000243", "uniprot": ["O16457", "B1GRK5"]}, "name": "F41E6.5", "id": "WBGene00018286"}, {"annotation": {"kegg.genes": "CELE_C55F2.1", "wormbase": "WBGene00016957", "sbo": "SBO:0000243", "uniprot": "Q95QQ4"}, "name": "atic-1", "id": "WBGene00016957"}, {"annotation": {"kegg.genes": "CELE_C03E10.4", "wormbase": "WBGene00001645", "sbo": "SBO:0000243", "uniprot": "O17560"}, "name": "gly-20", "id": "WBGene00001645"}, {"annotation": {"kegg.genes": "CELE_F14E5.4", "wormbase": "WBGene00008802", "sbo": "SBO:0000243", "uniprot": "Q19461"}, "name": "acp-2", "id": "WBGene00008802"}, {"annotation": {"kegg.genes": "CELE_F14E5.3", "wormbase": "WBGene00008801", "sbo": "SBO:0000243", "uniprot": "Q19460"}, "name": "acp-3", "id": "WBGene00008801"}, {"annotation": {"kegg.genes": "CELE_K02B2.1", "wormbase": "WBGene00019295", "sbo": "SBO:0000243", "uniprot": "Q21122"}, "name": "pfkb-1.2", "id": "WBGene00019295"}, {"annotation": {"kegg.genes": "CELE_T20D3.8", "wormbase": "WBGene00011860", "sbo": "SBO:0000243", "uniprot": "O01259"}, "name": "T20D3.8", "id": "WBGene00011860"}, {"annotation": {"kegg.genes": "CELE_Y73B6BL.25", "wormbase": "WBGene00022246", "sbo": "SBO:0000243", "uniprot": "Q9GUF1"}, "name": "acp-7", "id": "WBGene00022246"}, {"annotation": {"kegg.genes": "CELE_Y60A3A.14", "wormbase": "WBGene00013362", "sbo": "SBO:0000243", "uniprot": "Q9U1Z2"}, "name": "algn-7", "id": "WBGene00013362"}, {"annotation": {"kegg.genes": "CELE_F52E4.1", "wormbase": "WBGene00018701", "sbo": "SBO:0000243", "uniprot": ["Q8WQF1", "Q20676"]}, "name": "pccb-1", "id": "WBGene00018701"}, {"annotation": {"kegg.genes": "CELE_B0250.5", "wormbase": "WBGene00007122", "sbo": "SBO:0000243", "uniprot": "Q9XTI0"}, "name": "B0250.5", "id": "WBGene00007122"}, {"annotation": {"kegg.genes": "CELE_T05G5.5", "wormbase": "WBGene00011500", "sbo": "SBO:0000243", "uniprot": ["E5QCF8", "E5QCF6", "E5QCF7", "P34558"]}, "name": "T05G5.5", "id": "WBGene00011500"}, {"annotation": {"kegg.genes": "CELE_F26E4.9", "wormbase": "WBGene00000371", "sbo": "SBO:0000243", "uniprot": "P90849"}, "name": "cco-1", "id": "WBGene00000371"}, {"annotation": {"kegg.genes": "CELE_D2030.4", "wormbase": "WBGene00008414", "sbo": "SBO:0000243", "uniprot": "P90789"}, "name": "D2030.4", "id": "WBGene00008414"}, {"annotation": {"kegg.genes": "CELE_K08C7.5", "wormbase": "WBGene00001477", "sbo": "SBO:0000243", "uniprot": "G5EBJ9"}, "name": "fmo-2", "id": "WBGene00001477"}, {"annotation": {"kegg.genes": "CELE_T05H4.5", "wormbase": "WBGene00020268", "sbo": "SBO:0000243", "uniprot": "O16521"}, "name": "hpo-19", "id": "WBGene00020268"}, {"annotation": {"kegg.genes": "CELE_C54G10.4", "wormbase": "WBGene00008320", "sbo": "SBO:0000243", "uniprot": ["Q18844", "Q8I4M0"]}, "name": "slc-25A29", "id": "WBGene00008320"}, {"annotation": {"kegg.genes": "CELE_B0513.5", "wormbase": "WBGene00007197", "sbo": "SBO:0000243", "uniprot": "O45228"}, "name": "B0513.5", "id": "WBGene00007197"}, {"annotation": {"kegg.genes": "CELE_C49F5.5", "wormbase": "WBGene00008209", "sbo": "SBO:0000243", "uniprot": "O17681"}, "name": "C49F5.5", "id": "WBGene00008209"}, {"annotation": {"kegg.genes": "CELE_C08H9.13", "wormbase": "WBGene00007472", "sbo": "SBO:0000243", "uniprot": "Q17839"}, "name": "chil-7", "id": "WBGene00007472"}, {"annotation": {"kegg.genes": "CELE_C08H9.12", "wormbase": "WBGene00007471", "sbo": "SBO:0000243", "uniprot": "Q17836"}, "name": "chil-6", "id": "WBGene00007471"}, {"annotation": {"kegg.genes": "CELE_C08H9.11", "wormbase": "WBGene00007470", "sbo": "SBO:0000243", "uniprot": "Q17835"}, "name": "chil-5", "id": "WBGene00007470"}, {"annotation": {"kegg.genes": "CELE_C08H9.10", "wormbase": "WBGene00007469", "sbo": "SBO:0000243", "uniprot": "Q17834"}, "name": "chil-4", "id": "WBGene00007469"}, {"annotation": {"kegg.genes": "CELE_C08H9.7", "wormbase": "WBGene00007467", "sbo": "SBO:0000243", "uniprot": "Q17837"}, "name": "chil-3", "id": "WBGene00007467"}, {"annotation": {"kegg.genes": "CELE_C08H9.6", "wormbase": "WBGene00007466", "sbo": "SBO:0000243", "uniprot": "Q17841"}, "name": "chil-2", "id": "WBGene00007466"}, {"annotation": {"kegg.genes": "CELE_C08H9.4", "wormbase": "WBGene00007465", "sbo": "SBO:0000243", "uniprot": ["Q17838", "Q14V32"]}, "name": "chil-1", "id": "WBGene00007465"}, {"annotation": {"kegg.genes": "CELE_Y41E3.4", "wormbase": "WBGene00001336", "sbo": "SBO:0000243", "uniprot": ["D3YT95", "O62431", "D3YT96"]}, "name": "qars-1", "id": "WBGene00001336"}, {"annotation": {"kegg.genes": "CELE_H23N18.4", "wormbase": "WBGene00019235", "sbo": "SBO:0000243", "uniprot": "Q9TXZ3"}, "name": "H23N18.4", "id": "WBGene00019235"}, {"annotation": {"kegg.genes": "CELE_W02D3.2", "wormbase": "WBGene00020932", "sbo": "SBO:0000243", "uniprot": "O01815"}, "name": "dhod-1", "id": "WBGene00020932"}, {"annotation": {"kegg.genes": "CELE_T08B1.6", "wormbase": "WBGene00020343", "sbo": "SBO:0000243", "uniprot": "O44560"}, "name": "acs-3", "id": "WBGene00020343"}, {"annotation": {"kegg.genes": "CELE_F28F8.2", "wormbase": "WBGene00009221", "sbo": "SBO:0000243", "uniprot": "O18693"}, "name": "acs-2", "id": "WBGene00009221"}, {"annotation": {"kegg.genes": "CELE_F21D5.1", "wormbase": "WBGene00009006", "sbo": "SBO:0000243", "uniprot": "Q19680"}, "name": "F21D5.1", "id": "WBGene00009006"}, {"annotation": {"kegg.genes": "CELE_F37C12.7", "wormbase": "WBGene00018152", "sbo": "SBO:0000243", "uniprot": "Q20121"}, "name": "acs-4", "id": "WBGene00018152"}, {"annotation": {"kegg.genes": "CELE_ZK938.6", "wormbase": "WBGene00014162", "sbo": "SBO:0000243", "uniprot": "Q23675"}, "name": "chil-9", "id": "WBGene00014162"}, {"annotation": {"kegg.genes": "CELE_C08H9.14", "wormbase": "WBGene00007473", "sbo": "SBO:0000243", "uniprot": "Q17840"}, "name": "chil-8", "id": "WBGene00007473"}, {"annotation": {"kegg.genes": "CELE_F01G10.3", "wormbase": "WBGene00001158", "sbo": "SBO:0000243", "uniprot": "O17762"}, "name": "ech-9", "id": "WBGene00001158"}, {"annotation": {"kegg.genes": "CELE_F39B1.1", "wormbase": "WBGene00009552", "sbo": "SBO:0000243", "uniprot": "G5EDY0"}, "name": "piki-1", "id": "WBGene00009552"}, {"annotation": {"kegg.genes": "CELE_T20B3.1", "wormbase": "WBGene00011850", "sbo": "SBO:0000243", "uniprot": "Q9XUN8"}, "name": "T20B3.1", "id": "WBGene00011850"}, {"annotation": {"kegg.genes": "CELE_Y69A2AR.5", "wormbase": "WBGene00022076", "sbo": "SBO:0000243", "uniprot": "Q95XG9"}, "name": "daao-1", "id": "WBGene00022076"}, {"annotation": {"kegg.genes": "CELE_F53F10.2", "wormbase": "WBGene00018764", "sbo": "SBO:0000243", "uniprot": ["O01579", "H2KZ59"]}, "name": "F53F10.2", "id": "WBGene00018764"}, {"annotation": {"kegg.genes": "CELE_F28D1.9", "wormbase": "WBGene00009218", "sbo": "SBO:0000243", "uniprot": "Q19878"}, "name": "acs-20", "id": "WBGene00009218"}, {"annotation": {"kegg.genes": "CELE_K04A8.10", "wormbase": "WBGene00019379", "sbo": "SBO:0000243", "uniprot": "Q94260"}, "name": "K04A8.10", "id": "WBGene00019379"}, {"annotation": {"kegg.genes": "CELE_D1009.1", "wormbase": "WBGene00017012", "sbo": "SBO:0000243", "uniprot": ["Q18916", "Q95QP9"]}, "name": "acs-22", "id": "WBGene00017012"}, {"annotation": {"kegg.genes": "CELE_F37C12.3", "wormbase": "WBGene00018151", "sbo": "SBO:0000243", "uniprot": "Q20122"}, "name": "F37C12.3", "id": "WBGene00018151"}, {"annotation": {"wormbase": "WBGene00020366", "sbo": "SBO:0000243", "uniprot": "Q22347"}, "name": "acdh-10", "id": "WBGene00020366"}, {"annotation": {"kegg.genes": "CELE_E04F6.5", "wormbase": "WBGene00017125", "sbo": "SBO:0000243", "uniprot": ["Q6AHQ5", "Q19057"]}, "name": "acdh-12", "id": "WBGene00017125"}, {"annotation": {"kegg.genes": "ND2", "wormbase": "WBGene00010961", "sbo": "SBO:0000243", "uniprot": ["P24889", "G4XR29"]}, "name": "nduo-2", "id": "WBGene00010961"}, {"annotation": {"kegg.genes": "CELE_W09B6.1", "wormbase": "WBGene00004076", "sbo": "SBO:0000243", "uniprot": ["Q9GZI3", "H2L0M0", "Q7KQ29"]}, "name": "pod-2", "id": "WBGene00004076"}, {"annotation": {"kegg.genes": "CELE_F44C4.5", "wormbase": "WBGene00004092", "sbo": "SBO:0000243", "uniprot": "Q20390"}, "name": "ppt-1", "id": "WBGene00004092"}, {"annotation": {"kegg.genes": "CELE_T14G10.1", "wormbase": "WBGene00004091", "sbo": "SBO:0000243", "uniprot": "Q22501"}, "name": "pps-1", "id": "WBGene00004091"}, {"annotation": {"kegg.genes": "CELE_F27D9.5", "wormbase": "WBGene00017864", "sbo": "SBO:0000243", "uniprot": "Q19842"}, "name": "pcca-1", "id": "WBGene00017864"}, {"annotation": {"kegg.genes": "CELE_F53F1.3", "wormbase": "WBGene00009981", "sbo": "SBO:0000243", "uniprot": "P91998"}, "name": "F53F1.3", "id": "WBGene00009981"}, {"annotation": {"kegg.genes": "CELE_T26E3.7", "wormbase": "WBGene00012040", "sbo": "SBO:0000243", "uniprot": "O45827"}, "name": "T26E3.7", "id": "WBGene00012040"}, {"annotation": {"kegg.genes": "CELE_Y43F8B.19", "wormbase": "WBGene00077688", "sbo": "SBO:0000243", "uniprot": "B1V8J1"}, "name": "Y43F8B.19", "id": "WBGene00077688"}, {"annotation": {"kegg.genes": "CELE_F55A12.3", "wormbase": "WBGene00004087", "sbo": "SBO:0000243", "uniprot": "O01759"}, "name": "ppk-1", "id": "WBGene00004087"}, {"annotation": {"kegg.genes": "CELE_R09D1.2", "wormbase": "WBGene00011158", "sbo": "SBO:0000243", "uniprot": "Q21858"}, "name": "chil-16", "id": "WBGene00011158"}, {"annotation": {"kegg.genes": "CELE_VF11C1L.1", "wormbase": "WBGene00004089", "sbo": "SBO:0000243", "uniprot": "G5ED98"}, "name": "ppk-3", "id": "WBGene00004089"}, {"annotation": {"kegg.genes": "CELE_F59G1.1", "wormbase": "WBGene00019127", "sbo": "SBO:0000243", "uniprot": "Q21054"}, "name": "cgt-3", "id": "WBGene00019127"}, {"annotation": {"kegg.genes": "CELE_M176.8", "wormbase": "WBGene00010945", "sbo": "SBO:0000243", "uniprot": "D6R8W8"}, "name": "chil-13", "id": "WBGene00010945"}, {"annotation": {"kegg.genes": "CELE_M01B2.6", "wormbase": "WBGene00010799", "sbo": "SBO:0000243", "uniprot": "Q9XU76"}, "name": "chil-12", "id": "WBGene00010799"}, {"annotation": {"kegg.genes": "CELE_Y106G6E.4", "wormbase": "WBGene00013708", "sbo": "SBO:0000243", "uniprot": "Q9XWE6"}, "name": "Y106G6E.4", "id": "WBGene00013708"}, {"annotation": {"kegg.genes": "CELE_R102.4", "wormbase": "WBGene00011291", "sbo": "SBO:0000243", "uniprot": ["C6KRK8", "C6KRK9", "Q21890"]}, "name": "R102.4", "id": "WBGene00011291"}, {"annotation": {"kegg.genes": "CELE_M03A1.6", "wormbase": "WBGene00019747", "sbo": "SBO:0000243", "uniprot": ["Q8WQE0", "G8JYA8", "Q21478", "G5EEM9", "G4SGU1"]}, "name": "ipla-1", "id": "WBGene00019747"}, {"annotation": {"kegg.genes": "CELE_K03A1.5", "wormbase": "WBGene00006351", "sbo": "SBO:0000243", "uniprot": "Q21166"}, "name": "sur-5", "id": "WBGene00006351"}, {"annotation": {"kegg.genes": "CELE_R09D1.6", "wormbase": "WBGene00011162", "sbo": "SBO:0000243", "uniprot": "Q21862"}, "name": "chil-19", "id": "WBGene00011162"}, {"annotation": {"kegg.genes": "CELE_R09D1.5", "wormbase": "WBGene00011161", "sbo": "SBO:0000243", "uniprot": "Q21861"}, "name": "chil-18", "id": "WBGene00011161"}, {"annotation": {"kegg.genes": "CELE_ZK593.1", "wormbase": "WBGene00014001", "sbo": "SBO:0000243", "uniprot": ["D3YT37", "D3YT36", "Q23539"]}, "name": "pyk-2", "id": "WBGene00014001"}, {"annotation": {"kegg.genes": "CELE_C29E4.8", "wormbase": "WBGene00002879", "sbo": "SBO:0000243", "uniprot": "P34346"}, "name": "let-754", "id": "WBGene00002879"}, {"annotation": {"kegg.genes": "CELE_F54C8.1", "wormbase": "WBGene00010035", "sbo": "SBO:0000243", "uniprot": "P34439"}, "name": "F54C8.1", "id": "WBGene00010035"}, {"annotation": {"kegg.genes": "ND1", "wormbase": "WBGene00010959", "sbo": "SBO:0000243", "uniprot": "G4XR16"}, "name": "nduo-1", "id": "WBGene00010959"}, {"annotation": {"kegg.genes": "CELE_ZK1128.2", "wormbase": "WBGene00014228", "sbo": "SBO:0000243", "uniprot": "Q09357"}, "name": "mett-10", "id": "WBGene00014228"}, {"annotation": {"kegg.genes": "CELE_F07A11.2", "wormbase": "WBGene00008546", "sbo": "SBO:0000243", "uniprot": ["Q95QM8", "Q19130"]}, "name": "gfat-1", "id": "WBGene00008546"}, {"annotation": {"kegg.genes": "CELE_ZK863.3", "wormbase": "WBGene00014123", "sbo": "SBO:0000243", "uniprot": "Q23651"}, "name": "elpc-3", "id": "WBGene00014123"}, {"annotation": {"kegg.genes": "CELE_F58B3.5", "wormbase": "WBGene00003415", "sbo": "SBO:0000243", "uniprot": ["Q20970", "D3YT55", "D3YT56"]}, "name": "mars-1", "id": "WBGene00003415"}, {"annotation": {"kegg.genes": "CELE_C36B1.7", "wormbase": "WBGene00007974", "sbo": "SBO:0000243", "uniprot": "Q93341"}, "name": "dhfr-1", "id": "WBGene00007974"}, {"annotation": {"kegg.genes": "CELE_C37H5.8", "wormbase": "WBGene00002010", "sbo": "SBO:0000243", "uniprot": "P11141"}, "name": "hsp-6", "id": "WBGene00002010"}, {"annotation": {"kegg.genes": "CELE_T25B9.1", "wormbase": "WBGene00012007", "sbo": "SBO:0000243", "uniprot": "Q22768"}, "name": "T25B9.1", "id": "WBGene00012007"}, {"annotation": {"kegg.genes": "CELE_Y4C6B.6", "wormbase": "WBGene00021160", "sbo": "SBO:0000243", "uniprot": "Q9UB00"}, "name": "gba-4", "id": "WBGene00021160"}, {"annotation": {"kegg.genes": "CELE_T27E9.2", "wormbase": "WBGene00012094", "sbo": "SBO:0000243", "uniprot": "O45864"}, "name": "T27E9.2", "id": "WBGene00012094"}, {"annotation": {"kegg.genes": "CELE_C33C12.8", "wormbase": "WBGene00016340", "sbo": "SBO:0000243", "uniprot": "O16581"}, "name": "gba-2", "id": "WBGene00016340"}, {"annotation": {"kegg.genes": "CELE_F11E6.1", "wormbase": "WBGene00008706", "sbo": "SBO:0000243", "uniprot": "G5ECR8"}, "name": "gba-3", "id": "WBGene00008706"}, {"annotation": {"kegg.genes": "CELE_T20H4.5", "wormbase": "WBGene00020636", "sbo": "SBO:0000243", "uniprot": "Q22619"}, "name": "T20H4.5", "id": "WBGene00020636"}, {"annotation": {"kegg.genes": "CELE_Y47D7A.16", "wormbase": "WBGene00044637", "sbo": "SBO:0000243", "uniprot": "Q3LFN0"}, "name": "rft-1", "id": "WBGene00044637"}, {"annotation": {"kegg.genes": "CELE_Y73B6BL.29", "wormbase": "WBGene00022250", "sbo": "SBO:0000243", "uniprot": "Q95XD5"}, "name": "Y73B6BL.29", "id": "WBGene00022250"}, {"annotation": {"kegg.genes": "CELE_K06H7.9", "wormbase": "WBGene00019460", "sbo": "SBO:0000243", "uniprot": "G5EFQ1"}, "name": "idi-1", "id": "WBGene00019460"}, {"annotation": {"kegg.genes": "CELE_R07B5.9", "wormbase": "WBGene00045419", "sbo": "SBO:0000243", "uniprot": ["G5EGP0", "D7SFM3", "G5EGU3", "G5EBH5", "Q21789"]}, "name": "lsy-12", "id": "WBGene00045419"}, {"annotation": {"kegg.genes": "CELE_F22B3.4", "wormbase": "WBGene00009035", "sbo": "SBO:0000243", "uniprot": "Q19699"}, "name": "gfat-2", "id": "WBGene00009035"}, {"annotation": {"kegg.genes": "CELE_C05E4.9", "wormbase": "WBGene00001564", "sbo": "SBO:0000243", "uniprot": ["Q10663", "Q8IA71"]}, "name": "icl-1", "id": "WBGene00001564"}, {"annotation": {"kegg.genes": "CELE_K10D2.6", "wormbase": "WBGene00001262", "sbo": "SBO:0000243", "uniprot": "Q09590"}, "name": "emb-8", "id": "WBGene00001262"}, {"annotation": {"kegg.genes": "CELE_C33A12.7", "wormbase": "WBGene00007886", "sbo": "SBO:0000243", "uniprot": "O17636"}, "name": "ethe-1", "id": "WBGene00007886"}, {"annotation": {"kegg.genes": "CELE_ZK829.4", "wormbase": "WBGene00014095", "sbo": "SBO:0000243", "uniprot": "Q23621"}, "name": "gdh-1", "id": "WBGene00014095"}, {"annotation": {"kegg.genes": "CELE_F26H9.5", "wormbase": "WBGene00009177", "sbo": "SBO:0000243", "uniprot": "P91856"}, "name": "F26H9.5", "id": "WBGene00009177"}, {"annotation": {"kegg.genes": "CELE_F13H10.4", "wormbase": "WBGene00008775", "sbo": "SBO:0000243", "uniprot": ["A5JYS7", "Q19426"]}, "name": "mogs-1", "id": "WBGene00008775"}, {"annotation": {"kegg.genes": "CELE_W01A11.5", "wormbase": "WBGene00020911", "sbo": "SBO:0000243", "uniprot": "Q23066"}, "name": "cpt-6", "id": "WBGene00020911"}, {"annotation": {"kegg.genes": "CELE_Y46G5A.17", "wormbase": "WBGene00012907", "sbo": "SBO:0000243", "uniprot": "Q9U2F2"}, "name": "cpt-1", "id": "WBGene00012907"}, {"annotation": {"kegg.genes": "CELE_Y57G11C.47", "wormbase": "WBGene00013336", "sbo": "SBO:0000243", "uniprot": "Q7YTI0"}, "name": "pnc-2", "id": "WBGene00013336"}, {"annotation": {"kegg.genes": "CELE_Y38C1AA.3", "wormbase": "WBGene00021395", "sbo": "SBO:0000243", "uniprot": ["A7WK39", "Q9N426"]}, "name": "pnc-1", "id": "WBGene00021395"}, {"annotation": {"kegg.genes": "CELE_R07H5.2", "wormbase": "WBGene00011122", "sbo": "SBO:0000243", "uniprot": ["G5EFE6", "G5ECS9"]}, "name": "cpt-2", "id": "WBGene00011122"}, {"annotation": {"kegg.genes": "CELE_W02F12.5", "wormbase": "WBGene00020950", "sbo": "SBO:0000243", "uniprot": "O45148"}, "name": "dlst-1", "id": "WBGene00020950"}, {"annotation": {"kegg.genes": "CELE_R11A8.5", "wormbase": "WBGene00011239", "sbo": "SBO:0000243", "uniprot": "Q21925"}, "name": "pges-2", "id": "WBGene00011239"}, {"annotation": {"kegg.genes": "CELE_K08C7.2", "wormbase": "WBGene00001476", "sbo": "SBO:0000243", "uniprot": "G5EDP6"}, "name": "fmo-1", "id": "WBGene00001476"}, {"annotation": {"kegg.genes": "CELE_Y66D12A.23", "wormbase": "WBGene00013447", "sbo": "SBO:0000243", "uniprot": "Q95PZ8"}, "name": "nars-2", "id": "WBGene00013447"}, {"annotation": {"kegg.genes": "CELE_F22D6.3", "wormbase": "WBGene00003815", "sbo": "SBO:0000243", "uniprot": "Q19722"}, "name": "nars-1", "id": "WBGene00003815"}, {"annotation": {"kegg.genes": "CELE_ZC434.8", "wormbase": "WBGene00013894", "sbo": "SBO:0000243", "uniprot": "Q27535"}, "name": "ZC434.8", "id": "WBGene00013894"}, {"annotation": {"kegg.genes": "CELE_F44G4.2", "wormbase": "WBGene00009712", "sbo": "SBO:0000243", "uniprot": "Q20412"}, "name": "F44G4.2", "id": "WBGene00009712"}, {"annotation": {"kegg.genes": "CELE_Y47D3B.10", "wormbase": "WBGene00001077", "sbo": "SBO:0000243", "uniprot": "Q10576"}, "name": "dpy-18", "id": "WBGene00001077"}, {"annotation": {"kegg.genes": "CELE_C29H12.1", "wormbase": "WBGene00004680", "sbo": "SBO:0000243", "uniprot": "Q18316"}, "name": "rars-2", "id": "WBGene00004680"}, {"annotation": {"kegg.genes": "CELE_F26F4.10", "wormbase": "WBGene00004679", "sbo": "SBO:0000243", "uniprot": ["Q19825", "Q65ZK0", "A5HU89"]}, "name": "rars-1", "id": "WBGene00004679"}, {"annotation": {"kegg.genes": "CELE_C25A1.7", "wormbase": "WBGene00002153", "sbo": "SBO:0000243", "uniprot": ["E2JL04", "E2JL03"]}, "name": "iars-2", "id": "WBGene00002153"}, {"annotation": {"kegg.genes": "CELE_R11A8.6", "wormbase": "WBGene00002152", "sbo": "SBO:0000243", "uniprot": "Q21926"}, "name": "iars-1", "id": "WBGene00002152"}, {"annotation": {"kegg.genes": "CELE_AH6.1", "wormbase": "WBGene00001528", "sbo": "SBO:0000243", "uniprot": "Q09435"}, "name": "gcy-1", "id": "WBGene00001528"}, {"annotation": {"kegg.genes": "CELE_R134.1", "wormbase": "WBGene00001530", "sbo": "SBO:0000243", "uniprot": "Q10028"}, "name": "gcy-3", "id": "WBGene00001530"}, {"annotation": {"kegg.genes": "CELE_T01C2.1", "wormbase": "WBGene00000071", "sbo": "SBO:0000243", "uniprot": "Q966F9"}, "name": "acy-4", "id": "WBGene00000071"}, {"annotation": {"kegg.genes": "CELE_ZK970.6", "wormbase": "WBGene00001532", "sbo": "SBO:0000243", "uniprot": "Q23682"}, "name": "gcy-5", "id": "WBGene00001532"}, {"annotation": {"kegg.genes": "CELE_ZK970.5", "wormbase": "WBGene00001531", "sbo": "SBO:0000243", "uniprot": "Q23681"}, "name": "gcy-4", "id": "WBGene00001531"}, {"annotation": {"kegg.genes": "CELE_B0001.4", "wormbase": "WBGene00007089", "sbo": "SBO:0000243", "uniprot": "Q17413"}, "name": "B0001.4", "id": "WBGene00007089"}, {"annotation": {"kegg.genes": "CELE_ZK455.2", "wormbase": "WBGene00001536", "sbo": "SBO:0000243", "uniprot": "Q23496"}, "name": "gcy-9", "id": "WBGene00001536"}, {"annotation": {"kegg.genes": "CELE_C49H3.1", "wormbase": "WBGene00001535", "sbo": "SBO:0000243", "uniprot": "Q9GYQ4"}, "name": "gcy-8", "id": "WBGene00001535"}, {"annotation": {"kegg.genes": "CELE_T12A2.2", "wormbase": "WBGene00020437", "sbo": "SBO:0000243", "uniprot": "P46975"}, "name": "stt-3", "id": "WBGene00020437"}, {"annotation": {"kegg.genes": "CELE_Y48B6A.12", "wormbase": "WBGene00012983", "sbo": "SBO:0000243", "uniprot": "Q9U296"}, "name": "men-1", "id": "WBGene00012983"}, {"annotation": {"kegg.genes": "CELE_ZK563.7", "wormbase": "WBGene00044355", "sbo": "SBO:0000243", "uniprot": "Q4TTB1"}, "name": "ZK563.7", "id": "WBGene00044355"}, {"annotation": {"kegg.genes": "CELE_C39D10.3", "wormbase": "WBGene00016531", "sbo": "SBO:0000243", "uniprot": ["A4UVJ6", "Q18524"]}, "name": "C39D10.3", "id": "WBGene00016531"}, {"annotation": {"kegg.genes": "CELE_F49H6.5", "wormbase": "WBGene00009908", "sbo": "SBO:0000243", "uniprot": "Q9XV04"}, "name": "F49H6.5", "id": "WBGene00009908"}, {"annotation": {"kegg.genes": "CELE_C01B10.3", "wormbase": "WBGene00015278", "sbo": "SBO:0000243", "uniprot": "Q17543"}, "name": "C01B10.3", "id": "WBGene00015278"}, {"annotation": {"kegg.genes": "CELE_R11G1.3", "wormbase": "WBGene00001759", "sbo": "SBO:0000243", "uniprot": "Q21945"}, "name": "gst-11", "id": "WBGene00001759"}, {"annotation": {"kegg.genes": "CELE_K09A9.5", "wormbase": "WBGene00001520", "sbo": "SBO:0000243", "uniprot": "Q93873"}, "name": "gas-1", "id": "WBGene00001520"}, {"annotation": {"kegg.genes": "CELE_F10C2.6", "wormbase": "WBGene00001095", "sbo": "SBO:0000243", "uniprot": "P90831"}, "name": "dars-2", "id": "WBGene00001095"}, {"annotation": {"kegg.genes": "CELE_F58A4.9", "wormbase": "WBGene00010230", "sbo": "SBO:0000243", "uniprot": "P34476"}, "name": "rpac-19", "id": "WBGene00010230"}, {"annotation": {"kegg.genes": "CELE_T25G3.4", "wormbase": "WBGene00012031", "sbo": "SBO:0000243", "uniprot": "P90795"}, "name": "T25G3.4", "id": "WBGene00012031"}, {"annotation": {"kegg.genes": "CELE_F08B4.5", "wormbase": "WBGene00017237", "sbo": "SBO:0000243", "uniprot": "Q19196"}, "name": "pole-2", "id": "WBGene00017237"}, {"annotation": {"kegg.genes": "CELE_F33H2.5", "wormbase": "WBGene00009368", "sbo": "SBO:0000243", "uniprot": "O62218"}, "name": "pole-1", "id": "WBGene00009368"}, {"annotation": {"kegg.genes": "CELE_K04G2.5", "wormbase": "WBGene00010564", "sbo": "SBO:0000243", "uniprot": "Q21224"}, "name": "ath-1", "id": "WBGene00010564"}, {"annotation": {"kegg.genes": "CELE_Y56A3A.19", "wormbase": "WBGene00013237", "sbo": "SBO:0000243", "uniprot": "Q9U241"}, "name": "Y56A3A.19", "id": "WBGene00013237"}, {"annotation": {"kegg.genes": "CELE_ZK856.10", "wormbase": "WBGene00014111", "sbo": "SBO:0000243", "uniprot": "Q23645"}, "name": "rpc-25", "id": "WBGene00014111"}, {"annotation": {"kegg.genes": "CELE_M03C11.4", "wormbase": "WBGene00044069", "sbo": "SBO:0000243", "uniprot": "Q21484"}, "name": "hat-1", "id": "WBGene00044069"}, {"annotation": {"kegg.genes": "CELE_F19G12.2", "wormbase": "WBGene00017610", "sbo": "SBO:0000243", "uniprot": "Q19599"}, "name": "F19G12.2", "id": "WBGene00017610"}, {"annotation": {"kegg.genes": "CELE_Y94H6A.7", "wormbase": "WBGene00022379", "sbo": "SBO:0000243", "uniprot": "A7WK41"}, "name": "Y94H6A.7", "id": "WBGene00022379"}, {"annotation": {"kegg.genes": "CELE_F38E11.3", "wormbase": "WBGene00000775", "sbo": "SBO:0000243", "uniprot": "Q20166"}, "name": "cpin-1", "id": "WBGene00000775"}, {"annotation": {"kegg.genes": "CELE_C17C3.1", "wormbase": "WBGene00015887", "sbo": "SBO:0000243", "uniprot": ["H2KYT6", "H2KYT7", "H2KYT8", "Q9BIA9", "B0M0L9"]}, "name": "C17C3.1", "id": "WBGene00015887"}, {"annotation": {"kegg.genes": "CELE_K05B2.4", "wormbase": "WBGene00019404", "sbo": "SBO:0000243", "uniprot": "Q9GYN3"}, "name": "K05B2.4", "id": "WBGene00019404"}, {"annotation": {"kegg.genes": "CELE_Y97E10AL.2", "wormbase": "WBGene00022393", "sbo": "SBO:0000243", "uniprot": "Q965S2"}, "name": "abhd-12", "id": "WBGene00022393"}, {"annotation": {"kegg.genes": "CELE_R11E3.4", "wormbase": "WBGene00020006", "sbo": "SBO:0000243"}, "name": "set-15", "id": "WBGene00020006"}, {"annotation": {"kegg.genes": "CELE_T12D8.1", "wormbase": "WBGene00011729", "sbo": "SBO:0000243", "uniprot": "G5EGI1"}, "name": "set-16", "id": "WBGene00011729"}, {"annotation": {"kegg.genes": "CELE_R151.2", "wormbase": "WBGene00020107", "sbo": "SBO:0000243", "uniprot": ["Q6AHR3", "Q9BI73", "Q95QB6", "Q21994"]}, "name": "R151.2", "id": "WBGene00020107"}, {"annotation": {"kegg.genes": "CELE_F34D6.4", "wormbase": "WBGene00018023", "sbo": "SBO:0000243", "uniprot": "O17186"}, "name": "set-11", "id": "WBGene00018023"}, {"annotation": {"kegg.genes": "CELE_K09F5.5", "wormbase": "WBGene00019584", "sbo": "SBO:0000243", "uniprot": "Q21404"}, "name": "set-12", "id": "WBGene00019584"}, {"annotation": {"kegg.genes": "CELE_K12H6.11", "wormbase": "WBGene00019690", "sbo": "SBO:0000243", "uniprot": "Q9N5H6"}, "name": "set-13", "id": "WBGene00019690"}, {"annotation": {"kegg.genes": "CELE_T11G6.1", "wormbase": "WBGene00002001", "sbo": "SBO:0000243", "uniprot": "P34183"}, "name": "hars-1", "id": "WBGene00002001"}, {"annotation": {"kegg.genes": "COX2", "wormbase": "WBGene00010965", "sbo": "SBO:0000243", "uniprot": ["G5EGS6", "P24894"]}, "name": "ctc-2", "id": "WBGene00010965"}, {"annotation": {"kegg.genes": "CELE_F56G4.5", "wormbase": "WBGene00010160", "sbo": "SBO:0000243", "uniprot": "Q9TW67"}, "name": "png-1", "id": "WBGene00010160"}, {"annotation": {"kegg.genes": "CELE_B0491.7", "wormbase": "WBGene00007194", "sbo": "SBO:0000243", "uniprot": "Q17514"}, "name": "B0491.7", "id": "WBGene00007194"}, {"annotation": {"kegg.genes": "CELE_ZC373.1", "wormbase": "WBGene00013866", "sbo": "SBO:0000243", "uniprot": ["H9G2P9", "G5EFH8"]}, "name": "cbs-1", "id": "WBGene00013866"}, {"annotation": {"kegg.genes": "CELE_Y54G2A.17", "wormbase": "WBGene00021882", "sbo": "SBO:0000243", "uniprot": "Q95XX1"}, "name": "nprt-1", "id": "WBGene00021882"}, {"annotation": {"kegg.genes": "CELE_Y71D11A.3", "wormbase": "WBGene00022104", "sbo": "SBO:0000243", "uniprot": ["Q8T8B9", "Q95Y54"]}, "name": "acsd-1", "id": "WBGene00022104"}, {"annotation": {"kegg.genes": "CELE_R07E4.3", "wormbase": "WBGene00019937", "sbo": "SBO:0000243", "uniprot": "Q21817"}, "name": "R07E4.3", "id": "WBGene00019937"}, {"annotation": {"kegg.genes": "CELE_H13N06.6", "wormbase": "WBGene00006541", "sbo": "SBO:0000243", "uniprot": ["Q9XTQ6", "C6KRQ4"]}, "name": "tbh-1", "id": "WBGene00006541"}, {"annotation": {"kegg.genes": "CELE_T02G5.9", "wormbase": "WBGene00002238", "sbo": "SBO:0000243", "uniprot": ["Q2XN16", "Q95ZQ3", "Q22099"]}, "name": "kars-1", "id": "WBGene00002238"}, {"annotation": {"kegg.genes": "CELE_ZC155.4", "wormbase": "WBGene00022532", "sbo": "SBO:0000243", "uniprot": "Q23244"}, "name": "ZC155.4", "id": "WBGene00022532"}, {"annotation": {"kegg.genes": "CELE_ZK892.4", "wormbase": "WBGene00014128", "sbo": "SBO:0000243", "uniprot": "Q09618"}, "name": "ZK892.4", "id": "WBGene00014128"}, {"annotation": {"kegg.genes": "CELE_F35H12.4", "wormbase": "WBGene00018076", "sbo": "SBO:0000243", "uniprot": "Q20077"}, "name": "pifk-1", "id": "WBGene00018076"}, {"annotation": {"kegg.genes": "CELE_C02C6.1", "wormbase": "WBGene00001130", "sbo": "SBO:0000243", "uniprot": "P39055"}, "name": "dyn-1", "id": "WBGene00001130"}, {"annotation": {"kegg.genes": "CELE_C42C1.5", "wormbase": "WBGene00016583", "sbo": "SBO:0000243", "uniprot": "A3QMC8"}, "name": "tag-335", "id": "WBGene00016583"}, {"annotation": {"kegg.genes": "CELE_C34B7.2", "wormbase": "WBGene00007912", "sbo": "SBO:0000243", "uniprot": "P90770"}, "name": "C34B7.2", "id": "WBGene00007912"}, {"annotation": {"kegg.genes": "CELE_F46G10.3", "wormbase": "WBGene00004802", "sbo": "SBO:0000243", "uniprot": "Q20481"}, "name": "sir-2.3", "id": "WBGene00004802"}, {"annotation": {"kegg.genes": "CELE_T13C5.1", "wormbase": "WBGene00000905", "sbo": "SBO:0000243", "uniprot": "H2KYS3"}, "name": "daf-9", "id": "WBGene00000905"}, {"annotation": {"kegg.genes": "CELE_R11A8.4", "wormbase": "WBGene00004800", "sbo": "SBO:0000243", "uniprot": ["D3YT50", "Q21921"]}, "name": "sir-2.1", "id": "WBGene00004800"}, {"annotation": {"kegg.genes": "CELE_ZK1058.3", "wormbase": "WBGene00014203", "sbo": "SBO:0000243", "uniprot": "Q27536"}, "name": "ZK1058.3", "id": "WBGene00014203"}, {"annotation": {"kegg.genes": "CELE_C06A5.11", "wormbase": "WBGene00004803", "sbo": "SBO:0000243", "uniprot": "Q95Q89"}, "name": "sir-2.4", "id": "WBGene00004803"}, {"annotation": {"kegg.genes": "CELE_T20G5.2", "wormbase": "WBGene00000833", "sbo": "SBO:0000243", "uniprot": "P34575"}, "name": "cts-1", "id": "WBGene00000833"}, {"annotation": {"kegg.genes": "CELE_F02E9.7", "wormbase": "WBGene00008531", "sbo": "SBO:0000243", "uniprot": "O01320"}, "name": "F02E9.7", "id": "WBGene00008531"}, {"annotation": {"kegg.genes": "CELE_R08F11.1", "wormbase": "WBGene00019965", "sbo": "SBO:0000243", "uniprot": "O01893"}, "name": "R08F11.1", "id": "WBGene00019965"}, {"annotation": {"kegg.genes": "CELE_W01A8.4", "wormbase": "WBGene00012166", "sbo": "SBO:0000243", "uniprot": "Q23098"}, "name": "nuo-6", "id": "WBGene00012166"}, {"annotation": {"kegg.genes": "CELE_T22B11.5", "wormbase": "WBGene00020679", "sbo": "SBO:0000243", "uniprot": "O61199"}, "name": "ogdh-1", "id": "WBGene00020679"}, {"annotation": {"kegg.genes": "CELE_F43H9.2", "wormbase": "WBGene00018398", "sbo": "SBO:0000243", "uniprot": "Q20375"}, "name": "sptl-2", "id": "WBGene00018398"}, {"annotation": {"kegg.genes": "CELE_T22G5.5", "wormbase": "WBGene00011932", "sbo": "SBO:0000243", "uniprot": "Q9XVI6"}, "name": "sptl-3", "id": "WBGene00011932"}, {"annotation": {"kegg.genes": "CELE_F40F9.6", "wormbase": "WBGene00009583", "sbo": "SBO:0000243", "uniprot": ["Q20239", "Q9U3F8"]}, "name": "aagr-3", "id": "WBGene00009583"}, {"annotation": {"kegg.genes": "CELE_T21F4.1", "wormbase": "WBGene00020658", "sbo": "SBO:0000243", "uniprot": ["H2KZS0", "F5GU60"]}, "name": "T21F4.1", "id": "WBGene00020658"}, {"annotation": {"kegg.genes": "CELE_EEED8.8", "wormbase": "WBGene00003583", "sbo": "SBO:0000243", "uniprot": "Q09297"}, "name": "ndx-6", "id": "WBGene00003583"}, {"annotation": {"kegg.genes": "CELE_Y71F9B.9", "wormbase": "WBGene00022130", "sbo": "SBO:0000243", "uniprot": ["C0VXV5", "H2KZY2"]}, "name": "Y71F9B.9", "id": "WBGene00022130"}, {"annotation": {"kegg.genes": "CELE_F47B10.1", "wormbase": "WBGene00009812", "sbo": "SBO:0000243", "uniprot": "P53588"}, "name": "suca-1", "id": "WBGene00009812"}, {"annotation": {"kegg.genes": "CELE_W02G9.1", "wormbase": "WBGene00003579", "sbo": "SBO:0000243", "uniprot": "O61902"}, "name": "ndx-2", "id": "WBGene00003579"}, {"annotation": {"kegg.genes": "CELE_F53A2.7", "wormbase": "WBGene00009952", "sbo": "SBO:0000243", "uniprot": "O45552"}, "name": "acaa-2", "id": "WBGene00009952"}, {"annotation": {"kegg.genes": "CELE_C13B9.2", "wormbase": "WBGene00015733", "sbo": "SBO:0000243", "uniprot": "Q09235"}, "name": "C13B9.2", "id": "WBGene00015733"}, {"annotation": {"kegg.genes": "CELE_F56H6.5", "wormbase": "WBGene00010166", "sbo": "SBO:0000243", "uniprot": "O45583"}, "name": "gmd-2", "id": "WBGene00010166"}, {"annotation": {"kegg.genes": "CELE_H22K11.2", "wormbase": "WBGene00019225", "sbo": "SBO:0000243", "uniprot": "O76632"}, "name": "bgal-2", "id": "WBGene00019225"}, {"annotation": {"kegg.genes": "CELE_Y46G5A.24", "wormbase": "WBGene00012914", "sbo": "SBO:0000243", "uniprot": "Q9U2E4"}, "name": "bcmo-1", "id": "WBGene00012914"}, {"annotation": {"kegg.genes": "CELE_F53C3.12", "wormbase": "WBGene00018755", "sbo": "SBO:0000243", "uniprot": "Q9TXT9"}, "name": "bcmo-2", "id": "WBGene00018755"}, {"annotation": {"kegg.genes": "CELE_F35H8.6", "wormbase": "WBGene00009450", "sbo": "SBO:0000243", "uniprot": "Q20086"}, "name": "ugt-58", "id": "WBGene00009450"}, {"annotation": {"kegg.genes": "CELE_F25E2.3", "wormbase": "WBGene00017781", "sbo": "SBO:0000243", "uniprot": "Q19781"}, "name": "F25E2.3", "id": "WBGene00017781"}, {"annotation": {"kegg.genes": "CELE_F01D4.8", "wormbase": "WBGene00008490", "sbo": "SBO:0000243", "uniprot": "G5EF21"}, "name": "F01D4.8", "id": "WBGene00008490"}, {"annotation": {"kegg.genes": "CELE_ZC395.7", "wormbase": "WBGene00001823", "sbo": "SBO:0000243", "uniprot": "Q9GYG4"}, "name": "hap-1", "id": "WBGene00001823"}, {"annotation": {"kegg.genes": "CELE_C34F6.8", "wormbase": "WBGene00007942", "sbo": "SBO:0000243", "uniprot": "O17643"}, "name": "idh-2", "id": "WBGene00007942"}, {"annotation": {"kegg.genes": "CELE_F59B8.2", "wormbase": "WBGene00010317", "sbo": "SBO:0000243", "uniprot": ["H9G2T4", "Q21032", "H9G2T3"]}, "name": "idh-1", "id": "WBGene00010317"}, {"annotation": {"kegg.genes": "CELE_F58F9.7", "wormbase": "WBGene00019060", "sbo": "SBO:0000243", "uniprot": "Q20992"}, "name": "acox-3", "id": "WBGene00019060"}, {"annotation": {"kegg.genes": "CELE_W01A11.2", "wormbase": "WBGene00020910", "sbo": "SBO:0000243", "uniprot": "Q23067"}, "name": "dgtr-1", "id": "WBGene00020910"}, {"annotation": {"kegg.genes": "CELE_K02G10.6", "wormbase": "WBGene00002044", "sbo": "SBO:0000243", "uniprot": "Q7Z139"}, "name": "hyl-2", "id": "WBGene00002044"}, {"annotation": {"kegg.genes": "CELE_W07E11.1", "wormbase": "WBGene00012326", "sbo": "SBO:0000243", "uniprot": "G5EF05"}, "name": "W07E11.1", "id": "WBGene00012326"}, {"annotation": {"kegg.genes": "CELE_C56G3.2", "wormbase": "WBGene00016985", "sbo": "SBO:0000243", "uniprot": "Q18903"}, "name": "C56G3.2", "id": "WBGene00016985"}, {"annotation": {"kegg.genes": "CELE_C32F10.8", "wormbase": "WBGene00016333", "sbo": "SBO:0000243", "uniprot": ["Q86GU3", "O01685"]}, "name": "C32F10.8", "id": "WBGene00016333"}, {"annotation": {"kegg.genes": "CELE_T26A5.5", "wormbase": "WBGene00020821", "sbo": "SBO:0000243", "uniprot": "Q95Q98"}, "name": "jhdm-1", "id": "WBGene00020821"}, {"annotation": {"kegg.genes": "CELE_B0416.6", "wormbase": "WBGene00001638", "sbo": "SBO:0000243", "uniprot": "Q11068"}, "name": "gly-13", "id": "WBGene00001638"}, {"annotation": {"kegg.genes": "CELE_B0334.8", "wormbase": "WBGene00000090", "sbo": "SBO:0000243", "uniprot": "Q94125"}, "name": "age-1", "id": "WBGene00000090"}, {"annotation": {"kegg.genes": "CELE_F35G12.2", "wormbase": "WBGene00009440", "sbo": "SBO:0000243", "uniprot": "Q20049"}, "name": "idhg-1", "id": "WBGene00009440"}, {"annotation": {"kegg.genes": "CELE_T13B5.3", "wormbase": "WBGene00020471", "sbo": "SBO:0000243", "uniprot": "O17373"}, "name": "pho-14", "id": "WBGene00020471"}, {"annotation": {"kegg.genes": "CELE_W03B1.4", "wormbase": "WBGene00005662", "sbo": "SBO:0000243", "uniprot": "G5EF77"}, "name": "sars-2", "id": "WBGene00005662"}, {"annotation": {"kegg.genes": "CELE_C30F12.7", "wormbase": "WBGene00016266", "sbo": "SBO:0000243", "uniprot": "Q95YD8"}, "name": "idhg-2", "id": "WBGene00016266"}, {"annotation": {"kegg.genes": "CELE_C05C10.4", "wormbase": "WBGene00007331", "sbo": "SBO:0000243", "uniprot": "Q09451"}, "name": "pho-11", "id": "WBGene00007331"}, {"annotation": {"kegg.genes": "CELE_C05C10.1", "wormbase": "WBGene00007328", "sbo": "SBO:0000243", "uniprot": "Q09448"}, "name": "pho-10", "id": "WBGene00007328"}, {"annotation": {"kegg.genes": "CELE_C26E6.11", "wormbase": "WBGene00016144", "sbo": "SBO:0000243", "uniprot": "Q18218"}, "name": "mmab-1", "id": "WBGene00016144"}, {"annotation": {"kegg.genes": "CELE_C27A2.4", "wormbase": "WBGene00016152", "sbo": "SBO:0000243", "uniprot": "E7EM29"}, "name": "pho-12", "id": "WBGene00016152"}, {"annotation": {"kegg.genes": "CELE_Y19D10A.16", "wormbase": "WBGene00044734", "sbo": "SBO:0000243", "uniprot": "G5ECR6"}, "name": "Y19D10A.16", "id": "WBGene00044734"}, {"annotation": {"kegg.genes": "CELE_R01H10.7", "wormbase": "WBGene00010975", "sbo": "SBO:0000243", "uniprot": "Q21623"}, "name": "R01H10.7", "id": "WBGene00010975"}, {"annotation": {"kegg.genes": "CELE_Y37E3.3", "wormbase": "WBGene00021347", "sbo": "SBO:0000243", "uniprot": "Q9GR61"}, "name": "rpb-10", "id": "WBGene00021347"}, {"annotation": {"kegg.genes": "CELE_W01G7.3", "wormbase": "WBGene00012187", "sbo": "SBO:0000243", "uniprot": "Q9XVH6"}, "name": "rpb-11", "id": "WBGene00012187"}, {"annotation": {"kegg.genes": "CELE_F23B2.13", "wormbase": "WBGene00009078", "sbo": "SBO:0000243", "uniprot": "Q9U3I0"}, "name": "rpb-12", "id": "WBGene00009078"}, {"annotation": {"kegg.genes": "CELE_F53G12.3", "wormbase": "WBGene00018771", "sbo": "SBO:0000243", "uniprot": "O01795"}, "name": "duox-2", "id": "WBGene00018771"}, {"annotation": {"kegg.genes": "CELE_F55G7.2", "wormbase": "WBGene00010120", "sbo": "SBO:0000243", "uniprot": "Q20856"}, "name": "dot-1.4", "id": "WBGene00010120"}, {"annotation": {"kegg.genes": "CELE_ZC53.6", "wormbase": "WBGene00022512", "sbo": "SBO:0000243", "uniprot": "Q23375"}, "name": "dot-1.5", "id": "WBGene00022512"}, {"annotation": {"kegg.genes": "CELE_F54F7.7", "wormbase": "WBGene00010067", "sbo": "SBO:0000243", "uniprot": "Q20794"}, "name": "dot-1.2", "id": "WBGene00010067"}, {"annotation": {"kegg.genes": "CELE_W06D11.4", "wormbase": "WBGene00012302", "sbo": "SBO:0000243", "uniprot": "Q23200"}, "name": "dot-1.3", "id": "WBGene00012302"}, {"annotation": {"kegg.genes": "CELE_T14F9.3", "wormbase": "WBGene00020509", "sbo": "SBO:0000243", "uniprot": "Q22492"}, "name": "hex-1", "id": "WBGene00020509"}, {"annotation": {"kegg.genes": "CELE_Y39G10AR.18", "wormbase": "WBGene00021474", "sbo": "SBO:0000243", "uniprot": ["Q6AW06", "Q6AW05"]}, "name": "dot-1.1", "id": "WBGene00021474"}, {"annotation": {"kegg.genes": "CELE_ZK1005.1", "wormbase": "WBGene00004053", "sbo": "SBO:0000243", "uniprot": "Q9TXQ1"}, "name": "tank-1", "id": "WBGene00004053"}, {"annotation": {"kegg.genes": "CELE_T09B4.8", "wormbase": "WBGene00020382", "sbo": "SBO:0000243", "uniprot": "O02158"}, "name": "T09B4.8", "id": "WBGene00020382"}, {"annotation": {"kegg.genes": "CELE_ZC116.2", "wormbase": "WBGene00013854", "sbo": "SBO:0000243", "uniprot": "Q23240"}, "name": "cyc-2.2", "id": "WBGene00013854"}, {"annotation": {"kegg.genes": "CELE_D2024.2", "wormbase": "WBGene00017051", "sbo": "SBO:0000243", "uniprot": "Q18974"}, "name": "afmd-1", "id": "WBGene00017051"}, {"annotation": {"kegg.genes": "CELE_F01G4.5", "wormbase": "WBGene00008504", "sbo": "SBO:0000243", "uniprot": "Q93438"}, "name": "F01G4.5", "id": "WBGene00008504"}, {"annotation": {"kegg.genes": "CELE_ZC410.3", "wormbase": "WBGene00013881", "sbo": "SBO:0000243", "uniprot": ["D3YT22", "Q23296"]}, "name": "mans-4", "id": "WBGene00013881"}, {"annotation": {"kegg.genes": "CELE_F19B6.1", "wormbase": "WBGene00008948", "sbo": "SBO:0000243", "uniprot": ["H2L2A8", "Q9U3I7", "Q19583", "D3YT38"]}, "name": "F19B6.1", "id": "WBGene00008948"}, {"annotation": {"kegg.genes": "CELE_R08D7.7", "wormbase": "WBGene00011147", "sbo": "SBO:0000243", "uniprot": "P30646"}, "name": "R08D7.7", "id": "WBGene00011147"}, {"annotation": {"kegg.genes": "CELE_T07A9.2", "wormbase": "WBGene00001338", "sbo": "SBO:0000243", "uniprot": "O44413"}, "name": "ears-2", "id": "WBGene00001338"}, {"annotation": {"kegg.genes": "CELE_Y53F4B.2", "wormbase": "WBGene00001247", "sbo": "SBO:0000243", "uniprot": "Q9NAC6"}, "name": "elo-9", "id": "WBGene00001247"}, {"annotation": {"kegg.genes": "CELE_Y48G9A.8", "wormbase": "WBGene00004088", "sbo": "SBO:0000243", "uniprot": "Q9BL73"}, "name": "ppk-2", "id": "WBGene00004088"}, {"annotation": {"kegg.genes": "CELE_ZC434.5", "wormbase": "WBGene00001337", "sbo": "SBO:0000243", "uniprot": "Q23315"}, "name": "ears-1", "id": "WBGene00001337"}, {"annotation": {"kegg.genes": "CELE_C43E11.3", "wormbase": "WBGene00016603", "sbo": "SBO:0000243", "uniprot": ["A4LBC2", "A4LBC3"]}, "name": "met-1", "id": "WBGene00016603"}, {"annotation": {"kegg.genes": "CELE_R05D3.11", "wormbase": "WBGene00019883", "sbo": "SBO:0000243", "uniprot": "P34544"}, "name": "met-2", "id": "WBGene00019883"}, {"annotation": {"kegg.genes": "CELE_C09H5.2", "wormbase": "WBGene00015660", "sbo": "SBO:0000243", "uniprot": ["Q8IA86", "O16331"]}, "name": "catp-3", "id": "WBGene00015660"}, {"annotation": {"kegg.genes": "CELE_F22E10.5", "wormbase": "WBGene00009057", "sbo": "SBO:0000243", "uniprot": ["G5EC09", "G5EBS7"]}, "name": "cept-1", "id": "WBGene00009057"}, {"annotation": {"kegg.genes": "CELE_K04F10.4", "wormbase": "WBGene00000254", "sbo": "SBO:0000243", "uniprot": ["G8JYA5", "P51559"]}, "name": "bli-4", "id": "WBGene00000254"}, {"annotation": {"kegg.genes": "CELE_F11E6.5", "wormbase": "WBGene00001240", "sbo": "SBO:0000243", "uniprot": "Q9XVQ9"}, "name": "elo-2", "id": "WBGene00001240"}, {"annotation": {"kegg.genes": "CELE_D2024.3", "wormbase": "WBGene00001241", "sbo": "SBO:0000243", "uniprot": "P49191"}, "name": "elo-3", "id": "WBGene00001241"}, {"annotation": {"kegg.genes": "CELE_C40H1.4", "wormbase": "WBGene00001242", "sbo": "SBO:0000243", "uniprot": "Q03574"}, "name": "elo-4", "id": "WBGene00001242"}, {"annotation": {"kegg.genes": "CELE_F41H10.7", "wormbase": "WBGene00001243", "sbo": "SBO:0000243", "uniprot": "Q20300"}, "name": "elo-5", "id": "WBGene00001243"}, {"annotation": {"kegg.genes": "CELE_F56C11.1", "wormbase": "WBGene00000253", "sbo": "SBO:0000243", "uniprot": "O61213"}, "name": "bli-3", "id": "WBGene00000253"}, {"annotation": {"kegg.genes": "CELE_F56H11.3", "wormbase": "WBGene00001245", "sbo": "SBO:0000243", "uniprot": ["Q20904", "D3KFU0"]}, "name": "elo-7", "id": "WBGene00001245"}, {"annotation": {"kegg.genes": "CELE_R11D1.11", "wormbase": "WBGene00000984", "sbo": "SBO:0000243", "uniprot": "Q21929"}, "name": "dhs-21", "id": "WBGene00000984"}, {"annotation": {"kegg.genes": "CELE_ZK54.2", "wormbase": "WBGene00006602", "sbo": "SBO:0000243", "uniprot": "Q7YZT6"}, "name": "tps-1", "id": "WBGene00006602"}, {"annotation": {"kegg.genes": "CELE_F09E10.3", "wormbase": "WBGene00000988", "sbo": "SBO:0000243", "uniprot": "Q19246"}, "name": "dhs-25", "id": "WBGene00000988"}, {"annotation": {"kegg.genes": "CELE_M03A8.1", "wormbase": "WBGene00000991", "sbo": "SBO:0000243", "uniprot": "Q21481"}, "name": "dhs-28", "id": "WBGene00000991"}, {"annotation": {"kegg.genes": "CELE_F47G4.7", "wormbase": "WBGene00004875", "sbo": "SBO:0000243", "uniprot": "O02655"}, "name": "smd-1", "id": "WBGene00004875"}, {"annotation": {"kegg.genes": "CELE_C01G10.9", "wormbase": "WBGene00007236", "sbo": "SBO:0000243", "uniprot": "Q93169"}, "name": "C01G10.9", "id": "WBGene00007236"}, {"annotation": {"kegg.genes": "CELE_F46E10.10", "wormbase": "WBGene00018491", "sbo": "SBO:0000243", "uniprot": ["Q9UAV5", "Q8IA49", "Q8IA50"]}, "name": "mdh-1", "id": "WBGene00018491"}, {"annotation": {"kegg.genes": "CELE_B0041.6", "wormbase": "WBGene00015010", "sbo": "SBO:0000243", "uniprot": "O02058"}, "name": "ptps-1", "id": "WBGene00015010"}, {"annotation": {"kegg.genes": "CELE_F57F5.2", "wormbase": "WBGene00001553", "sbo": "SBO:0000243", "uniprot": ["G5EGJ1", "P90895", "H2L2D1"]}, "name": "gcy-33", "id": "WBGene00001553"}, {"annotation": {"kegg.genes": "CELE_C06B3.8", "wormbase": "WBGene00001552", "sbo": "SBO:0000243", "uniprot": "Q6DNF7"}, "name": "gcy-32", "id": "WBGene00001552"}, {"annotation": {"kegg.genes": "CELE_T07D1.1", "wormbase": "WBGene00001551", "sbo": "SBO:0000243", "uniprot": "Q86C56"}, "name": "gcy-31", "id": "WBGene00001551"}, {"annotation": {"kegg.genes": "CELE_F22B8.6", "wormbase": "WBGene00009048", "sbo": "SBO:0000243", "uniprot": "O45391"}, "name": "cth-1", "id": "WBGene00009048"}, {"annotation": {"kegg.genes": "CELE_C46E1.2", "wormbase": "WBGene00001556", "sbo": "SBO:0000243", "uniprot": "Q6DNF4"}, "name": "gcy-36", "id": "WBGene00001556"}, {"annotation": {"kegg.genes": "CELE_T04D3.4", "wormbase": "WBGene00001555", "sbo": "SBO:0000243", "uniprot": ["H2L2G5", "H2L2G4", "O02298"]}, "name": "gcy-35", "id": "WBGene00001555"}, {"annotation": {"kegg.genes": "CELE_M04G12.3", "wormbase": "WBGene00001554", "sbo": "SBO:0000243", "uniprot": "P92006"}, "name": "gcy-34", "id": "WBGene00001554"}, {"annotation": {"kegg.genes": "CELE_K11D12.4", "wormbase": "WBGene00019644", "sbo": "SBO:0000243", "uniprot": "O44619"}, "name": "cpt-4", "id": "WBGene00019644"}, {"annotation": {"kegg.genes": "CELE_F52D1.1", "wormbase": "WBGene00018682", "sbo": "SBO:0000243", "uniprot": "O17352"}, "name": "aagr-4", "id": "WBGene00018682"}, {"annotation": {"kegg.genes": "CELE_H37A05.1", "wormbase": "WBGene00010425", "sbo": "SBO:0000243", "uniprot": "Q9XXT5"}, "name": "lpin-1", "id": "WBGene00010425"}, {"annotation": {"kegg.genes": "CELE_Y71F9AL.5", "wormbase": "WBGene00001791", "sbo": "SBO:0000243", "uniprot": "Q9N4H6"}, "name": "gst-43", "id": "WBGene00001791"}, {"annotation": {"kegg.genes": "CELE_D1053.1", "wormbase": "WBGene00001790", "sbo": "SBO:0000243", "uniprot": "Q18938"}, "name": "gst-42", "id": "WBGene00001790"}, {"annotation": {"kegg.genes": "CELE_F36A4.7", "wormbase": "WBGene00000123", "sbo": "SBO:0000243", "uniprot": "P16356"}, "name": "ama-1", "id": "WBGene00000123"}, {"annotation": {"kegg.genes": "CELE_H21P03.3", "wormbase": "WBGene00004892", "sbo": "SBO:0000243", "uniprot": ["Q9U3D4", "H2L2K5"]}, "name": "sms-1", "id": "WBGene00004892"}, {"annotation": {"kegg.genes": "CELE_K02D7.1", "wormbase": "WBGene00019298", "sbo": "SBO:0000243", "uniprot": "O61217"}, "name": "K02D7.1", "id": "WBGene00019298"}, {"annotation": {"kegg.genes": "CELE_Y22D7AL.8", "wormbase": "WBGene00004894", "sbo": "SBO:0000243", "uniprot": "Q965Q4"}, "name": "sms-3", "id": "WBGene00004894"}, {"annotation": {"kegg.genes": "CELE_F53H8.4", "wormbase": "WBGene00004893", "sbo": "SBO:0000243", "uniprot": "Q20735"}, "name": "sms-2", "id": "WBGene00004893"}, {"annotation": {"kegg.genes": "CELE_T08H10.1", "wormbase": "WBGene00020369", "sbo": "SBO:0000243", "uniprot": "Q22352"}, "name": "T08H10.1", "id": "WBGene00020369"}, {"annotation": {"kegg.genes": "CELE_W05G11.6", "wormbase": "WBGene00021043", "sbo": "SBO:0000243", "uniprot": ["Q8ITY1", "Q8ITY0", "Q8ITY2", "O44906"]}, "name": "pck-1", "id": "WBGene00021043"}, {"annotation": {"kegg.genes": "CELE_F46G10.7", "wormbase": "WBGene00004801", "sbo": "SBO:0000243", "uniprot": "Q20480"}, "name": "sir-2.2", "id": "WBGene00004801"}, {"annotation": {"kegg.genes": "CELE_AC3.2", "wormbase": "WBGene00007070", "sbo": "SBO:0000243", "uniprot": "Q17399"}, "name": "ugt-49", "id": "WBGene00007070"}, {"annotation": {"kegg.genes": "CELE_C18C4.3", "wormbase": "WBGene00015965", "sbo": "SBO:0000243", "uniprot": "Q18081"}, "name": "ugt-48", "id": "WBGene00015965"}, {"annotation": {"kegg.genes": "CELE_F13D12.4", "wormbase": "WBGene00000114", "sbo": "SBO:0000243", "uniprot": ["Q7JMI1", "P52713"]}, "name": "alh-8", "id": "WBGene00000114"}, {"annotation": {"kegg.genes": "CELE_F55A11.5", "wormbase": "WBGene00044631", "sbo": "SBO:0000243", "uniprot": "Q20800"}, "name": "bus-18", "id": "WBGene00044631"}, {"annotation": {"kegg.genes": "CELE_C34C6.5", "wormbase": "WBGene00007918", "sbo": "SBO:0000243", "uniprot": "Q18425"}, "name": "sphk-1", "id": "WBGene00007918"}, {"annotation": {"kegg.genes": "CELE_F13B12.4", "wormbase": "WBGene00008732", "sbo": "SBO:0000243", "uniprot": "Q19374"}, "name": "F13B12.4", "id": "WBGene00008732"}, {"annotation": {"kegg.genes": "CELE_F01D4.1", "wormbase": "WBGene00008485", "sbo": "SBO:0000243", "uniprot": ["O17756", "D5MCT5"]}, "name": "ugt-43", "id": "WBGene00008485"}, {"annotation": {"kegg.genes": "CELE_C05D2.4", "wormbase": "WBGene00000239", "sbo": "SBO:0000243", "uniprot": ["H2KYG4", "O45137"]}, "name": "bas-1", "id": "WBGene00000239"}, {"annotation": {"kegg.genes": "CELE_C52B9.1", "wormbase": "WBGene00000510", "sbo": "SBO:0000243", "uniprot": ["Q22942", "Q2XN11"]}, "name": "cka-2", "id": "WBGene00000510"}, {"annotation": {"kegg.genes": "CELE_C33H5.18", "wormbase": "WBGene00016384", "sbo": "SBO:0000243", "uniprot": "P53439"}, "name": "cdgs-1", "id": "WBGene00016384"}, {"annotation": {"kegg.genes": "CELE_B0464.1", "wormbase": "WBGene00001094", "sbo": "SBO:0000243", "uniprot": "Q03577"}, "name": "dars-1", "id": "WBGene00001094"}, {"annotation": {"kegg.genes": "CELE_B0310.5", "wormbase": "WBGene00015141", "sbo": "SBO:0000243", "uniprot": "Q10941"}, "name": "ugt-46", "id": "WBGene00015141"}, {"annotation": {"kegg.genes": "CELE_Y37E11AR.5", "wormbase": "WBGene00021372", "sbo": "SBO:0000243", "uniprot": "Q965X5"}, "name": "ugt-45", "id": "WBGene00021372"}, {"annotation": {"kegg.genes": "CELE_F01D4.2", "wormbase": "WBGene00008486", "sbo": "SBO:0000243", "uniprot": "O17757"}, "name": "ugt-44", "id": "WBGene00008486"}, {"annotation": {"kegg.genes": "CELE_R10H10.6", "wormbase": "WBGene00011224", "sbo": "SBO:0000243", "uniprot": "Q21918"}, "name": "R10H10.6", "id": "WBGene00011224"}, {"annotation": {"kegg.genes": "CELE_Y50E8A.6", "wormbase": "WBGene00013049", "sbo": "SBO:0000243", "uniprot": "Q9NAF2"}, "name": "Y50E8A.6", "id": "WBGene00013049"}, {"annotation": {"kegg.genes": "CELE_Y41D4A.6", "wormbase": "WBGene00021508", "sbo": "SBO:0000243", "uniprot": "Q95Y25"}, "name": "Y41D4A.6", "id": "WBGene00021508"}, {"annotation": {"kegg.genes": "CELE_M02D8.4", "wormbase": "WBGene00019730", "sbo": "SBO:0000243", "uniprot": ["Q65ZI9", "Q8IG01", "Q21463"]}, "name": "asns-2", "id": "WBGene00019730"}, {"annotation": {"kegg.genes": "CELE_F01D5.9", "wormbase": "WBGene00008499", "sbo": "SBO:0000243", "uniprot": "Q9XVA6"}, "name": "cyp-37A1", "id": "WBGene00008499"}, {"annotation": {"kegg.genes": "CELE_Y54E5A.1", "wormbase": "WBGene00013197", "sbo": "SBO:0000243", "uniprot": "G5EC63"}, "name": "ttm-5", "id": "WBGene00013197"}, {"annotation": {"kegg.genes": "CELE_F57C9.1", "wormbase": "WBGene00019008", "sbo": "SBO:0000243", "uniprot": ["H1ZUV6", "G8JXZ7", "O01824"]}, "name": "pdxk-1", "id": "WBGene00019008"}, {"annotation": {"kegg.genes": "CELE_D1037.3", "wormbase": "WBGene00001501", "sbo": "SBO:0000243", "uniprot": "Q9TYS3"}, "name": "ftn-2", "id": "WBGene00001501"}, {"annotation": {"kegg.genes": "CELE_C03G5.1", "wormbase": "WBGene00015391", "sbo": "SBO:0000243", "uniprot": "Q09508"}, "name": "sdha-1", "id": "WBGene00015391"}, {"annotation": {"kegg.genes": "CELE_F02A9.4", "wormbase": "WBGene00008514", "sbo": "SBO:0000243", "uniprot": ["P34384", "P34385"]}, "name": "F02A9.4", "id": "WBGene00008514"}, {"annotation": {"kegg.genes": "CELE_T13C5.5", "wormbase": "WBGene00000245", "sbo": "SBO:0000243", "uniprot": "Q22460"}, "name": "bca-1", "id": "WBGene00000245"}, {"annotation": {"kegg.genes": "CELE_Y116A8C.28", "wormbase": "WBGene00013805", "sbo": "SBO:0000243", "uniprot": ["D3NQB0", "D3NQA9", "Q8I102", "Q2YS41"]}, "name": "bca-2", "id": "WBGene00013805"}, {"annotation": {"kegg.genes": "CELE_Y47D3A.29", "wormbase": "WBGene00012936", "sbo": "SBO:0000243", "uniprot": ["C7IVS4", "Q9NAH1"]}, "name": "Y47D3A.29", "id": "WBGene00012936"}, {"annotation": {"kegg.genes": "CELE_C10C5.5", "wormbase": "WBGene00007509", "sbo": "SBO:0000243", "uniprot": "Q17900"}, "name": "C10C5.5", "id": "WBGene00007509"}, {"annotation": {"kegg.genes": "CELE_C10C5.4", "wormbase": "WBGene00007508", "sbo": "SBO:0000243", "uniprot": "Q17899"}, "name": "C10C5.4", "id": "WBGene00007508"}, {"annotation": {"kegg.genes": "CELE_C06G3.5", "wormbase": "WBGene00015551", "sbo": "SBO:0000243", "uniprot": ["H2KYI5", "Q86NI2"]}, "name": "C06G3.5", "id": "WBGene00015551"}, {"annotation": {"kegg.genes": "CELE_B0432.5", "wormbase": "WBGene00000296", "sbo": "SBO:0000243", "uniprot": "P90986"}, "name": "cat-2", "id": "WBGene00000296"}, {"annotation": {"kegg.genes": "CELE_F10D11.1", "wormbase": "WBGene00004931", "sbo": "SBO:0000243", "uniprot": "P31161"}, "name": "sod-2", "id": "WBGene00004931"}, {"annotation": {"kegg.genes": "CELE_C08A9.1", "wormbase": "WBGene00004932", "sbo": "SBO:0000243", "uniprot": "P41977"}, "name": "sod-3", "id": "WBGene00004932"}, {"annotation": {"kegg.genes": "CELE_K10D2.7", "wormbase": "WBGene00019633", "sbo": "SBO:0000243", "uniprot": "Q09412"}, "name": "K10D2.7", "id": "WBGene00019633"}, {"annotation": {"kegg.genes": "CELE_ZK430.3", "wormbase": "WBGene00007036", "sbo": "SBO:0000243", "uniprot": "Q27538"}, "name": "sod-5", "id": "WBGene00007036"}, {"annotation": {"kegg.genes": "CELE_F37B12.2", "wormbase": "WBGene00001527", "sbo": "SBO:0000243", "uniprot": "Q20117"}, "name": "gcs-1", "id": "WBGene00001527"}, {"annotation": {"kegg.genes": "CELE_Y65B4A.8", "wormbase": "WBGene00022031", "sbo": "SBO:0000243", "uniprot": "Q9BL56"}, "name": "Y65B4A.8", "id": "WBGene00022031"}, {"annotation": {"kegg.genes": "CELE_T13G4.4", "wormbase": "WBGene00020491", "sbo": "SBO:0000243", "uniprot": "Q966F6"}, "name": "T13G4.4", "id": "WBGene00020491"}, {"annotation": {"kegg.genes": "CELE_ZK858.1", "wormbase": "WBGene00014115", "sbo": "SBO:0000243", "uniprot": "G5EFL0"}, "name": "gld-4", "id": "WBGene00014115"}, {"annotation": {"kegg.genes": "CELE_Y47G6A.9", "wormbase": "WBGene00021638", "sbo": "SBO:0000243", "uniprot": "Q9N3T3"}, "name": "Y47G6A.9", "id": "WBGene00021638"}, {"annotation": {"kegg.genes": "CELE_ZC308.1", "wormbase": "WBGene00001596", "sbo": "SBO:0000243", "uniprot": "O17087"}, "name": "gld-2", "id": "WBGene00001596"}, {"annotation": {"kegg.genes": "CELE_T07A9.6", "wormbase": "WBGene00000913", "sbo": "SBO:0000243", "uniprot": "G5EE01"}, "name": "daf-18", "id": "WBGene00000913"}, {"annotation": {"kegg.genes": "CELE_C10F3.4", "wormbase": "WBGene00015678", "sbo": "SBO:0000243", "uniprot": "Q5ZR76"}, "name": "mcp-1", "id": "WBGene00015678"}, {"annotation": {"kegg.genes": "CELE_Y54G11A.6", "wormbase": "WBGene00000830", "sbo": "SBO:0000243", "uniprot": "O61235"}, "name": "ctl-1", "id": "WBGene00000830"}, {"annotation": {"kegg.genes": "CELE_Y54G11A.13", "wormbase": "WBGene00013220", "sbo": "SBO:0000243", "uniprot": "Q8MYL7"}, "name": "ctl-3", "id": "WBGene00013220"}, {"annotation": {"kegg.genes": "CELE_Y54G11A.5", "wormbase": "WBGene00000831", "sbo": "SBO:0000243", "uniprot": "Q27487"}, "name": "ctl-2", "id": "WBGene00000831"}, {"annotation": {"kegg.genes": "CELE_Y87G2A.5", "wormbase": "WBGene00006936", "sbo": "SBO:0000243", "uniprot": "Q9U1Q4"}, "name": "glp-4", "id": "WBGene00006936"}, {"annotation": {"kegg.genes": "CELE_ZK721.1", "wormbase": "WBGene00006477", "sbo": "SBO:0000243", "uniprot": ["H2L0H8", "Q9GYF0", "H2L0H7"]}, "name": "chup-1", "id": "WBGene00006477"}, {"annotation": {"kegg.genes": "CELE_Y71H10A.2", "wormbase": "WBGene00022200", "sbo": "SBO:0000243", "uniprot": "Q9TZL9"}, "name": "fard-1", "id": "WBGene00022200"}, {"annotation": {"kegg.genes": "CELE_Y105E8B.9", "wormbase": "WBGene00013693", "sbo": "SBO:0000243", "uniprot": "Q95Q32"}, "name": "Y105E8B.9", "id": "WBGene00013693"}, {"annotation": {"kegg.genes": "CYTB", "wormbase": "WBGene00000829", "sbo": "SBO:0000243", "uniprot": ["G5EDJ2", "P24890"]}, "name": "ctb-1", "id": "WBGene00000829"}, {"annotation": {"kegg.genes": "CELE_F56B6.4", "wormbase": "WBGene00006863", "sbo": "SBO:0000243", "uniprot": ["Q95Q50", "H2KYQ5", "H2KYQ6"]}, "name": "gyg-1", "id": "WBGene00006863"}, {"annotation": {"kegg.genes": "CELE_T08B2.9", "wormbase": "WBGene00001497", "sbo": "SBO:0000243", "uniprot": ["Q9GYS8", "Q86B36"]}, "name": "fars-1", "id": "WBGene00001497"}, {"annotation": {"kegg.genes": "CELE_C23H3.4", "wormbase": "WBGene00016020", "sbo": "SBO:0000243", "uniprot": "P91079"}, "name": "sptl-1", "id": "WBGene00016020"}, {"annotation": {"kegg.genes": "CELE_Y105C5B.28", "wormbase": "WBGene00001604", "sbo": "SBO:0000243", "uniprot": ["Q9U307", "H8ESF5", "Q2HQL4"]}, "name": "gln-3", "id": "WBGene00001604"}, {"annotation": {"kegg.genes": "CELE_C17G1.7", "wormbase": "WBGene00007653", "sbo": "SBO:0000243", "uniprot": "Q93244"}, "name": "cysl-1", "id": "WBGene00007653"}, {"annotation": {"kegg.genes": "CELE_K10H10.2", "wormbase": "WBGene00010759", "sbo": "SBO:0000243", "uniprot": "O45679"}, "name": "cysl-2", "id": "WBGene00010759"}, {"annotation": {"kegg.genes": "CELE_C34B7.4", "wormbase": "WBGene00007914", "sbo": "SBO:0000243", "uniprot": "Q95ZX6"}, "name": "mys-4", "id": "WBGene00007914"}, {"annotation": {"kegg.genes": "CELE_F59A7.9", "wormbase": "WBGene00019096", "sbo": "SBO:0000243", "uniprot": "O16284"}, "name": "cysl-4", "id": "WBGene00019096"}, {"annotation": {"kegg.genes": "CELE_Y63D3A.7", "wormbase": "WBGene00013406", "sbo": "SBO:0000243", "uniprot": "Q9XWG2"}, "name": "Y63D3A.7", "id": "WBGene00013406"}, {"annotation": {"kegg.genes": "CELE_F10D2.7", "wormbase": "WBGene00017333", "sbo": "SBO:0000243", "uniprot": "O16916"}, "name": "ugt-38", "id": "WBGene00017333"}, {"annotation": {"kegg.genes": "CELE_F10D2.2", "wormbase": "WBGene00017329", "sbo": "SBO:0000243", "uniprot": ["Q8IA78", "H2KZP8"]}, "name": "ugt-39", "id": "WBGene00017329"}, {"annotation": {"kegg.genes": "CELE_F09G2.6", "wormbase": "WBGene00017315", "sbo": "SBO:0000243", "uniprot": "O17401"}, "name": "ugt-36", "id": "WBGene00017315"}, {"annotation": {"kegg.genes": "CELE_F10D2.6", "wormbase": "WBGene00017332", "sbo": "SBO:0000243", "uniprot": "O16915"}, "name": "ugt-37", "id": "WBGene00017332"}, {"annotation": {"kegg.genes": "CELE_F29F11.2", "wormbase": "WBGene00009255", "sbo": "SBO:0000243", "uniprot": "G5EES5"}, "name": "ugt-34", "id": "WBGene00009255"}, {"annotation": {"kegg.genes": "CELE_C32C4.7", "wormbase": "WBGene00044286", "sbo": "SBO:0000243", "uniprot": "Q52GY8"}, "name": "ugt-35", "id": "WBGene00044286"}, {"annotation": {"kegg.genes": "CELE_T10B10.2", "wormbase": "WBGene00011679", "sbo": "SBO:0000243", "uniprot": "Q22370"}, "name": "ucr-2.2", "id": "WBGene00011679"}, {"annotation": {"kegg.genes": "CELE_C35A5.2", "wormbase": "WBGene00007946", "sbo": "SBO:0000243", "uniprot": "Q18470"}, "name": "ugt-33", "id": "WBGene00007946"}, {"annotation": {"kegg.genes": "CELE_T01G5.2", "wormbase": "WBGene00011340", "sbo": "SBO:0000243", "uniprot": "O18009"}, "name": "ugt-30", "id": "WBGene00011340"}, {"annotation": {"kegg.genes": "CELE_VW06B3R.1", "wormbase": "WBGene00012158", "sbo": "SBO:0000243", "uniprot": ["G5EDD1", "G5ED31"]}, "name": "ucr-2.1", "id": "WBGene00012158"}, {"annotation": {"kegg.genes": "CELE_F01G10.2", "wormbase": "WBGene00001157", "sbo": "SBO:0000243", "uniprot": "O17761"}, "name": "ech-8", "id": "WBGene00001157"}, {"annotation": {"kegg.genes": "CELE_Y105E8A.20", "wormbase": "WBGene00013678", "sbo": "SBO:0000243", "uniprot": ["B3KYC0", "Q8WQA1"]}, "name": "Y105E8A.20", "id": "WBGene00013678"}, {"annotation": {"kegg.genes": "CELE_R06A4.7", "wormbase": "WBGene00003220", "sbo": "SBO:0000243", "uniprot": "O17514"}, "name": "mes-2", "id": "WBGene00003220"}, {"annotation": {"kegg.genes": "CELE_F59C6.5", "wormbase": "WBGene00010326", "sbo": "SBO:0000243", "uniprot": "Q93831"}, "name": "F59C6.5", "id": "WBGene00010326"}, {"annotation": {"kegg.genes": "CELE_Y71H2AM.5", "wormbase": "WBGene00022170", "sbo": "SBO:0000243", "uniprot": "Q9BL34"}, "name": "Y71H2AM.5", "id": "WBGene00022170"}, {"annotation": {"kegg.genes": "CELE_R11A5.4", "wormbase": "WBGene00011232", "sbo": "SBO:0000243", "uniprot": ["Q7JKI1", "Q7JKI2", "Q7JKI3", "O02286"]}, "name": "pck-2", "id": "WBGene00011232"}, {"annotation": {"kegg.genes": "CELE_Y6B3B.10", "wormbase": "WBGene00006505", "sbo": "SBO:0000243", "uniprot": "Q9XWE9"}, "name": "lagr-1", "id": "WBGene00006505"}, {"annotation": {"kegg.genes": "CELE_F09F7.3", "wormbase": "WBGene00017300", "sbo": "SBO:0000243", "uniprot": "Q27492"}, "name": "rpc-2", "id": "WBGene00017300"}, {"annotation": {"kegg.genes": "CELE_Y70D2A.2", "wormbase": "WBGene00013497", "sbo": "SBO:0000243", "uniprot": "G5EEC8"}, "name": "hex-5", "id": "WBGene00013497"}, {"annotation": {"kegg.genes": "CELE_Y51F10.5", "wormbase": "WBGene00021766", "sbo": "SBO:0000243", "uniprot": "Q8WTK2"}, "name": "hex-4", "id": "WBGene00021766"}, {"annotation": {"kegg.genes": "CELE_K01H12.2", "wormbase": "WBGene00010485", "sbo": "SBO:0000243", "uniprot": "G5EFW8"}, "name": "ant-1.3", "id": "WBGene00010485"}, {"annotation": {"kegg.genes": "CELE_E01F3.1", "wormbase": "WBGene00008443", "sbo": "SBO:0000243", "uniprot": "Q8I0P7"}, "name": "pde-3", "id": "WBGene00008443"}, {"annotation": {"kegg.genes": "CELE_F28H1.3", "wormbase": "WBGene00000197", "sbo": "SBO:0000243", "uniprot": "O01541"}, "name": "aars-2", "id": "WBGene00000197"}, {"annotation": {"kegg.genes": "CELE_F26D10.10", "wormbase": "WBGene00001606", "sbo": "SBO:0000243", "uniprot": "Q9XVU2"}, "name": "gln-5", "id": "WBGene00001606"}, {"annotation": {"kegg.genes": "CELE_Y39A1C.4", "wormbase": "WBGene00012663", "sbo": "SBO:0000243", "uniprot": "G5EDG9"}, "name": "hex-3", "id": "WBGene00012663"}, {"annotation": {"kegg.genes": "CELE_W02B12.6", "wormbase": "WBGene00000196", "sbo": "SBO:0000243", "uniprot": "Q23122"}, "name": "aars-1", "id": "WBGene00000196"}, {"annotation": {"kegg.genes": "CELE_W09C3.4", "wormbase": "WBGene00021112", "sbo": "SBO:0000243", "uniprot": "P91529"}, "name": "W09C3.4", "id": "WBGene00021112"}, {"annotation": {"kegg.genes": "CELE_Y48G9A.10", "wormbase": "WBGene00021703", "sbo": "SBO:0000243", "uniprot": "Q9N3N3"}, "name": "cpt-3", "id": "WBGene00021703"}, {"annotation": {"kegg.genes": "CELE_C17G1.3", "wormbase": "WBGene00007650", "sbo": "SBO:0000243", "uniprot": ["Q0G821", "Q93242"]}, "name": "ugt-23", "id": "WBGene00007650"}, {"annotation": {"kegg.genes": "CELE_F32B6.2", "wormbase": "WBGene00009319", "sbo": "SBO:0000243", "uniprot": "O45430"}, "name": "mccc-1", "id": "WBGene00009319"}, {"annotation": {"kegg.genes": "CELE_R09D1.14", "wormbase": "WBGene00011170", "sbo": "SBO:0000243", "uniprot": "Q9NAN7"}, "name": "R09D1.14", "id": "WBGene00011170"}, {"annotation": {"kegg.genes": "CELE_F28D1.11", "wormbase": "WBGene00009219", "sbo": "SBO:0000243", "uniprot": "Q9XVV5"}, "name": "dpm-3", "id": "WBGene00009219"}, {"annotation": {"kegg.genes": "COX3", "wormbase": "WBGene00010962", "sbo": "SBO:0000243", "uniprot": ["G5EFH2", "P24891"]}, "name": "ctc-3", "id": "WBGene00010962"}, {"annotation": {"kegg.genes": "CELE_Y66H1A.2", "wormbase": "WBGene00022044", "sbo": "SBO:0000243", "uniprot": "Q9TYJ7"}, "name": "dpm-1", "id": "WBGene00022044"}, {"annotation": {"kegg.genes": "COX1", "wormbase": "WBGene00010964", "sbo": "SBO:0000243", "uniprot": "P24893"}, "name": "ctc-1", "id": "WBGene00010964"}, {"annotation": {"kegg.genes": "CELE_C14F11.1", "wormbase": "WBGene00015778", "sbo": "SBO:0000243", "uniprot": ["Q8MQD9", "Q17994"]}, "name": "got-2.2", "id": "WBGene00015778"}, {"annotation": {"kegg.genes": "CELE_T27A10.3", "wormbase": "WBGene00000515", "sbo": "SBO:0000243", "uniprot": ["Q86MJ6", "Q22820"]}, "name": "ckc-1", "id": "WBGene00000515"}, {"annotation": {"kegg.genes": "CELE_R06F6.9", "wormbase": "WBGene00001153", "sbo": "SBO:0000243", "uniprot": "Q09603"}, "name": "ech-4", "id": "WBGene00001153"}, {"annotation": {"kegg.genes": "CELE_C44E4.3", "wormbase": "WBGene00016652", "sbo": "SBO:0000243", "uniprot": "O01804"}, "name": "got-2.1", "id": "WBGene00016652"}, {"annotation": {"kegg.genes": "CELE_C01F1.3", "wormbase": "WBGene00015298", "sbo": "SBO:0000243", "uniprot": ["Q2L6W1", "Q17556"]}, "name": "C01F1.3", "id": "WBGene00015298"}, {"annotation": {"kegg.genes": "CELE_F42G9.5", "wormbase": "WBGene00000117", "sbo": "SBO:0000243", "uniprot": ["Q20352", "Q8MNS6"]}, "name": "alh-11", "id": "WBGene00000117"}, {"annotation": {"kegg.genes": "CELE_C05D11.7", "wormbase": "WBGene00015484", "sbo": "SBO:0000243", "uniprot": ["Q8T3F2", "Q11186"]}, "name": "atgl-1", "id": "WBGene00015484"}, {"annotation": {"kegg.genes": "CELE_T08B2.7", "wormbase": "WBGene00020347", "sbo": "SBO:0000243", "uniprot": ["Q9GYT0", "Q9BIC3", "Q8T8N8"]}, "name": "ech-1.2", "id": "WBGene00020347"}, {"annotation": {"kegg.genes": "CELE_T10B11.2", "wormbase": "WBGene00020398", "sbo": "SBO:0000243", "uniprot": "Q9TZI1"}, "name": "cerk-1", "id": "WBGene00020398"}, {"annotation": {"kegg.genes": "CELE_F26C11.1", "wormbase": "WBGene00009146", "sbo": "SBO:0000243", "uniprot": "Q09549"}, "name": "F26C11.1", "id": "WBGene00009146"}, {"annotation": {"kegg.genes": "CELE_E04A4.7", "wormbase": "WBGene00017121", "sbo": "SBO:0000243", "uniprot": "P19974"}, "name": "cyc-2.1", "id": "WBGene00017121"}, {"annotation": {"kegg.genes": "CELE_H14A12.2", "wormbase": "WBGene00001503", "sbo": "SBO:0000243", "uniprot": ["O17214", "Q8ITZ0"]}, "name": "fum-1", "id": "WBGene00001503"}, {"annotation": {"kegg.genes": "CELE_Y49E10.22", "wormbase": "WBGene00013041", "sbo": "SBO:0000243", "uniprot": "Q9XTU1"}, "name": "pstk-1", "id": "WBGene00013041"}, {"annotation": {"kegg.genes": "CELE_R05F9.12", "wormbase": "WBGene00019895", "sbo": "SBO:0000243", "uniprot": "Q21750"}, "name": "aagr-2", "id": "WBGene00019895"}, {"annotation": {"kegg.genes": "CELE_F32H2.5", "wormbase": "WBGene00009342", "sbo": "SBO:0000243", "uniprot": "P91871"}, "name": "fasn-1", "id": "WBGene00009342"}, {"annotation": {"kegg.genes": "CELE_T07C4.7", "wormbase": "WBGene00003225", "sbo": "SBO:0000243", "uniprot": "P41956"}, "name": "mev-1", "id": "WBGene00003225"}, {"annotation": {"kegg.genes": "CELE_T10F2.1", "wormbase": "WBGene00001744", "sbo": "SBO:0000243", "uniprot": ["Q10039", "Q8I711"]}, "name": "gars-1", "id": "WBGene00001744"}, {"annotation": {"kegg.genes": "CELE_Y97E10AR.2", "wormbase": "WBGene00022397", "sbo": "SBO:0000243", "uniprot": ["Q7KX02", "H2L030"]}, "name": "Y97E10AR.2", "id": "WBGene00022397"}, {"annotation": {"kegg.genes": "CELE_F42A8.2", "wormbase": "WBGene00006433", "sbo": "SBO:0000243", "uniprot": "Q09545"}, "name": "sdhb-1", "id": "WBGene00006433"}, {"annotation": {"kegg.genes": "CELE_M05D6.7", "wormbase": "WBGene00001523", "sbo": "SBO:0000243", "uniprot": "Q21526"}, "name": "gbh-2", "id": "WBGene00001523"}, {"annotation": {"kegg.genes": "CELE_D2089.5", "wormbase": "WBGene00001522", "sbo": "SBO:0000243", "uniprot": "Q19000"}, "name": "gbh-1", "id": "WBGene00001522"}, {"annotation": {"kegg.genes": "CELE_ZK637.10", "wormbase": "WBGene00014028", "sbo": "SBO:0000243", "uniprot": "P30635"}, "name": "trxr-2", "id": "WBGene00014028"}, {"annotation": {"kegg.genes": "CELE_B0228.7", "wormbase": "WBGene00015064", "sbo": "SBO:0000243", "uniprot": "Q09438"}, "name": "B0228.7", "id": "WBGene00015064"}, {"annotation": {"kegg.genes": "CELE_ZC262.5", "wormbase": "WBGene00022582", "sbo": "SBO:0000243", "uniprot": "P34539"}, "name": "ZC262.5", "id": "WBGene00022582"}, {"annotation": {"kegg.genes": "CELE_Y51H1A.3", "wormbase": "WBGene00013094", "sbo": "SBO:0000243", "uniprot": ["Q9XWJ5", "Q9XWJ6"]}, "name": "Y51H1A.3", "id": "WBGene00013094"}, {"annotation": {"kegg.genes": "CELE_R07B7.11", "wormbase": "WBGene00011095", "sbo": "SBO:0000243", "uniprot": "Q21801"}, "name": "gana-1", "id": "WBGene00011095"}, {"annotation": {"kegg.genes": "CELE_D2085.6", "wormbase": "WBGene00008431", "sbo": "SBO:0000243", "uniprot": "Q18993"}, "name": "piga-1", "id": "WBGene00008431"}, {"annotation": {"kegg.genes": "CELE_R186.4", "wormbase": "WBGene00003031", "sbo": "SBO:0000243", "uniprot": "G5EF06"}, "name": "lin-46", "id": "WBGene00003031"}, {"annotation": {"kegg.genes": "CELE_F57B10.14", "wormbase": "WBGene00019007", "sbo": "SBO:0000243", "uniprot": "Q8MXI1"}, "name": "ucr-11", "id": "WBGene00019007"}, {"annotation": {"kegg.genes": "CELE_C16C2.3", "wormbase": "WBGene00007620", "sbo": "SBO:0000243", "uniprot": ["O17590", "A5Z2U3"]}, "name": "ocrl-1", "id": "WBGene00007620"}, {"annotation": {"kegg.genes": "CELE_D1005.2", "wormbase": "WBGene00016996", "sbo": "SBO:0000243", "uniprot": "Q18910"}, "name": "D1005.2", "id": "WBGene00016996"}, {"annotation": {"kegg.genes": "CELE_C10F3.6", "wormbase": "WBGene00001508", "sbo": "SBO:0000243", "uniprot": "G5EFE7"}, "name": "fut-8", "id": "WBGene00001508"}, {"annotation": {"kegg.genes": "CELE_C08F8.4", "wormbase": "WBGene00007446", "sbo": "SBO:0000243", "uniprot": ["G5EEY2", "H9G2W5", "H9G2W6"]}, "name": "mboa-4", "id": "WBGene00007446"}, {"annotation": {"kegg.genes": "CELE_Y105E8A.12", "wormbase": "WBGene00013672", "sbo": "SBO:0000243", "uniprot": ["G5EC38", "G5EBE7"]}, "name": "catp-1", "id": "WBGene00013672"}, {"annotation": {"kegg.genes": "CELE_R155.1", "wormbase": "WBGene00020115", "sbo": "SBO:0000243", "uniprot": "O01925"}, "name": "mboa-6", "id": "WBGene00020115"}, {"annotation": {"kegg.genes": "CELE_T03D8.6", "wormbase": "WBGene00011393", "sbo": "SBO:0000243", "uniprot": ["Q9XTY7", "B5BM47"]}, "name": "T03D8.6", "id": "WBGene00011393"}, {"annotation": {"kegg.genes": "CELE_C15F1.6", "wormbase": "WBGene00000198", "sbo": "SBO:0000243", "uniprot": "Q9N5Y2"}, "name": "art-1", "id": "WBGene00000198"}, {"annotation": {"kegg.genes": "CELE_Y69A2AL.2", "wormbase": "WBGene00044468", "sbo": "SBO:0000243", "uniprot": "Q3V5J7"}, "name": "Y69A2AL.2", "id": "WBGene00044468"}, {"annotation": {"kegg.genes": "CELE_H19N07.4", "wormbase": "WBGene00010408", "sbo": "SBO:0000243", "uniprot": ["G5EBH6", "F1LIN4"]}, "name": "mboa-2", "id": "WBGene00010408"}, {"annotation": {"kegg.genes": "CELE_C54G7.2", "wormbase": "WBGene00016934", "sbo": "SBO:0000243", "uniprot": "G5EC53"}, "name": "mboa-3", "id": "WBGene00016934"}, {"annotation": {"kegg.genes": "CELE_C01G12.8", "wormbase": "WBGene00007248", "sbo": "SBO:0000243", "uniprot": "G5EFV6"}, "name": "catp-4", "id": "WBGene00007248"}, {"annotation": {"kegg.genes": "CELE_ZK353.6", "wormbase": "WBGene00002249", "sbo": "SBO:0000243", "uniprot": "P34629"}, "name": "lap-1", "id": "WBGene00002249"}, {"annotation": {"kegg.genes": "CELE_C50F7.4", "wormbase": "WBGene00016844", "sbo": "SBO:0000243", "uniprot": "P53589"}, "name": "sucg-1", "id": "WBGene00016844"}, {"annotation": {"kegg.genes": "CELE_R11F4.1", "wormbase": "WBGene00020007", "sbo": "SBO:0000243", "uniprot": "Q21944"}, "name": "R11F4.1", "id": "WBGene00020007"}, {"annotation": {"kegg.genes": "CELE_C02E7.1", "wormbase": "WBGene00015338", "sbo": "SBO:0000243", "uniprot": "O16436"}, "name": "catp-2", "id": "WBGene00015338"}, {"annotation": {"kegg.genes": "ND4", "wormbase": "WBGene00010963", "sbo": "SBO:0000243", "uniprot": ["P24892", "G5EF66"]}, "name": "nduo-4", "id": "WBGene00010963"}, {"annotation": {"kegg.genes": "CELE_W07G4.4", "wormbase": "WBGene00002250", "sbo": "SBO:0000243", "uniprot": "Q27245"}, "name": "lap-2", "id": "WBGene00002250"}, {"annotation": {"kegg.genes": "CELE_T27F6.6", "wormbase": "WBGene00012105", "sbo": "SBO:0000243", "uniprot": "O45870"}, "name": "T27F6.6", "id": "WBGene00012105"}, {"annotation": {"kegg.genes": "CELE_R02D3.1", "wormbase": "WBGene00019819", "sbo": "SBO:0000243", "uniprot": "O44503"}, "name": "R02D3.1", "id": "WBGene00019819"}, {"annotation": {"kegg.genes": "CELE_C26E6.9", "wormbase": "WBGene00004782", "sbo": "SBO:0000243", "uniprot": "Q18221"}, "name": "set-2", "id": "WBGene00004782"}, {"annotation": {"kegg.genes": "CELE_Y48B6A.13", "wormbase": "WBGene00012984", "sbo": "SBO:0000243", "uniprot": ["Q9U294", "Q9U2A1"]}, "name": "Y48B6A.13", "id": "WBGene00012984"}, {"annotation": {"kegg.genes": "CELE_F43G9.1", "wormbase": "WBGene00009664", "sbo": "SBO:0000243", "uniprot": "Q93714"}, "name": "idha-1", "id": "WBGene00009664"}, {"annotation": {"kegg.genes": "CELE_Y71H10A.1", "wormbase": "WBGene00022199", "sbo": "SBO:0000243", "uniprot": "Q9TZL8"}, "name": "pfk-1.1", "id": "WBGene00022199"}, {"annotation": {"kegg.genes": "CELE_C33A12.1", "wormbase": "WBGene00007880", "sbo": "SBO:0000243", "uniprot": "Q18359"}, "name": "C33A12.1", "id": "WBGene00007880"}, {"annotation": {"kegg.genes": "CELE_C32D5.5", "wormbase": "WBGene00016313", "sbo": "SBO:0000243", "uniprot": "Q09265"}, "name": "set-4", "id": "WBGene00016313"}, {"annotation": {"kegg.genes": "CELE_T19B4.3", "wormbase": "WBGene00020557", "sbo": "SBO:0000243", "uniprot": "P91455"}, "name": "T19B4.3", "id": "WBGene00020557"}, {"annotation": {"kegg.genes": "CELE_C27A7.3", "wormbase": "WBGene00007755", "sbo": "SBO:0000243", "uniprot": ["E3W744", "E3W745", "P90755"]}, "name": "C27A7.3", "id": "WBGene00007755"}, {"annotation": {"kegg.genes": "CELE_C37E2.1", "wormbase": "WBGene00007993", "sbo": "SBO:0000243", "uniprot": "Q93353"}, "name": "idhb-1", "id": "WBGene00007993"}, {"annotation": {"kegg.genes": "CELE_C27A7.1", "wormbase": "WBGene00007753", "sbo": "SBO:0000243", "uniprot": ["B5BM33", "E1B6U2", "P90754"]}, "name": "C27A7.1", "id": "WBGene00007753"}, {"annotation": {"kegg.genes": "CELE_T04A8.7", "wormbase": "WBGene00011409", "sbo": "SBO:0000243", "uniprot": ["Q86G92", "Q22137"]}, "name": "T04A8.7", "id": "WBGene00011409"}, {"annotation": {"kegg.genes": "CELE_C27A7.5", "wormbase": "WBGene00007756", "sbo": "SBO:0000243", "uniprot": ["A5Z2U6", "P90759", "P90758", "Q9U3P0", "A5Z2U5"]}, "name": "C27A7.5", "id": "WBGene00007756"}, {"annotation": {"kegg.genes": "CELE_F12F6.7", "wormbase": "WBGene00008722", "sbo": "SBO:0000243", "uniprot": "Q19366"}, "name": "F12F6.7", "id": "WBGene00008722"}, {"annotation": {"kegg.genes": "CELE_T23G11.2", "wormbase": "WBGene00001647", "sbo": "SBO:0000243", "uniprot": "G5EC27"}, "name": "gna-2", "id": "WBGene00001647"}, {"annotation": {"kegg.genes": "CELE_Y47D7A.14", "wormbase": "WBGene00021626", "sbo": "SBO:0000243", "uniprot": ["G4SDH4", "Q95XZ2"]}, "name": "rft-2", "id": "WBGene00021626"}, {"annotation": {"kegg.genes": "CELE_R12E2.11", "wormbase": "WBGene00020036", "sbo": "SBO:0000243", "uniprot": "O61790"}, "name": "R12E2.11", "id": "WBGene00020036"}, {"annotation": {"kegg.genes": "CELE_W09C5.8", "wormbase": "WBGene00012354", "sbo": "SBO:0000243", "uniprot": "Q9U329"}, "name": "W09C5.8", "id": "WBGene00012354"}, {"annotation": {"kegg.genes": "CELE_M05B5.4", "wormbase": "WBGene00010872", "sbo": "SBO:0000243", "uniprot": "Q21515"}, "name": "M05B5.4", "id": "WBGene00010872"}, {"annotation": {"kegg.genes": "CELE_K02F2.2", "wormbase": "WBGene00019322", "sbo": "SBO:0000243", "uniprot": "P27604"}, "name": "ahcy-1", "id": "WBGene00019322"}, {"annotation": {"kegg.genes": "CELE_T14D7.1", "wormbase": "WBGene00011767", "sbo": "SBO:0000243", "uniprot": "Q94055"}, "name": "agxt-1", "id": "WBGene00011767"}, {"annotation": {"kegg.genes": "CELE_F53C3.13", "wormbase": "WBGene00018756", "sbo": "SBO:0000243", "uniprot": ["Q9TXU1", "H2KZD2", "H2KZD1"]}, "name": "F53C3.13", "id": "WBGene00018756"}, {"annotation": {"kegg.genes": "CELE_F56B3.5", "wormbase": "WBGene00001154", "sbo": "SBO:0000243", "uniprot": "O45106"}, "name": "ech-5", "id": "WBGene00001154"}, {"annotation": {"kegg.genes": "CELE_Y45F10A.4", "wormbase": "WBGene00012867", "sbo": "SBO:0000243", "uniprot": "O62461"}, "name": "seld-1", "id": "WBGene00012867"}, {"annotation": {"kegg.genes": "CELE_K08D10.2", "wormbase": "WBGene00001033", "sbo": "SBO:0000243", "uniprot": "Q21324"}, "name": "dnj-15", "id": "WBGene00001033"}, {"annotation": {"kegg.genes": "CELE_F36H1.6", "wormbase": "WBGene00000109", "sbo": "SBO:0000243", "uniprot": "G5ECV9"}, "name": "alh-3", "id": "WBGene00000109"}, {"annotation": {"kegg.genes": "CELE_K04F1.15", "wormbase": "WBGene00000108", "sbo": "SBO:0000243", "uniprot": "Q9TXM0"}, "name": "alh-2", "id": "WBGene00000108"}, {"annotation": {"kegg.genes": "CELE_F54D8.3", "wormbase": "WBGene00000107", "sbo": "SBO:0000243", "uniprot": ["Q20780", "Q8IG19"]}, "name": "alh-1", "id": "WBGene00000107"}, {"annotation": {"kegg.genes": "CELE_F10C2.4", "wormbase": "WBGene00008645", "sbo": "SBO:0000243", "uniprot": "P90829"}, "name": "F10C2.4", "id": "WBGene00008645"}, {"annotation": {"kegg.genes": "CELE_C29E4.10", "wormbase": "WBGene00016207", "sbo": "SBO:0000243", "uniprot": "Q95QT2"}, "name": "C29E4.10", "id": "WBGene00016207"}, {"annotation": {"kegg.genes": "CELE_F56D12.1", "wormbase": "WBGene00000112", "sbo": "SBO:0000243", "uniprot": ["Q6A593", "G5EC31", "G4RZC3", "Q86N72"]}, "name": "alh-6", "id": "WBGene00000112"}, {"annotation": {"kegg.genes": "CELE_T08B1.3", "wormbase": "WBGene00000111", "sbo": "SBO:0000243", "uniprot": "O44555"}, "name": "alh-5", "id": "WBGene00000111"}, {"annotation": {"kegg.genes": "CELE_Y110A7A.10", "wormbase": "WBGene00000001", "sbo": "SBO:0000243", "uniprot": "G5EDP9"}, "name": "aap-1", "id": "WBGene00000001"}, {"annotation": {"kegg.genes": "CELE_K07A1.2", "wormbase": "WBGene00010609", "sbo": "SBO:0000243", "uniprot": "G5EET2"}, "name": "dut-1", "id": "WBGene00010609"}, {"annotation": {"kegg.genes": "CELE_F01F1.6", "wormbase": "WBGene00000115", "sbo": "SBO:0000243", "uniprot": "P46562"}, "name": "alh-9", "id": "WBGene00000115"}, {"annotation": {"kegg.genes": "CELE_R05D3.6", "wormbase": "WBGene00019880", "sbo": "SBO:0000243", "uniprot": "P34539"}, "name": "R05D3.6", "id": "WBGene00019880"}, {"annotation": {"kegg.genes": "CELE_F55H2.1", "wormbase": "WBGene00004933", "sbo": "SBO:0000243", "uniprot": ["G5ECR5", "P34461"]}, "name": "sod-4", "id": "WBGene00004933"}, {"annotation": {"kegg.genes": "CELE_T05E7.1", "wormbase": "WBGene00020258", "sbo": "SBO:0000243", "uniprot": "O01862"}, "name": "T05E7.1", "id": "WBGene00020258"}, {"annotation": {"kegg.genes": "CELE_B0024.13", "wormbase": "WBGene00007102", "sbo": "SBO:0000243", "uniprot": "Q17428"}, "name": "B0024.13", "id": "WBGene00007102"}, {"annotation": {"kegg.genes": "CELE_F58A4.4", "wormbase": "WBGene00004180", "sbo": "SBO:0000243", "uniprot": ["G3MTW9", "P34471"]}, "name": "pri-1", "id": "WBGene00004180"}, {"annotation": {"kegg.genes": "CELE_F07G11.9", "wormbase": "WBGene00017233", "sbo": "SBO:0000243", "uniprot": "O16237"}, "name": "lmd-4", "id": "WBGene00017233"}, {"annotation": {"kegg.genes": "CELE_F09E5.3", "wormbase": "WBGene00017283", "sbo": "SBO:0000243", "uniprot": "Q19264"}, "name": "F09E5.3", "id": "WBGene00017283"}, {"annotation": {"kegg.genes": "CELE_C39B5.6", "wormbase": "WBGene00016524", "sbo": "SBO:0000243", "uniprot": "Q9N5X5"}, "name": "C39B5.6", "id": "WBGene00016524"}, {"annotation": {"kegg.genes": ["CELE_JC8.10", "CELE_JC8.10a"], "wormbase": "WBGene00006763", "sbo": "SBO:0000243", "uniprot": ["B3CJ53", "G5EEJ9", "G5ECL2", "G5EDR8"]}, "name": "unc-26", "id": "WBGene00006763"}, {"annotation": {"kegg.genes": "CELE_K07E3.4", "wormbase": "WBGene00019492", "sbo": "SBO:0000243", "uniprot": "Q21284"}, "name": "K07E3.4", "id": "WBGene00019492"}, {"annotation": {"kegg.genes": "CELE_B0361.5", "wormbase": "WBGene00015159", "sbo": "SBO:0000243", "uniprot": "Q10949"}, "name": "psd-1", "id": "WBGene00015159"}, {"annotation": {"kegg.genes": "CELE_F49C12.13", "wormbase": "WBGene00009882", "sbo": "SBO:0000243", "uniprot": "Q20591"}, "name": "vha-17", "id": "WBGene00009882"}, {"annotation": {"kegg.genes": "CELE_R02E12.6", "wormbase": "WBGene00019830", "sbo": "SBO:0000243", "uniprot": "Q21642"}, "name": "hrg-1", "id": "WBGene00019830"}, {"annotation": {"kegg.genes": "CELE_T26A5.8", "wormbase": "WBGene00020823", "sbo": "SBO:0000243", "uniprot": "Q22798"}, "name": "T26A5.8", "id": "WBGene00020823"}, {"annotation": {"kegg.genes": "CELE_T18H9.2", "wormbase": "WBGene00000215", "sbo": "SBO:0000243", "uniprot": ["Q86NE0", "Q86NE1"]}, "name": "asp-2", "id": "WBGene00000215"}, {"annotation": {"kegg.genes": "CELE_H22K11.1", "wormbase": "WBGene00000216", "sbo": "SBO:0000243", "uniprot": "P55956"}, "name": "asp-3", "id": "WBGene00000216"}, {"annotation": {"kegg.genes": "CELE_Y39B6A.20", "wormbase": "WBGene00000214", "sbo": "SBO:0000243", "uniprot": "G5EEI4"}, "name": "asp-1", "id": "WBGene00000214"}, {"annotation": {"kegg.genes": "CELE_C07E3.9", "wormbase": "WBGene00007419", "sbo": "SBO:0000243", "uniprot": "Q17790"}, "name": "C07E3.9", "id": "WBGene00007419"}, {"annotation": {"kegg.genes": "CELE_F21F8.3", "wormbase": "WBGene00000218", "sbo": "SBO:0000243", "uniprot": "O01532"}, "name": "asp-5", "id": "WBGene00000218"}, {"annotation": {"kegg.genes": "CELE_C49F5.2", "wormbase": "WBGene00008206", "sbo": "SBO:0000243", "uniprot": "O17679"}, "name": "set-6", "id": "WBGene00008206"}, {"annotation": {"kegg.genes": "CELE_F28H6.3", "wormbase": "WBGene00009232", "sbo": "SBO:0000243", "uniprot": "Q9XX97"}, "name": "nkat-1", "id": "WBGene00009232"}, {"annotation": {"kegg.genes": "CELE_Y37E3.11", "wormbase": "WBGene00021352", "sbo": "SBO:0000243", "uniprot": ["Q9BKU2", "A9D2X7"]}, "name": "Y37E3.11", "id": "WBGene00021352"}, {"annotation": {"kegg.genes": "CELE_Y105E8A.23", "wormbase": "WBGene00013680", "sbo": "SBO:0000243", "uniprot": ["Q8WQA3", "A5PEY3"]}, "name": "rpom-1", "id": "WBGene00013680"}, {"annotation": {"kegg.genes": "CELE_F46F11.5", "wormbase": "WBGene00006919", "sbo": "SBO:0000243", "uniprot": "P91303"}, "name": "vha-10", "id": "WBGene00006919"}, {"annotation": {"kegg.genes": "CELE_T06H11.4", "wormbase": "WBGene00003384", "sbo": "SBO:0000243", "uniprot": "G5EGH2"}, "name": "moc-1", "id": "WBGene00003384"}, {"annotation": {"kegg.genes": "CELE_F27C1.7", "wormbase": "WBGene00000230", "sbo": "SBO:0000243", "uniprot": ["P91283", "Q7JNG1"]}, "name": "atp-3", "id": "WBGene00000230"}, {"annotation": {"kegg.genes": "CELE_F42G8.6", "wormbase": "WBGene00018357", "sbo": "SBO:0000243", "uniprot": "O44510"}, "name": "moc-3", "id": "WBGene00018357"}, {"annotation": {"kegg.genes": "CELE_W01A11.6", "wormbase": "WBGene00003385", "sbo": "SBO:0000243", "uniprot": "Q23069"}, "name": "moc-2", "id": "WBGene00003385"}, {"annotation": {"kegg.genes": "CELE_C48E7.2", "wormbase": "WBGene00016750", "sbo": "SBO:0000243", "uniprot": "Q8IG67"}, "name": "let-611", "id": "WBGene00016750"}, {"annotation": {"kegg.genes": "CELE_C07A9.6", "wormbase": "WBGene00007402", "sbo": "SBO:0000243", "uniprot": "P34317"}, "name": "ugt-60", "id": "WBGene00007402"}, {"annotation": {"kegg.genes": ["CELE_W07A8.2a", "CELE_W07A8.2"], "wormbase": "WBGene00012319", "sbo": "SBO:0000243", "uniprot": ["G5EBV1", "G5EC56", "G5EGD6", "F3Y5P2"]}, "name": "ipla-3", "id": "WBGene00012319"}, {"annotation": {"kegg.genes": "CELE_F47A4.5", "wormbase": "WBGene00009801", "sbo": "SBO:0000243", "uniprot": "Q20500"}, "name": "ipla-2", "id": "WBGene00009801"}, {"annotation": {"kegg.genes": "CELE_C29F3.1", "wormbase": "WBGene00001150", "sbo": "SBO:0000243", "uniprot": "O17612"}, "name": "ech-1.1", "id": "WBGene00001150"}, {"annotation": {"kegg.genes": "CELE_F20B6.2", "wormbase": "WBGene00006921", "sbo": "SBO:0000243", "uniprot": "Q19626"}, "name": "vha-12", "id": "WBGene00006921"}, {"annotation": {"kegg.genes": "CELE_T04B2.5", "wormbase": "WBGene00011423", "sbo": "SBO:0000243", "uniprot": "G5EF58"}, "name": "ipla-7", "id": "WBGene00011423"}, {"annotation": {"kegg.genes": "CELE_Y73B6BL.4", "wormbase": "WBGene00022233", "sbo": "SBO:0000243", "uniprot": "Q8MXR3"}, "name": "ipla-6", "id": "WBGene00022233"}, {"annotation": {"kegg.genes": "CELE_H23L24.2", "wormbase": "WBGene00019229", "sbo": "SBO:0000243", "uniprot": "Q9N5L3"}, "name": "ipla-5", "id": "WBGene00019229"}, {"annotation": {"kegg.genes": "CELE_D1037.5", "wormbase": "WBGene00017026", "sbo": "SBO:0000243", "uniprot": "Q9TYS0"}, "name": "ipla-4", "id": "WBGene00017026"}, {"annotation": {"kegg.genes": "CELE_Y45G12B.3", "wormbase": "WBGene00021564", "sbo": "SBO:0000243", "uniprot": "Q9N4Z0"}, "name": "Y45G12B.3", "id": "WBGene00021564"}, {"annotation": {"kegg.genes": "CELE_M88.1", "wormbase": "WBGene00010904", "sbo": "SBO:0000243", "uniprot": "Q21603"}, "name": "ugt-62", "id": "WBGene00010904"}, {"annotation": {"kegg.genes": "CELE_T03G6.3", "wormbase": "WBGene00020195", "sbo": "SBO:0000243", "uniprot": "Q22129"}, "name": "T03G6.3", "id": "WBGene00020195"}, {"annotation": {"kegg.genes": "CELE_Y39G10AR.6", "wormbase": "WBGene00021464", "sbo": "SBO:0000243", "uniprot": "Q86S61"}, "name": "ugt-31", "id": "WBGene00021464"}, {"annotation": {"kegg.genes": "CELE_C34C6.4", "wormbase": "WBGene00007917", "sbo": "SBO:0000243", "uniprot": "Q18429"}, "name": "C34C6.4", "id": "WBGene00007917"}, {"annotation": {"kegg.genes": "CELE_F59F4.4", "wormbase": "WBGene00010339", "sbo": "SBO:0000243", "uniprot": "Q93841"}, "name": "acl-1", "id": "WBGene00010339"}, {"annotation": {"kegg.genes": "CELE_ZK783.2", "wormbase": "WBGene00022817", "sbo": "SBO:0000243", "uniprot": "Q23588"}, "name": "upp-1", "id": "WBGene00022817"}, {"annotation": {"kegg.genes": "CELE_C49F5.1", "wormbase": "WBGene00008205", "sbo": "SBO:0000243", "uniprot": "O17680"}, "name": "sams-1", "id": "WBGene00008205"}, {"annotation": {"kegg.genes": "CELE_F54G8.2", "wormbase": "WBGene00000960", "sbo": "SBO:0000243", "uniprot": "Q03603"}, "name": "dgk-3", "id": "WBGene00000960"}, {"annotation": {"kegg.genes": "CELE_ZK829.2", "wormbase": "WBGene00001839", "sbo": "SBO:0000243", "uniprot": "P34751"}, "name": "hdl-1", "id": "WBGene00001839"}, {"annotation": {"kegg.genes": "CELE_C06A6.4", "wormbase": "WBGene00015509", "sbo": "SBO:0000243", "uniprot": ["Q17686", "Q5WRS4"]}, "name": "C06A6.4", "id": "WBGene00015509"}, {"annotation": {"kegg.genes": "CELE_B0019.1", "wormbase": "WBGene00000138", "sbo": "SBO:0000243", "uniprot": "Q9XXU5"}, "name": "amx-2", "id": "WBGene00000138"}, {"annotation": {"kegg.genes": "CELE_T03F6.5", "wormbase": "WBGene00003047", "sbo": "SBO:0000243", "uniprot": "Q9NDC9"}, "name": "lis-1", "id": "WBGene00003047"}, {"annotation": {"kegg.genes": "CELE_T01B11.4", "wormbase": "WBGene00020140", "sbo": "SBO:0000243", "uniprot": "G5EFU2"}, "name": "ant-1.4", "id": "WBGene00020140"}, {"annotation": {"kegg.genes": "CELE_H23N18.2", "wormbase": "WBGene00019233", "sbo": "SBO:0000243", "uniprot": "Q9TXZ5"}, "name": "ugt-14", "id": "WBGene00019233"}, {"annotation": {"kegg.genes": "CELE_K08E3.5", "wormbase": "WBGene00010665", "sbo": "SBO:0000243", "uniprot": ["Q9XUS4", "Q9XUS5", "Q9XUS6", "Q8WQE5", "Q86D12", "Q69Z13"]}, "name": "K08E3.5", "id": "WBGene00010665"}, {"annotation": {"kegg.genes": "CELE_Y110A7A.6", "wormbase": "WBGene00022456", "sbo": "SBO:0000243", "uniprot": ["Q95Y85", "Q9N590"]}, "name": "pfkb-1.1", "id": "WBGene00022456"}, {"annotation": {"kegg.genes": "CELE_T27E9.1", "wormbase": "WBGene00006439", "sbo": "SBO:0000243", "uniprot": ["O45865", "G3MU69", "Q86CZ8", "Q86CZ9"]}, "name": "ant-1.1", "id": "WBGene00006439"}, {"annotation": {"kegg.genes": "CELE_W02D3.6", "wormbase": "WBGene00007057", "sbo": "SBO:0000243", "uniprot": "O01813"}, "name": "ant-1.2", "id": "WBGene00007057"}, {"annotation": {"kegg.genes": "CELE_C44H9.1", "wormbase": "WBGene00008097", "sbo": "SBO:0000243", "uniprot": "Q18629"}, "name": "ugt-15", "id": "WBGene00008097"}, {"annotation": {"kegg.genes": "CELE_Y49E10.4", "wormbase": "WBGene00013030", "sbo": "SBO:0000243", "uniprot": "Q9XTU8"}, "name": "Y49E10.4", "id": "WBGene00013030"}, {"annotation": {"kegg.genes": "CELE_W07E6.3", "wormbase": "WBGene00021075", "sbo": "SBO:0000243", "uniprot": "Q9TYV2"}, "name": "W07E6.3", "id": "WBGene00021075"}, {"annotation": {"kegg.genes": "CELE_ZK455.1", "wormbase": "WBGene00000040", "sbo": "SBO:0000243", "uniprot": "Q23500"}, "name": "aco-1", "id": "WBGene00000040"}, {"annotation": {"kegg.genes": "CELE_T12E12.4", "wormbase": "WBGene00001093", "sbo": "SBO:0000243", "uniprot": ["Q8WQC9", "G5EDY8"]}, "name": "drp-1", "id": "WBGene00001093"}, {"annotation": {"kegg.genes": "CELE_R10E11.1", "wormbase": "WBGene00000366", "sbo": "SBO:0000243", "uniprot": "P34545"}, "name": "cbp-1", "id": "WBGene00000366"}, {"annotation": {"kegg.genes": "CELE_C50D2.7", "wormbase": "WBGene00016810", "sbo": "SBO:0000243", "uniprot": "Q86S40"}, "name": "C50D2.7", "id": "WBGene00016810"}, {"annotation": {"kegg.genes": "CELE_C56A3.8", "wormbase": "WBGene00008346", "sbo": "SBO:0000243", "uniprot": ["O45318", "H2L2D3"]}, "name": "C56A3.8", "id": "WBGene00008346"}, {"annotation": {"kegg.genes": "CELE_R09D1.1", "wormbase": "WBGene00011157", "sbo": "SBO:0000243", "uniprot": "Q21857"}, "name": "chil-15", "id": "WBGene00011157"}, {"annotation": {"kegg.genes": "CELE_C05G5.4", "wormbase": "WBGene00007350", "sbo": "SBO:0000243", "uniprot": "P53596"}, "name": "sucl-1", "id": "WBGene00007350"}, {"annotation": {"kegg.genes": "CELE_F23H11.3", "wormbase": "WBGene00017759", "sbo": "SBO:0000243", "uniprot": "O02642"}, "name": "sucl-2", "id": "WBGene00017759"}, {"annotation": {"kegg.genes": "CELE_F52B11.2", "wormbase": "WBGene00009925", "sbo": "SBO:0000243", "uniprot": "Q9XUE6"}, "name": "F52B11.2", "id": "WBGene00009925"}, {"annotation": {"kegg.genes": "CELE_T05H4.4", "wormbase": "WBGene00020267", "sbo": "SBO:0000243", "uniprot": "O16522"}, "name": "T05H4.4", "id": "WBGene00020267"}, {"annotation": {"kegg.genes": "CELE_F54H12.1", "wormbase": "WBGene00000041", "sbo": "SBO:0000243", "uniprot": "P34455"}, "name": "aco-2", "id": "WBGene00000041"}, {"annotation": {"kegg.genes": "CELE_K07A12.3", "wormbase": "WBGene00000209", "sbo": "SBO:0000243", "uniprot": "P90921"}, "name": "asg-1", "id": "WBGene00000209"}, {"annotation": {"kegg.genes": "CELE_C53B7.4", "wormbase": "WBGene00000210", "sbo": "SBO:0000243", "uniprot": "Q18803"}, "name": "asg-2", "id": "WBGene00000210"}, {"annotation": {"kegg.genes": "CELE_C47E12.4", "wormbase": "WBGene00008149", "sbo": "SBO:0000243", "uniprot": "Q18680"}, "name": "pyp-1", "id": "WBGene00008149"}, {"annotation": {"kegg.genes": "CELE_B0024.12", "wormbase": "WBGene00001646", "sbo": "SBO:0000243", "uniprot": "Q17427"}, "name": "gna-1", "id": "WBGene00001646"}, {"annotation": {"kegg.genes": "CELE_F26E4.4", "wormbase": "WBGene00009159", "sbo": "SBO:0000243", "uniprot": "P90847"}, "name": "F26E4.4", "id": "WBGene00009159"}, {"annotation": {"kegg.genes": "CELE_F26E4.6", "wormbase": "WBGene00009161", "sbo": "SBO:0000243", "uniprot": "O18687"}, "name": "F26E4.6", "id": "WBGene00009161"}, {"annotation": {"kegg.genes": "CELE_Y39B6A.3", "wormbase": "WBGene00012666", "sbo": "SBO:0000243", "uniprot": ["Q9NES9", "A5HWB2"]}, "name": "Y39B6A.3", "id": "WBGene00012666"}, {"annotation": {"kegg.genes": "CELE_C02B10.1", "wormbase": "WBGene00015326", "sbo": "SBO:0000243", "uniprot": "G5EEH6"}, "name": "ivd-1", "id": "WBGene00015326"}, {"annotation": {"kegg.genes": "CELE_Y82E9BR.3", "wormbase": "WBGene00022336", "sbo": "SBO:0000243", "uniprot": "Q9BKS0"}, "name": "Y82E9BR.3", "id": "WBGene00022336"}, {"annotation": {"kegg.genes": "CELE_F25B4.6", "wormbase": "WBGene00017769", "sbo": "SBO:0000243", "uniprot": "P54871"}, "name": "hmgs-1", "id": "WBGene00017769"}, {"annotation": {"kegg.genes": "CELE_Y76A2B.5", "wormbase": "WBGene00013577", "sbo": "SBO:0000243", "uniprot": "Q9XWC9"}, "name": "Y76A2B.5", "id": "WBGene00013577"}, {"annotation": {"kegg.genes": "CELE_Y71H2AM.2", "wormbase": "WBGene00022167", "sbo": "SBO:0000243", "uniprot": "Q9BL29"}, "name": "Y71H2AM.2", "id": "WBGene00022167"}, {"annotation": {"kegg.genes": "CELE_K04G7.4", "wormbase": "WBGene00019401", "sbo": "SBO:0000243", "uniprot": ["Q21233", "Q8MQ11"]}, "name": "nuo-4", "id": "WBGene00019401"}, {"annotation": {"kegg.genes": "CELE_Y45G12B.1", "wormbase": "WBGene00021562", "sbo": "SBO:0000243", "uniprot": ["Q9N4Y8", "Q86S77", "Q86S76"]}, "name": "nuo-5", "id": "WBGene00021562"}, {"annotation": {"kegg.genes": "CELE_C47D2.2", "wormbase": "WBGene00000391", "sbo": "SBO:0000243", "uniprot": "Q22922"}, "name": "cdd-1", "id": "WBGene00000391"}, {"annotation": {"kegg.genes": "CELE_C09H10.3", "wormbase": "WBGene00003831", "sbo": "SBO:0000243", "uniprot": "Q17880"}, "name": "nuo-1", "id": "WBGene00003831"}, {"annotation": {"kegg.genes": "CELE_T10E9.7", "wormbase": "WBGene00020417", "sbo": "SBO:0000243", "uniprot": ["O01602", "Q86NC2"]}, "name": "nuo-2", "id": "WBGene00020417"}, {"annotation": {"kegg.genes": "CELE_Y57G11C.12", "wormbase": "WBGene00013308", "sbo": "SBO:0000243", "uniprot": ["O18236", "A5Z2X2"]}, "name": "nuo-3", "id": "WBGene00013308"}, {"annotation": {"kegg.genes": "CELE_Y23H5A.7", "wormbase": "WBGene00000800", "sbo": "SBO:0000243", "uniprot": ["Q965I6", "O76618"]}, "name": "cars-1", "id": "WBGene00000800"}, {"annotation": {"kegg.genes": "CELE_Y47D9A.1", "wormbase": "WBGene00021628", "sbo": "SBO:0000243", "uniprot": ["Q9N4V2", "Q9N4V3"]}, "name": "Y47D9A.1", "id": "WBGene00021628"}, {"annotation": {"kegg.genes": "CELE_M01F1.1", "wormbase": "WBGene00001639", "sbo": "SBO:0000243", "uniprot": "G5EFK6"}, "name": "gly-14", "id": "WBGene00001639"}, {"annotation": {"kegg.genes": "CELE_B0348.4", "wormbase": "WBGene00001177", "sbo": "SBO:0000243", "uniprot": "G5EBH0"}, "name": "egl-8", "id": "WBGene00001177"}, {"annotation": {"kegg.genes": "CELE_F39B2.3", "wormbase": "WBGene00009554", "sbo": "SBO:0000243", "uniprot": "O45496"}, "name": "F39B2.3", "id": "WBGene00009554"}, {"annotation": {"kegg.genes": "CELE_E02H1.4", "wormbase": "WBGene00004050", "sbo": "SBO:0000243", "uniprot": "Q09525"}, "name": "parp-2", "id": "WBGene00004050"}, {"annotation": {"kegg.genes": "CELE_K02A4.1", "wormbase": "WBGene00001149", "sbo": "SBO:0000243", "uniprot": "P54688"}, "name": "bcat-1", "id": "WBGene00001149"}, {"annotation": {"kegg.genes": "CELE_ZK973.11", "wormbase": "WBGene00022836", "sbo": "SBO:0000243", "uniprot": "Q9N4L6"}, "name": "ZK973.11", "id": "WBGene00022836"}, {"annotation": {"kegg.genes": "CELE_ZC395.10", "wormbase": "WBGene00022599", "sbo": "SBO:0000243", "uniprot": "Q23280"}, "name": "ZC395.10", "id": "WBGene00022599"}, {"annotation": {"kegg.genes": "CELE_B0035.5", "wormbase": "WBGene00007108", "sbo": "SBO:0000243", "uniprot": "Q27464"}, "name": "gspd-1", "id": "WBGene00007108"}, {"annotation": {"kegg.genes": "CELE_ZK637.8", "wormbase": "WBGene00006768", "sbo": "SBO:0000243", "uniprot": "P30628"}, "name": "unc-32", "id": "WBGene00006768"}, {"annotation": {"kegg.genes": "CELE_Y51H4A.7", "wormbase": "WBGene00013103", "sbo": "SBO:0000243", "uniprot": "Q9NAE2"}, "name": "Y51H4A.7", "id": "WBGene00013103"}, {"annotation": {"kegg.genes": "CELE_F08G5.2", "wormbase": "WBGene00008581", "sbo": "SBO:0000243", "uniprot": "Q19221"}, "name": "acl-13", "id": "WBGene00008581"}, {"annotation": {"kegg.genes": "CELE_Y48A6B.9", "wormbase": "WBGene00012970", "sbo": "SBO:0000243", "uniprot": ["F3Y5Q6", "Q9XXC8"]}, "name": "Y48A6B.9", "id": "WBGene00012970"}, {"annotation": {"kegg.genes": "CELE_R01H2.5", "wormbase": "WBGene00019813", "sbo": "SBO:0000243", "uniprot": "G5EER4"}, "name": "ger-1", "id": "WBGene00019813"}, {"annotation": {"kegg.genes": "CELE_H43I07.2", "wormbase": "WBGene00019275", "sbo": "SBO:0000243", "uniprot": "Q9UAY9"}, "name": "rpac-40", "id": "WBGene00019275"}, {"annotation": {"kegg.genes": "CELE_T27F6.5", "wormbase": "WBGene00004190", "sbo": "SBO:0000243", "uniprot": ["A5JYY0", "Q1ZXS0", "Q1ZXR9", "O45869"]}, "name": "pars-2", "id": "WBGene00004190"}, {"annotation": {"kegg.genes": "CELE_Y66D12A.7", "wormbase": "WBGene00013433", "sbo": "SBO:0000243", "uniprot": "Q9BI40"}, "name": "Y66D12A.7", "id": "WBGene00013433"}, {"annotation": {"kegg.genes": "CELE_F22D6.4", "wormbase": "WBGene00009051", "sbo": "SBO:0000243", "uniprot": "Q19724"}, "name": "nduf-6", "id": "WBGene00009051"}, {"annotation": {"kegg.genes": ["CELE_Y60A3A.13", "CELE_Y60A3A.13a"], "wormbase": "WBGene00013361", "sbo": "SBO:0000243", "uniprot": ["B1V8K6", "G5ECI8", "G5EEN1"]}, "name": "fars-2", "id": "WBGene00013361"}, {"annotation": {"kegg.genes": "CELE_Y54E10BL.5", "wormbase": "WBGene00021839", "sbo": "SBO:0000243", "uniprot": "Q9N3D9"}, "name": "nduf-5", "id": "WBGene00021839"}, {"annotation": {"kegg.genes": "CELE_C05D11.11", "wormbase": "WBGene00003214", "sbo": "SBO:0000243", "uniprot": "P50432"}, "name": "mel-32", "id": "WBGene00003214"}, {"annotation": {"kegg.genes": "CELE_C42D8.3", "wormbase": "WBGene00006862", "sbo": "SBO:0000243", "uniprot": "Q18580"}, "name": "pnk-4", "id": "WBGene00006862"}, {"annotation": {"kegg.genes": "CELE_T23G5.1", "wormbase": "WBGene00004391", "sbo": "SBO:0000243", "uniprot": "Q03604"}, "name": "rnr-1", "id": "WBGene00004391"}, {"annotation": {"kegg.genes": "CELE_C47E12.1", "wormbase": "WBGene00005663", "sbo": "SBO:0000243", "uniprot": "Q18678"}, "name": "sars-1", "id": "WBGene00005663"}, {"annotation": {"kegg.genes": "CELE_Y57G11C.3", "wormbase": "WBGene00013301", "sbo": "SBO:0000243", "uniprot": "O18229"}, "name": "Y57G11C.3", "id": "WBGene00013301"}, {"annotation": {"kegg.genes": "CELE_F53C11.3", "wormbase": "WBGene00009973", "sbo": "SBO:0000243", "uniprot": "Q93761"}, "name": "F53C11.3", "id": "WBGene00009973"}, {"annotation": {"kegg.genes": "CELE_Y56A3A.3", "wormbase": "WBGene00003234", "sbo": "SBO:0000243", "uniprot": "Q9U228"}, "name": "mif-1", "id": "WBGene00003234"}, {"annotation": {"kegg.genes": "CELE_C24A3.4", "wormbase": "WBGene00016034", "sbo": "SBO:0000243", "uniprot": "Q18122"}, "name": "C24A3.4", "id": "WBGene00016034"}, {"annotation": {"kegg.genes": "CELE_ZC373.5", "wormbase": "WBGene00013870", "sbo": "SBO:0000243", "uniprot": "Q23261"}, "name": "ZC373.5", "id": "WBGene00013870"}, {"annotation": {"kegg.genes": "CELE_F38B2.4", "wormbase": "WBGene00009531", "sbo": "SBO:0000243", "uniprot": "Q20140"}, "name": "F38B2.4", "id": "WBGene00009531"}, {"annotation": {"kegg.genes": "CELE_W06H3.2", "wormbase": "WBGene00004248", "sbo": "SBO:0000243", "uniprot": ["Q9XXN0", "B1V8I7"]}, "name": "pus-1", "id": "WBGene00004248"}, {"annotation": {"kegg.genes": "CELE_T01C4.1", "wormbase": "WBGene00020141", "sbo": "SBO:0000243", "uniprot": "Q94298"}, "name": "lmd-5", "id": "WBGene00020141"}, {"annotation": {"kegg.genes": "CELE_C56G2.6", "wormbase": "WBGene00002891", "sbo": "SBO:0000243", "uniprot": ["Q09517", "C1P622"]}, "name": "let-767", "id": "WBGene00002891"}, {"annotation": {"kegg.genes": "ND5", "wormbase": "WBGene00010967", "sbo": "SBO:0000243", "uniprot": "P24896"}, "name": "nduo-5", "id": "WBGene00010967"}, {"annotation": {"kegg.genes": "CELE_F25H5.3", "wormbase": "WBGene00009126", "sbo": "SBO:0000243", "uniprot": ["O17836", "B7WNA0", "O17835", "Q7JL40", "Q3S1I8"]}, "name": "pyk-1", "id": "WBGene00009126"}, {"annotation": {"kegg.genes": "ND3", "wormbase": "WBGene00010966", "sbo": "SBO:0000243", "uniprot": ["G5EDH4", "P24895"]}, "name": "nduo-3", "id": "WBGene00010966"}, {"annotation": {"kegg.genes": "CELE_F35G12.10", "wormbase": "WBGene00000206", "sbo": "SBO:0000243", "uniprot": "Q20053"}, "name": "asb-1", "id": "WBGene00000206"}, {"annotation": {"kegg.genes": "CELE_F02E8.1", "wormbase": "WBGene00000207", "sbo": "SBO:0000243", "uniprot": "Q19126"}, "name": "asb-2", "id": "WBGene00000207"}, {"annotation": {"kegg.genes": "CELE_Y52B11C.1", "wormbase": "WBGene00013131", "sbo": "SBO:0000243", "uniprot": "D4YWC2"}, "name": "Y52B11C.1", "id": "WBGene00013131"}, {"annotation": {"kegg.genes": "CELE_Y71H2AM.6", "wormbase": "WBGene00022171", "sbo": "SBO:0000243", "uniprot": ["Q9BL36", "B5D5N5"]}, "name": "Y71H2AM.6", "id": "WBGene00022171"}, {"annotation": {"kegg.genes": "CELE_W02F12.2", "wormbase": "WBGene00020947", "sbo": "SBO:0000243", "uniprot": "O45145"}, "name": "W02F12.2", "id": "WBGene00020947"}, {"annotation": {"kegg.genes": "CELE_Y71H2AM.4", "wormbase": "WBGene00022169", "sbo": "SBO:0000243", "uniprot": "Q9BL33"}, "name": "Y71H2AM.4", "id": "WBGene00022169"}, {"annotation": {"kegg.genes": "CELE_Y43F4A.4", "wormbase": "WBGene00012799", "sbo": "SBO:0000243", "uniprot": "O45930"}, "name": "Y43F4A.4", "id": "WBGene00012799"}, {"annotation": {"kegg.genes": "CELE_B0240.3", "wormbase": "WBGene00000907", "sbo": "SBO:0000243", "uniprot": "Q8I4N4"}, "name": "daf-11", "id": "WBGene00000907"}, {"annotation": {"kegg.genes": "CELE_Y46G5A.2", "wormbase": "WBGene00012895", "sbo": "SBO:0000243", "uniprot": "K8ES01"}, "name": "cox-10", "id": "WBGene00012895"}, {"annotation": {"kegg.genes": "CELE_K09H11.7", "wormbase": "WBGene00019604", "sbo": "SBO:0000243", "uniprot": "O01591"}, "name": "K09H11.7", "id": "WBGene00019604"}, {"annotation": {"kegg.genes": "CELE_F19H8.1", "wormbase": "WBGene00006603", "sbo": "SBO:0000243", "uniprot": "O45380"}, "name": "tps-2", "id": "WBGene00006603"}, {"annotation": {"kegg.genes": "CELE_B0303.3", "wormbase": "WBGene00015125", "sbo": "SBO:0000243", "uniprot": "P34255"}, "name": "B0303.3", "id": "WBGene00015125"}, {"annotation": {"kegg.genes": "CELE_B0286.3", "wormbase": "WBGene00015116", "sbo": "SBO:0000243", "uniprot": "Q10457"}, "name": "pacs-1", "id": "WBGene00015116"}, {"annotation": {"kegg.genes": "CELE_Y22D7AL.14", "wormbase": "WBGene00021252", "sbo": "SBO:0000243", "uniprot": "Q965P2"}, "name": "cht-4", "id": "WBGene00021252"}, {"annotation": {"kegg.genes": "CELE_F45H10.1", "wormbase": "WBGene00000113", "sbo": "SBO:0000243", "uniprot": ["G3MU66", "O02266"]}, "name": "alh-7", "id": "WBGene00000113"}, {"annotation": {"kegg.genes": "CELE_F38B6.4", "wormbase": "WBGene00018174", "sbo": "SBO:0000243", "uniprot": "Q20143"}, "name": "F38B6.4", "id": "WBGene00018174"}, {"annotation": {"kegg.genes": "CELE_C45E5.2", "wormbase": "WBGene00016665", "sbo": "SBO:0000243"}, "name": "chil-11", "id": "WBGene00016665"}, {"annotation": {"kegg.genes": "CELE_F52E1.10", "wormbase": "WBGene00018698", "sbo": "SBO:0000243", "uniprot": "Q20666"}, "name": "vha-18", "id": "WBGene00018698"}, {"annotation": {"kegg.genes": "CELE_ZK430.2", "wormbase": "WBGene00044063", "sbo": "SBO:0000243", "uniprot": "Q23493"}, "name": "bpnt-1", "id": "WBGene00044063"}, {"annotation": {"kegg.genes": "CELE_F13D12.2", "wormbase": "WBGene00002262", "sbo": "SBO:0000243", "uniprot": "Q27888"}, "name": "ldh-1", "id": "WBGene00002262"}, {"annotation": {"kegg.genes": "CELE_F32D1.5", "wormbase": "WBGene00017984", "sbo": "SBO:0000243", "uniprot": "O16294"}, "name": "F32D1.5", "id": "WBGene00017984"}, {"annotation": {"kegg.genes": "CELE_Y17G7B.3", "wormbase": "WBGene00012459", "sbo": "SBO:0000243", "uniprot": "Q9XXJ1"}, "name": "Y17G7B.3", "id": "WBGene00012459"}, {"annotation": {"kegg.genes": "CELE_T10B11.1", "wormbase": "WBGene00020397", "sbo": "SBO:0000243", "uniprot": "Q9TZH6"}, "name": "pcbd-1", "id": "WBGene00020397"}, {"annotation": {"kegg.genes": "CELE_C13C4.4", "wormbase": "WBGene00007548", "sbo": "SBO:0000243", "uniprot": "O01926"}, "name": "C13C4.4", "id": "WBGene00007548"}, {"annotation": {"kegg.genes": "CELE_T22G5.1", "wormbase": "WBGene00011929", "sbo": "SBO:0000243", "uniprot": "O02322"}, "name": "T22G5.1", "id": "WBGene00011929"}, {"annotation": {"kegg.genes": "CELE_F55G1.9", "wormbase": "WBGene00018904", "sbo": "SBO:0000243", "uniprot": "Q20848"}, "name": "F55G1.9", "id": "WBGene00018904"}, {"annotation": {"kegg.genes": "CELE_C05C8.7", "wormbase": "WBGene00015464", "sbo": "SBO:0000243", "uniprot": "O16315"}, "name": "C05C8.7", "id": "WBGene00015464"}, {"annotation": {"kegg.genes": "CELE_M106.4", "wormbase": "WBGene00010912", "sbo": "SBO:0000243", "uniprot": "Q09580"}, "name": "gmps-1", "id": "WBGene00010912"}, {"annotation": {"kegg.genes": "CELE_Y105E8B.5", "wormbase": "WBGene00013690", "sbo": "SBO:0000243", "uniprot": "Q9NF11"}, "name": "hprt-1", "id": "WBGene00013690"}, {"annotation": {"kegg.genes": "CELE_W10D5.2", "wormbase": "WBGene00012376", "sbo": "SBO:0000243", "uniprot": "Q94360"}, "name": "nduf-7", "id": "WBGene00012376"}, {"annotation": {"kegg.genes": "CELE_F14B4.3", "wormbase": "WBGene00008781", "sbo": "SBO:0000243", "uniprot": "Q27493"}, "name": "rpoa-2", "id": "WBGene00008781"}, {"annotation": {"kegg.genes": "CELE_T25B9.10", "wormbase": "WBGene00012016", "sbo": "SBO:0000243", "uniprot": ["G5EBY9", "G5EGN9"]}, "name": "inpp-1", "id": "WBGene00012016"}, {"annotation": {"kegg.genes": "CELE_D1054.13", "wormbase": "WBGene00008379", "sbo": "SBO:0000243", "uniprot": "Q18953"}, "name": "secs-1", "id": "WBGene00008379"}, {"annotation": {"kegg.genes": "CELE_T13H5.3", "wormbase": "WBGene00011757", "sbo": "SBO:0000243", "uniprot": "Q22468"}, "name": "cht-2", "id": "WBGene00011757"}, {"annotation": {"kegg.genes": "CELE_Y57A10C.6", "wormbase": "WBGene00013284", "sbo": "SBO:0000243", "uniprot": "G5EDP2"}, "name": "daf-22", "id": "WBGene00013284"}, {"annotation": {"kegg.genes": "CELE_Y48E1A.1", "wormbase": "WBGene00012999", "sbo": "SBO:0000243", "uniprot": ["G5EDG7", "G5ED21"]}, "name": "rpoa-1", "id": "WBGene00012999"}, {"annotation": {"kegg.genes": "CELE_C03C10.3", "wormbase": "WBGene00004392", "sbo": "SBO:0000243", "uniprot": "P42170"}, "name": "rnr-2", "id": "WBGene00004392"}, {"annotation": {"kegg.genes": "CELE_W06B3.1", "wormbase": "WBGene00012295", "sbo": "SBO:0000243", "uniprot": "Q9XXM2"}, "name": "nmat-1", "id": "WBGene00012295"}, {"annotation": {"kegg.genes": "CELE_R04B3.2", "wormbase": "WBGene00019867", "sbo": "SBO:0000243", "uniprot": "Q21697"}, "name": "R04B3.2", "id": "WBGene00019867"}, {"annotation": {"kegg.genes": "CELE_Y55B1AL.3", "wormbase": "WBGene00021905", "sbo": "SBO:0000243", "uniprot": ["Q65XX0", "H2KY86"]}, "name": "helq-1", "id": "WBGene00021905"}, {"annotation": {"kegg.genes": "CELE_B0272.4", "wormbase": "WBGene00007130", "sbo": "SBO:0000243", "uniprot": "P41942"}, "name": "B0272.4", "id": "WBGene00007130"}, {"annotation": {"kegg.genes": "CELE_Y105C5B.3", "wormbase": "WBGene00013646", "sbo": "SBO:0000243", "uniprot": "Q9NAM9"}, "name": "Y105C5B.3", "id": "WBGene00013646"}, {"annotation": {"kegg.genes": "CELE_B0272.3", "wormbase": "WBGene00007129", "sbo": "SBO:0000243", "uniprot": "P41938"}, "name": "B0272.3", "id": "WBGene00007129"}, {"annotation": {"kegg.genes": "CELE_Y71H10B.1", "wormbase": "WBGene00022201", "sbo": "SBO:0000243", "uniprot": ["Q9TZC8", "Q95X21", "Q86MI3"]}, "name": "Y71H10B.1", "id": "WBGene00022201"}, {"annotation": {"kegg.genes": "CELE_F13H8.7", "wormbase": "WBGene00017440", "sbo": "SBO:0000243", "uniprot": "Q19437"}, "name": "upb-1", "id": "WBGene00017440"}, {"annotation": {"kegg.genes": "CELE_R09B5.6", "wormbase": "WBGene00019978", "sbo": "SBO:0000243", "uniprot": "O44608"}, "name": "hacd-1", "id": "WBGene00019978"}, {"annotation": {"kegg.genes": "CELE_C09B8.1", "wormbase": "WBGene00002146", "sbo": "SBO:0000243", "uniprot": "Q17848"}, "name": "ipp-5", "id": "WBGene00002146"}, {"annotation": {"kegg.genes": "CELE_C01B4.6", "wormbase": "WBGene00015270", "sbo": "SBO:0000243", "uniprot": "G5ECR6"}, "name": "C01B4.6", "id": "WBGene00015270"}, {"annotation": {"kegg.genes": "CELE_K08F11.4", "wormbase": "WBGene00006968", "sbo": "SBO:0000243", "uniprot": ["H2KZL6", "Q8MPU1"]}, "name": "yars-2", "id": "WBGene00006968"}, {"annotation": {"kegg.genes": "CELE_C16C10.10", "wormbase": "WBGene00006448", "sbo": "SBO:0000243", "uniprot": "Q09253"}, "name": "glod-4", "id": "WBGene00006448"}, {"annotation": {"kegg.genes": "CELE_R09D1.3", "wormbase": "WBGene00011159", "sbo": "SBO:0000243", "uniprot": "Q21859"}, "name": "chil-17", "id": "WBGene00011159"}, {"annotation": {"kegg.genes": "CELE_Y105E8A.19", "wormbase": "WBGene00013677", "sbo": "SBO:0000243", "uniprot": "G5ED95"}, "name": "yars-1", "id": "WBGene00013677"}, {"annotation": {"kegg.genes": "CELE_T22H6.2", "wormbase": "WBGene00011938", "sbo": "SBO:0000243", "uniprot": "P54889"}, "name": "alh-13", "id": "WBGene00011938"}, {"annotation": {"kegg.genes": "CELE_R04B5.5", "wormbase": "WBGene00011003", "sbo": "SBO:0000243", "uniprot": "Q21702"}, "name": "R04B5.5", "id": "WBGene00011003"}, {"annotation": {"kegg.genes": "CELE_R04B5.6", "wormbase": "WBGene00011004", "sbo": "SBO:0000243", "uniprot": "Q21703"}, "name": "R04B5.6", "id": "WBGene00011004"}, {"annotation": {"kegg.genes": "CELE_C45B2.5", "wormbase": "WBGene00001602", "sbo": "SBO:0000243", "uniprot": "Q95YD1"}, "name": "gln-1", "id": "WBGene00001602"}, {"annotation": {"kegg.genes": "CELE_Y53F4B.3", "wormbase": "WBGene00013150", "sbo": "SBO:0000243", "uniprot": "Q9NAC5"}, "name": "Y53F4B.3", "id": "WBGene00013150"}, {"annotation": {"kegg.genes": "CELE_F43H9.1", "wormbase": "WBGene00001152", "sbo": "SBO:0000243", "uniprot": "Q20376"}, "name": "ech-3", "id": "WBGene00001152"}, {"annotation": {"kegg.genes": "CELE_Y32F6A.3", "wormbase": "WBGene00012528", "sbo": "SBO:0000243", "uniprot": "Q9U2P3"}, "name": "pap-1", "id": "WBGene00012528"}, {"annotation": {"kegg.genes": "CELE_T05H10.6", "wormbase": "WBGene00011510", "sbo": "SBO:0000243", "uniprot": ["Q8I111", "P52899"]}, "name": "pdha-1", "id": "WBGene00011510"}, {"annotation": {"kegg.genes": "CELE_Y42G9A.4", "wormbase": "WBGene00021534", "sbo": "SBO:0000243", "uniprot": ["Q65XX8", "Q65XX9", "Q9N4Z7", "Q65XY0"]}, "name": "mvk-1", "id": "WBGene00021534"}, {"annotation": {"kegg.genes": "CELE_F54D8.2", "wormbase": "WBGene00006519", "sbo": "SBO:0000243", "uniprot": "Q20779"}, "name": "tag-174", "id": "WBGene00006519"}, {"annotation": {"kegg.genes": "CELE_F13G3.5", "wormbase": "WBGene00008765", "sbo": "SBO:0000243", "uniprot": "Q19420"}, "name": "ttx-7", "id": "WBGene00008765"}, {"annotation": {"kegg.genes": "CELE_Y110A7A.12", "wormbase": "WBGene00004959", "sbo": "SBO:0000243", "uniprot": "Q9N5A0"}, "name": "spe-5", "id": "WBGene00004959"}, {"annotation": {"kegg.genes": "CELE_C26E6.4", "wormbase": "WBGene00016140", "sbo": "SBO:0000243", "uniprot": "Q10578"}, "name": "rpb-2", "id": "WBGene00016140"}, {"annotation": {"kegg.genes": "CELE_F21F3.3", "wormbase": "WBGene00017673", "sbo": "SBO:0000243", "uniprot": "P91266"}, "name": "icmt-1", "id": "WBGene00017673"}, {"annotation": {"kegg.genes": "CELE_T14F9.1", "wormbase": "WBGene00020507", "sbo": "SBO:0000243", "uniprot": "Q22494"}, "name": "vha-15", "id": "WBGene00020507"}, {"annotation": {"kegg.genes": "CELE_W03A3.2", "wormbase": "WBGene00020964", "sbo": "SBO:0000243", "uniprot": "A0FLQ6"}, "name": "polq-1", "id": "WBGene00020964"}, {"annotation": {"kegg.genes": "CELE_Y95B8A.10", "wormbase": "WBGene00022389", "sbo": "SBO:0000243", "uniprot": ["G8JYF6", "Q9N2V9"]}, "name": "pde-6", "id": "WBGene00022389"}, {"annotation": {"kegg.genes": "CELE_R01H10.1", "wormbase": "WBGene00001002", "sbo": "SBO:0000243", "uniprot": "Q21625"}, "name": "div-1", "id": "WBGene00001002"}, {"annotation": {"kegg.genes": "CELE_F55F3.3", "wormbase": "WBGene00010117", "sbo": "SBO:0000243", "uniprot": "Q9XUY5"}, "name": "nkb-3", "id": "WBGene00010117"}, {"annotation": {"kegg.genes": "CELE_T02G5.8", "wormbase": "WBGene00002183", "sbo": "SBO:0000243", "uniprot": "Q22100"}, "name": "kat-1", "id": "WBGene00002183"}, {"annotation": {"kegg.genes": "CELE_D2023.4", "wormbase": "WBGene00008408", "sbo": "SBO:0000243", "uniprot": "O17731"}, "name": "D2023.4", "id": "WBGene00008408"}, {"annotation": {"kegg.genes": "CELE_F08F3.2", "wormbase": "WBGene00017261", "sbo": "SBO:0000243", "uniprot": ["Q22949", "G8JY39"]}, "name": "acl-6", "id": "WBGene00017261"}, {"annotation": {"kegg.genes": "CELE_ZC443.5", "wormbase": "WBGene00013900", "sbo": "SBO:0000243", "uniprot": "Q23323"}, "name": "ugt-18", "id": "WBGene00013900"}, {"annotation": {"kegg.genes": "CELE_C14A4.3", "wormbase": "WBGene00007556", "sbo": "SBO:0000243", "uniprot": "P54002"}, "name": "C14A4.3", "id": "WBGene00007556"}, {"annotation": {"kegg.genes": "CELE_T26A5.4", "wormbase": "WBGene00020820", "sbo": "SBO:0000243", "uniprot": "Q22797"}, "name": "algn-1", "id": "WBGene00020820"}, {"annotation": {"kegg.genes": "CELE_C50F4.2", "wormbase": "WBGene00008230", "sbo": "SBO:0000243", "uniprot": "Q27483"}, "name": "pfk-1.2", "id": "WBGene00008230"}, {"annotation": {"kegg.genes": "CELE_R08D7.6", "wormbase": "WBGene00011146", "sbo": "SBO:0000243", "uniprot": "P30645"}, "name": "pde-2", "id": "WBGene00011146"}, {"annotation": {"kegg.genes": "CELE_F30F8.2", "wormbase": "WBGene00009271", "sbo": "SBO:0000243", "uniprot": "Q93650"}, "name": "glna-3", "id": "WBGene00009271"}, {"annotation": {"kegg.genes": "CELE_DH11.1", "wormbase": "WBGene00008435", "sbo": "SBO:0000243", "uniprot": "Q19013"}, "name": "glna-2", "id": "WBGene00008435"}, {"annotation": {"kegg.genes": "CELE_C09F9.3", "wormbase": "WBGene00007480", "sbo": "SBO:0000243", "uniprot": ["H2L2H2", "H2L2H3", "B0M0P0", "B0M0N9", "B6VQ90"]}, "name": "glna-1", "id": "WBGene00007480"}, {"annotation": {"kegg.genes": "CELE_Y38C1AA.11", "wormbase": "WBGene00021401", "sbo": "SBO:0000243", "uniprot": "Q8MXT1"}, "name": "prdx-6", "id": "WBGene00021401"}, {"annotation": {"kegg.genes": "CELE_F43E2.2", "wormbase": "WBGene00018391", "sbo": "SBO:0000243", "uniprot": "O02092"}, "name": "rpb-4", "id": "WBGene00018391"}, {"annotation": {"kegg.genes": "CELE_K03H1.13", "wormbase": "WBGene00044903", "sbo": "SBO:0000243", "uniprot": ["Q0PDK5", "F5GU77"]}, "name": "K03H1.13", "id": "WBGene00044903"}, {"annotation": {"kegg.genes": "CELE_K04D7.3", "wormbase": "WBGene00001794", "sbo": "SBO:0000243", "uniprot": "Q21217"}, "name": "gta-1", "id": "WBGene00001794"}, {"annotation": {"kegg.genes": "CELE_C18E9.4", "wormbase": "WBGene00007684", "sbo": "SBO:0000243", "uniprot": "Q18095"}, "name": "C18E9.4", "id": "WBGene00007684"}, {"annotation": {"kegg.genes": "CELE_C04F6.3", "wormbase": "WBGene00000503", "sbo": "SBO:0000243", "uniprot": "Q11174"}, "name": "cht-1", "id": "WBGene00000503"}, {"annotation": {"kegg.genes": "CELE_T07C4.1", "wormbase": "WBGene00011559", "sbo": "SBO:0000243", "uniprot": "G5EDZ2"}, "name": "umps-1", "id": "WBGene00011559"}, {"annotation": {"kegg.genes": "CELE_T01B11.2", "wormbase": "WBGene00020139", "sbo": "SBO:0000243", "uniprot": "P91408"}, "name": "T01B11.2", "id": "WBGene00020139"}, {"annotation": {"kegg.genes": "CELE_R74.1", "wormbase": "WBGene00003073", "sbo": "SBO:0000243", "uniprot": "Q09996"}, "name": "lars-1", "id": "WBGene00003073"}, {"annotation": {"kegg.genes": "CELE_F42A9.1", "wormbase": "WBGene00006483", "sbo": "SBO:0000243", "uniprot": ["D5MCN8", "H2KZC9"]}, "name": "dgk-4", "id": "WBGene00006483"}, {"annotation": {"kegg.genes": "CELE_F22F7.5", "wormbase": "WBGene00000514", "sbo": "SBO:0000243", "uniprot": "Q9GZF3"}, "name": "ckb-4", "id": "WBGene00000514"}, {"annotation": {"kegg.genes": "CELE_B0285.9", "wormbase": "WBGene00000512", "sbo": "SBO:0000243", "uniprot": "P46559"}, "name": "ckb-2", "id": "WBGene00000512"}, {"annotation": {"kegg.genes": "CELE_B0285.10", "wormbase": "WBGene00000513", "sbo": "SBO:0000243", "uniprot": "P46560"}, "name": "ckb-3", "id": "WBGene00000513"}, {"annotation": {"kegg.genes": "CELE_C17C3.3", "wormbase": "WBGene00015889", "sbo": "SBO:0000243", "uniprot": "Q18061"}, "name": "C17C3.3", "id": "WBGene00015889"}, {"annotation": {"kegg.genes": "CELE_B0285.8", "wormbase": "WBGene00000511", "sbo": "SBO:0000243", "uniprot": "P46558"}, "name": "ckb-1", "id": "WBGene00000511"}, {"annotation": {"kegg.genes": "CELE_C09G4.1", "wormbase": "WBGene00002043", "sbo": "SBO:0000243", "uniprot": "G5ED45"}, "name": "hyl-1", "id": "WBGene00002043"}, {"annotation": {"kegg.genes": "CELE_F32B5.1", "wormbase": "WBGene00017975", "sbo": "SBO:0000243", "uniprot": "O01854"}, "name": "F32B5.1", "id": "WBGene00017975"}, {"annotation": {"kegg.genes": "CELE_C06A8.1", "wormbase": "WBGene00015512", "sbo": "SBO:0000243", "uniprot": ["G8JXY2", "Q17693"]}, "name": "mthf-1", "id": "WBGene00015512"}, {"annotation": {"kegg.genes": "CELE_F56H11.4", "wormbase": "WBGene00001239", "sbo": "SBO:0000243", "uniprot": "G5EEE5"}, "name": "elo-1", "id": "WBGene00001239"}], "compartments": {"m": "mitochondria", "c": "cytosol", "e": "extracellular space"}, "metabolites": [{"charge": -1, "name": "5-Methyltetrahydrofolate", "formula": "C20H24N7O6", "compartment": "e", "id": "5mthf_e", "annotation": {"bigg.metabolite": "5mthf", "sbo": "SBO:0000247", "kegg.compound": "C00440"}}, {"charge": 1, "name": "Thiamin", "formula": "C12H17N4OS", "compartment": "m", "id": "thm_m", "annotation": {"bigg.metabolite": "thm", "sbo": "SBO:0000247", "kegg.compound": "C00378"}}, {"charge": 0, "name": "Protein C-terminal S-farnesyl-L-cysteine ", "formula": "C20H33N2O3SR(C2H2NOR)n", "compartment": "c", "id": "protSfarC_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C04506"}}, {"charge": -1, "name": "Thiocyanate", "formula": "CNS", "compartment": "c", "id": "tcynt_c", "annotation": {"bigg.metabolite": "tcynt", "sbo": "SBO:0000247", "kegg.compound": "C01755"}}, {"charge": -1, "name": "Bicarbonate", "formula": "CHO3", "compartment": "e", "id": "hco3_e", "annotation": {"bigg.metabolite": "hco3", "sbo": "SBO:0000247", "kegg.compound": "C00288"}}, {"charge": -2, "name": "N-Acetyl-D-glucosaminyldiphosphodolichol", "formula": "C118H193NO12P2", "compartment": "c", "id": "naglc2p_c", "annotation": {"bigg.metabolite": ["naglc2p_L", "naglc2p_U"], "sbo": "SBO:0000247", "kegg.compound": "C04500"}}, {"charge": -2, "name": "N-Acetyl-D-glucosamine 1-phosphate", "formula": "C8H14NO9P", "compartment": "c", "id": "acgam1p_c", "annotation": {"bigg.metabolite": "acgam1p", "sbo": "SBO:0000247", "kegg.compound": "C04501"}}, {"charge": 0, "name": "Dihydroneopterin", "formula": "C9H13N5O4", "compartment": "c", "id": "dhnpt_c", "annotation": {"bigg.metabolite": "dhnpt", "sbo": "SBO:0000247", "kegg.compound": "C04874"}}, {"charge": 0, "name": "9-cis-retinol", "formula": "C20H30O", "compartment": "c", "id": "retinol-9-cis_c", "annotation": {"bigg.metabolite": "retinol-9-cis", "sbo": "SBO:0000247", "kegg.compound": "C16682"}}, {"charge": 0, "name": "cis-9-retinal", "formula": "C20H28O", "compartment": "c", "id": "retinal-cis-9_c", "annotation": {"bigg.metabolite": "retinal-cis-9", "sbo": "SBO:0000247", "kegg.compound": "C16681"}}, {"charge": -1, "name": "Ascaroside 1", "formula": "C13H23O6", "compartment": "c", "id": "ascr1_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -1, "name": "Ascaroside 10", "formula": "C15H27O6", "compartment": "c", "id": "ascr10_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -1, "name": "Ascaroside 5", "formula": "C9H15O6", "compartment": "c", "id": "ascr5_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 0, "name": "Stearoylcarnitine", "formula": "C25H49NO4", "compartment": "m", "id": "stcrn_m", "annotation": {"bigg.metabolite": "stcrn", "sbo": "SBO:0000247"}}, {"charge": -4, "name": "ascaryl (ascr5) coa", "formula": "C30H46N7O21P3S", "compartment": "c", "id": "ascr5coa_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -4, "name": "octacosanoyl-CoA", "formula": "C49H86N7O17P3S", "compartment": "c", "id": "fa28p0coa_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 0, "name": "trans-4-Hydroxy-L-proline", "formula": "C5H9NO3", "compartment": "m", "id": "4hpro-LT_m", "annotation": {"bigg.metabolite": "4hpro-LT", "sbo": "SBO:0000247", "kegg.compound": "C01157"}}, {"charge": 0, "name": "dihomo-gamma-linolenyl carnitine", "formula": "C27H47NO4", "compartment": "m", "id": "dlnlcgcrn_m", "annotation": {"bigg.metabolite": "dlnlcgcrn", "sbo": "SBO:0000247"}}, {"charge": 0, "name": "Linoleyl carnitine", "formula": "C25H45NO4", "compartment": "m", "id": "lnlccrn_m", "annotation": {"bigg.metabolite": "lnlccrn", "sbo": "SBO:0000247"}}, {"charge": -4, "name": "ascaryl (ascr7) coa", "formula": "C34H52N7O21P3S", "compartment": "c", "id": "ascr7coa_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -4, "name": "ascaryl (ascr3) coa", "formula": "C36H56N7O21P3S", "compartment": "c", "id": "ascr3coa_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 0, "name": "C20:4 carnitine", "formula": "C27H45NO4", "compartment": "m", "id": "arachdcrn_m", "annotation": {"bigg.metabolite": "arachdcrn", "sbo": "SBO:0000247"}}, {"charge": 0, "name": "Eicosatetranoyl carnitine", "formula": "C27H45NO4", "compartment": "m", "id": "eicostetcrn_m", "annotation": {"bigg.metabolite": "eicostetcrn", "sbo": "SBO:0000247"}}, {"charge": 0, "name": "Timnodonyl carnitine", "formula": "C27H43NO4", "compartment": "m", "id": "tmndnccrn_m", "annotation": {"bigg.metabolite": "tmndnccrn", "sbo": "SBO:0000247"}}, {"charge": 1, "name": "Sodium", "formula": "Na", "compartment": "c", "id": "na1_c", "annotation": {"bigg.metabolite": "na1", "sbo": "SBO:0000247", "kegg.compound": "C01330"}}, {"charge": 0, "name": "Deoxyribose", "formula": "C5H10O4", "compartment": "c", "id": "drib_c", "annotation": {"bigg.metabolite": "drib", "sbo": "SBO:0000247", "kegg.compound": "C01801"}}, {"charge": 1, "name": "L-Tyrosyl-tRNA(Tyr)", "formula": "C9H11NO3R", "compartment": "m", "id": "tyrtrna_m", "annotation": {"bigg.metabolite": "tyrtrna", "sbo": "SBO:0000247", "kegg.compound": "C02839"}}, {"charge": -2, "name": "Molybdate", "formula": "MoO4", "compartment": "c", "id": "mobd_c", "annotation": {"bigg.metabolite": "mobd", "sbo": "SBO:0000247", "kegg.compound": "C06232"}}, {"charge": -1, "name": "4-Hydroxy-2-quinolinecarboxylic acid", "formula": "C10H6NO3", "compartment": "e", "id": "kynate_e", "annotation": {"bigg.metabolite": "kynate", "sbo": "SBO:0000247", "kegg.compound": "C01717"}}, {"charge": -1, "name": "gamma-L-Glutamyl-L-cysteine", "formula": "C8H13N2O5S", "compartment": "e", "id": "glucys_e", "annotation": {"bigg.metabolite": "glucys", "sbo": "SBO:0000247", "kegg.compound": "C00669"}}, {"charge": -6, "name": "\"1D-myo-Inositol 1,4,5-trisphosphate\"", "formula": "C6H9O15P3", "compartment": "c", "id": "mi145p_c", "annotation": {"bigg.metabolite": "mi145p", "sbo": "SBO:0000247", "kegg.compound": "C01245"}}, {"charge": -6, "name": "\"1D-myo-Inositol 1,3,4-trisphosphate\"", "formula": "C6H9O15P3", "compartment": "c", "id": "mi134p_c", "annotation": {"bigg.metabolite": "mi134p", "sbo": "SBO:0000247", "kegg.compound": "C01243"}}, {"charge": -4, "name": "Tetradecanoyl-CoA (n-C14:0CoA)", "formula": "C35H58N7O17P3S", "compartment": "c", "id": "tdcoa_c", "annotation": {"bigg.metabolite": "tdcoa", "sbo": "SBO:0000247", "kegg.compound": "C02593"}}, {"charge": -1, "name": "2-Aminomuconate", "formula": "C6H6NO4", "compartment": "c", "id": "amuco_c", "annotation": {"bigg.metabolite": "amuco", "sbo": "SBO:0000247", "kegg.compound": "C02220"}}, {"charge": 1, "name": "1-Methylnicotinamide", "formula": "C7H9N2O", "compartment": "c", "id": "1mncam_c", "annotation": {"bigg.metabolite": "1mncam", "sbo": "SBO:0000247", "kegg.compound": "C02918"}}, {"charge": -4, "name": "4-hydroxybenoyl-CoA", "formula": "C28H36N7O18P3S", "compartment": "m", "id": "4hbzcoa_m", "annotation": {"bigg.metabolite": "4hbzcoa", "sbo": "SBO:0000247", "kegg.compound": "C02949"}}, {"charge": 0, "name": "Glycine betaine", "formula": "C5H11NO2", "compartment": "e", "id": "glyb_e", "annotation": {"bigg.metabolite": "glyb", "sbo": "SBO:0000247", "kegg.compound": "C00719"}}, {"charge": 1, "name": "L-Leucyl-tRNA(Leu)", "formula": "C6H13NO2R", "compartment": "c", "id": "leutrna_c", "annotation": {"bigg.metabolite": "leutrna", "sbo": "SBO:0000247", "kegg.compound": "C02047"}}, {"charge": 0, "name": "\"7-alpha,27-Dihydroxycholesterol\"", "formula": "C27H46O3", "compartment": "c", "id": "xoltri27_c", "annotation": {"bigg.metabolite": "xoltri27", "sbo": "SBO:0000247", "kegg.compound": "C06341"}}, {"charge": 0, "name": "tRNA(Tyr)", "formula": "ROH", "compartment": "m", "id": "trnatyr_m", "annotation": {"bigg.metabolite": "trnatyr", "sbo": "SBO:0000247", "kegg.compound": "C00787"}}, {"charge": -1, "name": "octadecanoate (n-C18:0)", "formula": "C18H35O2", "compartment": "e", "id": "ocdca_e", "annotation": {"bigg.metabolite": "ocdca", "sbo": "SBO:0000247", "kegg.compound": "C01530"}}, {"charge": 1, "name": "L-Asparaginyl-tRNA(Asn)", "formula": "C4H8N2O3R", "compartment": "c", "id": "asntrna_c", "annotation": {"bigg.metabolite": "asntrna", "sbo": "SBO:0000247", "kegg.compound": "C03402"}}, {"charge": 0, "name": "\"7alpha,12alpha-Dihydroxy-5beta-cholestan-3-one\"", "formula": "C27H46O3", "compartment": "c", "id": "xoldioloneh_c", "annotation": {"bigg.metabolite": "xoldioloneh", "sbo": "SBO:0000247", "kegg.compound": "C05453"}}, {"charge": -2, "name": "5-Methylthio-5-deoxy-D-ribose 1-phosphate", "formula": "C6H11O7PS", "compartment": "c", "id": "5mdr1p_c", "annotation": {"bigg.metabolite": "5mdr1p", "sbo": "SBO:0000247", "kegg.compound": "C04188"}}, {"charge": 0, "name": "7alpha-Hydroxycholest-4-en-3-one", "formula": "C27H44O2", "compartment": "c", "id": "xol7aone_c", "annotation": {"bigg.metabolite": "xol7aone", "sbo": "SBO:0000247", "kegg.compound": "C05455"}}, {"charge": 0, "name": "\"3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestane\"", "formula": "C27H48O3", "compartment": "c", "id": "xoltriol_c", "annotation": {"bigg.metabolite": "xoltriol", "sbo": "SBO:0000247", "kegg.compound": "C05454"}}, {"charge": 1, "name": "L-Leucyl-tRNA(Leu)", "formula": "C6H13NO2R", "compartment": "m", "id": "leutrna_m", "annotation": {"bigg.metabolite": "leutrna", "sbo": "SBO:0000247", "kegg.compound": "C02047"}}, {"charge": -1, "name": "Prostaglandin D2", "formula": "C20H31O5", "compartment": "c", "id": "prostgd2_c", "annotation": {"bigg.metabolite": "prostgd2", "sbo": "SBO:0000247", "kegg.compound": "C00696"}}, {"charge": -1, "name": "Cholate", "formula": "C24H39O5", "compartment": "c", "id": "cholate_c", "annotation": {"bigg.metabolite": "cholate", "sbo": "SBO:0000247", "kegg.compound": "C00695"}}, {"charge": -1, "name": "Chloride", "formula": "Cl", "compartment": "c", "id": "cl_c", "annotation": {"bigg.metabolite": "cl", "sbo": "SBO:0000247", "kegg.compound": "C00698"}}, {"charge": 0, "name": "androsterone glucuronide", "formula": "C25H38O8", "compartment": "e", "id": "andrstrnglc_e", "annotation": {"bigg.metabolite": "andrstrnglc", "sbo": "SBO:0000247", "kegg.compound": "C11135"}}, {"charge": -1, "name": "L-Cysteate", "formula": "C3H6NO5S", "compartment": "c", "id": "Lcyst_c", "annotation": {"bigg.metabolite": "Lcyst", "sbo": "SBO:0000247", "kegg.compound": "C00506"}}, {"charge": -4, "name": "trans-Octadec-2-enoyl-CoA", "formula": "C39H64N7O17P3S", "compartment": "c", "id": "od2coa_c", "annotation": {"bigg.metabolite": "od2coa", "sbo": "SBO:0000247", "kegg.compound": "C16218"}}, {"charge": -1, "name": "Folate", "formula": "C19H18N7O6", "compartment": "c", "id": "fol_c", "annotation": {"bigg.metabolite": "fol", "sbo": "SBO:0000247", "kegg.compound": "C00504"}}, {"charge": -2, "name": "Nicotinate D-ribonucleotide", "formula": "C11H12NO9P", "compartment": "c", "id": "nicrnt_c", "annotation": {"bigg.metabolite": "nicrnt", "sbo": "SBO:0000247", "kegg.compound": "C01185"}}, {"charge": -4, "name": "(S)-3-Hydroxyoctadecanoyl-CoA", "formula": "C39H66N7O18P3S", "compartment": "c", "id": "3hodcoa_c", "annotation": {"bigg.metabolite": "3hodcoa", "sbo": "SBO:0000247", "kegg.compound": "C16217"}}, {"charge": -4, "name": "3-Oxooctadecanoyl-CoA", "formula": "C39H64N7O18P3S", "compartment": "c", "id": "3oodcoa_c", "annotation": {"bigg.metabolite": "3oodcoa", "sbo": "SBO:0000247", "kegg.compound": "C16216"}}, {"charge": -4, "name": "3-Methylbut-2-enoyl-CoA", "formula": "C26H38N7O17P3S", "compartment": "m", "id": "3mb2coa_m", "annotation": {"bigg.metabolite": "3mb2coa", "sbo": "SBO:0000247", "kegg.compound": "C03069"}}, {"charge": 0, "name": "L-Kynurenine", "formula": "C10H12N2O3", "compartment": "c", "id": "Lkynr_c", "annotation": {"bigg.metabolite": "Lkynr", "sbo": "SBO:0000247", "kegg.compound": "C00328"}}, {"charge": 1, "name": "D-Glucosamine", "formula": "C6H14NO5", "compartment": "c", "id": "gam_c", "annotation": {"bigg.metabolite": "gam", "sbo": "SBO:0000247", "kegg.compound": "C00329"}}, {"charge": -2, "name": "2-Oxoadipate", "formula": "C6H6O5", "compartment": "c", "id": "2oxoadp_c", "annotation": {"bigg.metabolite": "2oxoadp", "sbo": "SBO:0000247", "kegg.compound": "C00322"}}, {"charge": -2, "name": "Thiosulfate", "formula": "O3S2", "compartment": "c", "id": "tsul_c", "annotation": {"bigg.metabolite": "tsul", "sbo": "SBO:0000247", "kegg.compound": "C00320"}}, {"charge": -2, "name": "GDP-L-fucose", "formula": "C16H23N5O15P2", "compartment": "c", "id": "gdpfuc_c", "annotation": {"bigg.metabolite": "gdpfuc", "sbo": "SBO:0000247", "kegg.compound": "C00325"}}, {"charge": -1, "name": "arachidonic acid", "formula": "C20H31O2", "compartment": "c", "id": "arachd_c", "annotation": {"bigg.metabolite": "arachd", "sbo": "SBO:0000247", "kegg.compound": "C00219"}}, {"charge": 0, "name": "Thymidine", "formula": "C10H14N2O5", "compartment": "c", "id": "thymd_c", "annotation": {"bigg.metabolite": "thymd", "sbo": "SBO:0000247", "kegg.compound": "C00214"}}, {"charge": 0, "name": "Adenosine", "formula": "C10H13N5O4", "compartment": "c", "id": "adn_c", "annotation": {"bigg.metabolite": "adn", "sbo": "SBO:0000247", "kegg.compound": "C00212"}}, {"charge": -2, "name": "Oxaloacetate", "formula": "C4H2O5", "compartment": "c", "id": "oaa_c", "annotation": {"bigg.metabolite": "oaa", "sbo": "SBO:0000247", "kegg.compound": "C00036"}}, {"charge": 0, "name": "Glycine", "formula": "C2H5NO2", "compartment": "c", "id": "gly_c", "annotation": {"bigg.metabolite": "gly", "sbo": "SBO:0000247", "kegg.compound": "C00037"}}, {"charge": -3, "name": "GDP", "formula": "C10H12N5O11P2", "compartment": "c", "id": "gdp_c", "annotation": {"bigg.metabolite": "gdp", "sbo": "SBO:0000247", "kegg.compound": "C00035"}}, {"charge": 0, "name": "Protoheme", "formula": "C34H30FeN4O4", "compartment": "c", "id": "pheme_c", "annotation": {"bigg.metabolite": "pheme", "sbo": "SBO:0000247", "kegg.compound": "C00032"}}, {"charge": -1, "name": "Acetate", "formula": "C2H3O2", "compartment": "c", "id": "ac_c", "annotation": {"bigg.metabolite": "ac", "sbo": "SBO:0000247", "kegg.compound": "C00033"}}, {"charge": -1, "name": "Acetoacetate", "formula": "C4H5O3", "compartment": "m", "id": "acac_m", "annotation": {"bigg.metabolite": "acac", "sbo": "SBO:0000247", "kegg.compound": "C00164"}}, {"charge": 0, "name": "D-Glucose", "formula": "C6H12O6", "compartment": "c", "id": "glc-D_c", "annotation": {"bigg.metabolite": "glc-D", "sbo": "SBO:0000247", "kegg.compound": "C00031"}}, {"charge": -1, "name": "Hydroxypyruvate", "formula": "C3H3O4", "compartment": "m", "id": "hpyr_m", "annotation": {"bigg.metabolite": "hpyr", "sbo": "SBO:0000247", "kegg.compound": "C00168"}}, {"charge": 0, "name": "25-Hydroxycholesterol", "formula": "C27H46O2", "compartment": "e", "id": "xol25oh_e", "annotation": {"bigg.metabolite": "xol25oh", "sbo": "SBO:0000247", "kegg.compound": "C15519"}}, {"charge": -1, "name": "5-Hydroxyindoleacetate", "formula": "C10H8NO3", "compartment": "c", "id": "5hoxindoa_c", "annotation": {"bigg.metabolite": "5hoxindoa", "sbo": "SBO:0000247", "kegg.compound": "C05635"}}, {"charge": 0, "name": "5-Hydroxyindoleacetaldehyde", "formula": "C10H9NO2", "compartment": "c", "id": "5hoxindact_c", "annotation": {"bigg.metabolite": "5hoxindact", "sbo": "SBO:0000247", "kegg.compound": "C05634"}}, {"charge": 1, "name": "N6,N6,N6-Trimethyl-L-lysine", "formula": "C9H21N2O2", "compartment": "m", "id": "tmlys_m", "annotation": {"bigg.metabolite": "tmlys", "sbo": "SBO:0000247", "kegg.compound": "C03793"}}, {"charge": 0, "name": "Formaldehyde", "formula": "CH2O", "compartment": "e", "id": "fald_e", "annotation": {"bigg.metabolite": "fald", "sbo": "SBO:0000247", "kegg.compound": "C00067"}}, {"charge": 0, "name": "L-Serine", "formula": "C3H7NO3", "compartment": "e", "id": "ser-L_e", "annotation": {"bigg.metabolite": "ser-L", "sbo": "SBO:0000247", "kegg.compound": "C00065"}}, {"charge": 0, "name": "L-Glutamine", "formula": "C5H10N2O3", "compartment": "e", "id": "gln-L_e", "annotation": {"bigg.metabolite": "gln-L", "sbo": "SBO:0000247", "kegg.compound": "C00064"}}, {"charge": 1, "name": "L-Arginine", "formula": "C6H15N4O2", "compartment": "e", "id": "arg-L_e", "annotation": {"bigg.metabolite": "arg-L", "sbo": "SBO:0000247", "kegg.compound": "C00062"}}, {"charge": -2, "name": "FMN", "formula": "C17H19N4O9P", "compartment": "e", "id": "fmn_e", "annotation": {"bigg.metabolite": "fmn", "sbo": "SBO:0000247", "kegg.compound": "C00061"}}, {"charge": 0, "name": "27-Hydroxycholesterol", "formula": "C27H46O2", "compartment": "c", "id": "xol27oh_c", "annotation": {"bigg.metabolite": "xol27oh", "sbo": "SBO:0000247", "kegg.compound": "C15610"}}, {"charge": -4, "name": "\"3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoyl-CoA\"", "formula": "C48H76N7O20P3S", "compartment": "c", "id": "cholcoar_c", "annotation": {"bigg.metabolite": "cholcoar", "sbo": "SBO:0000247", "kegg.compound": "C15613"}}, {"charge": -3, "name": "Orotidine 5'-phosphate", "formula": "C10H10N2O11P", "compartment": "c", "id": "orot5p_c", "annotation": {"bigg.metabolite": "orot5p", "sbo": "SBO:0000247", "kegg.compound": "C01103"}}, {"charge": 0, "name": "Trimethylamine N-oxide", "formula": "C3H9NO", "compartment": "c", "id": "tmao_c", "annotation": {"bigg.metabolite": "tmao", "sbo": "SBO:0000247", "kegg.compound": "C01104"}}, {"charge": -3, "name": "(R)-5-Phosphomevalonate", "formula": "C6H10O7P", "compartment": "c", "id": "5pmev_c", "annotation": {"bigg.metabolite": "5pmev", "sbo": "SBO:0000247", "kegg.compound": "C01107"}}, {"charge": 1, "name": "N-Methylhistamine", "formula": "C6H12N3", "compartment": "c", "id": "mhista_c", "annotation": {"bigg.metabolite": "mhista", "sbo": "SBO:0000247", "kegg.compound": "C05127"}}, {"charge": 0, "name": "L-2-Aminoadipate 6-semialdehyde", "formula": "C6H11NO3", "compartment": "m", "id": "L2aadp6sa_m", "annotation": {"bigg.metabolite": "L2aadp6sa", "sbo": "SBO:0000247", "kegg.compound": "C04076"}}, {"charge": 0, "name": "taurocholic acid", "formula": "C26H45NO7S", "compartment": "c", "id": "tchola_c", "annotation": {"bigg.metabolite": "tchola", "sbo": "SBO:0000247", "kegg.compound": "C05122"}}, {"charge": 0, "name": "Formaldehyde", "formula": "CH2O", "compartment": "m", "id": "fald_m", "annotation": {"bigg.metabolite": "fald", "sbo": "SBO:0000247", "kegg.compound": "C00067"}}, {"charge": 1, "name": "L-Seryl-tRNA(Ser)", "formula": "C3H7NO3R", "compartment": "m", "id": "sertrna_m", "annotation": {"bigg.metabolite": "sertrna", "sbo": "SBO:0000247", "kegg.compound": "C02553"}}, {"charge": 1, "name": "L-Valyl-tRNA(Val)", "formula": "C5H11NO2R", "compartment": "m", "id": "valtrna_m", "annotation": {"bigg.metabolite": "valtrna", "sbo": "SBO:0000247", "kegg.compound": "C02554"}}, {"charge": 0, "name": "Palmitoleyl carnitine", "formula": "C23H43NO4", "compartment": "m", "id": "fa16p1n7crn_m", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -1, "name": "Ascaroside 3", "formula": "C15H25O6", "compartment": "c", "id": "ascr3_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 0, "name": "Cytidine", "formula": "C9H13N3O5", "compartment": "e", "id": "cytd_e", "annotation": {"bigg.metabolite": "cytd", "sbo": "SBO:0000247", "kegg.compound": "C00475"}}, {"charge": 0, "name": "Retinol", "formula": "C20H30O", "compartment": "e", "id": "retinol_e", "annotation": {"bigg.metabolite": "retinol", "sbo": "SBO:0000247", "kegg.compound": "C00473"}}, {"charge": -2, "name": "4-Maleylacetoacetate", "formula": "C8H6O6", "compartment": "c", "id": "4mlacac_c", "annotation": {"bigg.metabolite": "4mlacac", "sbo": "SBO:0000247", "kegg.compound": "C01036"}}, {"charge": -1, "name": "S-Formylglutathione", "formula": "C11H16N3O7S", "compartment": "c", "id": "Sfglutth_c", "annotation": {"bigg.metabolite": "Sfglutth", "sbo": "SBO:0000247", "kegg.compound": "C01031"}}, {"charge": 0, "name": "Octadecenoyl carnitine", "formula": "C25H47NO4", "compartment": "m", "id": "odecrn_m", "annotation": {"bigg.metabolite": "odecrn", "sbo": "SBO:0000247"}}, {"charge": 0, "name": "Vaccenyl carnitine", "formula": "C25H47NO4", "compartment": "m", "id": "vacccrn_m", "annotation": {"bigg.metabolite": "vacccrn", "sbo": "SBO:0000247"}}, {"charge": 0, "name": "2-Phenylacetamide", "formula": "C8H9NO", "compartment": "c", "id": "pad_c", "annotation": {"bigg.metabolite": "pad", "sbo": "SBO:0000247", "kegg.compound": "C02505"}}, {"charge": -1, "name": "3-Hydroxypropanoate", "formula": "C3H5O3", "compartment": "e", "id": "3hpp_e", "annotation": {"bigg.metabolite": "3hpp", "sbo": "SBO:0000247", "kegg.compound": "C01013"}}, {"charge": 0, "name": "27-Hydroxycholesterol", "formula": "C27H46O2", "compartment": "m", "id": "xol27oh_m", "annotation": {"bigg.metabolite": "xol27oh", "sbo": "SBO:0000247", "kegg.compound": "C15610"}}, {"charge": 0, "name": "1-Alkyl-2-lyso-sn-glycero-3-phosphocholine", "formula": "C26.0H56.0N1.0O6.0P1.0", "compartment": "e", "id": "ak2lgchol_e", "annotation": {"bigg.metabolite": "ak2lgchol_hs", "sbo": "SBO:0000247", "kegg.compound": "C04317"}}, {"charge": 0, "name": "tRNA(Asn)", "formula": "ROH", "compartment": "c", "id": "trnaasn_c", "annotation": {"bigg.metabolite": "trnaasn", "sbo": "SBO:0000247", "kegg.compound": "C01637"}}, {"charge": 0, "name": "tRNA(Arg)", "formula": "ROH", "compartment": "c", "id": "trnaarg_c", "annotation": {"bigg.metabolite": "trnaarg", "sbo": "SBO:0000247", "kegg.compound": "C01636"}}, {"charge": 0, "name": "tRNA(Ala)", "formula": "ROH", "compartment": "c", "id": "trnaala_c", "annotation": {"bigg.metabolite": "trnaala", "sbo": "SBO:0000247", "kegg.compound": "C01635"}}, {"charge": -2, "name": "\"7,8-Dihydrofolate\"", "formula": "C19H19N7O6", "compartment": "m", "id": "dhf_m", "annotation": {"bigg.metabolite": "dhf", "sbo": "SBO:0000247", "kegg.compound": "C00415"}}, {"charge": -4, "name": "Stearoyl-CoA (n-C18:0CoA)", "formula": "C39H66N7O17P3S", "compartment": "m", "id": "stcoa_m", "annotation": {"bigg.metabolite": "stcoa", "sbo": "SBO:0000247", "kegg.compound": "C00412"}}, {"charge": -4, "name": "(S)-3-Hydroxybutanoyl-CoA", "formula": "C25H38N7O18P3S", "compartment": "m", "id": "3hbcoa_m", "annotation": {"bigg.metabolite": "3hbcoa", "sbo": "SBO:0000247", "kegg.compound": "C01144"}}, {"charge": 1, "name": "Phenethylamine", "formula": "C8H12N", "compartment": "c", "id": "peamn_c", "annotation": {"bigg.metabolite": "peamn", "sbo": "SBO:0000247", "kegg.compound": "C05332"}}, {"charge": 0, "name": "tRNA(Cys)", "formula": "ROH", "compartment": "c", "id": "trnacys_c", "annotation": {"bigg.metabolite": "trnacys", "sbo": "SBO:0000247", "kegg.compound": "C01639"}}, {"charge": 0, "name": "tRNA(Asp)", "formula": "ROH", "compartment": "c", "id": "trnaasp_c", "annotation": {"bigg.metabolite": "trnaasp", "sbo": "SBO:0000247", "kegg.compound": "C01638"}}, {"charge": -1, "name": "hydroxide ion", "formula": "HO", "compartment": "c", "id": "oh1_c", "annotation": {"bigg.metabolite": "oh1", "sbo": "SBO:0000247", "kegg.compound": "C01328"}}, {"charge": 1, "name": "Histamine", "formula": "C5H10N3", "compartment": "e", "id": "hista_e", "annotation": {"bigg.metabolite": "hista", "sbo": "SBO:0000247", "kegg.compound": "C00388"}}, {"charge": -1, "name": "Sphinganine 1-phosphate", "formula": "C19H41NO5P", "compartment": "c", "id": "sph1p_ce_c", "annotation": {"bigg.metabolite": "sph1p", "sbo": "SBO:0000247"}}, {"charge": 0, "name": "15-methylhexadecanal", "formula": "C17H34O", "compartment": "c", "id": "m15hxdcal_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 1, "name": "3-Dehydrosphinganine", "formula": "C19H40NO2", "compartment": "c", "id": "3dsphgn_ce_c", "annotation": {"bigg.metabolite": "3dsphgn", "sbo": "SBO:0000247"}}, {"charge": 1, "name": "Sphinganine", "formula": "C19H42NO2", "compartment": "c", "id": "sphgn_ce_c", "annotation": {"bigg.metabolite": "sphgn", "sbo": "SBO:0000247"}}, {"charge": 0, "name": "dihydroceramide ", "formula": "C37.5654H71.5778N1.0O3.0", "compartment": "c", "id": "dhcrm_ce_c", "annotation": {"bigg.metabolite": "dhcrm_hs", "sbo": "SBO:0000247"}}, {"charge": 0, "name": "ceramide ", "formula": "C37.5654H69.5778N1.0O3.0", "compartment": "c", "id": "crm_ce_c", "annotation": {"bigg.metabolite": "crm_hs", "sbo": "SBO:0000247"}}, {"charge": -2, "name": "Ceramide 1-phosphate", "formula": "C37.5654H68.5778N1.0O6.0P1.0", "compartment": "c", "id": "crmp_ce_c", "annotation": {"bigg.metabolite": "crmp_hs", "sbo": "SBO:0000247"}}, {"charge": 1, "name": "sphingosylphosphorylcholine ", "formula": "C24H52N2O5P", "compartment": "c", "id": "spc_ce_c", "annotation": {"bigg.metabolite": "spc_hs", "sbo": "SBO:0000247"}}, {"charge": 1, "name": "proton (pumped)", "formula": "H", "compartment": "c", "id": "h_pumped_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 0, "name": "Sphingomyelin", "formula": "C42.5654H81.5778N2.0O6.0P1.0", "compartment": "c", "id": "sphmyln_ce_c", "annotation": {"bigg.metabolite": "sphmyln_hs", "sbo": "SBO:0000247"}}, {"charge": 0, "name": "glycogen", "formula": "C6H10O5", "compartment": "e", "id": "glycogen_BAC_e", "annotation": {"bigg.metabolite": "glycogen", "sbo": "SBO:0000247"}}, {"charge": -1, "name": "3-(4-Hydroxyphenyl)lactate", "formula": "C9H9O4", "compartment": "c", "id": "34hpl_c", "annotation": {"bigg.metabolite": "34hpl", "sbo": "SBO:0000247", "kegg.compound": "C03672"}}, {"charge": -2, "name": "Xanthosine 5'-phosphate", "formula": "C10H11N4O9P", "compartment": "e", "id": "xmp_e", "annotation": {"bigg.metabolite": "xmp", "sbo": "SBO:0000247", "kegg.compound": "C00655"}}, {"charge": -1, "name": "3-nonaprenyl-4,5-dihydroxybenzoate", "formula": "C52H77O4", "compartment": "m", "id": "3npdhb_m", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -1, "name": "3-nonaprenyl-4-hydroxy-5-methoxybenzoate", "formula": "C53H79O4", "compartment": "m", "id": "3npdhb_me_m", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -6, "name": "pentaglutamyl folate (THF)", "formula": "C39H45N11O18", "compartment": "m", "id": "5thf_m", "annotation": {"bigg.metabolite": "5thf", "sbo": "SBO:0000247"}}, {"charge": -8, "name": "heptaglutamyl folate (THF)", "formula": "C49H57N13O24", "compartment": "m", "id": "7thf_m", "annotation": {"bigg.metabolite": "7thf", "sbo": "SBO:0000247"}}, {"charge": 0, "name": "2-nonaprenyl-6-methoxyphenol", "formula": "C52H80O2", "compartment": "m", "id": "2np6mep_m", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 1, "name": "Betaine aldehyde", "formula": "C5H12NO", "compartment": "m", "id": "betald_m", "annotation": {"bigg.metabolite": "betald", "sbo": "SBO:0000247", "kegg.compound": "C00576"}}, {"charge": 0, "name": "glycocholate", "formula": "C26H43NO6", "compartment": "c", "id": "gchola_c", "annotation": {"bigg.metabolite": "gchola", "sbo": "SBO:0000247", "kegg.compound": "C01921"}}, {"charge": -1, "name": "\"4-(2-Aminophenyl)-2,4-dioxobutanoate\"", "formula": "C10H8NO4", "compartment": "c", "id": "4aphdob_c", "annotation": {"bigg.metabolite": "4aphdob", "sbo": "SBO:0000247", "kegg.compound": "C01252"}}, {"charge": 1, "name": "3-Hydroxy-N6,N6,N6-trimethyl-L-lysine", "formula": "C9H21N2O3", "compartment": "c", "id": "3htmelys_c", "annotation": {"bigg.metabolite": "3htmelys", "sbo": "SBO:0000247", "kegg.compound": "C01259"}}, {"charge": 0, "name": "N4-Acetylaminobutanal", "formula": "C6H11NO2", "compartment": "c", "id": "n4abutn_c", "annotation": {"bigg.metabolite": "n4abutn", "sbo": "SBO:0000247", "kegg.compound": "C05936"}}, {"charge": -4, "name": "Intermediary fatty acid C14:2", "formula": "C35H54N7O17P3S", "compartment": "m", "id": "fa14p2n6coa_m", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -2, "name": "Dihydroxyacetone phosphate", "formula": "C3H5O6P", "compartment": "e", "id": "dhap_e", "annotation": {"bigg.metabolite": "dhap", "sbo": "SBO:0000247", "kegg.compound": "C00111"}}, {"charge": 0, "name": "sedoheptulose", "formula": "C7H14O7", "compartment": "c", "id": "sedh_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C02076"}}, {"charge": 0, "name": "\"D-glucurono-6,3-lactone\"", "formula": "C6H8O6", "compartment": "c", "id": "glac_c", "annotation": {"bigg.metabolite": "glac", "sbo": "SBO:0000247", "kegg.compound": "C02670"}}, {"charge": -1, "name": "Dodecanoate (n-C12:0)", "formula": "C12H23O2", "compartment": "c", "id": "ddca_c", "annotation": {"bigg.metabolite": "ddca", "sbo": "SBO:0000247", "kegg.compound": "C02679"}}, {"charge": -1, "name": "Cyclic pyranopterin monophosphate", "formula": "C10H11N5O7P", "compartment": "c", "id": "cpmp_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C18239"}}, {"charge": -2, "name": "(alpha-D-Mannosyl)8-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol", "formula": "C180H296N2O62P2", "compartment": "c", "id": "m8mpdol_c", "annotation": {"bigg.metabolite": ["m8mpdol_L", "m8mpdol_U"], "sbo": "SBO:0000247"}}, {"charge": -1, "name": "5-Phospho-beta-D-ribosylamine", "formula": "C5H11NO7P", "compartment": "c", "id": "pram_c", "annotation": {"bigg.metabolite": "pram", "sbo": "SBO:0000247", "kegg.compound": "C03090"}}, {"charge": -1, "name": "L-2-Aminoadipate", "formula": "C6H10NO4", "compartment": "m", "id": "L2aadp_m", "annotation": {"bigg.metabolite": "L2aadp", "sbo": "SBO:0000247", "kegg.compound": "C00956"}}, {"charge": -1, "name": "Indole-3-acetate", "formula": "C10H8NO2", "compartment": "m", "id": "ind3ac_m", "annotation": {"bigg.metabolite": "ind3ac", "sbo": "SBO:0000247", "kegg.compound": "C00954"}}, {"charge": 3, "name": "Fe3+", "formula": "Fe", "compartment": "e", "id": "fe3_e", "annotation": {"bigg.metabolite": "fe3", "sbo": "SBO:0000247", "kegg.compound": "C14819"}}, {"charge": 2, "name": "Fe2+", "formula": "Fe", "compartment": "e", "id": "fe2_e", "annotation": {"bigg.metabolite": "fe2", "sbo": "SBO:0000247", "kegg.compound": "C14818"}}, {"charge": -3, "name": "phosphatidyl glycerol phosphate ", "formula": "C43.1308H74.1556O13.0P2.0", "compartment": "c", "id": "pgp_c", "annotation": {"bigg.metabolite": "pgp_hs", "sbo": "SBO:0000247", "kegg.compound": "C03892"}}, {"charge": -2, "name": "Lysophosphatidic acid (phospholipids)", "formula": "C21.5654H37.5778O7.0P1.0", "compartment": "c", "id": "alpa_pl_c", "annotation": {"bigg.metabolite": "alpa_hs", "sbo": "SBO:0000247", "kegg.compound": "C00681"}}, {"charge": -2, "name": "\"alpha,alpha'-Trehalose 6-phosphate\"", "formula": "C12H21O14P", "compartment": "c", "id": "tre6p_c", "annotation": {"bigg.metabolite": "tre6p", "sbo": "SBO:0000247", "kegg.compound": "C00689"}}, {"charge": -4, "name": "Octadecenoyl-CoA (n-C18:1CoA)", "formula": "C39H64N7O17P3S", "compartment": "c", "id": "odecoa_c", "annotation": {"bigg.metabolite": "odecoa", "sbo": "SBO:0000247", "kegg.compound": "C00510"}}, {"charge": -1, "name": "Hypotaurine", "formula": "C2H6NO2S", "compartment": "c", "id": "hyptaur_c", "annotation": {"bigg.metabolite": "hyptaur", "sbo": "SBO:0000247", "kegg.compound": "C00519"}}, {"charge": 0, "name": "hydroxy alkyl chain", "formula": "C18.0H38.0O1.0", "compartment": "c", "id": "alkylR1oh_c", "annotation": {"bigg.metabolite": "alkylR1oh", "sbo": "SBO:0000247", "kegg.compound": "C00339"}}, {"charge": 0, "name": "Deoxyguanosine", "formula": "C10H13N5O4", "compartment": "c", "id": "dgsn_c", "annotation": {"bigg.metabolite": "dgsn", "sbo": "SBO:0000247", "kegg.compound": "C00330"}}, {"charge": -4, "name": "Acetoacetyl-CoA", "formula": "C25H36N7O18P3S", "compartment": "c", "id": "aacoa_c", "annotation": {"bigg.metabolite": "aacoa", "sbo": "SBO:0000247", "kegg.compound": "C00332"}}, {"charge": 0, "name": "4-Aminobutanoate", "formula": "C4H9NO2", "compartment": "c", "id": "4abut_c", "annotation": {"bigg.metabolite": "4abut", "sbo": "SBO:0000247", "kegg.compound": "C00334"}}, {"charge": -1, "name": "(S)-Dihydroorotate", "formula": "C5H5N2O4", "compartment": "c", "id": "dhor-S_c", "annotation": {"bigg.metabolite": "dhor-S", "sbo": "SBO:0000247", "kegg.compound": "C00337"}}, {"charge": 0, "name": "3,4-Dihydroxyphenylacetaldehyde", "formula": "C8H8O3", "compartment": "c", "id": "34dhpac_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C04043"}}, {"charge": 0, "name": "Maltose", "formula": "C12H22O11", "compartment": "c", "id": "malt_c", "annotation": {"bigg.metabolite": "malt", "sbo": "SBO:0000247", "kegg.compound": "C00208"}}, {"charge": -3, "name": "dADP", "formula": "C10H12N5O9P2", "compartment": "c", "id": "dadp_c", "annotation": {"bigg.metabolite": "dadp", "sbo": "SBO:0000247", "kegg.compound": "C00206"}}, {"charge": -1, "name": "L-Glutamate", "formula": "C5H8NO4", "compartment": "c", "id": "glu-L_c", "annotation": {"bigg.metabolite": "glu-L", "sbo": "SBO:0000247", "kegg.compound": "C00025"}}, {"charge": -4, "name": "Acetyl-CoA", "formula": "C23H34N7O17P3S", "compartment": "c", "id": "accoa_c", "annotation": {"bigg.metabolite": "accoa", "sbo": "SBO:0000247", "kegg.compound": "C00024"}}, {"charge": 0, "name": "Hydrogen peroxide", "formula": "H2O2", "compartment": "c", "id": "h2o2_c", "annotation": {"bigg.metabolite": "h2o2", "sbo": "SBO:0000247", "kegg.compound": "C00027"}}, {"charge": -2, "name": "2-Oxoglutarate", "formula": "C5H4O5", "compartment": "c", "id": "akg_c", "annotation": {"bigg.metabolite": "akg", "sbo": "SBO:0000247", "kegg.compound": "C00026"}}, {"charge": 0, "name": "S-Adenosyl-L-homocysteine", "formula": "C14H20N6O5S", "compartment": "c", "id": "ahcys_c", "annotation": {"bigg.metabolite": "ahcys", "sbo": "SBO:0000247", "kegg.compound": "C00021"}}, {"charge": -2, "name": "AMP", "formula": "C10H12N5O7P", "compartment": "c", "id": "amp_c", "annotation": {"bigg.metabolite": "amp", "sbo": "SBO:0000247", "kegg.compound": "C00020"}}, {"charge": -1, "name": "Pyruvate", "formula": "C3H3O3", "compartment": "c", "id": "pyr_c", "annotation": {"bigg.metabolite": "pyr", "sbo": "SBO:0000247", "kegg.compound": "C00022"}}, {"charge": -2, "name": "UDPglucose", "formula": "C15H22N2O17P2", "compartment": "c", "id": "udpg_c", "annotation": {"bigg.metabolite": "udpg", "sbo": "SBO:0000247", "kegg.compound": "C00029"}}, {"charge": 0, "name": "\"7-alpha,25-Dihydroxycholesterol\"", "formula": "C27H46O3", "compartment": "e", "id": "xoltri25_e", "annotation": {"bigg.metabolite": "xoltri25", "sbo": "SBO:0000247", "kegg.compound": "C15520"}}, {"charge": 1, "name": "potassium", "formula": "K", "compartment": "e", "id": "k_e", "annotation": {"bigg.metabolite": "k", "sbo": "SBO:0000247", "kegg.compound": "C00238"}}, {"charge": -1, "name": "Dolichyl beta-D-glucosyl phosphate", "formula": "C116H190O9P", "compartment": "c", "id": "dolglcp_c", "annotation": {"bigg.metabolite": ["dolglcp_L", "dolglcp_U"], "sbo": "SBO:0000247", "kegg.compound": "C01246"}}, {"charge": -2, "name": "Pyridoxal 5'-phosphate", "formula": "C8H8NO6P", "compartment": "e", "id": "pydx5p_e", "annotation": {"bigg.metabolite": "pydx5p", "sbo": "SBO:0000247", "kegg.compound": "C00018"}}, {"charge": 1, "name": "S-Adenosyl-L-methionine", "formula": "C15H23N6O5S", "compartment": "e", "id": "amet_e", "annotation": {"bigg.metabolite": "amet", "sbo": "SBO:0000247", "kegg.compound": "C00019"}}, {"charge": 0, "name": "Peptide", "formula": "C2H4NO2R(C2H2NOR)n", "compartment": "e", "id": "pepd_e", "annotation": {"bigg.metabolite": "pepd", "sbo": "SBO:0000247", "kegg.compound": "C00012"}}, {"charge": 0, "name": "CO2", "formula": "CO2", "compartment": "e", "id": "co2_e", "annotation": {"bigg.metabolite": "co2", "sbo": "SBO:0000247", "kegg.compound": "C00011"}}, {"charge": -2, "name": "Flavin adenine dinucleotide oxidized", "formula": "C27H31N9O15P2", "compartment": "e", "id": "fad_e", "annotation": {"bigg.metabolite": "fad", "sbo": "SBO:0000247", "kegg.compound": "C00016"}}, {"charge": 1, "name": "Ammonium", "formula": "H4N", "compartment": "e", "id": "nh4_e", "annotation": {"bigg.metabolite": "nh4", "sbo": "SBO:0000247", "kegg.compound": "C00014"}}, {"charge": -1, "name": "Homogentisate", "formula": "C8H7O4", "compartment": "e", "id": "hgentis_e", "annotation": {"bigg.metabolite": "hgentis", "sbo": "SBO:0000247", "kegg.compound": "C00544"}}, {"charge": 0, "name": "4-Aminobutanoate", "formula": "C4H9NO2", "compartment": "e", "id": "4abut_e", "annotation": {"bigg.metabolite": "4abut", "sbo": "SBO:0000247", "kegg.compound": "C00334"}}, {"charge": 2, "name": "L-Lysine-tRNA (Lys)", "formula": "C6H15N2O2R", "compartment": "c", "id": "lystrna_c", "annotation": {"bigg.metabolite": "lystrna", "sbo": "SBO:0000247", "kegg.compound": "C01931"}}, {"charge": 0, "name": "Methylglyoxal", "formula": "C3H4O2", "compartment": "e", "id": "mthgxl_e", "annotation": {"bigg.metabolite": "mthgxl", "sbo": "SBO:0000247", "kegg.compound": "C00546"}}, {"charge": 0, "name": "(alpha-D-Glucosyl)-(alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)", "formula": "C80.0H134.0N4.0O63.0", "compartment": "c", "id": "g1m8masn_c", "annotation": {"bigg.metabolite": "g1m8masn", "sbo": "SBO:0000247"}}, {"charge": -1, "name": "Selenide", "formula": "HSe", "compartment": "c", "id": "seln_c", "annotation": {"bigg.metabolite": "seln", "sbo": "SBO:0000247", "kegg.compound": "C01528"}}, {"charge": -2, "name": "Pantetheine 4'-phosphate", "formula": "C11H21N2O7PS", "compartment": "c", "id": "pan4p_c", "annotation": {"bigg.metabolite": "pan4p", "sbo": "SBO:0000247", "kegg.compound": "C01134"}}, {"charge": 2, "name": "S-Adenosylmethioninamine", "formula": "C14H24N6O3S", "compartment": "c", "id": "ametam_c", "annotation": {"bigg.metabolite": "ametam", "sbo": "SBO:0000247", "kegg.compound": "C01137"}}, {"charge": 0, "name": "N-Acetyl-D-galactosamine", "formula": "C8H15NO6", "compartment": "c", "id": "acgal_c", "annotation": {"bigg.metabolite": "acgal", "sbo": "SBO:0000247", "kegg.compound": "C01132"}}, {"charge": -2, "name": "Oxidized glutathione", "formula": "C20H30N6O12S2", "compartment": "e", "id": "gthox_e", "annotation": {"bigg.metabolite": "gthox", "sbo": "SBO:0000247", "kegg.compound": "C00127"}}, {"charge": 0, "name": "D-Galactose", "formula": "C6H12O6", "compartment": "e", "id": "gal_e", "annotation": {"bigg.metabolite": "gal", "sbo": "SBO:0000247", "kegg.compound": "C00124"}}, {"charge": -2, "name": "Fumarate", "formula": "C4H2O4", "compartment": "e", "id": "fum_e", "annotation": {"bigg.metabolite": "fum", "sbo": "SBO:0000247", "kegg.compound": "C00122"}}, {"charge": 0, "name": "L-Leucine", "formula": "C6H13NO2", "compartment": "e", "id": "leu-L_e", "annotation": {"bigg.metabolite": "leu-L", "sbo": "SBO:0000247", "kegg.compound": "C00123"}}, {"charge": 0, "name": "D-Ribose", "formula": "C5H10O5", "compartment": "e", "id": "rib-D_e", "annotation": {"bigg.metabolite": "rib-D", "sbo": "SBO:0000247", "kegg.compound": "C00121"}}, {"charge": 0, "name": "25-Hydroxycholesterol", "formula": "C27H46O2", "compartment": "c", "id": "xol25oh_c", "annotation": {"bigg.metabolite": "xol25oh", "sbo": "SBO:0000247", "kegg.compound": "C15519"}}, {"charge": -4, "name": "4-Coumaroyl-CoA", "formula": "C30H38N7O18P3S", "compartment": "m", "id": "4cmcoa_m", "annotation": {"bigg.metabolite": "4cmcoa", "sbo": "SBO:0000247", "kegg.compound": "C00223"}}, {"charge": 0, "name": "Ethanol", "formula": "C2H6O", "compartment": "e", "id": "etoh_e", "annotation": {"bigg.metabolite": "etoh", "sbo": "SBO:0000247", "kegg.compound": "C00469"}}, {"charge": 0, "name": "L-Carnitine", "formula": "C7H15NO3", "compartment": "m", "id": "crn_m", "annotation": {"bigg.metabolite": "crn", "sbo": "SBO:0000247", "kegg.compound": "C00318"}}, {"charge": 0, "name": "\"6,7-Dihydrobiopterin\"", "formula": "C9H13N5O3", "compartment": "e", "id": "dhbpt_e", "annotation": {"bigg.metabolite": "dhbpt", "sbo": "SBO:0000247", "kegg.compound": "C00268"}}, {"charge": 0, "name": "L-4-Hydroxyglutamate semialdehyde", "formula": "C5H9NO4", "compartment": "m", "id": "4hglusa_m", "annotation": {"bigg.metabolite": "4hglusa", "sbo": "SBO:0000247", "kegg.compound": "C05938"}}, {"charge": 0, "name": "2-nonaprenyl-6-methoxy-1,4-benzoquinone", "formula": "C52H78O3", "compartment": "m", "id": "2np6mobq_m", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -3, "name": "Isocitrate", "formula": "C6H5O7", "compartment": "m", "id": "icit_m", "annotation": {"bigg.metabolite": "icit", "sbo": "SBO:0000247", "kegg.compound": "C00311"}}, {"charge": 0, "name": "Glycolaldehyde", "formula": "C2H4O2", "compartment": "e", "id": "gcald_e", "annotation": {"bigg.metabolite": "gcald", "sbo": "SBO:0000247", "kegg.compound": "C00266"}}, {"charge": -2, "name": "O-Phospho-L-serine", "formula": "C3H6NO6P", "compartment": "c", "id": "pser-L_c", "annotation": {"bigg.metabolite": "pser-L", "sbo": "SBO:0000247", "kegg.compound": "C01005"}}, {"charge": 0, "name": "Hypoxanthine", "formula": "C5H4N4O", "compartment": "e", "id": "hxan_e", "annotation": {"bigg.metabolite": "hxan", "sbo": "SBO:0000247", "kegg.compound": "C00262"}}, {"charge": -1, "name": "w-hydroxyl leukotriene B4", "formula": "C20H31O5", "compartment": "c", "id": "leuktrB4woh_c", "annotation": {"bigg.metabolite": "leuktrB4woh", "sbo": "SBO:0000247", "kegg.compound": "C04853"}}, {"charge": -4, "name": "(S)-3-Hydroxy-2-methylbutyryl-CoA", "formula": "C26H40N7O18P3S", "compartment": "m", "id": "3hmbcoa_m", "annotation": {"bigg.metabolite": "3hmbcoa", "sbo": "SBO:0000247", "kegg.compound": "C04405"}}, {"charge": -4, "name": "Choloyl-CoA", "formula": "C45H70N7O20P3S", "compartment": "c", "id": "cholcoa_c", "annotation": {"bigg.metabolite": "cholcoa", "sbo": "SBO:0000247", "kegg.compound": "C01794"}}, {"charge": -2, "name": "alpha-D-Ribose 1-phosphate", "formula": "C5H9O8P", "compartment": "c", "id": "r1p_c", "annotation": {"bigg.metabolite": "r1p", "sbo": "SBO:0000247", "kegg.compound": "C00620"}}, {"charge": 0, "name": "tRNA(Gly)", "formula": "ROH", "compartment": "c", "id": "trnagly_c", "annotation": {"bigg.metabolite": "trnagly", "sbo": "SBO:0000247", "kegg.compound": "C01642"}}, {"charge": 0, "name": "tRNA(His)", "formula": "ROH", "compartment": "c", "id": "trnahis_c", "annotation": {"bigg.metabolite": "trnahis", "sbo": "SBO:0000247", "kegg.compound": "C01643"}}, {"charge": 0, "name": "tRNA(Gln)", "formula": "ROH", "compartment": "c", "id": "trnagln_c", "annotation": {"bigg.metabolite": "trnagln", "sbo": "SBO:0000247", "kegg.compound": "C01640"}}, {"charge": 0, "name": "tRNA (Glu)", "formula": "ROH", "compartment": "c", "id": "trnaglu_c", "annotation": {"bigg.metabolite": "trnaglu", "sbo": "SBO:0000247", "kegg.compound": "C01641"}}, {"charge": 0, "name": "tRNA(Lys)", "formula": "ROH", "compartment": "c", "id": "trnalys_c", "annotation": {"bigg.metabolite": "trnalys", "sbo": "SBO:0000247", "kegg.compound": "C01646"}}, {"charge": 0, "name": "tRNA(Met)", "formula": "ROH", "compartment": "c", "id": "trnamet_c", "annotation": {"bigg.metabolite": "trnamet", "sbo": "SBO:0000247", "kegg.compound": "C01647"}}, {"charge": 0, "name": "tRNA(Ile)", "formula": "ROH", "compartment": "c", "id": "trnaile_c", "annotation": {"bigg.metabolite": "trnaile", "sbo": "SBO:0000247", "kegg.compound": "C01644"}}, {"charge": 0, "name": "tRNA(Leu)", "formula": "ROH", "compartment": "c", "id": "trnaleu_c", "annotation": {"bigg.metabolite": "trnaleu", "sbo": "SBO:0000247", "kegg.compound": "C01645"}}, {"charge": 0, "name": "tRNA(Phe)", "formula": "ROH", "compartment": "c", "id": "trnaphe_c", "annotation": {"bigg.metabolite": "trnaphe", "sbo": "SBO:0000247", "kegg.compound": "C01648"}}, {"charge": 0, "name": "tRNA(Pro)", "formula": "ROH", "compartment": "c", "id": "trnapro_c", "annotation": {"bigg.metabolite": "trnapro", "sbo": "SBO:0000247", "kegg.compound": "C01649"}}, {"charge": -1, "name": "Ascaroside 18", "formula": "C17H31O6", "compartment": "c", "id": "ascr18_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -2, "name": "Pantetheine 4'-phosphate", "formula": "C11H21N2O7PS", "compartment": "m", "id": "pan4p_m", "annotation": {"bigg.metabolite": "pan4p", "sbo": "SBO:0000247", "kegg.compound": "C01134"}}, {"charge": 1, "name": "Tryptamine", "formula": "C10H13N2", "compartment": "e", "id": "trypta_e", "annotation": {"bigg.metabolite": "trypta", "sbo": "SBO:0000247", "kegg.compound": "C00398"}}, {"charge": 0, "name": "trihexosyl ceramide ", "formula": "C55.5654H99.5778N1.0O18.0", "compartment": "c", "id": "thcrm_ce_c", "annotation": {"bigg.metabolite": "thcrm_hs", "sbo": "SBO:0000247"}}, {"charge": 0, "name": "galactosyl glucosyl ceramide", "formula": "C49.5654H89.5778N1.0O13.0", "compartment": "c", "id": "galgluside_ce_c", "annotation": {"bigg.metabolite": "galgluside_hs", "sbo": "SBO:0000247"}}, {"charge": 0, "name": "Forssman hapten", "formula": "C71.5654H125.5778N3.0O28.0", "compartment": "c", "id": "forssman_ce_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 0, "name": "globoside ", "formula": "C63.5654H112.5778N2.0O23.0", "compartment": "c", "id": "gbside_ce_c", "annotation": {"bigg.metabolite": "gbside_hs", "sbo": "SBO:0000247"}}, {"charge": 1, "name": "Sphingosine", "formula": "C19H40NO2", "compartment": "c", "id": "sphings_ce_c", "annotation": {"bigg.metabolite": "sphings", "sbo": "SBO:0000247"}}, {"charge": -1, "name": "Sphingosine 1-phosphate", "formula": "C19H39NO5P", "compartment": "c", "id": "sphs1p_ce_c", "annotation": {"bigg.metabolite": "sphs1p", "sbo": "SBO:0000247"}}, {"charge": 0, "name": "glucocerebroside ", "formula": "C43.5654H79.5778N1.0O8.0", "compartment": "c", "id": "gluside_ce_c", "annotation": {"bigg.metabolite": "gluside_hs", "sbo": "SBO:0000247"}}, {"charge": 0, "name": "galactocerebroside ", "formula": "C43.5654H79.5778N1.0O8.0", "compartment": "c", "id": "galside_ce_c", "annotation": {"bigg.metabolite": "galside_hs", "sbo": "SBO:0000247"}}, {"charge": -1, "name": "Phosphatidylserine", "formula": "C43.1308H74.1556N1.0O10.0P1.0", "compartment": "e", "id": "ps_e", "annotation": {"bigg.metabolite": ["ps181", "ps180", "ps161", "ps160", "ps141", "ps140", "ps120", "ps_SA", "ps_hs", "ps_EC", "ps_HP", "ps_SC"], "sbo": "SBO:0000247", "kegg.compound": "C02737"}}, {"charge": -1, "name": "tetradecanoate (n-C14:0)", "formula": "C14H27O2", "compartment": "e", "id": "ttdca_e", "annotation": {"bigg.metabolite": "ttdca", "sbo": "SBO:0000247", "kegg.compound": "C06424"}}, {"charge": 0, "name": "2-Decaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone", "formula": "C53H80O4", "compartment": "m", "id": "2npmhobq_m", "annotation": {"bigg.metabolite": "2dpmhobq", "sbo": "SBO:0000247"}}, {"charge": 0, "name": "2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinone", "formula": "C53H80O3", "compartment": "m", "id": "2np6mobq_me_m", "annotation": {"bigg.metabolite": "2dp6mobq_me", "sbo": "SBO:0000247"}}, {"charge": 0, "name": "Ubiquinone-8", "formula": "C49H74O4", "compartment": "m", "id": "q8_m", "annotation": {"bigg.metabolite": "q8", "sbo": "SBO:0000247"}}, {"charge": 0, "name": "Ubiquinone-9", "formula": "C54H82O4", "compartment": "m", "id": "q9_m", "annotation": {"bigg.metabolite": ["q8", "q6", "q10", "q"], "sbo": "SBO:0000247"}}, {"charge": 0, "name": "Methylglyoxal", "formula": "C3H4O2", "compartment": "m", "id": "mthgxl_m", "annotation": {"bigg.metabolite": "mthgxl", "sbo": "SBO:0000247", "kegg.compound": "C00546"}}, {"charge": -2, "name": "Bilirubin", "formula": "C33H34N4O6", "compartment": "e", "id": "bilirub_e", "annotation": {"bigg.metabolite": "bilirub", "sbo": "SBO:0000247", "kegg.compound": "C00486"}}, {"charge": -2, "name": "2-Acetyl-1-alkyl-sn-glycero-3-phosphate", "formula": "C23.0H45.0O7.0P1.0", "compartment": "c", "id": "acakgp_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C01264"}}, {"charge": 1, "name": "Tyramine", "formula": "C8H12NO", "compartment": "e", "id": "tym_e", "annotation": {"bigg.metabolite": "tym", "sbo": "SBO:0000247", "kegg.compound": "C00483"}}, {"charge": -1, "name": "2-Hydroxyphenylacetate", "formula": "C8H7O3", "compartment": "e", "id": "2hyoxplac_e", "annotation": {"bigg.metabolite": "2hyoxplac", "sbo": "SBO:0000247", "kegg.compound": "C05852"}}, {"charge": -4, "name": "Propenoyl-CoA", "formula": "C24H34N7O17P3S", "compartment": "m", "id": "prpncoa_m", "annotation": {"bigg.metabolite": "prpncoa", "sbo": "SBO:0000247", "kegg.compound": "C00894"}}, {"charge": 0, "name": "Pseudouridine", "formula": "C9H12N2O6", "compartment": "c", "id": "psduri_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C02067"}}, {"charge": 1, "name": "N6,N6,N6-Trimethyl-L-lysine", "formula": "C9H21N2O2", "compartment": "c", "id": "tmlys_c", "annotation": {"bigg.metabolite": "tmlys", "sbo": "SBO:0000247", "kegg.compound": "C03793"}}, {"charge": -2, "name": "Molybdate", "formula": "MoO4", "compartment": "e", "id": "mobd_e", "annotation": {"bigg.metabolite": "mobd", "sbo": "SBO:0000247", "kegg.compound": "C06232"}}, {"charge": -4, "name": "\"N6-(1,2-Dicarboxyethyl)-AMP\"", "formula": "C14H14N5O11P", "compartment": "c", "id": "dcamp_c", "annotation": {"bigg.metabolite": "dcamp", "sbo": "SBO:0000247", "kegg.compound": "C03794"}}, {"charge": 0, "name": "D-Mannose", "formula": "C6H12O6", "compartment": "c", "id": "man_c", "annotation": {"bigg.metabolite": "man", "sbo": "SBO:0000247", "kegg.compound": "C00159"}}, {"charge": -4, "name": "trans-Tetradec-2-enoyl-CoA", "formula": "C35H56N7O17P3S", "compartment": "c", "id": "td2coa_c", "annotation": {"bigg.metabolite": "td2coa", "sbo": "SBO:0000247", "kegg.compound": "C05273"}}, {"charge": 0, "name": "L-Glutamine", "formula": "C5H10N2O3", "compartment": "m", "id": "gln-L_m", "annotation": {"bigg.metabolite": "gln-L", "sbo": "SBO:0000247", "kegg.compound": "C00064"}}, {"charge": 0, "name": "L-Proline", "formula": "C5H9NO2", "compartment": "m", "id": "pro-L_m", "annotation": {"bigg.metabolite": "pro-L", "sbo": "SBO:0000247", "kegg.compound": "C00148"}}, {"charge": -1, "name": "N-Carbamoyl-beta-alanine", "formula": "C4H7N2O3", "compartment": "e", "id": "cala_e", "annotation": {"bigg.metabolite": "cala", "sbo": "SBO:0000247", "kegg.compound": "C02642"}}, {"charge": -3, "name": "UDP", "formula": "C9H11N2O12P2", "compartment": "c", "id": "udp_c", "annotation": {"bigg.metabolite": "udp", "sbo": "SBO:0000247", "kegg.compound": "C00015"}}, {"charge": -4, "name": "Octanoyl-CoA (n-C8:0CoA)", "formula": "C29H46N7O17P3S", "compartment": "m", "id": "occoa_m", "annotation": {"bigg.metabolite": "occoa", "sbo": "SBO:0000247", "kegg.compound": "C01944"}}, {"charge": 0, "name": "\"5,6-dihydrouracil\"", "formula": "C4H6N2O2", "compartment": "e", "id": "56dura_e", "annotation": {"bigg.metabolite": "56dura", "sbo": "SBO:0000247", "kegg.compound": "C00429"}}, {"charge": -4, "name": "Decanoyl-CoA (n-C10:0CoA)", "formula": "C31H50N7O17P3S", "compartment": "c", "id": "dcacoa_c", "annotation": {"bigg.metabolite": "dcacoa", "sbo": "SBO:0000247", "kegg.compound": "C05274"}}, {"charge": -1, "name": "4-Hydroxybenzoate", "formula": "C7H5O3", "compartment": "c", "id": "4hbz_c", "annotation": {"bigg.metabolite": "4hbz", "sbo": "SBO:0000247", "kegg.compound": "C00156"}}, {"charge": 0, "name": "Deoxyuridine", "formula": "C9H12N2O5", "compartment": "c", "id": "duri_c", "annotation": {"bigg.metabolite": "duri", "sbo": "SBO:0000247", "kegg.compound": "C00526"}}, {"charge": 0, "name": "Androsterone", "formula": "C19H30O2", "compartment": "c", "id": "andrstrn_c", "annotation": {"bigg.metabolite": "andrstrn", "sbo": "SBO:0000247", "kegg.compound": "C00523"}}, {"charge": -1, "name": "(R)-Pantothenate", "formula": "C9H16NO5", "compartment": "e", "id": "pnto-R_e", "annotation": {"bigg.metabolite": "pnto-R", "sbo": "SBO:0000247", "kegg.compound": "C00864"}}, {"charge": -1, "name": "gamma-Glutamyl-beta-cyanoalanine", "formula": "C9H12N3O5", "compartment": "c", "id": "gcynala_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C05711"}}, {"charge": -1, "name": "\"3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoate\"", "formula": "C27H45O5", "compartment": "e", "id": "thcholstoic_e", "annotation": {"bigg.metabolite": "thcholstoic", "sbo": "SBO:0000247", "kegg.compound": "C04722"}}, {"charge": -1, "name": "5-Hydroxyindoleacetate", "formula": "C10H8NO3", "compartment": "e", "id": "5hoxindoa_e", "annotation": {"bigg.metabolite": "5hoxindoa", "sbo": "SBO:0000247", "kegg.compound": "C05635"}}, {"charge": 0, "name": "L-3-Amino-isobutanoate", "formula": "C4H9NO2", "compartment": "e", "id": "3aib_e", "annotation": {"bigg.metabolite": "3aib", "sbo": "SBO:0000247", "kegg.compound": "C03284"}}, {"charge": 1, "name": "Serotonin", "formula": "C10H13N2O", "compartment": "c", "id": "srtn_c", "annotation": {"bigg.metabolite": "srtn", "sbo": "SBO:0000247", "kegg.compound": "C00780"}}, {"charge": -1, "name": "Urocanate", "formula": "C6H5N2O2", "compartment": "c", "id": "urcan_c", "annotation": {"bigg.metabolite": "urcan", "sbo": "SBO:0000247", "kegg.compound": "C00785"}}, {"charge": 0, "name": "tRNA(Tyr)", "formula": "ROH", "compartment": "c", "id": "trnatyr_c", "annotation": {"bigg.metabolite": "trnatyr", "sbo": "SBO:0000247", "kegg.compound": "C00787"}}, {"charge": 1, "name": "potassium", "formula": "K", "compartment": "c", "id": "k_c", "annotation": {"bigg.metabolite": "k", "sbo": "SBO:0000247", "kegg.compound": "C00238"}}, {"charge": -2, "name": "dCMP", "formula": "C9H12N3O7P", "compartment": "c", "id": "dcmp_c", "annotation": {"bigg.metabolite": "dcmp", "sbo": "SBO:0000247", "kegg.compound": "C00239"}}, {"charge": -2, "name": "D-Xylulose 5-phosphate", "formula": "C5H9O8P", "compartment": "c", "id": "xu5p-D_c", "annotation": {"bigg.metabolite": "xu5p-D", "sbo": "SBO:0000247", "kegg.compound": "C00231"}}, {"charge": -1, "name": "Succinic semialdehyde", "formula": "C4H5O3", "compartment": "c", "id": "sucsal_c", "annotation": {"bigg.metabolite": "sucsal", "sbo": "SBO:0000247", "kegg.compound": "C00232"}}, {"charge": -1, "name": "4-Methyl-2-oxopentanoate", "formula": "C6H9O3", "compartment": "c", "id": "4mop_c", "annotation": {"bigg.metabolite": "4mop", "sbo": "SBO:0000247", "kegg.compound": "C00233"}}, {"charge": -2, "name": "10-Formyltetrahydrofolate", "formula": "C20H21N7O7", "compartment": "c", "id": "10fthf_c", "annotation": {"bigg.metabolite": "10fthf", "sbo": "SBO:0000247", "kegg.compound": "C00234"}}, {"charge": -3, "name": "Dimethylallyl diphosphate", "formula": "C5H9O7P2", "compartment": "c", "id": "dmpp_c", "annotation": {"bigg.metabolite": "dmpp", "sbo": "SBO:0000247", "kegg.compound": "C00235"}}, {"charge": -4, "name": "3-Phospho-D-glyceroyl phosphate", "formula": "C3H4O10P2", "compartment": "c", "id": "13dpg_c", "annotation": {"bigg.metabolite": "13dpg", "sbo": "SBO:0000247", "kegg.compound": "C00236"}}, {"charge": -4, "name": "Coenzyme A", "formula": "C21H32N7O16P3S", "compartment": "c", "id": "coa_c", "annotation": {"bigg.metabolite": "coa", "sbo": "SBO:0000247", "kegg.compound": "C00010"}}, {"charge": 0, "name": "CO2", "formula": "CO2", "compartment": "c", "id": "co2_c", "annotation": {"bigg.metabolite": "co2", "sbo": "SBO:0000247", "kegg.compound": "C00011"}}, {"charge": 0, "name": "Peptide", "formula": "C2H4NO2R(C2H2NOR)n", "compartment": "c", "id": "pepd_c", "annotation": {"bigg.metabolite": "pepd", "sbo": "SBO:0000247", "kegg.compound": "C00012"}}, {"charge": -3, "name": "Diphosphate", "formula": "HO7P2", "compartment": "c", "id": "ppi_c", "annotation": {"bigg.metabolite": "ppi", "sbo": "SBO:0000247", "kegg.compound": "C00013"}}, {"charge": 1, "name": "Ammonium", "formula": "H4N", "compartment": "c", "id": "nh4_c", "annotation": {"bigg.metabolite": "nh4", "sbo": "SBO:0000247", "kegg.compound": "C00014"}}, {"charge": -2, "name": "L-Malate", "formula": "C4H4O5", "compartment": "m", "id": "mal-L_m", "annotation": {"bigg.metabolite": "mal-L", "sbo": "SBO:0000247", "kegg.compound": "C00149"}}, {"charge": -2, "name": "Flavin adenine dinucleotide oxidized", "formula": "C27H31N9O15P2", "compartment": "c", "id": "fad_c", "annotation": {"bigg.metabolite": "fad", "sbo": "SBO:0000247", "kegg.compound": "C00016"}}, {"charge": -2, "name": "Pyridoxal 5'-phosphate", "formula": "C8H8NO6P", "compartment": "c", "id": "pydx5p_c", "annotation": {"bigg.metabolite": "pydx5p", "sbo": "SBO:0000247", "kegg.compound": "C00018"}}, {"charge": 1, "name": "S-Adenosyl-L-methionine", "formula": "C15H23N6O5S", "compartment": "c", "id": "amet_c", "annotation": {"bigg.metabolite": "amet", "sbo": "SBO:0000247", "kegg.compound": "C00019"}}, {"charge": 0, "name": "Adenine", "formula": "C5H5N5", "compartment": "m", "id": "ade_m", "annotation": {"bigg.metabolite": "ade", "sbo": "SBO:0000247", "kegg.compound": "C00147"}}, {"charge": -1, "name": "3-Methyl-2-oxobutanoate", "formula": "C5H7O3", "compartment": "m", "id": "3mob_m", "annotation": {"bigg.metabolite": "3mob", "sbo": "SBO:0000247", "kegg.compound": "C00141"}}, {"charge": -2, "name": "\"5,10-Methylenetetrahydrofolate\"", "formula": "C20H21N7O6", "compartment": "m", "id": "mlthf_m", "annotation": {"bigg.metabolite": "mlthf", "sbo": "SBO:0000247", "kegg.compound": "C00143"}}, {"charge": -2, "name": "Phosphate", "formula": "HO4P", "compartment": "e", "id": "pi_e", "annotation": {"bigg.metabolite": "pi", "sbo": "SBO:0000247", "kegg.compound": "C00009"}}, {"charge": -3, "name": "all-trans-Nonaprenyl diphosphate", "formula": "C45H73O7P2", "compartment": "c", "id": "nonadp_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C04145"}}, {"charge": 0, "name": "H2O", "formula": "H2O", "compartment": "e", "id": "h2o_e", "annotation": {"bigg.metabolite": "h2o", "sbo": "SBO:0000247", "kegg.compound": "C00001"}}, {"charge": -4, "name": "ATP", "formula": "C10H12N5O13P3", "compartment": "e", "id": "atp_e", "annotation": {"bigg.metabolite": "atp", "sbo": "SBO:0000247", "kegg.compound": "C00002"}}, {"charge": 0, "name": "O2", "formula": "O2", "compartment": "e", "id": "o2_e", "annotation": {"bigg.metabolite": "o2", "sbo": "SBO:0000247", "kegg.compound": "C00007"}}, {"charge": -1, "name": "CDPcholine", "formula": "C14H25N4O11P2", "compartment": "c", "id": "cdpchol_c", "annotation": {"bigg.metabolite": "cdpchol", "sbo": "SBO:0000247", "kegg.compound": "C00307"}}, {"charge": -2, "name": "ADPribose", "formula": "C15H21N5O14P2", "compartment": "c", "id": "adprib_c", "annotation": {"bigg.metabolite": "adprib", "sbo": "SBO:0000247", "kegg.compound": "C00301"}}, {"charge": 0, "name": "\"3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-al\"", "formula": "C27H46O4", "compartment": "m", "id": "thcholst_m", "annotation": {"bigg.metabolite": "thcholst", "sbo": "SBO:0000247", "kegg.compound": "C01301"}}, {"charge": -4, "name": "\"3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoyl-CoA(S)\"", "formula": "C48H76N7O20P3S", "compartment": "c", "id": "cholcoas_c", "annotation": {"bigg.metabolite": "cholcoas", "sbo": "SBO:0000247", "kegg.compound": "C17343"}}, {"charge": 0, "name": "Peptide 2-(3-carboxy-3-aminopropyl)-L-histidine", "formula": "C11H15N5O4R2", "compartment": "c", "id": "caphis_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C04441"}}, {"charge": 0, "name": "7alpha-Hydroxycholest-4-en-3-one", "formula": "C27H44O2", "compartment": "e", "id": "xol7aone_e", "annotation": {"bigg.metabolite": "xol7aone", "sbo": "SBO:0000247", "kegg.compound": "C05455"}}, {"charge": 2, "name": "Putrescine", "formula": "C4H14N2", "compartment": "e", "id": "ptrc_e", "annotation": {"bigg.metabolite": "ptrc", "sbo": "SBO:0000247", "kegg.compound": "C00134"}}, {"charge": 0, "name": "O-Acetylcarnitine", "formula": "C9H17NO4", "compartment": "m", "id": "acrn_m", "annotation": {"bigg.metabolite": "acrn", "sbo": "SBO:0000247", "kegg.compound": "C02571"}}, {"charge": 0, "name": "beta-Alanine", "formula": "C3H7NO2", "compartment": "m", "id": "ala-B_m", "annotation": {"bigg.metabolite": "ala-B", "sbo": "SBO:0000247", "kegg.compound": "C00099"}}, {"charge": -2, "name": "IMP", "formula": "C10H11N4O8P", "compartment": "e", "id": "imp_e", "annotation": {"bigg.metabolite": "imp", "sbo": "SBO:0000247", "kegg.compound": "C00130"}}, {"charge": 0, "name": "D-Alanine", "formula": "C3H7NO2", "compartment": "e", "id": "ala-D_e", "annotation": {"bigg.metabolite": "ala-D", "sbo": "SBO:0000247", "kegg.compound": "C00133"}}, {"charge": 0, "name": "Methanol", "formula": "CH4O1", "compartment": "e", "id": "meoh_e", "annotation": {"bigg.metabolite": "meoh", "sbo": "SBO:0000247", "kegg.compound": "C00132"}}, {"charge": -2, "name": "Glycerol 3-phosphate", "formula": "C3H7O6P", "compartment": "m", "id": "glyc3p_m", "annotation": {"bigg.metabolite": "glyc3p", "sbo": "SBO:0000247", "kegg.compound": "C00093"}}, {"charge": -5, "name": "Succinyl-CoA", "formula": "C25H35N7O19P3S", "compartment": "m", "id": "succoa_m", "annotation": {"bigg.metabolite": "succoa", "sbo": "SBO:0000247", "kegg.compound": "C00091"}}, {"charge": 0, "name": "L-Cysteine", "formula": "C3H7NO2S", "compartment": "m", "id": "cys-L_m", "annotation": {"bigg.metabolite": "cys-L", "sbo": "SBO:0000247", "kegg.compound": "C00097"}}, {"charge": -2, "name": "Sulfite", "formula": "O3S", "compartment": "m", "id": "so3_m", "annotation": {"bigg.metabolite": "so3", "sbo": "SBO:0000247", "kegg.compound": "C00094"}}, {"charge": -2, "name": "Xanthosine 5'-phosphate", "formula": "C10H11N4O9P", "compartment": "c", "id": "xmp_c", "annotation": {"bigg.metabolite": "xmp", "sbo": "SBO:0000247", "kegg.compound": "C00655"}}, {"charge": -2, "name": "N,N'-Diacetylchitobiosyldiphosphodolichol", "formula": "C126H206N2O17P2", "compartment": "c", "id": "chito2pdol_c", "annotation": {"bigg.metabolite": ["chito2pdol_L", "chito2pdol_U"], "sbo": "SBO:0000247", "kegg.compound": "C04537"}}, {"charge": -1, "name": "3-Hydroxypropanoate", "formula": "C3H5O3", "compartment": "c", "id": "3hpp_c", "annotation": {"bigg.metabolite": "3hpp", "sbo": "SBO:0000247", "kegg.compound": "C01013"}}, {"charge": -2, "name": "2-Oxoadipate", "formula": "C6H6O5", "compartment": "m", "id": "2oxoadp_m", "annotation": {"bigg.metabolite": "2oxoadp", "sbo": "SBO:0000247", "kegg.compound": "C00322"}}, {"charge": 0, "name": "L-Fucose", "formula": "C6H12O5", "compartment": "c", "id": "fuc-L_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C01019"}}, {"charge": 0, "name": "L-Arabinose", "formula": "C5H10O5", "compartment": "e", "id": "arab-L_e", "annotation": {"bigg.metabolite": "arab-L", "sbo": "SBO:0000247", "kegg.compound": "C00259"}}, {"charge": 0, "name": "Pyridoxal", "formula": "C8H9NO3", "compartment": "e", "id": "pydx_e", "annotation": {"bigg.metabolite": "pydx", "sbo": "SBO:0000247", "kegg.compound": "C00250"}}, {"charge": -1, "name": "Nicotinate", "formula": "C6H4NO2", "compartment": "e", "id": "nac_e", "annotation": {"bigg.metabolite": "nac", "sbo": "SBO:0000247", "kegg.compound": "C00253"}}, {"charge": 0, "name": "Riboflavin", "formula": "C17H20N4O6", "compartment": "e", "id": "ribflv_e", "annotation": {"bigg.metabolite": "ribflv", "sbo": "SBO:0000247", "kegg.compound": "C00255"}}, {"charge": -1, "name": "D-Lactate", "formula": "C3H5O3", "compartment": "e", "id": "lac-D_e", "annotation": {"bigg.metabolite": "lac-D", "sbo": "SBO:0000247", "kegg.compound": "C00256"}}, {"charge": -1, "name": "D-Gluconate", "formula": "C6H11O7", "compartment": "e", "id": "glcn_e", "annotation": {"bigg.metabolite": "glcn", "sbo": "SBO:0000247", "kegg.compound": "C00257"}}, {"charge": -1, "name": "(S)-3-Hydroxybutanoate", "formula": "C4H7O3", "compartment": "m", "id": "S3hb_m", "annotation": {"bigg.metabolite": "bhb", "sbo": "SBO:0000247", "kegg.compound": "C03197"}}, {"charge": 0, "name": "tRNA(Thr)", "formula": "ROH", "compartment": "c", "id": "trnathr_c", "annotation": {"bigg.metabolite": "trnathr", "sbo": "SBO:0000247", "kegg.compound": "C01651"}}, {"charge": 0, "name": "tRNA(Ser)", "formula": "ROH", "compartment": "c", "id": "trnaser_c", "annotation": {"bigg.metabolite": "trnaser", "sbo": "SBO:0000247", "kegg.compound": "C01650"}}, {"charge": 0, "name": "\"3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestan-26-al\"", "formula": "C27H46O4", "compartment": "c", "id": "thcholst_c", "annotation": {"bigg.metabolite": "thcholst", "sbo": "SBO:0000247", "kegg.compound": "C01301"}}, {"charge": 0, "name": "tRNA(Trp)", "formula": "ROH", "compartment": "c", "id": "trnatrp_c", "annotation": {"bigg.metabolite": "trnatrp", "sbo": "SBO:0000247", "kegg.compound": "C01652"}}, {"charge": -2, "name": "Xanthurenic acid", "formula": "C10H5NO4", "compartment": "c", "id": "xanate_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C02470"}}, {"charge": -1, "name": "Phytochelatin", "formula": "C2H5NO2(C8H11N2O4S)n", "compartment": "c", "id": "pchltn_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C02471"}}, {"charge": -4, "name": "trans-Dodec-2-enoyl-CoA", "formula": "C33H52N7O17P3S", "compartment": "m", "id": "dd2coa_m", "annotation": {"bigg.metabolite": "dd2coa", "sbo": "SBO:0000247", "kegg.compound": "C03221"}}, {"charge": -1, "name": "5-Oxoproline", "formula": "C5H6NO3", "compartment": "c", "id": "5oxpro_c", "annotation": {"bigg.metabolite": "5oxpro", "sbo": "SBO:0000247", "kegg.compound": "C01879"}}, {"charge": -3, "name": "1-Phosphatidyl-1D-myo-inositol 4-phosphate ", "formula": "C46.1308H78.1556O16.0P2.0", "compartment": "c", "id": "pail4p_c", "annotation": {"bigg.metabolite": "pail4p_hs", "sbo": "SBO:0000247", "kegg.compound": "C01277"}}, {"charge": -8, "name": "\"1D-myo-Inositol 1,3,4,5-tetrakisphosphate\"", "formula": "C6H8O18P4", "compartment": "c", "id": "mi1345p_c", "annotation": {"bigg.metabolite": "mi1345p", "sbo": "SBO:0000247", "kegg.compound": "C01272"}}, {"charge": -2, "name": "Dephospho-CoA", "formula": "C21H33N7O13P2S", "compartment": "m", "id": "dpcoa_m", "annotation": {"bigg.metabolite": "dpcoa", "sbo": "SBO:0000247", "kegg.compound": "C00882"}}, {"charge": 1, "name": "L-Alanyl-tRNA(Ala)", "formula": "C3H7NO2R", "compartment": "m", "id": "alatrna_m", "annotation": {"bigg.metabolite": "alatrna", "sbo": "SBO:0000247", "kegg.compound": "C00886"}}, {"charge": 0, "name": "Dihydrolipolprotein", "formula": "H2S2X", "compartment": "m", "id": "dhlpro_m", "annotation": {"bigg.metabolite": "dhlpro", "sbo": "SBO:0000247", "kegg.compound": "C02972"}}, {"charge": 0, "name": "Stachyose", "formula": "C24H42O21", "compartment": "e", "id": "stachyose_e", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C01613"}}, {"charge": 0, "name": "beta-Carotene", "formula": "C40H56", "compartment": "c", "id": "caro_c", "annotation": {"bigg.metabolite": "caro", "sbo": "SBO:0000247", "kegg.compound": "C02094"}}, {"charge": -2, "name": "UDP-4-keto-6-deoxy-D-glucose", "formula": "C15H20N2O16P2", "compartment": "c", "id": "udp4k6dg_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C04089"}}, {"charge": -1, "name": "Peptide L-aspartate", "formula": "XC4H4NO3", "compartment": "c", "id": "pepasp_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C02871"}}, {"charge": 0, "name": "L-Histidine", "formula": "C6H9N3O2", "compartment": "e", "id": "his-L_e", "annotation": {"bigg.metabolite": "his-L", "sbo": "SBO:0000247", "kegg.compound": "C00135"}}, {"charge": -1, "name": "Dodecanoate (n-C12:0)", "formula": "C12H23O2", "compartment": "e", "id": "ddca_e", "annotation": {"bigg.metabolite": "ddca", "sbo": "SBO:0000247", "kegg.compound": "C02679"}}, {"charge": 0, "name": "sedoheptulose", "formula": "C7H14O7", "compartment": "e", "id": "sedh_e", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C02076"}}, {"charge": 2, "name": "L-Lysine-tRNA (Lys)", "formula": "C6H15N2O2R", "compartment": "m", "id": "lystrna_m", "annotation": {"bigg.metabolite": "lystrna", "sbo": "SBO:0000247", "kegg.compound": "C01931"}}, {"charge": -2, "name": "5-Formyltetrahydrofolate", "formula": "C20H21N7O7", "compartment": "e", "id": "5fthf_e", "annotation": {"bigg.metabolite": "5fthf", "sbo": "SBO:0000247", "kegg.compound": "C03479"}}, {"charge": -1, "name": "11,12-EET", "formula": "C20H31O3", "compartment": "c", "id": "eet_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C14770"}}, {"charge": -1, "name": "2-Methyl-3-oxopropanoate", "formula": "C4H5O3", "compartment": "m", "id": "2mop_m", "annotation": {"bigg.metabolite": "2mop", "sbo": "SBO:0000247", "kegg.compound": "C06002"}}, {"charge": -1, "name": "3-Hydroxy-2-methylpropanoate", "formula": "C4H7O3", "compartment": "m", "id": "3hmp_m", "annotation": {"bigg.metabolite": "3hmp", "sbo": "SBO:0000247", "kegg.compound": "C06001"}}, {"charge": -4, "name": "(S)-3-Hydroxyisobutyryl-CoA", "formula": "C25H38N7O18P3S", "compartment": "m", "id": "3hibutcoa_m", "annotation": {"bigg.metabolite": "3hibutcoa", "sbo": "SBO:0000247", "kegg.compound": "C06000"}}, {"charge": 3, "name": "Fe3+", "formula": "Fe", "compartment": "c", "id": "fe3_c", "annotation": {"bigg.metabolite": "fe3", "sbo": "SBO:0000247", "kegg.compound": "C14819"}}, {"charge": 2, "name": "Fe2+", "formula": "Fe", "compartment": "c", "id": "fe2_c", "annotation": {"bigg.metabolite": "fe2", "sbo": "SBO:0000247", "kegg.compound": "C14818"}}, {"charge": 1, "name": "L-Tryptophanyl-tRNA(Trp)", "formula": "C11H12N2O2R", "compartment": "m", "id": "trptrna_m", "annotation": {"bigg.metabolite": "trptrna", "sbo": "SBO:0000247", "kegg.compound": "C03512"}}, {"charge": 0, "name": "L-Arabinitol", "formula": "C5H12O5", "compartment": "c", "id": "abt_c", "annotation": {"bigg.metabolite": "abt", "sbo": "SBO:0000247", "kegg.compound": "C00532"}}, {"charge": 1, "name": "L-Phenylalanyl-tRNA(Phe)", "formula": "C9H11NO2R", "compartment": "m", "id": "phetrna_m", "annotation": {"bigg.metabolite": "phetrna", "sbo": "SBO:0000247", "kegg.compound": "C03511"}}, {"charge": -4, "name": "Inorganic triphosphate", "formula": "HO10P3", "compartment": "c", "id": "pppi_c", "annotation": {"bigg.metabolite": "pppi", "sbo": "SBO:0000247", "kegg.compound": "C00536"}}, {"charge": 0, "name": "Testosterone", "formula": "C19H28O2", "compartment": "c", "id": "tststerone_c", "annotation": {"bigg.metabolite": "tststerone", "sbo": "SBO:0000247", "kegg.compound": "C00535"}}, {"charge": 1, "name": "Pyridoxamine", "formula": "C8H13N2O2", "compartment": "c", "id": "pydam_c", "annotation": {"bigg.metabolite": "pydam", "sbo": "SBO:0000247", "kegg.compound": "C00534"}}, {"charge": 0, "name": "\"7-alpha,27-Dihydroxycholesterol\"", "formula": "C27H46O3", "compartment": "e", "id": "xoltri27_e", "annotation": {"bigg.metabolite": "xoltri27", "sbo": "SBO:0000247", "kegg.compound": "C06341"}}, {"charge": -1, "name": "trans-4-Hydroxycinnamate", "formula": "C9H7O3", "compartment": "e", "id": "T4hcinnm_e", "annotation": {"bigg.metabolite": "T4hcinnm", "sbo": "SBO:0000247", "kegg.compound": "C00811"}}, {"charge": -2, "name": "D-Glucarate", "formula": "C6H8O8", "compartment": "e", "id": "glcr_e", "annotation": {"bigg.metabolite": "glcr", "sbo": "SBO:0000247", "kegg.compound": "C00818"}}, {"charge": 0, "name": "D-Sorbitol", "formula": "C6H14O6", "compartment": "c", "id": "sbt-D_c", "annotation": {"bigg.metabolite": "sbt-D", "sbo": "SBO:0000247", "kegg.compound": "C00794"}}, {"charge": -2, "name": "Adenosine 5'-phosphosulfate", "formula": "C10H12N5O10PS", "compartment": "c", "id": "aps_c", "annotation": {"bigg.metabolite": "aps", "sbo": "SBO:0000247", "kegg.compound": "C00224"}}, {"charge": -4, "name": "4-Coumaroyl-CoA", "formula": "C30H38N7O18P3S", "compartment": "c", "id": "4cmcoa_c", "annotation": {"bigg.metabolite": "4cmcoa", "sbo": "SBO:0000247", "kegg.compound": "C00223"}}, {"charge": 0, "name": "beta-D-Glucose", "formula": "C6H12O6", "compartment": "c", "id": "glc-D-B_c", "annotation": {"bigg.metabolite": "glc-D", "sbo": "SBO:0000247", "kegg.compound": "C00221"}}, {"charge": 2, "name": "L-Arginyl-tRNA(Arg)", "formula": "C6H15N4O2R", "compartment": "m", "id": "argtrna_m", "annotation": {"bigg.metabolite": "argtrna", "sbo": "SBO:0000247", "kegg.compound": "C02163"}}, {"charge": -1, "name": "Ascaroside 7", "formula": "C13H21O6", "compartment": "e", "id": "ascr7_e", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -3, "name": "Citrate", "formula": "C6H5O7", "compartment": "m", "id": "cit_m", "annotation": {"bigg.metabolite": "cit", "sbo": "SBO:0000247", "kegg.compound": "C00158"}}, {"charge": -2, "name": "Phosphate", "formula": "HO4P", "compartment": "c", "id": "pi_c", "annotation": {"bigg.metabolite": "pi", "sbo": "SBO:0000247", "kegg.compound": "C00009"}}, {"charge": -3, "name": "ADP", "formula": "C10H12N5O10P2", "compartment": "c", "id": "adp_c", "annotation": {"bigg.metabolite": "adp", "sbo": "SBO:0000247", "kegg.compound": "C00008"}}, {"charge": 0, "name": "O2", "formula": "O2", "compartment": "c", "id": "o2_c", "annotation": {"bigg.metabolite": "o2", "sbo": "SBO:0000247", "kegg.compound": "C00007"}}, {"charge": 0, "name": "L-Asparagine", "formula": "C4H8N2O3", "compartment": "m", "id": "asn-L_m", "annotation": {"bigg.metabolite": "asn-L", "sbo": "SBO:0000247", "kegg.compound": "C00152"}}, {"charge": -4, "name": "Nicotinamide adenine dinucleotide phosphate - reduced", "formula": "C21H26N7O17P3", "compartment": "c", "id": "nadph_c", "annotation": {"bigg.metabolite": "nadph", "sbo": "SBO:0000247", "kegg.compound": "C00005"}}, {"charge": -2, "name": "Nicotinamide adenine dinucleotide - reduced", "formula": "C21H27N7O14P2", "compartment": "c", "id": "nadh_c", "annotation": {"bigg.metabolite": "nadh", "sbo": "SBO:0000247", "kegg.compound": "C00004"}}, {"charge": -1, "name": "Nicotinamide adenine dinucleotide", "formula": "C21H26N7O14P2", "compartment": "c", "id": "nad_c", "annotation": {"bigg.metabolite": "nad", "sbo": "SBO:0000247", "kegg.compound": "C00003"}}, {"charge": -4, "name": "ATP", "formula": "C10H12N5O13P3", "compartment": "c", "id": "atp_c", "annotation": {"bigg.metabolite": "atp", "sbo": "SBO:0000247", "kegg.compound": "C00002"}}, {"charge": 0, "name": "H2O", "formula": "H2O", "compartment": "c", "id": "h2o_c", "annotation": {"bigg.metabolite": "h2o", "sbo": "SBO:0000247", "kegg.compound": "C00001"}}, {"charge": -4, "name": "Palmitoyl-CoA (n-C16:0CoA)", "formula": "C37H62N7O17P3S", "compartment": "m", "id": "pmtcoa_m", "annotation": {"bigg.metabolite": "pmtcoa", "sbo": "SBO:0000247", "kegg.compound": "C00154"}}, {"charge": 0, "name": "Glycine", "formula": "C2H5NO2", "compartment": "e", "id": "gly_e", "annotation": {"bigg.metabolite": "gly", "sbo": "SBO:0000247", "kegg.compound": "C00037"}}, {"charge": 0, "name": "D-Glucose", "formula": "C6H12O6", "compartment": "e", "id": "glc-D_e", "annotation": {"bigg.metabolite": "glc-D", "sbo": "SBO:0000247", "kegg.compound": "C00031"}}, {"charge": 0, "name": "Protoheme", "formula": "C34H30FeN4O4", "compartment": "e", "id": "pheme_e", "annotation": {"bigg.metabolite": "pheme", "sbo": "SBO:0000247", "kegg.compound": "C00032"}}, {"charge": -1, "name": "Acetate", "formula": "C2H3O2", "compartment": "e", "id": "ac_e", "annotation": {"bigg.metabolite": "ac", "sbo": "SBO:0000247", "kegg.compound": "C00033"}}, {"charge": 0, "name": "L-Allo-threonine", "formula": "C4H9NO3", "compartment": "e", "id": "athr-L_e", "annotation": {"bigg.metabolite": "athr-L", "sbo": "SBO:0000247", "kegg.compound": "C05519"}}, {"charge": -2, "name": "L-sulfolactate", "formula": "C3H4O6S", "compartment": "e", "id": "sl-L_e", "annotation": {"bigg.metabolite": "sl-L", "sbo": "SBO:0000247", "kegg.compound": "C11499"}}, {"charge": 0, "name": "L-Xylulose", "formula": "C5H10O5", "compartment": "c", "id": "xylu-L_c", "annotation": {"bigg.metabolite": "xylu-L", "sbo": "SBO:0000247", "kegg.compound": "C00312"}}, {"charge": -3, "name": "Isocitrate", "formula": "C6H5O7", "compartment": "c", "id": "icit_c", "annotation": {"bigg.metabolite": "icit", "sbo": "SBO:0000247", "kegg.compound": "C00311"}}, {"charge": 0, "name": "D-Xylulose", "formula": "C5H10O5", "compartment": "c", "id": "xylu-D_c", "annotation": {"bigg.metabolite": "xylu-D", "sbo": "SBO:0000247", "kegg.compound": "C00310"}}, {"charge": 0, "name": "diacylglycerol (phospholipids)", "formula": "C40.1308H69.1556O5.0", "compartment": "c", "id": "dag_pl_c", "annotation": {"bigg.metabolite": "dag_hs", "sbo": "SBO:0000247", "kegg.compound": "C00641"}}, {"charge": 3, "name": "Spermidine", "formula": "C7H22N3", "compartment": "c", "id": "spmd_c", "annotation": {"bigg.metabolite": "spmd", "sbo": "SBO:0000247", "kegg.compound": "C00315"}}, {"charge": 0, "name": "Pyridoxine", "formula": "C8H11NO3", "compartment": "c", "id": "pydxn_c", "annotation": {"bigg.metabolite": "pydxn", "sbo": "SBO:0000247", "kegg.compound": "C00314"}}, {"charge": 0, "name": "L-Carnitine", "formula": "C7H15NO3", "compartment": "c", "id": "crn_c", "annotation": {"bigg.metabolite": "crn", "sbo": "SBO:0000247", "kegg.compound": "C00318"}}, {"charge": -1, "name": "Selenophosphate", "formula": "H2O3PSe", "compartment": "c", "id": "selnp_c", "annotation": {"bigg.metabolite": "selnp", "sbo": "SBO:0000247", "kegg.compound": "C05172"}}, {"charge": -2, "name": "\"5,6,7,8-Tetrahydrofolate\"", "formula": "C19H21N7O6", "compartment": "e", "id": "thf_e", "annotation": {"bigg.metabolite": "thf", "sbo": "SBO:0000247", "kegg.compound": "C00101"}}, {"charge": 0, "name": "Uracil", "formula": "C4H4N2O2", "compartment": "e", "id": "ura_e", "annotation": {"bigg.metabolite": "ura", "sbo": "SBO:0000247", "kegg.compound": "C00106"}}, {"charge": -1, "name": "Anthranilate", "formula": "C7H6NO2", "compartment": "e", "id": "anth_e", "annotation": {"bigg.metabolite": "anth", "sbo": "SBO:0000247", "kegg.compound": "C00108"}}, {"charge": -1, "name": "2-Oxobutanoate", "formula": "C4H5O3", "compartment": "e", "id": "2obut_e", "annotation": {"bigg.metabolite": "2obut", "sbo": "SBO:0000247", "kegg.compound": "C00109"}}, {"charge": 0, "name": "L-Tyrosine", "formula": "C9H11NO3", "compartment": "m", "id": "tyr-L_m", "annotation": {"bigg.metabolite": "tyr-L", "sbo": "SBO:0000247", "kegg.compound": "C00082"}}, {"charge": 0, "name": "Acetaldehyde", "formula": "C2H4O", "compartment": "m", "id": "acald_m", "annotation": {"bigg.metabolite": "acald", "sbo": "SBO:0000247", "kegg.compound": "C00084"}}, {"charge": 0, "name": "Sulfur", "formula": "S", "compartment": "m", "id": "s_m", "annotation": {"bigg.metabolite": "s", "sbo": "SBO:0000247", "kegg.compound": "C00087"}}, {"charge": -2, "name": "Thiosulfate", "formula": "O3S2", "compartment": "m", "id": "tsul_m", "annotation": {"bigg.metabolite": "tsul", "sbo": "SBO:0000247", "kegg.compound": "C00320"}}, {"charge": -4, "name": "Acetoacetyl-CoA", "formula": "C25H36N7O18P3S", "compartment": "m", "id": "aacoa_m", "annotation": {"bigg.metabolite": "aacoa", "sbo": "SBO:0000247", "kegg.compound": "C00332"}}, {"charge": 0, "name": "N4-(Acetyl-beta-D-glucosaminyl)asparagine", "formula": "C12H21N3O8", "compartment": "c", "id": "acBgamamAsn_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C04540"}}, {"charge": -2, "name": "4-Fumarylacetoacetate", "formula": "C8H6O6", "compartment": "c", "id": "4fumacac_c", "annotation": {"bigg.metabolite": "4fumacac", "sbo": "SBO:0000247", "kegg.compound": "C01061"}}, {"charge": 0, "name": "Lactose", "formula": "C12H22O11", "compartment": "e", "id": "lcts_e", "annotation": {"bigg.metabolite": "lcts", "sbo": "SBO:0000247", "kegg.compound": "C00243"}}, {"charge": 0, "name": "Guanine", "formula": "C5H5N5O", "compartment": "e", "id": "gua_e", "annotation": {"bigg.metabolite": "gua", "sbo": "SBO:0000247", "kegg.compound": "C00242"}}, {"charge": 0, "name": "4-Aminobutanoate", "formula": "C4H9NO2", "compartment": "m", "id": "4abut_m", "annotation": {"bigg.metabolite": "4abut", "sbo": "SBO:0000247", "kegg.compound": "C00334"}}, {"charge": -3, "name": "1-Phosphatidyl-1D-myo-inositol 3-phosphate ", "formula": "C46.1308H78.1556O16.0P2.0", "compartment": "c", "id": "pail3p_c", "annotation": {"bigg.metabolite": "pail3p_hs", "sbo": "SBO:0000247", "kegg.compound": "C04549"}}, {"charge": 0, "name": "D-3-Amino-isobutanoate", "formula": "C4H9NO2", "compartment": "m", "id": "3aib-D_m", "annotation": {"bigg.metabolite": "3aib-D", "sbo": "SBO:0000247", "kegg.compound": "C01205"}}, {"charge": -1, "name": "Hexadecanoate (n-C16:0)", "formula": "C16H31O2", "compartment": "e", "id": "hdca_e", "annotation": {"bigg.metabolite": "hdca", "sbo": "SBO:0000247", "kegg.compound": "C00249"}}, {"charge": -4, "name": "trans-2-Methylbut-2-enoyl-CoA", "formula": "C26H38N7O17P3S", "compartment": "m", "id": "2mb2coa_m", "annotation": {"bigg.metabolite": "2mb2coa", "sbo": "SBO:0000247", "kegg.compound": "C03345"}}, {"charge": -4, "name": "2-Methyl-3-acetoacetyl-CoA", "formula": "C26H38N7O18P3S", "compartment": "m", "id": "2maacoa_m", "annotation": {"bigg.metabolite": "2maacoa", "sbo": "SBO:0000247", "kegg.compound": "C03344"}}, {"charge": 0, "name": "5alpha-Dihydrotestosterone", "formula": "C19H30O2", "compartment": "e", "id": "5adtststerone_e", "annotation": {"bigg.metabolite": "5adtststerone", "sbo": "SBO:0000247", "kegg.compound": "C03917"}}, {"charge": 0, "name": "Lysophosphatidylcholine", "formula": "C26.5654H50.5778N1.0O7.0P1.0", "compartment": "e", "id": "lpchol_e", "annotation": {"bigg.metabolite": "lpchol_hs", "sbo": "SBO:0000247", "kegg.compound": "C04230"}}, {"charge": 0, "name": "Phosphatidylethanolamine (bacteria)", "formula": "C38.171H74.2872N1.0O8.0P1.0", "compartment": "m", "id": "pe_BAC_m", "annotation": {"bigg.metabolite": ["pe181", "pe180", "pe161", "pe160", "pe141", "pe140", "pe120", "pe_SA", "pe_hs", "pe_EC", "pe_HP", "pe_SC"], "sbo": "SBO:0000247"}}, {"charge": 0, "name": "1-Acyl-sn-glycero-3-phosphoethanolamine;2-Acyl-sn-glycero-3-phosphoethanolamine", "formula": "C23.5654H44.5778N1.0O7.0P1.0", "compartment": "c", "id": "acg3pe_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C04438"}}, {"charge": -2, "name": "Quinolinate", "formula": "C7H3NO4", "compartment": "m", "id": "quln_m", "annotation": {"bigg.metabolite": "quln", "sbo": "SBO:0000247", "kegg.compound": "C03722"}}, {"charge": -5, "name": "3-Methylglutaconyl-CoA", "formula": "C27H37N7O19P3S", "compartment": "m", "id": "3mgcoa_m", "annotation": {"bigg.metabolite": "3mgcoa", "sbo": "SBO:0000247", "kegg.compound": "C03231"}}, {"charge": -5, "name": "Glutaryl-CoA", "formula": "C26H37N7O19P3S", "compartment": "m", "id": "glutcoa_m", "annotation": {"bigg.metabolite": "glutcoa", "sbo": "SBO:0000247", "kegg.compound": "C00527"}}, {"charge": -1, "name": "Thiocyanate", "formula": "CNS", "compartment": "e", "id": "tcynt_e", "annotation": {"bigg.metabolite": "tcynt", "sbo": "SBO:0000247", "kegg.compound": "C01755"}}, {"charge": -1, "name": "Phosphatidylinositol", "formula": "C46.1308H79.1556O13.0P1.0", "compartment": "e", "id": "pail_e", "annotation": {"bigg.metabolite": "pail_hs", "sbo": "SBO:0000247", "kegg.compound": "C01194"}}, {"charge": -1, "name": "L-Arginine phosphate", "formula": "C6H14N4O5P", "compartment": "c", "id": "argp_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C05945"}}, {"charge": -1, "name": "L-erythro-4-Hydroxyglutamate", "formula": "C5H8NO5", "compartment": "c", "id": "e4hglu_c", "annotation": {"bigg.metabolite": "e4hglu", "sbo": "SBO:0000247", "kegg.compound": "C05947"}}, {"charge": -2, "name": "4-Hydroxy-2-oxoglutarate", "formula": "C5H4O6", "compartment": "c", "id": "4h2oglt_c", "annotation": {"bigg.metabolite": "4h2oglt", "sbo": "SBO:0000247", "kegg.compound": "C05946"}}, {"charge": 0, "name": "D-3-Amino-isobutanoate", "formula": "C4H9NO2", "compartment": "c", "id": "3aib-D_c", "annotation": {"bigg.metabolite": "3aib-D", "sbo": "SBO:0000247", "kegg.compound": "C01205"}}, {"charge": -4, "name": "trans-Dodec-2-enoyl-CoA", "formula": "C33H52N7O17P3S", "compartment": "c", "id": "dd2coa_c", "annotation": {"bigg.metabolite": "dd2coa", "sbo": "SBO:0000247", "kegg.compound": "C03221"}}, {"charge": 0, "name": "3-Hydroxy-L-kynurenine", "formula": "C10H12N2O4", "compartment": "c", "id": "hLkynr_c", "annotation": {"bigg.metabolite": "hLkynr", "sbo": "SBO:0000247", "kegg.compound": "C03227"}}, {"charge": 0, "name": "Indole-3-acetaldehyde", "formula": "C10H9NO", "compartment": "m", "id": "id3acald_m", "annotation": {"bigg.metabolite": "id3acald", "sbo": "SBO:0000247", "kegg.compound": "C00637"}}, {"charge": -4, "name": "Isobutyryl-CoA", "formula": "C25H38N7O17P3S", "compartment": "m", "id": "ibcoa_m", "annotation": {"bigg.metabolite": "ibcoa", "sbo": "SBO:0000247", "kegg.compound": "C00630"}}, {"charge": 4, "name": "Spermine", "formula": "C10H30N4", "compartment": "e", "id": "sprm_e", "annotation": {"bigg.metabolite": "sprm", "sbo": "SBO:0000247", "kegg.compound": "C00750"}}, {"charge": -1, "name": "N-Carbamoyl-beta-alanine", "formula": "C4H7N2O3", "compartment": "c", "id": "cala_c", "annotation": {"bigg.metabolite": "cala", "sbo": "SBO:0000247", "kegg.compound": "C02642"}}, {"charge": 0, "name": "Lysophosphatidylcholine", "formula": "C26.5654H50.5778N1.0O7.0P1.0", "compartment": "c", "id": "lpchol_c", "annotation": {"bigg.metabolite": "lpchol_hs", "sbo": "SBO:0000247", "kegg.compound": "C04230"}}, {"charge": 0, "name": "Glycerol", "formula": "C3H8O3", "compartment": "e", "id": "glyc_e", "annotation": {"bigg.metabolite": "glyc", "sbo": "SBO:0000247", "kegg.compound": "C00116"}}, {"charge": -1, "name": "4-Imidazolone-5-propanoate", "formula": "C6H7N2O3", "compartment": "c", "id": "4izp_c", "annotation": {"bigg.metabolite": "4izp", "sbo": "SBO:0000247", "kegg.compound": "C03680"}}, {"charge": 0, "name": "\"6-Pyruvoyl-5,6,7,8-tetrahydropterin\"", "formula": "C9H11N5O3", "compartment": "c", "id": "6pthp_c", "annotation": {"bigg.metabolite": "6pthp", "sbo": "SBO:0000247", "kegg.compound": "C03684"}}, {"charge": -2, "name": "D-Glucarate", "formula": "C6H8O8", "compartment": "c", "id": "glcr_c", "annotation": {"bigg.metabolite": "glcr", "sbo": "SBO:0000247", "kegg.compound": "C00818"}}, {"charge": 0, "name": "L-2-Amino-3-oxobutanoate", "formula": "C4H7NO3", "compartment": "m", "id": "2aobut_m", "annotation": {"bigg.metabolite": "2aobut", "sbo": "SBO:0000247", "kegg.compound": "C03508"}}, {"charge": -1, "name": "trans-4-Hydroxycinnamate", "formula": "C9H7O3", "compartment": "c", "id": "T4hcinnm_c", "annotation": {"bigg.metabolite": "T4hcinnm", "sbo": "SBO:0000247", "kegg.compound": "C00811"}}, {"charge": -1, "name": "Cob(I)alamin", "formula": "C62H88CoN13O14P", "compartment": "m", "id": "cbl1_m", "annotation": {"bigg.metabolite": "cbl1", "sbo": "SBO:0000247", "kegg.compound": "C00853"}}, {"charge": 2, "name": "S-Adenosylmethioninamine", "formula": "C14H24N6O3S", "compartment": "e", "id": "ametam_e", "annotation": {"bigg.metabolite": "ametam", "sbo": "SBO:0000247", "kegg.compound": "C01137"}}, {"charge": -1, "name": "Propionate (n-C3:0)", "formula": "C3H5O2", "compartment": "m", "id": "ppa_m", "annotation": {"bigg.metabolite": "ppa", "sbo": "SBO:0000247", "kegg.compound": "C00163"}}, {"charge": -2, "name": "Bilirubin beta-diglucuronide", "formula": "C45H50N4O18", "compartment": "c", "id": "bildglcur_c", "annotation": {"bigg.metabolite": "bildglcur", "sbo": "SBO:0000247", "kegg.compound": "C05787"}}, {"charge": 0, "name": "5alpha-Dihydrotestosterone", "formula": "C19H30O2", "compartment": "c", "id": "5adtststerone_c", "annotation": {"bigg.metabolite": "5adtststerone", "sbo": "SBO:0000247", "kegg.compound": "C03917"}}, {"charge": 1, "name": "Histone N6,N6-dimethyl-L-lysine", "formula": "XC8H17N2O", "compartment": "c", "id": "Ndmelys_c", "annotation": {"bigg.metabolite": "Ndmelys", "sbo": "SBO:0000247", "kegg.compound": "C05545"}}, {"charge": 1, "name": "Protein N6,N6,N6-trimethyl-L-lysine", "formula": "XC9H19N2O", "compartment": "c", "id": "peptmelys_c", "annotation": {"bigg.metabolite": "Ntmelys", "sbo": "SBO:0000247", "kegg.compound": "C05546"}}, {"charge": -1, "name": "Nicotinate", "formula": "C6H4NO2", "compartment": "c", "id": "nac_c", "annotation": {"bigg.metabolite": "nac", "sbo": "SBO:0000247", "kegg.compound": "C00253"}}, {"charge": 0, "name": "Pyridoxal", "formula": "C8H9NO3", "compartment": "c", "id": "pydx_c", "annotation": {"bigg.metabolite": "pydx", "sbo": "SBO:0000247", "kegg.compound": "C00250"}}, {"charge": -1, "name": "D-Lactate", "formula": "C3H5O3", "compartment": "c", "id": "lac-D_c", "annotation": {"bigg.metabolite": "lac-D", "sbo": "SBO:0000247", "kegg.compound": "C00256"}}, {"charge": -1, "name": "D-Gluconate", "formula": "C6H11O7", "compartment": "c", "id": "glcn_c", "annotation": {"bigg.metabolite": "glcn", "sbo": "SBO:0000247", "kegg.compound": "C00257"}}, {"charge": 0, "name": "Riboflavin", "formula": "C17H20N4O6", "compartment": "c", "id": "ribflv_c", "annotation": {"bigg.metabolite": "ribflv", "sbo": "SBO:0000247", "kegg.compound": "C00255"}}, {"charge": -1, "name": "(R)-Glycerate", "formula": "C3H5O4", "compartment": "c", "id": "glyc-R_c", "annotation": {"bigg.metabolite": "glyc-R", "sbo": "SBO:0000247", "kegg.compound": "C00258"}}, {"charge": 0, "name": "L-Arabinose", "formula": "C5H10O5", "compartment": "c", "id": "arab-L_c", "annotation": {"bigg.metabolite": "arab-L", "sbo": "SBO:0000247", "kegg.compound": "C00259"}}, {"charge": 0, "name": "Hydrogen sulfide", "formula": "H2S", "compartment": "m", "id": "h2s_m", "annotation": {"bigg.metabolite": "h2s", "sbo": "SBO:0000247", "kegg.compound": "C00283"}}, {"charge": 0, "name": "Raffinose", "formula": "C18H32O16", "compartment": "c", "id": "raffin_c", "annotation": {"bigg.metabolite": "raffin", "sbo": "SBO:0000247", "kegg.compound": "C00492"}}, {"charge": 0, "name": "L-Tryptophan", "formula": "C11H12N2O2", "compartment": "c", "id": "trp-L_c", "annotation": {"bigg.metabolite": "trp-L", "sbo": "SBO:0000247", "kegg.compound": "C00078"}}, {"charge": 0, "name": "L-Phenylalanine", "formula": "C9H11NO2", "compartment": "c", "id": "phe-L_c", "annotation": {"bigg.metabolite": "phe-L", "sbo": "SBO:0000247", "kegg.compound": "C00079"}}, {"charge": -1, "name": "Ascaroside 5", "formula": "C9H15O6", "compartment": "e", "id": "ascr5_e", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -1, "name": "Ascaroside 3", "formula": "C15H25O6", "compartment": "e", "id": "ascr3_e", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -1, "name": "Ascaroside 1", "formula": "C13H23O6", "compartment": "e", "id": "ascr1_e", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -1, "name": "Ascaroside 10", "formula": "C15H27O6", "compartment": "e", "id": "ascr10_e", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 0, "name": "L-Ascorbate", "formula": "C6H8O6", "compartment": "c", "id": "ascb-L_c", "annotation": {"bigg.metabolite": "ascb-L", "sbo": "SBO:0000247", "kegg.compound": "C00072"}}, {"charge": 0, "name": "L-Methionine", "formula": "C5H11NO2S", "compartment": "c", "id": "met-L_c", "annotation": {"bigg.metabolite": "met-L", "sbo": "SBO:0000247", "kegg.compound": "C00073"}}, {"charge": 0, "name": "Fatty aldehyde", "formula": "C18.0H36.0O1.0", "compartment": "c", "id": "fattyald_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C00071"}}, {"charge": 1, "name": "Ornithine", "formula": "C5H13N2O2", "compartment": "c", "id": "orn_c", "annotation": {"bigg.metabolite": "orn", "sbo": "SBO:0000247", "kegg.compound": "C00077"}}, {"charge": -3, "name": "Phosphoenolpyruvate", "formula": "C3H2O6P", "compartment": "c", "id": "pep_c", "annotation": {"bigg.metabolite": "pep", "sbo": "SBO:0000247", "kegg.compound": "C00074"}}, {"charge": -4, "name": "UTP", "formula": "C9H11N2O15P3", "compartment": "c", "id": "utp_c", "annotation": {"bigg.metabolite": "utp", "sbo": "SBO:0000247", "kegg.compound": "C00075"}}, {"charge": -1, "name": "Pyruvate", "formula": "C3H3O3", "compartment": "e", "id": "pyr_e", "annotation": {"bigg.metabolite": "pyr", "sbo": "SBO:0000247", "kegg.compound": "C00022"}}, {"charge": 0, "name": "S-Adenosyl-L-homocysteine", "formula": "C14H20N6O5S", "compartment": "e", "id": "ahcys_e", "annotation": {"bigg.metabolite": "ahcys", "sbo": "SBO:0000247", "kegg.compound": "C00021"}}, {"charge": -2, "name": "AMP", "formula": "C10H12N5O7P", "compartment": "e", "id": "amp_e", "annotation": {"bigg.metabolite": "amp", "sbo": "SBO:0000247", "kegg.compound": "C00020"}}, {"charge": 0, "name": "Hydrogen peroxide", "formula": "H2O2", "compartment": "e", "id": "h2o2_e", "annotation": {"bigg.metabolite": "h2o2", "sbo": "SBO:0000247", "kegg.compound": "C00027"}}, {"charge": -2, "name": "2-Oxoglutarate", "formula": "C5H4O5", "compartment": "e", "id": "akg_e", "annotation": {"bigg.metabolite": "akg", "sbo": "SBO:0000247", "kegg.compound": "C00026"}}, {"charge": -1, "name": "L-Glutamate", "formula": "C5H8NO4", "compartment": "e", "id": "glu-L_e", "annotation": {"bigg.metabolite": "glu-L", "sbo": "SBO:0000247", "kegg.compound": "C00025"}}, {"charge": 1, "name": "Peptidyl-L-lysine", "formula": "XC6H13N2O", "compartment": "e", "id": "peplys_e", "annotation": {"bigg.metabolite": "peplys", "sbo": "SBO:0000247", "kegg.compound": "C02188"}}, {"charge": 0, "name": "sn-Glycero-3-phosphocholine", "formula": "C8H20NO6P", "compartment": "c", "id": "g3pc_c", "annotation": {"bigg.metabolite": "g3pc", "sbo": "SBO:0000247", "kegg.compound": "C00670"}}, {"charge": -1, "name": "(S)-3-Methyl-2-oxopentanoate", "formula": "C6H9O3", "compartment": "c", "id": "3mop_c", "annotation": {"bigg.metabolite": "3mop", "sbo": "SBO:0000247", "kegg.compound": "C00671"}}, {"charge": -2, "name": "2-Deoxy-D-ribose 1-phosphate", "formula": "C5H9O7P", "compartment": "c", "id": "2dr1p_c", "annotation": {"bigg.metabolite": "2dr1p", "sbo": "SBO:0000247", "kegg.compound": "C00672"}}, {"charge": -2, "name": "2-Deoxy-D-ribose 5-phosphate", "formula": "C5H9O7P", "compartment": "c", "id": "2dr5p_c", "annotation": {"bigg.metabolite": "2dr5p", "sbo": "SBO:0000247", "kegg.compound": "C00673"}}, {"charge": -1, "name": "L-Aspartate", "formula": "C4H6NO4", "compartment": "m", "id": "asp-L_m", "annotation": {"bigg.metabolite": "asp-L", "sbo": "SBO:0000247", "kegg.compound": "C00049"}}, {"charge": 1, "name": "Acetylcholine", "formula": "C7H16NO2", "compartment": "e", "id": "ach_e", "annotation": {"bigg.metabolite": "ach", "sbo": "SBO:0000247", "kegg.compound": "C01996"}}, {"charge": 0, "name": "L-Isoleucine", "formula": "C6H13NO2", "compartment": "e", "id": "ile-L_e", "annotation": {"bigg.metabolite": "ile-L", "sbo": "SBO:0000247", "kegg.compound": "C00407"}}, {"charge": -1, "name": "3-Methyl-2-oxobutanoate", "formula": "C5H7O3", "compartment": "e", "id": "3mob_e", "annotation": {"bigg.metabolite": "3mob", "sbo": "SBO:0000247", "kegg.compound": "C00141"}}, {"charge": 0, "name": "Uracil", "formula": "C4H4N2O2", "compartment": "c", "id": "ura_c", "annotation": {"bigg.metabolite": "ura", "sbo": "SBO:0000247", "kegg.compound": "C00106"}}, {"charge": -3, "name": "IDP", "formula": "C10H11N4O11P2", "compartment": "c", "id": "idp_c", "annotation": {"bigg.metabolite": "idp", "sbo": "SBO:0000247", "kegg.compound": "C00104"}}, {"charge": -2, "name": "UMP", "formula": "C9H11N2O9P", "compartment": "c", "id": "ump_c", "annotation": {"bigg.metabolite": "ump", "sbo": "SBO:0000247", "kegg.compound": "C00105"}}, {"charge": -2, "name": "D-Glucose 1-phosphate", "formula": "C6H11O9P", "compartment": "c", "id": "g1p_c", "annotation": {"bigg.metabolite": "g1p", "sbo": "SBO:0000247", "kegg.compound": "C00103"}}, {"charge": -4, "name": "Propanoyl-CoA", "formula": "C24H36N7O17P3S", "compartment": "c", "id": "ppcoa_c", "annotation": {"bigg.metabolite": "ppcoa", "sbo": "SBO:0000247", "kegg.compound": "C00100"}}, {"charge": -2, "name": "\"5,6,7,8-Tetrahydrofolate\"", "formula": "C19H21N7O6", "compartment": "c", "id": "thf_c", "annotation": {"bigg.metabolite": "thf", "sbo": "SBO:0000247", "kegg.compound": "C00101"}}, {"charge": 0, "name": "Hydrogen cyanide", "formula": "CHN", "compartment": "m", "id": "cyan_m", "annotation": {"bigg.metabolite": "cyan", "sbo": "SBO:0000247", "kegg.compound": "C01326"}}, {"charge": -1, "name": "Anthranilate", "formula": "C7H6NO2", "compartment": "c", "id": "anth_c", "annotation": {"bigg.metabolite": "anth", "sbo": "SBO:0000247", "kegg.compound": "C00108"}}, {"charge": -1, "name": "2-Oxobutanoate", "formula": "C4H5O3", "compartment": "c", "id": "2obut_c", "annotation": {"bigg.metabolite": "2obut", "sbo": "SBO:0000247", "kegg.compound": "C00109"}}, {"charge": 0, "name": "taurocholic acid", "formula": "C26H45NO7S", "compartment": "e", "id": "tchola_e", "annotation": {"bigg.metabolite": "tchola", "sbo": "SBO:0000247", "kegg.compound": "C05122"}}, {"charge": 0, "name": "L-Proline", "formula": "C5H9NO2", "compartment": "e", "id": "pro-L_e", "annotation": {"bigg.metabolite": "pro-L", "sbo": "SBO:0000247", "kegg.compound": "C00148"}}, {"charge": 1, "name": "Choline", "formula": "C5H14NO", "compartment": "e", "id": "chol_e", "annotation": {"bigg.metabolite": "chol", "sbo": "SBO:0000247", "kegg.compound": "C00114"}}, {"charge": -4, "name": "Tetradecanoyl-CoA (n-C14:0CoA)", "formula": "C35H58N7O17P3S", "compartment": "m", "id": "tdcoa_m", "annotation": {"bigg.metabolite": "tdcoa", "sbo": "SBO:0000247", "kegg.compound": "C02593"}}, {"charge": -5, "name": "(R)-Methylmalonyl-CoA", "formula": "C25H35N7O19P3S", "compartment": "m", "id": "mmcoa-R_m", "annotation": {"bigg.metabolite": "mmcoa-R", "sbo": "SBO:0000247", "kegg.compound": "C01213"}}, {"charge": -1, "name": "Succinic semialdehyde", "formula": "C4H5O3", "compartment": "e", "id": "sucsal_e", "annotation": {"bigg.metabolite": "sucsal", "sbo": "SBO:0000247", "kegg.compound": "C00232"}}, {"charge": -1, "name": "4-Methyl-2-oxopentanoate", "formula": "C6H9O3", "compartment": "e", "id": "4mop_e", "annotation": {"bigg.metabolite": "4mop", "sbo": "SBO:0000247", "kegg.compound": "C00233"}}, {"charge": 0, "name": "Procollagen L-proline (to be modified)", "formula": "XH", "compartment": "c", "id": "pcollgpro_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C01078"}}, {"charge": 0, "name": "S-Farnesyl protein", "formula": "C20H33N2O3SR(C2H2NOR)n(C2H2NOR)n", "compartment": "c", "id": "protSfar_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C20120"}}, {"charge": -2, "name": "dCMP", "formula": "C9H12N3O7P", "compartment": "e", "id": "dcmp_e", "annotation": {"bigg.metabolite": "dcmp", "sbo": "SBO:0000247", "kegg.compound": "C00239"}}, {"charge": -4, "name": "(S)-2-[5-Amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido]succinate", "formula": "C13H15N4O12P", "compartment": "c", "id": "25aics_c", "annotation": {"bigg.metabolite": "25aics", "sbo": "SBO:0000247", "kegg.compound": "C04823"}}, {"charge": 0, "name": "L-Valine", "formula": "C5H11NO2", "compartment": "m", "id": "val-L_m", "annotation": {"bigg.metabolite": "val-L", "sbo": "SBO:0000247", "kegg.compound": "C00183"}}, {"charge": -1, "name": "L-Lactate", "formula": "C3H5O3", "compartment": "m", "id": "lac-L_m", "annotation": {"bigg.metabolite": "lac-L", "sbo": "SBO:0000247", "kegg.compound": "C00186"}}, {"charge": 0, "name": "Cholesterol", "formula": "C27H46O", "compartment": "m", "id": "chsterol_m", "annotation": {"bigg.metabolite": "chsterol", "sbo": "SBO:0000247", "kegg.compound": "C00187"}}, {"charge": 0, "name": "L-Threonine", "formula": "C4H9NO3", "compartment": "m", "id": "thr-L_m", "annotation": {"bigg.metabolite": "thr-L", "sbo": "SBO:0000247", "kegg.compound": "C00188"}}, {"charge": 1, "name": "Octopamine", "formula": "C8H12NO2", "compartment": "e", "id": "octpmn_e", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C04227"}}, {"charge": -2, "name": "Thiamine diphosphate", "formula": "C12H16N4O7P2S", "compartment": "e", "id": "thmpp_e", "annotation": {"bigg.metabolite": "thmpp", "sbo": "SBO:0000247", "kegg.compound": "C00068"}}, {"charge": -2, "name": "\"2,3-diketo-5-methylthio-1-phosphopentane\"", "formula": "C6H9O6PS", "compartment": "c", "id": "dkmpp_c", "annotation": {"bigg.metabolite": "dkmpp", "sbo": "SBO:0000247", "kegg.compound": "C15650"}}, {"charge": -1, "name": "retinoyl glucuronide", "formula": "C26H35O8", "compartment": "e", "id": "retnglc_e", "annotation": {"bigg.metabolite": "retnglc", "sbo": "SBO:0000247", "kegg.compound": "C11061"}}, {"charge": 1, "name": "Glycyl-tRNA(Gly)", "formula": "C2H5NO2R", "compartment": "c", "id": "glytrna_c", "annotation": {"bigg.metabolite": "glytrna", "sbo": "SBO:0000247", "kegg.compound": "C02412"}}, {"charge": -1, "name": "Choline phosphate", "formula": "C5H13NO4P", "compartment": "e", "id": "cholp_e", "annotation": {"bigg.metabolite": "cholp", "sbo": "SBO:0000247", "kegg.compound": "C00588"}}, {"charge": 1, "name": "Histone-L-Lysine", "formula": "XC6H13N2O", "compartment": "c", "id": "Nlys_c", "annotation": {"bigg.metabolite": "peplys", "sbo": "SBO:0000247", "kegg.compound": "C02415"}}, {"charge": -1, "name": "Prostaglandin E2", "formula": "C20H31O5", "compartment": "e", "id": "prostge2_e", "annotation": {"bigg.metabolite": "prostge2", "sbo": "SBO:0000247", "kegg.compound": "C00584"}}, {"charge": 0, "name": "Propylene glycol", "formula": "C3H8O2", "compartment": "e", "id": "12ppd-R_e", "annotation": {"bigg.metabolite": "12ppd-R", "sbo": "SBO:0000247", "kegg.compound": "C00583"}}, {"charge": -4, "name": "dCTP", "formula": "C9H12N3O13P3", "compartment": "m", "id": "dctp_m", "annotation": {"bigg.metabolite": "dctp", "sbo": "SBO:0000247", "kegg.compound": "C00458"}}, {"charge": -4, "name": "dTTP", "formula": "C10H13N2O14P3", "compartment": "m", "id": "dttp_m", "annotation": {"bigg.metabolite": "dttp", "sbo": "SBO:0000247", "kegg.compound": "C00459"}}, {"charge": -1, "name": "Ethanolamine phosphate", "formula": "C2H7NO4P", "compartment": "e", "id": "ethamp_e", "annotation": {"bigg.metabolite": "ethamp", "sbo": "SBO:0000247", "kegg.compound": "C00346"}}, {"charge": -1, "name": "phosphatidylglycerol ", "formula": "C43.1308H75.1556O10.0P1.0", "compartment": "e", "id": "pglyc_e", "annotation": {"bigg.metabolite": "pglyc_hs", "sbo": "SBO:0000247", "kegg.compound": "C00344"}}, {"charge": -1, "name": "NMN", "formula": "C11H14N2O8P", "compartment": "m", "id": "nmn_m", "annotation": {"bigg.metabolite": "nmn", "sbo": "SBO:0000247", "kegg.compound": "C00455"}}, {"charge": -4, "name": "R total 4 coenzyme A", "formula": "C38.3018H62.5094N7.0O17.0P3.0S1.0", "compartment": "c", "id": "Rtotal4coa_c", "annotation": {"bigg.metabolite": ["Rtotalcoa", "Rtotal2coa", "Rtotal3coa", "acoa"], "sbo": "SBO:0000247"}}, {"charge": -1, "name": "R total 5 position", "formula": "C17.3018H31.5094O2.0", "compartment": "c", "id": "Rtotal5_c", "annotation": {"bigg.metabolite": ["Rtotal", "Rtotal2", "Rtotal3"], "sbo": "SBO:0000247"}}, {"charge": -4, "name": "R total 5 coenzyme A", "formula": "C38.3018H62.5094N7.0O17.0P3.0S1.0", "compartment": "c", "id": "Rtotal5coa_c", "annotation": {"bigg.metabolite": ["Rtotalcoa", "Rtotal2coa", "Rtotal3coa", "acoa"], "sbo": "SBO:0000247"}}, {"charge": -1, "name": "R total 3 position", "formula": "C17.3018H31.5094O2.0", "compartment": "c", "id": "Rtotal3_c", "annotation": {"bigg.metabolite": ["Rtotal", "Rtotal2", "Rtotal3"], "sbo": "SBO:0000247"}}, {"charge": -2, "name": "Phosphatidic acid (TAG)", "formula": "C37.6036H68.0188O8.0P1.0", "compartment": "c", "id": "pa_tag_c", "annotation": {"bigg.metabolite": ["pa_hs", "pa_Hp"], "sbo": "SBO:0000247"}}, {"charge": -2, "name": "Lysophosphatidic acid (TAG)", "formula": "C20.3018H37.5094O7.0P1.0", "compartment": "c", "id": "alpa_tag_c", "annotation": {"bigg.metabolite": "alpa_hs", "sbo": "SBO:0000247"}}, {"charge": 0, "name": "diacylglycerol (TAG)", "formula": "C37.6036H69.0188O5.0", "compartment": "c", "id": "dag_tag_c", "annotation": {"bigg.metabolite": "dag_hs", "sbo": "SBO:0000247"}}, {"charge": -1, "name": "R total 4 position", "formula": "C17.3018H31.5094O2.0", "compartment": "c", "id": "Rtotal4_c", "annotation": {"bigg.metabolite": ["Rtotal", "Rtotal2", "Rtotal3"], "sbo": "SBO:0000247"}}, {"charge": 0, "name": "Octanoyl carnitine", "formula": "C15H29NO4", "compartment": "c", "id": "occrn_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -4, "name": "Intermediary fatty acid C14:2", "formula": "C35H54N7O17P3S", "compartment": "c", "id": "fa14p2n6coa_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 0, "name": "Galactitol", "formula": "C6H14O6", "compartment": "c", "id": "galt_c", "annotation": {"bigg.metabolite": "galt", "sbo": "SBO:0000247", "kegg.compound": "C01697"}}, {"charge": -4, "name": "Inorganic triphosphate", "formula": "HO10P3", "compartment": "m", "id": "pppi_m", "annotation": {"bigg.metabolite": "pppi", "sbo": "SBO:0000247", "kegg.compound": "C00536"}}, {"charge": -1, "name": "Chloride", "formula": "Cl", "compartment": "e", "id": "cl_e", "annotation": {"bigg.metabolite": "cl", "sbo": "SBO:0000247", "kegg.compound": "C00698"}}, {"charge": 0, "name": "4-Trimethylammoniobutanoate", "formula": "C7H15NO2", "compartment": "e", "id": "4tmeabutn_e", "annotation": {"bigg.metabolite": "4tmeabutn", "sbo": "SBO:0000247", "kegg.compound": "C01181"}}, {"charge": -2, "name": "Nicotinate D-ribonucleotide", "formula": "C11H12NO9P", "compartment": "e", "id": "nicrnt_e", "annotation": {"bigg.metabolite": "nicrnt", "sbo": "SBO:0000247", "kegg.compound": "C01185"}}, {"charge": -2, "name": "2-Acyl-1-alkyl-sn-glycero-3-phosphate", "formula": "C39.5654H73.5778O7.0P1.0", "compartment": "c", "id": "akac2gp_c", "annotation": {"bigg.metabolite": "ak2gp_hs", "sbo": "SBO:0000247", "kegg.compound": "C05977"}}, {"charge": -1, "name": "Cholate", "formula": "C24H39O5", "compartment": "e", "id": "cholate_e", "annotation": {"bigg.metabolite": "cholate", "sbo": "SBO:0000247", "kegg.compound": "C00695"}}, {"charge": -1, "name": "Prostaglandin D2", "formula": "C20H31O5", "compartment": "e", "id": "prostgd2_e", "annotation": {"bigg.metabolite": "prostgd2", "sbo": "SBO:0000247", "kegg.compound": "C00696"}}, {"charge": 1, "name": "Procollagen 5-hydroxy-L-lysine", "formula": "XHO", "compartment": "c", "id": "pcollg5hlys_c", "annotation": {"bigg.metabolite": "pcollg5hlys", "sbo": "SBO:0000247", "kegg.compound": "C01211"}}, {"charge": -1, "name": "N-Methylethanolamine phosphate", "formula": "C3H9NO4P", "compartment": "c", "id": "methamp_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C01210"}}, {"charge": -2, "name": "Xanthurenic acid", "formula": "C10H5NO4", "compartment": "e", "id": "xanate_e", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C02470"}}, {"charge": 0, "name": "D-Lactaldehyde", "formula": "C3H6O2", "compartment": "c", "id": "lald-D_c", "annotation": {"bigg.metabolite": "lald-D", "sbo": "SBO:0000247", "kegg.compound": "C05999"}}, {"charge": -3, "name": "3-Phosphohydroxypyruvate", "formula": "C3H2O7P", "compartment": "c", "id": "3php_c", "annotation": {"bigg.metabolite": "3php", "sbo": "SBO:0000247", "kegg.compound": "C03232"}}, {"charge": 1, "name": "trimethylamine", "formula": "C3H10N", "compartment": "e", "id": "tma_e", "annotation": {"bigg.metabolite": "tma", "sbo": "SBO:0000247", "kegg.compound": "C00565"}}, {"charge": -2, "name": "(S)-2-Hydroxyglutarate", "formula": "C5H6O5", "compartment": "c", "id": "2hglut_c", "annotation": {"bigg.metabolite": "S2hglut", "sbo": "SBO:0000247", "kegg.compound": "C02630"}}, {"charge": 1, "name": "Octopamine", "formula": "C8H12NO2", "compartment": "c", "id": "octpmn_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C04227"}}, {"charge": 0, "name": "2-Phenylacetamide", "formula": "C8H9NO", "compartment": "e", "id": "pad_e", "annotation": {"bigg.metabolite": "pad", "sbo": "SBO:0000247", "kegg.compound": "C02505"}}, {"charge": 0, "name": "Propionyl-carnitine", "formula": "C10H19NO4", "compartment": "m", "id": "pcrn_m", "annotation": {"bigg.metabolite": "pcrn", "sbo": "SBO:0000247"}}, {"charge": 0, "name": "Eumelanin", "formula": "C8H3NO3", "compartment": "c", "id": "eumelanin_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C17937"}}, {"charge": 1, "name": "L-Cysteinyl-tRNA(Cys)", "formula": "C3H7NO2SR", "compartment": "c", "id": "cystrna_c", "annotation": {"bigg.metabolite": "cystrna", "sbo": "SBO:0000247", "kegg.compound": "C03125"}}, {"charge": 1, "name": "L-Isoleucyl-tRNA(Ile)", "formula": "C6H13NO2R", "compartment": "c", "id": "iletrna_c", "annotation": {"bigg.metabolite": "iletrna", "sbo": "SBO:0000247", "kegg.compound": "C03127"}}, {"charge": 0, "name": "1-Alkyl-2-lyso-sn-glycero-3-phosphocholine", "formula": "C26.0H56.0N1.0O6.0P1.0", "compartment": "c", "id": "ak2lgchol_c", "annotation": {"bigg.metabolite": "ak2lgchol_hs", "sbo": "SBO:0000247", "kegg.compound": "C04317"}}, {"charge": -1, "name": "Leukotriene A4", "formula": "C20H29O3", "compartment": "e", "id": "leuktrA4_e", "annotation": {"bigg.metabolite": "leuktrA4", "sbo": "SBO:0000247", "kegg.compound": "C00909"}}, {"charge": 0, "name": "\"5,6-Dihydrothymine\"", "formula": "C5H8N2O2", "compartment": "e", "id": "56dthm_e", "annotation": {"bigg.metabolite": "56dthm", "sbo": "SBO:0000247", "kegg.compound": "C00906"}}, {"charge": -1, "name": "L-Gulonate", "formula": "C6H11O7", "compartment": "c", "id": "guln_c", "annotation": {"bigg.metabolite": "guln", "sbo": "SBO:0000247", "kegg.compound": "C00800"}}, {"charge": 0, "name": "Cys-Gly", "formula": "C5H10N2O3S", "compartment": "e", "id": "cgly_e", "annotation": {"bigg.metabolite": "cgly", "sbo": "SBO:0000247", "kegg.compound": "C01419"}}, {"charge": 0, "name": "Indole-5,6-quinone", "formula": "C8H5NO2", "compartment": "c", "id": "ind56qn_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C05579"}}, {"charge": -2, "name": "1D-myo-Inositol 3-phosphate", "formula": "C6H11O9P", "compartment": "c", "id": "mi3p-D_c", "annotation": {"bigg.metabolite": "mi3p-D", "sbo": "SBO:0000247", "kegg.compound": "C04006"}}, {"charge": 1, "name": "L-Asparaginyl-tRNA(Asn)", "formula": "C4H8N2O3R", "compartment": "m", "id": "asntrna_m", "annotation": {"bigg.metabolite": "asntrna", "sbo": "SBO:0000247", "kegg.compound": "C03402"}}, {"charge": 0, "name": "Guanine", "formula": "C5H5N5O", "compartment": "c", "id": "gua_c", "annotation": {"bigg.metabolite": "gua", "sbo": "SBO:0000247", "kegg.compound": "C00242"}}, {"charge": 0, "name": "Taurine", "formula": "C2H7NO3S", "compartment": "c", "id": "taur_c", "annotation": {"bigg.metabolite": "taur", "sbo": "SBO:0000247", "kegg.compound": "C00245"}}, {"charge": 0, "name": "Platelet-activating factor", "formula": "C28.0H58.0N1.0O7.0P1.0", "compartment": "e", "id": "paf_e", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C04598"}}, {"charge": -1, "name": "Hexadecanoate (n-C16:0)", "formula": "C16H31O2", "compartment": "c", "id": "hdca_c", "annotation": {"bigg.metabolite": "hdca", "sbo": "SBO:0000247", "kegg.compound": "C00249"}}, {"charge": 0, "name": "Testosterone", "formula": "C19H28O2", "compartment": "e", "id": "tststerone_e", "annotation": {"bigg.metabolite": "tststerone", "sbo": "SBO:0000247", "kegg.compound": "C00535"}}, {"charge": 0, "name": "L-Glutamyl-tRNA(Gln)", "formula": "C5H8NO4R", "compartment": "m", "id": "glutrna_gln_m", "annotation": {"bigg.metabolite": "glutrna(gln)", "sbo": "SBO:0000247", "kegg.compound": "C06112"}}, {"charge": 1, "name": "Tyramine", "formula": "C8H12NO", "compartment": "c", "id": "tym_c", "annotation": {"bigg.metabolite": "tym", "sbo": "SBO:0000247", "kegg.compound": "C00483"}}, {"charge": -2, "name": "L-sulfolactate", "formula": "C3H4O6S", "compartment": "c", "id": "sl-L_c", "annotation": {"bigg.metabolite": "sl-L", "sbo": "SBO:0000247", "kegg.compound": "C11499"}}, {"charge": -2, "name": "Bilirubin", "formula": "C33H34N4O6", "compartment": "c", "id": "bilirub_c", "annotation": {"bigg.metabolite": "bilirub", "sbo": "SBO:0000247", "kegg.compound": "C00486"}}, {"charge": -2, "name": "Thiamine diphosphate", "formula": "C12H16N4O7P2S", "compartment": "c", "id": "thmpp_c", "annotation": {"bigg.metabolite": "thmpp", "sbo": "SBO:0000247", "kegg.compound": "C00068"}}, {"charge": 0, "name": "Random peptide (special aminoacid carrier)", "formula": "X", "compartment": "e", "id": "pepX_e", "annotation": {"bigg.metabolite": "pepd", "sbo": "SBO:0000247"}}, {"charge": -2, "name": "Adenylylselenate", "formula": "C10H12N5O10PSe", "compartment": "c", "id": "adsel_c", "annotation": {"bigg.metabolite": "adsel", "sbo": "SBO:0000247", "kegg.compound": "C05686"}}, {"charge": -2, "name": "Selenite", "formula": "O3Se", "compartment": "c", "id": "selnt_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C05684"}}, {"charge": -2, "name": "FMN", "formula": "C17H19N4O9P", "compartment": "c", "id": "fmn_c", "annotation": {"bigg.metabolite": "fmn", "sbo": "SBO:0000247", "kegg.compound": "C00061"}}, {"charge": 0, "name": "Ascaroside 2", "formula": "C12H22O5", "compartment": "e", "id": "ascr2_e", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -4, "name": "CTP", "formula": "C9H12N3O14P3", "compartment": "c", "id": "ctp_c", "annotation": {"bigg.metabolite": "ctp", "sbo": "SBO:0000247", "kegg.compound": "C00063"}}, {"charge": 1, "name": "L-Arginine", "formula": "C6H15N4O2", "compartment": "c", "id": "arg-L_c", "annotation": {"bigg.metabolite": "arg-L", "sbo": "SBO:0000247", "kegg.compound": "C00062"}}, {"charge": 0, "name": "L-Serine", "formula": "C3H7NO3", "compartment": "c", "id": "ser-L_c", "annotation": {"bigg.metabolite": "ser-L", "sbo": "SBO:0000247", "kegg.compound": "C00065"}}, {"charge": 0, "name": "L-Glutamine", "formula": "C5H10N2O3", "compartment": "c", "id": "gln-L_c", "annotation": {"bigg.metabolite": "gln-L", "sbo": "SBO:0000247", "kegg.compound": "C00064"}}, {"charge": 0, "name": "Formaldehyde", "formula": "CH2O", "compartment": "c", "id": "fald_c", "annotation": {"bigg.metabolite": "fald", "sbo": "SBO:0000247", "kegg.compound": "C00067"}}, {"charge": 0, "name": "L-Arabinitol", "formula": "C5H12O5", "compartment": "e", "id": "abt_e", "annotation": {"bigg.metabolite": "abt", "sbo": "SBO:0000247", "kegg.compound": "C00532"}}, {"charge": -1, "name": "gamma-L-Glutamyl-L-cysteine", "formula": "C8H13N2O5S", "compartment": "c", "id": "glucys_c", "annotation": {"bigg.metabolite": "glucys", "sbo": "SBO:0000247", "kegg.compound": "C00669"}}, {"charge": -2, "name": "alpha-D-Glucose 6-phosphate", "formula": "C6H11O9P", "compartment": "c", "id": "g6p-A_c", "annotation": {"bigg.metabolite": "g6p", "sbo": "SBO:0000247", "kegg.compound": "C00668"}}, {"charge": -4, "name": "\"D-Fructose 2,6-bisphosphate\"", "formula": "C6H10O12P2", "compartment": "c", "id": "f26bp_c", "annotation": {"bigg.metabolite": "f26bp", "sbo": "SBO:0000247", "kegg.compound": "C00665"}}, {"charge": 1, "name": "Choline", "formula": "C5H14NO", "compartment": "c", "id": "chol_c", "annotation": {"bigg.metabolite": "chol", "sbo": "SBO:0000247", "kegg.compound": "C00114"}}, {"charge": -2, "name": "alpha-D-Ribose 5-phosphate", "formula": "C5H9O8P", "compartment": "c", "id": "r5p_c", "annotation": {"bigg.metabolite": "r5p", "sbo": "SBO:0000247", "kegg.compound": "C00117"}}, {"charge": 0, "name": "Glycerol", "formula": "C3H8O3", "compartment": "c", "id": "glyc_c", "annotation": {"bigg.metabolite": "glyc", "sbo": "SBO:0000247", "kegg.compound": "C00116"}}, {"charge": -2, "name": "Dihydroxyacetone phosphate", "formula": "C3H5O6P", "compartment": "c", "id": "dhap_c", "annotation": {"bigg.metabolite": "dhap", "sbo": "SBO:0000247", "kegg.compound": "C00111"}}, {"charge": -2, "name": "Dolichol phosphate", "formula": "C110H179O4P", "compartment": "c", "id": "dolp_c", "annotation": {"bigg.metabolite": "dolp", "sbo": "SBO:0000247", "kegg.compound": "C00110"}}, {"charge": -3, "name": "CDP", "formula": "C9H12N3O11P2", "compartment": "c", "id": "cdp_c", "annotation": {"bigg.metabolite": "cdp", "sbo": "SBO:0000247", "kegg.compound": "C00112"}}, {"charge": -5, "name": "5-Phospho-alpha-D-ribose 1-diphosphate", "formula": "C5H8O14P3", "compartment": "c", "id": "prpp_c", "annotation": {"bigg.metabolite": "prpp", "sbo": "SBO:0000247", "kegg.compound": "C00119"}}, {"charge": 0, "name": "Lactose", "formula": "C12H22O11", "compartment": "c", "id": "lcts_c", "annotation": {"bigg.metabolite": "lcts", "sbo": "SBO:0000247", "kegg.compound": "C00243"}}, {"charge": 1, "name": "Pyridoxamine", "formula": "C8H13N2O2", "compartment": "e", "id": "pydam_e", "annotation": {"bigg.metabolite": "pydam", "sbo": "SBO:0000247", "kegg.compound": "C00534"}}, {"charge": -1, "name": "R total", "formula": "C18.5654H31.5778O2.0", "compartment": "e", "id": "Rtotal_e", "annotation": {"bigg.metabolite": "Rtotal", "sbo": "SBO:0000247", "kegg.compound": "C00162"}}, {"charge": -1, "name": "Propionate (n-C3:0)", "formula": "C3H5O2", "compartment": "e", "id": "ppa_e", "annotation": {"bigg.metabolite": "ppa", "sbo": "SBO:0000247", "kegg.compound": "C00163"}}, {"charge": -1, "name": "Glycolate", "formula": "C2H3O3", "compartment": "e", "id": "glyclt_e", "annotation": {"bigg.metabolite": "glyclt", "sbo": "SBO:0000247", "kegg.compound": "C00160"}}, {"charge": -1, "name": "Phenylpyruvate", "formula": "C9H7O3", "compartment": "e", "id": "phpyr_e", "annotation": {"bigg.metabolite": "phpyr", "sbo": "SBO:0000247", "kegg.compound": "C00166"}}, {"charge": -3, "name": "UDP-D-glucuronate", "formula": "C15H19N2O18P2", "compartment": "e", "id": "udpglcur_e", "annotation": {"bigg.metabolite": "udpglcur", "sbo": "SBO:0000247", "kegg.compound": "C00167"}}, {"charge": -1, "name": "Acetoacetate", "formula": "C4H5O3", "compartment": "e", "id": "acac_e", "annotation": {"bigg.metabolite": "acac", "sbo": "SBO:0000247", "kegg.compound": "C00164"}}, {"charge": 0, "name": "27-Hydroxycholesterol", "formula": "C27H46O2", "compartment": "e", "id": "xol27oh_e", "annotation": {"bigg.metabolite": "xol27oh", "sbo": "SBO:0000247", "kegg.compound": "C15610"}}, {"charge": 0, "name": "N-Formyl-L-glutamate", "formula": "C6H9NO5", "compartment": "c", "id": "Nforglu_c", "annotation": {"bigg.metabolite": "Nforglu", "sbo": "SBO:0000247", "kegg.compound": "C01045"}}, {"charge": 0, "name": "Adenosylcobalamin", "formula": "C72H100CoN18O17P", "compartment": "m", "id": "adocbl_m", "annotation": {"bigg.metabolite": "adocbl", "sbo": "SBO:0000247", "kegg.compound": "C00194"}}, {"charge": 1, "name": "Histone-L-Lysine", "formula": "XC6H13N2O", "compartment": "e", "id": "Nlys_e", "annotation": {"bigg.metabolite": "peplys", "sbo": "SBO:0000247", "kegg.compound": "C02415"}}, {"charge": -2, "name": "2-Acyl-1-(1-alkenyl)-sn-glycero-3-phosphate", "formula": "C39.5654H71.5778O7.0P1.0", "compartment": "c", "id": "alkenac2gp_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C15647"}}, {"charge": 1, "name": "L-Methionyl-tRNA (Met)", "formula": "C5H11NO2SR", "compartment": "m", "id": "mettrna_m", "annotation": {"bigg.metabolite": "mettrna", "sbo": "SBO:0000247", "kegg.compound": "C02430"}}, {"charge": 0, "name": "heme A", "formula": "C49H54FeN4O6", "compartment": "m", "id": "hemea_m", "annotation": {"bigg.metabolite": "hemeA_#1", "sbo": "SBO:0000247", "kegg.compound": "C15670"}}, {"charge": 0, "name": "heme O", "formula": "C49H56FeN4O5", "compartment": "m", "id": "hemeo_m", "annotation": {"bigg.metabolite": "hemeo", "sbo": "SBO:0000247", "kegg.compound": "C15672"}}, {"charge": -1, "name": "L-Saccharopine", "formula": "C11H19N2O6", "compartment": "m", "id": "saccrp-L_m", "annotation": {"bigg.metabolite": "saccrp-L", "sbo": "SBO:0000247", "kegg.compound": "C00449"}}, {"charge": -1, "name": "w-hydroxyl leukotriene B4", "formula": "C20H31O5", "compartment": "e", "id": "leuktrB4woh_e", "annotation": {"bigg.metabolite": "leuktrB4woh", "sbo": "SBO:0000247", "kegg.compound": "C04853"}}, {"charge": -1, "name": "L-1-Pyrroline-3-hydroxy-5-carboxylate", "formula": "C5H6NO3", "compartment": "m", "id": "1p3h5c_m", "annotation": {"bigg.metabolite": "1p3h5c", "sbo": "SBO:0000247", "kegg.compound": "C04281"}}, {"charge": 0, "name": "\"3,4-Dihydroxy-L-phenylalanine\"", "formula": "C9H11NO4", "compartment": "e", "id": "34dhphe_e", "annotation": {"bigg.metabolite": "34dhphe", "sbo": "SBO:0000247", "kegg.compound": "C00355"}}, {"charge": -4, "name": "\"D-Fructose 1,6-bisphosphate\"", "formula": "C6H10O12P2", "compartment": "e", "id": "fdp_e", "annotation": {"bigg.metabolite": "fdp", "sbo": "SBO:0000247", "kegg.compound": "C00354"}}, {"charge": -1, "name": "\"5,10-Methenyltetrahydrofolate\"", "formula": "C20H20N7O6", "compartment": "m", "id": "methf_m", "annotation": {"bigg.metabolite": "methf", "sbo": "SBO:0000247", "kegg.compound": "C00445"}}, {"charge": 0, "name": "Phosphatidylethanolamine", "formula": "C42.1308H75.1556N1.0O8.0P1.0", "compartment": "e", "id": "pe_e", "annotation": {"bigg.metabolite": ["pe181", "pe180", "pe161", "pe160", "pe141", "pe140", "pe120", "pe_SA", "pe_hs", "pe_EC", "pe_HP", "pe_SC"], "sbo": "SBO:0000247", "kegg.compound": "C00350"}}, {"charge": -1, "name": "D-Glucosamine 6-phosphate", "formula": "C6H13NO8P", "compartment": "e", "id": "gam6p_e", "annotation": {"bigg.metabolite": "gam6p", "sbo": "SBO:0000247", "kegg.compound": "C00352"}}, {"charge": 0, "name": "Fatty acyl C8:1 carnitine", "formula": "C15H27NO4", "compartment": "c", "id": "fa8p1n3crn_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -4, "name": "Intermediary fatty acid C16:4", "formula": "C37H54N7O17P3S", "compartment": "c", "id": "fa16p4n3coa_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -4, "name": "Intermediary fatty acid C8:1", "formula": "C29H44N7O17P3S", "compartment": "c", "id": "fa8p1n3coa_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -4, "name": "Intermediary fatty acid C16:3", "formula": "C37H56N7O17P3S", "compartment": "c", "id": "fa16p3n6coa_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -4, "name": "cis-3,4-methylenedecanoyl coa", "formula": "C32H50N7O17P3S", "compartment": "c", "id": "fa11c3coa_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -4, "name": "Fatty acyl (C9:iso) coa", "formula": "C30H48N7O17P3S", "compartment": "c", "id": "fa9p0isocoa_c", "annotation": {"bigg.metabolite": "acoa", "sbo": "SBO:0000247"}}, {"charge": -4, "name": "Fatty acyl (C17:iso) coa", "formula": "C38H64N7O17P3S", "compartment": "c", "id": "fa17p0isocoa_c", "annotation": {"bigg.metabolite": "acoa", "sbo": "SBO:0000247"}}, {"charge": -4, "name": "Fatty acyl (C15:iso) coa", "formula": "C36H60N7O17P3S", "compartment": "c", "id": "fa15p0isocoa_c", "annotation": {"bigg.metabolite": "acoa", "sbo": "SBO:0000247"}}, {"charge": 0, "name": "Electron transfer flavoprotein reduced", "formula": "RH2", "compartment": "m", "id": "etfrd_m", "annotation": {"bigg.metabolite": "etfrd", "sbo": "SBO:0000247", "kegg.compound": "C04570"}}, {"charge": -4, "name": "cis-11,12-methyleneoctadecanoyl coa", "formula": "C40H66N7O17P3S", "compartment": "c", "id": "fa19c11coa_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -4, "name": "cis-9,10-methylenehexadecanoyl coa", "formula": "C38H62N7O17P3S", "compartment": "c", "id": "fa17c9coa_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -1, "name": "Phosphatidylinositol", "formula": "C46.1308H79.1556O13.0P1.0", "compartment": "c", "id": "pail_c", "annotation": {"bigg.metabolite": "pail_hs", "sbo": "SBO:0000247", "kegg.compound": "C01194"}}, {"charge": -2, "name": "O-Acetyl-ADP-ribose", "formula": "C17H23N5O15P2", "compartment": "c", "id": "ac_adprib_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C20658"}}, {"charge": 0, "name": "Adenosylcobalamin", "formula": "C72H100CoN18O17P", "compartment": "e", "id": "adocbl_e", "annotation": {"bigg.metabolite": "adocbl", "sbo": "SBO:0000247", "kegg.compound": "C00194"}}, {"charge": -1, "name": "L-Cysteate", "formula": "C3H6NO5S", "compartment": "m", "id": "Lcyst_m", "annotation": {"bigg.metabolite": "Lcyst", "sbo": "SBO:0000247", "kegg.compound": "C00506"}}, {"charge": -4, "name": "C20:4-CoA", "formula": "C41H62N7O17P3S", "compartment": "c", "id": "arachdcoa_c", "annotation": {"bigg.metabolite": "arachdcoa", "sbo": "SBO:0000247", "kegg.compound": "C02249"}}, {"charge": 1, "name": "Acetylcholine", "formula": "C7H16NO2", "compartment": "c", "id": "ach_c", "annotation": {"bigg.metabolite": "ach", "sbo": "SBO:0000247", "kegg.compound": "C01996"}}, {"charge": -1, "name": "Ethanolamine phosphate", "formula": "C2H7NO4P", "compartment": "c", "id": "ethamp_c", "annotation": {"bigg.metabolite": "ethamp", "sbo": "SBO:0000247", "kegg.compound": "C00346"}}, {"charge": -2, "name": "GDP-4-dehydro-6-deoxy-D-mannose", "formula": "C16H21N5O15P2", "compartment": "c", "id": "gdpddman_c", "annotation": {"bigg.metabolite": "gdpddman", "sbo": "SBO:0000247", "kegg.compound": "C01222"}}, {"charge": -1, "name": "3-(4-Hydroxyphenyl)pyruvate", "formula": "C9H7O4", "compartment": "e", "id": "34hpp_e", "annotation": {"bigg.metabolite": "34hpp", "sbo": "SBO:0000247", "kegg.compound": "C01179"}}, {"charge": 0, "name": "1-alkyl 2-acylglycerol 3-phosphocholine", "formula": "C44.5654H86.5778N1.0O7.0P1.0", "compartment": "c", "id": "akac2gchol_c", "annotation": {"bigg.metabolite": "ak2gchol_hs", "sbo": "SBO:0000247", "kegg.compound": "C05212"}}, {"charge": -2, "name": "5-Methylthio-5-deoxy-D-ribulose 1-phosphate", "formula": "C6H11O7PS", "compartment": "c", "id": "5mdru1p_c", "annotation": {"bigg.metabolite": "5mdru1p", "sbo": "SBO:0000247", "kegg.compound": "C04582"}}, {"charge": 0, "name": "myo-Inositol", "formula": "C6H12O6", "compartment": "e", "id": "inost_e", "annotation": {"bigg.metabolite": "inost", "sbo": "SBO:0000247", "kegg.compound": "C00137"}}, {"charge": -2, "name": "Oxaloacetate", "formula": "C4H2O5", "compartment": "m", "id": "oaa_m", "annotation": {"bigg.metabolite": "oaa", "sbo": "SBO:0000247", "kegg.compound": "C00036"}}, {"charge": -1, "name": "2-Hydroxybutyrate", "formula": "C4H7O3", "compartment": "c", "id": "2hb_c", "annotation": {"bigg.metabolite": "2hb", "sbo": "SBO:0000247", "kegg.compound": "C05984"}}, {"charge": -7, "name": "phosphatidylinositol-3,4,5-trisphosphate ", "formula": "C46.1308H76.1556O22.0P4.0", "compartment": "c", "id": "pail345p_c", "annotation": {"bigg.metabolite": "pail345p_hs", "sbo": "SBO:0000247", "kegg.compound": "C05981"}}, {"charge": -2, "name": "Cardiolipin", "formula": "C83.2616H142.3112O17.0P2.0", "compartment": "c", "id": "clpn_c", "annotation": {"bigg.metabolite": ["clpn181", "clpn180", "clpn161", "clpn160190", "clpn160", "clpn141", "clpn140", "clpn120", "clpn_SA", "clpn_hs", "clpn_HP", "clpn_EC"], "sbo": "SBO:0000247", "kegg.compound": "C05980"}}, {"charge": 0, "name": "beta-Carotene", "formula": "C40H56", "compartment": "e", "id": "caro_e", "annotation": {"bigg.metabolite": "caro", "sbo": "SBO:0000247", "kegg.compound": "C02094"}}, {"charge": 0, "name": "7 alpha-Hydroxycholesterol", "formula": "C27H46O2", "compartment": "c", "id": "xol7a_c", "annotation": {"bigg.metabolite": "xol7a", "sbo": "SBO:0000247", "kegg.compound": "C03594"}}, {"charge": -4, "name": "dihomo-gamma-linolenyl coenzyme A", "formula": "C41H64N7O17P3S", "compartment": "c", "id": "dlnlcgcoa_c", "annotation": {"bigg.metabolite": "dlnlcgcoa", "sbo": "SBO:0000247", "kegg.compound": "C03595"}}, {"charge": -1, "name": "Retinoate", "formula": "C20H27O2", "compartment": "e", "id": "retn_e", "annotation": {"bigg.metabolite": "retn", "sbo": "SBO:0000247", "kegg.compound": "C00777"}}, {"charge": 1, "name": "Dopamine", "formula": "C8H12NO2", "compartment": "c", "id": "dopa_c", "annotation": {"bigg.metabolite": "dopa", "sbo": "SBO:0000247", "kegg.compound": "C03758"}}, {"charge": 0, "name": "1-alkyl 2-acylglycerol", "formula": "C39.5654H74.5778O4.0", "compartment": "c", "id": "akac2g_c", "annotation": {"bigg.metabolite": "ak2g_hs", "sbo": "SBO:0000247", "kegg.compound": "C03201"}}, {"charge": -1, "name": "octadecanoate (n-C18:0)", "formula": "C18H35O2", "compartment": "c", "id": "ocdca_c", "annotation": {"bigg.metabolite": "ocdca", "sbo": "SBO:0000247", "kegg.compound": "C01530"}}, {"charge": 0, "name": "D-Glyceraldehyde", "formula": "C3H6O3", "compartment": "e", "id": "glyald_e", "annotation": {"bigg.metabolite": "glyald", "sbo": "SBO:0000247", "kegg.compound": "C00577"}}, {"charge": 0, "name": "Trehalose", "formula": "C12H22O11", "compartment": "e", "id": "tre_e", "annotation": {"bigg.metabolite": "tre", "sbo": "SBO:0000247", "kegg.compound": "C01083"}}, {"charge": 0, "name": "Tetrahydrobiopterin", "formula": "C9H15N5O3", "compartment": "e", "id": "thbpt_e", "annotation": {"bigg.metabolite": "thbpt", "sbo": "SBO:0000247", "kegg.compound": "C00272"}}, {"charge": 0, "name": "\"7alpha,12alpha-Dihydroxycholest-4-en-3-one\"", "formula": "C27H44O3", "compartment": "e", "id": "xoldiolone_e", "annotation": {"bigg.metabolite": "xoldiolone", "sbo": "SBO:0000247", "kegg.compound": "C17339"}}, {"charge": -1, "name": "7alpha-Hydroxy-3-oxo-4-cholestenoate", "formula": "C27H41O4", "compartment": "e", "id": "7a3o4chlstnt_e", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C17337"}}, {"charge": -1, "name": "Beta cyanoalanine", "formula": "C4H5N2O2", "compartment": "e", "id": "cyanala_e", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C02512"}}, {"charge": -3, "name": "1-Phosphatidyl-1D-myo-inositol 5-phosphate ", "formula": "C46.1308H78.1556O16.0P2.0", "compartment": "c", "id": "pail5p_c", "annotation": {"bigg.metabolite": "pail5p_hs", "sbo": "SBO:0000247", "kegg.compound": "C11557"}}, {"charge": -5, "name": "1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate(5-)", "formula": "C46.1308H77.1556O19.0P3.0", "compartment": "c", "id": "pail35p_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C11556"}}, {"charge": -5, "name": "phosphatidylinositol-3,4-bisphosphate ", "formula": "C46.1308H77.1556O19.0P3.0", "compartment": "c", "id": "pail34p_c", "annotation": {"bigg.metabolite": "pail34p_hs", "sbo": "SBO:0000247", "kegg.compound": "C11554"}}, {"charge": -2, "name": "1-Acyl-glycerone 3-phosphate", "formula": "C21.5654H35.5778O7.0P1.0", "compartment": "c", "id": "adhap_c", "annotation": {"bigg.metabolite": "1agly3p_SC", "sbo": "SBO:0000247", "kegg.compound": "C03372"}}, {"charge": -2, "name": "5-amino-1-(5-phospho-D-ribosyl)imidazole", "formula": "C8H12N3O7P", "compartment": "c", "id": "air_c", "annotation": {"bigg.metabolite": "air", "sbo": "SBO:0000247", "kegg.compound": "C03373"}}, {"charge": -1, "name": "Fatty acid (C15:iso)", "formula": "C15H29O2", "compartment": "c", "id": "fa15p0iso_c", "annotation": {"bigg.metabolite": ["fa9", "fa6", "fa5", "fa4", "fa3", "fa20n", "fa19a", "fa12", "fa11", "fa10", "fa1"], "sbo": "SBO:0000247"}}, {"charge": -4, "name": "Crotonoyl-CoA", "formula": "C25H36N7O17P3S", "compartment": "m", "id": "b2coa_m", "annotation": {"bigg.metabolite": "b2coa", "sbo": "SBO:0000247", "kegg.compound": "C00877"}}, {"charge": -1, "name": "Choline phosphate", "formula": "C5H13NO4P", "compartment": "c", "id": "cholp_c", "annotation": {"bigg.metabolite": "cholp", "sbo": "SBO:0000247", "kegg.compound": "C00588"}}, {"charge": 0, "name": "Propylene glycol", "formula": "C3H8O2", "compartment": "c", "id": "12ppd-R_c", "annotation": {"bigg.metabolite": "12ppd-R", "sbo": "SBO:0000247", "kegg.compound": "C00583"}}, {"charge": -1, "name": "Prostaglandin E2", "formula": "C20H31O5", "compartment": "c", "id": "prostge2_c", "annotation": {"bigg.metabolite": "prostge2", "sbo": "SBO:0000247", "kegg.compound": "C00584"}}, {"charge": -2, "name": "D-Erythrose 4-phosphate", "formula": "C4H7O7P", "compartment": "c", "id": "e4p_c", "annotation": {"bigg.metabolite": "e4p", "sbo": "SBO:0000247", "kegg.compound": "C00279"}}, {"charge": -1, "name": "Leukotriene A4", "formula": "C20H29O3", "compartment": "c", "id": "leuktrA4_c", "annotation": {"bigg.metabolite": "leuktrA4", "sbo": "SBO:0000247", "kegg.compound": "C00909"}}, {"charge": 0, "name": "\"5,6-Dihydrothymine\"", "formula": "C5H8N2O2", "compartment": "c", "id": "56dthm_c", "annotation": {"bigg.metabolite": "56dthm", "sbo": "SBO:0000247", "kegg.compound": "C00906"}}, {"charge": -2, "name": "D-Mannose 6-phosphate", "formula": "C6H11O9P", "compartment": "c", "id": "man6p_c", "annotation": {"bigg.metabolite": "man6p", "sbo": "SBO:0000247", "kegg.compound": "C00275"}}, {"charge": 0, "name": "Tetrahydrobiopterin", "formula": "C9H15N5O3", "compartment": "c", "id": "thbpt_c", "annotation": {"bigg.metabolite": "thbpt", "sbo": "SBO:0000247", "kegg.compound": "C00272"}}, {"charge": 0, "name": "Cytidine", "formula": "C9H13N3O5", "compartment": "c", "id": "cytd_c", "annotation": {"bigg.metabolite": "cytd", "sbo": "SBO:0000247", "kegg.compound": "C00475"}}, {"charge": 0, "name": "Retinol", "formula": "C20H30O", "compartment": "c", "id": "retinol_c", "annotation": {"bigg.metabolite": "retinol", "sbo": "SBO:0000247", "kegg.compound": "C00473"}}, {"charge": 0, "name": "Inosine", "formula": "C10H12N4O5", "compartment": "c", "id": "ins_c", "annotation": {"bigg.metabolite": "ins", "sbo": "SBO:0000247", "kegg.compound": "C00294"}}, {"charge": -1, "name": "Orotate", "formula": "C5H3N2O4", "compartment": "c", "id": "orot_c", "annotation": {"bigg.metabolite": "orot", "sbo": "SBO:0000247", "kegg.compound": "C00295"}}, {"charge": -2, "name": "Selenate", "formula": "O4Se", "compartment": "c", "id": "sel_c", "annotation": {"bigg.metabolite": "sel", "sbo": "SBO:0000247", "kegg.compound": "C05697"}}, {"charge": -4, "name": "3'-Phosphoadenylylselenate", "formula": "C10H11N5O13P2Se", "compartment": "c", "id": "3padsel_c", "annotation": {"bigg.metabolite": "3padsel", "sbo": "SBO:0000247", "kegg.compound": "C05696"}}, {"charge": 0, "name": "phospholipid component of E. coli diet", "formula": "C40.2301H77.5825N0.7702O8.85P1.05", "compartment": "e", "id": "phospholipid_BAC_e", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -1, "name": "3-mercaptolactate-cysteine disulfide", "formula": "C6H10O5S2N", "compartment": "e", "id": "mercplaccys_e", "annotation": {"bigg.metabolite": "mercplaccys", "sbo": "SBO:0000247"}}, {"charge": 0, "name": "Uridine", "formula": "C9H12N2O6", "compartment": "c", "id": "uri_c", "annotation": {"bigg.metabolite": "uri", "sbo": "SBO:0000247", "kegg.compound": "C00299"}}, {"charge": -2, "name": "5-Amino-1-(5-Phospho-D-ribosyl)imidazole-4-carboxamide", "formula": "C9H13N4O8P", "compartment": "e", "id": "aicar_e", "annotation": {"bigg.metabolite": "aicar", "sbo": "SBO:0000247", "kegg.compound": "C04677"}}, {"charge": -4, "name": "2-Methylbutanoyl-CoA", "formula": "C26H40N7O17P3S", "compartment": "m", "id": "2mbcoa_m", "annotation": {"bigg.metabolite": "2mbcoa", "sbo": "SBO:0000247", "kegg.compound": "C15980"}}, {"charge": 0, "name": "D-Ribose", "formula": "C5H10O5", "compartment": "c", "id": "rib-D_c", "annotation": {"bigg.metabolite": "rib-D", "sbo": "SBO:0000247", "kegg.compound": "C00121"}}, {"charge": -2, "name": "Fumarate", "formula": "C4H2O4", "compartment": "c", "id": "fum_c", "annotation": {"bigg.metabolite": "fum", "sbo": "SBO:0000247", "kegg.compound": "C00122"}}, {"charge": 0, "name": "L-Leucine", "formula": "C6H13NO2", "compartment": "c", "id": "leu-L_c", "annotation": {"bigg.metabolite": "leu-L", "sbo": "SBO:0000247", "kegg.compound": "C00123"}}, {"charge": 0, "name": "D-Galactose", "formula": "C6H12O6", "compartment": "c", "id": "gal_c", "annotation": {"bigg.metabolite": "gal", "sbo": "SBO:0000247", "kegg.compound": "C00124"}}, {"charge": 0, "name": "Uridine", "formula": "C9H12N2O6", "compartment": "m", "id": "uri_m", "annotation": {"bigg.metabolite": "uri", "sbo": "SBO:0000247", "kegg.compound": "C00299"}}, {"charge": -2, "name": "Oxidized glutathione", "formula": "C20H30N6O12S2", "compartment": "c", "id": "gthox_c", "annotation": {"bigg.metabolite": "gthox", "sbo": "SBO:0000247", "kegg.compound": "C00127"}}, {"charge": 0, "name": "Inosine", "formula": "C10H12N4O5", "compartment": "m", "id": "ins_m", "annotation": {"bigg.metabolite": "ins", "sbo": "SBO:0000247", "kegg.compound": "C00294"}}, {"charge": -3, "name": "Isopentenyl diphosphate", "formula": "C5H9O7P2", "compartment": "c", "id": "ipdp_c", "annotation": {"bigg.metabolite": "ipdp", "sbo": "SBO:0000247", "kegg.compound": "C00129"}}, {"charge": -1, "name": "Formate", "formula": "CH1O2", "compartment": "m", "id": "for_m", "annotation": {"bigg.metabolite": "for", "sbo": "SBO:0000247", "kegg.compound": "C00058"}}, {"charge": -2, "name": "Sulfate", "formula": "O4S", "compartment": "m", "id": "so4_m", "annotation": {"bigg.metabolite": "so4", "sbo": "SBO:0000247", "kegg.compound": "C00059"}}, {"charge": -4, "name": "\"Adenosine 3',5'-bisphosphate\"", "formula": "C10H11N5O10P2", "compartment": "m", "id": "pap_m", "annotation": {"bigg.metabolite": "pap", "sbo": "SBO:0000247", "kegg.compound": "C00054"}}, {"charge": -2, "name": "CMP", "formula": "C9H12N3O8P", "compartment": "m", "id": "cmp_m", "annotation": {"bigg.metabolite": "cmp", "sbo": "SBO:0000247", "kegg.compound": "C00055"}}, {"charge": -2, "name": "3-Sulfopyruvate", "formula": "C3H2O6S", "compartment": "m", "id": "3spyr_m", "annotation": {"bigg.metabolite": "3spyr", "sbo": "SBO:0000247", "kegg.compound": "C05528"}}, {"charge": -1, "name": "Reduced glutathione", "formula": "C10H16N3O6S", "compartment": "m", "id": "gthrd_m", "annotation": {"bigg.metabolite": "gthrd", "sbo": "SBO:0000247", "kegg.compound": "C00051"}}, {"charge": 0, "name": "Thymine", "formula": "C5H6N2O2", "compartment": "e", "id": "thym_e", "annotation": {"bigg.metabolite": "thym", "sbo": "SBO:0000247", "kegg.compound": "C00178"}}, {"charge": 0, "name": "5-Methylthioadenosine", "formula": "C11H15N5O3S", "compartment": "e", "id": "5mta_e", "annotation": {"bigg.metabolite": "5mta", "sbo": "SBO:0000247", "kegg.compound": "C00170"}}, {"charge": -4, "name": "\"Adenosine 3',5'-bisphosphate\"", "formula": "C10H11N5O10P2", "compartment": "c", "id": "pap_c", "annotation": {"bigg.metabolite": "pap", "sbo": "SBO:0000247", "kegg.compound": "C00054"}}, {"charge": -2, "name": "CMP", "formula": "C9H12N3O8P", "compartment": "c", "id": "cmp_c", "annotation": {"bigg.metabolite": "cmp", "sbo": "SBO:0000247", "kegg.compound": "C00055"}}, {"charge": -1, "name": "Reduced glutathione", "formula": "C10H16N3O6S", "compartment": "c", "id": "gthrd_c", "annotation": {"bigg.metabolite": "gthrd", "sbo": "SBO:0000247", "kegg.compound": "C00051"}}, {"charge": -2, "name": "UDPgalactose", "formula": "C15H22N2O17P2", "compartment": "c", "id": "udpgal_c", "annotation": {"bigg.metabolite": "udpgal", "sbo": "SBO:0000247", "kegg.compound": "C00052"}}, {"charge": 0, "name": "monoacylglycerol 2 ", "formula": "C20.3018H38.5094O4.0", "compartment": "e", "id": "mag_e", "annotation": {"bigg.metabolite": "mag_hs", "sbo": "SBO:0000247", "kegg.compound": "C01885"}}, {"charge": 1, "name": "Aminoacetone", "formula": "C3H8NO", "compartment": "e", "id": "aact_e", "annotation": {"bigg.metabolite": "aact", "sbo": "SBO:0000247", "kegg.compound": "C01888"}}, {"charge": -1, "name": "Formate", "formula": "CH1O2", "compartment": "c", "id": "for_c", "annotation": {"bigg.metabolite": "for", "sbo": "SBO:0000247", "kegg.compound": "C00058"}}, {"charge": -2, "name": "Sulfate", "formula": "O4S", "compartment": "c", "id": "so4_c", "annotation": {"bigg.metabolite": "so4", "sbo": "SBO:0000247", "kegg.compound": "C00059"}}, {"charge": -1, "name": "Phosphatidylserine", "formula": "C43.1308H74.1556N1.0O10.0P1.0", "compartment": "m", "id": "ps_m", "annotation": {"bigg.metabolite": ["ps181", "ps180", "ps161", "ps160", "ps141", "ps140", "ps120", "ps_SA", "ps_hs", "ps_EC", "ps_HP", "ps_SC"], "sbo": "SBO:0000247", "kegg.compound": "C02737"}}, {"charge": -2, "name": "Glyceraldehyde 3-phosphate", "formula": "C3H5O6P", "compartment": "c", "id": "g3p_c", "annotation": {"bigg.metabolite": "g3p", "sbo": "SBO:0000247", "kegg.compound": "C00118"}}, {"charge": 0, "name": "Retinal", "formula": "C20H28O", "compartment": "c", "id": "retinal_c", "annotation": {"bigg.metabolite": "retinal", "sbo": "SBO:0000247", "kegg.compound": "C00376"}}, {"charge": 0, "name": "Thymidine", "formula": "C10H14N2O5", "compartment": "e", "id": "thymd_e", "annotation": {"bigg.metabolite": "thymd", "sbo": "SBO:0000247", "kegg.compound": "C00214"}}, {"charge": 0, "name": "Adenosine", "formula": "C10H13N5O4", "compartment": "e", "id": "adn_e", "annotation": {"bigg.metabolite": "adn", "sbo": "SBO:0000247", "kegg.compound": "C00212"}}, {"charge": -1, "name": "5-Hydroxyeicosatetraenoate", "formula": "C20H31O3", "compartment": "c", "id": "5HETE_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C04805"}}, {"charge": 0, "name": "Selenomethionine", "formula": "C5H11NO2Se", "compartment": "c", "id": "selmeth_c", "annotation": {"bigg.metabolite": "selmeth", "sbo": "SBO:0000247", "kegg.compound": "C05335"}}, {"charge": -3, "name": "all-trans-Nonaprenyl diphosphate", "formula": "C45H73O7P2", "compartment": "m", "id": "nonadp_m", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C04145"}}, {"charge": 0, "name": "Cytidine", "formula": "C9H13N3O5", "compartment": "m", "id": "cytd_m", "annotation": {"bigg.metabolite": "cytd", "sbo": "SBO:0000247", "kegg.compound": "C00475"}}, {"charge": -1, "name": "\"5-Hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoate\"", "formula": "C20H31O4", "compartment": "c", "id": "5HPET_c", "annotation": {"bigg.metabolite": "5HPET", "sbo": "SBO:0000247", "kegg.compound": "C05356"}}, {"charge": 1, "name": "L-Methionyl-tRNA (Met)", "formula": "C5H11NO2SR", "compartment": "c", "id": "mettrna_c", "annotation": {"bigg.metabolite": "mettrna", "sbo": "SBO:0000247", "kegg.compound": "C02430"}}, {"charge": 0, "name": "Urate", "formula": "C5H4N4O3", "compartment": "e", "id": "urate_e", "annotation": {"bigg.metabolite": "urate", "sbo": "SBO:0000247", "kegg.compound": "C00366"}}, {"charge": -2, "name": "D-Erythrose 4-phosphate", "formula": "C4H7O7P", "compartment": "m", "id": "e4p_m", "annotation": {"bigg.metabolite": "e4p", "sbo": "SBO:0000247", "kegg.compound": "C00279"}}, {"charge": -1, "name": "2-keto-4-methylthiobutyrate", "formula": "C5H7O3S", "compartment": "c", "id": "2kmb_c", "annotation": {"bigg.metabolite": "2kmb", "sbo": "SBO:0000247", "kegg.compound": "C01180"}}, {"charge": -4, "name": "Vaccenyl coenzyme A", "formula": "C39H64N7O17P3S", "compartment": "c", "id": "vacccoa_c", "annotation": {"bigg.metabolite": "vacccoa", "sbo": "SBO:0000247"}}, {"charge": -1, "name": "Fatty acid (C13:iso)", "formula": "C13H25O2", "compartment": "c", "id": "fa13p0iso_c", "annotation": {"bigg.metabolite": ["fa9", "fa6", "fa5", "fa4", "fa3", "fa20n", "fa19a", "fa12", "fa11", "fa10", "fa1"], "sbo": "SBO:0000247"}}, {"charge": 0, "name": "4-Trimethylammoniobutanoate", "formula": "C7H15NO2", "compartment": "c", "id": "4tmeabutn_c", "annotation": {"bigg.metabolite": "4tmeabutn", "sbo": "SBO:0000247", "kegg.compound": "C01181"}}, {"charge": -4, "name": "Palmitoleyl-coA", "formula": "C37H60N7O17P3S", "compartment": "c", "id": "fa16p1n7coa_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -2, "name": "Phosphatidate  (bacteria)", "formula": "C36.171H67.2872O8.0P1.0", "compartment": "c", "id": "pa_BAC_c", "annotation": {"bigg.metabolite": ["pa_SA", "pa_EC"], "sbo": "SBO:0000247"}}, {"charge": 0, "name": "glycogen", "formula": "C6H10O5", "compartment": "c", "id": "glycogen_BAC_c", "annotation": {"bigg.metabolite": "glycogen", "sbo": "SBO:0000247"}}, {"charge": 0, "name": "dodecanoyl carnitine", "formula": "C19H37NO4", "compartment": "c", "id": "ddcrn_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -2, "name": "Cardiolipin (bacteria)", "formula": "C75.342H140.5744O17.0P2.0", "compartment": "c", "id": "clpn_BAC_c", "annotation": {"bigg.metabolite": ["clpn181", "clpn180", "clpn161", "clpn160190", "clpn160", "clpn141", "clpn140", "clpn120", "clpn_SA", "clpn_hs", "clpn_HP", "clpn_EC"], "sbo": "SBO:0000247"}}, {"charge": -1, "name": "Phosphatidylserine (bacteria)", "formula": "C39.171H73.2872N1.0O10.0P1.0", "compartment": "c", "id": "ps_BAC_c", "annotation": {"bigg.metabolite": ["ps181", "ps180", "ps161", "ps160", "ps141", "ps140", "ps120", "ps_SA", "ps_hs", "ps_EC", "ps_HP", "ps_SC"], "sbo": "SBO:0000247"}}, {"charge": 0, "name": "tetradecanoyl carnitine", "formula": "C21H41NO4", "compartment": "c", "id": "ttdcrn_c", "annotation": {"bigg.metabolite": "ttdcrn", "sbo": "SBO:0000247"}}, {"charge": 0, "name": "Electron transfer flavoprotein oxidized", "formula": "R", "compartment": "m", "id": "etfox_m", "annotation": {"bigg.metabolite": "etfox", "sbo": "SBO:0000247", "kegg.compound": "C04253"}}, {"charge": 0, "name": "Xanthosine", "formula": "C10H12N4O6", "compartment": "e", "id": "xtsn_e", "annotation": {"bigg.metabolite": "xtsn", "sbo": "SBO:0000247", "kegg.compound": "C01762"}}, {"charge": -4, "name": "Octadecenoyl-CoA (n-C18:1CoA)", "formula": "C39H64N7O17P3S", "compartment": "m", "id": "odecoa_m", "annotation": {"bigg.metabolite": "odecoa", "sbo": "SBO:0000247", "kegg.compound": "C00510"}}, {"charge": 0, "name": "sn-Glycero-3-phosphoethanolamine", "formula": "C5H14NO6P", "compartment": "c", "id": "g3pe_c", "annotation": {"bigg.metabolite": "g3pe", "sbo": "SBO:0000247", "kegg.compound": "C01233"}}, {"charge": -2, "name": "\"6-phospho-D-glucono-1,5-lactone\"", "formula": "C6H9O9P", "compartment": "c", "id": "6pgl_c", "annotation": {"bigg.metabolite": "6pgl", "sbo": "SBO:0000247", "kegg.compound": "C01236"}}, {"charge": 0, "name": "N-Acetyl-beta-D-glucosaminylamine", "formula": "C8H16N2O5", "compartment": "c", "id": "acBgamam_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C01239"}}, {"charge": -1, "name": "3-4-Dihydroxyphenylacetate", "formula": "C8H7O4", "compartment": "e", "id": "34dhpha_e", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C01161"}}, {"charge": -1, "name": "(R)-S-Lactoylglutathione", "formula": "C13H20N3O8S", "compartment": "m", "id": "lgt-S_m", "annotation": {"bigg.metabolite": "lgt-S", "sbo": "SBO:0000247", "kegg.compound": "C03451"}}, {"charge": 0, "name": "Guanosine", "formula": "C10H13N5O5", "compartment": "e", "id": "gsn_e", "annotation": {"bigg.metabolite": "gsn", "sbo": "SBO:0000247", "kegg.compound": "C00387"}}, {"charge": 0, "name": "Melibiose", "formula": "C12H22O11", "compartment": "e", "id": "melib_e", "annotation": {"bigg.metabolite": "melib", "sbo": "SBO:0000247", "kegg.compound": "C05402"}}, {"charge": 0, "name": "Hydrogen cyanide", "formula": "CHN", "compartment": "c", "id": "cyan_c", "annotation": {"bigg.metabolite": "cyan", "sbo": "SBO:0000247", "kegg.compound": "C01326"}}, {"charge": 0, "name": "Platelet-activating factor", "formula": "C28.0H58.0N1.0O7.0P1.0", "compartment": "c", "id": "paf_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C04598"}}, {"charge": 0, "name": "L-Cystathionine", "formula": "C7H14N2O4S", "compartment": "c", "id": "cyst-L_c", "annotation": {"bigg.metabolite": "cyst-L", "sbo": "SBO:0000247", "kegg.compound": "C02291"}}, {"charge": 0, "name": "Octanoyl carnitine", "formula": "C15H29NO4", "compartment": "m", "id": "occrn_m", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 1, "name": "L-Glutaminyl-tRNA(Gln)", "formula": "C5H10N2O3R", "compartment": "m", "id": "glntrna_m", "annotation": {"bigg.metabolite": "glntrna", "sbo": "SBO:0000247", "kegg.compound": "C02282"}}, {"charge": -4, "name": "Isovaleryl-CoA", "formula": "C26H40N7O17P3S", "compartment": "m", "id": "ivcoa_m", "annotation": {"bigg.metabolite": "ivcoa", "sbo": "SBO:0000247", "kegg.compound": "C02939"}}, {"charge": -2, "name": "3-Sulfino-L-alanine", "formula": "C3H5NO4S", "compartment": "m", "id": "3sala_m", "annotation": {"bigg.metabolite": "3sala", "sbo": "SBO:0000247", "kegg.compound": "C00606"}}, {"charge": -1, "name": "Urocanate", "formula": "C6H5N2O2", "compartment": "e", "id": "urcan_e", "annotation": {"bigg.metabolite": "urcan", "sbo": "SBO:0000247", "kegg.compound": "C00785"}}, {"charge": -1, "name": "5-L-Glutamyl-L-alanine", "formula": "C8H13N2O5", "compartment": "c", "id": "gluala_c", "annotation": {"bigg.metabolite": "gluala", "sbo": "SBO:0000247", "kegg.compound": "C03740"}}, {"charge": 1, "name": "Serotonin", "formula": "C10H13N2O", "compartment": "e", "id": "srtn_e", "annotation": {"bigg.metabolite": "srtn", "sbo": "SBO:0000247", "kegg.compound": "C00780"}}, {"charge": -4, "name": "lignocericyl coenzyme A", "formula": "C45H78N7O17P3S", "compartment": "c", "id": "lgnccoa_c", "annotation": {"bigg.metabolite": "acoa", "sbo": "SBO:0000247"}}, {"charge": 0, "name": "Fatty acyl (C17:iso) carnitine", "formula": "C24H47NO4", "compartment": "c", "id": "fa17p0isocrn_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 0, "name": "Fatty acyl (C9:iso) carnitine", "formula": "C16H31NO4", "compartment": "c", "id": "fa9p0isocrn_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 0, "name": "cis-11,12-methyleneoctadecanoyl carnitine", "formula": "C26H49NO4", "compartment": "c", "id": "fa19c11crn_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 0, "name": "Fatty acyl (C15:iso) carnitine", "formula": "C22H43NO4", "compartment": "c", "id": "fa15p0isocrn_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 0, "name": "cis-3,4-methylenedecanoyl coa", "formula": "C18H33NO4", "compartment": "c", "id": "fa11c3crn_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 0, "name": "cis-9,10-methylenehexadecanoyl carnitine", "formula": "C24H45NO4", "compartment": "c", "id": "fa17c9crn_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 1, "name": "Peptidyl-L-lysine", "formula": "XC6H13N2O", "compartment": "c", "id": "peplys_c", "annotation": {"bigg.metabolite": "peplys", "sbo": "SBO:0000247", "kegg.compound": "C02188"}}, {"charge": 0, "name": "Non-mitochondrial protein", "formula": "C4.8274H7.5773N1.3013O1.5242S0.0124", "compartment": "c", "id": "prot_other_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -4, "name": "Fatty acyl (C15:iso) coa", "formula": "C36H60N7O17P3S", "compartment": "m", "id": "fa15p0isocoa_m", "annotation": {"bigg.metabolite": "acoa", "sbo": "SBO:0000247"}}, {"charge": -1, "name": "3-Nonaprenyl-4-hydroxybenzoate", "formula": "C52H77O3", "compartment": "m", "id": "3nphb_m", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C03885"}}, {"charge": -1, "name": "Phosphatidylglycerol (bacteria)", "formula": "C39.171H74.2872O10.0P1.0", "compartment": "c", "id": "pg_BAC_c", "annotation": {"bigg.metabolite": ["pglyc_hs", "pg190", "pg181", "pg180", "pg161", "pg160190", "pg160", "pg141", "pg140", "pg120", "pg_SA", "pg_EC", "pg_HP", "pg_SC"], "sbo": "SBO:0000247"}}, {"charge": 0, "name": "tRNA(Phe)", "formula": "ROH", "compartment": "m", "id": "trnaphe_m", "annotation": {"bigg.metabolite": "trnaphe", "sbo": "SBO:0000247", "kegg.compound": "C01648"}}, {"charge": 0, "name": "tRNA(Pro)", "formula": "ROH", "compartment": "m", "id": "trnapro_m", "annotation": {"bigg.metabolite": "trnapro", "sbo": "SBO:0000247", "kegg.compound": "C01649"}}, {"charge": -1, "name": "tetradecanoate (n-C14:0)", "formula": "C14H27O2", "compartment": "c", "id": "ttdca_c", "annotation": {"bigg.metabolite": "ttdca", "sbo": "SBO:0000247", "kegg.compound": "C06424"}}, {"charge": 0, "name": "tRNA(Gln)", "formula": "ROH", "compartment": "m", "id": "trnagln_m", "annotation": {"bigg.metabolite": "trnagln", "sbo": "SBO:0000247", "kegg.compound": "C01640"}}, {"charge": 0, "name": "tRNA (Glu)", "formula": "ROH", "compartment": "m", "id": "trnaglu_m", "annotation": {"bigg.metabolite": "trnaglu", "sbo": "SBO:0000247", "kegg.compound": "C01641"}}, {"charge": 0, "name": "tRNA(Gly)", "formula": "ROH", "compartment": "m", "id": "trnagly_m", "annotation": {"bigg.metabolite": "trnagly", "sbo": "SBO:0000247", "kegg.compound": "C01642"}}, {"charge": 0, "name": "tRNA(His)", "formula": "ROH", "compartment": "m", "id": "trnahis_m", "annotation": {"bigg.metabolite": "trnahis", "sbo": "SBO:0000247", "kegg.compound": "C01643"}}, {"charge": 0, "name": "tRNA(Ile)", "formula": "ROH", "compartment": "m", "id": "trnaile_m", "annotation": {"bigg.metabolite": "trnaile", "sbo": "SBO:0000247", "kegg.compound": "C01644"}}, {"charge": 0, "name": "tRNA(Leu)", "formula": "ROH", "compartment": "m", "id": "trnaleu_m", "annotation": {"bigg.metabolite": "trnaleu", "sbo": "SBO:0000247", "kegg.compound": "C01645"}}, {"charge": 0, "name": "tRNA(Lys)", "formula": "ROH", "compartment": "m", "id": "trnalys_m", "annotation": {"bigg.metabolite": "trnalys", "sbo": "SBO:0000247", "kegg.compound": "C01646"}}, {"charge": 0, "name": "tRNA(Met)", "formula": "ROH", "compartment": "m", "id": "trnamet_m", "annotation": {"bigg.metabolite": "trnamet", "sbo": "SBO:0000247", "kegg.compound": "C01647"}}, {"charge": -1, "name": "enol-Phenylpyruvate", "formula": "C9H7O3", "compartment": "c", "id": "enphpyr_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C02763"}}, {"charge": 1, "name": "L-Histidyl-tRNA(His)", "formula": "C6H9N3O2R", "compartment": "c", "id": "histrna_c", "annotation": {"bigg.metabolite": "histrna", "sbo": "SBO:0000247", "kegg.compound": "C02988"}}, {"charge": 0, "name": "L-Aspartyl-tRNA(Asp)", "formula": "C4H6NO4R", "compartment": "c", "id": "asptrna_c", "annotation": {"bigg.metabolite": "asptrna", "sbo": "SBO:0000247", "kegg.compound": "C02984"}}, {"charge": -2, "name": "L-Fucose 1-phosphate", "formula": "C6H11O8P", "compartment": "c", "id": "fuc1p-L_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C02985"}}, {"charge": 0, "name": "L-Glutamyl-tRNA(Glu)", "formula": "C5H8NO4R", "compartment": "c", "id": "glutrna_c", "annotation": {"bigg.metabolite": "glutrna", "sbo": "SBO:0000247", "kegg.compound": "C02987"}}, {"charge": 0, "name": "Peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine", "formula": "XC12O7N3H19", "compartment": "c", "id": "pepasp_acgamam_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C04375"}}, {"charge": -2, "name": "N2-Formyl-N1-(5-phospho-D-ribosyl)glycinamide", "formula": "C8H13N2O9P", "compartment": "c", "id": "fgam_c", "annotation": {"bigg.metabolite": "fgam", "sbo": "SBO:0000247", "kegg.compound": "C04376"}}, {"charge": -1, "name": "(R)-Pantothenate", "formula": "C9H16NO5", "compartment": "c", "id": "pnto-R_c", "annotation": {"bigg.metabolite": "pnto-R", "sbo": "SBO:0000247", "kegg.compound": "C00864"}}, {"charge": 0, "name": "Dopaquinone", "formula": "C9H9NO4", "compartment": "c", "id": "dopaqn_c", "annotation": {"bigg.metabolite": "dopaqn", "sbo": "SBO:0000247", "kegg.compound": "C00822"}}, {"charge": 0, "name": "Deoxyinosine", "formula": "C10H12N4O4", "compartment": "c", "id": "din_c", "annotation": {"bigg.metabolite": "din", "sbo": "SBO:0000247", "kegg.compound": "C05512"}}, {"charge": 0, "name": "L-Allo-threonine", "formula": "C4H9NO3", "compartment": "c", "id": "athr-L_c", "annotation": {"bigg.metabolite": "athr-L", "sbo": "SBO:0000247", "kegg.compound": "C05519"}}, {"charge": -2, "name": "1-Alkyl-sn-glycerol 3-phosphate", "formula": "C21.0H43.0O6.0P1.0", "compartment": "c", "id": "akgp_c", "annotation": {"bigg.metabolite": "akgp_hs", "sbo": "SBO:0000247", "kegg.compound": "C03968"}}, {"charge": -4, "name": "timnodonyl coenzyme A", "formula": "C41H60N7O17P3S", "compartment": "m", "id": "tmndnccoa_m", "annotation": {"bigg.metabolite": "tmndnccoa", "sbo": "SBO:0000247", "kegg.compound": "C16165"}}, {"charge": -4, "name": "eicosatetranoyl coenzyme A", "formula": "C41H62N7O17P3S", "compartment": "m", "id": "eicostetcoa_m", "annotation": {"bigg.metabolite": "eicostetcoa", "sbo": "SBO:0000247", "kegg.compound": "C16164"}}, {"charge": -2, "name": "CDP diacylglycerol ", "formula": "C49.1308H80.1556N3.0O15.0P2.0", "compartment": "c", "id": "cdpdag_c", "annotation": {"bigg.metabolite": "cdpdag_hs", "sbo": "SBO:0000247", "kegg.compound": "C00269"}}, {"charge": 0, "name": "\"6,7-Dihydrobiopterin\"", "formula": "C9H13N5O3", "compartment": "c", "id": "dhbpt_c", "annotation": {"bigg.metabolite": "dhbpt", "sbo": "SBO:0000247", "kegg.compound": "C00268"}}, {"charge": 0, "name": "Hypoxanthine", "formula": "C5H4N4O", "compartment": "c", "id": "hxan_c", "annotation": {"bigg.metabolite": "hxan", "sbo": "SBO:0000247", "kegg.compound": "C00262"}}, {"charge": -4, "name": "2-Methylprop-2-enoyl-CoA", "formula": "C25H36N7O17P3S", "compartment": "m", "id": "2mp2coa_m", "annotation": {"bigg.metabolite": "2mp2coa", "sbo": "SBO:0000247", "kegg.compound": "C03460"}}, {"charge": 0, "name": "alpha-D-Glucose", "formula": "C6H12O6", "compartment": "c", "id": "glc-D-A_c", "annotation": {"bigg.metabolite": "glc-D", "sbo": "SBO:0000247", "kegg.compound": "C00267"}}, {"charge": 0, "name": "Glycolaldehyde", "formula": "C2H4O2", "compartment": "c", "id": "gcald_c", "annotation": {"bigg.metabolite": "gcald", "sbo": "SBO:0000247", "kegg.compound": "C00266"}}, {"charge": 0, "name": "Ethanol", "formula": "C2H6O", "compartment": "c", "id": "etoh_c", "annotation": {"bigg.metabolite": "etoh", "sbo": "SBO:0000247", "kegg.compound": "C00469"}}, {"charge": 0, "name": "Chitin (monomer)", "formula": "C8H13NO5", "compartment": "c", "id": "chitin_c", "annotation": {"bigg.metabolite": "chitin", "sbo": "SBO:0000247", "kegg.compound": "C00461"}}, {"charge": -4, "name": "dUTP", "formula": "C9H11N2O14P3", "compartment": "c", "id": "dutp_c", "annotation": {"bigg.metabolite": "dutp", "sbo": "SBO:0000247", "kegg.compound": "C00460"}}, {"charge": -4, "name": "dGTP", "formula": "C10H12N5O13P3", "compartment": "c", "id": "dgtp_c", "annotation": {"bigg.metabolite": "dgtp", "sbo": "SBO:0000247", "kegg.compound": "C00286"}}, {"charge": 0, "name": "Adenosine", "formula": "C10H13N5O4", "compartment": "m", "id": "adn_m", "annotation": {"bigg.metabolite": "adn", "sbo": "SBO:0000247", "kegg.compound": "C00212"}}, {"charge": 0, "name": "Hydrogen sulfide", "formula": "H2S", "compartment": "c", "id": "h2s_c", "annotation": {"bigg.metabolite": "h2s", "sbo": "SBO:0000247", "kegg.compound": "C00283"}}, {"charge": -1, "name": "Bicarbonate", "formula": "CHO3", "compartment": "c", "id": "hco3_c", "annotation": {"bigg.metabolite": "hco3", "sbo": "SBO:0000247", "kegg.compound": "C00288"}}, {"charge": -1, "name": "Vaccenic acid", "formula": "C18H33O2", "compartment": "e", "id": "vacc_e", "annotation": {"bigg.metabolite": "vacc", "sbo": "SBO:0000247"}}, {"charge": 2, "name": "Fe2+", "formula": "Fe", "compartment": "m", "id": "fe2_m", "annotation": {"bigg.metabolite": "fe2", "sbo": "SBO:0000247", "kegg.compound": "C14818"}}, {"charge": 0, "name": "Selenocysteine", "formula": "C3H7NO2Se", "compartment": "c", "id": "selcys_c", "annotation": {"bigg.metabolite": "selcys", "sbo": "SBO:0000247", "kegg.compound": "C05688"}}, {"charge": 0, "name": "Dehydroascorbate", "formula": "C6H6O6", "compartment": "c", "id": "dhdascb_c", "annotation": {"bigg.metabolite": "dhdascb", "sbo": "SBO:0000247", "kegg.compound": "C05422"}}, {"charge": 0, "name": "Eicosatetranoyl carnitine", "formula": "C27H45NO4", "compartment": "c", "id": "eicostetcrn_c", "annotation": {"bigg.metabolite": "eicostetcrn", "sbo": "SBO:0000247"}}, {"charge": -2, "name": "(S)-2-Hydroxyglutarate", "formula": "C5H6O5", "compartment": "m", "id": "2hglut_m", "annotation": {"bigg.metabolite": "S2hglut", "sbo": "SBO:0000247", "kegg.compound": "C02630"}}, {"charge": -2, "name": "3-Sulfino-L-alanine", "formula": "C3H5NO4S", "compartment": "c", "id": "3sala_c", "annotation": {"bigg.metabolite": "3sala", "sbo": "SBO:0000247", "kegg.compound": "C00606"}}, {"charge": -1, "name": "Bicarbonate", "formula": "CHO3", "compartment": "m", "id": "hco3_m", "annotation": {"bigg.metabolite": "hco3", "sbo": "SBO:0000247", "kegg.compound": "C00288"}}, {"charge": 0, "name": "Deoxyadenosine", "formula": "C10H13N5O3", "compartment": "e", "id": "dad-2_e", "annotation": {"bigg.metabolite": "dad-2", "sbo": "SBO:0000247", "kegg.compound": "C00559"}}, {"charge": 0, "name": "myo-Inositol", "formula": "C6H12O6", "compartment": "c", "id": "inost_c", "annotation": {"bigg.metabolite": "inost", "sbo": "SBO:0000247", "kegg.compound": "C00137"}}, {"charge": 0, "name": "L-Histidine", "formula": "C6H9N3O2", "compartment": "c", "id": "his-L_c", "annotation": {"bigg.metabolite": "his-L", "sbo": "SBO:0000247", "kegg.compound": "C00135"}}, {"charge": 2, "name": "Putrescine", "formula": "C4H14N2", "compartment": "c", "id": "ptrc_c", "annotation": {"bigg.metabolite": "ptrc", "sbo": "SBO:0000247", "kegg.compound": "C00134"}}, {"charge": 0, "name": "D-Alanine", "formula": "C3H7NO2", "compartment": "c", "id": "ala-D_c", "annotation": {"bigg.metabolite": "ala-D", "sbo": "SBO:0000247", "kegg.compound": "C00133"}}, {"charge": 0, "name": "Methanol", "formula": "CH4O1", "compartment": "c", "id": "meoh_c", "annotation": {"bigg.metabolite": "meoh", "sbo": "SBO:0000247", "kegg.compound": "C00132"}}, {"charge": -4, "name": "dATP", "formula": "C10H12N5O12P3", "compartment": "c", "id": "datp_c", "annotation": {"bigg.metabolite": "datp", "sbo": "SBO:0000247", "kegg.compound": "C00131"}}, {"charge": -2, "name": "IMP", "formula": "C10H11N4O8P", "compartment": "c", "id": "imp_c", "annotation": {"bigg.metabolite": "imp", "sbo": "SBO:0000247", "kegg.compound": "C00130"}}, {"charge": 0, "name": "Adenine", "formula": "C5H5N5", "compartment": "e", "id": "ade_e", "annotation": {"bigg.metabolite": "ade", "sbo": "SBO:0000247", "kegg.compound": "C00147"}}, {"charge": 0, "name": "N-Acetyl-D-glucosamine", "formula": "C8H15NO6", "compartment": "e", "id": "acgam_e", "annotation": {"bigg.metabolite": "acgam", "sbo": "SBO:0000247", "kegg.compound": "C00140"}}, {"charge": -1, "name": "Glyoxylate", "formula": "C2H1O3", "compartment": "m", "id": "glx_m", "annotation": {"bigg.metabolite": "glx", "sbo": "SBO:0000247", "kegg.compound": "C00048"}}, {"charge": 0, "name": "Dehydroascorbate", "formula": "C6H6O6", "compartment": "e", "id": "dhdascb_e", "annotation": {"bigg.metabolite": "dhdascb", "sbo": "SBO:0000247", "kegg.compound": "C05422"}}, {"charge": -2, "name": "\"5,10-Methylenetetrahydrofolate\"", "formula": "C20H21N7O6", "compartment": "e", "id": "mlthf_e", "annotation": {"bigg.metabolite": "mlthf", "sbo": "SBO:0000247", "kegg.compound": "C00143"}}, {"charge": -4, "name": "GTP", "formula": "C10H12N5O14P3", "compartment": "m", "id": "gtp_m", "annotation": {"bigg.metabolite": "gtp", "sbo": "SBO:0000247", "kegg.compound": "C00044"}}, {"charge": 1, "name": "L-Lysine", "formula": "C6H15N2O2", "compartment": "m", "id": "lys-L_m", "annotation": {"bigg.metabolite": "lys-L", "sbo": "SBO:0000247", "kegg.compound": "C00047"}}, {"charge": 0, "name": "L-Alanine", "formula": "C3H7NO2", "compartment": "m", "id": "ala-L_m", "annotation": {"bigg.metabolite": "ala-L", "sbo": "SBO:0000247", "kegg.compound": "C00041"}}, {"charge": -2, "name": "L-Malate", "formula": "C4H4O5", "compartment": "e", "id": "mal-L_e", "annotation": {"bigg.metabolite": "mal-L", "sbo": "SBO:0000247", "kegg.compound": "C00149"}}, {"charge": -2, "name": "Succinate", "formula": "C4H4O4", "compartment": "m", "id": "succ_m", "annotation": {"bigg.metabolite": "succ", "sbo": "SBO:0000247", "kegg.compound": "C00042"}}, {"charge": 1, "name": "L-Prolyl-tRNA(Pro)", "formula": "C5H9NO2R", "compartment": "m", "id": "protrna_m", "annotation": {"bigg.metabolite": "protrna", "sbo": "SBO:0000247", "kegg.compound": "C02702"}}, {"charge": 0, "name": "Stearoylcarnitine", "formula": "C25H49NO4", "compartment": "c", "id": "stcrn_c", "annotation": {"bigg.metabolite": "stcrn", "sbo": "SBO:0000247"}}, {"charge": -2, "name": "UDP-N-acetyl-D-glucosamine", "formula": "C17H25N3O17P2", "compartment": "c", "id": "uacgam_c", "annotation": {"bigg.metabolite": "uacgam", "sbo": "SBO:0000247", "kegg.compound": "C00043"}}, {"charge": -2, "name": "Succinate", "formula": "C4H4O4", "compartment": "c", "id": "succ_c", "annotation": {"bigg.metabolite": "succ", "sbo": "SBO:0000247", "kegg.compound": "C00042"}}, {"charge": 0, "name": "L-Alanine", "formula": "C3H7NO2", "compartment": "c", "id": "ala-L_c", "annotation": {"bigg.metabolite": "ala-L", "sbo": "SBO:0000247", "kegg.compound": "C00041"}}, {"charge": -4, "name": "R total Coenzyme A", "formula": "C39.5654H62.5778N7.0O17.0P3.0S1.0", "compartment": "c", "id": "Rtotalcoa_c", "annotation": {"bigg.metabolite": "Rtotalcoa", "sbo": "SBO:0000247", "kegg.compound": "C00040"}}, {"charge": 1, "name": "L-Lysine", "formula": "C6H15N2O2", "compartment": "c", "id": "lys-L_c", "annotation": {"bigg.metabolite": "lys-L", "sbo": "SBO:0000247", "kegg.compound": "C00047"}}, {"charge": -4, "name": "GTP", "formula": "C10H12N5O14P3", "compartment": "c", "id": "gtp_c", "annotation": {"bigg.metabolite": "gtp", "sbo": "SBO:0000247", "kegg.compound": "C00044"}}, {"charge": -1, "name": "L-Aspartate", "formula": "C4H6NO4", "compartment": "c", "id": "asp-L_c", "annotation": {"bigg.metabolite": "asp-L", "sbo": "SBO:0000247", "kegg.compound": "C00049"}}, {"charge": -1, "name": "Glyoxylate", "formula": "C2H1O3", "compartment": "c", "id": "glx_c", "annotation": {"bigg.metabolite": "glx", "sbo": "SBO:0000247", "kegg.compound": "C00048"}}, {"charge": 0, "name": "Protein-cysteine", "formula": "C5H9N2O3SR(C2H2NOR)n(C2H2NOR)n", "compartment": "c", "id": "protCys_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C20119"}}, {"charge": 1, "name": "S-Aminomethyldihydrolipoylprotein", "formula": "CH6NS2X", "compartment": "m", "id": "alpro_m", "annotation": {"bigg.metabolite": "alpro", "sbo": "SBO:0000247", "kegg.compound": "C01242"}}, {"charge": 0, "name": "Maltose", "formula": "C12H22O11", "compartment": "e", "id": "malt_e", "annotation": {"bigg.metabolite": "malt", "sbo": "SBO:0000247", "kegg.compound": "C00208"}}, {"charge": 0, "name": "Protein C-terminal S-farnesyl-L-cysteine methyl ester", "formula": "C21H35N2O3SR(C2H2NOR)n", "compartment": "c", "id": "protSfarCmet_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C04748"}}, {"charge": 1, "name": "Phenethylamine", "formula": "C8H12N", "compartment": "e", "id": "peamn_e", "annotation": {"bigg.metabolite": "peamn", "sbo": "SBO:0000247", "kegg.compound": "C05332"}}, {"charge": -1, "name": "\"4-(2-Amino-3-hydroxyphenyl)-2,4-dioxobutanoate\"", "formula": "C10H8NO5", "compartment": "c", "id": "42A3HP24DB_c", "annotation": {"bigg.metabolite": "42A3HP24DB", "sbo": "SBO:0000247", "kegg.compound": "C05645"}}, {"charge": 0, "name": "Selenomethionine", "formula": "C5H11NO2Se", "compartment": "e", "id": "selmeth_e", "annotation": {"bigg.metabolite": "selmeth", "sbo": "SBO:0000247", "kegg.compound": "C05335"}}, {"charge": -2, "name": "Cinnavalininate", "formula": "C14H6N2O6", "compartment": "c", "id": "cinnavalininate_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C05640"}}, {"charge": 1, "name": "Glycyl-tRNA(Gly)", "formula": "C2H5NO2R", "compartment": "m", "id": "glytrna_m", "annotation": {"bigg.metabolite": "glytrna", "sbo": "SBO:0000247", "kegg.compound": "C02412"}}, {"charge": 0, "name": "tRNA(Val)", "formula": "ROH", "compartment": "c", "id": "trnaval_c", "annotation": {"bigg.metabolite": "trnaval", "sbo": "SBO:0000247", "kegg.compound": "C01653"}}, {"charge": 0, "name": "1-(1-Alkenyl)-sn-glycerol", "formula": "C21.0H42.0O3.0", "compartment": "c", "id": "alkenglyc_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C15645"}}, {"charge": 0, "name": "Retinal", "formula": "C20H28O", "compartment": "e", "id": "retinal_e", "annotation": {"bigg.metabolite": "retinal", "sbo": "SBO:0000247", "kegg.compound": "C00376"}}, {"charge": -4, "name": "dUTP", "formula": "C9H11N2O14P3", "compartment": "m", "id": "dutp_m", "annotation": {"bigg.metabolite": "dutp", "sbo": "SBO:0000247", "kegg.compound": "C00460"}}, {"charge": 1, "name": "Histamine", "formula": "C5H10N3", "compartment": "c", "id": "hista_c", "annotation": {"bigg.metabolite": "hista", "sbo": "SBO:0000247", "kegg.compound": "C00388"}}, {"charge": 0, "name": "Ethanol", "formula": "C2H6O", "compartment": "m", "id": "etoh_m", "annotation": {"bigg.metabolite": "etoh", "sbo": "SBO:0000247", "kegg.compound": "C00469"}}, {"charge": 0, "name": "Xylitol", "formula": "C5H12O5", "compartment": "e", "id": "xylt_e", "annotation": {"bigg.metabolite": "xylt", "sbo": "SBO:0000247", "kegg.compound": "C00379"}}, {"charge": 1, "name": "Thiamin", "formula": "C12H17N4OS", "compartment": "e", "id": "thm_e", "annotation": {"bigg.metabolite": "thm", "sbo": "SBO:0000247", "kegg.compound": "C00378"}}, {"charge": 0, "name": "Glycolaldehyde", "formula": "C2H4O2", "compartment": "m", "id": "gcald_m", "annotation": {"bigg.metabolite": "gcald", "sbo": "SBO:0000247", "kegg.compound": "C00266"}}, {"charge": -2, "name": "CDP diacylglycerol ", "formula": "C49.1308H80.1556N3.0O15.0P2.0", "compartment": "m", "id": "cdpdag_m", "annotation": {"bigg.metabolite": "cdpdag_hs", "sbo": "SBO:0000247", "kegg.compound": "C00269"}}, {"charge": -1, "name": "cis-11,12-methyleneoctadecanoic acid", "formula": "C19H35O2", "compartment": "c", "id": "fa19c11_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -1, "name": "cis-9,10-methylenehexadecanoic acid", "formula": "C17H31O2", "compartment": "c", "id": "fa17c9_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 0, "name": "Apohemeprotein", "formula": "X", "compartment": "c", "id": "apohemeprotein_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 0, "name": "Hemeprotein", "formula": "C34H30FeN4O4X", "compartment": "c", "id": "hemeprotein_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -1, "name": "Palmitoleic acid", "formula": "C16H29O2", "compartment": "c", "id": "fa16p1n7_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -1, "name": "R total from bacterial diet", "formula": "C16.5855H31.1436O2.0", "compartment": "c", "id": "Rtotal_BAC_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -1, "name": "Fatty acid (C17:iso)", "formula": "C17H33O2", "compartment": "c", "id": "fa17p0iso_c", "annotation": {"bigg.metabolite": ["fa9", "fa6", "fa5", "fa4", "fa3", "fa20n", "fa19a", "fa12", "fa11", "fa10", "fa1"], "sbo": "SBO:0000247"}}, {"charge": 0, "name": "Xanthine", "formula": "C5H4N4O2", "compartment": "e", "id": "xan_e", "annotation": {"bigg.metabolite": "xan", "sbo": "SBO:0000247", "kegg.compound": "C00385"}}, {"charge": -1, "name": "Beta cyanoalanine", "formula": "C4H5N2O2", "compartment": "c", "id": "cyanala_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C02512"}}, {"charge": 0, "name": "Trehalose", "formula": "C12H22O11", "compartment": "c", "id": "tre_c", "annotation": {"bigg.metabolite": "tre", "sbo": "SBO:0000247", "kegg.compound": "C01083"}}, {"charge": -4, "name": "cis-11,12-methyleneoctadecanoyl coa", "formula": "C40H66N7O17P3S", "compartment": "m", "id": "fa19c11coa_m", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -4, "name": "cis-9,10-methylenehexadecanoyl coa", "formula": "C38H62N7O17P3S", "compartment": "m", "id": "fa17c9coa_m", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -4, "name": "Intermediary fatty acid C8:1", "formula": "C29H44N7O17P3S", "compartment": "m", "id": "fa8p1n3coa_m", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -4, "name": "Intermediary fatty acid C16:3", "formula": "C37H56N7O17P3S", "compartment": "m", "id": "fa16p3n6coa_m", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 0, "name": "Fatty acyl C8:1 carnitine", "formula": "C15H27NO4", "compartment": "m", "id": "fa8p1n3crn_m", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -4, "name": "Intermediary fatty acid C16:4", "formula": "C37H54N7O17P3S", "compartment": "m", "id": "fa16p4n3coa_m", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -4, "name": "Fatty acyl (C17:iso) coa", "formula": "C38H64N7O17P3S", "compartment": "m", "id": "fa17p0isocoa_m", "annotation": {"bigg.metabolite": "acoa", "sbo": "SBO:0000247"}}, {"charge": 1, "name": "L-Glutaminyl-tRNA(Gln)", "formula": "C5H10N2O3R", "compartment": "c", "id": "glntrna_c", "annotation": {"bigg.metabolite": "glntrna", "sbo": "SBO:0000247", "kegg.compound": "C02282"}}, {"charge": -4, "name": "cis-3,4-methylenedecanoyl coa", "formula": "C32H50N7O17P3S", "compartment": "m", "id": "fa11c3coa_m", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -4, "name": "Fatty acyl (C9:iso) coa", "formula": "C30H48N7O17P3S", "compartment": "m", "id": "fa9p0isocoa_m", "annotation": {"bigg.metabolite": "acoa", "sbo": "SBO:0000247"}}, {"charge": -1, "name": "(S)-3-Methyl-2-oxopentanoate", "formula": "C6H9O3", "compartment": "m", "id": "3mop_m", "annotation": {"bigg.metabolite": "3mop", "sbo": "SBO:0000247", "kegg.compound": "C00671"}}, {"charge": 0, "name": "D-Sorbitol", "formula": "C6H14O6", "compartment": "e", "id": "sbt-D_e", "annotation": {"bigg.metabolite": "sbt-D", "sbo": "SBO:0000247", "kegg.compound": "C00794"}}, {"charge": 1, "name": "Aminoacetone", "formula": "C3H8NO", "compartment": "c", "id": "aact_c", "annotation": {"bigg.metabolite": "aact", "sbo": "SBO:0000247", "kegg.compound": "C01888"}}, {"charge": 0, "name": "Timnodonyl carnitine", "formula": "C27H43NO4", "compartment": "c", "id": "tmndnccrn_c", "annotation": {"bigg.metabolite": "tmndnccrn", "sbo": "SBO:0000247"}}, {"charge": 0, "name": "C20:4 carnitine", "formula": "C27H45NO4", "compartment": "c", "id": "arachdcrn_c", "annotation": {"bigg.metabolite": "arachdcrn", "sbo": "SBO:0000247"}}, {"charge": 0, "name": "Octadecenoyl carnitine", "formula": "C25H47NO4", "compartment": "c", "id": "odecrn_c", "annotation": {"bigg.metabolite": "odecrn", "sbo": "SBO:0000247"}}, {"charge": 0, "name": "Vaccenyl carnitine", "formula": "C25H47NO4", "compartment": "c", "id": "vacccrn_c", "annotation": {"bigg.metabolite": "vacccrn", "sbo": "SBO:0000247"}}, {"charge": 0, "name": "dihomo-gamma-linolenyl carnitine", "formula": "C27H47NO4", "compartment": "c", "id": "dlnlcgcrn_c", "annotation": {"bigg.metabolite": "dlnlcgcrn", "sbo": "SBO:0000247"}}, {"charge": 0, "name": "Linoleyl carnitine", "formula": "C25H45NO4", "compartment": "c", "id": "lnlccrn_c", "annotation": {"bigg.metabolite": "lnlccrn", "sbo": "SBO:0000247"}}, {"charge": 0, "name": "Palmitoleyl carnitine", "formula": "C23H43NO4", "compartment": "c", "id": "fa16p1n7crn_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 0, "name": "monoacylglycerol 2 ", "formula": "C20.3018H38.5094O4.0", "compartment": "c", "id": "mag_c", "annotation": {"bigg.metabolite": "mag_hs", "sbo": "SBO:0000247", "kegg.compound": "C01885"}}, {"charge": -2, "name": "dTMP", "formula": "C10H13N2O8P", "compartment": "c", "id": "dtmp_c", "annotation": {"bigg.metabolite": "dtmp", "sbo": "SBO:0000247", "kegg.compound": "C00364"}}, {"charge": -2, "name": "dUMP", "formula": "C9H11N2O8P", "compartment": "c", "id": "dump_c", "annotation": {"bigg.metabolite": "dump", "sbo": "SBO:0000247", "kegg.compound": "C00365"}}, {"charge": 0, "name": "tRNA(Val)", "formula": "ROH", "compartment": "m", "id": "trnaval_m", "annotation": {"bigg.metabolite": "trnaval", "sbo": "SBO:0000247", "kegg.compound": "C01653"}}, {"charge": 0, "name": "tRNA(Trp)", "formula": "ROH", "compartment": "m", "id": "trnatrp_m", "annotation": {"bigg.metabolite": "trnatrp", "sbo": "SBO:0000247", "kegg.compound": "C01652"}}, {"charge": 0, "name": "tRNA(Thr)", "formula": "ROH", "compartment": "m", "id": "trnathr_m", "annotation": {"bigg.metabolite": "trnathr", "sbo": "SBO:0000247", "kegg.compound": "C01651"}}, {"charge": 0, "name": "tRNA(Ser)", "formula": "ROH", "compartment": "m", "id": "trnaser_m", "annotation": {"bigg.metabolite": "trnaser", "sbo": "SBO:0000247", "kegg.compound": "C01650"}}, {"charge": -2, "name": "dGMP", "formula": "C10H12N5O7P", "compartment": "c", "id": "dgmp_c", "annotation": {"bigg.metabolite": "dgmp", "sbo": "SBO:0000247", "kegg.compound": "C00362"}}, {"charge": -2, "name": "dAMP", "formula": "C10H12N5O6P", "compartment": "c", "id": "damp_c", "annotation": {"bigg.metabolite": "damp", "sbo": "SBO:0000247", "kegg.compound": "C00360"}}, {"charge": -1, "name": "Superoxide anion", "formula": "O2", "compartment": "m", "id": "o2s_m", "annotation": {"bigg.metabolite": "o2s", "sbo": "SBO:0000247", "kegg.compound": "C00704"}}, {"charge": -3, "name": "dCDP", "formula": "C9H12N3O10P2", "compartment": "m", "id": "dcdp_m", "annotation": {"bigg.metabolite": "dcdp", "sbo": "SBO:0000247", "kegg.compound": "C00705"}}, {"charge": -3, "name": "Nicotinamide adenine dinucleotide phosphate", "formula": "C21H25N7O17P3", "compartment": "c", "id": "nadp_c", "annotation": {"bigg.metabolite": "nadp", "sbo": "SBO:0000247", "kegg.compound": "C00006"}}, {"charge": 1, "name": "L-Threonyl-tRNA(Thr)", "formula": "C4H9NO3R", "compartment": "c", "id": "thrtrna_c", "annotation": {"bigg.metabolite": "thrtrna", "sbo": "SBO:0000247", "kegg.compound": "C02992"}}, {"charge": 0, "name": "L-Palmitoylcarnitine", "formula": "C23H45NO4", "compartment": "c", "id": "pmtcrn_c", "annotation": {"bigg.metabolite": "pmtcrn", "sbo": "SBO:0000247", "kegg.compound": "C02990"}}, {"charge": -3, "name": "dGDP", "formula": "C10H12N5O10P2", "compartment": "m", "id": "dgdp_m", "annotation": {"bigg.metabolite": "dgdp", "sbo": "SBO:0000247", "kegg.compound": "C00361"}}, {"charge": 0, "name": "Phosphatidylcholine", "formula": "C45.1308H81.1556N1.0O8.0P1.0", "compartment": "m", "id": "pchol_m", "annotation": {"bigg.metabolite": ["pchol_hs", "pc_EC", "pc_SC"], "sbo": "SBO:0000247", "kegg.compound": "C00157"}}, {"charge": -1, "name": "4-Hydroxybenzoate", "formula": "C7H5O3", "compartment": "m", "id": "4hbz_m", "annotation": {"bigg.metabolite": "4hbz", "sbo": "SBO:0000247", "kegg.compound": "C00156"}}, {"charge": -3, "name": "dTDP", "formula": "C10H13N2O11P2", "compartment": "m", "id": "dtdp_m", "annotation": {"bigg.metabolite": "dtdp", "sbo": "SBO:0000247", "kegg.compound": "C00363"}}, {"charge": -2, "name": "Deamino-NAD+", "formula": "C21H24N6O15P2", "compartment": "c", "id": "dnad_c", "annotation": {"bigg.metabolite": "dnad", "sbo": "SBO:0000247", "kegg.compound": "C00857"}}, {"charge": -1, "name": "Cob(I)alamin", "formula": "C62H88CoN13O14P", "compartment": "c", "id": "cbl1_c", "annotation": {"bigg.metabolite": "cbl1", "sbo": "SBO:0000247", "kegg.compound": "C00853"}}, {"charge": -1, "name": "5-Methyltetrahydrofolate", "formula": "C20H24N7O6", "compartment": "m", "id": "5mthf_m", "annotation": {"bigg.metabolite": "5mthf", "sbo": "SBO:0000247", "kegg.compound": "C00440"}}, {"charge": -1, "name": "trans-4-Hydroxycinnamate", "formula": "C9H7O3", "compartment": "m", "id": "T4hcinnm_m", "annotation": {"bigg.metabolite": "T4hcinnm", "sbo": "SBO:0000247", "kegg.compound": "C00811"}}, {"charge": 1, "name": "N6,N6,N6-Trimethyl-L-lysine", "formula": "C9H21N2O2", "compartment": "e", "id": "tmlys_e", "annotation": {"bigg.metabolite": "tmlys", "sbo": "SBO:0000247", "kegg.compound": "C03793"}}, {"charge": -1, "name": "Peptide 3-hydroxy-L-aspartate", "formula": "XC4H4NO4", "compartment": "c", "id": "pepasp3oh_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C03957"}}, {"charge": 0, "name": "Deoxyinosine", "formula": "C10H12N4O4", "compartment": "e", "id": "din_e", "annotation": {"bigg.metabolite": "din", "sbo": "SBO:0000247", "kegg.compound": "C05512"}}, {"charge": 0, "name": "Deoxyguanosine", "formula": "C10H13N5O4", "compartment": "e", "id": "dgsn_e", "annotation": {"bigg.metabolite": "dgsn", "sbo": "SBO:0000247", "kegg.compound": "C00330"}}, {"charge": -4, "name": "Hexanoyl-CoA (n-C6:0CoA)", "formula": "C27H42N7O17P3S", "compartment": "e", "id": "hxcoa_e", "annotation": {"bigg.metabolite": "hxcoa", "sbo": "SBO:0000247", "kegg.compound": "C05270"}}, {"charge": -2, "name": "5-Formyltetrahydrofolate", "formula": "C20H21N7O7", "compartment": "m", "id": "5fthf_m", "annotation": {"bigg.metabolite": "5fthf", "sbo": "SBO:0000247", "kegg.compound": "C03479"}}, {"charge": 0, "name": "androsterone glucuronide", "formula": "C25H38O8", "compartment": "c", "id": "andrstrnglc_c", "annotation": {"bigg.metabolite": "andrstrnglc", "sbo": "SBO:0000247", "kegg.compound": "C11135"}}, {"charge": -4, "name": "dCTP", "formula": "C9H12N3O13P3", "compartment": "c", "id": "dctp_c", "annotation": {"bigg.metabolite": "dctp", "sbo": "SBO:0000247", "kegg.compound": "C00458"}}, {"charge": -4, "name": "dTTP", "formula": "C10H13N2O14P3", "compartment": "c", "id": "dttp_c", "annotation": {"bigg.metabolite": "dttp", "sbo": "SBO:0000247", "kegg.compound": "C00459"}}, {"charge": 0, "name": "O-Acetyl-L-serine", "formula": "C5H9NO4", "compartment": "e", "id": "acser_e", "annotation": {"bigg.metabolite": "acser", "sbo": "SBO:0000247", "kegg.compound": "C00979"}}, {"charge": -1, "name": "NMN", "formula": "C11H14N2O8P", "compartment": "c", "id": "nmn_c", "annotation": {"bigg.metabolite": "nmn", "sbo": "SBO:0000247", "kegg.compound": "C00455"}}, {"charge": -1, "name": "3-Hydroxy-2-methylpropanoate", "formula": "C4H7O3", "compartment": "e", "id": "3hmp_e", "annotation": {"bigg.metabolite": "3hmp", "sbo": "SBO:0000247", "kegg.compound": "C06001"}}, {"charge": 0, "name": "2-Acetyl-1-alkyl-sn-glycerol", "formula": "C23.0H46.0O4.0", "compartment": "c", "id": "acakg_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C03820"}}, {"charge": 0, "name": "2-Aminomuconate 6-semialdehyde", "formula": "C6H7NO3", "compartment": "c", "id": "am6sa_c", "annotation": {"bigg.metabolite": "am6sa", "sbo": "SBO:0000247", "kegg.compound": "C03824"}}, {"charge": -2, "name": "D-Mannose 1-phosphate", "formula": "C6H11O9P", "compartment": "c", "id": "man1p_c", "annotation": {"bigg.metabolite": "man1p", "sbo": "SBO:0000247", "kegg.compound": "C00636"}}, {"charge": 0, "name": "Indole-3-acetaldehyde", "formula": "C10H9NO", "compartment": "c", "id": "id3acald_c", "annotation": {"bigg.metabolite": "id3acald", "sbo": "SBO:0000247", "kegg.compound": "C00637"}}, {"charge": -3, "name": "D-Glycerate 2-phosphate", "formula": "C3H4O7P", "compartment": "c", "id": "2pg_c", "annotation": {"bigg.metabolite": "2pg", "sbo": "SBO:0000247", "kegg.compound": "C00631"}}, {"charge": 0, "name": "3-Hydroxyanthranilate", "formula": "C7H7NO3", "compartment": "c", "id": "3hanthrn_c", "annotation": {"bigg.metabolite": "3hanthrn", "sbo": "SBO:0000247", "kegg.compound": "C00632"}}, {"charge": -2, "name": "Bilirubin beta-diglucuronide", "formula": "C45H50N4O18", "compartment": "e", "id": "bildglcur_e", "annotation": {"bigg.metabolite": "bildglcur", "sbo": "SBO:0000247", "kegg.compound": "C05787"}}, {"charge": -7, "name": "Lipopolysaccharide (bacteria)", "formula": "C171H297N4O88P2", "compartment": "e", "id": "lps_BAC_e", "annotation": {"bigg.metabolite": "lps_EC", "sbo": "SBO:0000247"}}, {"charge": -2, "name": "Peptidoglycan subunit of bacteria", "formula": "C40H62N8O21", "compartment": "e", "id": "peptido_BAC_e", "annotation": {"bigg.metabolite": ["peptido_EC", "peptido_TB2", "peptido_TB1"], "sbo": "SBO:0000247"}}, {"charge": 0, "name": "L-Proline", "formula": "C5H9NO2", "compartment": "c", "id": "pro-L_c", "annotation": {"bigg.metabolite": "pro-L", "sbo": "SBO:0000247", "kegg.compound": "C00148"}}, {"charge": -2, "name": "L-Malate", "formula": "C4H4O5", "compartment": "c", "id": "mal-L_c", "annotation": {"bigg.metabolite": "mal-L", "sbo": "SBO:0000247", "kegg.compound": "C00149"}}, {"charge": 0, "name": "Protein component of bacterial diet", "formula": "C4.793H7.694N1.3704O1.3964S0.0459", "compartment": "e", "id": "protein_BAC_e", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 0, "name": "Bacteria in diet", "formula": "C39.944Co0.0004Fe0.0011H62.5579Mo0.0063N10.1973O15.2944P0.897S0.2323Se0.0002", "compartment": "e", "id": "BAC_e", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -1, "name": "DNA component of bacterial diet", "formula": "C9.7465H11.2465N3.7535O6.0P1.0", "compartment": "e", "id": "dna_BAC_e", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -1, "name": "RNA component of bacterial diet", "formula": "C9.5853H10.7825N3.9531O6.9499P1.0", "compartment": "e", "id": "rna_BAC_e", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -2, "name": "\"5,10-Methylenetetrahydrofolate\"", "formula": "C20H21N7O6", "compartment": "c", "id": "mlthf_c", "annotation": {"bigg.metabolite": "mlthf", "sbo": "SBO:0000247", "kegg.compound": "C00143"}}, {"charge": 0, "name": "N-Acetyl-D-glucosamine", "formula": "C8H15NO6", "compartment": "c", "id": "acgam_c", "annotation": {"bigg.metabolite": "acgam", "sbo": "SBO:0000247", "kegg.compound": "C00140"}}, {"charge": -1, "name": "3-Methyl-2-oxobutanoate", "formula": "C5H7O3", "compartment": "c", "id": "3mob_c", "annotation": {"bigg.metabolite": "3mob", "sbo": "SBO:0000247", "kegg.compound": "C00141"}}, {"charge": -1, "name": "Phosphatidylglycerol (bacteria)", "formula": "C39.171H74.2872O10.0P1.0", "compartment": "e", "id": "pg_BAC_e", "annotation": {"bigg.metabolite": ["pglyc_hs", "pg190", "pg181", "pg180", "pg161", "pg160190", "pg160", "pg141", "pg140", "pg120", "pg_SA", "pg_EC", "pg_HP", "pg_SC"], "sbo": "SBO:0000247"}}, {"charge": 0, "name": "Phosphatidylethanolamine (bacteria)", "formula": "C38.171H74.2872N1.0O8.0P1.0", "compartment": "e", "id": "pe_BAC_e", "annotation": {"bigg.metabolite": ["pe181", "pe180", "pe161", "pe160", "pe141", "pe140", "pe120", "pe_SA", "pe_hs", "pe_EC", "pe_HP", "pe_SC"], "sbo": "SBO:0000247"}}, {"charge": -2, "name": "GMP", "formula": "C10H12N5O8P", "compartment": "c", "id": "gmp_c", "annotation": {"bigg.metabolite": "gmp", "sbo": "SBO:0000247", "kegg.compound": "C00144"}}, {"charge": 0, "name": "L-Tryptophan", "formula": "C11H12N2O2", "compartment": "m", "id": "trp-L_m", "annotation": {"bigg.metabolite": "trp-L", "sbo": "SBO:0000247", "kegg.compound": "C00078"}}, {"charge": 0, "name": "L-Phenylalanine", "formula": "C9H11NO2", "compartment": "m", "id": "phe-L_m", "annotation": {"bigg.metabolite": "phe-L", "sbo": "SBO:0000247", "kegg.compound": "C00079"}}, {"charge": 0, "name": "Phosphatidylcholine", "formula": "C45.1308H81.1556N1.0O8.0P1.0", "compartment": "e", "id": "pchol_e", "annotation": {"bigg.metabolite": ["pchol_hs", "pc_EC", "pc_SC"], "sbo": "SBO:0000247", "kegg.compound": "C00157"}}, {"charge": -1, "name": "4-Hydroxybenzoate", "formula": "C7H5O3", "compartment": "e", "id": "4hbz_e", "annotation": {"bigg.metabolite": "4hbz", "sbo": "SBO:0000247", "kegg.compound": "C00156"}}, {"charge": 0, "name": "D-Mannose", "formula": "C6H12O6", "compartment": "e", "id": "man_e", "annotation": {"bigg.metabolite": "man", "sbo": "SBO:0000247", "kegg.compound": "C00159"}}, {"charge": 0, "name": "L-Methionine", "formula": "C5H11NO2S", "compartment": "m", "id": "met-L_m", "annotation": {"bigg.metabolite": "met-L", "sbo": "SBO:0000247", "kegg.compound": "C00073"}}, {"charge": -3, "name": "Phosphoenolpyruvate", "formula": "C3H2O6P", "compartment": "m", "id": "pep_m", "annotation": {"bigg.metabolite": "pep", "sbo": "SBO:0000247", "kegg.compound": "C00074"}}, {"charge": 1, "name": "Ornithine", "formula": "C5H13N2O2", "compartment": "m", "id": "orn_m", "annotation": {"bigg.metabolite": "orn", "sbo": "SBO:0000247", "kegg.compound": "C00077"}}, {"charge": 0, "name": "1-Alkenylglycerophosphoethanolamine", "formula": "C23.0H48.0N1.0O6.0P1.0", "compartment": "c", "id": "alken2gpe_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C04635"}}, {"charge": -5, "name": "phosphatidylinositol 4,5-bisphosphate ", "formula": "C46.1308H77.1556O19.0P3.0", "compartment": "c", "id": "pail45p_c", "annotation": {"bigg.metabolite": "pail45p_hs", "sbo": "SBO:0000247", "kegg.compound": "C04637"}}, {"charge": -1, "name": "4-Acetamidobutanoate", "formula": "C6H10NO3", "compartment": "e", "id": "4aabutn_e", "annotation": {"bigg.metabolite": "4aabutn", "sbo": "SBO:0000247", "kegg.compound": "C02946"}}, {"charge": -1, "name": "Pyridoxamine 5'-phosphate", "formula": "C8H12N2O5P", "compartment": "c", "id": "pyam5p_c", "annotation": {"bigg.metabolite": "pyam5p", "sbo": "SBO:0000247", "kegg.compound": "C00647"}}, {"charge": -1, "name": "Superoxide anion", "formula": "O2", "compartment": "c", "id": "o2s_c", "annotation": {"bigg.metabolite": "o2s", "sbo": "SBO:0000247", "kegg.compound": "C00704"}}, {"charge": -3, "name": "dCDP", "formula": "C9H12N3O10P2", "compartment": "c", "id": "dcdp_c", "annotation": {"bigg.metabolite": "dcdp", "sbo": "SBO:0000247", "kegg.compound": "C00705"}}, {"charge": -1, "name": "Iodide", "formula": "I", "compartment": "c", "id": "i_c", "annotation": {"bigg.metabolite": "i", "sbo": "SBO:0000247", "kegg.compound": "C00708"}}, {"charge": 1, "name": "3-Hydroxy-N6,N6,N6-trimethyl-L-lysine", "formula": "C9H21N2O3", "compartment": "m", "id": "3htmelys_m", "annotation": {"bigg.metabolite": "3htmelys", "sbo": "SBO:0000247", "kegg.compound": "C01259"}}, {"charge": 0, "name": "5-Hydroxy-L-tryptophan", "formula": "C11H12N2O3", "compartment": "c", "id": "5htrp_c", "annotation": {"bigg.metabolite": "5htrp", "sbo": "SBO:0000247", "kegg.compound": "C00643"}}, {"charge": -1, "name": "4-Hydroxyphenylacetate", "formula": "C8H7O3", "compartment": "c", "id": "4hphac_c", "annotation": {"bigg.metabolite": "4hphac", "sbo": "SBO:0000247", "kegg.compound": "C00642"}}, {"charge": 0, "name": "1-alkenyl 2-acylglycerol 3-phosphoethanolamine plasmalogen", "formula": "C41.5654H78.5778N1.0O7.0P1.0", "compartment": "c", "id": "alkenac2gpe_c", "annotation": {"bigg.metabolite": "dak2gpe_hs", "sbo": "SBO:0000247", "kegg.compound": "C04756"}}, {"charge": 1, "name": "Sodium", "formula": "Na", "compartment": "e", "id": "na1_e", "annotation": {"bigg.metabolite": "na1", "sbo": "SBO:0000247", "kegg.compound": "C01330"}}, {"charge": -3, "name": "5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate", "formula": "C9H11N3O9P", "compartment": "c", "id": "5aizc_c", "annotation": {"bigg.metabolite": "5aizc", "sbo": "SBO:0000247", "kegg.compound": "C04751"}}, {"charge": -1, "name": "L-erythro-4-Hydroxyglutamate", "formula": "C5H8NO5", "compartment": "m", "id": "e4hglu_m", "annotation": {"bigg.metabolite": "e4hglu", "sbo": "SBO:0000247", "kegg.compound": "C05947"}}, {"charge": -2, "name": "4-Hydroxy-2-oxoglutarate", "formula": "C5H4O6", "compartment": "m", "id": "4h2oglt_m", "annotation": {"bigg.metabolite": "4h2oglt", "sbo": "SBO:0000247", "kegg.compound": "C05946"}}, {"charge": -1, "name": "N-Formylanthranilate", "formula": "C8H6NO3", "compartment": "c", "id": "nformanth_c", "annotation": {"bigg.metabolite": "nformanth", "sbo": "SBO:0000247", "kegg.compound": "C05653"}}, {"charge": -1, "name": "20-Hydroxyeicosatetraenoic acid", "formula": "C20H31O3", "compartment": "c", "id": "20HETE_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C14748"}}, {"charge": -1, "name": "hydroxymethylglutathione", "formula": "C11H18N3O7S", "compartment": "c", "id": "hmgth_c", "annotation": {"bigg.metabolite": "hmgth", "sbo": "SBO:0000247", "kegg.compound": "C14180"}}, {"charge": -2, "name": "ADPribose", "formula": "C15H21N5O14P2", "compartment": "e", "id": "adprib_e", "annotation": {"bigg.metabolite": "adprib", "sbo": "SBO:0000247", "kegg.compound": "C00301"}}, {"charge": 0, "name": "Riboflavin", "formula": "C17H20N4O6", "compartment": "m", "id": "ribflv_m", "annotation": {"bigg.metabolite": "ribflv", "sbo": "SBO:0000247", "kegg.compound": "C00255"}}, {"charge": -1, "name": "D-Lactate", "formula": "C3H5O3", "compartment": "m", "id": "lac-D_m", "annotation": {"bigg.metabolite": "lac-D", "sbo": "SBO:0000247", "kegg.compound": "C00256"}}, {"charge": -2, "name": "L-Glutamate 5-phosphate", "formula": "C5H8NO7P", "compartment": "m", "id": "glu5p_m", "annotation": {"bigg.metabolite": "glu5p", "sbo": "SBO:0000247", "kegg.compound": "C03287"}}, {"charge": 0, "name": "L-3-Amino-isobutanoate", "formula": "C4H9NO2", "compartment": "m", "id": "3aib_m", "annotation": {"bigg.metabolite": "3aib", "sbo": "SBO:0000247", "kegg.compound": "C03284"}}, {"charge": 0, "name": "Limited dextrin 3", "formula": "C6H10O5", "compartment": "c", "id": "dxtrn3_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -2, "name": "poly adp ribose", "formula": "C15H19N5O13P2", "compartment": "c", "id": "polyadprib_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 0, "name": "MM", "formula": "C38.0H64.0N4.0O28.0", "compartment": "c", "id": "m2masn_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 0, "name": "MGnFuc", "formula": "C52.0H87.0N5.0O37.0", "compartment": "c", "id": "fnm2masn_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 0, "name": "MMFuc", "formula": "C44.0H74.0N4.0O32.0", "compartment": "c", "id": "fm2masn_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 0, "name": "non-branching glycogen", "formula": "C6H10O5", "compartment": "c", "id": "nbglycogen_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 0, "name": "Limited dextrin 1", "formula": "C6H10O5", "compartment": "c", "id": "dxtrn1_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 0, "name": "Limited dextrin 2", "formula": "C6H10O5", "compartment": "c", "id": "dxtrn2_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 0, "name": "L-Glutamate 5-semialdehyde", "formula": "C5H9NO3", "compartment": "m", "id": "glu5sa_m", "annotation": {"bigg.metabolite": "glu5sa", "sbo": "SBO:0000247", "kegg.compound": "C01165"}}, {"charge": -4, "name": "\"1D-myo-Inositol 1,4-bisphosphate\"", "formula": "C6H10O12P2", "compartment": "c", "id": "mi14p_c", "annotation": {"bigg.metabolite": "mi14p", "sbo": "SBO:0000247", "kegg.compound": "C01220"}}, {"charge": 0, "name": "Histone N6-acetyl-L-lysine", "formula": "XC8H14N2O2", "compartment": "c", "id": "Naclys_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C01997"}}, {"charge": -1, "name": "3-Hydroxypropanoate", "formula": "C3H5O3", "compartment": "m", "id": "3hpp_m", "annotation": {"bigg.metabolite": "3hpp", "sbo": "SBO:0000247", "kegg.compound": "C01013"}}, {"charge": -4, "name": "Octanoyl-CoA (n-C8:0CoA)", "formula": "C29H46N7O17P3S", "compartment": "c", "id": "occoa_c", "annotation": {"bigg.metabolite": "occoa", "sbo": "SBO:0000247", "kegg.compound": "C01944"}}, {"charge": -4, "name": "26-ascaryl-heptacosanoic acyl coa", "formula": "C54H94N7O21P3S", "compartment": "c", "id": "26ascfa27p0coa_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 0, "name": "4-Hydroxyphenylacetaldehyde", "formula": "C8H8O2", "compartment": "c", "id": "4hoxpacd_c", "annotation": {"bigg.metabolite": "4hoxpacd", "sbo": "SBO:0000247", "kegg.compound": "C03765"}}, {"charge": 0, "name": "tRNA(Sec)", "formula": "ROH", "compartment": "c", "id": "trnasec_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C16636"}}, {"charge": 0, "name": "O-Phosphoseryl-tRNA(Sec)", "formula": "C3H7NO6PR", "compartment": "c", "id": "serptrna_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C16638"}}, {"charge": 0, "name": "Rhodoquinonol-9", "formula": "C53H83NO3", "compartment": "m", "id": "rq9h2_m", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 0, "name": "Glycan pool", "formula": "C13.2771H21.7253N1.2095O9.0201", "compartment": "c", "id": "Glycans_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -1, "name": "R total 6", "formula": "C18.5654H31.5778O2.0", "compartment": "c", "id": "Rtotal6_c", "annotation": {"bigg.metabolite": ["Rtotal", "Rtotal2", "Rtotal3"], "sbo": "SBO:0000247"}}, {"charge": 0, "name": "Body Biomass", "formula": "X", "compartment": "c", "id": "Biomass_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -1, "name": "Vaccenic acid", "formula": "C18H33O2", "compartment": "c", "id": "vacc_c", "annotation": {"bigg.metabolite": "vacc", "sbo": "SBO:0000247"}}, {"charge": 0, "name": "1-hydroxyalkyl-2-lyso-sn-glycero-3-phosphocholine", "formula": "C26.0H56.0N1.0O7.0P1.0", "compartment": "c", "id": "hak2lgchol_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -1, "name": "Leukotriene B4", "formula": "C20H31O4", "compartment": "c", "id": "leuktrB4_c", "annotation": {"bigg.metabolite": "leuktrB4", "sbo": "SBO:0000247", "kegg.compound": "C02165"}}, {"charge": 0, "name": "Deoxyuridine", "formula": "C9H12N2O5", "compartment": "e", "id": "duri_e", "annotation": {"bigg.metabolite": "duri", "sbo": "SBO:0000247", "kegg.compound": "C00526"}}, {"charge": 2, "name": "L-Arginyl-tRNA(Arg)", "formula": "C6H15N4O2R", "compartment": "c", "id": "argtrna_c", "annotation": {"bigg.metabolite": "argtrna", "sbo": "SBO:0000247", "kegg.compound": "C02163"}}, {"charge": 0, "name": "Rhodoquinone-9", "formula": "C53H81NO3", "compartment": "m", "id": "rq9_m", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -2, "name": "beta-D-Mannosyldiacetylchitobiosyldiphosphodolichol", "formula": "C132H216N2O22P2", "compartment": "c", "id": "mpdol_c", "annotation": {"bigg.metabolite": ["macchitppdol", "mpdol_L", "mpdol_U"], "sbo": "SBO:0000247", "kegg.compound": "C05860"}}, {"charge": -2, "name": "alpha-D-mannosyl-beta-D-mannosyl-diacylchitobiosyldiphosphodolichol", "formula": "C138H226N2O27P2", "compartment": "c", "id": "m1mpdol_c", "annotation": {"bigg.metabolite": ["m1macchitppdol", "m1mpdol_L", "m1mpdol_U"], "sbo": "SBO:0000247", "kegg.compound": "C05861"}}, {"charge": -3, "name": "D-4'-Phosphopantothenate", "formula": "C9H15NO8P", "compartment": "c", "id": "4ppan_c", "annotation": {"bigg.metabolite": "4ppan", "sbo": "SBO:0000247", "kegg.compound": "C03492"}}, {"charge": 0, "name": "Glycine betaine", "formula": "C5H11NO2", "compartment": "m", "id": "glyb_m", "annotation": {"bigg.metabolite": "glyb", "sbo": "SBO:0000247", "kegg.compound": "C00719"}}, {"charge": 0, "name": "3-Hydroxyanthranilate", "formula": "C7H7NO3", "compartment": "e", "id": "3hanthrn_e", "annotation": {"bigg.metabolite": "3hanthrn", "sbo": "SBO:0000247", "kegg.compound": "C00632"}}, {"charge": 1, "name": "H+", "formula": "H", "compartment": "m", "id": "h_m", "annotation": {"bigg.metabolite": "h", "sbo": "SBO:0000247", "kegg.compound": "C00080"}}, {"charge": 1, "name": "L-Prolyl-tRNA(Pro)", "formula": "C5H9NO2R", "compartment": "c", "id": "protrna_c", "annotation": {"bigg.metabolite": "protrna", "sbo": "SBO:0000247", "kegg.compound": "C02702"}}, {"charge": 0, "name": "L-Formylkynurenine", "formula": "C11H12N2O4", "compartment": "c", "id": "Lfmkynr_c", "annotation": {"bigg.metabolite": "Lfmkynr", "sbo": "SBO:0000247", "kegg.compound": "C02700"}}, {"charge": -3, "name": "N-((R)-4-Phosphopantothenoyl)-L-cysteine", "formula": "C12H20N2O9PS", "compartment": "c", "id": "4ppcys_c", "annotation": {"bigg.metabolite": "4ppcys", "sbo": "SBO:0000247", "kegg.compound": "C04352"}}, {"charge": -1, "name": "Leukotriene B4", "formula": "C20H31O4", "compartment": "e", "id": "leuktrB4_e", "annotation": {"bigg.metabolite": "leuktrB4", "sbo": "SBO:0000247", "kegg.compound": "C02165"}}, {"charge": -1, "name": "4-Acetamidobutanoate", "formula": "C6H10NO3", "compartment": "c", "id": "4aabutn_c", "annotation": {"bigg.metabolite": "4aabutn", "sbo": "SBO:0000247", "kegg.compound": "C02946"}}, {"charge": -4, "name": "4-hydroxybenoyl-CoA", "formula": "C28H36N7O18P3S", "compartment": "c", "id": "4hbzcoa_c", "annotation": {"bigg.metabolite": "4hbzcoa", "sbo": "SBO:0000247", "kegg.compound": "C02949"}}, {"charge": -4, "name": "C20:4-CoA", "formula": "C41H62N7O17P3S", "compartment": "m", "id": "arachdcoa_m", "annotation": {"bigg.metabolite": "arachdcoa", "sbo": "SBO:0000247", "kegg.compound": "C02249"}}, {"charge": 0, "name": "Apo cytochrome C", "formula": "C8H12N4O4S2R4", "compartment": "m", "id": "apocytc_m", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C02248"}}, {"charge": -2, "name": "1D-myo-Inositol 4-phosphate", "formula": "C6H11O9P", "compartment": "c", "id": "mi4p-D_c", "annotation": {"bigg.metabolite": "mi4p-D", "sbo": "SBO:0000247", "kegg.compound": "C03546"}}, {"charge": -1, "name": "1-Pyrroline-5-carboxylate", "formula": "C5H6NO2", "compartment": "m", "id": "1pyr5c_m", "annotation": {"bigg.metabolite": "1pyr5c", "sbo": "SBO:0000247", "kegg.compound": "C03912"}}, {"charge": -4, "name": "\"Sedoheptulose 1,7-bisphosphate\"", "formula": "C7H12O13P2", "compartment": "c", "id": "s17bp_c", "annotation": {"bigg.metabolite": "s17bp", "sbo": "SBO:0000247", "kegg.compound": "C00447"}}, {"charge": -2, "name": "alpha-D-Galactose 1-phosphate", "formula": "C6H11O9P", "compartment": "c", "id": "gal1p_c", "annotation": {"bigg.metabolite": "gal1p", "sbo": "SBO:0000247", "kegg.compound": "C00446"}}, {"charge": -1, "name": "\"5,10-Methenyltetrahydrofolate\"", "formula": "C20H20N7O6", "compartment": "c", "id": "methf_c", "annotation": {"bigg.metabolite": "methf", "sbo": "SBO:0000247", "kegg.compound": "C00445"}}, {"charge": -1, "name": "5-Methyltetrahydrofolate", "formula": "C20H24N7O6", "compartment": "c", "id": "5mthf_c", "annotation": {"bigg.metabolite": "5mthf", "sbo": "SBO:0000247", "kegg.compound": "C00440"}}, {"charge": -2, "name": "Adenylated molybdopterin", "formula": "C10H10N5O8PS2Mo", "compartment": "c", "id": "moco_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C18237"}}, {"charge": -3, "name": "Farnesyl diphosphate", "formula": "C15H25O7P2", "compartment": "c", "id": "frdp_c", "annotation": {"bigg.metabolite": "frdp", "sbo": "SBO:0000247", "kegg.compound": "C00448"}}, {"charge": -1, "name": "alpha-Ketoglutaramate", "formula": "C5H6NO4", "compartment": "e", "id": "akgm_e", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C00940"}}, {"charge": -1, "name": "\"3',5'-Cyclic GMP\"", "formula": "C10H11N5O7P", "compartment": "e", "id": "35cgmp_e", "annotation": {"bigg.metabolite": "35cgmp", "sbo": "SBO:0000247", "kegg.compound": "C00942"}}, {"charge": -2, "name": "Glycerol 3-phosphate", "formula": "C3H7O6P", "compartment": "e", "id": "glyc3p_e", "annotation": {"bigg.metabolite": "glyc3p", "sbo": "SBO:0000247", "kegg.compound": "C00093"}}, {"charge": 0, "name": "L-Cysteine", "formula": "C3H7NO2S", "compartment": "e", "id": "cys-L_e", "annotation": {"bigg.metabolite": "cys-L", "sbo": "SBO:0000247", "kegg.compound": "C00097"}}, {"charge": -2, "name": "Sulfite", "formula": "O3S", "compartment": "e", "id": "so3_e", "annotation": {"bigg.metabolite": "so3", "sbo": "SBO:0000247", "kegg.compound": "C00094"}}, {"charge": 0, "name": "D-Fructose", "formula": "C6H12O6", "compartment": "e", "id": "fru_e", "annotation": {"bigg.metabolite": "fru", "sbo": "SBO:0000247", "kegg.compound": "C00095"}}, {"charge": 0, "name": "beta-Alanine", "formula": "C3H7NO2", "compartment": "e", "id": "ala-B_e", "annotation": {"bigg.metabolite": "ala-B", "sbo": "SBO:0000247", "kegg.compound": "C00099"}}, {"charge": -1, "name": "N1-(5-Phospho-D-ribosyl)glycinamide", "formula": "C7H14N2O8P", "compartment": "c", "id": "gar_c", "annotation": {"bigg.metabolite": "gar", "sbo": "SBO:0000247", "kegg.compound": "C03838"}}, {"charge": 0, "name": "Melibiose", "formula": "C12H22O11", "compartment": "c", "id": "melib_c", "annotation": {"bigg.metabolite": "melib", "sbo": "SBO:0000247", "kegg.compound": "C05402"}}, {"charge": -1, "name": "1-Acyl-sn-glycero-3-phosphoserine", "formula": "C24.5654H43.5778N1.0O9.0P1.0", "compartment": "c", "id": "acg3ps_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C18125"}}, {"charge": -3, "name": "Dolichol diphosphate", "formula": "C110H179O7P2", "compartment": "c", "id": "doldp_c", "annotation": {"bigg.metabolite": "doldp", "sbo": "SBO:0000247", "kegg.compound": "C00621"}}, {"charge": -1, "name": "1-Acyl-sn-glycero-3-phosphoglycerol", "formula": "C24.5654H44.5778O9.0P1.0", "compartment": "c", "id": "lpglyc_c", "annotation": {"bigg.metabolite": ["2agpg181", "2agpg180", "2agpg161", "2agpg160", "2agpg141", "2agpg140", "2agpg120", "1agpg181", "1agpg180", "1agpg161", "1agpg160", "1agpg141", "1agpg140", "1agpg120", "agpg_EC", "1glyc_hs"], "sbo": "SBO:0000247", "kegg.compound": "C18126"}}, {"charge": -2, "name": "Pyridoxine 5'-phosphate", "formula": "C8H10NO6P", "compartment": "c", "id": "pdx5p_c", "annotation": {"bigg.metabolite": "pdx5p", "sbo": "SBO:0000247", "kegg.compound": "C00627"}}, {"charge": -1, "name": "Sphinganine 1-phosphate", "formula": "C19H41NO5P", "compartment": "e", "id": "sph1p_ce_e", "annotation": {"bigg.metabolite": "sph1p", "sbo": "SBO:0000247"}}, {"charge": 0, "name": "Sphingomyelin", "formula": "C42.5654H81.5778N2.0O6.0P1.0", "compartment": "e", "id": "sphmyln_ce_e", "annotation": {"bigg.metabolite": "sphmyln_hs", "sbo": "SBO:0000247"}}, {"charge": -2, "name": "Ceramide 1-phosphate", "formula": "C37.5654H68.5778N1.0O6.0P1.0", "compartment": "e", "id": "crmp_ce_e", "annotation": {"bigg.metabolite": "crmp_hs", "sbo": "SBO:0000247"}}, {"charge": 1, "name": "sphingosylphosphorylcholine ", "formula": "C24H52N2O5P", "compartment": "e", "id": "spc_ce_e", "annotation": {"bigg.metabolite": "spc_hs", "sbo": "SBO:0000247"}}, {"charge": 1, "name": "Sphinganine", "formula": "C19H42NO2", "compartment": "e", "id": "sphgn_ce_e", "annotation": {"bigg.metabolite": "sphgn", "sbo": "SBO:0000247"}}, {"charge": -1, "name": "Phosphatidylserine (bacteria)", "formula": "C39.171H73.2872N1.0O10.0P1.0", "compartment": "e", "id": "ps_BAC_e", "annotation": {"bigg.metabolite": ["ps181", "ps180", "ps161", "ps160", "ps141", "ps140", "ps120", "ps_SA", "ps_hs", "ps_EC", "ps_HP", "ps_SC"], "sbo": "SBO:0000247"}}, {"charge": -3, "name": "Citrate", "formula": "C6H5O7", "compartment": "c", "id": "cit_c", "annotation": {"bigg.metabolite": "cit", "sbo": "SBO:0000247", "kegg.compound": "C00158"}}, {"charge": 0, "name": "L-Serine", "formula": "C3H7NO3", "compartment": "m", "id": "ser-L_m", "annotation": {"bigg.metabolite": "ser-L", "sbo": "SBO:0000247", "kegg.compound": "C00065"}}, {"charge": -2, "name": "Cardiolipin (bacteria)", "formula": "C75.342H140.5744O17.0P2.0", "compartment": "e", "id": "clpn_BAC_e", "annotation": {"bigg.metabolite": ["clpn181", "clpn180", "clpn161", "clpn160190", "clpn160", "clpn141", "clpn140", "clpn120", "clpn_SA", "clpn_hs", "clpn_HP", "clpn_EC"], "sbo": "SBO:0000247"}}, {"charge": 1, "name": "L-Arginine", "formula": "C6H15N4O2", "compartment": "m", "id": "arg-L_m", "annotation": {"bigg.metabolite": "arg-L", "sbo": "SBO:0000247", "kegg.compound": "C00062"}}, {"charge": -2, "name": "FMN", "formula": "C17H19N4O9P", "compartment": "m", "id": "fmn_m", "annotation": {"bigg.metabolite": "fmn", "sbo": "SBO:0000247", "kegg.compound": "C00061"}}, {"charge": 0, "name": "Nicotinamide", "formula": "C6H6N2O", "compartment": "c", "id": "ncam_c", "annotation": {"bigg.metabolite": "ncam", "sbo": "SBO:0000247", "kegg.compound": "C00153"}}, {"charge": 0, "name": "L-Asparagine", "formula": "C4H8N2O3", "compartment": "c", "id": "asn-L_c", "annotation": {"bigg.metabolite": "asn-L", "sbo": "SBO:0000247", "kegg.compound": "C00152"}}, {"charge": 0, "name": "L-Homocysteine", "formula": "C4H9NO2S", "compartment": "c", "id": "hcys-L_c", "annotation": {"bigg.metabolite": "hcys-L", "sbo": "SBO:0000247", "kegg.compound": "C00155"}}, {"charge": -4, "name": "Palmitoyl-CoA (n-C16:0CoA)", "formula": "C37H62N7O17P3S", "compartment": "c", "id": "pmtcoa_c", "annotation": {"bigg.metabolite": "pmtcoa", "sbo": "SBO:0000247", "kegg.compound": "C00154"}}, {"charge": 0, "name": "Phosphatidylcholine", "formula": "C45.1308H81.1556N1.0O8.0P1.0", "compartment": "c", "id": "pchol_c", "annotation": {"bigg.metabolite": ["pchol_hs", "pc_EC", "pc_SC"], "sbo": "SBO:0000247", "kegg.compound": "C00157"}}, {"charge": -2, "name": "Thiamine diphosphate", "formula": "C12H16N4O7P2S", "compartment": "m", "id": "thmpp_m", "annotation": {"bigg.metabolite": "thmpp", "sbo": "SBO:0000247", "kegg.compound": "C00068"}}, {"charge": 1, "name": "alpha-Aminopropiononitrile", "formula": "C3H7N2", "compartment": "c", "id": "aprop_c", "annotation": {"bigg.metabolite": "aprop", "sbo": "SBO:0000247", "kegg.compound": "C05714"}}, {"charge": -1, "name": "3-(4-Hydroxyphenyl)lactate", "formula": "C9H9O4", "compartment": "m", "id": "34hpl_m", "annotation": {"bigg.metabolite": "34hpl", "sbo": "SBO:0000247", "kegg.compound": "C03672"}}, {"charge": 0, "name": "glycocholate", "formula": "C26H43NO6", "compartment": "e", "id": "gchola_e", "annotation": {"bigg.metabolite": "gchola", "sbo": "SBO:0000247", "kegg.compound": "C01921"}}, {"charge": -2, "name": "Selenite", "formula": "O3Se", "compartment": "e", "id": "selnt_e", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C05684"}}, {"charge": 0, "name": "Selenocysteine", "formula": "C3H7NO2Se", "compartment": "e", "id": "selcys_e", "annotation": {"bigg.metabolite": "selcys", "sbo": "SBO:0000247", "kegg.compound": "C05688"}}, {"charge": 0, "name": "\"3,5-Diiodo-L-tyrosine\"", "formula": "C9H9I2NO3", "compartment": "c", "id": "35diotyr_c", "annotation": {"bigg.metabolite": "35diotyr", "sbo": "SBO:0000247", "kegg.compound": "C01060"}}, {"charge": 0, "name": "Deoxyguanosine", "formula": "C10H13N5O4", "compartment": "m", "id": "dgsn_m", "annotation": {"bigg.metabolite": "dgsn", "sbo": "SBO:0000247", "kegg.compound": "C00330"}}, {"charge": 0, "name": "Glycine betaine", "formula": "C5H11NO2", "compartment": "c", "id": "glyb_c", "annotation": {"bigg.metabolite": "glyb", "sbo": "SBO:0000247", "kegg.compound": "C00719"}}, {"charge": 0, "name": "Ubiquinol", "formula": "C14H20O4", "compartment": "m", "id": "qh2_m", "annotation": {"bigg.metabolite": "qh2", "sbo": "SBO:0000247", "kegg.compound": "C00390"}}, {"charge": 0, "name": "Ubiquinone", "formula": "C14H18O4", "compartment": "m", "id": "q_m", "annotation": {"bigg.metabolite": "q", "sbo": "SBO:0000247", "kegg.compound": "C00399"}}, {"charge": -1, "name": "\"3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoate\"", "formula": "C27H45O5", "compartment": "c", "id": "thcholstoic_c", "annotation": {"bigg.metabolite": "thcholstoic", "sbo": "SBO:0000247", "kegg.compound": "C04722"}}, {"charge": 0, "name": "Hydrogen cyanide", "formula": "CHN", "compartment": "e", "id": "cyan_e", "annotation": {"bigg.metabolite": "cyan", "sbo": "SBO:0000247", "kegg.compound": "C01326"}}, {"charge": -1, "name": "hydroxide ion", "formula": "HO", "compartment": "e", "id": "oh1_e", "annotation": {"bigg.metabolite": "oh1", "sbo": "SBO:0000247", "kegg.compound": "C01328"}}, {"charge": -1, "name": "cAMP", "formula": "C10H11N5O6P", "compartment": "e", "id": "camp_e", "annotation": {"bigg.metabolite": "camp", "sbo": "SBO:0000247", "kegg.compound": "C00575"}}, {"charge": -1, "name": "11,12-DHET", "formula": "C20H33O4", "compartment": "c", "id": "dhet_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C14774"}}, {"charge": -1, "name": "\"5-Hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoate\"", "formula": "C20H31O4", "compartment": "e", "id": "5HPET_e", "annotation": {"bigg.metabolite": "5HPET", "sbo": "SBO:0000247", "kegg.compound": "C05356"}}, {"charge": -2, "name": "(alpha-D-Mannosyl)4-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol", "formula": "C156H256N2O42P2", "compartment": "c", "id": "m4mpdol_c", "annotation": {"bigg.metabolite": ["m4macchitppdol", "m4mpdol_L", "m4mpdol_U"], "sbo": "SBO:0000247"}}, {"charge": -3, "name": "Isocitrate", "formula": "C6H5O7", "compartment": "e", "id": "icit_e", "annotation": {"bigg.metabolite": "icit", "sbo": "SBO:0000247", "kegg.compound": "C00311"}}, {"charge": -1, "name": "Phosphatidylserine (bacteria)", "formula": "C39.171H73.2872N1.0O10.0P1.0", "compartment": "m", "id": "ps_BAC_m", "annotation": {"bigg.metabolite": ["ps181", "ps180", "ps161", "ps160", "ps141", "ps140", "ps120", "ps_SA", "ps_hs", "ps_EC", "ps_HP", "ps_SC"], "sbo": "SBO:0000247"}}, {"charge": 3, "name": "Spermidine", "formula": "C7H22N3", "compartment": "e", "id": "spmd_e", "annotation": {"bigg.metabolite": "spmd", "sbo": "SBO:0000247", "kegg.compound": "C00315"}}, {"charge": 0, "name": "Pyridoxine", "formula": "C8H11NO3", "compartment": "e", "id": "pydxn_e", "annotation": {"bigg.metabolite": "pydxn", "sbo": "SBO:0000247", "kegg.compound": "C00314"}}, {"charge": -2, "name": "(alpha-D-Glucosyl)2-(alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol", "formula": "C192H316N2O72P2", "compartment": "c", "id": "g2m8mpdol_c", "annotation": {"bigg.metabolite": ["g2m8mpdol_L", "g2m8mpdol_U"], "sbo": "SBO:0000247"}}, {"charge": 0, "name": "dodecanoyl carnitine", "formula": "C19H37NO4", "compartment": "m", "id": "ddcrn_m", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -1, "name": "Outer section of lipopolysaccharide (bacteria)", "formula": "C61H101N2O49", "compartment": "c", "id": "outerlps_BAC_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -6, "name": "KDO(2)-lipid (A)", "formula": "C110H196N2O39P2", "compartment": "c", "id": "lipa_BAC_c", "annotation": {"bigg.metabolite": "lipa", "sbo": "SBO:0000247"}}, {"charge": -2, "name": "Peptidoglycan subunit of bacteria", "formula": "C40H62N8O21", "compartment": "c", "id": "peptido_BAC_c", "annotation": {"bigg.metabolite": ["peptido_EC", "peptido_TB2", "peptido_TB1"], "sbo": "SBO:0000247"}}, {"charge": -1, "name": "DNA component of bacterial diet", "formula": "C9.7465H11.2465N3.7535O6.0P1.0", "compartment": "c", "id": "dna_BAC_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -1, "name": "RNA component of bacterial diet", "formula": "C9.5853H10.7825N3.9531O6.9499P1.0", "compartment": "c", "id": "rna_BAC_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 0, "name": "Protein component of bacterial diet", "formula": "C4.793H7.694N1.3704O1.3964S0.0459", "compartment": "c", "id": "protein_BAC_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 0, "name": "trans-4-Hydroxy-L-proline", "formula": "C5H9NO3", "compartment": "c", "id": "4hpro-LT_c", "annotation": {"bigg.metabolite": "4hpro-LT", "sbo": "SBO:0000247", "kegg.compound": "C01157"}}, {"charge": 0, "name": "Guanine", "formula": "C5H5N5O", "compartment": "m", "id": "gua_m", "annotation": {"bigg.metabolite": "gua", "sbo": "SBO:0000247", "kegg.compound": "C00242"}}, {"charge": 1, "name": "Procollagen 5-hydroxy-L-lysine", "formula": "XHO", "compartment": "e", "id": "pcollg5hlys_e", "annotation": {"bigg.metabolite": "pcollg5hlys", "sbo": "SBO:0000247", "kegg.compound": "C01211"}}, {"charge": 0, "name": "Phosphatidylethanolamine (bacteria)", "formula": "C38.171H74.2872N1.0O8.0P1.0", "compartment": "c", "id": "pe_BAC_c", "annotation": {"bigg.metabolite": ["pe181", "pe180", "pe161", "pe160", "pe141", "pe140", "pe120", "pe_SA", "pe_hs", "pe_EC", "pe_HP", "pe_SC"], "sbo": "SBO:0000247"}}, {"charge": -1, "name": "4-Methyl-2-oxopentanoate", "formula": "C6H9O3", "compartment": "m", "id": "4mop_m", "annotation": {"bigg.metabolite": "4mop", "sbo": "SBO:0000247", "kegg.compound": "C00233"}}, {"charge": 0, "name": "N-Acetyl-D-galactosamine", "formula": "C8H15NO6", "compartment": "e", "id": "acgal_e", "annotation": {"bigg.metabolite": "acgal", "sbo": "SBO:0000247", "kegg.compound": "C01132"}}, {"charge": -4, "name": "(R)-5-Diphosphomevalonate", "formula": "C6H10O10P2", "compartment": "c", "id": "5dpmev_c", "annotation": {"bigg.metabolite": "5dpmev", "sbo": "SBO:0000247", "kegg.compound": "C01143"}}, {"charge": -4, "name": "3-Oxohexadecanoyl-CoA", "formula": "C37H60N7O18P3S", "compartment": "c", "id": "3ohdcoa_c", "annotation": {"bigg.metabolite": "3ohdcoa", "sbo": "SBO:0000247", "kegg.compound": "C05259"}}, {"charge": 1, "name": "N-Methylhistamine", "formula": "C6H12N3", "compartment": "e", "id": "mhista_e", "annotation": {"bigg.metabolite": "mhista", "sbo": "SBO:0000247", "kegg.compound": "C05127"}}, {"charge": -1, "name": "D-Aspartate", "formula": "C4H6NO4", "compartment": "e", "id": "asp-D_e", "annotation": {"bigg.metabolite": "asp-D", "sbo": "SBO:0000247", "kegg.compound": "C00402"}}, {"charge": 0, "name": "\"3alpha,7alpha,12alpha,26-Tetrahydroxy-5beta-cholestane\"", "formula": "C27H48O4", "compartment": "m", "id": "xoltetrol_m", "annotation": {"bigg.metabolite": "xoltetrol", "sbo": "SBO:0000247", "kegg.compound": "C05446"}}, {"charge": -1, "name": "4-Hydroxy-2-quinolinecarboxylic acid", "formula": "C10H6NO3", "compartment": "c", "id": "kynate_c", "annotation": {"bigg.metabolite": "kynate", "sbo": "SBO:0000247", "kegg.compound": "C01717"}}, {"charge": -4, "name": "(S)-3-Hydroxyoctanoyl-CoA", "formula": "C29H46N7O18P3S", "compartment": "m", "id": "3hocoa_m", "annotation": {"bigg.metabolite": "3hocoa", "sbo": "SBO:0000247", "kegg.compound": "C05266"}}, {"charge": -4, "name": "3-Oxooctanoyl-CoA", "formula": "C29H44N7O18P3S", "compartment": "m", "id": "3oocoa_m", "annotation": {"bigg.metabolite": "3oocoa", "sbo": "SBO:0000247", "kegg.compound": "C05267"}}, {"charge": -4, "name": "(S)-3-Hydroxydecanoyl-CoA", "formula": "C31H50N7O18P3S", "compartment": "m", "id": "3hdcoa_m", "annotation": {"bigg.metabolite": "3hdcoa", "sbo": "SBO:0000247", "kegg.compound": "C05264"}}, {"charge": -4, "name": "3-Oxodecanoyl-CoA", "formula": "C31H48N7O18P3S", "compartment": "m", "id": "3odcoa_m", "annotation": {"bigg.metabolite": "3odcoa", "sbo": "SBO:0000247", "kegg.compound": "C05265"}}, {"charge": -4, "name": "(S)-3-Hydroxydodecanoyl-CoA", "formula": "C33H54N7O18P3S", "compartment": "m", "id": "3hddcoa_m", "annotation": {"bigg.metabolite": "3hddcoa", "sbo": "SBO:0000247", "kegg.compound": "C05262"}}, {"charge": -4, "name": "3-Oxododecanoyl-CoA", "formula": "C33H52N7O18P3S", "compartment": "m", "id": "3oddcoa_m", "annotation": {"bigg.metabolite": "3oddcoa", "sbo": "SBO:0000247", "kegg.compound": "C05263"}}, {"charge": -4, "name": "(S)-3-Hydroxytetradecanoyl-CoA", "formula": "C35H58N7O18P3S", "compartment": "m", "id": "3htdcoa_m", "annotation": {"bigg.metabolite": "3htdcoa", "sbo": "SBO:0000247", "kegg.compound": "C05260"}}, {"charge": -4, "name": "3-Oxotetradecanoyl-CoA", "formula": "C35H56N7O18P3S", "compartment": "m", "id": "3otdcoa_m", "annotation": {"bigg.metabolite": "3otdcoa", "sbo": "SBO:0000247", "kegg.compound": "C05261"}}, {"charge": -4, "name": "(S)-3-Hydroxyhexanoyl-CoA", "formula": "C27H42N7O18P3S", "compartment": "m", "id": "3hhcoa_m", "annotation": {"bigg.metabolite": "3hhcoa", "sbo": "SBO:0000247", "kegg.compound": "C05268"}}, {"charge": -4, "name": "3-Oxohexanoyl-CoA", "formula": "C27H40N7O18P3S", "compartment": "m", "id": "3ohcoa_m", "annotation": {"bigg.metabolite": "3ohcoa", "sbo": "SBO:0000247", "kegg.compound": "C05269"}}, {"charge": -2, "name": "Alkyl-glycerone 3-phosphate", "formula": "C21.0H41.0O6.0P1.0", "compartment": "c", "id": "akdhap_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C03715"}}, {"charge": 0, "name": "Peptide diphthine", "formula": "C14H21N5O4R2", "compartment": "c", "id": "pdipht_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C01573"}}, {"charge": -1, "name": "Thiocyanate", "formula": "CNS", "compartment": "m", "id": "tcynt_m", "annotation": {"bigg.metabolite": "tcynt", "sbo": "SBO:0000247", "kegg.compound": "C01755"}}, {"charge": -4, "name": "3-Hydroxypropionyl-CoA", "formula": "C24H36N7O18P3S", "compartment": "m", "id": "3hpcoa_m", "annotation": {"bigg.metabolite": "3hpcoa", "sbo": "SBO:0000247", "kegg.compound": "C05668"}}, {"charge": 0, "name": "Phospholipids", "formula": "C43.4949H79.2379N1.0482O7.8601P1.0157", "compartment": "c", "id": "PhosphoL_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -4, "name": "R total 6 Coenzyme A", "formula": "C39.5654H62.5778N7.0O17.0P3.0S1.0", "compartment": "c", "id": "Rtotal6coa_c", "annotation": {"bigg.metabolite": ["Rtotalcoa", "Rtotal2coa", "Rtotal3coa", "acoa"], "sbo": "SBO:0000247"}}, {"charge": -2, "name": "Sedoheptulose 7-phosphate", "formula": "C7H13O10P", "compartment": "c", "id": "s7p_c", "annotation": {"bigg.metabolite": "s7p", "sbo": "SBO:0000247", "kegg.compound": "C05382"}}, {"charge": -1, "name": "DNA (biomass)", "formula": "C9.825H11.325N3.675O6.0P1.0", "compartment": "c", "id": "DNA_c", "annotation": {"bigg.metabolite": "DNA", "sbo": "SBO:0000247"}}, {"charge": -1, "name": "RNA (biomass)", "formula": "C9.467H10.6954N3.6294O7.0711P1.0", "compartment": "c", "id": "RNA_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 0, "name": "tRNA(Ala)", "formula": "ROH", "compartment": "m", "id": "trnaala_m", "annotation": {"bigg.metabolite": "trnaala", "sbo": "SBO:0000247", "kegg.compound": "C01635"}}, {"charge": 0, "name": "tRNA(Asn)", "formula": "ROH", "compartment": "m", "id": "trnaasn_m", "annotation": {"bigg.metabolite": "trnaasn", "sbo": "SBO:0000247", "kegg.compound": "C01637"}}, {"charge": 0, "name": "tRNA(Arg)", "formula": "ROH", "compartment": "m", "id": "trnaarg_m", "annotation": {"bigg.metabolite": "trnaarg", "sbo": "SBO:0000247", "kegg.compound": "C01636"}}, {"charge": 0, "name": "tRNA(Cys)", "formula": "ROH", "compartment": "m", "id": "trnacys_m", "annotation": {"bigg.metabolite": "trnacys", "sbo": "SBO:0000247", "kegg.compound": "C01639"}}, {"charge": 0, "name": "tRNA(Asp)", "formula": "ROH", "compartment": "m", "id": "trnaasp_m", "annotation": {"bigg.metabolite": "trnaasp", "sbo": "SBO:0000247", "kegg.compound": "C01638"}}, {"charge": -4, "name": "dGTP", "formula": "C10H12N5O13P3", "compartment": "m", "id": "dgtp_m", "annotation": {"bigg.metabolite": "dgtp", "sbo": "SBO:0000247", "kegg.compound": "C00286"}}, {"charge": -3, "name": "D-Glycerate 2-phosphate", "formula": "C3H4O7P", "compartment": "e", "id": "2pg_e", "annotation": {"bigg.metabolite": "2pg", "sbo": "SBO:0000247", "kegg.compound": "C00631"}}, {"charge": 1, "name": "N-Ribosylnicotinamide", "formula": "C11H15N2O5", "compartment": "c", "id": "rnam_c", "annotation": {"bigg.metabolite": "rnam", "sbo": "SBO:0000247", "kegg.compound": "C03150"}}, {"charge": -1, "name": "linoleic acid (all cis C18:2) n-6", "formula": "C18H31O2", "compartment": "e", "id": "lnlc_e", "annotation": {"bigg.metabolite": "lnlc", "sbo": "SBO:0000247", "kegg.compound": "C01595"}}, {"charge": 1, "name": "N-Acetylputrescine", "formula": "C6H15N2O", "compartment": "c", "id": "aprut_c", "annotation": {"bigg.metabolite": "aprut", "sbo": "SBO:0000247", "kegg.compound": "C02714"}}, {"charge": -4, "name": "Dodecanoyl-CoA (n-C12:0CoA)", "formula": "C33H54N7O17P3S", "compartment": "m", "id": "ddcacoa_m", "annotation": {"bigg.metabolite": "ddcacoa", "sbo": "SBO:0000247", "kegg.compound": "C01832"}}, {"charge": 0, "name": "protein-linked asparagine residue (N-glycosylation site)", "formula": "C4.0H8.0N2.0O3.0", "compartment": "c", "id": "Asn-X-Ser/Thr_c", "annotation": {"bigg.metabolite": "Asn-X-Ser/Thr", "sbo": "SBO:0000247", "kegg.compound": "C03021"}}, {"charge": -1, "name": "(S)-3-Hydroxybutanoate", "formula": "C4H7O3", "compartment": "e", "id": "S3hb_e", "annotation": {"bigg.metabolite": "bhb", "sbo": "SBO:0000247", "kegg.compound": "C03197"}}, {"charge": -2, "name": "3-Sulfinopyruvate", "formula": "C3H2O5S", "compartment": "c", "id": "3snpyr_c", "annotation": {"bigg.metabolite": "3snpyr", "sbo": "SBO:0000247", "kegg.compound": "C05527"}}, {"charge": -1, "name": "Outer section of lipopolysaccharide (bacteria)", "formula": "C61H101N2O49", "compartment": "e", "id": "outerlps_BAC_e", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -1, "name": "\"3',5'-Cyclic GMP\"", "formula": "C10H11N5O7P", "compartment": "c", "id": "35cgmp_c", "annotation": {"bigg.metabolite": "35cgmp", "sbo": "SBO:0000247", "kegg.compound": "C00942"}}, {"charge": -1, "name": "alpha-Ketoglutaramate", "formula": "C5H6NO4", "compartment": "c", "id": "akgm_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C00940"}}, {"charge": -6, "name": "KDO(2)-lipid (A)", "formula": "C110H196N2O39P2", "compartment": "e", "id": "lipa_BAC_e", "annotation": {"bigg.metabolite": "lipa", "sbo": "SBO:0000247"}}, {"charge": 1, "name": "Dopamine", "formula": "C8H12NO2", "compartment": "e", "id": "dopa_e", "annotation": {"bigg.metabolite": "dopa", "sbo": "SBO:0000247", "kegg.compound": "C03758"}}, {"charge": 0, "name": "N2-Acetyl-L-ornithine", "formula": "C7H14N2O3", "compartment": "c", "id": "acorn_c", "annotation": {"bigg.metabolite": "acorn", "sbo": "SBO:0000247", "kegg.compound": "C00437"}}, {"charge": -2, "name": "N-Carbamoyl-L-aspartate", "formula": "C5H6N2O5", "compartment": "c", "id": "cbasp_c", "annotation": {"bigg.metabolite": "cbasp", "sbo": "SBO:0000247", "kegg.compound": "C00438"}}, {"charge": -2, "name": "N-Formimidoyl-L-glutamate", "formula": "C6H8N2O4", "compartment": "c", "id": "forglu_c", "annotation": {"bigg.metabolite": "forglu", "sbo": "SBO:0000247", "kegg.compound": "C00439"}}, {"charge": -1, "name": "L-2-Aminoadipate", "formula": "C6H10NO4", "compartment": "e", "id": "L2aadp_e", "annotation": {"bigg.metabolite": "L2aadp", "sbo": "SBO:0000247", "kegg.compound": "C00956"}}, {"charge": -1, "name": "Indole-3-acetate", "formula": "C10H8NO2", "compartment": "e", "id": "ind3ac_e", "annotation": {"bigg.metabolite": "ind3ac", "sbo": "SBO:0000247", "kegg.compound": "C00954"}}, {"charge": -4, "name": "ITP", "formula": "C10H11N4O14P3", "compartment": "e", "id": "itp_e", "annotation": {"bigg.metabolite": "itp", "sbo": "SBO:0000247", "kegg.compound": "C00081"}}, {"charge": 1, "name": "H+", "formula": "H", "compartment": "e", "id": "h_e", "annotation": {"bigg.metabolite": "h", "sbo": "SBO:0000247", "kegg.compound": "C00080"}}, {"charge": 3, "name": "Fe3+", "formula": "Fe", "compartment": "m", "id": "fe3_m", "annotation": {"bigg.metabolite": "fe3", "sbo": "SBO:0000247", "kegg.compound": "C14819"}}, {"charge": 0, "name": "L-Tyrosine", "formula": "C9H11NO3", "compartment": "e", "id": "tyr-L_e", "annotation": {"bigg.metabolite": "tyr-L", "sbo": "SBO:0000247", "kegg.compound": "C00082"}}, {"charge": 0, "name": "Acetaldehyde", "formula": "C2H4O", "compartment": "e", "id": "acald_e", "annotation": {"bigg.metabolite": "acald", "sbo": "SBO:0000247", "kegg.compound": "C00084"}}, {"charge": 0, "name": "Urea", "formula": "CH4N2O", "compartment": "e", "id": "urea_e", "annotation": {"bigg.metabolite": "urea", "sbo": "SBO:0000247", "kegg.compound": "C00086"}}, {"charge": 0, "name": "Sucrose", "formula": "C12H22O11", "compartment": "e", "id": "sucr_e", "annotation": {"bigg.metabolite": "sucr", "sbo": "SBO:0000247", "kegg.compound": "C00089"}}, {"charge": 0, "name": "Adenine", "formula": "C5H5N5", "compartment": "c", "id": "ade_c", "annotation": {"bigg.metabolite": "ade", "sbo": "SBO:0000247", "kegg.compound": "C00147"}}, {"charge": 0, "name": "globoside ", "formula": "C63.5654H112.5778N2.0O23.0", "compartment": "e", "id": "gbside_ce_e", "annotation": {"bigg.metabolite": "gbside_hs", "sbo": "SBO:0000247"}}, {"charge": 0, "name": "galactosyl glucosyl ceramide", "formula": "C49.5654H89.5778N1.0O13.0", "compartment": "e", "id": "galgluside_ce_e", "annotation": {"bigg.metabolite": "galgluside_hs", "sbo": "SBO:0000247"}}, {"charge": 0, "name": "glucocerebroside ", "formula": "C43.5654H79.5778N1.0O8.0", "compartment": "e", "id": "gluside_ce_e", "annotation": {"bigg.metabolite": "gluside_hs", "sbo": "SBO:0000247"}}, {"charge": 1, "name": "Sphingosine", "formula": "C19H40NO2", "compartment": "e", "id": "sphings_ce_e", "annotation": {"bigg.metabolite": "sphings", "sbo": "SBO:0000247"}}, {"charge": -1, "name": "Sphingosine 1-phosphate", "formula": "C19H39NO5P", "compartment": "e", "id": "sphs1p_ce_e", "annotation": {"bigg.metabolite": "sphs1p", "sbo": "SBO:0000247"}}, {"charge": 0, "name": "Xanthine", "formula": "C5H4N4O2", "compartment": "c", "id": "xan_c", "annotation": {"bigg.metabolite": "xan", "sbo": "SBO:0000247", "kegg.compound": "C00385"}}, {"charge": 0, "name": "Guanosine", "formula": "C10H13N5O5", "compartment": "c", "id": "gsn_c", "annotation": {"bigg.metabolite": "gsn", "sbo": "SBO:0000247", "kegg.compound": "C00387"}}, {"charge": 0, "name": "Dolichol", "formula": "C110H180O", "compartment": "c", "id": "dolichol_c", "annotation": {"bigg.metabolite": "dolichol", "sbo": "SBO:0000247", "kegg.compound": "C00381"}}, {"charge": 0, "name": "Methylglyoxal", "formula": "C3H4O2", "compartment": "c", "id": "mthgxl_c", "annotation": {"bigg.metabolite": "mthgxl", "sbo": "SBO:0000247", "kegg.compound": "C00546"}}, {"charge": 0, "name": "cis-11-retinol", "formula": "C20H30O", "compartment": "c", "id": "retinol-cis-11_c", "annotation": {"bigg.metabolite": "retinol-cis-11", "sbo": "SBO:0000247", "kegg.compound": "C00899"}}, {"charge": -1, "name": "Homogentisate", "formula": "C8H7O4", "compartment": "c", "id": "hgentis_c", "annotation": {"bigg.metabolite": "hgentis", "sbo": "SBO:0000247", "kegg.compound": "C00544"}}, {"charge": 0, "name": "Urate", "formula": "C5H4N4O3", "compartment": "c", "id": "urate_c", "annotation": {"bigg.metabolite": "urate", "sbo": "SBO:0000247", "kegg.compound": "C00366"}}, {"charge": -3, "name": "Diphosphate", "formula": "HO7P2", "compartment": "m", "id": "ppi_m", "annotation": {"bigg.metabolite": "ppi", "sbo": "SBO:0000247", "kegg.compound": "C00013"}}, {"charge": -4, "name": "Coenzyme A", "formula": "C21H32N7O16P3S", "compartment": "m", "id": "coa_m", "annotation": {"bigg.metabolite": "coa", "sbo": "SBO:0000247", "kegg.compound": "C00010"}}, {"charge": 0, "name": "CO2", "formula": "CO2", "compartment": "m", "id": "co2_m", "annotation": {"bigg.metabolite": "co2", "sbo": "SBO:0000247", "kegg.compound": "C00011"}}, {"charge": -2, "name": "Flavin adenine dinucleotide oxidized", "formula": "C27H31N9O15P2", "compartment": "m", "id": "fad_m", "annotation": {"bigg.metabolite": "fad", "sbo": "SBO:0000247", "kegg.compound": "C00016"}}, {"charge": -3, "name": "dTDP", "formula": "C10H13N2O11P2", "compartment": "c", "id": "dtdp_c", "annotation": {"bigg.metabolite": "dtdp", "sbo": "SBO:0000247", "kegg.compound": "C00363"}}, {"charge": 1, "name": "Ammonium", "formula": "H4N", "compartment": "m", "id": "nh4_m", "annotation": {"bigg.metabolite": "nh4", "sbo": "SBO:0000247", "kegg.compound": "C00014"}}, {"charge": -3, "name": "dGDP", "formula": "C10H12N5O10P2", "compartment": "c", "id": "dgdp_c", "annotation": {"bigg.metabolite": "dgdp", "sbo": "SBO:0000247", "kegg.compound": "C00361"}}, {"charge": -2, "name": "Pyridoxal 5'-phosphate", "formula": "C8H8NO6P", "compartment": "m", "id": "pydx5p_m", "annotation": {"bigg.metabolite": "pydx5p", "sbo": "SBO:0000247", "kegg.compound": "C00018"}}, {"charge": 1, "name": "S-Adenosyl-L-methionine", "formula": "C15H23N6O5S", "compartment": "m", "id": "amet_m", "annotation": {"bigg.metabolite": "amet", "sbo": "SBO:0000247", "kegg.compound": "C00019"}}, {"charge": 0, "name": "Soluble pool in bacterial diet", "formula": "C0.1997Co0.0004Fe0.0011H0.2682Mo0.0063N0.0539O0.1112P0.0089S0.0011Se0.0002", "compartment": "e", "id": "soluble_BAC_e", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -1, "name": "Methylselenol", "formula": "CH3Se", "compartment": "c", "id": "metsel_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C05703"}}, {"charge": -1, "name": "retinoyl glucuronide", "formula": "C26H35O8", "compartment": "c", "id": "retnglc_c", "annotation": {"bigg.metabolite": "retnglc", "sbo": "SBO:0000247", "kegg.compound": "C11061"}}, {"charge": -3, "name": "Citrate", "formula": "C6H5O7", "compartment": "e", "id": "cit_e", "annotation": {"bigg.metabolite": "cit", "sbo": "SBO:0000247", "kegg.compound": "C00158"}}, {"charge": -2, "name": "Selenate", "formula": "O4Se", "compartment": "e", "id": "sel_e", "annotation": {"bigg.metabolite": "sel", "sbo": "SBO:0000247", "kegg.compound": "C05697"}}, {"charge": 0, "name": "beta-Alanine", "formula": "C3H7NO2", "compartment": "c", "id": "ala-B_c", "annotation": {"bigg.metabolite": "ala-B", "sbo": "SBO:0000247", "kegg.compound": "C00099"}}, {"charge": -2, "name": "Glycerol 3-phosphate", "formula": "C3H7O6P", "compartment": "c", "id": "glyc3p_c", "annotation": {"bigg.metabolite": "glyc3p", "sbo": "SBO:0000247", "kegg.compound": "C00093"}}, {"charge": -2, "name": "Sulfite", "formula": "O3S", "compartment": "c", "id": "so3_c", "annotation": {"bigg.metabolite": "so3", "sbo": "SBO:0000247", "kegg.compound": "C00094"}}, {"charge": 0, "name": "D-Fructose", "formula": "C6H12O6", "compartment": "c", "id": "fru_c", "annotation": {"bigg.metabolite": "fru", "sbo": "SBO:0000247", "kegg.compound": "C00095"}}, {"charge": -2, "name": "GDP-D-mannose", "formula": "C16H23N5O16P2", "compartment": "c", "id": "gdpmann_c", "annotation": {"bigg.metabolite": "gdpmann", "sbo": "SBO:0000247", "kegg.compound": "C00096"}}, {"charge": 0, "name": "L-Cysteine", "formula": "C3H7NO2S", "compartment": "c", "id": "cys-L_c", "annotation": {"bigg.metabolite": "cys-L", "sbo": "SBO:0000247", "kegg.compound": "C00097"}}, {"charge": -2, "name": "5-Formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide", "formula": "C10H13N4O9P", "compartment": "c", "id": "fprica_c", "annotation": {"bigg.metabolite": "fprica", "sbo": "SBO:0000247", "kegg.compound": "C04734"}}, {"charge": 0, "name": "Ferrocytochrome C", "formula": "C42H42FeN8O8S2R4", "compartment": "m", "id": "focytC_m", "annotation": {"bigg.metabolite": "focytC", "sbo": "SBO:0000247", "kegg.compound": "C00126"}}, {"charge": -2, "name": "Oxidized glutathione", "formula": "C20H30N6O12S2", "compartment": "m", "id": "gthox_m", "annotation": {"bigg.metabolite": "gthox", "sbo": "SBO:0000247", "kegg.compound": "C00127"}}, {"charge": 1, "name": "Ferricytochrome c", "formula": "C42H42FeN8O8S2R4", "compartment": "m", "id": "ficytC_m", "annotation": {"bigg.metabolite": "ficytC", "sbo": "SBO:0000247", "kegg.compound": "C00125"}}, {"charge": -2, "name": "Fumarate", "formula": "C4H2O4", "compartment": "m", "id": "fum_m", "annotation": {"bigg.metabolite": "fum", "sbo": "SBO:0000247", "kegg.compound": "C00122"}}, {"charge": 0, "name": "L-Leucine", "formula": "C6H13NO2", "compartment": "m", "id": "leu-L_m", "annotation": {"bigg.metabolite": "leu-L", "sbo": "SBO:0000247", "kegg.compound": "C00123"}}, {"charge": -1, "name": "\"3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestanoate\"", "formula": "C27H45O5", "compartment": "m", "id": "thcholstoic_m", "annotation": {"bigg.metabolite": "thcholstoic", "sbo": "SBO:0000247", "kegg.compound": "C04722"}}, {"charge": -1, "name": "Acetoacetate", "formula": "C4H5O3", "compartment": "c", "id": "acac_c", "annotation": {"bigg.metabolite": "acac", "sbo": "SBO:0000247", "kegg.compound": "C00164"}}, {"charge": -1, "name": "Phenylpyruvate", "formula": "C9H7O3", "compartment": "c", "id": "phpyr_c", "annotation": {"bigg.metabolite": "phpyr", "sbo": "SBO:0000247", "kegg.compound": "C00166"}}, {"charge": -3, "name": "UDP-D-glucuronate", "formula": "C15H19N2O18P2", "compartment": "c", "id": "udpglcur_c", "annotation": {"bigg.metabolite": "udpglcur", "sbo": "SBO:0000247", "kegg.compound": "C00167"}}, {"charge": -1, "name": "Glycolate", "formula": "C2H3O3", "compartment": "c", "id": "glyclt_c", "annotation": {"bigg.metabolite": "glyclt", "sbo": "SBO:0000247", "kegg.compound": "C00160"}}, {"charge": -1, "name": "R total", "formula": "C18.5654H31.5778O2.0", "compartment": "c", "id": "Rtotal_c", "annotation": {"bigg.metabolite": "Rtotal", "sbo": "SBO:0000247", "kegg.compound": "C00162"}}, {"charge": -1, "name": "Propionate (n-C3:0)", "formula": "C3H5O2", "compartment": "c", "id": "ppa_c", "annotation": {"bigg.metabolite": "ppa", "sbo": "SBO:0000247", "kegg.compound": "C00163"}}, {"charge": -1, "name": "Hydroxypyruvate", "formula": "C3H3O4", "compartment": "c", "id": "hpyr_c", "annotation": {"bigg.metabolite": "hpyr", "sbo": "SBO:0000247", "kegg.compound": "C00168"}}, {"charge": -2, "name": "Carbamoyl phosphate", "formula": "CH2NO5P", "compartment": "c", "id": "cbp_c", "annotation": {"bigg.metabolite": "cbp", "sbo": "SBO:0000247", "kegg.compound": "C00169"}}, {"charge": 0, "name": "L-Kynurenine", "formula": "C10H12N2O3", "compartment": "e", "id": "Lkynr_e", "annotation": {"bigg.metabolite": "Lkynr", "sbo": "SBO:0000247", "kegg.compound": "C00328"}}, {"charge": 1, "name": "D-Glucosamine", "formula": "C6H14NO5", "compartment": "e", "id": "gam_e", "annotation": {"bigg.metabolite": "gam", "sbo": "SBO:0000247", "kegg.compound": "C00329"}}, {"charge": -2, "name": "CDP-ascarylose", "formula": "C15H23N3O14P2", "compartment": "c", "id": "cdpascl_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C17327"}}, {"charge": -2, "name": "Thiosulfate", "formula": "O3S2", "compartment": "e", "id": "tsul_e", "annotation": {"bigg.metabolite": "tsul", "sbo": "SBO:0000247", "kegg.compound": "C00320"}}, {"charge": -2, "name": "2-Oxoadipate", "formula": "C6H6O5", "compartment": "e", "id": "2oxoadp_e", "annotation": {"bigg.metabolite": "2oxoadp", "sbo": "SBO:0000247", "kegg.compound": "C00322"}}, {"charge": -2, "name": "(alpha-D-Mannosyl)6-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol", "formula": "C168H276N2O52P2", "compartment": "c", "id": "m6mpdol_c", "annotation": {"bigg.metabolite": ["m8mpdol_L", "m8mpdol_U"], "sbo": "SBO:0000247"}}, {"charge": -2, "name": "(alpha-D-Mannosyl)7-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol", "formula": "C174H286N2O57P2", "compartment": "c", "id": "m7mpdol_c", "annotation": {"bigg.metabolite": ["m7mpdol_L", "m7mpdol_U"], "sbo": "SBO:0000247"}}, {"charge": 0, "name": "Cys-Gly", "formula": "C5H10N2O3S", "compartment": "c", "id": "cgly_c", "annotation": {"bigg.metabolite": "cgly", "sbo": "SBO:0000247", "kegg.compound": "C01419"}}, {"charge": -2, "name": "(alpha-D-Mannosyl)5-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol", "formula": "C162H266N2O47P2", "compartment": "c", "id": "m5mpdol_c", "annotation": {"bigg.metabolite": ["m5mpdol_L", "um5mpdol_U"], "sbo": "SBO:0000247"}}, {"charge": 1, "name": "4-Trimethylammoniobutanal", "formula": "C7H16NO", "compartment": "c", "id": "4tmeabut_c", "annotation": {"bigg.metabolite": "4tmeabut", "sbo": "SBO:0000247", "kegg.compound": "C01149"}}, {"charge": -2, "name": "(alpha-D-Glucosyl)3-(alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol", "formula": "C198H326N2O77P2", "compartment": "c", "id": "g3m8mpdol_c", "annotation": {"bigg.metabolite": ["g3m8mpdol_L", "g3m8mpdol_U"], "sbo": "SBO:0000247"}}, {"charge": -2, "name": "3-Sulfinopyruvate", "formula": "C3H2O5S", "compartment": "m", "id": "3snpyr_m", "annotation": {"bigg.metabolite": "3snpyr", "sbo": "SBO:0000247", "kegg.compound": "C05527"}}, {"charge": -2, "name": "alpha-D-Glucosyl-(alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol", "formula": "C186H306N2O67P2", "compartment": "c", "id": "g1m8mpdol_c", "annotation": {"bigg.metabolite": ["g1m8mpdol_L", "g1m8mpdol_U"], "sbo": "SBO:0000247"}}, {"charge": -1, "name": "Succinic semialdehyde", "formula": "C4H5O3", "compartment": "m", "id": "sucsal_m", "annotation": {"bigg.metabolite": "sucsal", "sbo": "SBO:0000247", "kegg.compound": "C00232"}}, {"charge": -4, "name": "(S)-3-Hydroxybutanoyl-CoA", "formula": "C25H38N7O18P3S", "compartment": "c", "id": "3hbcoa_c", "annotation": {"bigg.metabolite": "3hbcoa", "sbo": "SBO:0000247", "kegg.compound": "C01144"}}, {"charge": 0, "name": "(alpha-D-Glucosyl)3-(alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)", "formula": "C92.0H154.0N4.0O73.0", "compartment": "c", "id": "g3m8masn_c", "annotation": {"bigg.metabolite": "g3m8masn", "sbo": "SBO:0000247"}}, {"charge": 0, "name": "(alpha-D-Glucosyl)2-(alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)", "formula": "C86.0H144.0N4.0O68.0", "compartment": "c", "id": "g2m8masn_c", "annotation": {"bigg.metabolite": "g2m8masn", "sbo": "SBO:0000247"}}, {"charge": -2, "name": "10-Formyltetrahydrofolate", "formula": "C20H21N7O7", "compartment": "m", "id": "10fthf_m", "annotation": {"bigg.metabolite": "10fthf", "sbo": "SBO:0000247", "kegg.compound": "C00234"}}, {"charge": -1, "name": "Beta cyanoalanine", "formula": "C4H5N2O2", "compartment": "m", "id": "cyanala_m", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C02512"}}, {"charge": -4, "name": "3-Oxodecanoyl-CoA", "formula": "C31H48N7O18P3S", "compartment": "c", "id": "3odcoa_c", "annotation": {"bigg.metabolite": "3odcoa", "sbo": "SBO:0000247", "kegg.compound": "C05265"}}, {"charge": -4, "name": "3-Oxotetradecanoyl-CoA", "formula": "C35H56N7O18P3S", "compartment": "c", "id": "3otdcoa_c", "annotation": {"bigg.metabolite": "3otdcoa", "sbo": "SBO:0000247", "kegg.compound": "C05261"}}, {"charge": -4, "name": "3-Oxododecanoyl-CoA", "formula": "C33H52N7O18P3S", "compartment": "c", "id": "3oddcoa_c", "annotation": {"bigg.metabolite": "3oddcoa", "sbo": "SBO:0000247", "kegg.compound": "C05263"}}, {"charge": -2, "name": "N-Carbamoyl-L-aspartate", "formula": "C5H6N2O5", "compartment": "e", "id": "cbasp_e", "annotation": {"bigg.metabolite": "cbasp", "sbo": "SBO:0000247", "kegg.compound": "C00438"}}, {"charge": -2, "name": "N-Formimidoyl-L-glutamate", "formula": "C6H8N2O4", "compartment": "e", "id": "forglu_e", "annotation": {"bigg.metabolite": "forglu", "sbo": "SBO:0000247", "kegg.compound": "C00439"}}, {"charge": 0, "name": "Reduced thioredoxin", "formula": "XH2", "compartment": "m", "id": "trdrd_m", "annotation": {"bigg.metabolite": "trdrd", "sbo": "SBO:0000247", "kegg.compound": "C00342"}}, {"charge": 0, "name": "Oxidized thioredoxin", "formula": "X", "compartment": "m", "id": "trdox_m", "annotation": {"bigg.metabolite": "trdox", "sbo": "SBO:0000247", "kegg.compound": "C00343"}}, {"charge": 0, "name": "N2-Acetyl-L-ornithine", "formula": "C7H14N2O3", "compartment": "e", "id": "acorn_e", "annotation": {"bigg.metabolite": "acorn", "sbo": "SBO:0000247", "kegg.compound": "C00437"}}, {"charge": 0, "name": "\"3alpha,7alpha,12alpha-Trihydroxy-5beta-cholestane\"", "formula": "C27H48O3", "compartment": "m", "id": "xoltriol_m", "annotation": {"bigg.metabolite": "xoltriol", "sbo": "SBO:0000247", "kegg.compound": "C05454"}}, {"charge": -4, "name": "trans-Dec-2-enoyl-CoA", "formula": "C31H48N7O17P3S", "compartment": "m", "id": "dc2coa_m", "annotation": {"bigg.metabolite": "dc2coa", "sbo": "SBO:0000247", "kegg.compound": "C05275"}}, {"charge": -4, "name": "Decanoyl-CoA (n-C10:0CoA)", "formula": "C31H50N7O17P3S", "compartment": "m", "id": "dcacoa_m", "annotation": {"bigg.metabolite": "dcacoa", "sbo": "SBO:0000247", "kegg.compound": "C05274"}}, {"charge": -4, "name": "trans-Oct-2-enoyl-CoA", "formula": "C29H44N7O17P3S", "compartment": "m", "id": "oc2coa_m", "annotation": {"bigg.metabolite": "oc2coa", "sbo": "SBO:0000247", "kegg.compound": "C05276"}}, {"charge": -4, "name": "trans-Hex-2-enoyl-CoA", "formula": "C27H40N7O17P3S", "compartment": "m", "id": "hx2coa_m", "annotation": {"bigg.metabolite": "hx2coa", "sbo": "SBO:0000247", "kegg.compound": "C05271"}}, {"charge": -4, "name": "Hexanoyl-CoA (n-C6:0CoA)", "formula": "C27H42N7O17P3S", "compartment": "m", "id": "hxcoa_m", "annotation": {"bigg.metabolite": "hxcoa", "sbo": "SBO:0000247", "kegg.compound": "C05270"}}, {"charge": -4, "name": "trans-Tetradec-2-enoyl-CoA", "formula": "C35H56N7O17P3S", "compartment": "m", "id": "td2coa_m", "annotation": {"bigg.metabolite": "td2coa", "sbo": "SBO:0000247", "kegg.compound": "C05273"}}, {"charge": -4, "name": "trans-Hexadec-2-enoyl-CoA", "formula": "C37H60N7O17P3S", "compartment": "m", "id": "hdd2coa_m", "annotation": {"bigg.metabolite": "hdd2coa", "sbo": "SBO:0000247", "kegg.compound": "C05272"}}, {"charge": 1, "name": "Histone N6-methyl-L-lysine", "formula": "XC7H15N2O", "compartment": "c", "id": "Nmelys_c", "annotation": {"bigg.metabolite": "Nmelys", "sbo": "SBO:0000247", "kegg.compound": "C03702"}}, {"charge": 0, "name": "Galactitol", "formula": "C6H14O6", "compartment": "e", "id": "galt_e", "annotation": {"bigg.metabolite": "galt", "sbo": "SBO:0000247", "kegg.compound": "C01697"}}, {"charge": 0, "name": "O-Acetylcarnitine", "formula": "C9H17NO4", "compartment": "c", "id": "acrn_c", "annotation": {"bigg.metabolite": "acrn", "sbo": "SBO:0000247", "kegg.compound": "C02571"}}, {"charge": 0, "name": "Guanosine", "formula": "C10H13N5O5", "compartment": "m", "id": "gsn_m", "annotation": {"bigg.metabolite": "gsn", "sbo": "SBO:0000247", "kegg.compound": "C00387"}}, {"charge": -1, "name": "Folate", "formula": "C19H18N7O6", "compartment": "e", "id": "fol_e", "annotation": {"bigg.metabolite": "fol", "sbo": "SBO:0000247", "kegg.compound": "C00504"}}, {"charge": -1, "name": "L-Cysteate", "formula": "C3H6NO5S", "compartment": "e", "id": "Lcyst_e", "annotation": {"bigg.metabolite": "Lcyst", "sbo": "SBO:0000247", "kegg.compound": "C00506"}}, {"charge": 0, "name": "apo iron-sulfur cluster protein", "formula": "X", "compartment": "m", "id": "apoISclustprot_m", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 6, "name": "Iron-sulfur cluster protein", "formula": "XFe2S2", "compartment": "m", "id": "ISclustprot_m", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -1, "name": "Pyridoxamine 5'-phosphate", "formula": "C8H12N2O5P", "compartment": "m", "id": "pyam5p_m", "annotation": {"bigg.metabolite": "pyam5p", "sbo": "SBO:0000247", "kegg.compound": "C00647"}}, {"charge": 0, "name": "Ascaroside 2", "formula": "C12H22O5", "compartment": "c", "id": "ascr2_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 0, "name": "Random peptide (special aminoacid carrier)", "formula": "X", "compartment": "c", "id": "pepX_c", "annotation": {"bigg.metabolite": "pepd", "sbo": "SBO:0000247"}}, {"charge": 1, "name": "Histone N6,N6,N6-trimethyl-L-lysine", "formula": "XC9H19N2O", "compartment": "c", "id": "Ntmelys_c", "annotation": {"bigg.metabolite": "Ntmelys", "sbo": "SBO:0000247"}}, {"charge": 0, "name": "Tropocollagen L-tyrosine (cross-linked)", "formula": "X", "compartment": "c", "id": "tropcollgtyrX_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 2, "name": "Collagen", "formula": "C13.006941H23.093343N3.879621O4.41654S0.132888", "compartment": "c", "id": "collg_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 0, "name": "Minor components of biomass", "formula": "X", "compartment": "c", "id": "biomass_minor_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 0, "name": "Peptide L-asparagine", "formula": "XC4H6N2O2", "compartment": "c", "id": "pepasn_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 0, "name": "Peptide 3-hydroxy-L-asparagine", "formula": "XC4H6N2O3", "compartment": "c", "id": "pepasn3oh_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 0, "name": "Nicotinate D-ribonucleoside", "formula": "C11H13NO6", "compartment": "c", "id": "nicrns_c", "annotation": {"bigg.metabolite": "nicrns", "sbo": "SBO:0000247", "kegg.compound": "C05841"}}, {"charge": -1, "name": "5-L-Glutamyl-taurine", "formula": "C7H13N2O6S", "compartment": "c", "id": "glutaur_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C05844"}}, {"charge": 0, "name": "Deoxycytidine", "formula": "C9H13N3O4", "compartment": "e", "id": "dcyt_e", "annotation": {"bigg.metabolite": "dcyt", "sbo": "SBO:0000247", "kegg.compound": "C00881"}}, {"charge": -1, "name": "enol-Phenylpyruvate", "formula": "C9H7O3", "compartment": "e", "id": "enphpyr_e", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C02763"}}, {"charge": 1, "name": "L-Seryl-tRNA(Sec)", "formula": "C3H7NO3R", "compartment": "c", "id": "sertrna_sec_c", "annotation": {"bigg.metabolite": "sertrna(sec)", "sbo": "SBO:0000247", "kegg.compound": "C06481"}}, {"charge": -4, "name": "dihomo-gamma-linolenyl coenzyme A", "formula": "C41H64N7O17P3S", "compartment": "m", "id": "dlnlcgcoa_m", "annotation": {"bigg.metabolite": "dlnlcgcoa", "sbo": "SBO:0000247", "kegg.compound": "C03595"}}, {"charge": -4, "name": "gamma-linolenoyl-CoA", "formula": "C39H60N7O17P3S", "compartment": "c", "id": "lnlncgcoa_c", "annotation": {"bigg.metabolite": "lnlncgcoa", "sbo": "SBO:0000247", "kegg.compound": "C03035"}}, {"charge": -1, "name": "3-Hydroxy-2-methylpropanoate", "formula": "C4H7O3", "compartment": "c", "id": "3hmp_c", "annotation": {"bigg.metabolite": "3hmp", "sbo": "SBO:0000247", "kegg.compound": "C06001"}}, {"charge": -2, "name": "L-sulfolactate", "formula": "C3H4O6S", "compartment": "m", "id": "sl-L_m", "annotation": {"bigg.metabolite": "sl-L", "sbo": "SBO:0000247", "kegg.compound": "C11499"}}, {"charge": -1, "name": "Indole-3-acetate", "formula": "C10H8NO2", "compartment": "c", "id": "ind3ac_c", "annotation": {"bigg.metabolite": "ind3ac", "sbo": "SBO:0000247", "kegg.compound": "C00954"}}, {"charge": -1, "name": "Mercaptopyruvate", "formula": "C3H3O3S", "compartment": "c", "id": "mercppyr_c", "annotation": {"bigg.metabolite": "mercppyr", "sbo": "SBO:0000247", "kegg.compound": "C00957"}}, {"charge": -1, "name": "L-2-Aminoadipate", "formula": "C6H10NO4", "compartment": "c", "id": "L2aadp_c", "annotation": {"bigg.metabolite": "L2aadp", "sbo": "SBO:0000247", "kegg.compound": "C00956"}}, {"charge": 0, "name": "triacylglycerol", "formula": "C54.9054H99.5282O6.0", "compartment": "c", "id": "tag_c", "annotation": {"bigg.metabolite": "tag_hs", "sbo": "SBO:0000247", "kegg.compound": "C00422"}}, {"charge": -1, "name": "Prostaglandin H2", "formula": "C20H31O5", "compartment": "c", "id": "prostgh2_c", "annotation": {"bigg.metabolite": "prostgh2", "sbo": "SBO:0000247", "kegg.compound": "C00427"}}, {"charge": 0, "name": "\"5,6-dihydrouracil\"", "formula": "C4H6N2O2", "compartment": "c", "id": "56dura_c", "annotation": {"bigg.metabolite": "56dura", "sbo": "SBO:0000247", "kegg.compound": "C00429"}}, {"charge": 0, "name": "11-cis-Retinyl palmitate", "formula": "C36H60O2", "compartment": "c", "id": "retpalm-cis-11_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C03455"}}, {"charge": 0, "name": "1-Alkenyl-2-acylglycerol", "formula": "C39.5654H72.5778O4.0", "compartment": "c", "id": "alkenac2g_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C03454"}}, {"charge": -4, "name": "\"3alpha,7alpha,12alpha-Trihydroxy-5beta-cholest-24-enoyl-CoA\"", "formula": "C48H74N7O20P3S", "compartment": "c", "id": "cholcoads_c", "annotation": {"bigg.metabolite": "cholcoads", "sbo": "SBO:0000247", "kegg.compound": "C05460"}}, {"charge": -4, "name": "\"3alpha,7alpha,12alpha-Trihydroxy-5beta-24-oxocholestanoyl-CoA\"", "formula": "C48H74N7O21P3S", "compartment": "c", "id": "cholcoaone_c", "annotation": {"bigg.metabolite": "cholcoaone", "sbo": "SBO:0000247", "kegg.compound": "C05467"}}, {"charge": 0, "name": "Ubiquinone", "formula": "C14H18O4", "compartment": "c", "id": "q_c", "annotation": {"bigg.metabolite": "q", "sbo": "SBO:0000247", "kegg.compound": "C00399"}}, {"charge": 1, "name": "Tryptamine", "formula": "C10H13N2", "compartment": "c", "id": "trypta_c", "annotation": {"bigg.metabolite": "trypta", "sbo": "SBO:0000247", "kegg.compound": "C00398"}}, {"charge": 0, "name": "Procollagen trans-4-hydroxy-L-proline", "formula": "XOH", "compartment": "c", "id": "pcollg4hpro_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C04398"}}, {"charge": 0, "name": "Ubiquinol", "formula": "C14H20O4", "compartment": "c", "id": "qh2_c", "annotation": {"bigg.metabolite": "qh2", "sbo": "SBO:0000247", "kegg.compound": "C00390"}}, {"charge": -2, "name": "GDP-D-glucose", "formula": "C16H23N5O16P2", "compartment": "c", "id": "gdpg_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C00394"}}, {"charge": 0, "name": "Deoxyadenosine", "formula": "C10H13N5O3", "compartment": "c", "id": "dad-2_c", "annotation": {"bigg.metabolite": "dad-2", "sbo": "SBO:0000247", "kegg.compound": "C00559"}}, {"charge": 1, "name": "L-Alanyl-tRNA(Ala)", "formula": "C3H7NO2R", "compartment": "c", "id": "alatrna_c", "annotation": {"bigg.metabolite": "alatrna", "sbo": "SBO:0000247", "kegg.compound": "C00886"}}, {"charge": 0, "name": "Deoxycytidine", "formula": "C9H13N3O4", "compartment": "c", "id": "dcyt_c", "annotation": {"bigg.metabolite": "dcyt", "sbo": "SBO:0000247", "kegg.compound": "C00881"}}, {"charge": 0, "name": "H2O", "formula": "H2O", "compartment": "m", "id": "h2o_m", "annotation": {"bigg.metabolite": "h2o", "sbo": "SBO:0000247", "kegg.compound": "C00001"}}, {"charge": -1, "name": "Nicotinamide adenine dinucleotide", "formula": "C21H26N7O14P2", "compartment": "m", "id": "nad_m", "annotation": {"bigg.metabolite": "nad", "sbo": "SBO:0000247", "kegg.compound": "C00003"}}, {"charge": -4, "name": "ATP", "formula": "C10H12N5O13P3", "compartment": "m", "id": "atp_m", "annotation": {"bigg.metabolite": "atp", "sbo": "SBO:0000247", "kegg.compound": "C00002"}}, {"charge": -4, "name": "Nicotinamide adenine dinucleotide phosphate - reduced", "formula": "C21H26N7O17P3", "compartment": "m", "id": "nadph_m", "annotation": {"bigg.metabolite": "nadph", "sbo": "SBO:0000247", "kegg.compound": "C00005"}}, {"charge": -2, "name": "Nicotinamide adenine dinucleotide - reduced", "formula": "C21H27N7O14P2", "compartment": "m", "id": "nadh_m", "annotation": {"bigg.metabolite": "nadh", "sbo": "SBO:0000247", "kegg.compound": "C00004"}}, {"charge": 0, "name": "O2", "formula": "O2", "compartment": "m", "id": "o2_m", "annotation": {"bigg.metabolite": "o2", "sbo": "SBO:0000247", "kegg.compound": "C00007"}}, {"charge": -3, "name": "Nicotinamide adenine dinucleotide phosphate", "formula": "C21H25N7O17P3", "compartment": "m", "id": "nadp_m", "annotation": {"bigg.metabolite": "nadp", "sbo": "SBO:0000247", "kegg.compound": "C00006"}}, {"charge": -2, "name": "Phosphate", "formula": "HO4P", "compartment": "m", "id": "pi_m", "annotation": {"bigg.metabolite": "pi", "sbo": "SBO:0000247", "kegg.compound": "C00009"}}, {"charge": -3, "name": "ADP", "formula": "C10H12N5O10P2", "compartment": "m", "id": "adp_m", "annotation": {"bigg.metabolite": "adp", "sbo": "SBO:0000247", "kegg.compound": "C00008"}}, {"charge": -1, "name": "R total 2 position", "formula": "C18.5654H31.5778O2.0", "compartment": "e", "id": "Rtotal2_e", "annotation": {"bigg.metabolite": ["Rtotal", "Rtotal2", "Rtotal3"], "sbo": "SBO:0000247"}}, {"charge": 0, "name": "Xylitol", "formula": "C5H12O5", "compartment": "c", "id": "xylt_c", "annotation": {"bigg.metabolite": "xylt", "sbo": "SBO:0000247", "kegg.compound": "C00379"}}, {"charge": 1, "name": "Thiamin", "formula": "C12H17N4OS", "compartment": "c", "id": "thm_c", "annotation": {"bigg.metabolite": "thm", "sbo": "SBO:0000247", "kegg.compound": "C00378"}}, {"charge": 0, "name": "L-Threonine", "formula": "C4H9NO3", "compartment": "e", "id": "thr-L_e", "annotation": {"bigg.metabolite": "thr-L", "sbo": "SBO:0000247", "kegg.compound": "C00188"}}, {"charge": 1, "name": "Ethanolamine", "formula": "C2H8NO", "compartment": "e", "id": "etha_e", "annotation": {"bigg.metabolite": "etha", "sbo": "SBO:0000247", "kegg.compound": "C00189"}}, {"charge": 0, "name": "D-Xylose", "formula": "C5H10O5", "compartment": "e", "id": "xyl-D_e", "annotation": {"bigg.metabolite": "xyl-D", "sbo": "SBO:0000247", "kegg.compound": "C00181"}}, {"charge": 0, "name": "L-Valine", "formula": "C5H11NO2", "compartment": "e", "id": "val-L_e", "annotation": {"bigg.metabolite": "val-L", "sbo": "SBO:0000247", "kegg.compound": "C00183"}}, {"charge": 0, "name": "Cellobiose", "formula": "C12H22O11", "compartment": "e", "id": "clb_e", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C00185"}}, {"charge": -1, "name": "L-Lactate", "formula": "C3H5O3", "compartment": "e", "id": "lac-L_e", "annotation": {"bigg.metabolite": "lac-L", "sbo": "SBO:0000247", "kegg.compound": "C00186"}}, {"charge": 0, "name": "Cholesterol", "formula": "C27H46O", "compartment": "e", "id": "chsterol_e", "annotation": {"bigg.metabolite": "chsterol", "sbo": "SBO:0000247", "kegg.compound": "C00187"}}, {"charge": 0, "name": "Urea", "formula": "CH4N2O", "compartment": "c", "id": "urea_c", "annotation": {"bigg.metabolite": "urea", "sbo": "SBO:0000247", "kegg.compound": "C00086"}}, {"charge": -2, "name": "D-Fructose 6-phosphate", "formula": "C6H11O9P", "compartment": "c", "id": "f6p_c", "annotation": {"bigg.metabolite": "f6p", "sbo": "SBO:0000247", "kegg.compound": "C00085"}}, {"charge": 0, "name": "Acetaldehyde", "formula": "C2H4O", "compartment": "c", "id": "acald_c", "annotation": {"bigg.metabolite": "acald", "sbo": "SBO:0000247", "kegg.compound": "C00084"}}, {"charge": -5, "name": "Malonyl-CoA", "formula": "C24H33N7O19P3S", "compartment": "c", "id": "malcoa_c", "annotation": {"bigg.metabolite": "malcoa", "sbo": "SBO:0000247", "kegg.compound": "C00083"}}, {"charge": 0, "name": "L-Tyrosine", "formula": "C9H11NO3", "compartment": "c", "id": "tyr-L_c", "annotation": {"bigg.metabolite": "tyr-L", "sbo": "SBO:0000247", "kegg.compound": "C00082"}}, {"charge": -4, "name": "ITP", "formula": "C10H11N4O14P3", "compartment": "c", "id": "itp_c", "annotation": {"bigg.metabolite": "itp", "sbo": "SBO:0000247", "kegg.compound": "C00081"}}, {"charge": 1, "name": "H+", "formula": "H", "compartment": "c", "id": "h_c", "annotation": {"bigg.metabolite": "h", "sbo": "SBO:0000247", "kegg.compound": "C00080"}}, {"charge": -1, "name": "2-(Formamido)-N1-(5-phospho-D-ribosyl)acetamidine", "formula": "C8H15N3O8P", "compartment": "c", "id": "fpram_c", "annotation": {"bigg.metabolite": "fpram", "sbo": "SBO:0000247", "kegg.compound": "C04640"}}, {"charge": 0, "name": "Sucrose", "formula": "C12H22O11", "compartment": "c", "id": "sucr_c", "annotation": {"bigg.metabolite": "sucr", "sbo": "SBO:0000247", "kegg.compound": "C00089"}}, {"charge": -1, "name": "Retinoate", "formula": "C20H27O2", "compartment": "c", "id": "retn_c", "annotation": {"bigg.metabolite": "retn", "sbo": "SBO:0000247", "kegg.compound": "C00777"}}, {"charge": -1, "name": "5-Oxoproline", "formula": "C5H6NO3", "compartment": "e", "id": "5oxpro_e", "annotation": {"bigg.metabolite": "5oxpro", "sbo": "SBO:0000247", "kegg.compound": "C01879"}}, {"charge": 0, "name": "L-Histidine", "formula": "C6H9N3O2", "compartment": "m", "id": "his-L_m", "annotation": {"bigg.metabolite": "his-L", "sbo": "SBO:0000247", "kegg.compound": "C00135"}}, {"charge": -4, "name": "Butanoyl-CoA", "formula": "C25H38N7O17P3S", "compartment": "m", "id": "btcoa_m", "annotation": {"bigg.metabolite": "btcoa", "sbo": "SBO:0000247", "kegg.compound": "C00136"}}, {"charge": -4, "name": "dATP", "formula": "C10H12N5O12P3", "compartment": "m", "id": "datp_m", "annotation": {"bigg.metabolite": "datp", "sbo": "SBO:0000247", "kegg.compound": "C00131"}}, {"charge": -4, "name": "\"Adenosine 3',5'-bisphosphate\"", "formula": "C10H11N5O10P2", "compartment": "e", "id": "pap_e", "annotation": {"bigg.metabolite": "pap", "sbo": "SBO:0000247", "kegg.compound": "C00054"}}, {"charge": -1, "name": "Reduced glutathione", "formula": "C10H16N3O6S", "compartment": "e", "id": "gthrd_e", "annotation": {"bigg.metabolite": "gthrd", "sbo": "SBO:0000247", "kegg.compound": "C00051"}}, {"charge": 0, "name": "L-Carnitine", "formula": "C7H15NO3", "compartment": "e", "id": "crn_e", "annotation": {"bigg.metabolite": "crn", "sbo": "SBO:0000247", "kegg.compound": "C00318"}}, {"charge": -1, "name": "Formate", "formula": "CH1O2", "compartment": "e", "id": "for_e", "annotation": {"bigg.metabolite": "for", "sbo": "SBO:0000247", "kegg.compound": "C00058"}}, {"charge": -2, "name": "Sulfate", "formula": "O4S", "compartment": "e", "id": "so4_e", "annotation": {"bigg.metabolite": "so4", "sbo": "SBO:0000247", "kegg.compound": "C00059"}}, {"charge": 0, "name": "5-Methylthioadenosine", "formula": "C11H15N5O3S", "compartment": "c", "id": "5mta_c", "annotation": {"bigg.metabolite": "5mta", "sbo": "SBO:0000247", "kegg.compound": "C00170"}}, {"charge": 0, "name": "Thymine", "formula": "C5H6N2O2", "compartment": "c", "id": "thym_c", "annotation": {"bigg.metabolite": "thym", "sbo": "SBO:0000247", "kegg.compound": "C00178"}}, {"charge": -1, "name": "2-Hydroxybutyrate", "formula": "C4H7O3", "compartment": "e", "id": "2hb_e", "annotation": {"bigg.metabolite": "2hb", "sbo": "SBO:0000247", "kegg.compound": "C05984"}}, {"charge": 0, "name": "\"7alpha,12alpha-Dihydroxycholest-4-en-3-one\"", "formula": "C27H44O3", "compartment": "c", "id": "xoldiolone_c", "annotation": {"bigg.metabolite": "xoldiolone", "sbo": "SBO:0000247", "kegg.compound": "C17339"}}, {"charge": -1, "name": "7alpha-Hydroxy-3-oxo-4-cholestenoate", "formula": "C27H41O4", "compartment": "c", "id": "7a3o4chlstnt_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C17337"}}, {"charge": 0, "name": "7alpha,26-Dihydroxy-4-cholesten-3-one", "formula": "C27H44O3", "compartment": "c", "id": "xol27one_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C17336"}}, {"charge": -2, "name": "Flavin adenine dinucleotide reduced", "formula": "C27H33N9O15P2", "compartment": "m", "id": "fadh2_m", "annotation": {"bigg.metabolite": "fadh2", "sbo": "SBO:0000247", "kegg.compound": "C01352"}}, {"charge": 0, "name": "7alpha,25-Dihydroxy-4-cholesten-3-one", "formula": "C27H44O3", "compartment": "c", "id": "xol25one_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C17332"}}, {"charge": 0, "name": "(alpha-D-mannosyl)8-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)", "formula": "C74.0H124.0N4.0O58.0", "compartment": "c", "id": "m8masn_c", "annotation": {"bigg.metabolite": "m8masn", "sbo": "SBO:0000247"}}, {"charge": -1, "name": "3-(4-Hydroxyphenyl)pyruvate", "formula": "C9H7O4", "compartment": "c", "id": "34hpp_c", "annotation": {"bigg.metabolite": "34hpp", "sbo": "SBO:0000247", "kegg.compound": "C01179"}}, {"charge": 0, "name": "(N-acetyl-D-glucosaminyl-(alpha-D-mannosyl)4-beta-D-mannosyl-diacetylchitobiosyl)-L-asparagine (protein)", "formula": "C58.0H97.0N5.0O43.0", "compartment": "c", "id": "nm4masn_c", "annotation": {"bigg.metabolite": "nm4masn", "sbo": "SBO:0000247"}}, {"charge": 0, "name": "(alpha-D-mannosyl)4-beta-D-mannosyl-diacetylchitobiosyl-L-asparagine (protein)", "formula": "C50.0H84.0N4.0O38.0", "compartment": "c", "id": "m4masn_c", "annotation": {"bigg.metabolite": "m4masn", "sbo": "SBO:0000247"}}, {"charge": 0, "name": "((N-acetyl-D-glucosaminyl)2-(alpha-D-mannosyl)2-beta-D-mannosyl-diacetylchitobiosyl)-L-asparagine (protein)", "formula": "C54.0H90.0N6.0O38.0", "compartment": "c", "id": "n2m2masn_c", "annotation": {"bigg.metabolite": "n2m2masn", "sbo": "SBO:0000247"}}, {"charge": 0, "name": "(N-acetyl-D-glucosaminyl-(alpha-D-mannosyl)2-beta-D-mannosyl-diacetylchitobiosyl)-L-asparagine (protein)", "formula": "C46.0H77.0N5.0O33.0", "compartment": "c", "id": "nm2masn_c", "annotation": {"bigg.metabolite": "nm2masn", "sbo": "SBO:0000247"}}, {"charge": 0, "name": "{[galactosyl-(1,4)-N-Acetyl-glucosaminyl-(1,2)-mannosyl-(1,3)-],[N-acetyl-glucosaminyl-(1,2)-mannosyl-(1,6)-]mannosyl-(1,4)-N-acetyl-glucosaminyl-(1,4)-[fucosyl-(1,6)]-N-acetyl-glucosaminyl}asparagine", "formula": "C72.0H120.0N6.0O52.0", "compartment": "c", "id": "l2fn2m2masn_c", "annotation": {"bigg.metabolite": "l2fn2m2masn", "sbo": "SBO:0000247"}}, {"charge": 0, "name": "N4-{N-Acetyl-beta-D-glucosaminyl-(1,2)-alpha-D-mannosyl-(1,3)-[N-acetyl-beta-D-glucosaminyl-(1,2)-alpha-D-mannosyl-(1,6)]-beta-D-mannosyl-(1,4)-N-acetyl-beta-D-glucosaminyl-(1,4)-[alpha-L-fucosyl-(1,6)]-N-acetyl-beta-D-glucosaminyl}asparagine", "formula": "C60.0H100.0N6.0O42.0", "compartment": "c", "id": "fn2m2masn_c", "annotation": {"bigg.metabolite": "fn2m2masn", "sbo": "SBO:0000247"}}, {"charge": 0, "name": "M4Gn2", "formula": "C44.0H74.0N4.0O33.0", "compartment": "c", "id": "m3masn_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 0, "name": "M4Gn3", "formula": "C52.0H87.0N5.0O38.0", "compartment": "c", "id": "nm3masn_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -2, "name": "beta-D-glucose 6-phosphate", "formula": "C6H11O9P", "compartment": "c", "id": "g6p-B_c", "annotation": {"bigg.metabolite": "g6p-B", "sbo": "SBO:0000247", "kegg.compound": "C01172"}}, {"charge": -1, "name": "Malonate semialdehyde", "formula": "C3H3O3", "compartment": "m", "id": "msa_m", "annotation": {"bigg.metabolite": "msa", "sbo": "SBO:0000247", "kegg.compound": "C00222"}}, {"charge": -2, "name": "1D-myo-Inositol 1-phosphate", "formula": "C6H11O9P", "compartment": "c", "id": "mi1p-D_c", "annotation": {"bigg.metabolite": "mi1p-D", "sbo": "SBO:0000247", "kegg.compound": "C01177"}}, {"charge": -1, "name": "Prostaglandin H2", "formula": "C20H31O5", "compartment": "e", "id": "prostgh2_e", "annotation": {"bigg.metabolite": "prostgh2", "sbo": "SBO:0000247", "kegg.compound": "C00427"}}, {"charge": 0, "name": "triacylglycerol", "formula": "C54.9054H99.5282O6.0", "compartment": "e", "id": "tag_e", "annotation": {"bigg.metabolite": "tag_hs", "sbo": "SBO:0000247", "kegg.compound": "C00422"}}, {"charge": -10, "name": "\"1D-myo-Inositol 1,3,4,5,6-pentakisphosphate\"", "formula": "C6H7O21P5", "compartment": "c", "id": "mi13456p_c", "annotation": {"bigg.metabolite": "mi13456p", "sbo": "SBO:0000247", "kegg.compound": "C01284"}}, {"charge": -1, "name": "3-Ureidoisobutyrate", "formula": "C5H9N2O3", "compartment": "e", "id": "3uib_e", "annotation": {"bigg.metabolite": "3uib", "sbo": "SBO:0000247", "kegg.compound": "C05100"}}, {"charge": 1, "name": "L-Seryl-tRNA(Ser)", "formula": "C3H7NO3R", "compartment": "c", "id": "sertrna_c", "annotation": {"bigg.metabolite": "sertrna", "sbo": "SBO:0000247", "kegg.compound": "C02553"}}, {"charge": -4, "name": "trans-Hexadec-2-enoyl-CoA", "formula": "C37H60N7O17P3S", "compartment": "c", "id": "hdd2coa_c", "annotation": {"bigg.metabolite": "hdd2coa", "sbo": "SBO:0000247", "kegg.compound": "C05272"}}, {"charge": -1, "name": "N-Acetyl-D-glucosaminylphosphatidylinositol", "formula": "C54.1308H92.1556N1.0O18.0P1.0", "compartment": "c", "id": "acgpail_c", "annotation": {"bigg.metabolite": "acgpail_hs", "sbo": "SBO:0000247", "kegg.compound": "C01288"}}, {"charge": -4, "name": "Hexanoyl-CoA (n-C6:0CoA)", "formula": "C27H42N7O17P3S", "compartment": "c", "id": "hxcoa_c", "annotation": {"bigg.metabolite": "hxcoa", "sbo": "SBO:0000247", "kegg.compound": "C05270"}}, {"charge": -4, "name": "trans-Dec-2-enoyl-CoA", "formula": "C31H48N7O17P3S", "compartment": "c", "id": "dc2coa_c", "annotation": {"bigg.metabolite": "dc2coa", "sbo": "SBO:0000247", "kegg.compound": "C05275"}}, {"charge": 1, "name": "L-Valyl-tRNA(Val)", "formula": "C5H11NO2R", "compartment": "c", "id": "valtrna_c", "annotation": {"bigg.metabolite": "valtrna", "sbo": "SBO:0000247", "kegg.compound": "C02554"}}, {"charge": -5, "name": "Hydroxymethylglutaryl-CoA", "formula": "C27H39N7O20P3S", "compartment": "m", "id": "hmgcoa_m", "annotation": {"bigg.metabolite": "hmgcoa", "sbo": "SBO:0000247", "kegg.compound": "C00356"}}, {"charge": 0, "name": "Phosphatidylethanolamine", "formula": "C42.1308H75.1556N1.0O8.0P1.0", "compartment": "m", "id": "pe_m", "annotation": {"bigg.metabolite": ["pe181", "pe180", "pe161", "pe160", "pe141", "pe140", "pe120", "pe_SA", "pe_hs", "pe_EC", "pe_HP", "pe_SC"], "sbo": "SBO:0000247", "kegg.compound": "C00350"}}, {"charge": -4, "name": "\"2-Amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)dihydropteridine triphosphate\"", "formula": "C9H12N5O13P3", "compartment": "c", "id": "ahdt_c", "annotation": {"bigg.metabolite": "ahdt", "sbo": "SBO:0000247", "kegg.compound": "C04895"}}, {"charge": -5, "name": "Hydroxymethylglutaryl-CoA", "formula": "C27H39N7O20P3S", "compartment": "c", "id": "hmgcoa_c", "annotation": {"bigg.metabolite": "hmgcoa", "sbo": "SBO:0000247", "kegg.compound": "C00356"}}, {"charge": 0, "name": "\"3,4-Dihydroxy-L-phenylalanine\"", "formula": "C9H11NO4", "compartment": "c", "id": "34dhphe_c", "annotation": {"bigg.metabolite": "34dhphe", "sbo": "SBO:0000247", "kegg.compound": "C00355"}}, {"charge": -2, "name": "AMP", "formula": "C10H12N5O7P", "compartment": "m", "id": "amp_m", "annotation": {"bigg.metabolite": "amp", "sbo": "SBO:0000247", "kegg.compound": "C00020"}}, {"charge": -3, "name": "\"trans,trans,cis-Geranylgeranyl diphosphate\"", "formula": "C20H33O7P2", "compartment": "c", "id": "ttc-ggdp_c", "annotation": {"bigg.metabolite": "ttc-ggdp", "sbo": "SBO:0000247", "kegg.compound": "C00353"}}, {"charge": -2, "name": "2-Oxoglutarate", "formula": "C5H4O5", "compartment": "m", "id": "akg_m", "annotation": {"bigg.metabolite": "akg", "sbo": "SBO:0000247", "kegg.compound": "C00026"}}, {"charge": -4, "name": "Acetyl-CoA", "formula": "C23H34N7O17P3S", "compartment": "m", "id": "accoa_m", "annotation": {"bigg.metabolite": "accoa", "sbo": "SBO:0000247", "kegg.compound": "C00024"}}, {"charge": 0, "name": "D-3-Amino-isobutanoate", "formula": "C4H9NO2", "compartment": "e", "id": "3aib-D_e", "annotation": {"bigg.metabolite": "3aib-D", "sbo": "SBO:0000247", "kegg.compound": "C01205"}}, {"charge": 0, "name": "\"3,5-Diiodo-L-tyrosine\"", "formula": "C9H9I2NO3", "compartment": "e", "id": "35diotyr_e", "annotation": {"bigg.metabolite": "35diotyr", "sbo": "SBO:0000247", "kegg.compound": "C01060"}}, {"charge": -1, "name": "linoleic acid (all cis C18:2) n-6", "formula": "C18H31O2", "compartment": "c", "id": "lnlc_c", "annotation": {"bigg.metabolite": "lnlc", "sbo": "SBO:0000247", "kegg.compound": "C01595"}}, {"charge": -1, "name": "3-(4-Hydroxyphenyl)pyruvate", "formula": "C9H7O4", "compartment": "m", "id": "34hpp_m", "annotation": {"bigg.metabolite": "34hpp", "sbo": "SBO:0000247", "kegg.compound": "C01179"}}, {"charge": 0, "name": "Tropocollagen L-tyrosine (to be cross-linked)", "formula": "XH", "compartment": "c", "id": "tropcollgtyr_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 0, "name": "Tropocollagen", "formula": "X", "compartment": "c", "id": "tropcollg_rest_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -1, "name": "3-mercaptolactate-cysteine disulfide", "formula": "C6H10O5S2N", "compartment": "c", "id": "mercplaccys_c", "annotation": {"bigg.metabolite": "mercplaccys", "sbo": "SBO:0000247"}}, {"charge": 0, "name": "Propionyl-carnitine", "formula": "C10H19NO4", "compartment": "c", "id": "pcrn_c", "annotation": {"bigg.metabolite": "pcrn", "sbo": "SBO:0000247"}}, {"charge": 1, "name": "Procollagen L-lysine (to be modified)", "formula": "XH", "compartment": "c", "id": "pcollglys_c", "annotation": {"bigg.metabolite": "pcollglys", "sbo": "SBO:0000247"}}, {"charge": 0, "name": "Procollagen (modified protein)", "formula": "X", "compartment": "c", "id": "pcollg_mod_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 0, "name": "Procollagen (unmodified portion)", "formula": "X", "compartment": "c", "id": "pcollg_rest_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 0, "name": "Procollagen (trimerized)", "formula": "X", "compartment": "c", "id": "pcollg_tri_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 0, "name": "Procollagen (with di-Sulfide bridges for registration)", "formula": "X", "compartment": "c", "id": "pcollg_diS_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -3, "name": "Dehydrodolichol diphosphate, n=18", "formula": "C110H177O7P2", "compartment": "c", "id": "dedoldp_c", "annotation": {"bigg.metabolite": ["dedoldp_L", "dedoldp_U"], "sbo": "SBO:0000247", "kegg.compound": "C05859"}}, {"charge": -1, "name": "2-Hydroxyphenylacetate", "formula": "C8H7O3", "compartment": "c", "id": "2hyoxplac_c", "annotation": {"bigg.metabolite": "2hyoxplac", "sbo": "SBO:0000247", "kegg.compound": "C05852"}}, {"charge": -1, "name": "Phosphatidylserine", "formula": "C43.1308H74.1556N1.0O10.0P1.0", "compartment": "c", "id": "ps_c", "annotation": {"bigg.metabolite": ["ps181", "ps180", "ps161", "ps160", "ps141", "ps140", "ps120", "ps_SA", "ps_hs", "ps_EC", "ps_HP", "ps_SC"], "sbo": "SBO:0000247", "kegg.compound": "C02737"}}, {"charge": 1, "name": "L-Selenocysteinyl-tRNA(Sec)", "formula": "C3H7NO2SeR", "compartment": "c", "id": "sectrna_c", "annotation": {"bigg.metabolite": "sectrna", "sbo": "SBO:0000247", "kegg.compound": "C06482"}}, {"charge": 0, "name": "L-Glutamyl-tRNA(Glu)", "formula": "C5H8NO4R", "compartment": "m", "id": "glutrna_m", "annotation": {"bigg.metabolite": "glutrna", "sbo": "SBO:0000247", "kegg.compound": "C02987"}}, {"charge": 0, "name": "L-Aspartyl-tRNA(Asp)", "formula": "C4H6NO4R", "compartment": "m", "id": "asptrna_m", "annotation": {"bigg.metabolite": "asptrna", "sbo": "SBO:0000247", "kegg.compound": "C02984"}}, {"charge": 1, "name": "L-Histidyl-tRNA(His)", "formula": "C6H9N3O2R", "compartment": "m", "id": "histrna_m", "annotation": {"bigg.metabolite": "histrna", "sbo": "SBO:0000247", "kegg.compound": "C02988"}}, {"charge": -1, "name": "(S)-3-Hydroxybutanoate", "formula": "C4H7O3", "compartment": "c", "id": "S3hb_c", "annotation": {"bigg.metabolite": "bhb", "sbo": "SBO:0000247", "kegg.compound": "C03197"}}, {"charge": -4, "name": "Isovaleryl-CoA", "formula": "C26H40N7O17P3S", "compartment": "c", "id": "ivcoa_c", "annotation": {"bigg.metabolite": "ivcoa", "sbo": "SBO:0000247", "kegg.compound": "C02939"}}, {"charge": -1, "name": "7alpha-Hydroxy-3-oxo-4-cholestenoate", "formula": "C27H41O4", "compartment": "m", "id": "7a3o4chlstnt_m", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C17337"}}, {"charge": 0, "name": "\"7alpha,12alpha-Dihydroxycholest-4-en-3-one\"", "formula": "C27H44O3", "compartment": "m", "id": "xoldiolone_m", "annotation": {"bigg.metabolite": "xoldiolone", "sbo": "SBO:0000247", "kegg.compound": "C17339"}}, {"charge": 1, "name": "L-Phenylalanyl-tRNA(Phe)", "formula": "C9H11NO2R", "compartment": "c", "id": "phetrna_c", "annotation": {"bigg.metabolite": "phetrna", "sbo": "SBO:0000247", "kegg.compound": "C03511"}}, {"charge": 1, "name": "L-Tryptophanyl-tRNA(Trp)", "formula": "C11H12N2O2R", "compartment": "c", "id": "trptrna_c", "annotation": {"bigg.metabolite": "trptrna", "sbo": "SBO:0000247", "kegg.compound": "C03512"}}, {"charge": -1, "name": "R total 7", "formula": "C18.0H35.0O2.0", "compartment": "c", "id": "Rtotal7_c", "annotation": {"bigg.metabolite": ["Rtotal", "Rtotal2", "Rtotal3"], "sbo": "SBO:0000247"}}, {"charge": 0, "name": "L-3-Amino-isobutanoate", "formula": "C4H9NO2", "compartment": "c", "id": "3aib_c", "annotation": {"bigg.metabolite": "3aib", "sbo": "SBO:0000247", "kegg.compound": "C03284"}}, {"charge": -1, "name": "(R)-Mevalonate", "formula": "C6H11O4", "compartment": "c", "id": "mev-R_c", "annotation": {"bigg.metabolite": "mev-R", "sbo": "SBO:0000247", "kegg.compound": "C00418"}}, {"charge": -2, "name": "\"7,8-Dihydrofolate\"", "formula": "C19H19N7O6", "compartment": "c", "id": "dhf_c", "annotation": {"bigg.metabolite": "dhf", "sbo": "SBO:0000247", "kegg.compound": "C00415"}}, {"charge": -2, "name": "Phosphatidic acid (phospholipids)", "formula": "C40.1308H68.1556O8.0P1.0", "compartment": "c", "id": "pa_pl_c", "annotation": {"bigg.metabolite": ["pa_hs", "pa_Hp"], "sbo": "SBO:0000247", "kegg.compound": "C00416"}}, {"charge": -1, "name": "3-Dehydro-L-gulonate", "formula": "C6H9O7", "compartment": "c", "id": "3dhguln_c", "annotation": {"bigg.metabolite": "3dhguln", "sbo": "SBO:0000247", "kegg.compound": "C00618"}}, {"charge": -4, "name": "Stearoyl-CoA (n-C18:0CoA)", "formula": "C39H66N7O17P3S", "compartment": "c", "id": "stcoa_c", "annotation": {"bigg.metabolite": "stcoa", "sbo": "SBO:0000247", "kegg.compound": "C00412"}}, {"charge": -1, "name": "Dolichyl phosphate D-mannose", "formula": "C116H190O9P", "compartment": "c", "id": "dolmanp_c", "annotation": {"bigg.metabolite": "dolmanp", "sbo": "SBO:0000247", "kegg.compound": "C03862"}}, {"charge": 1, "name": "trimethylamine", "formula": "C3H10N", "compartment": "c", "id": "tma_c", "annotation": {"bigg.metabolite": "tma", "sbo": "SBO:0000247", "kegg.compound": "C00565"}}, {"charge": -3, "name": "3-Phospho-D-glycerate", "formula": "C3H4O7P", "compartment": "e", "id": "3pg_e", "annotation": {"bigg.metabolite": "3pg", "sbo": "SBO:0000247", "kegg.compound": "C00197"}}, {"charge": -3, "name": "Geranyl diphosphate", "formula": "C10H17O7P2", "compartment": "c", "id": "grdp_c", "annotation": {"bigg.metabolite": "grdp", "sbo": "SBO:0000247", "kegg.compound": "C00341"}}, {"charge": 0, "name": "Reduced thioredoxin", "formula": "XH2", "compartment": "c", "id": "trdrd_c", "annotation": {"bigg.metabolite": "trdrd", "sbo": "SBO:0000247", "kegg.compound": "C00342"}}, {"charge": 0, "name": "Oxidized thioredoxin", "formula": "X", "compartment": "c", "id": "trdox_c", "annotation": {"bigg.metabolite": "trdox", "sbo": "SBO:0000247", "kegg.compound": "C00343"}}, {"charge": -1, "name": "phosphatidylglycerol ", "formula": "C43.1308H75.1556O10.0P1.0", "compartment": "c", "id": "pglyc_c", "annotation": {"bigg.metabolite": "pglyc_hs", "sbo": "SBO:0000247", "kegg.compound": "C00344"}}, {"charge": -3, "name": "6-Phospho-D-gluconate", "formula": "C6H10O10P", "compartment": "c", "id": "6pgc_c", "annotation": {"bigg.metabolite": "6pgc", "sbo": "SBO:0000247", "kegg.compound": "C00345"}}, {"charge": -1, "name": "D-Glucuronate", "formula": "C6H9O7", "compartment": "e", "id": "glcur_e", "annotation": {"bigg.metabolite": "glcur", "sbo": "SBO:0000247", "kegg.compound": "C00191"}}, {"charge": -3, "name": "GDP", "formula": "C10H12N5O11P2", "compartment": "m", "id": "gdp_m", "annotation": {"bigg.metabolite": "gdp", "sbo": "SBO:0000247", "kegg.compound": "C00035"}}, {"charge": 0, "name": "Ubiquinone-8", "formula": "C49H74O4", "compartment": "e", "id": "q8_e", "annotation": {"bigg.metabolite": "q8", "sbo": "SBO:0000247"}}, {"charge": 0, "name": "Glycine", "formula": "C2H5NO2", "compartment": "m", "id": "gly_m", "annotation": {"bigg.metabolite": "gly", "sbo": "SBO:0000247", "kegg.compound": "C00037"}}, {"charge": 0, "name": "Protoheme", "formula": "C34H30FeN4O4", "compartment": "m", "id": "pheme_m", "annotation": {"bigg.metabolite": "pheme", "sbo": "SBO:0000247", "kegg.compound": "C00032"}}, {"charge": -1, "name": "Acetate", "formula": "C2H3O2", "compartment": "m", "id": "ac_m", "annotation": {"bigg.metabolite": "ac", "sbo": "SBO:0000247", "kegg.compound": "C00033"}}, {"charge": -2, "name": "5-Amino-1-(5-Phospho-D-ribosyl)imidazole-4-carboxamide", "formula": "C9H13N4O8P", "compartment": "c", "id": "aicar_c", "annotation": {"bigg.metabolite": "aicar", "sbo": "SBO:0000247", "kegg.compound": "C04677"}}, {"charge": -3, "name": "2-Phosphoglycolate", "formula": "C2H2O6P", "compartment": "c", "id": "2pglyc_c", "annotation": {"bigg.metabolite": "2pglyc", "sbo": "SBO:0000247", "kegg.compound": "C00988"}}, {"charge": 0, "name": "Tetrahydrobiopterin-4a-carbinolamine", "formula": "C9H15N5O4", "compartment": "c", "id": "thbpt4acam_c", "annotation": {"bigg.metabolite": "thbpt4acam", "sbo": "SBO:0000247", "kegg.compound": "C15522"}}, {"charge": 0, "name": "\"7-alpha,25-Dihydroxycholesterol\"", "formula": "C27H46O3", "compartment": "c", "id": "xoltri25_c", "annotation": {"bigg.metabolite": "xoltri25", "sbo": "SBO:0000247", "kegg.compound": "C15520"}}, {"charge": 0, "name": "L-Isoleucine", "formula": "C6H13NO2", "compartment": "m", "id": "ile-L_m", "annotation": {"bigg.metabolite": "ile-L", "sbo": "SBO:0000247", "kegg.compound": "C00407"}}, {"charge": -1, "name": "2-Oxobutanoate", "formula": "C4H5O3", "compartment": "m", "id": "2obut_m", "annotation": {"bigg.metabolite": "2obut", "sbo": "SBO:0000247", "kegg.compound": "C00109"}}, {"charge": -4, "name": "Propanoyl-CoA", "formula": "C24H36N7O17P3S", "compartment": "m", "id": "ppcoa_m", "annotation": {"bigg.metabolite": "ppcoa", "sbo": "SBO:0000247", "kegg.compound": "C00100"}}, {"charge": -2, "name": "\"5,6,7,8-Tetrahydrofolate\"", "formula": "C19H21N7O6", "compartment": "m", "id": "thf_m", "annotation": {"bigg.metabolite": "thf", "sbo": "SBO:0000247", "kegg.compound": "C00101"}}, {"charge": 0, "name": "Deoxyribose", "formula": "C5H10O4", "compartment": "e", "id": "drib_e", "annotation": {"bigg.metabolite": "drib", "sbo": "SBO:0000247", "kegg.compound": "C01801"}}, {"charge": 1, "name": "L-Lysine", "formula": "C6H15N2O2", "compartment": "e", "id": "lys-L_e", "annotation": {"bigg.metabolite": "lys-L", "sbo": "SBO:0000247", "kegg.compound": "C00047"}}, {"charge": 0, "name": "L-Alanine", "formula": "C3H7NO2", "compartment": "e", "id": "ala-L_e", "annotation": {"bigg.metabolite": "ala-L", "sbo": "SBO:0000247", "kegg.compound": "C00041"}}, {"charge": -2, "name": "Succinate", "formula": "C4H4O4", "compartment": "e", "id": "succ_e", "annotation": {"bigg.metabolite": "succ", "sbo": "SBO:0000247", "kegg.compound": "C00042"}}, {"charge": 0, "name": "Taurine", "formula": "C2H7NO3S", "compartment": "e", "id": "taur_e", "annotation": {"bigg.metabolite": "taur", "sbo": "SBO:0000247", "kegg.compound": "C00245"}}, {"charge": -1, "name": "L-Aspartate", "formula": "C4H6NO4", "compartment": "e", "id": "asp-L_e", "annotation": {"bigg.metabolite": "asp-L", "sbo": "SBO:0000247", "kegg.compound": "C00049"}}, {"charge": -1, "name": "Glyoxylate", "formula": "C2H1O3", "compartment": "e", "id": "glx_e", "annotation": {"bigg.metabolite": "glx", "sbo": "SBO:0000247", "kegg.compound": "C00048"}}, {"charge": 0, "name": "L-Threonine", "formula": "C4H9NO3", "compartment": "c", "id": "thr-L_c", "annotation": {"bigg.metabolite": "thr-L", "sbo": "SBO:0000247", "kegg.compound": "C00188"}}, {"charge": 1, "name": "Ethanolamine", "formula": "C2H8NO", "compartment": "c", "id": "etha_c", "annotation": {"bigg.metabolite": "etha", "sbo": "SBO:0000247", "kegg.compound": "C00189"}}, {"charge": -1, "name": "L-Lactate", "formula": "C3H5O3", "compartment": "c", "id": "lac-L_c", "annotation": {"bigg.metabolite": "lac-L", "sbo": "SBO:0000247", "kegg.compound": "C00186"}}, {"charge": 0, "name": "Cholesterol", "formula": "C27H46O", "compartment": "c", "id": "chsterol_c", "annotation": {"bigg.metabolite": "chsterol", "sbo": "SBO:0000247", "kegg.compound": "C00187"}}, {"charge": 0, "name": "Dihydroxyacetone", "formula": "C3H6O3", "compartment": "c", "id": "dha_c", "annotation": {"bigg.metabolite": "dha", "sbo": "SBO:0000247", "kegg.compound": "C00184"}}, {"charge": 0, "name": "Cellobiose", "formula": "C12H22O11", "compartment": "c", "id": "clb_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C00185"}}, {"charge": 0, "name": "glycogen", "formula": "C6H10O5", "compartment": "c", "id": "glycogen_c", "annotation": {"bigg.metabolite": "glycogen", "sbo": "SBO:0000247", "kegg.compound": "C00182"}}, {"charge": 0, "name": "L-Valine", "formula": "C5H11NO2", "compartment": "c", "id": "val-L_c", "annotation": {"bigg.metabolite": "val-L", "sbo": "SBO:0000247", "kegg.compound": "C00183"}}, {"charge": 0, "name": "D-Xylose", "formula": "C5H10O5", "compartment": "c", "id": "xyl-D_c", "annotation": {"bigg.metabolite": "xyl-D", "sbo": "SBO:0000247", "kegg.compound": "C00181"}}, {"charge": 0, "name": "Nicotinamide", "formula": "C6H6N2O", "compartment": "e", "id": "ncam_e", "annotation": {"bigg.metabolite": "ncam", "sbo": "SBO:0000247", "kegg.compound": "C00153"}}, {"charge": 0, "name": "Thymidine", "formula": "C10H14N2O5", "compartment": "m", "id": "thymd_m", "annotation": {"bigg.metabolite": "thymd", "sbo": "SBO:0000247", "kegg.compound": "C00214"}}, {"charge": -1, "name": "3-4-Dihydroxyphenylacetate", "formula": "C8H7O4", "compartment": "c", "id": "34dhpha_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C01161"}}, {"charge": -3, "name": "dUDP", "formula": "C9H11N2O11P2", "compartment": "m", "id": "dudp_m", "annotation": {"bigg.metabolite": "dudp", "sbo": "SBO:0000247", "kegg.compound": "C01346"}}, {"charge": -1, "name": "2-Amino-3-carboxymuconate semialdehyde", "formula": "C7H6NO5", "compartment": "c", "id": "cmusa_c", "annotation": {"bigg.metabolite": "cmusa", "sbo": "SBO:0000247", "kegg.compound": "C04409"}}, {"charge": -2, "name": "Pseudouridine 5'-phosphate", "formula": "C9H11N2O9P", "compartment": "c", "id": "psd5p_c", "annotation": {"bigg.metabolite": "psd5p", "sbo": "SBO:0000247", "kegg.compound": "C01168"}}, {"charge": 0, "name": "L-Asparagine", "formula": "C4H8N2O3", "compartment": "e", "id": "asn-L_e", "annotation": {"bigg.metabolite": "asn-L", "sbo": "SBO:0000247", "kegg.compound": "C00152"}}, {"charge": -1, "name": "3-Ureidoisobutyrate", "formula": "C5H9N2O3", "compartment": "c", "id": "3uib_c", "annotation": {"bigg.metabolite": "3uib", "sbo": "SBO:0000247", "kegg.compound": "C05100"}}, {"charge": -6, "name": "pentaglutamyl folate (THF)", "formula": "C39H45N11O18", "compartment": "c", "id": "5thf_c", "annotation": {"bigg.metabolite": "5thf", "sbo": "SBO:0000247"}}, {"charge": -8, "name": "heptaglutamyl folate (THF)", "formula": "C49H57N13O24", "compartment": "c", "id": "7thf_c", "annotation": {"bigg.metabolite": "7thf", "sbo": "SBO:0000247"}}, {"charge": -1, "name": "R total 2 position", "formula": "C18.5654H31.5778O2.0", "compartment": "c", "id": "Rtotal2_c", "annotation": {"bigg.metabolite": ["Rtotal", "Rtotal2", "Rtotal3"], "sbo": "SBO:0000247"}}, {"charge": -4, "name": "R total 2 coenzyme A", "formula": "C39.5654H62.5778N7.0O17.0P3.0S1.0", "compartment": "c", "id": "Rtotal2coa_c", "annotation": {"bigg.metabolite": ["Rtotalcoa", "Rtotal2coa", "Rtotal3coa", "acoa"], "sbo": "SBO:0000247"}}, {"charge": -4, "name": "R total 3 Coenzyme A", "formula": "C38.3018H62.5094N7.0O17.0P3.0S1.0", "compartment": "c", "id": "Rtotal3coa_c", "annotation": {"bigg.metabolite": ["Rtotalcoa", "Rtotal2coa", "Rtotal3coa", "acoa"], "sbo": "SBO:0000247"}}, {"charge": -1, "name": "NMN", "formula": "C11H14N2O8P", "compartment": "e", "id": "nmn_e", "annotation": {"bigg.metabolite": "nmn", "sbo": "SBO:0000247", "kegg.compound": "C00455"}}, {"charge": -3, "name": "Orotidine 5'-phosphate", "formula": "C10H10N2O11P", "compartment": "e", "id": "orot5p_e", "annotation": {"bigg.metabolite": "orot5p", "sbo": "SBO:0000247", "kegg.compound": "C01103"}}, {"charge": -4, "name": "dTTP", "formula": "C10H13N2O14P3", "compartment": "e", "id": "dttp_e", "annotation": {"bigg.metabolite": "dttp", "sbo": "SBO:0000247", "kegg.compound": "C00459"}}, {"charge": 0, "name": "Inosine", "formula": "C10H12N4O5", "compartment": "e", "id": "ins_e", "annotation": {"bigg.metabolite": "ins", "sbo": "SBO:0000247", "kegg.compound": "C00294"}}, {"charge": -1, "name": "Orotate", "formula": "C5H3N2O4", "compartment": "e", "id": "orot_e", "annotation": {"bigg.metabolite": "orot", "sbo": "SBO:0000247", "kegg.compound": "C00295"}}, {"charge": 0, "name": "Xanthosine", "formula": "C10H12N4O6", "compartment": "c", "id": "xtsn_c", "annotation": {"bigg.metabolite": "xtsn", "sbo": "SBO:0000247", "kegg.compound": "C01762"}}, {"charge": 0, "name": "Uridine", "formula": "C9H12N2O6", "compartment": "e", "id": "uri_e", "annotation": {"bigg.metabolite": "uri", "sbo": "SBO:0000247", "kegg.compound": "C00299"}}, {"charge": -4, "name": "3-Oxohexadecanoyl-CoA", "formula": "C37H60N7O18P3S", "compartment": "m", "id": "3ohdcoa_m", "annotation": {"bigg.metabolite": "3ohdcoa", "sbo": "SBO:0000247", "kegg.compound": "C05259"}}, {"charge": -4, "name": "(S)-3-Hydroxyhexadecanoyl-CoA", "formula": "C37H62N7O18P3S", "compartment": "m", "id": "3hhdcoa_m", "annotation": {"bigg.metabolite": "3hhdcoa", "sbo": "SBO:0000247", "kegg.compound": "C05258"}}, {"charge": -2, "name": "Quinolinate", "formula": "C7H3NO4", "compartment": "c", "id": "quln_c", "annotation": {"bigg.metabolite": "quln", "sbo": "SBO:0000247", "kegg.compound": "C03722"}}, {"charge": -1, "name": "Ascaroside 7", "formula": "C13H21O6", "compartment": "c", "id": "ascr7_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -4, "name": "27-ascaryl-heptacosanoic acyl coa", "formula": "C54H94N7O21P3S", "compartment": "c", "id": "27ascfa27p0coa_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -4, "name": "ascaryl (ascr18) coa", "formula": "C38H62N7O21P3S", "compartment": "c", "id": "ascr18coa_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -4, "name": "ascaryl (ascr10) coa", "formula": "C36H58N7O21P3S", "compartment": "c", "id": "ascr10coa_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -4, "name": "ascaryl (ascr1) coa", "formula": "C34H54N7O21P3S", "compartment": "c", "id": "ascr1coa_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 0, "name": "Fatty acyl (C17:iso) carnitine", "formula": "C24H47NO4", "compartment": "m", "id": "fa17p0isocrn_m", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 0, "name": "Fatty acyl (C9:iso) carnitine", "formula": "C16H31NO4", "compartment": "m", "id": "fa9p0isocrn_m", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 0, "name": "Mitochondrial protein", "formula": "C4.8102H7.6357N1.3358O1.4603S0.0291", "compartment": "m", "id": "prot_mito_m", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 0, "name": "cis-3,4-methylenedecanoyl coa", "formula": "C18H33NO4", "compartment": "m", "id": "fa11c3crn_m", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 0, "name": "cis-9,10-methylenehexadecanoyl carnitine", "formula": "C24H45NO4", "compartment": "m", "id": "fa17c9crn_m", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 0, "name": "cis-11,12-methyleneoctadecanoyl carnitine", "formula": "C26H49NO4", "compartment": "m", "id": "fa19c11crn_m", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 0, "name": "Fatty acyl (C15:iso) carnitine", "formula": "C22H43NO4", "compartment": "m", "id": "fa15p0isocrn_m", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -3, "name": "dUDP", "formula": "C9H11N2O11P2", "compartment": "c", "id": "dudp_c", "annotation": {"bigg.metabolite": "dudp", "sbo": "SBO:0000247", "kegg.compound": "C01346"}}, {"charge": 0, "name": "Stachyose", "formula": "C24H42O21", "compartment": "c", "id": "stachyose_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C01613"}}, {"charge": 1, "name": "L-Tyrosyl-tRNA(Tyr)", "formula": "C9H11NO3R", "compartment": "c", "id": "tyrtrna_c", "annotation": {"bigg.metabolite": "tyrtrna", "sbo": "SBO:0000247", "kegg.compound": "C02839"}}, {"charge": -1, "name": "3-Methylimidazoleacetic acid", "formula": "C6H7N2O2", "compartment": "c", "id": "3mlda_c", "annotation": {"bigg.metabolite": "3mlda", "sbo": "SBO:0000247", "kegg.compound": "C05828"}}, {"charge": -4, "name": "Dodecanoyl-CoA (n-C12:0CoA)", "formula": "C33H54N7O17P3S", "compartment": "c", "id": "ddcacoa_c", "annotation": {"bigg.metabolite": "ddcacoa", "sbo": "SBO:0000247", "kegg.compound": "C01832"}}, {"charge": -1, "name": "3-Mercaptolactate", "formula": "C3H5O3S", "compartment": "c", "id": "mercplac_c", "annotation": {"bigg.metabolite": "mercplac", "sbo": "SBO:0000247", "kegg.compound": "C05823"}}, {"charge": -4, "name": "3'-Phosphoadenylyl sulfate", "formula": "C10H11N5O13P2S", "compartment": "c", "id": "paps_c", "annotation": {"bigg.metabolite": "paps", "sbo": "SBO:0000247", "kegg.compound": "C00053"}}, {"charge": 0, "name": "3-Methylimidazole acetaldehyde", "formula": "C6H8N2O", "compartment": "c", "id": "3mldz_c", "annotation": {"bigg.metabolite": "3mldz", "sbo": "SBO:0000247", "kegg.compound": "C05827"}}, {"charge": -4, "name": "stearidonyl coenzyme A", "formula": "C39H58N7O17P3S", "compartment": "c", "id": "strdnccoa_c", "annotation": {"bigg.metabolite": "strdnccoa", "sbo": "SBO:0000247", "kegg.compound": "C16163"}}, {"charge": -4, "name": "alpha-Linolenoyl-CoA", "formula": "C39H60N7O17P3S", "compartment": "c", "id": "lnlncacoa_c", "annotation": {"bigg.metabolite": "lnlncacoa", "sbo": "SBO:0000247", "kegg.compound": "C16162"}}, {"charge": -4, "name": "timnodonyl coenzyme A", "formula": "C41H60N7O17P3S", "compartment": "c", "id": "tmndnccoa_c", "annotation": {"bigg.metabolite": "tmndnccoa", "sbo": "SBO:0000247", "kegg.compound": "C16165"}}, {"charge": -4, "name": "eicosatetranoyl coenzyme A", "formula": "C41H62N7O17P3S", "compartment": "c", "id": "eicostetcoa_c", "annotation": {"bigg.metabolite": "eicostetcoa", "sbo": "SBO:0000247", "kegg.compound": "C16164"}}, {"charge": -4, "name": "Vaccenyl coenzyme A", "formula": "C39H64N7O17P3S", "compartment": "m", "id": "vacccoa_m", "annotation": {"bigg.metabolite": "vacccoa", "sbo": "SBO:0000247"}}, {"charge": 0, "name": "L-Palmitoylcarnitine", "formula": "C23H45NO4", "compartment": "m", "id": "pmtcrn_m", "annotation": {"bigg.metabolite": "pmtcrn", "sbo": "SBO:0000247", "kegg.compound": "C02990"}}, {"charge": 1, "name": "L-Threonyl-tRNA(Thr)", "formula": "C4H9NO3R", "compartment": "m", "id": "thrtrna_m", "annotation": {"bigg.metabolite": "thrtrna", "sbo": "SBO:0000247", "kegg.compound": "C02992"}}, {"charge": 0, "name": "Retinyl palminate", "formula": "C36H60O2", "compartment": "c", "id": "retpalm_c", "annotation": {"bigg.metabolite": "retpalm", "sbo": "SBO:0000247", "kegg.compound": "C02588"}}, {"charge": 0, "name": "tetradecanoyl carnitine", "formula": "C21H41NO4", "compartment": "m", "id": "ttdcrn_m", "annotation": {"bigg.metabolite": "ttdcrn", "sbo": "SBO:0000247"}}, {"charge": 0, "name": "sn-Glycero-3-phosphocholine", "formula": "C8H20NO6P", "compartment": "e", "id": "g3pc_e", "annotation": {"bigg.metabolite": "g3pc", "sbo": "SBO:0000247", "kegg.compound": "C00670"}}, {"charge": -1, "name": "(S)-3-Methyl-2-oxopentanoate", "formula": "C6H9O3", "compartment": "e", "id": "3mop_e", "annotation": {"bigg.metabolite": "3mop", "sbo": "SBO:0000247", "kegg.compound": "C00671"}}, {"charge": -4, "name": "Palmitoleyl-coA", "formula": "C37H60N7O17P3S", "compartment": "m", "id": "fa16p1n7coa_m", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -1, "name": "3-Methylimidazoleacetic acid", "formula": "C6H7N2O2", "compartment": "e", "id": "3mlda_e", "annotation": {"bigg.metabolite": "3mlda", "sbo": "SBO:0000247", "kegg.compound": "C05828"}}, {"charge": -1, "name": "Superoxide anion", "formula": "O2", "compartment": "e", "id": "o2s_e", "annotation": {"bigg.metabolite": "o2s", "sbo": "SBO:0000247", "kegg.compound": "C00704"}}, {"charge": -4, "name": "linoleic coenzyme A", "formula": "C39H62N7O17P3S", "compartment": "c", "id": "lnlccoa_c", "annotation": {"bigg.metabolite": "lnlccoa", "sbo": "SBO:0000247", "kegg.compound": "C02050"}}, {"charge": -5, "name": "(S)-Methylmalonyl-CoA", "formula": "C25H35N7O19P3S", "compartment": "m", "id": "mmcoa-S_m", "annotation": {"bigg.metabolite": "mmcoa-S", "sbo": "SBO:0000247", "kegg.compound": "C00683"}}, {"charge": -1, "name": "Iodide", "formula": "I", "compartment": "e", "id": "i_e", "annotation": {"bigg.metabolite": "i", "sbo": "SBO:0000247", "kegg.compound": "C00708"}}, {"charge": 0, "name": "5-Hydroxy-L-tryptophan", "formula": "C11H12N2O3", "compartment": "e", "id": "5htrp_e", "annotation": {"bigg.metabolite": "5htrp", "sbo": "SBO:0000247", "kegg.compound": "C00643"}}, {"charge": 1, "name": "Aminoacetone", "formula": "C3H8NO", "compartment": "m", "id": "aact_m", "annotation": {"bigg.metabolite": "aact", "sbo": "SBO:0000247", "kegg.compound": "C01888"}}, {"charge": -1, "name": "4-Hydroxyphenylacetate", "formula": "C8H7O3", "compartment": "e", "id": "4hphac_e", "annotation": {"bigg.metabolite": "4hphac", "sbo": "SBO:0000247", "kegg.compound": "C00642"}}, {"charge": -1, "name": "Cob(I)alamin", "formula": "C62H88CoN13O14P", "compartment": "e", "id": "cbl1_e", "annotation": {"bigg.metabolite": "cbl1", "sbo": "SBO:0000247", "kegg.compound": "C00853"}}, {"charge": -2, "name": "(S)-2-Hydroxyglutarate", "formula": "C5H6O5", "compartment": "e", "id": "2hglut_e", "annotation": {"bigg.metabolite": "S2hglut", "sbo": "SBO:0000247", "kegg.compound": "C02630"}}, {"charge": 0, "name": "O-Acetyl-L-serine", "formula": "C5H9NO4", "compartment": "c", "id": "acser_c", "annotation": {"bigg.metabolite": "acser", "sbo": "SBO:0000247", "kegg.compound": "C00979"}}, {"charge": -3, "name": "Molybdopterin", "formula": "C10H11N5O6PS2", "compartment": "c", "id": "molybd_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C05924"}}, {"charge": 0, "name": "D-glucosaminylphosphatidylinositol", "formula": "C52.1308H91.1556N1.0O17.0P1.0", "compartment": "c", "id": "gpail_c", "annotation": {"bigg.metabolite": "gpail_hs", "sbo": "SBO:0000247", "kegg.compound": "C04248"}}, {"charge": -2, "name": "Quinolinate", "formula": "C7H3NO4", "compartment": "e", "id": "quln_e", "annotation": {"bigg.metabolite": "quln", "sbo": "SBO:0000247", "kegg.compound": "C03722"}}, {"charge": -1, "name": "D-Aspartate", "formula": "C4H6NO4", "compartment": "c", "id": "asp-D_c", "annotation": {"bigg.metabolite": "asp-D", "sbo": "SBO:0000247", "kegg.compound": "C00402"}}, {"charge": 0, "name": "L-Isoleucine", "formula": "C6H13NO2", "compartment": "c", "id": "ile-L_c", "annotation": {"bigg.metabolite": "ile-L", "sbo": "SBO:0000247", "kegg.compound": "C00407"}}, {"charge": -2, "name": "5-Formyltetrahydrofolate", "formula": "C20H21N7O7", "compartment": "c", "id": "5fthf_c", "annotation": {"bigg.metabolite": "5fthf", "sbo": "SBO:0000247", "kegg.compound": "C03479"}}, {"charge": -1, "name": "arachidonic acid", "formula": "C20H31O2", "compartment": "e", "id": "arachd_e", "annotation": {"bigg.metabolite": "arachd", "sbo": "SBO:0000247", "kegg.compound": "C00219"}}, {"charge": 0, "name": "\"3alpha,7alpha,12alpha,26-Tetrahydroxy-5beta-cholestane\"", "formula": "C27H48O4", "compartment": "c", "id": "xoltetrol_c", "annotation": {"bigg.metabolite": "xoltetrol", "sbo": "SBO:0000247", "kegg.compound": "C05446"}}, {"charge": 0, "name": "Dihydroneopterin", "formula": "C9H13N5O4", "compartment": "m", "id": "dhnpt_m", "annotation": {"bigg.metabolite": "dhnpt", "sbo": "SBO:0000247", "kegg.compound": "C04874"}}, {"charge": 0, "name": "D-Glyceraldehyde", "formula": "C3H6O3", "compartment": "c", "id": "glyald_c", "annotation": {"bigg.metabolite": "glyald", "sbo": "SBO:0000247", "kegg.compound": "C00577"}}, {"charge": -1, "name": "cAMP", "formula": "C10H11N5O6P", "compartment": "c", "id": "camp_c", "annotation": {"bigg.metabolite": "camp", "sbo": "SBO:0000247", "kegg.compound": "C00575"}}, {"charge": -1, "name": "CDPethanolamine", "formula": "C11H19N4O11P2", "compartment": "c", "id": "cdpea_c", "annotation": {"bigg.metabolite": "cdpea", "sbo": "SBO:0000247", "kegg.compound": "C00570"}}, {"charge": -4, "name": "linoleic coenzyme A", "formula": "C39H62N7O17P3S", "compartment": "m", "id": "lnlccoa_m", "annotation": {"bigg.metabolite": "lnlccoa", "sbo": "SBO:0000247", "kegg.compound": "C02050"}}, {"charge": 0, "name": "Lipoylprotein", "formula": "S2X", "compartment": "m", "id": "lpro_m", "annotation": {"bigg.metabolite": "lpro", "sbo": "SBO:0000247", "kegg.compound": "C02051"}}, {"charge": -2, "name": "N-Acetyl-D-glucosamine 6-phosphate", "formula": "C8H14NO9P", "compartment": "c", "id": "acgam6p_c", "annotation": {"bigg.metabolite": "acgam6p", "sbo": "SBO:0000247", "kegg.compound": "C00357"}}, {"charge": -1, "name": "Pyruvate", "formula": "C3H3O3", "compartment": "m", "id": "pyr_m", "annotation": {"bigg.metabolite": "pyr", "sbo": "SBO:0000247", "kegg.compound": "C00022"}}, {"charge": 0, "name": "S-Adenosyl-L-homocysteine", "formula": "C14H20N6O5S", "compartment": "m", "id": "ahcys_m", "annotation": {"bigg.metabolite": "ahcys", "sbo": "SBO:0000247", "kegg.compound": "C00021"}}, {"charge": -4, "name": "\"D-Fructose 1,6-bisphosphate\"", "formula": "C6H10O12P2", "compartment": "c", "id": "fdp_c", "annotation": {"bigg.metabolite": "fdp", "sbo": "SBO:0000247", "kegg.compound": "C00354"}}, {"charge": 0, "name": "Hydrogen peroxide", "formula": "H2O2", "compartment": "m", "id": "h2o2_m", "annotation": {"bigg.metabolite": "h2o2", "sbo": "SBO:0000247", "kegg.compound": "C00027"}}, {"charge": -1, "name": "D-Glucosamine 6-phosphate", "formula": "C6H13NO8P", "compartment": "c", "id": "gam6p_c", "annotation": {"bigg.metabolite": "gam6p", "sbo": "SBO:0000247", "kegg.compound": "C00352"}}, {"charge": -1, "name": "L-Glutamate", "formula": "C5H8NO4", "compartment": "m", "id": "glu-L_m", "annotation": {"bigg.metabolite": "glu-L", "sbo": "SBO:0000247", "kegg.compound": "C00025"}}, {"charge": 0, "name": "Phosphatidylethanolamine", "formula": "C42.1308H75.1556N1.0O8.0P1.0", "compartment": "c", "id": "pe_c", "annotation": {"bigg.metabolite": ["pe181", "pe180", "pe161", "pe160", "pe141", "pe140", "pe120", "pe_SA", "pe_hs", "pe_EC", "pe_HP", "pe_SC"], "sbo": "SBO:0000247", "kegg.compound": "C00350"}}, {"charge": 0, "name": "Androsterone", "formula": "C19H30O2", "compartment": "e", "id": "andrstrn_e", "annotation": {"bigg.metabolite": "andrstrn", "sbo": "SBO:0000247", "kegg.compound": "C00523"}}, {"charge": 1, "name": "1-Methylnicotinamide", "formula": "C7H9N2O", "compartment": "e", "id": "1mncam_e", "annotation": {"bigg.metabolite": "1mncam", "sbo": "SBO:0000247", "kegg.compound": "C02918"}}, {"charge": 4, "name": "Spermine", "formula": "C10H30N4", "compartment": "c", "id": "sprm_c", "annotation": {"bigg.metabolite": "sprm", "sbo": "SBO:0000247", "kegg.compound": "C00750"}}, {"charge": 0, "name": "Ferricytochrome b5", "formula": "X", "compartment": "c", "id": "ficytb_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C00996"}}, {"charge": 0, "name": "Ferrocytochrome b5", "formula": "XH", "compartment": "c", "id": "focytb_c", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C00999"}}, {"charge": 0, "name": "Glycerol", "formula": "C3H8O3", "compartment": "m", "id": "glyc_m", "annotation": {"bigg.metabolite": "glyc", "sbo": "SBO:0000247", "kegg.compound": "C00116"}}, {"charge": 1, "name": "Choline", "formula": "C5H14NO", "compartment": "m", "id": "chol_m", "annotation": {"bigg.metabolite": "chol", "sbo": "SBO:0000247", "kegg.compound": "C00114"}}, {"charge": -2, "name": "Dihydroxyacetone phosphate", "formula": "C3H5O6P", "compartment": "m", "id": "dhap_m", "annotation": {"bigg.metabolite": "dhap", "sbo": "SBO:0000247", "kegg.compound": "C00111"}}, {"charge": -5, "name": "5-Phospho-alpha-D-ribose 1-diphosphate", "formula": "C5H8O14P3", "compartment": "m", "id": "prpp_m", "annotation": {"bigg.metabolite": "prpp", "sbo": "SBO:0000247", "kegg.compound": "C00119"}}, {"charge": 1, "name": "L-Isoleucyl-tRNA(Ile)", "formula": "C6H13NO2R", "compartment": "m", "id": "iletrna_m", "annotation": {"bigg.metabolite": "iletrna", "sbo": "SBO:0000247", "kegg.compound": "C03127"}}, {"charge": 1, "name": "L-Cysteinyl-tRNA(Cys)", "formula": "C3H7NO2SR", "compartment": "m", "id": "cystrna_m", "annotation": {"bigg.metabolite": "cystrna", "sbo": "SBO:0000247", "kegg.compound": "C03125"}}, {"charge": 0, "name": "L-Ascorbate", "formula": "C6H8O6", "compartment": "e", "id": "ascb-L_e", "annotation": {"bigg.metabolite": "ascb-L", "sbo": "SBO:0000247", "kegg.compound": "C00072"}}, {"charge": 0, "name": "L-Methionine", "formula": "C5H11NO2S", "compartment": "e", "id": "met-L_e", "annotation": {"bigg.metabolite": "met-L", "sbo": "SBO:0000247", "kegg.compound": "C00073"}}, {"charge": -3, "name": "Phosphoenolpyruvate", "formula": "C3H2O6P", "compartment": "e", "id": "pep_e", "annotation": {"bigg.metabolite": "pep", "sbo": "SBO:0000247", "kegg.compound": "C00074"}}, {"charge": -4, "name": "UTP", "formula": "C9H11N2O15P3", "compartment": "e", "id": "utp_e", "annotation": {"bigg.metabolite": "utp", "sbo": "SBO:0000247", "kegg.compound": "C00075"}}, {"charge": 1, "name": "Ornithine", "formula": "C5H13N2O2", "compartment": "e", "id": "orn_e", "annotation": {"bigg.metabolite": "orn", "sbo": "SBO:0000247", "kegg.compound": "C00077"}}, {"charge": 0, "name": "L-Tryptophan", "formula": "C11H12N2O2", "compartment": "e", "id": "trp-L_e", "annotation": {"bigg.metabolite": "trp-L", "sbo": "SBO:0000247", "kegg.compound": "C00078"}}, {"charge": 0, "name": "L-Phenylalanine", "formula": "C9H11NO2", "compartment": "e", "id": "phe-L_e", "annotation": {"bigg.metabolite": "phe-L", "sbo": "SBO:0000247", "kegg.compound": "C00079"}}, {"charge": -2, "name": "D-Ribulose 5-phosphate", "formula": "C5H9O8P", "compartment": "c", "id": "ru5p-D_c", "annotation": {"bigg.metabolite": "ru5p-D", "sbo": "SBO:0000247", "kegg.compound": "C00199"}}, {"charge": 0, "name": "Adenosylcobalamin", "formula": "C72H100CoN18O17P", "compartment": "c", "id": "adocbl_c", "annotation": {"bigg.metabolite": "adocbl", "sbo": "SBO:0000247", "kegg.compound": "C00194"}}, {"charge": -3, "name": "3-Phospho-D-glycerate", "formula": "C3H4O7P", "compartment": "c", "id": "3pg_c", "annotation": {"bigg.metabolite": "3pg", "sbo": "SBO:0000247", "kegg.compound": "C00197"}}, {"charge": -1, "name": "D-Glucuronate", "formula": "C6H9O7", "compartment": "c", "id": "glcur_c", "annotation": {"bigg.metabolite": "glcur", "sbo": "SBO:0000247", "kegg.compound": "C00191"}}, {"charge": -2, "name": "UDP-D-xylose", "formula": "C14H20N2O16P2", "compartment": "c", "id": "udpxyl_c", "annotation": {"bigg.metabolite": "udpxyl", "sbo": "SBO:0000247", "kegg.compound": "C00190"}}, {"charge": -3, "name": "dADP", "formula": "C10H12N5O9P2", "compartment": "m", "id": "dadp_m", "annotation": {"bigg.metabolite": "dadp", "sbo": "SBO:0000247", "kegg.compound": "C00206"}}, {"charge": 0, "name": "1-alkyl 2-acylglycerol 3-phosphoethanolamine", "formula": "C41.5654H80.5778N1.0O7.0P1.0", "compartment": "c", "id": "akac2gpe_c", "annotation": {"bigg.metabolite": "ak2gpe_hs", "sbo": "SBO:0000247", "kegg.compound": "C04475"}}, {"charge": -2, "name": "(alpha-D-mannosyl)2-beta-D-mannosyl-diacetylchitobiosyldiphosphodolichol", "formula": "C144H236N2O32P2", "compartment": "c", "id": "m2mpdol_c", "annotation": {"bigg.metabolite": ["m2macchitppdol", "m2mpdol_L", "m2mpdol_U"], "sbo": "SBO:0000247"}}, {"charge": 0, "name": "Protein C-terminal S-geranylgeranyl-L-cysteine methyl ester", "formula": "C26H43N2O3SR(C2H2NOR)n", "compartment": "c", "id": "protSgerCmet_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 0, "name": "Ubiquinone-8", "formula": "C49H74O4", "compartment": "c", "id": "q8_c", "annotation": {"bigg.metabolite": "q8", "sbo": "SBO:0000247"}}, {"charge": 0, "name": "Protein C-terminal S-geranylgeranyl-L-cysteine ", "formula": "C25H41N2O3SR(C2H2NOR)n", "compartment": "c", "id": "protSgerC_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 0, "name": "S-geranylgeranyl protein", "formula": "C25H41N2O3SR(C2H2NOR)n(C2H2NOR)n", "compartment": "c", "id": "protSger_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": 0, "name": "Dehydrodolichol, n=18", "formula": "C110H178O1", "compartment": "c", "id": "dedol_c", "annotation": {"sbo": "SBO:0000247"}}, {"charge": -2, "name": "Dehydrodolichol phosphate, n=18", "formula": "C110H177O4P1", "compartment": "c", "id": "dedolp_c", "annotation": {"bigg.metabolite": ["dedolp_L", "dedolp_U"], "sbo": "SBO:0000247"}}, {"charge": -1, "name": "1-Acyl-sn-glycero-3-phosphoglycerol", "formula": "C24.5654H44.5778O9.0P1.0", "compartment": "e", "id": "lpglyc_e", "annotation": {"bigg.metabolite": ["2agpg181", "2agpg180", "2agpg161", "2agpg160", "2agpg141", "2agpg140", "2agpg120", "1agpg181", "1agpg180", "1agpg161", "1agpg160", "1agpg141", "1agpg140", "1agpg120", "agpg_EC", "1glyc_hs"], "sbo": "SBO:0000247", "kegg.compound": "C18126"}}, {"charge": -1, "name": "1-Acyl-sn-glycero-3-phosphoserine", "formula": "C24.5654H43.5778N1.0O9.0P1.0", "compartment": "e", "id": "acg3ps_e", "annotation": {"sbo": "SBO:0000247", "kegg.compound": "C18125"}}, {"charge": -1, "name": "Ascaroside 18", "formula": "C17H31O6", "compartment": "e", "id": "ascr18_e", "annotation": {"sbo": "SBO:0000247"}}], "version": "1", "id": "iCEL1314"}